famotidine and Fibrosis studies

Famotidine: A competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion.

Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.

Research Excerpts

Excerpt	Relevance	Reference
"The gastrojet, a closed loop pH feedback infusion pump capable of maintaining intragastric pH at a target value by infusing H2 blockers at variable rates, was used to assess factors influencing the quantity of famotidine required to maintain intragastric pH above 4 for 24 hours in 34 fed patients with duodenal ulcers."	7.69	Maintenance of intragastric pH > 4 with famotidine in duodenal ulcer patients: factors influencing drug requirements. ( Deharvengt, MC; Delchier, JC; Elouaer Blanc, L; Roudot-Thoraval, F; Stanescu, L, 1994)
"The gastrojet, a closed loop pH feedback infusion pump capable of maintaining intragastric pH at a target value by infusing H2 blockers at variable rates, was used to assess factors influencing the quantity of famotidine required to maintain intragastric pH above 4 for 24 hours in 34 fed patients with duodenal ulcers."	3.69	Maintenance of intragastric pH > 4 with famotidine in duodenal ulcer patients: factors influencing drug requirements. ( Deharvengt, MC; Delchier, JC; Elouaer Blanc, L; Roudot-Thoraval, F; Stanescu, L, 1994)