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famotidine and Curling Ulcer

famotidine has been researched along with Curling Ulcer in 169 studies

Famotidine: A competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion.

Curling Ulcer: Acute stress DUODENAL ULCER, usually observed in patients with extensive third-degree burns.

Research Excerpts

ExcerptRelevanceReference
"We performed two 24-week double-blind trials (REDUCE-1 and -2 (Registration Endoscopic Studies to Determine Ulcer Formation of HZT-501 Compared with Ibuprofen: Efficacy and Safety Studies)) to assess whether double-dose famotidine given in a single-tablet combination with ibuprofen (HZT-501) significantly reduces gastric and duodenal ulcers as compared with ibuprofen."9.16Double-blind randomized trials of single-tablet ibuprofen/high-dose famotidine vs. ibuprofen alone for reduction of gastric and duodenal ulcers. ( Bello, AE; Grahn, AY; Kivitz, AJ; Laine, L; Schiff, MH; Taha, AS, 2012)
"To compare the effect and security of Jinghua Weikang Capsule (JWC) and famotidine in treating duodenal ulcer."9.12[Comparative study on Jinghua Weikang Capsule and famotidine in treating duodenal ulcer]. ( Chen, JX; Chen, JY; Ji, F, 2006)
"Fifty-three consecutive patients with active duodenal ulcer (DU) were randomly included in a double-blind, double-dummy study to test the healing and relapsing rate of two treatment regimens: famotidine 40 mg nocte for 4-8 weeks, followed by 20 mg for 12 months after healing of the ulcer and colloidal bismuth (CBS) (240 mg bid) for 4-8 weeks, followed by placebo maintenance treatment."9.08Colloid bismuth versus famotidine in the treatment and prevention of duodenal ulcer relapse: results of a double-blind, double dummy randomized study. ( Colombo, E; Fanti, L; Guslandi, M; Masci, E; Testoni, PA; Tittobello, A, 1995)
"To evaluate the effect of intravenous famotidine at a conventional dose of 40 mg/day on 24-h intragastric pH in patients with a bleeding duodenal ulcer, and to determine the dose required to maintain gastric pH > 6 by use of a Gastrojet (MIC, Switzerland) device (a pH meter-controlled programmable pump)."9.08Maintenance of gastric pH above 6 with intravenous famotidine in patients with a bleeding duodenal ulcer. ( Delchier, JC; el Amine, I; Elouaer-Blanc, L; Lamarque, D; Roudot-Thoraval, F; Stanescu, L, 1995)
"A trial was carried out to compare the efficacy and safety of ranitidine 300 mg die, famotidine 40 mg die and omeprazole 20 mg die in short-term treatment of bleeding duodenal ulcer in 3 groups of 15 patients."9.08[Comparison between ranitidine, famotidine, and omeprazole in the treatment of bleeding duodenal ulcer]. ( Maculotti, L; Pradella, P, 1995)
"We studied the efficacy of two doses of famotidine (20 mg and 40 mg, each given orally twice daily), as compared with placebo, in preventing peptic ulcers in 285 patients without peptic ulcers who were receiving long-term NSAID therapy for rheumatoid arthritis (82 percent) or osteoarthritis (18 percent)."9.08Famotidine for the prevention of gastric and duodenal ulcers caused by nonsteroidal antiinflammatory drugs. ( Cottrell, J; Hawkey, CJ; Hudson, N; Mann, SG; Russell, RI; Simon, TJ; Sturrock, RD; Swannell, AJ; Taha, AS; Trye, PN, 1996)
" Our purpose was to evaluate the occurrence of mycotic infection in patients with duodenal ulcer on anti-ulcer therapy and to compare the effects of cimetidine, famotidine, and omeprazole."9.08Candida overgrowth after treatment of duodenal ulcer. A comparison of cimetidine, famotidine, and omeprazole. ( Chakrabarti, A; Goenka, MK; Gupta, O; Kochhar, R; Kumar, A; Mehta, SK; Talwar, P, 1996)
"A multicentric double-blind trial comparing 600 mg/d of Zinc Acexamate (ACZ) and 40 mg/d of Famotidine (FMT) in the short term treatment of acute duodenal ulcer included 199 patients, diagnosed by endoscopy."9.08[A multicenter clinical trial. Zinc acexamate versus famotidine in the treatment of acute duodenal ulcer. Study Group of Zinc acexamate (new UP doses)]. ( Arenas, JI; Belda, O; de la Santa, Jw; Diago, A; Domínguez, A; Fernández, C; García-Plaza, A; Martín, L; Pallarés, A; Rodrigo, L, 1996)
"One hundred four patients with rheumatoid or osteoarthritis who had gastroduodenal ulceration received famotidine, 40 mg twice daily."9.08Famotidine for healing and maintenance in nonsteroidal anti-inflammatory drug-associated gastroduodenal ulceration. ( Cottrell, J; Hawkey, CJ; Hudson, N; Mann, SG; Russell, RI; Sturrock, RD; Swanell, AJ; Taha, AS; Trye, P, 1997)
"1) To validate risk factors for delayed healing of duodenal ulcers identified previously in a pilot study, and 2) To evaluate whether famotidine improves the rate of duodenal ulcer healing and pain relief, compared with ranitidine."9.07Risk factors for delayed healing of duodenal ulcers treated with famotidine and ranitidine. ( Maislin, G; Reynolds, JC; Schoen, RE; Zangari, GG, 1994)
"To verify whether a prolonged (therapeutic) treatment with ranitidine or famotidine may affect blood alcohol concentrations (BAC) in patients with duodenal ulcer (DU)."9.07Prolonged bedtime treatment with H2-receptor antagonists (ranitidine and famotidine) does not affect blood alcohol levels after ethanol ingestion in male patients with duodenal ulcer. ( Bertol, E; Casini, A; Mari, F; Pizzigallo, AM; Surrenti, C, 1994)
"Sixty patients with symptomatic duodenal ulcer were randomized to receive either omeprazole (20 mg each morning) or famotidine (40 mg at night time) for 2-4 weeks in a double-blind parallel group clinical trial."9.07Omeprazole versus famotidine in the healing and relapse of duodenal ulcer. ( Dasarathy, S; Misra, SC; Sharma, MP, 1993)
"The efficacy and safety of omeprazole, in 241 patients with active recurrent duodenal ulcer from 21 Italian centres, was studied in a multicentre double-blind randomized trial comparing 20 mg omeprazole o."9.07Omeprazole versus famotidine in the short-term treatment of duodenal ulcer disease. ( Annibale, B; Cassetta, MR; Delle Fave, G; Franceschi, M; Quatrini, M; Torsoli, A, 1992)
"In a double blind, multicenter, parallel group clinical trial in patients with symptomatic duodenal ulcers, 129 patients were randomized to receive either omeprazole 20 mg once daily (n = 65) or famotidine 40 mg once daily (n = 64) for 2 weeks, and if the ulcers were not healed, for a total of 4 weeks."9.07Comparative study of omeprazole and famotidine in the treatment of duodenal ulcer. ( Babu, S; Chaubal, C; Kumar, TR; Naidu, MU; Prasad, R; Reddy, DN; Shobha, JC; Subhash, S, 1992)
" In this 2:1 randomized, double-blind, multicentre trial lansoprazole 30 mg am was compared to 40 mg famotidine nocte in 264 out-patients suffering from uncomplicated duodenal ulcer."9.07Lansoprazole versus famotidine: efficacy and tolerance in the acute management of duodenal ulceration. ( Grymbowski, T; Hennig, U; Hotz, J; Kleinert, R; Schwarz, JA, 1992)
"A randomized controlled study comparing once-a-day morning and once-a-day bedtime administration of 40 mg famotidine in treating duodenal ulcers was carried out in 99 Japanese patients."9.07A comparative study of once-a-day morning and once-a-day bedtime administration of 40 mg famotidine in treating duodenal ulcers. ( Arita, M; Hoshiko, K; Iida, M; Maeda, K; Okada, M; Okada, Y; Sakamoto, K; Sakurai, T; Yao, T, 1992)
"5 mg twice daily), amantadine (100 mg nocte), or with the H2 blockers cimetidine (800 mg nocte), and famotidine (40 mg nocte) in 124 patients with endoscopically proven duodenal ulcer (DU)."9.07Dopamine agonists prevent duodenal ulcer relapse. A comparative study with famotidine and cimetidine. ( Duvnjak, M; Jagic, V; Mise, S; Petek, M; Rotkvic, I; Rucman, R; Seiwerth, S; Sikiric, P; Suchanek, E; Zjacic-Rotkvic, V, 1991)
"Famotidine, a new H2 antagonist in a dose of 40 mg qhs was tried in a clinical trial for the treatment of duodenal ulcer in 25 patients and compared with other H2 antagonists."9.06Treatment of acute duodenal ulcers with famotidine and its comparison with other H2 blockers. ( Akhtar, MA; Khan, MA; Rashid, P, 1990)
"The efficacy and safety of famotidine and ranitidine in the treatment of active duodenal ulcer were compared in a multicentre, randomized, double-blind study."9.06A multicentre, randomized, double-blind study comparing nocte famotidine or ranitidine for the treatment of active duodenal ulceration. ( Alcalá Santaella, R; Alvárez, E; Castellanos, P; Guardia, J; Guarner, L; Ortiz, J; Pajares, J; Pesquera, R; Piqué, J; Pita, L, 1989)
"Six asymptomatic, non-smoking men with endoscopically proven duodenal ulcer disease received single nocturnal doses of placebo, 40 mg famotidine and 300 mg ranitidine each for 1 week prior to serial measurement of pH, peptic activity and serum gastrin concentrations over 24 h and of acid output."9.06A single night-time dose of famotidine is equivalent to ranitidine in decreasing 24-hour gastric acidity in asymptomatic duodenal ulcer subjects. ( Kirdeikis, J; Marriage, B; Pinchbeck, BR; Prat, A; Thomson, AB; Zuk, L, 1989)
"Famotidine (40 mg) and 800 mg cimetidine as single night-time doses were compared in a randomized, double-blind, multicentre study of acute treatment for duodenal ulceration."9.06Single night-time doses of 40 mg famotidine or 800 mg cimetidine in the treatment of duodenal ulcer. ( Booth, SN; Cochran, KM; Cottrell, J; Crowe, J; Dickinson, RJ; Kennedy, NP; Lee, FI; Mann, SG, 1989)
"The efficacy and safety of famotidine and ranitidine in the treatment of active duodenal ulcer were compared in a multicenter, randomized double-blind study."9.06A multicenter, randomized, double-blind study comparing once-daily bedtime administration of famotidine and ranitidine in the short-term treatment of active duodenal ulcer. ( Alcalá Santaella, R; Alvárez, E; Castellanos, P; Guardia, J; Guarner, L; Ortiz, J; Pajares, J; Pesquera, R; Pique, J; Pita, L, 1989)
"The efficacy and safety of famotidine and ranitidine in the treatment of active duodenal ulcer were compared in a multicenter, randomized double-blind study."9.06A multicenter, randomized, double-blind study comparing a daily bedtime administration of famotidine and ranitidine in short-term treatment of active duodenal ulcer. ( Alcalá-Santaella, R; Alvárez, E; Castellanos, P; Guardia, J; Guarner, L; Ortiz, J; Pajares, J; Pesquera, R; Piqué, J; Pita, L, 1989)
"This multicentric, double-blind and prospective study, which involved 41 French Gastroenterology Units, was designed to evaluate the efficacy and safety of famotidine, 40 mg at bedtime, compared to single dose ranitidine, 300 mg, in promoting the healing of duodenal ulcer."9.06[Comparative efficacy of famotidine and ranitidine in the treatment of acute-phase duodenal ulcer. A French comparative therapeutic trial]. ( Delvaux, M; Hagège, CG; Ribet, A, 1989)
"In a double-blind multicenter trial, 100 patients with active duodenal ulcer were treated with a single nocturnal dose of famotidine 40 mg or ranitidine 300 mg."9.06Treatment of active duodenal ulcers with famotidine. A double-blind comparison with ranitidine. ( Gugler, R; Rohner, HG, 1986)
"Famotidine, a new long-acting histamine (H2)-receptor antagonist, has recently been shown to be more effective than placebo in healing active duodenal ulcer."9.06A multicenter, randomized, double-blind study comparing famotidine with ranitidine in the treatment of active duodenal ulcer disease. ( McCullough, AJ, 1986)
"One hundred and thirty-two patients with endoscopically confirmed duodenal ulcers were entered into a 4-6-week double-blind trial of famotidine (Fm) and ranitidine (Rn)."9.06Comparison of famotidine 40 mg with ranitidine 300 mg at night in short-term duodenal ulcer healing. A South African multicentre study. ( Marks, IN; Wright, JP, 1987)
"A multicenter, double-blind, randomized, controlled study was conducted in 234 duodenal ulcer patients to compare the efficacy and safety of the H2-receptor antagonists famotidine and ranitidine in the treatment of duodenal ulcer."9.06Comparison of once-daily bedtime administration of famotidine and ranitidine in the short-term treatment of duodenal ulcer. A multicenter, double-blind, controlled study. ( Boero, A; Camarri, E; Crespi, M; De Pretis, G; Dobrilla, G; Fontana, G; Ideo, G; Manenti, F; Marenco, G; Piazzi, L, 1987)
" The effects have been compared of ranitidine and famotidine on PGE2 content in duodenal ulcer patients."9.06Action of famotidine and ranitidine on prostaglandin E2 (PGE2) content of fundic and duodenal mucosa in duodenal ulcer patients. ( Carlei, F; D'Alessandro, MD; Lezoche, E; Lomanto, D; Mariani, P; Martelli, A; Nardovino, M; Speranza, V; Vagni, V, 1987)
"The efficacy of famotidine, a potent new long-acting H2 receptor antagonist, was compared with cimetidine in 78 patients with endoscopically proven acute duodenal ulcers."9.06Famotidine versus cimetidine in the treatment of acute duodenal ulcer. Double-blind, randomized clinical trial comparing nocturnal administration of 40 mg famotidine to 800 mg cimetidine. ( Fölsch, UR; Hartmann, H, 1988)
"Famotidine was compared to ranitidine in a short-term study on the treatment of duodenal ulcer."9.06Famotidine in the short and long-term treatment of duodenal ulcer. ( Bettarello, A; Coelho, LG; de Paula Castro, L; Dias Avelar, C; Eisig, JN; Massuda, HK; Villalobos, JJ; Zaterka, S, 1988)
"An integrated analysis of the fifteen published prospective multicenter studies that have examined the safety and efficacy of famotidine for the short-term (13) and maintenance (2) therapy of duodenal ulcer included over 2,600 patients."9.06Famotidine in the management of duodenal ulcer: an analysis of multicenter findings worldwide. ( Reynolds, JC, 1988)
"Three double blind crossover studies were carried out to assess the ability of primed infusions of famotidine to raise intragastric pH over 24 hours in 12 duodenal ulcer patients."9.06Continuous intravenous infusions of famotidine maintain high intragastric pH in duodenal ulcer. ( Kaufman, D; Kempf, M; Merki, HS; Neumann, J; Röhmel, J; Walt, RP; Witzel, L, 1988)
"In 11 duodenal ulcer patients, the antisecretory effects of bedtime famotidine 40 mg were compared to those obtained with ranitidine 300 mg and placebo by means of continuous 24-hour intragastric pH monitoring."9.06Continuous 24-hour intragastric pH monitoring in the evaluation of the effect of a nightly dose of famotidine, ranitidine and placebo on gastric acidity of patients with duodenal ulcer. ( Celle, G; Di Timoteo, E; Magnolia, MR; Mela, GS; Savarino, V; Scalabrini, P, 1987)
"185 patients with endoscopically proven duodenal ulcers were randomly allocated to treatment with either famotidine 40 mg nocte, 20 mg bid, 40 mg bid or ranitidine 150 mg bid for 2-8 weeks in a prospective double-blind study."9.05[Famotidine versus ranitidine in the acute treatment of duodenal ulcer. A multicenter comparative study in Germany]. ( Dammann, HG; Jakob, G; Miederer, SE; Müller, P; Ottenjann, R; Paul, F; Scholten, T; Schütz, E; Seifert, E; Simon, B, 1985)
"One-hundred and eight-three patients with endoscopically proven duodenal ulcers, enrolled in this prospective, double-blind study, were randomly allocated to receive famotidine 40 mg once at night, 20 mg twice daily, 40 mg twice daily, or ranitidine 150 mg twice daily for 2-8 weeks."9.05Famotidine versus ranitidine for the short-term treatment of duodenal ulcer. ( Dammann, HG; Jakob, G; Miederer, SE; Müller, P; Ottenjann, R; Paul, F; Scholten, T; Schütz, E; Seifert, E; Simon, B, 1985)
"The new H2 receptor antagonist, famotidine, has been tested in open and double-blind studies in over 2,000 acute duodenal or gastric ulcer patients as well as in the maintenance of chronic duodenal ulcer patients."9.05Famotidine in the treatment of gastric and duodenal ulceration: overview of clinical experience. ( Bianchi Porro, G, 1985)
"The aim of this study was to gain experience concerning efficacy and safety of famotidine, the new H2-receptor antagonist, for the maintenance of duodenal ulcer disease."9.05[Famotidine versus placebo in prevention of the recurrence of duodenal ulcer disease. A multicenter study in Germany, Austria and Italy]. ( Baglioni, A; Barbara, L; Bianchi-Porro, G; Blasi, A; Canelli, B; Cheli, R; Dal Monte, R; Dammann, HG; Francavilla, A; Hentschel, E, 1985)
"Although anti-inflammatory doses of ibuprofen are very effective in treating the signs and symptoms of osteoarthritis (OA), they come with an increased risk for gastrointestinal damage which can limit their use and decrease patient adherence to therapy."8.90Risk of upper gastrointestinal ulcers in patients with osteoarthritis receiving single-tablet ibuprofen/famotidine versus ibuprofen alone: pooled efficacy and safety analyses of two randomized, double-blind, comparison trials. ( Bello, AE; Grahn, AY; Holt, RJ; Kent, JD; Rice, P, 2014)
"The aim was to compare the clinical efficacy of lansoprazole with the efficacies of ranitidine and famotidine in order to rank this drug in the hierarchy of duodenal ulcer treatments."8.79Meta-analysis of randomized clinical trials comparing lansoprazole with ranitidine or famotidine in the treatment of acute duodenal ulcer. ( Agostini, H; Lemaire, M; Poynard, T, 1995)
"To study the effects of growth factors on experimental duodenal ulcer healing in indomethacin-treated rats."7.72Effect of exogenous administration of transforming growth factor-beta and famotidine on the healing of duodenal ulcer under the impact of indomethacin. ( Arceiz, E; Lanas, A; Ortego, J; Pérez-Aisa, A; Sainz, R; Sopeña, F, 2003)
"Duodenal ulcer was induced in male Wistar rats with acetic acid."7.71[Effect of exogenous administration of platelet-derived growth factor and epidermal growth factor on duodenal ulcer healing in rats treated with indomethacin]. ( Arceiz Gonzalo, E; Lanas Arbeloa, A; Ortego Díez De Retana, J; Pérez Aisa, A; Sainz Samitier, R; Sopeña Biarge, F, 2002)
"The gastrojet, a closed loop pH feedback infusion pump capable of maintaining intragastric pH at a target value by infusing H2 blockers at variable rates, was used to assess factors influencing the quantity of famotidine required to maintain intragastric pH above 4 for 24 hours in 34 fed patients with duodenal ulcers."7.69Maintenance of intragastric pH > 4 with famotidine in duodenal ulcer patients: factors influencing drug requirements. ( Deharvengt, MC; Delchier, JC; Elouaer Blanc, L; Roudot-Thoraval, F; Stanescu, L, 1994)
"The combination of sucralfate (SUC) and famotidine (FAM) at subtherapeutic dose on cysteamine-induced duodenal ulcers (3 x 250 mg/kg) in female rats was studied."7.69The effect of the combination therapy with sucralfate and famotidine on experimentally induced duodenal ulcers in rats. ( Zupancic, P, 1996)
"The studies of microsomal liver enzyme activity by means of a respiratory test with 14C-aminopyrine (ABT) were carried out in 20 patients with duodenal ulcer treated for eight weeks with famotidine."7.68[Evaluation of microsomal enzyme function in the liver in patients with duodenal ulcer treated with famotidine]. ( Grzeszczak, W; Piotrowska, E; Piotrowski, J, 1993)
"The liver microsomal enzymes activity was measured by aminopyrine breath test in 20 subjects with duodenal ulcer disease treated with famotidine for 8 weeks."7.68[Assessment of microsomal enzyme function in liver of patients with duodenal ulcer treated with famotidine]. ( Grzeszczak, W; Piotrowska, E; Piotrowski, J, 1993)
"In this open trial, 25 patients with identified duodenal ulcers were given long-term therapy of a single evening dose of 20 mg famotidine."7.68[Prevention of the recurrence of duodenal ulcer with famotidine. Report of experiences with long-term therapy in an open clinical study]. ( Judmaier, G, 1992)
"Fifty three patients with duodenal ulcer were treated with 40 mg of famotidine at bed time."7.67A single nocte dose of famotidine in the treatment of duodenal ulcer. ( Ahmad, W; Qureshi, H; Zuberi, SJ, 1989)
"The aim of this study was to evaluate the clinical efficacy of short and long-term treatment with famotidine 40 mg/daily at bed time in duodenal ulcer disease."7.67[Famotidine in the short and long term treatment of duodenal ulcer: clinical and physiopathologic study]. ( Dal Santo, L; Di Mario, F; Gottardello, L; Grassi, SA; Naccarato, R; Pasqualetti, P; Tessaro, P; Vianello, F; Vio, A, 1989)
"The H2-receptor antagonists mifentidine, famotidine, cimetidine and ranitidine were examined for their ability to prevent the duodenal ulcer caused by mepirizole (250 mg/kg p."7.67Effect of mifentidine on mepirizole-induced duodenal ulcer in the rat. ( Brambilla, A; De Paoli, AM; Ghiorzi, A; Giachetti, A, 1987)
"Healing processes of duodenal ulcers induced by mepirizole and effects of several drugs on the ulcer healing were studied in rats."7.66Effects of antiulcer agents on healing of mepirizole-induced duodenal ulcers in rats. ( Ishihara, Y; Okabe, S, 1983)
"for the prevention of duodenal ulcer recurrence."6.67A controlled study of 20 mg famotidine nocte vs. 150 mg ranitidine nocte for the prevention of duodenal ulcer relapse. ( Barbara, L; Bianchi Porro, G; Blasi, A; Bovero, E; Capurso, L; Cheli, R; Corinaldesi, R; Koch, M; Lazzaroni, M; Mangiameli, A, 1991)
"Famotidine appears to be an effective and safe once-a-day therapy for the treatment of acute duodenal ulcer disease."6.66A multicenter, double-blind, randomized, placebo-controlled comparison of nocturnal and twice-a-day famotidine in the treatment of active duodenal ulcer disease. ( Berman, R; Gitlin, N; Mantell, G; McCullough, AJ; Smith, JL, 1987)
" In view of possible increased patient compliance with a simplified dosage regimen, famotidine 40 mg h."6.66Review of an extensive worldwide study of a new H2-receptor antagonist, famotidine, as compared to ranitidine in the treatment of acute duodenal ulcer. ( Bianchi Porro, G; Cook, T; Dicenta, C; Humphries, TJ, 1987)
"Ibuprofen/famotidine was generally well tolerated, with a tolerability profile consistent with those established for the individual agents."6.49Fixed-dose ibuprofen/famotidine: a review of its use to reduce the risk of gastric and duodenal ulcers in patients requiring NSAID therapy. ( Deeks, ED, 2013)
" Recurrent upper GI bleeding occurred in one patient receiving lansoprazole (duodenal ulcer) and three receiving famotidine (two gastric ulcers and one duodenal ulcer)."5.34Prevention of recurrent idiopathic gastroduodenal ulcer bleeding: a double-blind, randomised trial. ( Chan, FKL; Ching, JYL; Chiu, PWY; Lau, JYW; Lau, LHS; Ling, RHY; Tse, YK; Wong, GLH; Wong, VWS, 2020)
"Operative management also reduces recurrence rates, which, however, are commoner in patients coming to surgery nowadays."5.28High doses of ranitidine in maintenance therapy of duodenal ulcer patients. ( Lee, FI, 1990)
" The therapy was prolonged for two years with the same dosage at the beginning and later with half doses without any relapse and secondary effects."5.28[Duodenal ulcer, study of gastric secretion and rational treatment with famotidine in different doses]. ( Idotta, G; Morucci, P; Santoro, E; Scutari, F, 1989)
"We performed two 24-week double-blind trials (REDUCE-1 and -2 (Registration Endoscopic Studies to Determine Ulcer Formation of HZT-501 Compared with Ibuprofen: Efficacy and Safety Studies)) to assess whether double-dose famotidine given in a single-tablet combination with ibuprofen (HZT-501) significantly reduces gastric and duodenal ulcers as compared with ibuprofen."5.16Double-blind randomized trials of single-tablet ibuprofen/high-dose famotidine vs. ibuprofen alone for reduction of gastric and duodenal ulcers. ( Bello, AE; Grahn, AY; Kivitz, AJ; Laine, L; Schiff, MH; Taha, AS, 2012)
"To compare the effect and security of Jinghua Weikang Capsule (JWC) and famotidine in treating duodenal ulcer."5.12[Comparative study on Jinghua Weikang Capsule and famotidine in treating duodenal ulcer]. ( Chen, JX; Chen, JY; Ji, F, 2006)
"Fifty-three consecutive patients with active duodenal ulcer (DU) were randomly included in a double-blind, double-dummy study to test the healing and relapsing rate of two treatment regimens: famotidine 40 mg nocte for 4-8 weeks, followed by 20 mg for 12 months after healing of the ulcer and colloidal bismuth (CBS) (240 mg bid) for 4-8 weeks, followed by placebo maintenance treatment."5.08Colloid bismuth versus famotidine in the treatment and prevention of duodenal ulcer relapse: results of a double-blind, double dummy randomized study. ( Colombo, E; Fanti, L; Guslandi, M; Masci, E; Testoni, PA; Tittobello, A, 1995)
"To evaluate the effect of intravenous famotidine at a conventional dose of 40 mg/day on 24-h intragastric pH in patients with a bleeding duodenal ulcer, and to determine the dose required to maintain gastric pH > 6 by use of a Gastrojet (MIC, Switzerland) device (a pH meter-controlled programmable pump)."5.08Maintenance of gastric pH above 6 with intravenous famotidine in patients with a bleeding duodenal ulcer. ( Delchier, JC; el Amine, I; Elouaer-Blanc, L; Lamarque, D; Roudot-Thoraval, F; Stanescu, L, 1995)
"A trial was carried out to compare the efficacy and safety of ranitidine 300 mg die, famotidine 40 mg die and omeprazole 20 mg die in short-term treatment of bleeding duodenal ulcer in 3 groups of 15 patients."5.08[Comparison between ranitidine, famotidine, and omeprazole in the treatment of bleeding duodenal ulcer]. ( Maculotti, L; Pradella, P, 1995)
"We studied the efficacy of two doses of famotidine (20 mg and 40 mg, each given orally twice daily), as compared with placebo, in preventing peptic ulcers in 285 patients without peptic ulcers who were receiving long-term NSAID therapy for rheumatoid arthritis (82 percent) or osteoarthritis (18 percent)."5.08Famotidine for the prevention of gastric and duodenal ulcers caused by nonsteroidal antiinflammatory drugs. ( Cottrell, J; Hawkey, CJ; Hudson, N; Mann, SG; Russell, RI; Simon, TJ; Sturrock, RD; Swannell, AJ; Taha, AS; Trye, PN, 1996)
" Our purpose was to evaluate the occurrence of mycotic infection in patients with duodenal ulcer on anti-ulcer therapy and to compare the effects of cimetidine, famotidine, and omeprazole."5.08Candida overgrowth after treatment of duodenal ulcer. A comparison of cimetidine, famotidine, and omeprazole. ( Chakrabarti, A; Goenka, MK; Gupta, O; Kochhar, R; Kumar, A; Mehta, SK; Talwar, P, 1996)
"A multicentric double-blind trial comparing 600 mg/d of Zinc Acexamate (ACZ) and 40 mg/d of Famotidine (FMT) in the short term treatment of acute duodenal ulcer included 199 patients, diagnosed by endoscopy."5.08[A multicenter clinical trial. Zinc acexamate versus famotidine in the treatment of acute duodenal ulcer. Study Group of Zinc acexamate (new UP doses)]. ( Arenas, JI; Belda, O; de la Santa, Jw; Diago, A; Domínguez, A; Fernández, C; García-Plaza, A; Martín, L; Pallarés, A; Rodrigo, L, 1996)
"One hundred four patients with rheumatoid or osteoarthritis who had gastroduodenal ulceration received famotidine, 40 mg twice daily."5.08Famotidine for healing and maintenance in nonsteroidal anti-inflammatory drug-associated gastroduodenal ulceration. ( Cottrell, J; Hawkey, CJ; Hudson, N; Mann, SG; Russell, RI; Sturrock, RD; Swanell, AJ; Taha, AS; Trye, P, 1997)
"1) To validate risk factors for delayed healing of duodenal ulcers identified previously in a pilot study, and 2) To evaluate whether famotidine improves the rate of duodenal ulcer healing and pain relief, compared with ranitidine."5.07Risk factors for delayed healing of duodenal ulcers treated with famotidine and ranitidine. ( Maislin, G; Reynolds, JC; Schoen, RE; Zangari, GG, 1994)
"To verify whether a prolonged (therapeutic) treatment with ranitidine or famotidine may affect blood alcohol concentrations (BAC) in patients with duodenal ulcer (DU)."5.07Prolonged bedtime treatment with H2-receptor antagonists (ranitidine and famotidine) does not affect blood alcohol levels after ethanol ingestion in male patients with duodenal ulcer. ( Bertol, E; Casini, A; Mari, F; Pizzigallo, AM; Surrenti, C, 1994)
"Sixty patients with symptomatic duodenal ulcer were randomized to receive either omeprazole (20 mg each morning) or famotidine (40 mg at night time) for 2-4 weeks in a double-blind parallel group clinical trial."5.07Omeprazole versus famotidine in the healing and relapse of duodenal ulcer. ( Dasarathy, S; Misra, SC; Sharma, MP, 1993)
"The purpose of the work was an evaluation of duodenal ulcer recurrence rate in patients with a history of at least two years of ulcer treated during one year with the preparation Ulfamid (famotidine) Krka in a maintenance dose of 20 mg before sleep."5.07[Clinical evaluation of one-year controlled studies of duodenal ulcer recurrence rate in patients treated with the preparation Ulfamid]. ( Gabryelewicz, A; Jaroszewicz-Heigelmann, H; Kosidło, S; Marlicz, K, 1993)
" Double-blind comparative studies with a beta-blocker, famotidine, in gastric ulcer (study 1) and in duodenal ulcer (study 2) were conducted."5.07[Double-blind controlled-clinical trials of lansoprazole in the treatment of peptic ulcer]. ( Ogawa, N, 1992)
"We monitored 24-hour gastric acidity in 16 resistant duodenal ulcer patients treated with ranitidine 300 mg hora somni (9 cases) and famotidine 40 mg hora somni (7 cases) for 3 months."5.07Duration of acid suppression in H2-antagonist nonresponders. ( Celle, G; Cutela, P; Mela, GS; Mele, MR; Savarino, V; Zentilin, P, 1992)
"The efficacy and safety of omeprazole, in 241 patients with active recurrent duodenal ulcer from 21 Italian centres, was studied in a multicentre double-blind randomized trial comparing 20 mg omeprazole o."5.07Omeprazole versus famotidine in the short-term treatment of duodenal ulcer disease. ( Annibale, B; Cassetta, MR; Delle Fave, G; Franceschi, M; Quatrini, M; Torsoli, A, 1992)
"In a double blind, multicenter, parallel group clinical trial in patients with symptomatic duodenal ulcers, 129 patients were randomized to receive either omeprazole 20 mg once daily (n = 65) or famotidine 40 mg once daily (n = 64) for 2 weeks, and if the ulcers were not healed, for a total of 4 weeks."5.07Comparative study of omeprazole and famotidine in the treatment of duodenal ulcer. ( Babu, S; Chaubal, C; Kumar, TR; Naidu, MU; Prasad, R; Reddy, DN; Shobha, JC; Subhash, S, 1992)
"In a two center open uncontrolled clinical trial, the efficacy of a single evening dose of 40 mg famotidine (Ulcusan) was studied in a total of 37 patients (20 with chronic duodenal ulcers, 9 with recurring and 8 with acute gastric ulcers)."5.07[Therapy of peptic ulcers with famotidine. Report of experiences with an open clinical study]. ( Dragosics, B; Okulski, G; Weiss, W, 1992)
"In a prospective, randomized, single-blind, single-center, controlled study, we compared the effectiveness of single doses of cimetidine 800 mg, ranitidine 300 mg, and famotidine-40 mg given either as evening or morning doses for duodenal ulcer healing."5.07Morning versus evening dose: a comparison of three H2-receptor blockers in duodenal ulcer healing. ( Affarah, HB; Khasawneh, SM, 1992)
" In this 2:1 randomized, double-blind, multicentre trial lansoprazole 30 mg am was compared to 40 mg famotidine nocte in 264 out-patients suffering from uncomplicated duodenal ulcer."5.07Lansoprazole versus famotidine: efficacy and tolerance in the acute management of duodenal ulceration. ( Grymbowski, T; Hennig, U; Hotz, J; Kleinert, R; Schwarz, JA, 1992)
"A randomized controlled study comparing once-a-day morning and once-a-day bedtime administration of 40 mg famotidine in treating duodenal ulcers was carried out in 99 Japanese patients."5.07A comparative study of once-a-day morning and once-a-day bedtime administration of 40 mg famotidine in treating duodenal ulcers. ( Arita, M; Hoshiko, K; Iida, M; Maeda, K; Okada, M; Okada, Y; Sakamoto, K; Sakurai, T; Yao, T, 1992)
"We evaluated the circadian pattern of gastric acidity by prolonged intraluminal pHmetry in 15 "responder" and 10 "nonresponder" duodenal ulcer patients after nocturnal administration of placebo, ranitidine, and famotidine."5.07Prolonged gastric pH monitoring in responder and nonresponder duodenal ulcer patients: response to placebo and to H2-blocker administration. ( Arossa, W; De la Pierre, M; Masoero, G; Rossanino, A, 1991)
"5 mg twice daily), amantadine (100 mg nocte), or with the H2 blockers cimetidine (800 mg nocte), and famotidine (40 mg nocte) in 124 patients with endoscopically proven duodenal ulcer (DU)."5.07Dopamine agonists prevent duodenal ulcer relapse. A comparative study with famotidine and cimetidine. ( Duvnjak, M; Jagic, V; Mise, S; Petek, M; Rotkvic, I; Rucman, R; Seiwerth, S; Sikiric, P; Suchanek, E; Zjacic-Rotkvic, V, 1991)
"Famotidine, a new H2 antagonist in a dose of 40 mg qhs was tried in a clinical trial for the treatment of duodenal ulcer in 25 patients and compared with other H2 antagonists."5.06Treatment of acute duodenal ulcers with famotidine and its comparison with other H2 blockers. ( Akhtar, MA; Khan, MA; Rashid, P, 1990)
" We used this technique to evaluate the effects on gastric acidity of placebo, ranitidine 150mg, famotidine 20mg and nizatidine 150mg in fifteen patients with healed duodenal ulcer."5.06Continuous intragastric pH monitoring: a real progress in the assessment of antisecretory drugs. ( Savarino, V, 1990)
"In a double-blind randomised trial, 40 patients with active gastric or duodenal ulcer were treated with a single nocturnal dose of famotidine 40 mg or ranitidine 300 mg for 4 to 8 weeks."5.06Double-blind comparison of the safety and efficacy of famotidine with ranitidine in patients with endoscopically diagnosed peptic ulcer. ( Bowalekar, SK; Jha, RJ; Nanivadekar, SA; Navani, SR; Oke, VG; Patel, HD; Raghu, CN; Sawant, PD; Shroff, CP, 1990)
"A multicenter, open study was designed to evaluate the efficacy and tolerability of a novel and potent H2 receptor antagonist, Famotidine, in the treatment of duodenal ulcer."5.06[Famotidine in the treatment of duodenal peptic ulcer]. ( Berrios, J; Bussalleu, A; Espejo, H; Espinoza, R; Farfán, G; Galarza, J; Guerra, J; Nago, A; Simich, C; Valladares, G, 1990)
"The efficacy and safety of famotidine and ranitidine in the treatment of active duodenal ulcer were compared in a multicentre, randomized, double-blind study."5.06A multicentre, randomized, double-blind study comparing nocte famotidine or ranitidine for the treatment of active duodenal ulceration. ( Alcalá Santaella, R; Alvárez, E; Castellanos, P; Guardia, J; Guarner, L; Ortiz, J; Pajares, J; Pesquera, R; Piqué, J; Pita, L, 1989)
"Six asymptomatic, non-smoking men with endoscopically proven duodenal ulcer disease received single nocturnal doses of placebo, 40 mg famotidine and 300 mg ranitidine each for 1 week prior to serial measurement of pH, peptic activity and serum gastrin concentrations over 24 h and of acid output."5.06A single night-time dose of famotidine is equivalent to ranitidine in decreasing 24-hour gastric acidity in asymptomatic duodenal ulcer subjects. ( Kirdeikis, J; Marriage, B; Pinchbeck, BR; Prat, A; Thomson, AB; Zuk, L, 1989)
"Famotidine (40 mg) and 800 mg cimetidine as single night-time doses were compared in a randomized, double-blind, multicentre study of acute treatment for duodenal ulceration."5.06Single night-time doses of 40 mg famotidine or 800 mg cimetidine in the treatment of duodenal ulcer. ( Booth, SN; Cochran, KM; Cottrell, J; Crowe, J; Dickinson, RJ; Kennedy, NP; Lee, FI; Mann, SG, 1989)
"The efficacy and safety of famotidine and ranitidine in the treatment of active duodenal ulcer were compared in a multicenter, randomized double-blind study."5.06A multicenter, randomized, double-blind study comparing once-daily bedtime administration of famotidine and ranitidine in the short-term treatment of active duodenal ulcer. ( Alcalá Santaella, R; Alvárez, E; Castellanos, P; Guardia, J; Guarner, L; Ortiz, J; Pajares, J; Pesquera, R; Pique, J; Pita, L, 1989)
"The efficacy and safety of famotidine and ranitidine in the treatment of active duodenal ulcer were compared in a multicenter, randomized double-blind study."5.06A multicenter, randomized, double-blind study comparing a daily bedtime administration of famotidine and ranitidine in short-term treatment of active duodenal ulcer. ( Alcalá-Santaella, R; Alvárez, E; Castellanos, P; Guardia, J; Guarner, L; Ortiz, J; Pajares, J; Pesquera, R; Piqué, J; Pita, L, 1989)
"This multicentric, double-blind and prospective study, which involved 41 French Gastroenterology Units, was designed to evaluate the efficacy and safety of famotidine, 40 mg at bedtime, compared to single dose ranitidine, 300 mg, in promoting the healing of duodenal ulcer."5.06[Comparative efficacy of famotidine and ranitidine in the treatment of acute-phase duodenal ulcer. A French comparative therapeutic trial]. ( Delvaux, M; Hagège, CG; Ribet, A, 1989)
"In a double-blind multicenter trial, 100 patients with active duodenal ulcer were treated with a single nocturnal dose of famotidine 40 mg or ranitidine 300 mg."5.06Treatment of active duodenal ulcers with famotidine. A double-blind comparison with ranitidine. ( Gugler, R; Rohner, HG, 1986)
"Famotidine, a new long-acting histamine (H2)-receptor antagonist, has recently been shown to be more effective than placebo in healing active duodenal ulcer."5.06A multicenter, randomized, double-blind study comparing famotidine with ranitidine in the treatment of active duodenal ulcer disease. ( McCullough, AJ, 1986)
"One hundred and thirty-two patients with endoscopically confirmed duodenal ulcers were entered into a 4-6-week double-blind trial of famotidine (Fm) and ranitidine (Rn)."5.06Comparison of famotidine 40 mg with ranitidine 300 mg at night in short-term duodenal ulcer healing. A South African multicentre study. ( Marks, IN; Wright, JP, 1987)
"A multicenter, double-blind, randomized, controlled study was conducted in 234 duodenal ulcer patients to compare the efficacy and safety of the H2-receptor antagonists famotidine and ranitidine in the treatment of duodenal ulcer."5.06Comparison of once-daily bedtime administration of famotidine and ranitidine in the short-term treatment of duodenal ulcer. A multicenter, double-blind, controlled study. ( Boero, A; Camarri, E; Crespi, M; De Pretis, G; Dobrilla, G; Fontana, G; Ideo, G; Manenti, F; Marenco, G; Piazzi, L, 1987)
" The effects have been compared of ranitidine and famotidine on PGE2 content in duodenal ulcer patients."5.06Action of famotidine and ranitidine on prostaglandin E2 (PGE2) content of fundic and duodenal mucosa in duodenal ulcer patients. ( Carlei, F; D'Alessandro, MD; Lezoche, E; Lomanto, D; Mariani, P; Martelli, A; Nardovino, M; Speranza, V; Vagni, V, 1987)
"Eight patients with previous duodenal ulcer in symptomatic remission underwent continuous intraluminal pH monitoring on five separate occasions to compare the effects on 24-h intragastric acidity of placebo, 300 mg ranitidine at night, 150 mg ranitidine twice daily, 40 mg famotidine at night, and 20 mg famotidine twice daily."5.06Once and twice daily doses of H2 antagonists revisited, using continuous intragastric pH monitoring. ( Celle, G; Fera, G; Mela, GS; Savarino, V; Scalabrini, P; Sumberaz, A; Zentilin, P, 1988)
"The effect of administering low doses of famotidine or ranitidine alone or in combination with an M1-receptor-selective antagonist, pirenzepine, on night intragastric acidity was evaluated in 16 active duodenal ulcer patients to verify 1) whether anticholinergics and H2-antagonists have a synergic effect on inhibition of night gastric acidity, and 2) whether patients with vagal hypertone are more sensitive to anticholinergics than the remainder of the duodenal ulcer population."5.06Do anticholinergics interact with histamine H2 receptor antagonists on night intragastric acidity in active duodenal ulcer patients? ( Clausi, GG; Farinelli, M; Farroni, F; Fiorucci, S; Morelli, A; Pelli, MA; Santucci, L, 1988)
"The efficacy of famotidine, a potent new long-acting H2 receptor antagonist, was compared with cimetidine in 78 patients with endoscopically proven acute duodenal ulcers."5.06Famotidine versus cimetidine in the treatment of acute duodenal ulcer. Double-blind, randomized clinical trial comparing nocturnal administration of 40 mg famotidine to 800 mg cimetidine. ( Fölsch, UR; Hartmann, H, 1988)
"Famotidine was compared to ranitidine in a short-term study on the treatment of duodenal ulcer."5.06Famotidine in the short and long-term treatment of duodenal ulcer. ( Bettarello, A; Coelho, LG; de Paula Castro, L; Dias Avelar, C; Eisig, JN; Massuda, HK; Villalobos, JJ; Zaterka, S, 1988)
"An integrated analysis of the fifteen published prospective multicenter studies that have examined the safety and efficacy of famotidine for the short-term (13) and maintenance (2) therapy of duodenal ulcer included over 2,600 patients."5.06Famotidine in the management of duodenal ulcer: an analysis of multicenter findings worldwide. ( Reynolds, JC, 1988)
"In order to assess whether dinnertime administration of a once daily dose of famotidine is more advantageous than a bedtime dose in suppressing evening and nocturnal gastric acidity, we gave nine patients with a past history of duodenal ulcer in double-blind, randomized fashion either (1) placebo at 6 p."5.06A comparison of the effects on intragastric acidity of bedtime or dinnertime administration of a once daily dose of famotidine. ( Celle, G; Fera, G; Mela, GS; Savarino, V; Scalabrini, P; Sumberaz, A; Zentilin, P, 1988)
"Three double blind crossover studies were carried out to assess the ability of primed infusions of famotidine to raise intragastric pH over 24 hours in 12 duodenal ulcer patients."5.06Continuous intravenous infusions of famotidine maintain high intragastric pH in duodenal ulcer. ( Kaufman, D; Kempf, M; Merki, HS; Neumann, J; Röhmel, J; Walt, RP; Witzel, L, 1988)
"In 11 duodenal ulcer patients, the antisecretory effects of bedtime famotidine 40 mg were compared to those obtained with ranitidine 300 mg and placebo by means of continuous 24-hour intragastric pH monitoring."5.06Continuous 24-hour intragastric pH monitoring in the evaluation of the effect of a nightly dose of famotidine, ranitidine and placebo on gastric acidity of patients with duodenal ulcer. ( Celle, G; Di Timoteo, E; Magnolia, MR; Mela, GS; Savarino, V; Scalabrini, P, 1987)
"185 patients with endoscopically proven duodenal ulcers were randomly allocated to treatment with either famotidine 40 mg nocte, 20 mg bid, 40 mg bid or ranitidine 150 mg bid for 2-8 weeks in a prospective double-blind study."5.05[Famotidine versus ranitidine in the acute treatment of duodenal ulcer. A multicenter comparative study in Germany]. ( Dammann, HG; Jakob, G; Miederer, SE; Müller, P; Ottenjann, R; Paul, F; Scholten, T; Schütz, E; Seifert, E; Simon, B, 1985)
"One-hundred and eight-three patients with endoscopically proven duodenal ulcers, enrolled in this prospective, double-blind study, were randomly allocated to receive famotidine 40 mg once at night, 20 mg twice daily, 40 mg twice daily, or ranitidine 150 mg twice daily for 2-8 weeks."5.05Famotidine versus ranitidine for the short-term treatment of duodenal ulcer. ( Dammann, HG; Jakob, G; Miederer, SE; Müller, P; Ottenjann, R; Paul, F; Scholten, T; Schütz, E; Seifert, E; Simon, B, 1985)
"The new H2 receptor antagonist, famotidine, has been tested in open and double-blind studies in over 2,000 acute duodenal or gastric ulcer patients as well as in the maintenance of chronic duodenal ulcer patients."5.05Famotidine in the treatment of gastric and duodenal ulceration: overview of clinical experience. ( Bianchi Porro, G, 1985)
"The aim of this study was to gain experience concerning efficacy and safety of famotidine, the new H2-receptor antagonist, for the maintenance of duodenal ulcer disease."5.05[Famotidine versus placebo in prevention of the recurrence of duodenal ulcer disease. A multicenter study in Germany, Austria and Italy]. ( Baglioni, A; Barbara, L; Bianchi-Porro, G; Blasi, A; Canelli, B; Cheli, R; Dal Monte, R; Dammann, HG; Francavilla, A; Hentschel, E, 1985)
"Although anti-inflammatory doses of ibuprofen are very effective in treating the signs and symptoms of osteoarthritis (OA), they come with an increased risk for gastrointestinal damage which can limit their use and decrease patient adherence to therapy."4.90Risk of upper gastrointestinal ulcers in patients with osteoarthritis receiving single-tablet ibuprofen/famotidine versus ibuprofen alone: pooled efficacy and safety analyses of two randomized, double-blind, comparison trials. ( Bello, AE; Grahn, AY; Holt, RJ; Kent, JD; Rice, P, 2014)
" Early indications that acid suppression was effective in the management of NSAID-related peptic ulcers came from studies showing that gastric ulcers could be healed by omeprazole in patients who continued to take NSAIDs."4.80Management of nonsteroidal anti-inflammatory drug-induced gastroduodenal disease by acid suppression. ( Armstrong, D; Lad, R, 1999)
"The aim was to compare the clinical efficacy of lansoprazole with the efficacies of ranitidine and famotidine in order to rank this drug in the hierarchy of duodenal ulcer treatments."4.79Meta-analysis of randomized clinical trials comparing lansoprazole with ranitidine or famotidine in the treatment of acute duodenal ulcer. ( Agostini, H; Lemaire, M; Poynard, T, 1995)
"The clinical efficacy of famotidine has been clearly shown in the short- and long-term treatment of a number of acid-related diseases such as duodenal and gastric ulcer as well as in the acute management of reflux esophagitis."4.78Clinical efficacy of famotidine in the treatment of acid-related diseases: an overview. ( Dammann, HG, 1990)
"The FDA has approved Duexis (Horizon), a fixed-dose combination of the nonsteroidal anti-inflammatory drug (NSAID) ibuprofen and the H2-receptor antagonist (H2RA) famotidine, for symptomatic relief of osteoarthritis and rheumatoid arthritis and to decrease the risk of developing gastric and duodenal ulcers in patients at risk for NSAID-associated ulcers."3.77A fixed-dose combination ibuprofen and famotidine (Duexis). ( , 2011)
"To study the effects of growth factors on experimental duodenal ulcer healing in indomethacin-treated rats."3.72Effect of exogenous administration of transforming growth factor-beta and famotidine on the healing of duodenal ulcer under the impact of indomethacin. ( Arceiz, E; Lanas, A; Ortego, J; Pérez-Aisa, A; Sainz, R; Sopeña, F, 2003)
"Duodenal ulcer was induced in male Wistar rats with acetic acid."3.71[Effect of exogenous administration of platelet-derived growth factor and epidermal growth factor on duodenal ulcer healing in rats treated with indomethacin]. ( Arceiz Gonzalo, E; Lanas Arbeloa, A; Ortego Díez De Retana, J; Pérez Aisa, A; Sainz Samitier, R; Sopeña Biarge, F, 2002)
" pylori-infected patients with duodenal ulcer were treated with either omeprazole or famotidine plus two antibiotics for 2 wk."3.70The long-term reinfection rate and the course of duodenal ulcer disease after eradication of Helicobacter pylori in a developing country. ( Acevedo, C; Duarte, I; Figueroa, C; Fuster, F; Giancaspero, R; Hola, K; Rollan, A; Schulz, M, 2000)
"24-h monitoring of pH of the gastric juice demonstrated that three-component therapy consisting of quamatel (20 mg/day, metronidazole (500 mg 4 times a day), amoxicillin (750 mg 3 times a day) maintains the level of intragastric acidity optimal for quick scarring of duodenal ulcer defect and led to eradication of H."3.70[24-hour monitoring of gastric juice pH in assessment of anti-ulcer treatment]. ( Andreev, NG; Ismailova, MZ; Maev, IV; Romashkina, MA; Val'tsova, ED, 2000)
") inhibited mepirizole-induced duodenal ulcers."3.69YM022 [(R)-1-[2,3-dihydro-1-(2'-methylphenacyl)-2-oxo-5-phenyl- 1H-1,4-benzodiazepin-3-yl]-3-(3-methylphenyl)urea], a potent and selective gastrin/cholecystokinin-B receptor antagonist, prevents gastric and duodenal lesions in rats. ( Akuzawa, S; Ito, H; Kamato, T; Kobayashi, A; Miyata, K; Nagakura, Y; Nishida, A; Takinami, Y; Yamano, M; Yuki, H, 1994)
"The gastrojet, a closed loop pH feedback infusion pump capable of maintaining intragastric pH at a target value by infusing H2 blockers at variable rates, was used to assess factors influencing the quantity of famotidine required to maintain intragastric pH above 4 for 24 hours in 34 fed patients with duodenal ulcers."3.69Maintenance of intragastric pH > 4 with famotidine in duodenal ulcer patients: factors influencing drug requirements. ( Deharvengt, MC; Delchier, JC; Elouaer Blanc, L; Roudot-Thoraval, F; Stanescu, L, 1994)
"A 51-year-old obese woman with a duodenal ulcer developed symptomatic, famotidine-induced hepatitis."3.69Hepatitis following treatments with famotidine and then cimetidine. ( Davis, RL; Egli, D; Hashimoto, F, 1994)
"The combination of sucralfate (SUC) and famotidine (FAM) at subtherapeutic dose on cysteamine-induced duodenal ulcers (3 x 250 mg/kg) in female rats was studied."3.69The effect of the combination therapy with sucralfate and famotidine on experimentally induced duodenal ulcers in rats. ( Zupancic, P, 1996)
"Healing-promoting actions of KU-1257 (N-ethyl-N'-[3-[3-(piperidinomethyl)phenoxy]propyl]urea, CAS 120958-90-9) were investigated in chronic gastric and duodenal ulcer models induced by acetic acid in rats and the effects were compared with those of famotidine and roxatidine acetate by gross or histological evaluation."3.68Healing-promoting action of the new histamine H2-receptor antagonist N-ethyl-N'-[3-[3-(piperidinomethyl)phenoxy]propyl]urea with dual action on chronic gastric and duodenal ulcers induced by acetic acid in rats. ( Aijima, H; Hamada, K; Nishino, K; Sekiguchi, H; Taga, F; Uchida, H, 1993)
"The studies of microsomal liver enzyme activity by means of a respiratory test with 14C-aminopyrine (ABT) were carried out in 20 patients with duodenal ulcer treated for eight weeks with famotidine."3.68[Evaluation of microsomal enzyme function in the liver in patients with duodenal ulcer treated with famotidine]. ( Grzeszczak, W; Piotrowska, E; Piotrowski, J, 1993)
"The liver microsomal enzymes activity was measured by aminopyrine breath test in 20 subjects with duodenal ulcer disease treated with famotidine for 8 weeks."3.68[Assessment of microsomal enzyme function in liver of patients with duodenal ulcer treated with famotidine]. ( Grzeszczak, W; Piotrowska, E; Piotrowski, J, 1993)
"Fourteen patients with duodenal ulcers and eight healthy volunteers were examined to measure interdigestive gastroduodenal motility and plasma motilin."3.68Gastric acid inhibits antral phase III activity in duodenal ulcer patients. ( Horikoshi, T; Kawamura, O; Kikuchi, K; Kusano, M; Matsuzaki, T; Nishioka, T; Sekiguchi, T, 1993)
"In this open trial, 25 patients with identified duodenal ulcers were given long-term therapy of a single evening dose of 20 mg famotidine."3.68[Prevention of the recurrence of duodenal ulcer with famotidine. Report of experiences with long-term therapy in an open clinical study]. ( Judmaier, G, 1992)
" Gastric and duodenal ulcerations induced by cold stress plus indomethacin, restraint and water immersion stress, pylorus ligation or cysteamine were also inhibited by pretreatment with 2-B4O."3.68Effect of an endogenous satiety substance, 2-buten-4-olide, on gastric acid secretion and experimental ulceration in rats. ( Arai, I; Muramatsu, M; Oomura, Y; Otomo, S; Shiraishi, T; Usuki-Ito, C, 1990)
"Fifty three patients with duodenal ulcer were treated with 40 mg of famotidine at bed time."3.67A single nocte dose of famotidine in the treatment of duodenal ulcer. ( Ahmad, W; Qureshi, H; Zuberi, SJ, 1989)
"The aim of this study was to evaluate the clinical efficacy of short and long-term treatment with famotidine 40 mg/daily at bed time in duodenal ulcer disease."3.67[Famotidine in the short and long term treatment of duodenal ulcer: clinical and physiopathologic study]. ( Dal Santo, L; Di Mario, F; Gottardello, L; Grassi, SA; Naccarato, R; Pasqualetti, P; Tessaro, P; Vianello, F; Vio, A, 1989)
"1 The effects of the new H2-receptor antagonist famotidine, administered orally, on gastric secretion and emptying as well as on experimentally-induced gastric and duodenal ulcers were studied in the rat."3.67Antisecretory and antiulcer effect of the H2-receptor antagonist famotidine in the rat: comparison with ranitidine. ( Scarpignato, C; Tramacere, R; Zappia, L, 1987)
"The H2-receptor antagonists mifentidine, famotidine, cimetidine and ranitidine were examined for their ability to prevent the duodenal ulcer caused by mepirizole (250 mg/kg p."3.67Effect of mifentidine on mepirizole-induced duodenal ulcer in the rat. ( Brambilla, A; De Paoli, AM; Ghiorzi, A; Giachetti, A, 1987)
"Data from several sources are used to quantify the expected direct medical costs of a recently healed duodenal ulcer patient prescribed an H2-antagonist (famotidine) for a 6-month period."3.67The cost-effectiveness of maintenance therapy for duodenal ulceration with an H2-antagonist. ( Fox, N; Jacobs, J; Morton, RE, 1988)
"The effect of a single bedtime dose of famotidine 40 mg on gonadal function was studied in 8 male duodenal ulcer patients."3.67Famotidine has no significant effect on gonadal function in man. ( Bessarione, D; Celle, G; Giusti, M; Magnolia, MR; Percario, G; Savarino, V; Scalabrini, P, 1988)
"Healing processes of duodenal ulcers induced by mepirizole and effects of several drugs on the ulcer healing were studied in rats."3.66Effects of antiulcer agents on healing of mepirizole-induced duodenal ulcers in rats. ( Ishihara, Y; Okabe, S, 1983)
"Famotidine was administered after lunch and before sleep, and the others were after breakfast and dinner."2.71Concomitant dosing of famotidine with a triple therapy increases the cure rates of Helicobacter pylori infections in patients with the homozygous extensive metabolizer genotype of CYP2C19. ( Furuta, T; Miura, S; Okudaira, K; Shirai, N; Sugimoto, M, 2005)
"Famotidine increased the lower esophagus sphincter pressure from the initial 2."2.68[The effect of cimetidine and famotidine on esophageal motility]. ( Paradowski, L; Salomon, A; Szelag, A, 1996)
"for the prevention of duodenal ulcer recurrence."2.67A controlled study of 20 mg famotidine nocte vs. 150 mg ranitidine nocte for the prevention of duodenal ulcer relapse. ( Barbara, L; Bianchi Porro, G; Blasi, A; Bovero, E; Capurso, L; Cheli, R; Corinaldesi, R; Koch, M; Lazzaroni, M; Mangiameli, A, 1991)
"Famotidine appears to be an effective and safe once-a-day therapy for the treatment of acute duodenal ulcer disease."2.66A multicenter, double-blind, randomized, placebo-controlled comparison of nocturnal and twice-a-day famotidine in the treatment of active duodenal ulcer disease. ( Berman, R; Gitlin, N; Mantell, G; McCullough, AJ; Smith, JL, 1987)
" In view of possible increased patient compliance with a simplified dosage regimen, famotidine 40 mg h."2.66Review of an extensive worldwide study of a new H2-receptor antagonist, famotidine, as compared to ranitidine in the treatment of acute duodenal ulcer. ( Bianchi Porro, G; Cook, T; Dicenta, C; Humphries, TJ, 1987)
"H2-blockers reduce the annual recurrence from nearly 70% to about 25%."2.66H2-receptor antagonists and duodenal ulcer recurrence: analysis of efficacy and commentary on safety, costs, and patient selection. ( Freston, JW, 1987)
" Therefore, the two dosing schedules of each H2 antagonist increased intragastric pH differently, but both the half and the standard large regimens produced similar overnight virtual anacidity."2.66Overnight comparable anacidity by standard large and half-single bedtime doses of H2 antagonists in duodenal ulcer patients: a clinical pharmacological study. ( Celle, G; Fera, G; Mela, GS; Savarino, V; Scalabrini, P; Sumberaz, A; Zentilin, P, 1988)
"Ibuprofen/famotidine was generally well tolerated, with a tolerability profile consistent with those established for the individual agents."2.49Fixed-dose ibuprofen/famotidine: a review of its use to reduce the risk of gastric and duodenal ulcers in patients requiring NSAID therapy. ( Deeks, ED, 2013)
" This study was undertaken to determine whether patients with chronic use of H2-receptor antagonists (HRA) had demonstrable decreases in bone mineral density (BMD)."1.30Bone mineral density in patients taking H2-receptor antagonist. ( Adachi, Y; Iso, Y; Kitano, S; Matsumata, T; Shiota, E; Yoh, R, 1998)
"93 patients (19%) were treated for abdominal pain where no diagnosis had been reached or who had only a diagnosis of gastritis on endoscopy."1.29Long term acid suppressing treatment in general practice. ( Jacyna, MR; Levi, AJ; Miller, RJ; O'Reilly, S; Ross, J; Ryder, SD, 1994)
"None of these 15 patients had a recurrence 3 months later."1.28The histological maturity of regenerating mucosa of healed duodenal ulcer and ulcer recurrence after treatment with H2-antagonist. ( Liao, CH; Pan, S, 1990)
"Operative management also reduces recurrence rates, which, however, are commoner in patients coming to surgery nowadays."1.28High doses of ranitidine in maintenance therapy of duodenal ulcer patients. ( Lee, FI, 1990)
" The therapy was prolonged for two years with the same dosage at the beginning and later with half doses without any relapse and secondary effects."1.28[Duodenal ulcer, study of gastric secretion and rational treatment with famotidine in different doses]. ( Idotta, G; Morucci, P; Santoro, E; Scutari, F, 1989)
"Famotidine is a potent H2 receptor antagonist containing a thiazole ring structure, thus differing chemically from cimetidine and ranitidine."1.27Famotidine. The ACG Committee on FDA-Related Matters with primary authorship by G. Friedman. American College of Gastroenterology. ( , 1987)
" The expected antisecretory effect of a particular dosage regimen in patients with duodenal ulcer can be predicted mathematically from data derived from studies in normal volunteers."1.27Comparison of the effects of gastric antisecretory agents in healthy volunteers and patients with duodenal ulcer. ( Burget, DW; Howden, CW; Hunt, RH; Jones, DB, 1986)

Research

Studies (169)

TimeframeStudies, this research(%)All Research%
pre-199066 (39.05)18.7374
1990's72 (42.60)18.2507
2000's23 (13.61)29.6817
2010's7 (4.14)24.3611
2020's1 (0.59)2.80

Authors

AuthorsStudies
Wong, GLH1
Lau, LHS1
Ching, JYL1
Tse, YK1
Ling, RHY1
Wong, VWS1
Chiu, PWY1
Lau, JYW1
Chan, FKL1
Deeks, ED1
Nichitaĭlo, ME1
Bello, AE3
Kent, JD2
Grahn, AY2
Rice, P1
Holt, RJ2
Laine, L1
Kivitz, AJ1
Schiff, MH1
Taha, AS3
Chan, FK1
Grinevich, VB2
Uspenskiĭ, IuP1
Shabanova, GZh1
Sablin, OA2
Shcherbina, NN1
Uspenskiĭ, IuL1
Ohsawa, T1
Hirata, W1
Higichi, S1
Pérez-Aisa, A1
Sopeña, F1
Arceiz, E1
Ortego, J1
Sainz, R1
Lanas, A1
Kirika, NV1
Bodrug, NI1
Butorov, IV1
Butorov, SI1
Korukov, B1
Ognianov, S1
Kostadinova, R1
Gerzilov, P1
Ivanov, A1
Iarŭmov, N1
Okudaira, K1
Furuta, T1
Shirai, N1
Sugimoto, M1
Miura, S1
Guseĭnzade, MG1
Vakhrushev, IaM2
Muravtseva, OV2
Ji, F1
Chen, JY1
Chen, JX1
Ishihara, Y1
Okabe, S1
Shiratori, K1
Watanabe, S1
Maruyama, M1
Itoh, Y1
Adachi, H1
Kurokawa, K1
Takeuchi, T1
Mori, H1
Masci, E1
Colombo, E1
Testoni, PA1
Fanti, L1
Guslandi, M1
Tittobello, A1
Delchier, JC2
el Amine, I1
Roudot-Thoraval, F2
Elouaer-Blanc, L2
Lamarque, D1
Stanescu, L2
Maculotti, L1
Pradella, P1
Gschwantler, M2
Weiss, W4
Penka, G1
Zirm, B1
Stupnicki, T1
Spath, P1
Sobhani, I1
Chastang, C1
De Korwin, JD1
Lamouliatte, H1
Mégraud, F1
Guerre, J1
Dominguez, HL1
Freston, JW2
Arizón Deza, P1
García Tenorio, A1
Gonzalo Til, A1
Manero Ruiz, I1
Mur Lalueza, MJ1
Pascual Parrilla, MS1
Casini, A2
Mari, F2
Surrenti, C2
Lin, JT1
Wang, JT1
Wu, MS1
Lee, WY1
Yang, JC1
Wang, TH2
Nishida, A1
Takinami, Y1
Yuki, H1
Kobayashi, A1
Akuzawa, S1
Kamato, T1
Ito, H1
Yamano, M1
Nagakura, Y1
Miyata, K1
Matsunaga, Y1
Yamamoto, O1
Ueki, S1
Haga, N1
Mizusawa, F1
Mizumoto, A1
Sano, I1
Itoh, Z1
Deharvengt, MC1
Elouaer Blanc, L1
Sekiguchi, H1
Hamada, K1
Aijima, H1
Taga, F1
Uchida, H1
Nishino, K1
Hashimoto, F1
Davis, RL1
Egli, D1
Reynolds, JC3
Schoen, RE1
Maislin, G1
Zangari, GG1
Ryder, SD1
O'Reilly, S1
Miller, RJ1
Ross, J1
Jacyna, MR1
Levi, AJ1
Pizzigallo, AM1
Bertol, E1
Misra, SC1
Dasarathy, S1
Sharma, MP1
Piotrowska, E2
Piotrowski, J2
Grzeszczak, W2
Gabryelewicz, A1
Kosidło, S1
Marlicz, K1
Jaroszewicz-Heigelmann, H1
Kusano, M1
Sekiguchi, T1
Nishioka, T1
Kawamura, O1
Kikuchi, K1
Matsuzaki, T1
Horikoshi, T1
Poynard, T1
Lemaire, M1
Agostini, H1
Hudson, N2
Hawkey, CJ2
Swannell, AJ1
Trye, PN1
Cottrell, J3
Mann, SG3
Simon, TJ1
Sturrock, RD2
Russell, RI2
Zupancic, P1
Goh, KL1
Navaratnam, P1
Peh, SC1
Wong, NW1
Chuah, SY1
Rahman, NA1
Lo, YL1
Goenka, MK1
Kochhar, R1
Chakrabarti, A1
Kumar, A1
Gupta, O1
Talwar, P1
Mehta, SK1
Liss, GM1
Paradowski, L1
Salomon, A1
Szelag, A1
García-Plaza, A1
Arenas, JI1
Belda, O1
Diago, A1
Domínguez, A1
Fernández, C1
Martín, L1
Pallarés, A1
Rodrigo, L2
de la Santa, Jw1
Pal'tsev, AI1
Maslennikova, TA1
Trye, P1
Swanell, AJ1
Grigor'ev, PI1
Grinberg, AA1
Toguzova, DA2
Iakovenko, AV1
Lopatina, IV1
Suzuki, M1
Mori, M1
Miyayama, A1
Iwai, N1
Tsunematsu, N1
Oonuki, M1
Suzuki, H1
Hibi, T1
Ishii, H1
Adachi, Y1
Shiota, E1
Matsumata, T1
Iso, Y1
Yoh, R1
Kitano, S1
Malov, IuS1
Kulikov, AN1
Dogăn, UB1
Tunçer, C1
Dursun, A1
Kandilci, U1
Das, UN1
Sheptulin, AA1
Okhlobystin, AV1
Dragosics, B2
Wurzer, H1
Brandstätter, G1
Bogachev, RS1
Levina, ZK1
Kulkarni, SH1
Kshirsagar, AY1
Lad, R1
Armstrong, D1
Rollan, A1
Giancaspero, R1
Fuster, F1
Acevedo, C1
Figueroa, C1
Hola, K1
Schulz, M1
Duarte, I1
Maev, IV1
Andreev, NG1
Val'tsova, ED1
Romashkina, MA1
Ismailova, MZ1
Pleshkov, VG1
Afanas'ev, VN1
Ovsiankin, AV1
Mansurova, FKh1
Kadyrov, DM1
Odinaev, RI1
Ishankulova, DM1
Liu, WZ1
Xiao, SD1
Hu, PJ1
Lu, H1
Cui, Y1
Tytgat, GN1
Shlevkov, BA1
Abramova, LA1
Rakov, AL1
Makarov, IuS1
Gorbakov, VV1
Mironenko, DA1
Golochalova, TV1
Nikiforov, PA1
Bazarova, MA1
Nikitina, SA1
Osin, VL1
Shugurov, VA1
Mutoh, H1
Sugano, K1
Pérez Aisa, A1
Sopeña Biarge, F1
Arceiz Gonzalo, E1
Sainz Samitier, R1
Ortego Díez De Retana, J1
Lanas Arbeloa, A1
Sato, H1
Abe, K1
Oshima, N1
Kawashima, K1
Hamamoto, N1
Moritani, M1
Mak, R1
Ishihara, S1
Adachi, K1
Kawauchi, H1
Kinoshita, Y1
Tsimmerman, IaS1
Teliaper, II1
Ogawa, N1
Savarino, V10
Mela, GS8
Zentilin, P5
Cutela, P1
Mele, MR1
Celle, G9
Delle Fave, G1
Annibale, B1
Franceschi, M1
Quatrini, M1
Cassetta, MR1
Torsoli, A1
Kumar, TR1
Naidu, MU1
Shobha, JC1
Reddy, DN1
Subhash, S1
Chaubal, C1
Prasad, R1
Babu, S1
Judmaier, G1
Okulski, G1
Brunner, H1
Khasawneh, SM1
Affarah, HB1
Hotz, J1
Kleinert, R1
Grymbowski, T1
Hennig, U1
Schwarz, JA1
Okada, M1
Arita, M1
Iida, M1
Yao, T1
Sakurai, T1
Hoshiko, K1
Maeda, K1
Okada, Y1
Sakamoto, K1
Masoero, G1
Rossanino, A1
Arossa, W1
De la Pierre, M1
Fullarton, GM1
Macdonald, AM1
McColl, KE1
Bianchi Porro, G5
Lazzaroni, M3
Barbara, L4
Corinaldesi, R3
Blasi, A4
Mangiameli, A3
Capurso, L2
Koch, M2
Cheli, R4
Bovero, E3
White, C1
Smolensky, MH1
Sanders, SW1
Buchi, KN1
Moore, JG1
Inatomi, N1
Nagaya, H1
Takami, K1
Shino, A1
Satoh, H1
Collen, MJ2
Sheridan, MJ1
Lipsy, RJ1
Fennerty, B1
Fagan, TC1
Pan, S1
Liao, CH1
Akhtar, MA1
Rashid, P1
Khan, MA1
Thomson, AB2
Shibata, M1
Yamaura, T1
Sekine, A1
Nishikawa, M1
Chida, Y1
Ohnishi, H1
Sikiric, P1
Rotkvic, I1
Mise, S1
Petek, M1
Rucman, R1
Seiwerth, S1
Zjacic-Rotkvic, V1
Duvnjak, M1
Jagic, V1
Suchanek, E1
Sawant, PD1
Nanivadekar, SA1
Patel, HD1
Shroff, CP1
Oke, VG1
Jha, RJ1
Bowalekar, SK1
Navani, SR1
Raghu, CN1
Bussalleu, A1
Berrios, J1
Espejo, H1
Espinoza, R1
Farfán, G1
Galarza, J1
Guerra, J1
Nago, A1
Simich, C1
Valladares, G1
Dammann, HG6
Lee, FI2
Arai, I1
Usuki-Ito, C1
Muramatsu, M1
Otomo, S1
Shiraishi, T1
Oomura, Y1
Alcalá Santaella, R2
Guardia, J3
Pajares, J3
Piqué, J3
Pita, L3
Alvárez, E3
Castellanos, P3
Guarner, L3
Ortiz, J3
Pesquera, R3
Pinchbeck, BR1
Kirdeikis, J1
Zuk, L1
Marriage, B1
Prat, A1
Booth, SN1
Cochran, KM1
Crowe, J1
Dickinson, RJ1
Kennedy, NP1
Marenco, G2
Menardo, G1
Pallini, P1
Rossini, FP1
Saggioro, A1
Gitnick, G1
Chen, PH1
Wang, CY1
Chen, CY1
Cheng, TC1
Tsai, YT1
Siauw, CP1
Yang, KC1
Chen, GH1
Sung, JL1
Scalabrini, P7
Bonifacino, G1
Gambaro, P1
Qureshi, H2
Ahmad, W1
Zuberi, SJ2
Viver, J1
Conchillo, F1
Barrio, E1
Forné, M1
Zozaya, JM1
Alvarez, A1
Dieguez, P1
Muñoz, M1
Panés, J1
Alcalá-Santaella, R1
Delvaux, M1
Hagège, CG1
Ribet, A1
Vio, A1
Pasqualetti, P1
Gottardello, L1
Grassi, SA1
Vianello, F1
Dal Santo, L1
Tessaro, P1
Di Mario, F1
Naccarato, R1
Materia, A1
Genco, A1
Silecchia, G1
Basso, N1
Santoro, E1
Morucci, P1
Idotta, G1
Scutari, F1
Simon, B4
Jakob, G2
Miederer, SE2
Müller, P3
Ottenjann, R2
Paul, F2
Scholten, T2
Schütz, E2
Seifert, E2
Smith, JL2
Carratelli, L1
Wilkins, A1
Baglioni, A1
Bianchi-Porro, G1
Canelli, B1
Dal Monte, R1
Francavilla, A1
Hentschel, E1
Rohner, HG2
Gugler, R2
McCullough, AJ2
Texter, EC1
Navab, F1
Mantell, G2
Berman, R2
Gitlin, N2
Kimmig, JM2
Schönekäs, H2
Marks, IN1
Wright, JP1
Dicenta, C1
Cook, T1
Humphries, TJ1
Dobrilla, G1
De Pretis, G1
Piazzi, L1
Boero, A1
Camarri, E1
Crespi, M1
Fontana, G1
Ideo, G1
Manenti, F1
Scarpignato, C1
Tramacere, R1
Zappia, L1
Santana, IA1
Lanzon-Miller, S1
Pounder, RE1
Lezoche, E1
Vagni, V1
D'Alessandro, MD1
Mariani, P1
Carlei, F1
Lomanto, D1
Nardovino, M1
Martelli, A1
Speranza, V1
Picciotto, A1
Magnolia, MR3
Brambilla, A1
Ghiorzi, A1
De Paoli, AM1
Giachetti, A1
Sumberaz, A3
Fera, G3
Pounder, R1
Fiorucci, S1
Clausi, GG1
Farinelli, M1
Santucci, L1
Farroni, F1
Pelli, MA1
Morelli, A1
Bonardelli, P1
Fujita, Y1
Fujita, R1
Sugata, F1
Fox, N1
Morton, RE1
Jacobs, J1
Stanczak, VJ1
Ciarleglio, CA1
Reggio, D1
Frattaroli, FM1
Trentino, P1
Oddi, A1
Marzullo, A1
Ponsioen, C1
Pappalardo, G1
Hartmann, H1
Fölsch, UR1
Zaterka, S1
de Paula Castro, L1
Villalobos, JJ1
Massuda, HK1
Eisig, JN1
Dias Avelar, C1
Coelho, LG1
Bettarello, A1
Giusti, M1
Bessarione, D1
Percario, G1
Ahmed, W1
Merki, HS1
Witzel, L1
Kaufman, D1
Kempf, M1
Neumann, J1
Röhmel, J1
Walt, RP1
Di Timoteo, E1
Polloni, A1
Marchi, S1
Greco, A1
Cipparrone, G1
Costa, F1
Bellini, M1
Maltinti, G1
Lewis, JH1
Walter, TA1
Mueller, P1
Howden, CW1
Jones, DB1
Burget, DW1
Hunt, RH1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prevention of Recurrent Idiopathic Gastroduodenal Ulcer Bleeding: a Double-blind Randomized Trial[NCT01180179]Phase 4228 participants (Actual)Interventional2010-06-30Completed
A Randomized, Double-Blind, Phase 3 Study of the Efficacy and Safety of HZT-501 in Subjects Requiring NSAID Treatment[NCT00450658]Phase 3627 participants (Actual)Interventional2007-03-31Completed
A Randomized, Double-Blind, Phase 3 Study of the Efficacy and Safety of HZT-501 in Subjects Requiring NSAID Treatment[NCT00450216]Phase 3906 participants (Actual)Interventional2007-03-31Completed
The Phase 2 Study of FP-10, the Food Ingredient Derived From Milk Casein, on the Eradication Rates of Helicobacter Pylori by a Triple Therapy With Lansoprazole, Amoxicillin, and Clarithromycin[NCT00281047]Phase 2/Phase 3138 participants Interventional2006-01-31Recruiting
Efficacy of H2 Receptor Antagonist in Prevention of Thienopyridine-related Peptic Ulcer[NCT02418312]228 participants (Actual)Interventional2012-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Subjects Who Develop Endoscopically-diagnosed Duodenal Ulcers During the 24-week Treatment Period.

The secondary efficacy endpoint was the number of subjects with duodenal ulcer at any time throughout the 24 weeks of treatment. An ulcer was defined as a mucosal break of at least 3 mm in diameter with unequivocal depth. A subject is considered to have completed the study if all scheduled assessments up through the Week 24 visit have been performed. (NCT00450658)
Timeframe: 24 weeks

Interventionparticipants (Number)
HZT-5013
Ibuprofen9

Number of Subjects Who Develop Endoscopically-diagnosed Gastric Ulcers During the 24-week Treatment Period.

The secondary efficacy endpoint was the number of subjects with gastric ulcer at any time throughout 24 weeks of treatment. An ulcer was defined as a mucosal break of at least 3 mm in diameter with unequivocal depth. A subject is considered to have completed the study if all scheduled assessments up through the Week 24 visit have been performed. (NCT00450658)
Timeframe: 24 weeks

Interventionparticipants (Number)
HZT-50137
Ibuprofen34

Number of Subjects Who Develop Endoscopically-diagnosed Upper Gastrointestinal Ulcers Confirmed by Endoscopy.

The primary efficacy endpoint was the number of subjects with upper gastrointestinal (i.e., gastric and/or duodenal) ulcer at any time throughout 24 weeks of treatment. An ulcer was defined as a mucosal break of at least 3 mm in diameter with unequivocal depth. A subject is considered to have completed the study if all scheduled assessments up through the Week 24 visit have been performed. (NCT00450658)
Timeframe: 24 weeks

Interventionparticipants (Number)
HZT-50140
Ibuprofen38

The Incidence Rate of NSAID-associated Serious Gastrointestinal Complications.

The secondary efficacy endpoint was the number of subjects developing a NSAID-associated serious GI complication at any time throughout 6 months of treatment. A NSAID-associated serious GI complication was defined as a perforation of ulcers, gastric outlet obstruction due to ulcers, and/or GI bleeding. (NCT00450658)
Timeframe: 24 weeks

Interventionparticipants (Number)
HZT-5010
Ibuprofen0

Number of Participants Who Develop Endoscopically-diagnosed Duodenal Ulcers During the 24-week Treatment Period.

The secondary efficacy endpoint was the number of participants with duodenal ulcer at any time throughout 24 weeks of treatment. An ulcer was defined as a mucosal break of at least 3 mm in diameter with unequivocal depth. A participant is considered to have completed the study if all scheduled assessments up through the Week 24 visit have been performed. (NCT00450216)
Timeframe: 24 weeks

Interventionparticipants (Number)
HZT-5018
Ibuprofen14

Number of Participants Who Develop Endoscopically-diagnosed Gastric Ulcers

The primary efficacy endpoint was the number of participants with gastric ulcer at any time throughout 24 weeks of treatment. An ulcer was defined as a mucosal break of at least 3 mm in diameter with unequivocal depth. A participant is considered to have completed the study if all scheduled assessments up through the Week 24 visit have been performed. (NCT00450216)
Timeframe: 24 weeks

Interventionparticipants (Number)
HZT-50155
Ibuprofen52

Number of Participants Who Develop Endoscopically-diagnosed Upper Gastrointestinal (UGI) Ulcers During the 24-week Treatment Period.

The secondary efficacy endpoint was the number of participants with UGI (i.e., gastric and/or duodenal) ulcer at any time throughout 24 weeks of treatment. An ulcer was defined as a mucosal break of at least 3 mm in diameter with unequivocal depth. A participant is considered to have completed the study if all scheduled assessments up through the Week 24 visit have been performed. (NCT00450216)
Timeframe: 24 weeks

Interventionparticipants (Number)
HZT-50163
Ibuprofen61

The Number of Participants Developing Non-steroidal Anti-inflammatory (NSAID)Associated Serious Gastrointestinal Complications (Perforation of Ulcers, Gastric Outlet Obstruction Due to Ulcers, Gastrointestinal Bleeding)

The secondary efficacy endpoint was the number of participants developing a NSAID-associated serious gastrointestinal complication at any time throughout 24 weeks of treatment. A NSAID-associated serious gastrointestinal complication was defined as a perforation of ulcers, gastric outlet obstruction due to ulcers, and/or gastrointestinal bleeding. (NCT00450216)
Timeframe: 24 weeks

Interventionparticpants (Number)
HZT-5013
Ibuprofen0

Number of Participants With Healed Peptic Ulcer

Follow-up endoscopy was performed at the end of the 6th month (NCT02418312)
Timeframe: 6 months

Interventionparticipants (Number)
Histamine-2 Receptor Antagonist Group106
Placebo Group101

Reviews

12 reviews available for famotidine and Curling Ulcer

ArticleYear
Fixed-dose ibuprofen/famotidine: a review of its use to reduce the risk of gastric and duodenal ulcers in patients requiring NSAID therapy.
    Clinical drug investigation, 2013, Volume: 33, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Combinations; Drug Interactions; Duodenal Ulcer; Famot

2013
Risk of upper gastrointestinal ulcers in patients with osteoarthritis receiving single-tablet ibuprofen/famotidine versus ibuprofen alone: pooled efficacy and safety analyses of two randomized, double-blind, comparison trials.
    Postgraduate medicine, 2014, Volume: 126, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Drug Combinations; Duodenal Ulcer; Famot

2014
Meta-analysis of randomized clinical trials comparing lansoprazole with ranitidine or famotidine in the treatment of acute duodenal ulcer.
    European journal of gastroenterology & hepatology, 1995, Volume: 7, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acute Disease; Anti-Ulcer Agents; Duodenal Ulcer; Famotidin

1995
Hypothesis: cis-unsaturated fatty acids as potential anti-peptic ulcer drugs.
    Prostaglandins, leukotrienes, and essential fatty acids, 1998, Volume: 58, Issue:5

    Topics: Anti-Ulcer Agents; Duodenal Ulcer; Famotidine; Fatty Acids, Unsaturated; Helicobacter Infections; He

1998
Management of nonsteroidal anti-inflammatory drug-induced gastroduodenal disease by acid suppression.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 1999, Volume: 13, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Duodenal Ulcer; Famotidine; Gastric Juic

1999
[Duodenal ulcer].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 1

    Topics: Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Duodenal Ulcer; Famotidine;

2002
[Effectiveness of ulcer treatment with electromagnetic radiation of extremely high frequency (EHF therapy) and some mechanism of its therapeutic action].
    Klinicheskaia meditsina, 2002, Volume: 80, Issue:5

    Topics: Anti-Ulcer Agents; Clinical Trials as Topic; Duodenal Ulcer; Electromagnetic Phenomena; Famotidine;

2002
Clinical review of histamine2 receptor antagonists.
    Archives of internal medicine, 1990, Volume: 150, Issue:4

    Topics: Cimetidine; Drug Interactions; Duodenal Ulcer; Famotidine; Histamine H2 Antagonists; Humans; Nizatid

1990
Acid secretion and acid suppression in pathogenesis and healing of peptic ulcer disease.
    Hepato-gastroenterology, 1990, Volume: 37 Suppl 1

    Topics: Anti-Ulcer Agents; Clinical Trials as Topic; Duodenal Ulcer; Famotidine; Gastric Acid; Histamine H2

1990
Clinical efficacy of famotidine in the treatment of acid-related diseases: an overview.
    Hepato-gastroenterology, 1990, Volume: 37 Suppl 1

    Topics: Clinical Trials as Topic; Duodenal Ulcer; Esophagitis, Peptic; Famotidine; Humans; Product Surveilla

1990
Famotidine in the USA: a review of efficacy studies.
    The Journal of international medical research, 1989, Volume: 17 Suppl 1

    Topics: Anti-Ulcer Agents; Duodenal Ulcer; Famotidine; Gastric Acid; Gastric Juice; Histamine H2 Antagonists

1989
Histamine H2-receptor antagonists.
    Bailliere's clinical gastroenterology, 1988, Volume: 2, Issue:3

    Topics: Animals; Clinical Trials as Topic; Duodenal Ulcer; Esophagitis, Peptic; Famotidine; Histamine H2 Ant

1988

Trials

91 trials available for famotidine and Curling Ulcer

ArticleYear
Prevention of recurrent idiopathic gastroduodenal ulcer bleeding: a double-blind, randomised trial.
    Gut, 2020, Volume: 69, Issue:4

    Topics: Aged; Aged, 80 and over; Double-Blind Method; Duodenal Ulcer; Famotidine; Female; Histamine H2 Antag

2020
Gastroprotective efficacy and safety of single-tablet ibuprofen/famotidine vs ibuprofen in older persons.
    The Physician and sportsmedicine, 2015, Volume: 43, Issue:3

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Age

2015
Gastroprotective efficacy and safety of single-tablet ibuprofen/famotidine vs ibuprofen in older persons.
    The Physician and sportsmedicine, 2015, Volume: 43, Issue:3

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Age

2015
Gastroprotective efficacy and safety of single-tablet ibuprofen/famotidine vs ibuprofen in older persons.
    The Physician and sportsmedicine, 2015, Volume: 43, Issue:3

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Age

2015
Gastroprotective efficacy and safety of single-tablet ibuprofen/famotidine vs ibuprofen in older persons.
    The Physician and sportsmedicine, 2015, Volume: 43, Issue:3

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Age

2015
Double-blind randomized trials of single-tablet ibuprofen/high-dose famotidine vs. ibuprofen alone for reduction of gastric and duodenal ulcers.
    The American journal of gastroenterology, 2012, Volume: 107, Issue:3

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-

2012
[Acid-base blood balance in patients with ulcer under treatment by the gastric secretion inhibitors and antacids].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2002, Issue:4

    Topics: Acid-Base Equilibrium; Adolescent; Adult; Aluminum Compounds; Antacids; Duodenal Ulcer; Famotidine;

2002
[Efficacy of different schemes of anti-helicobacter therapy in duodenal ulcer].
    Terapevticheskii arkhiv, 2004, Volume: 76, Issue:2

    Topics: Adult; Anti-Infective Agents; Anti-Ulcer Agents; Clarithromycin; Drug Administration Schedule; Drug

2004
[Study on the efficacy of famotidine (Quamatel) in the complex treatment of erosive gastroduodenitis, stress stomach ulcer and peptic duodenal ulcer].
    Khirurgiia, 2004, Volume: 60, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Bulgaria; Duodenal Ulcer; Famotidine; Female; Gas

2004
Concomitant dosing of famotidine with a triple therapy increases the cure rates of Helicobacter pylori infections in patients with the homozygous extensive metabolizer genotype of CYP2C19.
    Alimentary pharmacology & therapeutics, 2005, Feb-15, Volume: 21, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP

2005
[Comparative study on Jinghua Weikang Capsule and famotidine in treating duodenal ulcer].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2006, Volume: 26, Issue:4

    Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Drug Therapy, Combination; Drugs, Chinese Herbal; Duoden

2006
Colloid bismuth versus famotidine in the treatment and prevention of duodenal ulcer relapse: results of a double-blind, double dummy randomized study.
    Fundamental & clinical pharmacology, 1995, Volume: 9, Issue:3

    Topics: Antacids; Anti-Ulcer Agents; Bismuth; Colloids; Double-Blind Method; Duodenal Ulcer; Endoscopy, Gast

1995
Maintenance of gastric pH above 6 with intravenous famotidine in patients with a bleeding duodenal ulcer.
    Alimentary pharmacology & therapeutics, 1995, Volume: 9, Issue:2

    Topics: Adult; Aged; Duodenal Ulcer; Famotidine; Female; Gastric Acid; Humans; Hydrogen-Ion Concentration; I

1995
[Comparison between ranitidine, famotidine, and omeprazole in the treatment of bleeding duodenal ulcer].
    Minerva chirurgica, 1995, Volume: 50, Issue:3

    Topics: Duodenal Ulcer; Famotidine; Humans; Omeprazole; Peptic Ulcer Hemorrhage; Ranitidine

1995
Eradication of Helicobacter pylori by a combination of amoxicillin and famotidine.
    The American journal of gastroenterology, 1995, Volume: 90, Issue:9

    Topics: Amoxicillin; Drug Therapy, Combination; Duodenal Ulcer; Famotidine; Female; Gastritis; Helicobacter

1995
Antibiotic versus maintenance therapy in the prevention of duodenal ulcer recurrence. Results of a multicentric double-blind randomized trial.
    Gastroenterologie clinique et biologique, 1995, Volume: 19, Issue:3

    Topics: Adult; Amoxicillin; Double-Blind Method; Drug Therapy, Combination; Duodenal Ulcer; Famotidine; Fema

1995
Prospective, randomized study of H2-blocker and triple therapy for duodenal ulcer treatment and the eradication of Helicobacter pylori.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 1994, Volume: 93, Issue:5

    Topics: Adult; Amoxicillin; Bismuth; Drug Therapy, Combination; Duodenal Ulcer; Famotidine; Female; Helicoba

1994
Risk factors for delayed healing of duodenal ulcers treated with famotidine and ranitidine.
    The American journal of gastroenterology, 1994, Volume: 89, Issue:4

    Topics: Double-Blind Method; Duodenal Ulcer; Famotidine; Female; Humans; Male; Middle Aged; Prospective Stud

1994
Prolonged bedtime treatment with H2-receptor antagonists (ranitidine and famotidine) does not affect blood alcohol levels after ethanol ingestion in male patients with duodenal ulcer.
    The American journal of gastroenterology, 1994, Volume: 89, Issue:5

    Topics: Adult; Alcohol Dehydrogenase; Duodenal Ulcer; Ethanol; Famotidine; Helicobacter Infections; Helicoba

1994
Omeprazole versus famotidine in the healing and relapse of duodenal ulcer.
    Alimentary pharmacology & therapeutics, 1993, Volume: 7, Issue:4

    Topics: Absenteeism; Adult; Analgesics; Antacids; Double-Blind Method; Duodenal Ulcer; Famotidine; Female; H

1993
[Clinical evaluation of one-year controlled studies of duodenal ulcer recurrence rate in patients treated with the preparation Ulfamid].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1993, Volume: 46, Issue:5-6

    Topics: Adult; Duodenal Ulcer; Famotidine; Female; Follow-Up Studies; Humans; Male; Recurrence

1993
Famotidine for the prevention of gastric and duodenal ulcers caused by nonsteroidal antiinflammatory drugs.
    The New England journal of medicine, 1996, May-30, Volume: 334, Issue:22

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthriti

1996
Helicobacter pylori eradication with short-term therapy leads to duodenal ulcer healing without the need for continued acid suppression therapy.
    European journal of gastroenterology & hepatology, 1996, Volume: 8, Issue:5

    Topics: Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Drug Therapy, Combination; Du

1996
Candida overgrowth after treatment of duodenal ulcer. A comparison of cimetidine, famotidine, and omeprazole.
    Journal of clinical gastroenterology, 1996, Volume: 23, Issue:1

    Topics: Adult; Anti-Ulcer Agents; Candidiasis; Cimetidine; Duodenal Diseases; Duodenal Ulcer; Famotidine; Fe

1996
[The effect of cimetidine and famotidine on esophageal motility].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1996, Volume: 51, Issue:14-18

    Topics: Adult; Cimetidine; Duodenal Ulcer; Esophagus; Famotidine; Female; Gastroesophageal Reflux; Histamine

1996
[A multicenter clinical trial. Zinc acexamate versus famotidine in the treatment of acute duodenal ulcer. Study Group of Zinc acexamate (new UP doses)].
    Revista espanola de enfermedades digestivas, 1996, Volume: 88, Issue:11

    Topics: Acute Disease; Adult; Aged; Aminocaproates; Aminocaproic Acid; Anti-Ulcer Agents; Double-Blind Metho

1996
Famotidine for healing and maintenance in nonsteroidal anti-inflammatory drug-associated gastroduodenal ulceration.
    Gastroenterology, 1997, Volume: 112, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Duodenal Ulcer; Famotidine;

1997
Eradication of Helicobacter pylori by a 1-week course of famotidine, amoxicillin and clarithromycin.
    European journal of gastroenterology & hepatology, 1998, Volume: 10, Issue:7

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Drug Therapy, Combination; Duodenal Ulcer; Famotidi

1998
A new quadruple therapy for Helicobacter pylori using tripotassium dicitrato bismuthate, furazolidone, josamycin and famotidine.
    Alimentary pharmacology & therapeutics, 2000, Volume: 14, Issue:11

    Topics: Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents, Local; Anti-Ulcer Agents; Drug Therapy, C

2000
[Comparative antisecretory activity of famotidine, omeprazole, and rabeprazole (pariet) in ulcer disease based on daily pH-monitoring].
    Voenno-meditsinskii zhurnal, 2001, Volume: 322, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Benzimidazoles; Duodenal Ulcer; F

2001
[Double-blind controlled-clinical trials of lansoprazole in the treatment of peptic ulcer].
    Nihon rinsho. Japanese journal of clinical medicine, 1992, Volume: 50, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Triphosphatases; Adolescent; Adult; Aged; Anti-Ul

1992
Duration of acid suppression in H2-antagonist nonresponders.
    Digestion, 1992, Volume: 51, Issue:4

    Topics: Drug Tolerance; Duodenal Ulcer; Famotidine; Female; Gastric Acid; Gastric Acidity Determination; His

1992
Omeprazole versus famotidine in the short-term treatment of duodenal ulcer disease.
    Alimentary pharmacology & therapeutics, 1992, Volume: 6, Issue:4

    Topics: Abdominal Pain; Adult; Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Double-Blind Metho

1992
Comparative study of omeprazole and famotidine in the treatment of duodenal ulcer.
    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 1992, Volume: 11, Issue:2

    Topics: Adolescent; Adult; Aged; Double-Blind Method; Duodenal Ulcer; Famotidine; Female; Humans; Male; Midd

1992
[Therapy of peptic ulcers with famotidine. Report of experiences with an open clinical study].
    Wiener medizinische Wochenschrift (1946), 1992, Volume: 142, Issue:18

    Topics: Adult; Aged; Aged, 80 and over; Chronic Disease; Dose-Response Relationship, Drug; Drug Administrati

1992
[Time of famotidine administration and healing of duodenal ulcer: is 18.00 o'clock of importance?].
    Wiener medizinische Wochenschrift (1946), 1992, Volume: 142, Issue:18

    Topics: Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Duodenal Ulcer;

1992
Morning versus evening dose: a comparison of three H2-receptor blockers in duodenal ulcer healing.
    The American journal of gastroenterology, 1992, Volume: 87, Issue:9

    Topics: Adult; Cimetidine; Drug Administration Schedule; Duodenal Ulcer; Famotidine; Humans; Male; Middle Ag

1992
Lansoprazole versus famotidine: efficacy and tolerance in the acute management of duodenal ulceration.
    Alimentary pharmacology & therapeutics, 1992, Volume: 6, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Ulcer Agents; Double-Blind Method; Duoden

1992
A comparative study of once-a-day morning and once-a-day bedtime administration of 40 mg famotidine in treating duodenal ulcers.
    Gastroenterologia Japonica, 1992, Volume: 27, Issue:2

    Topics: Adult; Drug Administration Schedule; Duodenal Ulcer; Famotidine; Female; Gastric Acidity Determinati

1992
Prolonged gastric pH monitoring in responder and nonresponder duodenal ulcer patients: response to placebo and to H2-blocker administration.
    Journal of clinical gastroenterology, 1991, Volume: 13, Issue:3

    Topics: Adult; Circadian Rhythm; Drug Resistance; Duodenal Ulcer; Famotidine; Female; Gastric Acidity Determ

1991
Rebound hypersecretion after H2-antagonist withdrawal--a comparative study with nizatidine, ranitidine and famotidine.
    Alimentary pharmacology & therapeutics, 1991, Volume: 5, Issue:4

    Topics: Adult; Aged; Duodenal Ulcer; Famotidine; Gastric Acid; Gastric Acidity Determination; Gastric Mucosa

1991
Famotidine vs ranitidine h.s. in acute duodenal ulcer. A multicentre endoscopic trial.
    The Italian journal of gastroenterology, 1991, Volume: 23, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Double-Blind Method; Duodenal Ulcer; Endoscopy, Gastrointest

1991
Day-night and individual differences in response to constant-rate ranitidine infusion.
    Chronobiology international, 1991, Volume: 8, Issue:1

    Topics: Adult; Analysis of Variance; Circadian Rhythm; Duodenal Ulcer; Famotidine; Gastric Acid; Humans; Inf

1991
A controlled study of 20 mg famotidine nocte vs. 150 mg ranitidine nocte for the prevention of duodenal ulcer relapse.
    Alimentary pharmacology & therapeutics, 1991, Volume: 5, Issue:2

    Topics: Adult; Aged; Double-Blind Method; Duodenal Ulcer; Famotidine; Female; Humans; Male; Middle Aged; Ran

1991
Treatment of acute duodenal ulcers with famotidine and its comparison with other H2 blockers.
    JPMA. The Journal of the Pakistan Medical Association, 1990, Volume: 40, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Aged; Duodenal Ulcer; Famotidine; Female; Histamine H2 Antagonists

1990
Continuous intragastric pH monitoring: a real progress in the assessment of antisecretory drugs.
    The Italian journal of gastroenterology, 1990, Volume: 22 Suppl 2

    Topics: Adult; Double-Blind Method; Duodenal Ulcer; Equipment Design; Famotidine; Female; Gastric Acid; Gast

1990
Dopamine agonists prevent duodenal ulcer relapse. A comparative study with famotidine and cimetidine.
    Digestive diseases and sciences, 1991, Volume: 36, Issue:7

    Topics: Adult; Aged; Amantadine; Bromocriptine; Cimetidine; Duodenal Ulcer; Famotidine; Female; Humans; Male

1991
Double-blind comparison of the safety and efficacy of famotidine with ranitidine in patients with endoscopically diagnosed peptic ulcer.
    The Journal of the Association of Physicians of India, 1990, Volume: 38 Suppl 1

    Topics: Adult; Double-Blind Method; Duodenal Ulcer; Famotidine; Female; Humans; India; Male; Ranitidine; Sto

1990
[Famotidine in the treatment of duodenal peptic ulcer].
    Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru, 1990, Volume: 10, Issue:1

    Topics: Adult; Duodenal Ulcer; Famotidine; Female; Humans; Male; Middle Aged; Peru

1990
A multicentre, randomized, double-blind study comparing nocte famotidine or ranitidine for the treatment of active duodenal ulceration.
    Alimentary pharmacology & therapeutics, 1989, Volume: 3, Issue:1

    Topics: Adult; Aged; Antacids; Double-Blind Method; Duodenal Ulcer; Famotidine; Female; Humans; Male; Middle

1989
A single night-time dose of famotidine is equivalent to ranitidine in decreasing 24-hour gastric acidity in asymptomatic duodenal ulcer subjects.
    Alimentary pharmacology & therapeutics, 1989, Volume: 3, Issue:2

    Topics: Adult; Double-Blind Method; Duodenal Ulcer; Famotidine; Gastric Acid; Gastric Acidity Determination;

1989
Single night-time doses of 40 mg famotidine or 800 mg cimetidine in the treatment of duodenal ulcer.
    Alimentary pharmacology & therapeutics, 1989, Volume: 3, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aluminum Hydroxide; Antacids; Cimetidine; Double-Blind M

1989
Comparison between single morning and bedtime doses of 40 mg famotidine for the treatment of duodenal ulcer.
    Alimentary pharmacology & therapeutics, 1989, Volume: 3, Issue:3

    Topics: Adolescent; Adult; Aged; Double-Blind Method; Drug Administration Schedule; Duodenal Ulcer; Famotidi

1989
Famotidine in the treatment of duodenal ulcers resistant to other histamine H2-receptor antagonists.
    The Journal of international medical research, 1989, Volume: 17 Suppl 1

    Topics: Adult; Aged; Anti-Ulcer Agents; Duodenal Ulcer; Famotidine; Female; Histamine H2 Antagonists; Humans

1989
Famotidine therapy for active duodenal ulcers. A multivariate analysis of factors affecting early healing.
    Annals of internal medicine, 1989, Jul-01, Volume: 111, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Duodenal

1989
Comparison of the effects of placebo, ranitidine, famotidine and nizatidine on intragastric acidity by means of continuous pH recording.
    Digestion, 1989, Volume: 42, Issue:1

    Topics: Adult; Circadian Rhythm; Double-Blind Method; Duodenal Ulcer; Famotidine; Female; Gastric Acid; Gast

1989
A multicenter, randomized, double-blind study comparing famotidine with cimetidine in the treatment of active duodenal ulcer disease.
    Digestion, 1989, Volume: 42, Issue:2

    Topics: Adult; Cimetidine; Double-Blind Method; Drug Administration Schedule; Duodenal Ulcer; Famotidine; Fe

1989
A multicenter, randomized, double-blind study comparing once-daily bedtime administration of famotidine and ranitidine in the short-term treatment of active duodenal ulcer.
    Hepato-gastroenterology, 1989, Volume: 36, Issue:3

    Topics: Adult; Anti-Ulcer Agents; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedul

1989
A multicenter, randomized, double-blind study comparing a daily bedtime administration of famotidine and ranitidine in short-term treatment of active duodenal ulcer.
    Digestion, 1989, Volume: 42, Issue:2

    Topics: Adult; Anti-Ulcer Agents; Double-Blind Method; Drug Administration Schedule; Duodenal Ulcer; Famotid

1989
[Comparative efficacy of famotidine and ranitidine in the treatment of acute-phase duodenal ulcer. A French comparative therapeutic trial].
    Gastroenterologie clinique et biologique, 1989, Volume: 13, Issue:12

    Topics: Acute Disease; Adolescent; Adult; Aged; Cicatrix; Clinical Trials as Topic; Double-Blind Method; Dru

1989
[Famotidine versus ranitidine in the acute treatment of duodenal ulcer. A multicenter comparative study in Germany].
    Zeitschrift fur Gastroenterologie, 1985, Volume: 23, Issue:2

    Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Me

1985
Famotidine in the management of duodenal ulcer: experience in Italy.
    Digestion, 1985, Volume: 32 Suppl 1

    Topics: Adult; Circadian Rhythm; Clinical Trials as Topic; Double-Blind Method; Duodenal Ulcer; Famotidine;

1985
Famotidine versus ranitidine for the short-term treatment of duodenal ulcer.
    Digestion, 1985, Volume: 32 Suppl 1

    Topics: Adolescent; Adult; Aged; Antacids; Clinical Trials as Topic; Dose-Response Relationship, Drug; Doubl

1985
Famotidine in the treatment of gastric and duodenal ulceration: overview of clinical experience.
    Digestion, 1985, Volume: 32 Suppl 1

    Topics: Acute Disease; Chronic Disease; Cimetidine; Circadian Rhythm; Clinical Trials as Topic; Double-Blind

1985
[Famotidine versus placebo in prevention of the recurrence of duodenal ulcer disease. A multicenter study in Germany, Austria and Italy].
    Zeitschrift fur Gastroenterologie, 1985, Volume: 23, Issue:12

    Topics: Adult; Austria; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Duodena

1985
Treatment of active duodenal ulcers with famotidine. A double-blind comparison with ranitidine.
    The American journal of medicine, 1986, Oct-24, Volume: 81, Issue:4B

    Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Duodenal Ulcer; Famotidine; Female; Hist

1986
A multicenter, randomized, double-blind study comparing famotidine with ranitidine in the treatment of active duodenal ulcer disease.
    The American journal of medicine, 1986, Oct-24, Volume: 81, Issue:4B

    Topics: Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Duod

1986
Maintenance therapy of duodenal ulcer with famotidine. A multicenter United States study.
    The American journal of medicine, 1986, Oct-24, Volume: 81, Issue:4B

    Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Duodenal U

1986
A multicenter, double-blind, randomized, placebo-controlled comparison of nocturnal and twice-a-day famotidine in the treatment of active duodenal ulcer disease.
    Gastroenterology, 1987, Volume: 92, Issue:1

    Topics: Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Duodenal Ulcer; Famotid

1987
Famotidine (Pepcid).
    The Medical letter on drugs and therapeutics, 1987, Feb-13, Volume: 29, Issue:733

    Topics: Clinical Trials as Topic; Duodenal Ulcer; Famotidine; Gastric Acid; Histamine H2 Antagonists; Humans

1987
[Comparison of famotidine and ranitidine in duodenal ulcer].
    Deutsche medizinische Wochenschrift (1946), 1987, Feb-27, Volume: 112, Issue:9

    Topics: Clinical Trials as Topic; Duodenal Ulcer; Famotidine; Histamine H2 Antagonists; Humans; Ranitidine;

1987
Comparison of famotidine 40 mg with ranitidine 300 mg at night in short-term duodenal ulcer healing. A South African multicentre study.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1987, Jul-04, Volume: 72, Issue:1

    Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Duodenal Ulcer; Famotidine; Female; Histamine

1987
Review of an extensive worldwide study of a new H2-receptor antagonist, famotidine, as compared to ranitidine in the treatment of acute duodenal ulcer.
    Journal of clinical gastroenterology, 1987, Volume: 9 Suppl 2

    Topics: Acute Disease; Adult; Antacids; Duodenal Ulcer; Famotidine; Female; Histamine H2 Antagonists; Humans

1987
Comparison of once-daily bedtime administration of famotidine and ranitidine in the short-term treatment of duodenal ulcer. A multicenter, double-blind, controlled study.
    Scandinavian journal of gastroenterology. Supplement, 1987, Volume: 134

    Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule

1987
Effect of oral famotidine on 24-hour intragastric acidity.
    Postgraduate medical journal, 1986, Volume: 62 Suppl 2

    Topics: Administration, Oral; Adult; Aged; Dose-Response Relationship, Drug; Drug Evaluation; Duodenal Ulcer

1986
H2-receptor antagonists and duodenal ulcer recurrence: analysis of efficacy and commentary on safety, costs, and patient selection.
    The American journal of gastroenterology, 1987, Volume: 82, Issue:12

    Topics: Cimetidine; Clinical Trials as Topic; Costs and Cost Analysis; Duodenal Ulcer; Famotidine; Histamine

1987
Action of famotidine and ranitidine on prostaglandin E2 (PGE2) content of fundic and duodenal mucosa in duodenal ulcer patients.
    Drugs under experimental and clinical research, 1987, Volume: 13, Issue:10

    Topics: Adult; Dinoprostone; Duodenal Ulcer; Famotidine; Female; Gastric Mucosa; Histamine H2 Antagonists; H

1987
Single bedtime dose of famotidine: assessment of its antisecretory action by 24-hour intragastric pH monitoring.
    Journal of clinical pharmacology, 1987, Volume: 27, Issue:10

    Topics: Adult; Drug Administration Schedule; Duodenal Ulcer; Famotidine; Female; Gastric Acid; Gastric Acidi

1987
Once and twice daily doses of H2 antagonists revisited, using continuous intragastric pH monitoring.
    Scandinavian journal of gastroenterology, 1988, Volume: 23, Issue:4

    Topics: Adult; Clinical Trials as Topic; Duodenal Ulcer; Famotidine; Female; Gastric Acid; Gastric Acidity D

1988
Overnight comparable anacidity by standard large and half-single bedtime doses of H2 antagonists in duodenal ulcer patients: a clinical pharmacological study.
    The American journal of gastroenterology, 1988, Volume: 83, Issue:9

    Topics: Adult; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Double-Blind Method; Duodenal Ulcer; Fam

1988
Histamine H2-receptor antagonists.
    Bailliere's clinical gastroenterology, 1988, Volume: 2, Issue:3

    Topics: Animals; Clinical Trials as Topic; Duodenal Ulcer; Esophagitis, Peptic; Famotidine; Histamine H2 Ant

1988
Do anticholinergics interact with histamine H2 receptor antagonists on night intragastric acidity in active duodenal ulcer patients?
    The American journal of gastroenterology, 1988, Volume: 83, Issue:12

    Topics: Adult; Circadian Rhythm; Drug Interactions; Drug Therapy, Combination; Duodenal Ulcer; Famotidine; G

1988
[Acute treatment of duodenal ulcer. Results of an open multicenter study with famotidine nocte].
    Fortschritte der Medizin, 1988, May-10, Volume: 106, Issue:14

    Topics: Anti-Ulcer Agents; Clinical Trials as Topic; Drug Administration Schedule; Duodenal Ulcer; Famotidin

1988
Famotidine versus cimetidine in the treatment of acute duodenal ulcer. Double-blind, randomized clinical trial comparing nocturnal administration of 40 mg famotidine to 800 mg cimetidine.
    Digestion, 1988, Volume: 39, Issue:3

    Topics: Acute Disease; Adult; Aged; Anti-Ulcer Agents; Cimetidine; Clinical Trials as Topic; Double-Blind Me

1988
Famotidine in the short and long-term treatment of duodenal ulcer.
    Acta gastroenterologica Latinoamericana, 1988, Volume: 18, Issue:2

    Topics: Anti-Ulcer Agents; Clinical Trials as Topic; Double-Blind Method; Duodenal Ulcer; Famotidine; Female

1988
Famotidine in the management of duodenal ulcer: an analysis of multicenter findings worldwide.
    Clinical therapeutics, 1988, Volume: 10, Issue:4

    Topics: Drug Administration Schedule; Duodenal Ulcer; Evaluation Studies as Topic; Famotidine; Humans; Meta-

1988
A comparison of the effects on intragastric acidity of bedtime or dinnertime administration of a once daily dose of famotidine.
    European journal of clinical pharmacology, 1988, Volume: 35, Issue:2

    Topics: Adult; Anti-Ulcer Agents; Double-Blind Method; Drug Administration Schedule; Duodenal Ulcer; Famotid

1988
Continuous intravenous infusions of famotidine maintain high intragastric pH in duodenal ulcer.
    Gut, 1988, Volume: 29, Issue:4

    Topics: Adult; Aged; Anti-Ulcer Agents; Clinical Trials as Topic; Double-Blind Method; Duodenal Ulcer; Famot

1988
Continuous 24-hour intragastric pH monitoring in the evaluation of the effect of a nightly dose of famotidine, ranitidine and placebo on gastric acidity of patients with duodenal ulcer.
    Digestion, 1987, Volume: 37, Issue:2

    Topics: Adult; Anti-Ulcer Agents; Clinical Trials as Topic; Duodenal Ulcer; Famotidine; Female; Gastric Acid

1987
Famotidine in the short-term treatment of duodenal ulcer and of concomitant peptic lesions: comparison with cimetidine.
    International journal of clinical pharmacology research, 1988, Volume: 8, Issue:2

    Topics: Cimetidine; Duodenal Ulcer; Famotidine; Female; Humans; Male; Middle Aged; Peptic Ulcer; Thiazoles

1988
Summary of the 30th meeting of the Food and Drug Administration Gastrointestinal Drugs Advisory Committee January 16-17, 1986.
    The American journal of gastroenterology, 1986, Volume: 81, Issue:6

    Topics: Aluminum; Cimetidine; Clinical Trials as Topic; Duodenal Ulcer; Famotidine; Humans; Peptic Ulcer; Su

1986
Effects of 800 mg cimetidine once daily on gastric acid secretion.
    Scandinavian journal of gastroenterology. Supplement, 1986, Volume: 121

    Topics: Administration, Oral; Cimetidine; Circadian Rhythm; Clinical Trials as Topic; Duodenal Ulcer; Famoti

1986
[Acute therapy of duodenal ulcer. Comparison of famotidine and ranitidine in a single evening dose].
    Fortschritte der Medizin, 1987, Feb-20, Volume: 105, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Ulcer Agents; Clinical Trials as Topic; Double-Blind Me

1987
Famotidine once-a-day in the management of duodenal ulcer: the U.S. placebo-controlled experience.
    Journal of clinical gastroenterology, 1987, Volume: 9 Suppl 2

    Topics: Anti-Ulcer Agents; Double-Blind Method; Drug Administration Schedule; Duodenal Ulcer; Famotidine; Hu

1987

Other Studies

67 other studies available for famotidine and Curling Ulcer

ArticleYear
[Prophylaxis of an acute postoperative pancreatitis and the stress ulcers occurrence after operations, performed on organs of hepatopancreatoduodenal zone, using miniinvasive and open access].
    Klinichna khirurhiia, 2014, Issue:4

    Topics: Acute Disease; Drug Administration Schedule; Drug Dosage Calculations; Duodenal Ulcer; Endoscopy, Ga

2014
A fixed-dose combination ibuprofen and famotidine (Duexis).
    The Medical letter on drugs and therapeutics, 2011, Oct-31, Volume: 53, Issue:1376

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Drug Combinations; Duodenal Ulcer; F

2011
Editorial: single-tablet ibuprofen/double-dose famotidine for reduction of gastric and duodenal ulcers (REDUCE Trials): what can be reduced?
    The American journal of gastroenterology, 2012, Volume: 107, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Duodenal Ulcer; Famotidine; Female; Huma

2012
[Pharmacotherapy of non-associated with Helicobacter pylori ulcer].
    Klinicheskaia meditsina, 2002, Volume: 80, Issue:10

    Topics: Adult; Antacids; Anti-Ulcer Agents; Duodenal Ulcer; Famotidine; Female; Helicobacter pylori; Humans;

2002
Effects of three H2-receptor antagonists (cimetidine, famotidine, ranitidine) on serum gastrin level.
    International journal of clinical pharmacology research, 2002, Volume: 22, Issue:2

    Topics: Adult; Anti-Ulcer Agents; Area Under Curve; Cimetidine; Duodenal Ulcer; Famotidine; Female; Gastrins

2002
Effect of exogenous administration of transforming growth factor-beta and famotidine on the healing of duodenal ulcer under the impact of indomethacin.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2003, Volume: 35, Issue:6

    Topics: Animals; Duodenal Ulcer; Famotidine; Gastric Acid; Indomethacin; Male; Rats; Rats, Wistar; Transform

2003
[Clinical and economic analysis of the application of ranitidine and famotidine for treatment of duodenal ulcers].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2005, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Drug Costs; Duodenal Ulcer; Famotidin

2005
[Complex evaluation of the action of inhibitors of hydrochloric acid secretion on gastric function in ulcer disease].
    Terapevticheskii arkhiv, 2006, Volume: 78, Issue:2

    Topics: Adult; Anti-Ulcer Agents; Drug Therapy, Combination; Duodenal Ulcer; Enzyme Inhibitors; Famotidine;

2006
Effects of antiulcer agents on healing of mepirizole-induced duodenal ulcers in rats.
    Digestion, 1983, Volume: 27, Issue:1

    Topics: Aluminum Hydroxide; Animals; Anti-Ulcer Agents; Cimetidine; Drug Combinations; Duodenal Ulcer; Epiri

1983
[Effect of Famotidine in gastric acidity, plasma secretin and gastrin in duodenal ulcer patients. With reference to 24-hour intragastric pH monitoring].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1984, Volume: 81, Issue:3

    Topics: Adult; Duodenal Ulcer; Famotidine; Female; Gastric Acid; Gastric Acidity Determination; Gastric Muco

1984
[Effects of protective agents on ulcer formation].
    Nihon rinsho. Japanese journal of clinical medicine, 1984, Volume: 42, Issue:1

    Topics: Adult; Animals; Cimetidine; Dogs; Duodenal Ulcer; Famotidine; Gastric Juice; Gastric Mucosa; Humans;

1984
Peptic ulcer disease in adolescence: changing concepts in the age of Helicobacter pylori.
    The Gastroenterologist, 1994, Volume: 2, Issue:4

    Topics: Adolescent; Adult; Anti-Ulcer Agents; Duodenal Ulcer; Famotidine; Helicobacter Infections; Helicobac

1994
[Maintenance therapy with antiulcer drugs: review of 71 cases].
    Atencion primaria, 1995, Feb-15, Volume: 15, Issue:2

    Topics: Aluminum Hydroxide; Antacids; Anti-Ulcer Agents; Carbonates; Cross-Over Studies; Duodenal Ulcer; Fam

1995
Blood alcohol levels after prolonged histamine-2-receptor antagonist treatment.
    Annals of internal medicine, 1994, Jan-01, Volume: 120, Issue:1

    Topics: Duodenal Ulcer; Ethanol; Famotidine; Histamine H2 Antagonists; Humans; Male; Random Allocation; Rani

1994
YM022 [(R)-1-[2,3-dihydro-1-(2'-methylphenacyl)-2-oxo-5-phenyl- 1H-1,4-benzodiazepin-3-yl]-3-(3-methylphenyl)urea], a potent and selective gastrin/cholecystokinin-B receptor antagonist, prevents gastric and duodenal lesions in rats.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Benzodiazepines; Duodenal Ulcer; Epirizole; Ethanol; Famotidine; Gastric

1994
Inhibition of phase III activity by acid in canine stomach.
    Regulatory peptides, 1994, Jun-16, Volume: 52, Issue:1

    Topics: Animals; Disease Models, Animal; Dogs; Duodenal Ulcer; Electrodes; Electrophysiology; Famotidine; Fe

1994
Maintenance of intragastric pH > 4 with famotidine in duodenal ulcer patients: factors influencing drug requirements.
    Gut, 1994, Volume: 35, Issue:6

    Topics: Adult; Aged; Drug Delivery Systems; Duodenal Ulcer; Duodenum; Famotidine; Female; Fibrosis; Gastric

1994
Healing-promoting action of the new histamine H2-receptor antagonist N-ethyl-N'-[3-[3-(piperidinomethyl)phenoxy]propyl]urea with dual action on chronic gastric and duodenal ulcers induced by acetic acid in rats.
    Arzneimittel-Forschung, 1993, Volume: 43, Issue:2

    Topics: Acetates; Animals; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Duodenal Ulcer; Famotidine;

1993
Hepatitis following treatments with famotidine and then cimetidine.
    The Annals of pharmacotherapy, 1994, Volume: 28, Issue:1

    Topics: Chemical and Drug Induced Liver Injury; Cimetidine; Duodenal Ulcer; Famotidine; Fatty Liver; Female;

1994
Long term acid suppressing treatment in general practice.
    BMJ (Clinical research ed.), 1994, Mar-26, Volume: 308, Issue:6932

    Topics: Abdominal Pain; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal;

1994
[Evaluation of microsomal enzyme function in the liver in patients with duodenal ulcer treated with famotidine].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1993, Volume: 46, Issue:9-10

    Topics: Adult; Duodenal Ulcer; Famotidine; Female; Humans; Male; Microsomes, Liver; Middle Aged

1993
[Assessment of microsomal enzyme function in liver of patients with duodenal ulcer treated with famotidine].
    Polskie Archiwum Medycyny Wewnetrznej, 1993, Volume: 89, Issue:3

    Topics: Adult; Aminopyrine; Breath Tests; Duodenal Ulcer; Famotidine; Female; Humans; Male; Microsomes, Live

1993
Gastric acid inhibits antral phase III activity in duodenal ulcer patients.
    Digestive diseases and sciences, 1993, Volume: 38, Issue:5

    Topics: Adult; Duodenal Ulcer; Duodenum; Famotidine; Female; Gastric Acid; Gastric Acidity Determination; Ga

1993
The effect of the combination therapy with sucralfate and famotidine on experimentally induced duodenal ulcers in rats.
    Pflugers Archiv : European journal of physiology, 1996, Volume: 431, Issue:6 Suppl 2

    Topics: Animals; Anti-Ulcer Agents; Cysteamine; Drug Therapy, Combination; Duodenal Ulcer; Famotidine; Femal

1996
New drug to prevent NSAID-related ulcers.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1996, Oct-15, Volume: 155, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Drug Therapy, Combination; Duodenal Ulce

1996
[Ulfamid in the combined therapy of gastric and duodenal peptic ulcer].
    Terapevticheskii arkhiv, 1997, Volume: 69, Issue:2

    Topics: Adult; Aged; Amoxicillin; Anti-Ulcer Agents; Combined Modality Therapy; Drug Evaluation; Drug Therap

1997
[Conservative treatment of ulcer hemorrhage with histamine H2 antagonists].
    Khirurgiia, 1997, Issue:5

    Topics: Adolescent; Adult; Duodenal Ulcer; Endoscopy, Digestive System; Famotidine; Follow-Up Studies; Hista

1997
Enhancement of neutrophil infiltration in the corpus after failure of Helicobacter pylori eradication.
    Journal of clinical gastroenterology, 1997, Volume: 25 Suppl 1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Biop

1997
Bone mineral density in patients taking H2-receptor antagonist.
    Calcified tissue international, 1998, Volume: 62, Issue:4

    Topics: Adult; Aged; Bone Density; Case-Control Studies; Cimetidine; Duodenal Ulcer; Famotidine; Female; His

1998
[Bicarbonate deficiency and duodenal peptic ulcer].
    Terapevticheskii arkhiv, 1998, Volume: 70, Issue:2

    Topics: Acid-Base Equilibrium; Adult; Bicarbonates; Chronic Disease; Duodenal Ulcer; Famotidine; Female; Gas

1998
Effect of chronic acid inhibition on duodenal bulb gastric metaplasia and Helicobacter pylori.
    Italian journal of gastroenterology and hepatology, 1998, Volume: 30, Issue:2

    Topics: Adult; Case-Control Studies; Duodenal Ulcer; Duodenum; Famotidine; Female; Gastric Mucosa; Helicobac

1998
[Antisecretory effects of quamatel and gastrocepin in duodenal ulcer: comparison with intragastric pH-metry].
    Klinicheskaia meditsina, 1998, Volume: 76, Issue:8

    Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Duodenal Ulcer; Famotidine; Female; Follow-Up Studies; G

1998
[Famotidine (quamatel) for treatment of ulcer disease].
    Khirurgiia, 1999, Issue:1

    Topics: Adolescent; Adult; Duodenal Ulcer; Endoscopy, Digestive System; Famotidine; Follow-Up Studies; Hista

1999
Simple closure of perforated duodenal ulcer.
    Journal of the Indian Medical Association, 1998, Volume: 96, Issue:10

    Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Duodenal Ulcer; Famotidine; Female; Humans; Male; Middle

1998
The long-term reinfection rate and the course of duodenal ulcer disease after eradication of Helicobacter pylori in a developing country.
    The American journal of gastroenterology, 2000, Volume: 95, Issue:1

    Topics: Adolescent; Adult; Aged; Amoxicillin; Anti-Ulcer Agents; Chile; Developing Countries; Drug Therapy,

2000
[24-hour monitoring of gastric juice pH in assessment of anti-ulcer treatment].
    Terapevticheskii arkhiv, 2000, Volume: 72, Issue:2

    Topics: Adult; Amoxicillin; Anti-Infective Agents; Anti-Ulcer Agents; Biopsy; Circadian Rhythm; Drug Therapy

2000
[Famotidin (quamatel) in the treatment of gastroduodenal ulcer].
    Khirurgiia, 2000, Issue:6

    Topics: Adult; Drug Administration Routes; Duodenal Ulcer; Endoscopy, Digestive System; Famotidine; Female;

2000
[Quamatel application in three-drug eradication therapy of duodenal ulcer and gastroduodenal ulcerations associated with helicobacter pylori infection].
    Klinicheskaia meditsina, 2000, Volume: 78, Issue:6

    Topics: Adolescent; Adult; Amoxicillin; Anti-Bacterial Agents; Drug Therapy, Combination; Duodenal Ulcer; Fa

2000
[Experience in clinical use of quamatel in upper gastrointestinal hemorrhage].
    Khirurgiia, 2001, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Duodenal Ulcer; Famotidine; Female; Gastroin

2001
[H2 blockers in the treatment of bleeding gastroduodenal ulcers].
    Khirurgiia, 2001, Issue:10

    Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Duodenal Ulcer; Duodenoscopy; Famotidine; Female; Gastro

2001
[Effect of exogenous administration of platelet-derived growth factor and epidermal growth factor on duodenal ulcer healing in rats treated with indomethacin].
    Gastroenterologia y hepatologia, 2002, Volume: 25, Issue:5

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Duodenal Ulcer; Ep

2002
[The gastric mucigenous function in the treatment of patients with ulcer with various antisecretory preparations].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2002, Issue:2

    Topics: Adult; Anti-Ulcer Agents; Duodenal Ulcer; Enzyme Inhibitors; Famotidine; Female; Gastric Acidity Det

2002
Primary hyperparathyroidism with duodenal ulcer and H. pylori infection.
    Internal medicine (Tokyo, Japan), 2002, Volume: 41, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenoma; Aged; Anti-Ulcer Agents; Benzimidazoles; Duodenal

2002
[Prevention of the recurrence of duodenal ulcer with famotidine. Report of experiences with long-term therapy in an open clinical study].
    Wiener medizinische Wochenschrift (1946), 1992, Volume: 142, Issue:18

    Topics: Adult; Dose-Response Relationship, Drug; Drug Administration Schedule; Duodenal Ulcer; Duodenoscopy;

1992
Effects of a proton pump inhibitor, AG-1749 (lansoprazole), on reflux esophagitis and experimental ulcers in rats.
    Japanese journal of pharmacology, 1991, Volume: 55, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Duodenal Ulcer; Duodenum; Esoph

1991
Definition for idiopathic gastric acid hypersecretion. A statistical and functional evaluation.
    Digestive diseases and sciences, 1991, Volume: 36, Issue:10

    Topics: Adult; Cimetidine; Duodenal Ulcer; Famotidine; Female; Gastric Acid; Humans; Male; Middle Aged; Rani

1991
The histological maturity of regenerating mucosa of healed duodenal ulcer and ulcer recurrence after treatment with H2-antagonist.
    The American journal of gastroenterology, 1990, Volume: 85, Issue:8

    Topics: Adolescent; Adult; Aged; Cimetidine; Duodenal Ulcer; Duodenoscopy; Famotidine; Female; Histamine H2

1990
Effects of FRG-8701 on gastric acid secretion, gastric mucosal lesions by necrotizing agents and experimental gastric or duodenal ulcer in rats.
    Japanese journal of pharmacology, 1990, Volume: 54, Issue:3

    Topics: Acetamides; Animals; Cimetidine; Duodenal Ulcer; Famotidine; Gastric Acid; Gastric Mucosa; Guinea Pi

1990
High doses of ranitidine in maintenance therapy of duodenal ulcer patients.
    Scandinavian journal of gastroenterology. Supplement, 1990, Volume: 178

    Topics: Cimetidine; Duodenal Ulcer; Famotidine; Humans; Ranitidine; Recurrence; Smoking

1990
Effect of an endogenous satiety substance, 2-buten-4-olide, on gastric acid secretion and experimental ulceration in rats.
    Physiology & behavior, 1990, Volume: 47, Issue:1

    Topics: 4-Butyrolactone; Animals; Cimetidine; Cysteamine; Deoxyglucose; Duodenal Ulcer; Famotidine; Furans;

1990
A single nocte dose of famotidine in the treatment of duodenal ulcer.
    JPMA. The Journal of the Pakistan Medical Association, 1989, Volume: 39, Issue:4

    Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Duodenal Ulcer; Famotidine; Female; Histamine H2 Antagon

1989
[Famotidine in the short and long term treatment of duodenal ulcer: clinical and physiopathologic study].
    Giornale di clinica medica, 1989, Volume: 70, Issue:3

    Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Drug Administration Schedule; Drug Evaluation; Duodenal

1989
Failure of single night-time dose of H2-receptor antagonists in the treatment of duodenal ulcer patients with bulbar stenosis.
    The American journal of gastroenterology, 1989, Volume: 84, Issue:11

    Topics: Adult; Aged; Drug Administration Schedule; Duodenal Obstruction; Duodenal Ulcer; Famotidine; Female;

1989
Low doses of H2 antagonists and interaction with anticholinergics.
    The American journal of gastroenterology, 1989, Volume: 84, Issue:11

    Topics: Drug Synergism; Duodenal Ulcer; Famotidine; Gastric Acidity Determination; Humans; Pirenzepine; Rani

1989
[Duodenal ulcer, study of gastric secretion and rational treatment with famotidine in different doses].
    Annales de gastroenterologie et d'hepatologie, 1989, Volume: 25, Issue:5

    Topics: Duodenal Ulcer; Famotidine; Gastric Acid; Humans

1989
Clinical pharmacology of famotidine.
    Digestion, 1985, Volume: 32 Suppl 1

    Topics: Animals; Cimetidine; Circadian Rhythm; Dogs; Dose-Response Relationship, Drug; Duodenal Ulcer; Famot

1985
[Famotidine. Pharmacologic and clinical profile of the new histamine H2 receptor antagonist].
    Fortschritte der Medizin, 1986, Apr-17, Volume: 104, Issue:15

    Topics: Animals; Duodenal Ulcer; Famotidine; Guinea Pigs; Histamine H2 Antagonists; Humans; Kinetics; Stomac

1986
Famotidine. The ACG Committee on FDA-Related Matters with primary authorship by G. Friedman. American College of Gastroenterology.
    The American journal of gastroenterology, 1987, Volume: 82, Issue:6

    Topics: Duodenal Ulcer; Famotidine; Gastric Acid; Histamine H2 Antagonists; Humans; Recurrence; Stomach Ulce

1987
Antisecretory and antiulcer effect of the H2-receptor antagonist famotidine in the rat: comparison with ranitidine.
    British journal of pharmacology, 1987, Volume: 92, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Duodenal Ulcer; Famotidine; Female; Gastric Emptying; Gastric Mucosa; Hi

1987
Effect of mifentidine on mepirizole-induced duodenal ulcer in the rat.
    Pharmacological research communications, 1987, Volume: 19, Issue:12

    Topics: Animals; Anti-Ulcer Agents; Cimetidine; Dose-Response Relationship, Drug; Duodenal Ulcer; Duodenum;

1987
[Famotidine treatment of patients with gastric and duodenal ulcers. A comparative study with once or twice-a-day administration].
    La Clinica terapeutica, 1987, Aug-15, Volume: 122, Issue:3

    Topics: Adult; Aged; Anti-Ulcer Agents; Drug Evaluation; Duodenal Ulcer; Famotidine; Histamine H2 Antagonist

1987
The cost-effectiveness of maintenance therapy for duodenal ulceration with an H2-antagonist.
    Alimentary pharmacology & therapeutics, 1988, Volume: 2, Issue:4

    Topics: Cost-Benefit Analysis; Duodenal Ulcer; Famotidine; Histamine H2 Antagonists; Humans

1988
Refractory duodenal ulcers (nonhealing duodenal ulcers with standard doses of antisecretory medication).
    Digestive diseases and sciences, 1989, Volume: 34, Issue:2

    Topics: Adult; Aged; Anti-Ulcer Agents; Cimetidine; Duodenal Ulcer; Famotidine; Female; Gastric Acid; Humans

1989
[Famotidine in the therapy and prevention of duodenal ulcer].
    La Clinica terapeutica, 1988, Oct-31, Volume: 127, Issue:2

    Topics: Adult; Anti-Ulcer Agents; Duodenal Ulcer; Famotidine; Female; Humans; Male; Ranitidine; Thiazoles

1988
Famotidine has no significant effect on gonadal function in man.
    Gastroenterologie clinique et biologique, 1988, Volume: 12, Issue:1

    Topics: Administration, Oral; Adult; Anti-Ulcer Agents; Duodenal Ulcer; Famotidine; Follicle Stimulating Hor

1988
Healing and relapse rates of duodenal ulcer with various H2 receptor antagonists.
    JPMA. The Journal of the Pakistan Medical Association, 1988, Volume: 38, Issue:12

    Topics: Adolescent; Adult; Anti-Ulcer Agents; Cimetidine; Duodenal Ulcer; Famotidine; Female; Humans; Male;

1988
Comparison of the effects of gastric antisecretory agents in healthy volunteers and patients with duodenal ulcer.
    Gut, 1986, Volume: 27, Issue:9

    Topics: Anti-Ulcer Agents; Cimetidine; Drug Administration Schedule; Duodenal Ulcer; Famotidine; Gastric Aci

1986