famotidine has been researched along with Crohn Disease in 4 studies
Famotidine: A competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion.
Crohn Disease: A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Histamine is a key immunoregulatory mediator in immediate-type hypersensitivity reactions and chronic inflammatory responses, in particular histamine suppresses proinflammatory responses to bacterial ligands, through histamine receptor 2 (H2R)." | 1.43 | Histamine Receptor 2 is Required to Suppress Innate Immune Responses to Bacterial Ligands in Patients with Inflammatory Bowel Disease. ( Akdis, CA; Ferstl, R; Frei, R; Groeger, D; Jutel, M; Konieczna, P; OʼMahony, L; Perez, NR; Schiavi, E; Smolinska, S, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Smolinska, S | 1 |
| Groeger, D | 1 |
| Perez, NR | 1 |
| Schiavi, E | 1 |
| Ferstl, R | 1 |
| Frei, R | 1 |
| Konieczna, P | 1 |
| Akdis, CA | 1 |
| Jutel, M | 1 |
| OʼMahony, L | 1 |
| Moriyama, T | 1 |
| Matsumoto, T | 1 |
| Jo, Y | 1 |
| Yada, S | 1 |
| Hirahashi, M | 1 |
| Yao, T | 1 |
| Iida, M | 1 |
| Miehsler, W | 1 |
| Püspök, A | 1 |
| Oberhuber, T | 1 |
| Vogelsang, H | 1 |
| Saunders, DR | 1 |
| Saunders, MD | 1 |
| Sillery, JK | 1 |
4 other studies available for famotidine and Crohn Disease
| Article | Year |
|---|---|
Histamine Receptor 2 is Required to Suppress Innate Immune Responses to Bacterial Ligands in Patients with Inflammatory Bowel Disease.
Topics: Adult; Animals; Case-Control Studies; Cells, Cultured; Colitis, Ulcerative; Crohn Disease; Cytokines | 2016 |
Mucosal proinflammatory cytokine and chemokine expression of gastroduodenal lesions in Crohn's disease.
Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Case-Control Studies; Chemokines; Crohn Disease; Cytokin | 2005 |
Impact of different therapeutic regimens on the outcome of patients with Crohn's disease of the upper gastrointestinal tract.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Crohn Disease; Data Interpretatio | 2001 |
Beneficial effects of glucose polymer and an H2-receptor blocker in a patient with a proximal ileostomy.
Topics: Adult; Carbohydrates; Combined Modality Therapy; Crohn Disease; Famotidine; Fluid Therapy; Histamine | 1989 |