Page last updated: 2024-09-03

ezogabine and Disease Models, Animal

ezogabine has been researched along with Disease Models, Animal in 40 studies

Research

Studies (40)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	12 (30.00)	29.6817
2010's	22 (55.00)	24.3611
2020's	6 (15.00)	2.80

Authors

Authors	Studies
Gao, ZB; Li, JL; Zhao, WM	1
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV	1
Chen, F; Gao, ZB; Hu, HN; Liu, HN; Liu, J; Nan, FJ; Pi, XP; Tian, FY; Xu, HY; Zhan, L; Zhang, YM	1
Huo, B; Jin, L; Li, H; Liu, R; Liu, S; Tang, L; Wang, Y; Yang, T; Zhang, F; Zhao, X	1
Allison, WT; Kanyo, R; Kurata, HT; Li, J; Locskai, LF; Wang, CK	1
Feng, C; Gao, R; Guo, J; He, Z; Qin, C; Ren, J; Wang, Q; Wang, Z; Zang, L; Zhao, C; Zhu, S	1
Krupa-Burtnik, A; Pietrzak, B; Zwierzyńska, E	1
Gautier, NM; Glasscock, E; Mishra, V; Vanhoof-Villalba, SL	1
Dawson-Scully, K; Jia, K; Kelly, SP; Minnerly, J; Risley, MG	1
Feng, XM; Li, GB; Liu, JY; Zhang, BL; Zhang, RS	1
Hayashi, H; Iwata, M; Matsumoto, T; Tsuchimori, N	1
Hatch, RJ; Petrou, S; Reid, CA	1
Chen, F; Chen, X; Gao, Z; Li, X; Nan, F; Pi, X; Wang, L; Xu, H; Zhan, L; Zhang, Y; Zhou, P	1
Cai, J; Fang, D; Li, S; Liu, XD; Ren, J; Xing, GG	1
Budde, T; Cerina, M; Coulon, P; Göbel, K; Kanyshkova, T; Meuth, P; Meuth, SG; Nguyen, XV; Pape, HC; Seidenbecher, T; Szkudlarek, HJ	1
Chen, GD; Salvi, R; Sheppard, AM	1
Chen, B; Chen, J; Li, H; Sun, R; Wang, F; Wang, X; Zhang, Y	1
Duignan, KM; Edwards, S; Furuya, T; Kalappa, BI; Soh, H; Tzingounis, AV; Tzounopoulos, T	1
Abd-Elsayed, AA; Gu, JG; Ikeda, R; Jia, Z; Li, M; Ling, J; Zuo, X	1
Bernal, L; Lopez-Garcia, JA; Roza, C	1
Calizo, RC; Chaudhury, D; Dietz, DM; Friedman, AK; Han, MH; Hawkins, A; Juarez, B; Ku, SM; Murrough, JW; Neve, RL; Ribadeneira, M; Walsh, JJ; Wong, EH; Zhang, H; Zhang, S	1
Carlton, SM; Du, J; Frost, JA; Li, L; Walters, ET; Wu, Z; Xie, F; Yang, Q; Zuo, Y	1
Czuczwar, SJ; Luszczki, JJ; Raszewski, G; Wu, JZ	1
Nielsen, AN; Redrobe, JP	1
Dencker, D; Husum, H	1
Auvin, S; Kwon, YS; Mazarati, A; Pineda, E; Sankar, R; Shin, D	1
Nodera, H; Rutkove, S; Spieker, A; Sung, M	1
Crean, CS; Gunthorpe, MJ; Large, CH; Nehlig, A; Sankar, R; Sokal, DM; Vanlandingham, KE; White, HS	1
Rheims, S; Ryvlin, P	1
Brueggemann, LI; Byron, KL; Kumar, L; Mani, BK; O'Dowd, J; Ross, M	1
Blackburn-Munro, G; Jensen, BS	1
Al-Qatari, M; Brown, DA; Brown, TA; Burbidge, SA; Dickenson, AH; Main, M; Marsh, SJ; Matthews, EA; Mistry, M; Passmore, GM; Selyanko, AA	1
Dost, R; Rostock, A; Rundfeldt, C	1
Frankel, WN; Otto, JF; White, HS; Wilcox, KS; Yang, Y	1
Richter, A; Rundfeldt, C; Sander, SE	1
Miura, Y	1
Johnson, BN; Qiu, C; Tallent, MK	1
Dencker, D; Dias, R; Husum, H; Pedersen, ML	1
Kwon, YS; Mazarati, A; Sankar, R; Shin, D; Wu, J	1
Armand, V; Heinemann, U; Rundfeldt, C	1

Reviews

2 review(s) available for ezogabine and Disease Models, Animal

Article	Year
Retigabine for partial onset seizures. Expert review of neurotherapeutics, 2012, Volume: 12, Issue:5 Topics: Animals; Anticonvulsants; Carbamates; Disease Models, Animal; Epilepsies, Partial; Humans; Phenylenediamines; Randomized Controlled Trials as Topic; Treatment Outcome	2012
[A new aspect in the research on antiepileptic drugs]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2007, Volume: 129, Issue:2 Topics: Acetamides; Amines; Animals; Anticonvulsants; Benzodiazepines; Carbamates; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Design; Gabapentin; gamma-Aminobutyric Acid; Humans; Lacosamide; Levetiracetam; Phenylenediamines; Piracetam; Pregabalin; Pregnanolone; Pyrrolidinones; Triazoles	2007

Article

Year

Retigabine for partial onset seizures.

Expert review of neurotherapeutics, 2012, Volume: 12, Issue:5

Topics: Animals; Anticonvulsants; Carbamates; Disease Models, Animal; Epilepsies, Partial; Humans; Phenylenediamines; Randomized Controlled Trials as Topic; Treatment Outcome

2012

[A new aspect in the research on antiepileptic drugs].

Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2007, Volume: 129, Issue:2

Topics: Acetamides; Amines; Animals; Anticonvulsants; Benzodiazepines; Carbamates; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Design; Gabapentin; gamma-Aminobutyric Acid; Humans; Lacosamide; Levetiracetam; Phenylenediamines; Piracetam; Pregabalin; Pregnanolone; Pyrrolidinones; Triazoles

2007

Other Studies

38 other study(ies) available for ezogabine and Disease Models, Animal

Article	Year
Identification and Evaluation of Antiepileptic Activity of C21 Steroidal Glycosides from the Roots of Cynanchum wilfordii. Journal of natural products, 2016, Jan-22, Volume: 79, Issue:1 Topics: Animals; Anticonvulsants; Cynanchum; Disease Models, Animal; Glycosides; Mice; Molecular Structure; Plant Roots; Pregnanes; Saponins; Seizures	2016
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49 Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection	2020
Discovery of HN37 as a Potent and Chemically Stable Antiepileptic Drug Candidate. Journal of medicinal chemistry, 2021, 05-13, Volume: 64, Issue:9 Topics: Animals; Anticonvulsants; Carbamates; Disease Models, Animal; Dogs; Drug Design; Drug Evaluation, Preclinical; Drug Stability; Electroshock; Half-Life; Humans; KCNQ Potassium Channels; Mice; Phenylenediamines; Protein Isoforms; Rats; Rats, Sprague-Dawley; Seizures; Structure-Activity Relationship	2021
Antinociceptive Efficacy of Retigabine and Flupirtine for Gout Arthritis Pain. Pharmacology, 2020, Volume: 105, Issue:7-8 Topics: Aminopyridines; Analgesics; Animals; Arthritis, Experimental; Arthritis, Gouty; Behavior, Animal; Carbamates; Disease Models, Animal; Hyperalgesia; KCNQ Potassium Channels; Male; Pain; Phenylenediamines; Rats; Rats, Sprague-Dawley; Uric Acid	2020
Functional and behavioral signatures of Kv7 activator drug subtypes. Epilepsia, 2020, Volume: 61, Issue:8 Topics: Anilides; Animals; Animals, Genetically Modified; Anticonvulsants; Bridged Bicyclo Compounds; Calcium; Carbamates; Disease Models, Animal; Drug Resistance; Epilepsy; In Vitro Techniques; KCNQ Potassium Channels; KCNQ2 Potassium Channel; KCNQ3 Potassium Channel; Luminescent Proteins; Membrane Potentials; Mutation; Neurons; Optical Imaging; Patch-Clamp Techniques; Phenylenediamines; Seizures; Zebrafish	2020
The Role of Potassium Channels in Chronic Stress-Induced Brain Injury. Biological & pharmaceutical bulletin, 2021, Feb-01, Volume: 44, Issue:2 Topics: Animals; Brain; Brain Injuries; Carbamates; Disease Models, Animal; Female; Humans; Neuroprotective Agents; Phenylenediamines; Potassium Channel Blockers; Potassium Channels; Rats; RNA-Seq; Signal Transduction; Stress, Psychological	2021
Beneficial effect of retigabine on memory in rats receiving ethanol. Pharmacological reports : PR, 2021, Volume: 73, Issue:2 Topics: Animals; Anticonvulsants; Brain; Carbamates; Disease Models, Animal; Ethanol; Hippocampus; Learning; Male; Maze Learning; Memory; Memory Disorders; Phenylenediamines; Rats; Rats, Wistar	2021
Pharmacogenetics of KCNQ channel activation in 2 potassium channelopathy mouse models of epilepsy. Epilepsia, 2018, Volume: 59, Issue:2 Topics: Animals; Anticonvulsants; Atrioventricular Block; Behavior, Animal; Bradycardia; Carbamates; Channelopathies; Death, Sudden; Disease Models, Animal; Drug Resistance; Drug Resistant Epilepsy; Electroencephalography; Epilepsy; Gene Expression Profiling; Heart Rate; KCNQ Potassium Channels; KCNQ1 Potassium Channel; KCNQ2 Potassium Channel; KCNQ3 Potassium Channel; Kv1.1 Potassium Channel; Mice; Nerve Tissue Proteins; Pharmacogenetics; Pharmacogenomic Testing; Phenylenediamines; RNA, Messenger; Transcriptome	2018
egl-4 modulates electroconvulsive seizure duration in C. elegans. Invertebrate neuroscience : IN, 2018, 05-30, Volume: 18, Issue:2 Topics: Animals; Anticonvulsants; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Carbamates; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Disease Models, Animal; Electroshock; Phenylenediamines; Recovery of Function; Seizures; Signal Transduction	2018
Retigabine attenuates focal cerebral ischemic injury through inhibiting mitochondria-dependent apoptotic pathway. European review for medical and pharmacological sciences, 2018, Volume: 22, Issue:15 Topics: Animals; Apoptosis; Brain Injuries; Carbamates; Caspase 3; Disease Models, Animal; Glutathione; JNK Mitogen-Activated Protein Kinases; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Mitochondria; Oxidative Stress; Phenylenediamines; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Superoxide Dismutase	2018
Activation of peripheral KCNQ channels attenuates inflammatory pain. Molecular pain, 2014, Feb-21, Volume: 10 Topics: Animals; Anthracenes; Anticonvulsants; Benzamides; Carbamates; Disease Models, Animal; Electric Stimulation; Exploratory Behavior; Formaldehyde; Freund's Adjuvant; Functional Laterality; Hyperalgesia; Inflammation; KCNQ Potassium Channels; Motor Skills Disorders; Pain; Pain Measurement; Pain Threshold; Phenylenediamines; Potassium Channel Blockers; Pyridines; Rats	2014
Enhanced in vitro CA1 network activity in a sodium channel β1(C121W) subunit model of genetic epilepsy. Epilepsia, 2014, Volume: 55, Issue:4 Topics: Action Potentials; Animals; Anticonvulsants; CA1 Region, Hippocampal; Carbamates; Carbamazepine; Disease Models, Animal; Epilepsy; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Net; Organ Culture Techniques; Phenylenediamines; Up-Regulation; Voltage-Gated Sodium Channel beta-1 Subunit	2014
P-retigabine: an N-propargyled retigabine with improved brain distribution and enhanced antiepileptic activity. Molecular pharmacology, 2015, Volume: 87, Issue:1 Topics: Action Potentials; Animals; Anticonvulsants; Carbamates; Cells, Cultured; CHO Cells; Cricetulus; Disease Models, Animal; Dose-Response Relationship, Drug; Hippocampus; KCNQ Potassium Channels; Male; Mice; Phenylenediamines; Seizures	2015
Suppression of KCNQ/M (Kv7) potassium channels in the spinal cord contributes to the sensitization of dorsal horn WDR neurons and pain hypersensitivity in a rat model of bone cancer pain. Oncology reports, 2015, Volume: 33, Issue:3 Topics: Acetylcholine; Animals; Anthracenes; Bone Neoplasms; Carbamates; Disease Models, Animal; Female; Hyperalgesia; KCNQ Potassium Channels; Membrane Transport Modulators; Neoplasm Transplantation; Pain; Phenylenediamines; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Spinal Cord	2015
Thalamic Kv 7 channels: pharmacological properties and activity control during noxious signal processing. British journal of pharmacology, 2015, Volume: 172, Issue:12 Topics: Action Potentials; Acute Pain; Animals; Anthracenes; Brain; Carbamates; Disease Models, Animal; KCNQ Potassium Channels; KCNQ2 Potassium Channel; KCNQ3 Potassium Channel; Mice; Mice, Inbred C57BL; Neurons; Pain Threshold; Phenylenediamines; Thalamus	2015
Potassium ion channel openers, Maxipost and Retigabine, protect against peripheral salicylate ototoxicity in rats. Hearing research, 2015, Volume: 327 Topics: Acoustic Stimulation; Animals; Carbamates; Cochlea; Cochlear Microphonic Potentials; Cytoprotection; Disease Models, Animal; Hearing Loss, Sensorineural; Indoles; KCNQ Potassium Channels; Large-Conductance Calcium-Activated Potassium Channels; Male; Otoacoustic Emissions, Spontaneous; Phenylenediamines; Potassium Channels; Rats, Sprague-Dawley; Sodium Salicylate; Tinnitus	2015
Antinociceptive Efficacy of Retigabine in the Monosodium Lodoacetate Rat Model for Osteoarthritis Pain. Pharmacology, 2015, Volume: 95, Issue:5-6 Topics: Analgesics; Animals; Arthritis, Experimental; Behavior, Animal; Carbamates; Disease Models, Animal; Iodoacetates; Knee Joint; Male; Membrane Transport Modulators; Osteoarthritis; Pain; Phenylenediamines; Rats, Sprague-Dawley; Treatment Outcome	2015
Potent KCNQ2/3-specific channel activator suppresses in vivo epileptic activity and prevents the development of tinnitus. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Jun-10, Volume: 35, Issue:23 Topics: Animals; Animals, Newborn; Anticonvulsants; Carbamates; Disease Models, Animal; Epilepsy; Evoked Potentials, Auditory, Brain Stem; Female; HEK293 Cells; Homeodomain Proteins; Humans; In Vitro Techniques; KCNQ Potassium Channels; KCNQ2 Potassium Channel; Male; Membrane Potentials; Mice; Mice, Inbred ICR; Mice, Knockout; Mutation; Phenylenediamines; Rats; Rats, Sprague-Dawley; Tinnitus; Transcription Factors	2015
KCNQ channels in nociceptive cold-sensing trigeminal ganglion neurons as therapeutic targets for treating orofacial cold hyperalgesia. Molecular pain, 2015, Jul-31, Volume: 11 Topics: Action Potentials; Animals; Carbamates; Chronic Disease; Cold Temperature; Constriction; Disease Models, Animal; Face; Hyperalgesia; KCNQ Potassium Channels; Male; Molecular Targeted Therapy; Neurons; Nociception; Organoplatinum Compounds; Oxaliplatin; Phenylenediamines; Rats, Sprague-Dawley; Thermosensing; Trigeminal Ganglion	2015
Spontaneous activity in C-fibres after partial damage to the saphenous nerve in mice: Effects of retigabine. European journal of pain (London, England), 2016, Volume: 20, Issue:8 Topics: Action Potentials; Animals; Axotomy; Carbamates; Disease Models, Animal; Male; Membrane Transport Modulators; Mice; Nerve Fibers; Neuralgia; Neuroma; Peripheral Nerves; Phenylenediamines	2016
KCNQ channel openers reverse depressive symptoms via an active resilience mechanism. Nature communications, 2016, 05-24, Volume: 7 Topics: Adaptation, Psychological; Animals; Antidepressive Agents; Behavior, Animal; Carbamates; Depressive Disorder, Major; Disease Models, Animal; Dopaminergic Neurons; Electrophysiological Phenomena; Humans; KCNQ3 Potassium Channel; Male; Membrane Transport Modulators; Mice; Mice, Inbred C57BL; Phenylenediamines; Resilience, Psychological; Stress, Psychological; Ventral Tegmental Area	2016
Activation of KCNQ Channels Suppresses Spontaneous Activity in Dorsal Root Ganglion Neurons and Reduces Chronic Pain after Spinal Cord Injury. Journal of neurotrauma, 2017, 03-15, Volume: 34, Issue:6 Topics: Animals; Behavior, Animal; Carbamates; Chronic Pain; Disease Models, Animal; Ganglia, Spinal; KCNQ Potassium Channels; Male; Membrane Transport Modulators; Phenylenediamines; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries	2017
Isobolographic characterization of interactions of retigabine with carbamazepine, lamotrigine, and valproate in the mouse maximal electroshock-induced seizure model. Naunyn-Schmiedeberg's archives of pharmacology, 2009, Volume: 379, Issue:2 Topics: Animals; Anticonvulsants; Avoidance Learning; Behavior, Animal; Brain; Carbamates; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Electroshock; Injections, Intraperitoneal; Lamotrigine; Male; Memory; Mice; Motor Activity; Muscle Strength; Phenylenediamines; Psychomotor Performance; Seizures; Triazines; Valproic Acid	2009
Effects of neuronal Kv7 potassium channel activators on hyperactivity in a rodent model of mania. Behavioural brain research, 2009, Mar-17, Volume: 198, Issue:2 Topics: Amphetamine; Animals; Anticonvulsants; Antimanic Agents; Benzamides; Bipolar Disorder; Carbamates; Central Nervous System Stimulants; Chlordiazepoxide; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Hyperkinesis; Indoles; Injections, Intraperitoneal; KCNQ Potassium Channels; Lamotrigine; Lithium Compounds; Male; Mice; Mice, Inbred C57BL; Motor Activity; Phenylenediamines; Pyridines; Triazines	2009
Antimanic efficacy of retigabine in a proposed mouse model of bipolar disorder. Behavioural brain research, 2010, Feb-11, Volume: 207, Issue:1 Topics: Amphetamine; Analysis of Variance; Animals; Anticonvulsants; Antimanic Agents; Behavior, Animal; Bipolar Disorder; Carbamates; Disease Models, Animal; Dose-Response Relationship, Drug; Food Preferences; Lithium Chloride; Male; Mice; Motor Activity; Phenylenediamines; Saccharin; Treatment Outcome	2010
Evaluation of development-specific targets for antiepileptogenic therapy using rapid kindling. Epilepsia, 2010, Volume: 51 Suppl 3 Topics: Age Factors; Animals; Animals, Newborn; Anticonvulsants; Bumetanide; Carbamates; Disease Models, Animal; Fructose; Hippocampus; Kindling, Neurologic; Phenylenediamines; Rats; Topiramate	2010
Neuroprotective effects of Kv7 channel agonist, retigabine, for cisplatin-induced peripheral neuropathy. Neuroscience letters, 2011, Nov-21, Volume: 505, Issue:3 Topics: Action Potentials; Animals; Carbamates; Cisplatin; Disease Models, Animal; Drug Interactions; Injections, Intraperitoneal; Male; Mice; Neural Conduction; Neuroprotective Agents; Peripheral Nervous System Diseases; Phenylenediamines; Potassium Channel Blockers; Time Factors	2011
The spectrum of anticonvulsant efficacy of retigabine (ezogabine) in animal models: implications for clinical use. Epilepsia, 2012, Volume: 53, Issue:3 Topics: Animals; Anticonvulsants; Carbamates; Disease Models, Animal; Drug Synergism; Epilepsy; Humans; KCNQ Potassium Channels; Neurons; Phenylenediamines; Treatment Outcome	2012
Vascular KCNQ (Kv7) potassium channels as common signaling intermediates and therapeutic targets in cerebral vasospasm. Journal of cardiovascular pharmacology, 2013, Volume: 61, Issue:1 Topics: Animals; Anthracenes; Arginine Vasopressin; Basilar Artery; Carbamates; Celecoxib; Disease Models, Animal; Endothelin-1; KCNQ Potassium Channels; Male; Membrane Transport Modulators; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Myography; Patch-Clamp Techniques; Phenylenediamines; Potassium Channel Blockers; Pyrazoles; Rats; Rats, Sprague-Dawley; Serotonin; Signal Transduction; Subarachnoid Hemorrhage; Sulfonamides; Time Factors; Vasoconstriction; Vasoconstrictor Agents; Vasospasm, Intracranial	2013
The anticonvulsant retigabine attenuates nociceptive behaviours in rat models of persistent and neuropathic pain. European journal of pharmacology, 2003, Jan-24, Volume: 460, Issue:2-3 Topics: Animals; Anthracenes; Anticonvulsants; Behavior, Animal; Carbamates; Disease Models, Animal; Dose-Response Relationship, Drug; Hindlimb; Male; Neuralgia; Pain Measurement; Phenylenediamines; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Time Factors	2003
KCNQ/M currents in sensory neurons: significance for pain therapy. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Aug-06, Volume: 23, Issue:18 Topics: Animals; Anthracenes; Anura; Carbamates; Cells, Cultured; CHO Cells; Cricetinae; Disease Models, Animal; Ganglia, Spinal; Hyperalgesia; Indoles; Male; Neurons, Afferent; Oocytes; Pain; Pain Management; Pain Measurement; Patch-Clamp Techniques; Phenylenediamines; Potassium Channel Blockers; Potassium Channels; Pyridines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Transfection	2003
The anti-hyperalgesic activity of retigabine is mediated by KCNQ potassium channel activation. Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 369, Issue:4 Topics: Acute Disease; Amines; Analgesics, Opioid; Animals; Carbamates; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Indoles; Ion Channel Gating; KCNQ2 Potassium Channel; KCNQ3 Potassium Channel; Male; Mice; Peripheral Nervous System Diseases; Phenylenediamines; Physical Stimulation; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Pyridines; Rats; Rats, Wistar; Spinal Nerves; Touch; Tramadol	2004
Mice carrying the szt1 mutation exhibit increased seizure susceptibility and altered sensitivity to compounds acting at the m-channel. Epilepsia, 2004, Volume: 45, Issue:9 Topics: Animals; Anticonvulsants; Carbamates; Disease Models, Animal; Electroshock; Female; Genetic Predisposition to Disease; Indoles; KCNQ2 Potassium Channel; KCNQ3 Potassium Channel; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Mutant Strains; Mutation; Nerve Tissue Proteins; Phenylenediamines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Pyridines; Receptors, Nicotinic; Seizures; Sequence Deletion	2004
Antidystonic effects of Kv7 (KCNQ) channel openers in the dt sz mutant, an animal model of primary paroxysmal dystonia. British journal of pharmacology, 2006, Volume: 149, Issue:6 Topics: Animals; Carbamates; Cricetinae; Disease Models, Animal; Dystonia; Mesocricetus; Phenylenediamines; Potassium Channels	2006
K+ M-current regulates the transition to seizures in immature and adult hippocampus. Epilepsia, 2007, Volume: 48, Issue:11 Topics: Action Potentials; Animals; Anticonvulsants; Carbamates; Disease Models, Animal; Epilepsy, Benign Neonatal; Hippocampus; Humans; Indoles; Male; Mutation; Phenylenediamines; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures	2007
Effect of the new antiepileptic drug retigabine in a rodent model of mania. Epilepsy & behavior : E&B, 2008, Volume: 12, Issue:1 Topics: Amphetamine; Animals; Anticonvulsants; Behavior, Animal; Bipolar Disorder; Carbamates; Chlordiazepoxide; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Lamotrigine; Lithium Chloride; Male; Motor Activity; Phenylenediamines; Rats; Rats, Wistar; Triazines	2008
Antiepileptogenic and antiictogenic effects of retigabine under conditions of rapid kindling: an ontogenic study. Epilepsia, 2008, Volume: 49, Issue:10 Topics: Aging; Animals; Animals, Newborn; Anticonvulsants; Behavior, Animal; Carbamates; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Electroencephalography; Epilepsy; Hippocampus; Kindling, Neurologic; Male; Motor Activity; Phenylenediamines; Rats; Rats, Wistar; Time Factors	2008
Effects of retigabine (D-23129) on different patterns of epileptiform activity induced by low magnesium in rat entorhinal cortex hippocampal slices. Epilepsia, 2000, Volume: 41, Issue:1 Topics: Animals; Anticonvulsants; Carbamates; Disease Models, Animal; Electroencephalography; Entorhinal Cortex; Epilepsy; Hippocampus; Magnesium Deficiency; Phenylenediamines; Rats; Rats, Wistar	2000