Page last updated: 2024-09-03

ezogabine and Abdominal Epilepsy

ezogabine has been researched along with Abdominal Epilepsy in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (11.11)29.6817
2010's24 (88.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berry, NS; Crean, CS; Reeve, R; Tompson, DJ1
Biton, V; Brodie, MJ; Derossett, SE; Gil-Nagel, A; Nohria, V1
Biton, V; DeRossett, S; Nohria, V; Partiot, A; Porter, RJ; Rosenfeld, WE; Sachdeo, R; Tompson, D1
Brandt, C; Daniluk, J; DeRossett, S; Edwards, S; Lerche, H; Lotay, N1
Brodie, MJ1
Elger, CE; Graf, W; Hamer, HM; Kasper, B; Kull, A; Kurth, C; Nass, RD; Rosenow, F; Steinhoff, BJ; Strzelczyk, A; Surges, R1
Kwan, P; Lim, KS; Lotay, N; White, R1
Brodie, MJ; Elger, C; Gil-Nagel, A; Hall, S; Lerche, H; Mansbach, H; Nohria, V; Shin, P1
Owen, RT1
Abou-Khalil, BW; French, JA; Hall, S; Leroy, RF; Mansbach, H; Nohria, V; Shin, P; Yacubian, EM1
Grippon, S; Kirkpatrick, P; Stafstrom, CE1
Brickel, N; DeRossett, S; Gandhi, P; Hammond, J; VanLandingham, K1
Burdette, DE; DeRossett, SE; Gil-Nagel, A; Hall, ST; Porter, RJ; Shaikh, S; White, R1
Rheims, S; Ryvlin, P1
Hecht, B1
Brodie, MJ; Castiglia, M; Cyr, T; Gil-Nagel, A; Hall, S; Leroy, R; Twomey, C; VanLandingham, K1
Cooper, J; Duffy, S; Glanville, J; Hugel, P; Lane, PW; Martyn-St James, M; McCool, R1
Splinter, MY1
Welty, TE; Yamada, M1
Craig, D; Fox, D; Paton, F; Rice, S; Woolacott, N1
Crean, CS; Tompson, DJ1
Forsgren, L; Kristian, B; Stefan, F; Wachtmeister, K1
Plosker, GL; Scott, LJ1
Alves, WM; Nohria, V; Partiot, A; Porter, RJ; Sachdeo, R1
Ebner, A; Höhling, J; Köhling, R; Pannek, H; Rundfeldt, C; Speckmann, E; Straub, H; Tuxhorn, I; Wolf, P1

Reviews

10 review(s) available for ezogabine and Abdominal Epilepsy

ArticleYear
Practical Use of Newer Antiepileptic Drugs as Adjunctive Therapy in Focal Epilepsy.
    CNS drugs, 2015, Volume: 29, Issue:11

    Topics: Acetamides; Adult; Aged; Animals; Anticonvulsants; Carbamates; Dibenzazepines; Drug Resistant Epilepsy; Epilepsies, Partial; Female; Humans; Lacosamide; Male; Middle Aged; Nitriles; Phenylenediamines; Pyridones

2015
Ezogabine: a novel antiepileptic as adjunctive therapy for partial onset seizures.
    Drugs of today (Barcelona, Spain : 1998), 2010, Volume: 46, Issue:11

    Topics: Animals; Anticonvulsants; Carbamates; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Interactions; Epilepsies, Partial; Humans; Phenylenediamines; Time Factors

2010
The urinary safety profile and secondary renal effects of retigabine (ezogabine): a first-in-class antiepileptic drug that targets KCNQ (K(v)7) potassium channels.
    Epilepsia, 2012, Volume: 53, Issue:4

    Topics: Animals; Anticonvulsants; Carbamates; Epilepsies, Partial; Humans; KCNQ Potassium Channels; Muscle, Smooth; Phenylenediamines; Urinary Retention

2012
Retigabine for partial onset seizures.
    Expert review of neurotherapeutics, 2012, Volume: 12, Issue:5

    Topics: Animals; Anticonvulsants; Carbamates; Disease Models, Animal; Epilepsies, Partial; Humans; Phenylenediamines; Randomized Controlled Trials as Topic; Treatment Outcome

2012
[Retigabine. A novel anticonvulsant drug for the adjunctive treatment of partial seizures].
    Medizinische Monatsschrift fur Pharmazeuten, 2012, Volume: 35, Issue:5

    Topics: Animals; Anticonvulsants; Carbamates; Clinical Trials, Phase III as Topic; Epilepsies, Partial; Humans; Phenylenediamines; Potassium Channel Blockers

2012
The efficacy and safety of retigabine and other adjunctive treatments for refractory partial epilepsy: a systematic review and indirect comparison.
    Seizure, 2012, Volume: 21, Issue:9

    Topics: Anticonvulsants; Carbamates; Disorders of Excessive Somnolence; Epilepsies, Partial; Humans; Phenylenediamines; Randomized Controlled Trials as Topic; Treatment Outcome

2012
Ezogabine (retigabine) and its role in the treatment of partial-onset seizures: a review.
    Clinical therapeutics, 2012, Volume: 34, Issue:9

    Topics: Animals; Anticonvulsants; Carbamates; Dose-Response Relationship, Drug; Drug Interactions; Epilepsies, Partial; Humans; Phenylenediamines; Potassium Channels, Voltage-Gated

2012
Ezogabine: an evaluation of its efficacy and safety as adjunctive therapy for partial-onset seizures in adults.
    The Annals of pharmacotherapy, 2012, Volume: 46, Issue:10

    Topics: Adult; Animals; Anticonvulsants; Carbamates; Drug Interactions; Epilepsies, Partial; Humans; Phenylenediamines; Treatment Outcome

2012
Retigabine for the adjunctive treatment of adults with partial-onset seizures in epilepsy with and without secondary generalization : a NICE single technology appraisal.
    PharmacoEconomics, 2013, Volume: 31, Issue:2

    Topics: Adolescent; Adult; Anticonvulsants; Carbamates; Cost-Benefit Analysis; Decision Support Techniques; Drug Industry; Epilepsies, Partial; Humans; Models, Theoretical; Phenylenediamines; Randomized Controlled Trials as Topic; Seizures; Young Adult

2013
Clinical pharmacokinetics of retigabine/ezogabine.
    Current clinical pharmacology, 2013, Volume: 8, Issue:4

    Topics: Age Factors; Aged; Anticonvulsants; Biological Availability; Carbamates; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Interactions; Epilepsies, Partial; Half-Life; Humans; Liver Diseases; Phenylenediamines; Renal Insufficiency

2013

Trials

10 trial(s) available for ezogabine and Abdominal Epilepsy

ArticleYear
Efficacy and tolerability exposure-response relationship of retigabine (ezogabine) immediate-release tablets in patients with partial-onset seizures.
    Clinical therapeutics, 2013, Volume: 35, Issue:8

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamates; Disorders of Excessive Somnolence; Dizziness; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Epilepsies, Partial; Female; Gait Disorders, Neurologic; Humans; Male; Middle Aged; Phenylenediamines; Tablets; Treatment Outcome; Young Adult

2013
Safety and tolerability of different titration rates of retigabine (ezogabine) in patients with partial-onset seizures.
    Epilepsy research, 2013, Volume: 107, Issue:1-2

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamates; Dose-Response Relationship, Drug; Double-Blind Method; Epilepsies, Partial; Female; Humans; Male; Middle Aged; Phenylenediamines; Treatment Outcome

2013
A novel design for a dose finding, safety, and drug interaction study of an antiepileptic drug (retigabine) in early clinical development.
    International journal of clinical pharmacology and therapeutics, 2014, Volume: 52, Issue:6

    Topics: Adolescent; Adult; Anticonvulsants; Carbamates; Drug Administration Schedule; Drug Dosage Calculations; Drug Interactions; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy, Generalized; Female; Humans; Male; Maximum Tolerated Dose; Middle Aged; Patient Safety; Phenylenediamines; Research Design; Risk Assessment; Time Factors; Treatment Outcome; United States; Young Adult

2014
Efficacy and safety of ezogabine/retigabine as adjunctive therapy to specified single antiepileptic medications in an open-label study of adults with partial-onset seizures.
    Seizure, 2015, Volume: 30

    Topics: Aged; Anticonvulsants; Carbamates; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsies, Partial; Female; Humans; Kaplan-Meier Estimate; Lamotrigine; Levetiracetam; Male; Middle Aged; Oxcarbazepine; Phenylenediamines; Piracetam; Seizures; Treatment Outcome; Triazines; Valproic Acid

2015
Efficacy and safety of retigabine/ezogabine as adjunctive therapy in adult Asian patients with drug-resistant partial-onset seizures: A randomized, placebo-controlled Phase III study.
    Epilepsy & behavior : E&B, 2016, Volume: 61

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamates; Double-Blind Method; Drug Resistant Epilepsy; Epilepsies, Partial; Female; Humans; Male; Middle Aged; Phenylenediamines; Seizures; Skin Pigmentation; Treatment Outcome; Young Adult

2016
Efficacy and safety of adjunctive ezogabine (retigabine) in refractory partial epilepsy.
    Neurology, 2010, Nov-16, Volume: 75, Issue:20

    Topics: Adult; Anticonvulsants; Carbamates; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Epilepsies, Partial; Female; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Phenylenediamines; Prospective Studies; Treatment Outcome

2010
Randomized, double-blind, placebo-controlled trial of ezogabine (retigabine) in partial epilepsy.
    Neurology, 2011, May-03, Volume: 76, Issue:18

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamates; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Epilepsies, Partial; Female; Humans; Male; Middle Aged; Phenylenediamines; Treatment Outcome

2011
Retigabine as adjunctive therapy in adults with partial-onset seizures: integrated analysis of three pivotal controlled trials.
    Epilepsy research, 2012, Volume: 101, Issue:1-2

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamates; Double-Blind Method; Endpoint Determination; Epilepsies, Partial; Female; Humans; Male; Middle Aged; Phenylenediamines; Treatment Outcome; Vital Signs; Young Adult

2012
Safety and efficacy of ezogabine (retigabine) in adults with refractory partial-onset seizures: Interim results from two ongoing open-label studies.
    Epilepsy research, 2012, Volume: 102, Issue:1-2

    Topics: Adult; Anticonvulsants; Carbamates; Dizziness; Drug Resistance; Epilepsies, Partial; Fatigue; Female; Headache; Humans; Male; Middle Aged; Phenylenediamines; Sleep Stages; Time; Treatment Outcome; Young Adult

2012
Randomized, multicenter, dose-ranging trial of retigabine for partial-onset seizures.
    Neurology, 2007, Apr-10, Volume: 68, Issue:15

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Australia; Carbamates; Dose-Response Relationship, Drug; Epilepsies, Partial; Europe; Female; Humans; Male; Middle Aged; Phenylenediamines; Risk Assessment; Risk Factors; Treatment Outcome; United States

2007

Other Studies

7 other study(ies) available for ezogabine and Abdominal Epilepsy

ArticleYear
Ezogabine (Potiga) toxicity.
    The Medical letter on drugs and therapeutics, 2013, Nov-25, Volume: 55, Issue:1430

    Topics: Adult; Anticonvulsants; Carbamates; Drug Labeling; Epilepsies, Partial; Humans; Phenylenediamines; United States; United States Food and Drug Administration

2013
Adjunctive retigabine in refractory focal epilepsy: Postmarketing experience at four tertiary epilepsy care centers in Germany.
    Epilepsy & behavior : E&B, 2016, Volume: 56

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamates; Child; Death, Sudden, Cardiac; Drug Resistant Epilepsy; Electrocardiography; Epilepsies, Partial; Female; Germany; Humans; Incidence; Male; Middle Aged; Phenylenediamines; Product Surveillance, Postmarketing; Retrospective Studies; Seizures; Tertiary Care Centers; Treatment Outcome; Young Adult

2016
Ezogabine (retigabine).
    Nature reviews. Drug discovery, 2011, 09-30, Volume: 10, Issue:10

    Topics: Animals; Anticonvulsants; Carbamates; Epilepsies, Partial; Humans; Phenylenediamines; Randomized Controlled Trials as Topic

2011
Ezogabine (Potiga) for epilepsy.
    The Medical letter on drugs and therapeutics, 2012, Aug-20, Volume: 54, Issue:1397

    Topics: Administration, Oral; Adult; Anticonvulsants; Carbamates; Drug Interactions; Epilepsies, Partial; Humans; Phenylenediamines

2012
Retigabine as add-on treatment of refractory epilepsy--a cost-utility study in a Swedish setting.
    Acta neurologica Scandinavica, 2013, Volume: 127, Issue:6

    Topics: Acetamides; Adult; Anticonvulsants; Carbamates; Cost-Benefit Analysis; Drug Therapy, Combination; Epilepsies, Partial; Health Care Costs; Humans; Lacosamide; Phenylenediamines; Quality-Adjusted Life Years; Sensitivity and Specificity; Sweden

2013
Retigabine: in partial seizures.
    CNS drugs, 2006, Volume: 20, Issue:7

    Topics: Animals; Anticonvulsants; Carbamates; Epilepsies, Partial; Humans; Phenylenediamines

2006
Effects of retigabine on rhythmic synchronous activity of human neocortical slices.
    Epilepsy research, 2001, Volume: 44, Issue:2-3

    Topics: Action Potentials; Adolescent; Adult; Anticonvulsants; Bicuculline; Carbamates; Child; Child, Preschool; Epilepsies, Partial; Female; GABA Antagonists; Humans; Magnesium; Male; Neocortex; Phenylenediamines

2001