Page last updated: 2024-09-04

ezetimibe and Gallstones

ezetimibe has been researched along with Gallstones in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (22.22)29.6817
2010's11 (61.11)24.3611
2020's3 (16.67)2.80

Authors

AuthorsStudies
Gu, A; Hu, H; Jiang, Z; Shao, W; Shen, W; Wang, B; Wang, Q; Zhao, G1
Fu, Z; Han, T; Hong, H; Hu, T; Lv, Y; Wang, S1
Arrese, M; Bizama, C; Espinoza, JA; Ferreccio, C; García, P; Gómez, N; González, X; Guevara, F; Kalergis, AM; Lobos-González, L; Miquel, JF; Muñoz-Durango, N; Roa, JC; Rosa, L; Saavedra, N; Villegas, J; Wichmann, IA1
Desai, S; E, S; Gangadharappa, HV; Krishna, KL; Mehdi, S; Shreyas, A; Srikanth, MS1
de Bari, O; Garruti, G; Liu, KJ; Neuschwander-Tetri, BA; Portincasa, P; Wang, DQ; Wang, HH1
de Bari, O; Liu, M; Paik, CN; Portincasa, P; Wang, DQ; Wang, HH1
Frikke-Schmidt, R; Lauridsen, BK; Nordestgaard, BG; Stender, S; Tybjærg-Hansen, A1
Kanno, K; Kishikawa, N; Mizooka, M; Sugiyama, A; Tazuma, S; Yokobayashi, K1
Floreani, A1
Amigo, L; Arrese, M; Azocar, L; Jarufe, N; Lammert, F; Miquel, JF; Molina, H; Nervi, F; Pimentel, F; Zúñiga, S1
Ahmed, MH1
Bonfrate, L; Di Ciaula, A; Portincasa, P; Wang, DQ; Wang, HH1
Ahmed, MH; Byrne, CD1
Jiang, ZY; Parini, P; Pramfalk, C1
Ganotakis, ES; Lioudaki, E; Mikhailidis, DP1
Andrade, JD; Carey, MC; Fox, JG; Kotecha, VR; Xie, M1
Gangopadhyay, A; Khadem, S; Moser, JA; Ren, S; Uppal, H; Xie, W; Zhai, Y1
Mendez-Sanchez, N; Portincasa, P; Uribe, M; Wang, DQ; Wang, HH1

Reviews

6 review(s) available for ezetimibe and Gallstones

ArticleYear
Recent advances, novel targets and treatments for cholelithiasis; a narrative review.
    European journal of pharmacology, 2021, Oct-05, Volume: 908

    Topics: Bile; Cholesterol; Ezetimibe; Gallstones; Risk Factors

2021
Prevention of cholesterol gallstones by inhibiting hepatic biosynthesis and intestinal absorption of cholesterol.
    European journal of clinical investigation, 2013, Volume: 43, Issue:4

    Topics: Anticholesteremic Agents; Azetidines; Cholagogues and Choleretics; Cholesterol; Ezetimibe; Gallstones; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intestinal Absorption; Lipid Metabolism; Liver; Ursodeoxycholic Acid

2013
Targets for current pharmacologic therapy in cholesterol gallstone disease.
    Gastroenterology clinics of North America, 2010, Volume: 39, Issue:2

    Topics: Azetidines; Cholesterol; Cholinergic Antagonists; Ezetimibe; Gallstones; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intestinal Absorption; Treatment Outcome

2010
Potential therapeutic uses for ezetimibe beyond lowering LDL-c to decrease cardiovascular events.
    Diabetes, obesity & metabolism, 2010, Volume: 12, Issue:11

    Topics: Anticholesteremic Agents; Atherosclerosis; Azetidines; Cholesterol, LDL; Clinical Trials as Topic; Ezetimibe; Fatty Liver; Female; Gallstones; Humans; Intestinal Absorption; Male

2010
Hepatic Niemann-Pick C1-like 1.
    Current opinion in lipidology, 2011, Volume: 22, Issue:3

    Topics: Animals; Anticholesteremic Agents; Azetidines; Cholesterol; Ezetimibe; Fatty Liver; Gallstones; Gene Expression; Gene Expression Regulation; Humans; Intestinal Mucosa; Intestines; Liver; Membrane Proteins; Membrane Transport Proteins

2011
Lipid lowering drugs and gallstones: a therapeutic option?
    Current pharmaceutical design, 2011, Volume: 17, Issue:33

    Topics: Animals; Anti-Obesity Agents; Anticholesteremic Agents; Azetidines; Ezetimibe; Gallstones; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Lipids; Risk Factors

2011

Trials

1 trial(s) available for ezetimibe and Gallstones

ArticleYear
Effect of ezetimibe on the prevention and dissolution of cholesterol gallstones.
    Gastroenterology, 2008, Volume: 134, Issue:7

    Topics: Adult; Animals; Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 5; ATP Binding Cassette Transporter, Subfamily G, Member 8; ATP-Binding Cassette Transporters; Azetidines; Bile; Cholelithiasis; Cholesterol; Disease Models, Animal; Dose-Response Relationship, Drug; Ezetimibe; Female; Gallbladder Emptying; Gallstones; Humans; Intestinal Absorption; Lipoproteins; Male; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Middle Aged; RNA, Messenger; Sterol O-Acyltransferase; Sterol O-Acyltransferase 2; Time Factors

2008

Other Studies

11 other study(ies) available for ezetimibe and Gallstones

ArticleYear
Dietary diosgenin transcriptionally down-regulated intestinal NPC1L1 expression to prevent cholesterol gallstone formation in mice.
    Journal of biomedical science, 2023, Jun-27, Volume: 30, Issue:1

    Topics: Animals; Caco-2 Cells; Cholesterol; Diet; Diosgenin; Ezetimibe; Gallstones; Humans; Intestines; Lipopolysaccharides; Liver; Male; Membrane Transport Proteins; Mice; Mice, Inbred C57BL

2023
Pioglitazone prevents cholesterol gallstone formation through the regulation of cholesterol homeostasis in guinea pigs with a lithogenic diet.
    Lipids in health and disease, 2019, Dec-11, Volume: 18, Issue:1

    Topics: Animals; Anticholesteremic Agents; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Cholesterol, Dietary; Diet; Ezetimibe; Gallbladder; Gallstones; Guinea Pigs; Homeostasis; Hydroxymethylglutaryl CoA Reductases; Hypoglycemic Agents; Liver; Male; Pioglitazone; Sterol Regulatory Element Binding Protein 2

2019
Evaluation of the chemopreventive potentials of ezetimibe and aspirin in a novel mouse model of gallbladder preneoplasia.
    Molecular oncology, 2020, Volume: 14, Issue:11

    Topics: Animals; Aspirin; Chemoprevention; Cholecystolithiasis; Cholesterol; Cholesterol, Dietary; Chronic Disease; Diet; Disease Models, Animal; Disease Progression; Ezetimibe; Fatty Liver; Feeding Behavior; Gallbladder Neoplasms; Gallstones; Inflammation; Male; Metaplasia; Mice, Inbred C57BL; Precancerous Conditions; Spleen

2020
Ezetimibe prevents the formation of oestrogen-induced cholesterol gallstones in mice.
    European journal of clinical investigation, 2014, Volume: 44, Issue:12

    Topics: Animals; Anticholesteremic Agents; Azetidines; Bile Acids and Salts; Biliary Tract; Cholesterol; Estradiol; Estrogens; Ezetimibe; Female; Gallstones; Intestinal Absorption; Lipid Metabolism; Male; Mice, Inbred AKR; RNA, Messenger

2014
Genetic variation in the cholesterol transporter NPC1L1, ischaemic vascular disease, and gallstone disease.
    European heart journal, 2015, Jul-01, Volume: 36, Issue:25

    Topics: Aged; Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 8; ATP-Binding Cassette Transporters; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Female; Gallstones; Genetic Variation; Genotype; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Ischemia; Lipid Metabolism; Male; Membrane Proteins; Membrane Transport Proteins; Mendelian Randomization Analysis; Middle Aged; Myocardial Infarction; Risk Factors; Stroke

2015
Long-term administration of a Niemann-Pick C1-like 1 inhibitor, ezetimibe, does not worsen bile lithogenicity in dyslipidemic patients with hepatobiliary diseases.
    Journal of hepato-biliary-pancreatic sciences, 2016, Volume: 23, Issue:2

    Topics: Anticholesteremic Agents; Bile; Cholesterol; Dyslipidemias; Ezetimibe; Fatty Liver; Female; Gallstones; Humans; Lipid Metabolism; Lipoproteins; Male; Middle Aged; Phytosterols; Ursodeoxycholic Acid

2016
A novel approach for prevention and dissolution of cholesterol gallstones.
    Liver international : official journal of the International Association for the Study of the Liver, 2008, Volume: 28, Issue:7

    Topics: Animals; Anticholesteremic Agents; Azetidines; Cholesterol; Disease Models, Animal; Ezetimibe; Gallstones; Humans

2008
Ezetimibe prevents cholesterol gallstone formation in mice.
    Liver international : official journal of the International Association for the Study of the Liver, 2008, Volume: 28, Issue:7

    Topics: Animals; Anticholesteremic Agents; Azetidines; CD36 Antigens; Cholesterol; Cholesterol, Dietary; Disease Models, Animal; Duodenum; Ezetimibe; Female; Gallstones; Gene Expression; Humans; Intestinal Absorption; Liver; Male; Membrane Proteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL

2008
Ezetimbe as potential treatment for cholesterol gallstones: the need for clinical trials.
    World journal of gastroenterology, 2010, Apr-07, Volume: 16, Issue:13

    Topics: Animals; Anticholesteremic Agents; Azetidines; Cholesterol; Clinical Trials as Topic; Diet; Drug Evaluation, Preclinical; Ezetimibe; Fatty Liver; Gallstones; Humans; Insulin Resistance; Intestine, Small

2010
Augmented cholesterol absorption and sarcolemmal sterol enrichment slow small intestinal transit in mice, contributing to cholesterol cholelithogenesis.
    The Journal of physiology, 2012, Apr-15, Volume: 590, Issue:8

    Topics: Animals; Azetidines; Bile; Bile Acids and Salts; Biological Transport; Cholecystokinin; Cholesterol; Cholic Acid; Diet, High-Fat; Ezetimibe; Female; Gallbladder; Gallstones; Gastrointestinal Transit; Helicobacter hepaticus; Helicobacter Infections; Intestinal Absorption; Intestine, Small; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Myocytes, Smooth Muscle; Sarcolemma; Sterols

2012
Activation of liver X receptor sensitizes mice to gallbladder cholesterol crystallization.
    Hepatology (Baltimore, Md.), 2008, Volume: 47, Issue:4

    Topics: Animals; Anticholesteremic Agents; Azetidines; Bile Acids and Salts; Cholecystitis; Cholesterol; Crystallization; Diet; DNA-Binding Proteins; Ezetimibe; Female; Gallbladder; Gallstones; Gene Expression Profiling; Intestinal Mucosa; Lipid Metabolism; Liver; Liver X Receptors; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Orphan Nuclear Receptors; Phospholipids; Receptors, Cytoplasmic and Nuclear; Receptors, LDL

2008