Page last updated: 2024-09-04

ezetimibe and Fatty Liver, Nonalcoholic

ezetimibe has been researched along with Fatty Liver, Nonalcoholic in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's26 (78.79)24.3611
2020's7 (21.21)2.80

Authors

AuthorsStudies
Canet, MJ; Cherrington, NJ; Fisher, CD; Hardwick, RN; Street, SM1
Farrell, GC; Horn, CL; Ioannou, GN; Morales, AL; Savard, C1
Bae, JH; Chang, Y; Jang, JY; Jeong, SW; Kim, HS; Kim, SG; Kim, YS; Lee, SH; Lee, WM; Moon, JE; Yoo, JJ1
Averna, M; Cabibbi, D; Caldarella, R; Cefalù, AB; Ciaccio, M; Craxi, A; Giammanco, A; Muratore, R; Noto, D; Petta, S; Porcasi, R; Spina, R1
Cha, BS; Cho, Y; Choi, JY; Kang, ES; Kim, YE; Lee, BW; Lee, M; Lee, YH; Rhee, H1
Chung, KS; Gee, HY; Kim, DY; Park, JY1
Athyros, VG; Doumas, M; Imprialos, K; Stavropoulos, K1
Fras, Z; Mikhailidis, DP1
Di Mauro, S; Di Pino, A; Ferrara, V; Filippello, A; Marchisello, S; Piro, S; Purrello, F; Rabuazzo, AM; Scamporrino, A; Scicali, R; Urbano, F1
Ahn, H; Cheung, RC; Jun, DW; Kim, HJ; Lee, HY; Nguyen, MH; Oh, H; Saeed, WK1
Blazing, M; Cannon, CP; Chung, RT; Corey, KE; Giugliano, RP; O'Donoghue, ML; Park, JG; Simon, TG1
Pitha, J1
Cheon, GJ; Jun, BG1
Farrell, GC; Gan, LT; Haigh, WG; Ioannou, G; Larter, CZ; Teoh, NC; Van Rooyen, DM; Yeh, MM1
Arai, K; Honda, M; Kaneko, S; Kato, K; Kita, Y; Misu, H; Mizukoshi, E; Nakamura, M; Ota, T; Sunagozaka, H; Takamura, T; Takeshita, Y; Yamada, K; Yamashita, T; Zen, Y1
Musso, G1
Guo, Y; Liang, Y; Liu, S; Ren, Q; Wang, X; Wu, T1
Ang, B; Bettencourt, R; Bhatt, A; Brenner, DA; Ehman, R; Haufe, W; Hernandez, L; Hooker, C; Hooker, J; Jain, R; Kono, Y; Lin, GY; Loomba, R; Nguyen, P; Noureddin, M; Richards, L; Salotti, J; Sirlin, CB; Soaft, L; Valasek, MA; Yin, M1
Farrell, GC; Haigh, WG; Ioannou, GN; Savard, C; Teoh, NC; Van Rooyen, DM; Yeh, MM1
Eguchi, Y; Fujita, K; Honda, Y; Hyogo, H; Imajo, K; Kessoku, T; Kirikoshi, H; Mawatari, H; Nakajima, A; Nozaki, Y; Ogawa, Y; Ono, M; Saito, S; Sumida, Y; Taguri, M; Tomeno, W; Wada, K; Yoneda, M1
Averna, M1
Drozd, VIu; Haĭdychuk, VS; Khukhlina, OS; Kosar, LIu; Mandryk, OIe1
Bae, SH; Cha, BS; Chun, Y; Han, DH; Jeong, H; Ji, HW; Kim, G; Kim, J; Kim, SH; Komatsu, M; Lee, DH; Lee, HY; Lee, JS; Lee, M; Lee, MJ; Lee, YH; Lee, YS; Min, BS; Nam, KT; Park, JS; Sung, SH1
Chung, RT; Corey, KE; Giugliano, R; Simon, TG1
Ahn, SC; Jang, HJ; Jeon, TI; Kim, KY; Osborne, TF; Park, KI; Seo, J; Seo, YK; Shin, IW; Suh, PG; Yang, YR1
Bettencourt, R; Hamilton, G; Heba, E; Lin, GY; Lin, SC; Loomba, R; Lunde, O; Sirlin, CB; Valasek, MA1
Gao, X; Jacobs, RL; Kassiri, Z; Lingrell, S; Takawale, A; van der Veen, JN; Vance, DE1
Fukui, M; Hasegawa, G; Itoh, Y; Minami, M; Mitsuyoshi, H; Nakamura, N; Obayashi, H; Ohta, M; Okanoue, T; Park, H; Shima, T; Yamaguchi, K; Yasui, K; Yoshikawa, T1
Yoshida, M1
Fujita, K; Imajo, K; Kirikoshi, H; Mawatari, H; Nakajima, A; Saito, S; Yoneda, M1
Gotoh, T; Hashimoto, M; Kawanami, Y; Moritani, A; Shiwa, T; Yokoyama, T1
Cassader, M; Gambino, R; Musso, G1
Fujisawa, K; Kuwashiro, S; Matsumoto, T; Nishina, H; Oishi, T; Sakaida, I; Terai, S1

Reviews

7 review(s) available for ezetimibe and Fatty Liver, Nonalcoholic

ArticleYear
Role of Cholesterol-Associated Steatohepatitis in the Development of NASH.
    Hepatology communications, 2022, Volume: 6, Issue:1

    Topics: Animals; Anticholesteremic Agents; Cholesterol; Cholesterol, Dietary; Ezetimibe; Fatty Liver; Homeostasis; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Non-alcoholic Fatty Liver Disease; Risk Factors

2022
What Does the Future Hold for Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis?
    Current vascular pharmacology, 2019, Volume: 17, Issue:5

    Topics: Anticholesteremic Agents; Diffusion of Innovation; Drug Therapy, Combination; Ezetimibe; Forecasting; Gastroenterology; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Liver; Non-alcoholic Fatty Liver Disease; Prevalence; Risk Factors; Risk Reduction Behavior; Treatment Outcome

2019
Ezetimibe decreased nonalcoholic fatty liver disease activity score but not hepatic steatosis.
    The Korean journal of internal medicine, 2019, Volume: 34, Issue:2

    Topics: Anticholesteremic Agents; Ezetimibe; Humans; Non-alcoholic Fatty Liver Disease; Severity of Illness Index

2019
The effect of ezetimibe on NAFLD.
    Atherosclerosis. Supplements, 2015, Volume: 17

    Topics: Animals; Anticholesteremic Agents; Azetidines; Drug Therapy, Combination; Ezetimibe; Humans; Lipid Metabolism; Liver; Non-alcoholic Fatty Liver Disease; Treatment Outcome

2015
Cardiovascular Risk Reduction in Patients with Nonalcoholic Fatty Liver Disease: The Potential Role of Ezetimibe.
    Digestive diseases and sciences, 2016, Volume: 61, Issue:12

    Topics: Anticholesteremic Agents; Atherosclerosis; Cardiovascular Diseases; Dyslipidemias; Endothelium, Vascular; Ezetimibe; Humans; Inflammation; Insulin Resistance; Intra-Abdominal Fat; Liver; Metabolic Syndrome; Non-alcoholic Fatty Liver Disease; Obesity; Obesity, Abdominal; Risk Reduction Behavior; Thrombophilia

2016
Novel role of NPC1L1 in the regulation of hepatic metabolism: potential contribution of ezetimibe in NAFLD/NASH treatment.
    Current vascular pharmacology, 2011, Volume: 9, Issue:1

    Topics: Animals; Anticholesteremic Agents; Azetidines; Cholesterol; Ezetimibe; Fatty Liver; Humans; Liver; Membrane Proteins; Membrane Transport Proteins; Metabolic Syndrome; Non-alcoholic Fatty Liver Disease

2011
Cholesterol-lowering therapy for the treatment of nonalcoholic fatty liver disease: an update.
    Current opinion in lipidology, 2011, Volume: 22, Issue:6

    Topics: Animals; Anticholesteremic Agents; Azetidines; Ezetimibe; Fatty Liver; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Non-alcoholic Fatty Liver Disease; Randomized Controlled Trials as Topic

2011

Trials

10 trial(s) available for ezetimibe and Fatty Liver, Nonalcoholic

ArticleYear
Effect of Nutrition Education in NAFLD Patients Undergoing Simultaneous Hyperlipidemia Pharmacotherapy: A Randomized Controlled Trial.
    Nutrients, 2021, Dec-13, Volume: 13, Issue:12

    Topics: Adult; Alanine Transaminase; Ezetimibe; Female; Health Education; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Liver Cirrhosis; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Nutrition Therapy; Nutritional Sciences; Prospective Studies; Republic of Korea

2021
Lifestyle versus ezetimibe plus lifestyle in patients with biopsy-proven non-alcoholic steatohepatitis (LISTEN): A double-blind randomised placebo-controlled trial.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2022, Volume: 32, Issue:5

    Topics: Biopsy; Double-Blind Method; Ezetimibe; Humans; Life Style; Non-alcoholic Fatty Liver Disease; Treatment Outcome

2022
Ezetimibe combination therapy with statin for non-alcoholic fatty liver disease: an open-label randomized controlled trial (ESSENTIAL study).
    BMC medicine, 2022, 03-21, Volume: 20, Issue:1

    Topics: Diabetes Mellitus, Type 2; Elasticity Imaging Techniques; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Non-alcoholic Fatty Liver Disease

2022
Have We Learnt all from IMPROVE-IT? Part I. Core Results and Subanalyses on the Effects of Ezetimibe Added to Statin Therapy Related to Age, Gender and Selected Chronic Diseases (Kidney Disease, Diabetes Mellitus and Non-Alcoholic Fatty Liver Disease).
    Current vascular pharmacology, 2021, Volume: 19, Issue:5

    Topics: Aged; Anticholesteremic Agents; Chronic Disease; Diabetes Mellitus; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Diseases; Male; Non-alcoholic Fatty Liver Disease; Simvastatin; Treatment Outcome

2021
The nonalcoholic fatty liver disease (NAFLD) fibrosis score, cardiovascular risk stratification and a strategy for secondary prevention with ezetimibe.
    International journal of cardiology, 2018, Nov-01, Volume: 270

    Topics: Aged; Anticholesteremic Agents; Cardiovascular Diseases; Ezetimibe; Female; Humans; Internationality; Liver Cirrhosis; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Prospective Studies; Risk Factors; Secondary Prevention; Severity of Illness Index

2018
The effects of ezetimibe on non-alcoholic fatty liver disease and glucose metabolism: a randomised controlled trial.
    Diabetologia, 2014, Volume: 57, Issue:5

    Topics: Aged; Anticholesteremic Agents; Area Under Curve; Azetidines; Biopsy; Carnitine; Cholesterol; Ezetimibe; Fatty Acids; Female; Fibrosis; Gene Expression Profiling; Glucose; Glucose Clamp Technique; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Insulin; Liver; Male; Middle Aged; Myofibroblasts; Non-alcoholic Fatty Liver Disease; Oligonucleotide Array Sequence Analysis; Signal Transduction; Transaminases; Treatment Outcome

2014
Ezetimibe for the treatment of nonalcoholic steatohepatitis: assessment by novel magnetic resonance imaging and magnetic resonance elastography in a randomized trial (MOZART trial).
    Hepatology (Baltimore, Md.), 2015, Volume: 61, Issue:4

    Topics: Anticholesteremic Agents; Azetidines; Double-Blind Method; Elasticity Imaging Techniques; Ezetimibe; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Non-alcoholic Fatty Liver Disease

2015
LDL-migration index (LDL-MI), an indicator of small dense low-density lipoprotein (sdLDL), is higher in non-alcoholic steatohepatitis than in non-alcoholic fatty liver: a multicenter cross-sectional study.
    PloS one, 2014, Volume: 9, Issue:12

    Topics: Adult; Anticholesteremic Agents; Atherosclerosis; Atorvastatin; Azetidines; Cross-Sectional Studies; Ezetimibe; Female; Heptanoic Acids; Humans; Lipoproteins, LDL; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Pyrroles; Risk Factors

2014
Assessment of treatment response in non-alcoholic steatohepatitis using advanced magnetic resonance imaging.
    Alimentary pharmacology & therapeutics, 2017, Volume: 45, Issue:6

    Topics: Adult; Aged; Anticholesteremic Agents; Biomarkers; Cross-Sectional Studies; Diet, Fat-Restricted; Double-Blind Method; Ezetimibe; Female; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Treatment Outcome

2017
Efficacy of long-term ezetimibe therapy in patients with nonalcoholic fatty liver disease.
    Journal of gastroenterology, 2011, Volume: 46, Issue:1

    Topics: Adult; Anticholesteremic Agents; Azetidines; Biomarkers; Biopsy; Drug Administration Schedule; Ezetimibe; Fatty Liver; Female; Humans; Liver; Liver Cirrhosis; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Treatment Outcome

2011

Other Studies

16 other study(ies) available for ezetimibe and Fatty Liver, Nonalcoholic

ArticleYear
Molecular mechanism of altered ezetimibe disposition in nonalcoholic steatohepatitis.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:3

    Topics: Animals; Anticholesteremic Agents; Azetidines; Bile Acids and Salts; Biliary Tract; Biological Transport; Choline Deficiency; Diet; Ezetimibe; Fatty Liver; Glucuronosyltransferase; Intestinal Mucosa; Liver; Male; Membrane Transport Proteins; Methionine; Multidrug Resistance-Associated Proteins; Non-alcoholic Fatty Liver Disease; Rats; Rats, Sprague-Dawley

2012
Preventive effect of empagliflozin and ezetimibe on hepatic steatosis in adults and murine models.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 161

    Topics: Adult; Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Ezetimibe; Glucose; Humans; Liver; Mice; Non-alcoholic Fatty Liver Disease

2023
Analysis of steatosis biomarkers and inflammatory profile after adding on PCSK9 inhibitor treatment in familial hypercholesterolemia subjects with nonalcoholic fatty liver disease: A single lipid center real-world experience.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2021, 03-10, Volume: 31, Issue:3

    Topics: Aged; Anticholesteremic Agents; Biomarkers; Blood Glucose; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Inflammation Mediators; Italy; Lipids; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; PCSK9 Inhibitors; Prospective Studies; Serine Proteinase Inhibitors; Time Factors; Treatment Outcome; Triglycerides

2021
Improved management of patients after acute coronary syndrome: using nonalcoholic fatty liver disease fibrosis score and ezetimibe?
    International journal of cardiology, 2018, 11-01, Volume: 270

    Topics: Acute Coronary Syndrome; Azetidines; Ezetimibe; Humans; Liver; Liver Cirrhosis; Non-alcoholic Fatty Liver Disease

2018
The utility of ezetimibe therapy in nonalcoholic fatty liver disease.
    The Korean journal of internal medicine, 2019, Volume: 34, Issue:2

    Topics: Ezetimibe; Humans; Liver; Non-alcoholic Fatty Liver Disease

2019
Pharmacological cholesterol lowering reverses fibrotic NASH in obese, diabetic mice with metabolic syndrome.
    Journal of hepatology, 2013, Volume: 59, Issue:1

    Topics: Adiponectin; Animals; Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol; Diabetes Complications; Drug Therapy, Combination; Ezetimibe; Fatty Liver; Female; Heptanoic Acids; Insulin; Liver; MAP Kinase Signaling System; Metabolic Syndrome; Mice; Mice, Mutant Strains; Mice, Obese; Non-alcoholic Fatty Liver Disease; Pyrroles

2013
Ezetimibe in the balance: can cholesterol-lowering drugs alone be an effective therapy for NAFLD?
    Diabetologia, 2014, Volume: 57, Issue:5

    Topics: Anticholesteremic Agents; Azetidines; Ezetimibe; Female; Glucose; Humans; Male; Non-alcoholic Fatty Liver Disease

2014
Ezetimibe prevents the development of non‑alcoholic fatty liver disease induced by high‑fat diet in C57BL/6J mice.
    Molecular medicine reports, 2014, Volume: 10, Issue:6

    Topics: Acetyl-CoA Carboxylase; Animals; Anticholesteremic Agents; Azetidines; CD36 Antigens; Diet, High-Fat; Ezetimibe; Fatty Acids; Fibrosis; Hyperinsulinism; Insulin Resistance; Lipid Metabolism; Lipogenesis; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Stearoyl-CoA Desaturase

2014
Cholesterol-lowering drugs cause dissolution of cholesterol crystals and disperse Kupffer cell crown-like structures during resolution of NASH.
    Journal of lipid research, 2015, Volume: 56, Issue:2

    Topics: Animals; Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol; Ezetimibe; Female; Heptanoic Acids; Inflammasomes; Kupffer Cells; Liver; Mice; Mice, Mutant Strains; Non-alcoholic Fatty Liver Disease; Pyrroles

2015
[The use of complex tools ezetimibe, hepadyfu fosinopril and correction of blood pressure and endothelial dysfunction in patients with nonalcoholic steatohepatitis and essential hypertension stage II].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 2014, Volume: 67, Issue:2 Pt 2

    Topics: Adenine; Anticholesteremic Agents; Azetidines; Carnitine; Drug Combinations; Endothelium, Vascular; Essential Hypertension; Ezetimibe; Fosinopril; Humans; Hypertension; Non-alcoholic Fatty Liver Disease; Obesity; Vascular Diseases

2014
Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis.
    Free radical biology & medicine, 2016, Volume: 99

    Topics: AMP-Activated Protein Kinases; Animals; Antioxidants; Apoptosis; Diet; Ezetimibe; Gene Expression Regulation; Glutathione Transferase; Humans; Kelch-Like ECH-Associated Protein 1; Liver; Male; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Sequestosome-1 Protein; Signal Transduction

2016
SREBP-2/PNPLA8 axis improves non-alcoholic fatty liver disease through activation of autophagy.
    Scientific reports, 2016, 10-21, Volume: 6

    Topics: Animals; Anticholesteremic Agents; Autophagosomes; Autophagy; Cells, Cultured; Diet, High-Fat; Disease Models, Animal; Drug Therapy, Combination; Ezetimibe; Group VI Phospholipases A2; Hepatocytes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Signal Transduction; Sterol Regulatory Element Binding Protein 2; Triglycerides

2016
Fenofibrate, but not ezetimibe, prevents fatty liver disease in mice lacking phosphatidylethanolamine
    Journal of lipid research, 2017, Volume: 58, Issue:4

    Topics: Animals; Disease Models, Animal; Endoplasmic Reticulum Stress; Ezetimibe; Fenofibrate; Humans; Insulin Resistance; Lipid Metabolism; Lipoproteins, VLDL; Liver; Mice; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Obesity; Oxidation-Reduction; Phosphatidylethanolamine N-Methyltransferase; Triglycerides

2017
Induction of microsomal triglyceride transfer protein expression is a candidate mechanism by which ezetimibe therapy might exert beneficial effects in patients with nonalcoholic steatohepatitis.
    Journal of gastroenterology, 2011, Volume: 46, Issue:3

    Topics: Anticholesteremic Agents; Azetidines; Carrier Proteins; Ezetimibe; Fatty Liver; Humans; Non-alcoholic Fatty Liver Disease

2011
The efficacy of ezetimibe on nonalcoholic fatty liver disease (NAFLD).
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2011, Volume: 108, Issue:8

    Topics: Anticholesteremic Agents; Azetidines; Ezetimibe; Fatty Liver; Female; Humans; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Ultrasonography

2011
Ezetimibe reduces fatty acid quantity in liver and decreased inflammatory cell infiltration and improved NASH in medaka model.
    Biochemical and biophysical research communications, 2012, May-25, Volume: 422, Issue:1

    Topics: Animals; Anticholesteremic Agents; Azetidines; Disease Models, Animal; Ezetimibe; Fatty Acids; Fatty Liver; Inflammation; Liver; Non-alcoholic Fatty Liver Disease; Oryzias

2012