ezetimibe has been researched along with Elevated Cholesterol in 625 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 274 (43.84) | 29.6817 |
2010's | 281 (44.96) | 24.3611 |
2020's | 70 (11.20) | 2.80 |
Authors | Studies |
---|---|
Song, Z; Wang, X; Xing, D; Xue, J; Zhang, R | 1 |
Jiang, H; Liu, W; Meng, J; Wang, J; Xing, D; Zeng, J; Zhang, R | 1 |
Baratzadeh, F; Jamialahmadi, T; Reiner, Ž; Sahebkar, A; Santos, RD; Simental-Mendía, LE; Susekov, AV; Xu, S | 1 |
Blumenthal, RS; Braun, LT; Grundy, SM; Heidenreich, PA; Lloyd-Jones, D; Orringer, CE; Saseen, JJ; Smith, SC; Sperling, LS; Stone, NJ; Virani, SS | 1 |
Bacchin, ASF; Bianco, HT; Caixeta, A; Damasceno, NRT; Fonseca, FA; França, CN; Izar, MCO; Mello, APQ; Moreira, FT; Neto, AMF; Pinto, LCS; Póvoa, RMS | 1 |
Haidermota, S; Hoffmann, AP; Honigberg, MC; Natarajan, P; Newton, SL; Yu, Z | 1 |
Catapano, AL; Pirillo, A | 1 |
Adamson, SS; Biddinger, SB; Bullock, K; Chahar, S; Clish, CB; Crooke, RM; de Ferranti, SD; Gearing, ME; Graham, MJ; Hagey, LR; Kidambi, S; Krawczyk, J; Levenson, AE; Ling, AV; Miao, J; Semova, I; Shin, DJ; Vicent, D; Williams, KA | 1 |
Papachristou, S; Papanas, N; Popovic, DS; Stokic, E | 1 |
Burnett, H; Cichewicz, A; Di Domenico, M; Durand, A; Fahrbach, K; Jindal, R; Reichelt, A; Tarpey, J; Viljoen, A | 1 |
Joung, KH; Kang, SM; Kim, HJ; Kim, JM; Ku, BJ; Lee, JC | 2 |
Hamasaki, A; Hasebe, M; Honjo, S; Iwasaki, K; Iwasaki, Y; Keidai, Y | 1 |
Calabrò, P; De Ferrari, GM; Filardi, PP; Indolfi, C; Romeo, F | 1 |
Chao, TH; Chen, CP; Chou, MT; Hsieh, CH; Huang, CY; Jong, GP; Lee, IT; Lu, CH; McGirr, A; Sheu, WH | 1 |
Chen, J; Ding, C; Ge, J; Li, Z; Liu, Y; Qian, J; Ren, X; Shi, M; Yang, P; Zhang, X | 1 |
Chang, J; Han, N; Hu, X; Li, H; Li, J; Liang, B; Liu, W; Lu, C; Meng, J; Shi, L; Wang, C; Wang, X; Xing, D; Yang, S; Zeng, J; Zhang, R | 1 |
Ahn, JC; Cha, DH; Cho, EJ; Cho, JM; Choi, CU; Choi, SY; Gwon, HC; Han, KH; Han, KR; Hong, SJ; Hong, YJ; Jeong, HS; Jeong, YH; Jo, SH; Kang, HJ; Kim, BK; Kim, SH; Kim, WS; Lee, SY; Park, TH; Woo, SI | 1 |
Hu, YX; Jing, Q; Li, FF; Liang, C; Liang, YL; Qin, YW; You, HM; Zhao, XX; Zhu, RF | 1 |
Baum, SJ; Bilitou, A; Gillard, KK; Louie, MJ; McQueen, RB; Nash, B; Ray, KK; Sasiela, WJ; Shah, H | 1 |
Baum, SJ; Gaudet, D; Gencer, B; Kassahun, H; Knusel, B; Kuder, JF; Lepor, NE; López, JAG; Murphy, SA; O'Donoghue, ML; Ran, X; Rosenson, RS; Sabatine, MS; Stout, E; Wang, H; Wu, Y | 1 |
Ju, SH; Ku, BJ | 1 |
Campuzano Ruiz, R; Cosín-Sales, J; Díaz Díaz, JL; Escobar Cervantes, C; Fernández Olmo, MR; Gómez-Doblas, JJ; Mostaza, JM; Pedro-Botet, J; Plana Gil, N; Valdivielso, P | 1 |
Lin, Z; Yang, C; Zhong, Z | 1 |
Aker, A; Naoum, I; Saliba, W; Zafrir, B | 1 |
Landmesser, U; Sinning, D | 1 |
Garon, G; Liu, Y; Lv, Q; Ma, C; Mei, S; Su, Q; Wang, M; Wu, Y; Xu, L; Zhang, G | 1 |
Cho, JM; Choi, JY; Chun, SW; Chung, JW; Hong, SJ; Hong, YJ; Kim, BJ; Kim, CS; Kim, DH; Kim, HS; Kim, KS; Kim, SH; Kim, TN; Lee, CW; Lee, SA; Lee, SH; Lee, SR; Park, HC; Sung, JH; Yoon, SB | 1 |
Kim, HS; Kim, NH; Kim, SG; Kim, SS; Ko, SH; Lee, BK; Lee, I; Lee, JH; Moon, JS; Park, IR; Won, KC | 1 |
Leong, D; Wu, PE | 1 |
Kang, LN; Lan, RF; Wang, L; Xu, B; Xu, W; Zhang, XL; Zhang, XW | 1 |
Barge-Caballero, E; Barge-Caballero, G; Couto-Mallón, D; Crespo-Leiro, MG; Del Castillo-García, S; Groba-Marco, MDV | 1 |
Ahn, Y; Chae, IH; Han, KR; Hong, SJ; Hong, TJ; Jeon, DW; Jeon, HK; Kim, HS; Kim, HY; Kim, KJ; Kim, SH; Kim, W; Kwak, CH; Lee, N; Moon, KW; Nam, CW; Park, S; Park, TH; Rha, SW; Rhee, MY; Yoon, YW | 1 |
Cyrille, M; Inomata, H; Inoue, I; Kajinami, K; Koba, S; Lu, C; Shimauchi, J | 1 |
Pedro-Botet, J; Pintó, X | 1 |
Suzuki, H; Takada, T; Toyoda, Y; Yamanashi, Y | 1 |
Kong, Q; Li, M; Liang, C; Wang, Y; Yu, M | 1 |
Kawashiri, MA; Nomura, A; Okada, H; Tada, H; Takamura, M | 1 |
Lütjohann, D; Sijbrands, EJG; Weingärtner, O | 1 |
Almeida, JT; Esteves, AL; Martins, F; Palma, I | 1 |
Ahmed, ST; Akeroyd, JM; Ballantyne, CM; Dixon, DL; Gluckman, TJ; Jia, X; Nambi, V; Petersen, LA; Ramsey, DJ; Rifai, MA; Stone, NJ; Virani, SS | 1 |
Cicero, AFG; Fogacci, F; Strilchuk, L; Tocci, G | 1 |
Blom, DJ; Bouharati, C; Chilton, R; Ebrahim, IO; Karamchand, S; Leisegang, RF; Musa, MG; Naidoo, P; Raal, FJ; Rambiritch, V; Ranjith, N; Shunmoogam, N; Tonder, AV | 1 |
Choksi, RR; Goldfaden, RF; Lewis, T; Niman, S; Rana, K; Reid, J; Sheikh-Ali, M | 1 |
Scheen, AJ; Wallemacq, C | 1 |
Cho, L | 1 |
Bacalbasa, N; Bratu, OG; Crismaru, I; Diaconu, CC; Gaman, MA; Pantea Stoian, A; Stanescu, AMA | 1 |
Abdel-Salam, S; Al-Asaad, H; Aronson, R; Bajaj, HS; Brown, RE; Jiandani, D; Khandwala, H; Steen, O; Venn, K | 1 |
Huerín, M; Lobo, M; Masson, G; Masson, W; Molinero, G; Nogueira, JP; Siniawski, D | 1 |
Corsini, A; Ferri, N | 1 |
Dateki, S; Ikeda, K; Kashimada, K; Komiya, C; Mishima, H; Nakano, Y; Ogawa, Y; Shiba, K; Shimizu, H; Tsujimoto, K; Yamada, T; Yoshiura, KI | 1 |
Lamb, YN | 1 |
Hirano, S; Kawashiri, MA; Nomura, A; Tada, H; Takenaga, M; Tanaka, H; Watanabe, Y | 1 |
Chan, P; Lam, CWK; Tomlinson, B; Zhang, Y | 1 |
Khan, SA; Naz, A; Qamar Masood, M; Shah, R | 1 |
Dornstauder, E; Fraas, U; Katzmann, JL; Laufs, U; Smieszek, T; Sorio-Vilela, F; Zappacosta, S | 1 |
Cho, JH; Kim, H; Kim, HS; Kim, JH; Lee, H; Lee, J; Lee, SH; Yim, HW; Yoon, KH | 1 |
Fabiszak, T; Kasprzak, M; Krintus, M; Kubica, J; Obońska, K; Tymosiak, K | 1 |
Al Matrooshi, NO; Bhagavathula, AS; Clark, CCT; Rahmani, J | 2 |
Banach, M; Penson, PE | 1 |
Hanselman, JC; MacDougall, DE; Nicholls, SJ; Rubino, J; Sterling, LR | 1 |
Bea, AM; Benaiges, D; Blanco-Vaca, F; Brea-Hernando, Á; Climent, E; Pedro-Botet, J; Perea, V; Pintó, X; Plana, N; Suárez-Tembra, M | 1 |
Casula, M; Catapano, AL; Pirillo, A; Tokgözoğlu, L | 1 |
Suadoni, MT | 1 |
Diaconu, CC; Furtunescu, F; Iorga, RA; Katsiki, N; Rizzo, M; Stoian, AP | 1 |
Lekuona, I; Pintó, X | 1 |
Barrios, V; Escobar, C | 2 |
Amarenco, P; Bruckert, E; Charles, H; Giroud, M; Kim, JS; Labreuche, J; Lavallée, PC; Lee, BC; Mahagne, MH; Meseguer, E; Nighoghossian, N; Steg, PG; Vicaut, É | 1 |
Athyros, VG; Boutari, C; Karagiannis, A | 1 |
Kyselák, O; Soška, V | 1 |
Kamisako, T; Tanaka, Y | 1 |
Bastos, RT; Cruz, ECS; Derogis, PBMC; Dos Santos Ferreira, CE; Faccio, AT; Fonseca, FAH; Fontoura, SC; Izar, MC; Klassen, A; Lopes, AS; Neto, AMF; Picossi, CRC; Sussulini, A; Tavares, MFM | 1 |
Ahn, Y; Chae, IH; Cho, JM; Hong, SJ; Hong, TJ; Kang, TS; Kim, BJ; Kim, BS; Kim, JS; Kim, MH; Kim, SY; Kim, W; Lee, CW; Lee, SA; Rhee, MY; Shin, JH | 1 |
Jones, PJH; Mymin, D; Myrie, SB; Othman, RA; Roullet, JB; Steiner, RD | 1 |
Blanco-Vaca, F; Cedó, L; Escolà-Gil, JC | 1 |
Bergeron, J; Catapano, AL; Krempf, M; Lee, LV; Louie, MJ; Thompson, D | 1 |
Filipiak, KJ; Kapłon-Cieślicka, A; Kołtowski, Ł; Michalak, M | 1 |
Korman, M; Wisløff, T | 1 |
Ballantyne, CM; Baum, SJ; Howard, WB; Karayan, L; Knowles, JW; Myers, KD; Wilemon, KA | 1 |
Bartuli, A; Bertolini, S; Bruzzi, P; Buonuomo, PS; Calandra, S; Cortese, C; Iughetti, L; Papadia, F; Pisciotta, L; Rabacchi, C; Tummolo, A | 1 |
DeBarber, AE; Jones, PJH; Mymin, D; Myrie, SB; Othman, RA; Roullet, JB; Steiner, RD | 1 |
Bastida, JM; Benito, R; Díez-Campelo, M; Girós, M; González-Porras, JR; Hernández-Rivas, JM; Hernández-Sánchez, JM; Hortal, A; Janusz, K; Lozano, ML; Marcellini, S; Rivera, J | 1 |
Goździkiewicz, N; Kasprzak, M; Krintus, M; Kubica, J; Obońska, E; Obońska, K; Racki, K; Sikora, J | 1 |
Dent, R; Descamps, OS; Fraass, U; Gouni-Berthold, I; März, W | 1 |
Blom, DJ; Cannon, CP; Cariou, B; Chaudhari, U; Colhoun, HM; El Shahawy, M; Lecorps, G; McKenney, JM; Pordy, R | 1 |
Lloyd-Jones, DM | 1 |
Giugliano, RP; Sabatine, MS | 1 |
Cannon, CP; Khan, I; Klimchak, AC; Reynolds, MR; Sanchez, RJ; Sasiela, WJ | 1 |
Aoyama, K; Ichikawa, T; Kobayashi, K; Nakane, T; Sugita, K; Toda, T; Yagasaki, H | 1 |
Nozue, T | 1 |
Barthelmes, J; Sudano, I | 1 |
Wójcik, C | 1 |
Ballantyne, CM; Birtcher, KK; Daly, DD; DePalma, SM; Lloyd-Jones, DM; Minissian, MB; Morris, PB; Orringer, CE; Smith, SC | 1 |
Lin, XL; Liu, MH | 1 |
Frikke-Schmidt, R; Kobberø Lauridsen, B; Nordestgaard, BG; Stender, S; Tybjærg-Hansen, A | 1 |
Farnier, M | 2 |
Campos, AM; de Carvalho, LSF; Sposito, AC | 1 |
Battaggia, A; Donzelli, A; Scalisi, A | 1 |
Dembinski, T; Hatch, GM; Mymin, D; Salen, G; Triggs-Raine, B; Waggoner, DJ | 1 |
Awad, K; Banach, M; Katsiki, N; Mikhailidis, DP; Muntner, P | 1 |
Ahn, JC; Bae, JH; Cha, DH; Cho, SK; Chung, WS; Han, KR; Hong, SJ; Hyon, MS; Jeon, DW; Jeong, HS; Kim, HS; Kim, SY; Kim, W; Kwan, J; Lee, HC; Rha, SW; Rhee, MY; Shin, JH; Sung, KC; Won, KH; Yoo, BS; Yoo, KD | 1 |
Boklage, SH; Elassal, J; Ghannam, AF; Gupta, R; Karalis, DG; Mallya, UG | 1 |
Ahangari, N; Ghayour Mobarhan, M; Pasdar, A; Sahebkar, A | 1 |
Korman, MJ; Kristiansen, IS; Retterstøl, K; Wisløff, T | 1 |
Bae, JW; Han, SH; Hong, BK; Hong, SJ; Hwang, GS; Hyon, MS; Kim, JY; Kim, MK; Kim, SH; Kim, SW; Kim, W; Lee, SE; Park, CG; Park, JH; Rhee, MY; Shin, JH; Shin, SH; Son, JW; Sung, KC; Yoon, YE | 1 |
Firnhaber, JM | 1 |
Ballantyne, CM; Banach, M; Hanselman, JC; Leiter, LA; Lepor, NE; Mancini, GBJ; Zhao, X | 1 |
Alegre Del Rey, EJ; Gimeno Ballester, V; González-Outón, J; Matas Hoces, A; Olry de Labry Lima, A; Sierra Sánchez, JF | 1 |
Fukumoto, Y | 1 |
Bajnok, L | 1 |
Adam, S; Durrington, PN; Soran, H | 1 |
Ambegaonkar, B; Baxter, CA; Davies, G; Jansen, J; Lorenzi, M; Zoratti, MJ | 1 |
Ai, C; He, Q; Shi, J; Zhang, S | 1 |
Bessac, L; Cannon, CP; Davidson, MH; Eckel, RH; Ginsberg, HN; Lee, LV; Letierce, A; Pordy, R; Ray, KK; Vallejo-Vaz, AJ | 1 |
Bailey, AL; Beam, C; Birtcher, KK; Blumenthal, RS; Braun, LT; de Ferranti, S; Faiella-Tommasino, J; Forman, DE; Goldberg, R; Grundy, SM; Heidenreich, PA; Hlatky, MA; Jones, DW; Lloyd-Jones, D; Lopez-Pajares, N; Ndumele, CE; Orringer, CE; Peralta, CA; Saseen, JJ; Smith, SC; Sperling, L; Stone, NJ; Virani, SS; Yeboah, J | 2 |
Barrett, HPR; Chan, DC; Ma, L; Ooi, EMM; Parhofer, KG; Waldmann, E; Watts, GF | 1 |
Crump, B | 1 |
He, F; Li, T; Li, Z; Liu, X; Su, J; Wu, W; Xu, R; Yan, Y; Zhao, M | 1 |
Al-Rasadi, K; Atkin, SL; Banach, M; Pirro, M; Sahebkar, A; Simental-Mendía, LE; Sirtori, C; Watts, GF | 1 |
Amornlerdpison, D; Duangjai, A; Muanprasat, C; Ontawong, A; Pasachan, T; Pongchaidecha, A; Srimaroeng, C | 1 |
Fazio, S; Weitz, JI | 1 |
Ding, S; Du, S; Luo, P; Shen, S; Wang, G; Wang, L; Zhao, Z | 1 |
Li, Y; Pan, R; Zhou, H | 1 |
Blé-Castillo, JL; Díaz-Zagoya, JC; Juárez-Rojop, IE; Marín-Medina, A; Ruíz-Hidalgo, G; Zamora, RM; Zetina-Esquivel, AM | 1 |
Chan, P; Liu, Z; Ma, YB; Tomlinson, B; Zhang, Y | 1 |
Bang, LE; Gislason, GH; Høfsten, DE; Jensen, JS; Køber, LV; Pallisgaard, J; Ripa, MS; Schjerning, AM; Theilade, JE; Weeke, PE | 1 |
Al Rifai, M; Birnbaum, Y; Jia, X; Smith, SC; Virani, SS | 1 |
Blumenthal, RS; Chuzi, S; Grundy, SM; Lloyd-Jones, DM; Pfenniger, A; Smith, SC; Stone, NJ; Virani, SS | 1 |
Damonte, J; Halsband, A; Masson, W; Pizarro, R; Rossi, E; Siniawski, D | 1 |
Hovingh, GK; Ray, KK; Reeskamp, LF | 1 |
Khan, SU; Michos, ED | 1 |
Feingold, KR | 1 |
Ballantyne, CM; Bays, HE; Catapano, AL; Goldberg, AC; Laufs, U; Leiter, LA; MacDougall, D; Ray, KK; Stroes, ES; Zhao, X | 1 |
Behm, MO; Fujimoto, K; Furihata, K; Matsumoto, Y; Nishida, C; Shirakawa, M; Wrishko, RE | 1 |
Brath, H; Kästenbauer, T; Toplak, H; Wascher, TC | 1 |
Boden, WE; Hartigan, PM; Maron, DJ; Neff, DR; Weintraub, WS | 1 |
Chen, MH; Ibrahim, JG; Kim, S; Lin, J; Shah, AK | 1 |
Brudi, P; Farnier, M; Guyton, JR; Jensen, E; Johnson-Levonas, AO; Polis, AB | 1 |
Fukushima, Y; Higuchi, K; Hirayama, S; Inoue, M; Kamimura, Y; Miida, T; Nakagawa, S; Nishioka, E; Ohmura, H; Seino, U; Soda, S; Ueno, T; Yamato, S | 1 |
Adler, C; Bögl, K; Drexel, H; Eber, B; Fauer, C; Föchterle, J; Föger, B; Gansch, K; Grafinger, P; Lautsch, D; Lechleitner, M; Ludvik, B; Maurer, G; Mörz, R; Paulweber, B; Pfeiffer, KP; Pichler, M; Prager, R; Stark, G; Toplak, H; Traindl, O; Weitgasser, R | 1 |
Amber, V; Hall, GC; Jameson, K; O'Regan, C | 1 |
Arao, T; Hajime, M; Inokuchi, N; Kurozumi, A; Matsuoka, H; Mori, H; Narisawa, M; Okada, Y; Tanaka, K; Tanaka, Y; Torimoto, K; Yamamoto, S | 1 |
Averna, M; Bays, HE; Brudi, P; De Pellegrin, A; Farnier, M; Giezek, H; Lee, R; Lowe, RS; Majul, C; Muller-Wieland, D; Triscari, J | 1 |
Hirano, T; Iijima, R; Inazawa, T; Kawamura, M; Kitazawa, T; Kohro, T; Mori, Y; Sakamoto, K; Shiba, T; Tagami, M; Tanaka, A; Yamazaki, T | 1 |
Elisaf, MS; Liberopoulos, EN; Milionis, HJ; Moutzouri, E; Tellis, CC; Tselepis, AD | 1 |
Sano, M | 1 |
Jones, PJ; Myrie, SB; Othman, RA | 1 |
Braamskamp, MJ; Hutten, BA; Kastelein, JJ; Wiegman, A | 1 |
Bandyopadhyay, S; Katare, OP; Singh, B | 2 |
Ballantyne, CM; Cain, VA; Hoogeveen, RC; Karlson, BW; Palmer, MK; Raya, JL | 1 |
Ben-Yehuda, O; Constance, C; Hanson, ME; Lin, J; Lowe, RS; Tershakovec, AM; Wenger, NK; Zieve, F | 1 |
Baumgartner, I; März, W; Silbernagel, G; Wanner, C | 1 |
Alsabbagh, WM; Blackburn, DF; Dagenais, J; Lix, LM; Lu, X; Shevchuk, Y; Teare, GF; Yan, L | 1 |
Cho, L; Colquhoun, D; Dent, R; Rocco, M; Rosenson, RS; Scott, R; Stroes, E; Sullivan, D; Wasserman, SM; Xue, A | 2 |
Fialkow, J; Legg, JC; Nedergaard, BS; Nelson, P; Neutel, JM; Ramstad, D; Robinson, JG; Rogers, WJ; Scott, R; Somaratne, R; Wasserman, SM; Weiss, R | 2 |
Chelladurai, Y; Gudzune, KA; Monroe, AK; Ranasinghe, PD; Robinson, KA; Sharma, R | 1 |
Li, JJ; Li, S; Liu, J; Sun, J; Xu, RX; Zhang, Y | 1 |
Gürsel, T; Kaya, Z; Niu, DM; Tekin, A; Yorulmaz, A | 1 |
Chang, WT; Huang, SK; Liau, I; Yang, YC | 1 |
Mitka, M | 2 |
Berthold, HK; Gouni-Berthold, I; Krone, W; Montalto, G; Rizzo, M; Spenrath, N | 1 |
Pan, XD; Sun, LY; Wang, LY; Wu, WF; Yang, SW | 1 |
Du, S; Han, YG; Li, L; Luo, P; Wang, GG; Wang, LX; Wu, SL; Zhu, HH | 1 |
Jackevicius, CA; Ko, DT; Krumholz, HM; Lu, L; Ross, JS; Tu, JV | 1 |
Huang, W; Qian, H; Sun, L | 1 |
Machnik, G; Okopień, B; Suchy, D; Łabuzek, K | 1 |
Blanco-Vaca, F; Cedó, L; Escolà-Gil, JC; Julve, J; Martín-Campos, JM; Quesada, H | 1 |
Krysiak, R; Okopień, B; Żmuda, W | 4 |
Coticchia, CM; Curatolo, AS; Moses, MA; Pelton, K; Schaffner, CP; Solomon, KR; Zurakowski, D | 1 |
Reiner, Z | 1 |
Baccara-Dinet, MT; Colhoun, HM; Ginsberg, HN; Kastelein, JJ; Merlet, L; Pordy, R; Robinson, JG; Roth, EM; Taskinen, MR | 1 |
Frazee, SG; Garavaglia, SB; Jackevicius, CA; Krumholz, HM; Levin, R; Novshadian, H; Ross, JS; Stettin, G | 1 |
Levesque, MC; Liang, KP; Mock, GD; Modi, SR; Ruiz, XD | 1 |
Bays, H; Li, Y; Louder, A; Mallick, R; Schwab, P | 1 |
Krysiak, R; Marek, B; Okopień, B; Zmuda, W | 3 |
Krysiak, R; Okopien, B | 2 |
Gaciong, Z; Lewandowski, J; Puchalska, L; Siński, M; Symonides, B | 1 |
Bays, HE; Chen, E; McPeters, G; Polis, AB; Tomassini, JE; Triscari, J | 1 |
Jones, PJ; Merkens, LS; Mymin, D; Myrie, SB; Othman, RA; Roullet, JB; Steiner, RD | 1 |
Cui, CJ; Li, JJ; Li, S | 1 |
Lee, TC; McDonald, EG; Saleh, RR | 1 |
Ambegaonkar, BM; Polis, AB; Tershakovec, AM; Tipping, D; Tomassini, JE | 1 |
Adachi, H; Bekki, H; Honma, T; Nakano, H; Nakata, M; Nohara, M; Yamamoto, K; Yoshiyama, H | 1 |
Caamaño, J; Lanas, F; Saavedra, N; Salazar, LA; Zambrano, T | 1 |
Ferenci, T; Simonyi, G | 1 |
McKenney, JM; Roth, EM | 1 |
Einecke, D | 2 |
Parhofer, K | 1 |
Ambegaonkar, BM; Cao, X; Ejzykowicz, F; Mavros, P; Ramey, DR; Sajjan, S; Tunceli, K | 1 |
Angeli, V; Khoo, LH; Soh, SY; Thiam, CH | 1 |
Huang, W; Luo, L; Ren, F; Tang, L; Yuan, X; Zheng, Y; Zhu, H | 1 |
Blom, D; Cannon, CP; Cariou, B; Chaudhari, U; Colhoun, HM; Lorenzato, C; McKenney, JM; Pordy, R | 1 |
Civeira, F; Masana, L; Pedro-Botet, J | 1 |
Emery, M; Langslet, G; Wasserman, SM | 1 |
Caceres, M; Coll, M; Cuffie, C; Gagné, C; Jacobson, MS; Kastelein, JJ; Kusters, DM; Kwiterovich, PO; Lee, R; Lowe, RS; Massaad, R; McCrindle, BW; Musliner, TA; Triscari, J | 1 |
Frikke-Schmidt, R; Lauridsen, BK; Nordestgaard, BG; Stender, S; Tybjærg-Hansen, A | 1 |
Doi, M; Ito, H; Miyoshi, T; Nakamura, K | 1 |
Alves, C; Cerda, A; Dorea, EL; Fajardo, CM; Genvigir, FD; Gusukuma, MC; Hirata, MH; Hirata, RD; Pinto, GA; Rodrigues, AC | 1 |
Brudi, P; Descamps, O; Hanson, ME; Lin, J; Polis, AB; Shah, A; Tershakovec, AM; Tomassini, JE | 1 |
Deckers, JW; Simoons, ML | 2 |
Azuma, K; Hanson, ME; Kakikawa, T; Oshima, N; Saito, I; Tershakovec, AM | 1 |
Tsimikas, S; Witztum, JL; Yeang, C | 1 |
Brudi, P; Farnier, M; Giezek, H; Krempf, M; Lee, R; Ramey, DR; Simpson, RJ; Tomassini, JE | 1 |
Signy, J; Signy, M | 1 |
Poli, A | 1 |
Balakrishnan, A; Cassis, LA; Daugherty, A; Howatt, DA; Liu, J; Lu, H; Moorleghen, JJ; Sorci-Thomas, M | 1 |
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Hansen, EH; Wallach-Kildemoes, H | 1 |
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Bays, H; Bird, S; Conard, S; Hanson, ME; Leiter, LA; Rubino, J; Tershakovec, AM; Tomassini, JE | 1 |
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Ballantyne, CM; Bird, S; Lin, J; Pearson, TA; Rosenberg, E; Shah, A; Tershakovec, AM; Veltri, E | 1 |
Hanson, M; Hoffman, R; Strony, J; Veltri, E | 1 |
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Allgar, V; Chipperfield, R; Gaunt, R; Harvey, P; McCormack, T; Robinson, P | 1 |
Drakopoulou, M; Skoumas, I; Stefanadis, C; Toutouzas, K | 1 |
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Bays, HE; Bird, SR; Conard, SE; Leiter, LA; Lowe, RS; Tershakovec, AM | 1 |
Montgomery, BD | 1 |
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Bays, H; Conard, S; Hanson, ME; Leiter, LA; Lin, J; Shah, A; Tershakovec, AM | 1 |
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Betteridge, DJ; Brudi, P; Farnier, M; Guyton, JR; Johnson-Levonas, AO; Leiter, LA; Lin, J; Shah, A | 1 |
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Alizadeh, J; Ballantyne, CM; Lipka, LJ; Sager, PT; Strony, J; Suresh, R; Veltri, EP | 1 |
Boutros, T; Cutler, DL; Kosoglou, T; Maxwell, SE; Statkevich, P; Suresh, R; Tiessen, R; Yang, B; Zhu, Y | 1 |
Cutler, DL; Fruchart, JC; Guillaume, M; Kosoglou, T; Maxwell, SE; Pember, LJ; Reyderman, L; Statkevich, P; Veltri, EP | 1 |
Ballantyne, CM; Davidson, MH; Kerzner, B; Lipka, L; Melani, L; Sager, PT; Strony, J; Suresh, R; Veltri, E | 1 |
Ballantyne, CM; Chiou, P; Guyton, JR; Jones, PH; Stein, JL; Xydakis, AM | 1 |
Gumbiner, B; Lee, M; Maccubbin, D; Masana, L; Shah, A; Simons, L; Tonkon, M | 1 |
Kroemer, HK; Meyer Zu Schwabedissen, H | 1 |
Lipka, L; Maccubbin, D; Mata, P; Melani, L; Ponsonnet, D; Sager, P; Stein, E; Stender, S; Suresh, R; Veltri, E | 1 |
Diz-Lois, F | 1 |
Patel, SB | 1 |
Kvapil, M | 1 |
Murdoch, D; Scott, LJ | 1 |
Batta, AK; Bollineni, JS; Salen, G; Shefer, S; Xu, G | 1 |
Charlotte, N; Sani, M | 1 |
Lipka, L; Sager, P; Strony, J; Suresh, R; Veltri, E; Yang, B | 1 |
Bays, HE; Donahue, SR; Fraser, N; Johnson-Levonas, AO; Ose, L; Quinto, K; Reyes, R; Sapre, A; Tribble, DL | 1 |
Bennett, S; Lipka, L; Melani, L; Sager, P; Suresh, R; Veltri, E | 1 |
Alemao, E; Cook, JR; Drummond, M; Yin, D | 1 |
Alemao, E; Badia, X; Cook, JR; Davies, G; Krobot, KJ; Lipka, L; Veltri, E; Yin, D | 1 |
Sawicki, PT; Weizel, A | 1 |
Haghfelt, T | 1 |
Capece, R; Lipka, L; Mitchel, Y; Sager, PT; Strony, J; Suresh, R; Veltri, E; Yang, B | 1 |
Cho, M; Gagné, C; Gumbiner, B; Johnson-Levonas, AO; Masana, L; Mata, P; Meehan, A; Sirah, W; Troxell, JK | 1 |
Geiss, HC; Hund-Wissner, E; Otto, C; Parhofer, KG | 1 |
Keough-Ryan, T; Kiberd, BA; Kiberd, M; Lawen, J; Puthenparumpil, JJ | 1 |
Taéron, C | 1 |
Abate, N; Ballantyne, CM; King, TR; Palmisano, J; Yuan, Z | 1 |
Hurley, DL; Isley, WL | 1 |
Battisti, WP; Brady, WE; Denke, MA; McBride, PE; Palmisano, J; Pearson, TA | 1 |
Alings, AM; Allen, C; Banai, S; Brohet, C; Davies, MJ; Massaad, R | 1 |
Adgey, J; Allen, C; Bedarida, GV; Cruz-Fernández, JM; Johnson-Levonas, AO; Massaad, R | 1 |
Chandrasekar, D; Diwan, PV; Kashyap, YV; Sistla, R; Tata, VS | 1 |
Chacón, P; Fonollosa, V; Lima, J | 1 |
Al-Saady, N; Daskalopoulou, SS; Griffiths, H; Hamilton, G; Mikhailidis, DP; Monkman, D; Patel, V; Pittard, J; Schachter, M; Wierzbicki, AS | 1 |
Allen, C; Davies, MJ; Farnier, M; Massaad, R; Volpe, M | 1 |
Lütjohann, D; Sudhop, T; von Bergmann, K | 1 |
Brady, WE; Catapano, A; King, TR; Palmisano, J | 1 |
Cole, P; Rabasseda, X | 1 |
Cutler, DL; Kosoglou, T; Maxwell, S; Reyderman, L; Statkevich, P | 1 |
Ban, MR; Guy, J; Hegele, RA; Wang, J | 1 |
van Heyningen, C | 1 |
Sármán, B | 1 |
Chandalia, M; Jialal, I | 1 |
Allen, C; Amabile, N; Barrios, V; Chen, JW; Johnson-Levonas, AO; Massaad, R; Paganelli, F; Vandormael, K | 1 |
Araújo, RG; Casella Filho, A; Chagas, AC | 1 |
Heemann, U; Kohnle, M; Kribben, A; Philipp, T; Pietruck, F; Witzke, O | 1 |
Fisher, EA; Schwartzbard, A; Yatskar, L | 1 |
Cohn, JS; Couture, P; Hogue, JC; Lamarche, B; Tremblay, AJ | 1 |
Chuang, P; Langone, AJ | 1 |
Daskalopoulou, SS; Mikhailidis, DP | 1 |
Geiss, HC; Otto, C; Parhofer, KG | 1 |
Holland, RC; Lopez, D; Ness, GC | 1 |
Benecke, H; Bestehorn, K; Karmann, B; Renner, H; Völler, H; Wegscheider, K | 1 |
Davies, MJ; Maccubbin, D; Mitchel, Y; Ose, L; Rotonda, J; Shah, A; Tribble, D; Veltri, E | 1 |
Kerzner, B; Rodney, RA; Strony, J; Sugimoto, D; Suresh, R; Veltri, E; Wagman, B; Yang, B; Zieve, F | 1 |
Becx, MC; Kuypers, KC; Seldenrijk, CA; Stolk, MF | 1 |
Arteaga Ll, A; Maiz G, A; Rigotti R, A | 1 |
Capps, N | 1 |
Davidson, M; Feldman, T; Maccubbin, D; Meehan, A; Mitchel, Y; Shah, A; Tribble, D; Veltri, E; Zakson, M | 1 |
Hughes, EA; Patel, JV | 1 |
Alemao, E; Attard, C; Bourgault, C; Cook, J; Huse, D; Kohli, M; Lam, A; Marentette, M; Yin, D | 1 |
Davidson, MH; Robinson, JG | 1 |
Czuriga, I; Edes, I | 1 |
Battisti, WP; Brady, WE; Denke, MA; Gazzara, RA; McBride, PE; Palmisano, J; Pearson, TA | 1 |
Bissonnette, S; Boukas, S; Habib, R; Sampalis, F; Sampalis, JS | 1 |
Burnett, JR; Huff, MW | 1 |
Abby, S; Bays, H; Jones, M; Lai, YL; Rhyne, J | 1 |
Gazi, IF; Mikhailidis, DP | 1 |
Anderson, S; Fish, B; Knopp, RH; Nguyen, H; Nguyen, T; Retzlaff, BM; Tsunehara, C | 1 |
Edwards, P; Goldberg, RB; Guyton, JR; Mazzone, T; Polis, A; Tershakovec, AM; Tomassini, JE; Weinstock, RS | 1 |
Bitzur, R; Cohen, H; Harats, D | 1 |
Pasierski, T; Pikto-Pietkiewicz, W | 1 |
Katz, U; Shoenfeld, Y; Szyper-Kravitz, M; Zimlichman, E | 1 |
Ballantyne, CM; Duffield, E; Eber, B; Moccetti, T; Sosef, F; Vogt, A; Weiss, R | 1 |
Ambrose, MS; Cote, H; DeNofrio, D; Duffy, GA; Patel, AR | 1 |
Shechter, M | 1 |
Fischer, S; Jaster, M; Martus, P; Morguet, AJ; Piorkowski, M; Rauch, U; Schultheiss, HP; Stellbaum, C | 1 |
Abinader, EG | 1 |
Márk, L; Paragh, G | 1 |
Alonso K, R; Arteaga Ll, A; Castillo, S; Cuevas M, A; González, F; Mata L, P; Rigotti R, A | 1 |
Blagden, MD; Chipperfield, R | 1 |
Blaimont, M; Chenot, F; de Meester, A; Descamps, OS; Marcovitch, O; Montant, PF | 1 |
Johnson, RR; Sweeney, ME | 1 |
Dani, G; Fazekas, O; Katona, A; Kovacs, H; Mark, L; Szüle, O | 1 |
Angelin, B; Gälman, C; Matasconi, M; Parini, P; Persson, L; Rudling, M | 1 |
Davis, HR; Veltri, EP | 1 |
Devaraj, S; Jialal, I | 1 |
Johnson-Levonas, A; Lin, J; Musliner, T; Ose, L; Reyes, R; Shah, A; Tribble, D | 1 |
Ballantyne, CM; Catapano, AL; Davies, GM; Mikhailidis, DP; Sibbring, GC | 1 |
Bissonnette, S; Boukas, S; Habib, R; Sampalis, JS | 1 |
Daskalopoulou, SS; Gazi, IF; Mikhailidis, DP; Nair, DR | 1 |
Carlson, HE; John-Kalarickal, J; Pearlman, G | 1 |
Spener, F | 1 |
Heemann, U; Kohnle, M; Kribben, A; Nürnberger, J; Philipp, T; Türk, TR; Voropaeva, E; Witzke, O | 1 |
Berthold, J; Krone, W | 1 |
Catapano, AL | 1 |
Assmann, G; Gutkin, SW; Kannenberg, F; Musliner, TA; Ramey, DR; Veltri, EP | 1 |
Acton, S; Braun, A; Broschat, KO; Krieger, M; Krul, ES; Napawan, N; Stagliano, N; Yesilaltay, A | 1 |
Berthold, HK; Gouni-Berthold, I; Gylling, H; Krone, W; Laaksonen, R; Lehtimäki, T | 1 |
Johnson-Levonas, AO; Musliner, T; Ose, L; Reyes, R; Sapre, A; Tribble, DL | 1 |
Elisaf, MS; Florentin, M; Liberopoulos, EN | 1 |
Hussein, O; Itzkovich, Y; Minasian, L; Shestatski, K; Solomon, L; Zidan, J | 1 |
Allen, C; Brudi, P; Henry, P; Johnson-Levonas, AO; Lim, ST; Lis, K; Massaad, R; Pomykaj, T; Reckless, JP; Vandormael, K | 1 |
Athyros, VG; Kakafika, AI; Karagiannis, A; Koumaras, H; Mikhailidis, DP; Tziomalos, K | 1 |
Viljoen, A; Wierzbicki, AS | 1 |
Alvarez-Sala, LA; Cachofeiro, V; Gambus, G; Lahera, V; Masana, L; Moreno, MA; Pinilla, B; Pintó, X; Plana, N; Suarez, C; Trias, F | 1 |
Antoniades, C; Chrysohoou, C; Giotsas, N; Masoura, C; Metalinos, G; Papadimitriou, L; Pitsavos, C; Skoumas, I; Stefanadis, C; Tousoulis, D; Toutouza, M | 1 |
Thompson, CA | 1 |
Jackevicius, CA; Ko, DT; Krumholz, HM; Ross, JS; Tu, JV | 1 |
Angelin, B; Bonde, Y; Gälman, C; Matasconi, M; Rudling, M | 1 |
Lindsley, CW | 1 |
Bays, HE; Neff, D; Tershakovec, AM; Tomassini, JE | 1 |
Barnett, D; Charles, Z; Pugh, E | 1 |
Armitage, J | 1 |
Barho, C; Bode, C; Darius, H; Hildemann, S; Karmann, B; Pittrow, D | 1 |
Gaughan, JP; Klibanov, OM; Tedaldi, EM; van den Berg-Wolf, M | 1 |
Bauersachs, J; Ertl, G; Hu, K; Huang, PL; Kuhlencordt, PJ; Padmapriya, P; Rützel, S; Schäfer, A; Schödel, J | 1 |
Ara, R; Chilcott, J; Duenas, A; Paisley, S; Pandor, A; Tumur, I; Wilkinson, A; Williams, R | 1 |
Bheemreddy, S; Foody, JM; Kashani, A; Mann, DL; Sallam, T; Wang, Y | 1 |
Bloedon, LT; McKenney, J; Rader, DJ; Samaha, FF; Sasiela, WJ | 1 |
Compton, DS; Davis, HR; van Heek, M | 1 |
Brown, WV | 2 |
Austin, TM; Cook, JA; Davis, HR; Farley, C; Tetzloff, GG; van Heek, M | 1 |
Batra, V; Ezzet, F; Kosoglou, T; Lipka, L; Mellars, L; Patrick, J; Statkevich, P; Veltri, E; Wexler, D | 1 |
Bays, HE; Cuffie-Jackson, C; Drehobl, MA; Dujovne, CA; Knopp, RH; Lebeaut, AP; Lipka, LJ; Mellars, LE; Moore, PB; Rosenblatt, S; Toth, PD; Veltri, EP; Yang, B | 1 |
Meng, CQ | 1 |
Alton, KB; Burrier, RE; Davis, HR; Pula, KK; Watkins, RW | 1 |
Aumiller, J | 1 |
Miettinen, TA | 1 |
Stein, EA | 1 |
Leitersdorf, E | 1 |
149 review(s) available for ezetimibe and Elevated Cholesterol
Article | Year |
---|---|
Niemann-Pick C1-Like 1 inhibitors for reducing cholesterol absorption.
Topics: Anticholesteremic Agents; Biological Transport; Cholesterol; Ezetimibe; Humans; Hypercholesterolemia; Intestinal Absorption; Membrane Transport Proteins | 2022 |
The Effects of Statin Dose, Lipophilicity, and Combination of Statins plus Ezetimibe on Circulating Oxidized Low-Density Lipoprotein Levels: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Topics: Atherosclerosis; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Humans; Hydrophobic and Hydrophilic Interactions; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoproteins, LDL; Oxygen; Randomized Controlled Trials as Topic; Regression Analysis; Risk Factors; Treatment Outcome | 2021 |
High-Intensity Statins Benefit High-Risk Patients: Why and How to Do Better.
Topics: Anticholesteremic Agents; Cholesterol, LDL; Coronary Artery Disease; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Primary Prevention; Secondary Prevention | 2021 |
New insights into the role of bempedoic acid and ezetimibe in the treatment of hypercholesterolemia.
Topics: Anticholesteremic Agents; Cholesterol, LDL; Dicarboxylic Acids; Ezetimibe; Fatty Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipidemias; Randomized Controlled Trials as Topic; Treatment Outcome | 2022 |
Comparative efficacy of non-statin lipid-lowering therapies in patients with hypercholesterolemia at increased cardiovascular risk: a network meta-analysis.
Topics: Anticholesteremic Agents; Bayes Theorem; Cardiovascular Diseases; Cholesterol; Cholesterol, LDL; Ezetimibe; Heart Disease Risk Factors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipidemias; Network Meta-Analysis; Risk Factors; Treatment Outcome | 2022 |
[From statin revolution to gene silencing therapy: 50 years of evolution in the treatment of hypercholesterolemia].
Topics: Anticholesteremic Agents; Atherosclerosis; Cardiovascular Diseases; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Gene Silencing; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipidemias; Proprotein Convertase 9 | 2022 |
Association Between Baseline, Achieved, and Reduction of CRP and Cardiovascular Outcomes After LDL Cholesterol Lowering with Statins or Ezetimibe: A Systematic Review and Meta-Analysis.
Topics: Anticholesteremic Agents; C-Reactive Protein; Cardiovascular Diseases; Cholesterol, LDL; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Myocardial Infarction; Myocardial Revascularization; Stroke; Treatment Outcome | 2019 |
LDL-cholesterol: The lower the better.
Topics: Anion Exchange Resins; Antibodies, Monoclonal; Anticholesteremic Agents; Cardiovascular Diseases; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; PCSK9 Inhibitors; Risk | 2019 |
Efficacy of combination therapy with ezetimibe and statins versus a double dose of statin monotherapy in participants with hypercholesterolemia: a meta-analysis of literature.
Topics: Aged; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Drug Combinations; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged | 2020 |
[Approach to Patients with Statin Intolerance: Evidence-Based Review].
Topics: Cardiovascular Diseases; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Meta-Analysis as Topic; Practice Guidelines as Topic; Systematic Reviews as Topic | 2020 |
An overview of rosuvastatin/ezetimibe association for the treatment of hypercholesterolemia and mixed dyslipidemia.
Topics: Anticholesteremic Agents; Cholesterol; Cholesterol, LDL; Drug Synergism; Drug Therapy, Combination; Dyslipidemias; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Rosuvastatin Calcium; Treatment Outcome; Triglycerides | 2020 |
PCSK9 Inhibitors: From Nature's Lessons to Clinical Utility.
Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; PCSK9 Inhibitors | 2020 |
A Review of the Efficacy and Tolerability of Bempedoic Acid in the Treatment of Hypercholesterolemia.
Topics: Anticholesteremic Agents; Cholesterol, LDL; Dicarboxylic Acids; Drug Combinations; Dyslipidemias; Ezetimibe; Fatty Acids; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Randomized Controlled Trials as Topic; Receptors, LDL | 2020 |
Low-density lipoprotein cholesterol lowering treatment: the current approach.
Topics: Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Atherosclerosis; Benzimidazoles; Bile Acids and Salts; Carrier Proteins; Cholesterol, LDL; Dicarboxylic Acids; Europe; Ezetimibe; Fatty Acids; Gene Expression; Guidelines as Topic; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; PCSK9 Inhibitors; Proprotein Convertase 9; RNA, Small Interfering | 2020 |
Role of non-statin lipid-lowering therapy in coronary atherosclerosis regression: a meta-analysis and meta-regression.
Topics: Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Cholesterol, LDL; Coronary Artery Disease; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; PCSK9 Inhibitors; Treatment Outcome; Ultrasonography | 2020 |
Clinical Pharmacology of Statins: an Update.
Topics: Adolescent; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Atherosclerosis; Child; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; PCSK9 Inhibitors; Primary Prevention; RNA, Small Interfering; Treatment Outcome | 2020 |
Rosuvastatin/Ezetimibe: A Review in Hypercholesterolemia.
Topics: Anticholesteremic Agents; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Rosuvastatin Calcium | 2020 |
Efficacy and safety of add on therapies in patients with hypercholesterolemia undergoing statin therapy.
Topics: Antibodies, Monoclonal, Humanized; Cholesterol, LDL; Clinical Trials as Topic; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; PCSK9 Inhibitors; Treatment Outcome | 2020 |
Meta-Analysis of Inclisiran for the Treatment of Hypercholesterolemia.
Topics: Aged; Alanine Transaminase; Alkaline Phosphatase; Anticholesteremic Agents; Apolipoproteins B; Aspartate Aminotransferases; Bilirubin; Cardiovascular Diseases; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Creatine Kinase; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Injection Site Reaction; Male; Middle Aged; Myocardial Infarction; Randomized Controlled Trials as Topic; RNA, Small Interfering; Stroke | 2020 |
Bempedoic Acid and Ezetimibe for the Treatment of Hypercholesterolemia: A Systematic Review and Meta-Analysis of Randomized Phase II/III trials.
Topics: Anticholesteremic Agents; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dicarboxylic Acids; Drug Combinations; Ezetimibe; Fatty Acids; Humans; Hypercholesterolemia; Randomized Controlled Trials as Topic; Triglycerides | 2021 |
Statin intolerance: new data and further options for treatment.
Topics: Anticholesteremic Agents; Cardiovascular Diseases; Cholesterol, LDL; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Proprotein Convertase 9 | 2021 |
Clinical development of bempedoic acid: phase 2 and phase 3 clinical trials.
Topics: Cholesterol, LDL; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Dicarboxylic Acids; Drug Development; Drug Therapy, Combination; Ezetimibe; Fatty Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Inflammation | 2021 |
Fixed-dose combination of rosuvastatin and ezetimibe: treating hypercholesteremia according to cardiovascular risk.
Topics: Anticholesteremic Agents; Cholesterol, LDL; Drug Combinations; Ezetimibe; Heart Disease Risk Factors; Humans; Hypercholesterolemia; Medication Adherence; Rosuvastatin Calcium | 2021 |
Two novel variants of the ABCG5 gene cause xanthelasmas and macrothrombocytopenia: a brief review of hematologic abnormalities of sitosterolemia.
Topics: Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 5; DNA Mutational Analysis; Ezetimibe; Female; Genetic Predisposition to Disease; High-Throughput Nucleotide Sequencing; Humans; Hypercholesterolemia; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Lipoproteins; Middle Aged; Mutation; Phenotype; Phytosterols; Sitosterols; Spain; Thrombocytopenia; Xanthomatosis | 2017 |
Anti-PCSK9 antibodies for hypercholesterolaemia: Overview of clinical data and implications for primary care.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Cardiovascular Diseases; Cholesterol, LDL; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; PCSK9 Inhibitors; Primary Health Care; Proprotein Convertase 9 | 2017 |
Lipid Lowering Therapy and Circulating PCSK9 Concentration.
Topics: Antibodies, Monoclonal; Biomarkers; Cholesterol, LDL; Ezetimibe; Fibric Acids; Gene Silencing; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Lipid Metabolism; Niacin; PCSK9 Inhibitors; Proprotein Convertase 9 | 2017 |
Topics: Cholesterol, LDL; Ezetimibe; Fibric Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; PCSK9 Inhibitors; Secondary Prevention | 2017 |
Incorporation of PCSK9 inhibitors into prevention of atherosclerotic cardiovascular disease.
Topics: Anticholesteremic Agents; Atherosclerosis; Cardiovascular Diseases; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; PCSK9 Inhibitors; Practice Guidelines as Topic; Proprotein Convertase 9 | 2017 |
Alirocumab for the treatment of hyperlipidemia in high-risk patients: an updated review.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Cholesterol, LDL; Ezetimibe; Humans; Hypercholesterolemia; PCSK9 Inhibitors; Treatment Outcome | 2017 |
Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitors and Incident Type 2 Diabetes: A Systematic Review and Meta-analysis With Over 96,000 Patient-Years.
Topics: Blood Glucose; Cholesterol, LDL; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; PCSK9 Inhibitors; Randomized Controlled Trials as Topic | 2018 |
The systematic review of randomized controlled trials of PCSK9 antibodies challenges their "efficacy breakthrough" and the "lower, the better" theory.
Topics: Anticholesteremic Agents; Cardiovascular Diseases; Cholesterol, LDL; Ezetimibe; Humans; Hypercholesterolemia; Proprotein Convertase 9; Randomized Controlled Trials as Topic; Treatment Outcome | 2018 |
Effect of Ezetimibe Monotherapy on Plasma Lipoprotein(a) Concentrations in Patients with Primary Hypercholesterolemia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Topics: Anticholesteremic Agents; Cholesterol, LDL; Databases, Pharmaceutical; Dose-Response Relationship, Drug; Ezetimibe; Hypercholesterolemia; Lipoprotein(a); Randomized Controlled Trials as Topic; Treatment Outcome; Triglycerides | 2018 |
Molecular aspects of hypercholesterolemia treatment: current perspectives and hopes.
Topics: Angiopoietin-Like Protein 3; Angiopoietin-like Proteins; Anticholesteremic Agents; Atherosclerosis; Bile Acids and Salts; Cholesterol, LDL; Disease Progression; Ezetimibe; Genetic Therapy; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestinal Absorption; Intestinal Mucosa; MicroRNAs; Mutation; PCSK9 Inhibitors; Proprotein Convertase 9; Receptors, LDL; RNA, Small Interfering; Sequestering Agents | 2018 |
Are PCSK9 Inhibitors Cost Effective?
Topics: Anticholesteremic Agents; Cost-Benefit Analysis; Drug Therapy, Combination; Enzyme Inhibitors; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; PCSK9 Inhibitors; Quality-Adjusted Life Years | 2018 |
Optimising treatment of hyperlipidaemia: Quantitative evaluation of UK, USA and European guidelines taking account of both LDL cholesterol levels and cardiovascular disease risk.
Topics: Anticholesteremic Agents; Atorvastatin; Cardiology; Cardiovascular Diseases; Cholesterol, LDL; Europe; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipidemias; Oxazolidinones; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Risk Factors; United Kingdom; United States | 2018 |
Ezetimibe in high-risk, previously treated statin patients: a systematic review and network meta-analysis of lipid efficacy.
Topics: Anticholesteremic Agents; Bayes Theorem; Biomarkers; Cardiovascular Diseases; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Global Health; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Incidence; Risk Factors | 2019 |
Comparing the combination therapy of ezetimibe and atorvastatin with atorvastatin monotherapy for regulating blood lipids: a systematic review and meta-analyse.
Topics: Atorvastatin; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Triglycerides | 2018 |
Impact of ezetimibe on plasma lipoprotein(a) concentrations as monotherapy or in combination with statins: a systematic review and meta-analysis of randomized controlled trials.
Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoprotein(a); Male; Middle Aged; Placebos; Plasma; Randomized Controlled Trials as Topic; Treatment Outcome; Young Adult | 2018 |
Comparative efficacy and safety of lipid-lowering agents in patients with hypercholesterolemia: A frequentist network meta-analysis.
Topics: Adult; Aged; Comparative Effectiveness Research; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Lipids; Male; Middle Aged; Network Meta-Analysis; PCSK9 Inhibitors; Treatment Outcome | 2019 |
Efficacy and safety of different doses of alirocumab in reducing low-density lipoprotein cholesterol levels: a network meta-analysis.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Cholesterol, LDL; Dose-Response Relationship, Drug; Ezetimibe; Humans; Hypercholesterolemia; Network Meta-Analysis; PCSK9 Inhibitors | 2019 |
Evaluating the efficacy and safety of atorvastatin + ezetimibe in a fixed-dose combination for the treatment of hypercholesterolemia.
Topics: Anticholesteremic Agents; Atherosclerosis; Atorvastatin; Cardiovascular Diseases; Drug Combinations; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Risk Factors; Simvastatin | 2019 |
The 2018 Cholesterol Management Guidelines: Topics in Secondary ASCVD Prevention Clinicians Need to Know.
Topics: Aged; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Atherosclerosis; Cholesterol, LDL; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; PCSK9 Inhibitors; Secondary Prevention | 2019 |
Maximizing the benefits of cholesterol-lowering drugs.
Topics: Antibodies, Monoclonal; Cardiovascular Diseases; Cholesterol, LDL; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; PCSK9 Inhibitors; Proprotein Convertase 9 | 2019 |
Liptruzet: a combination of ezetimibe and atorvastatin.
Topics: Anticholesteremic Agents; Atorvastatin; Azetidines; Drug Combinations; Ezetimibe; Heptanoic Acids; Humans; Hypercholesterolemia; Hyperlipidemias; Pyrroles; Randomized Controlled Trials as Topic; Treatment Outcome | 2013 |
Effects of ezetimibe, simvastatin and ezetimibe/simvastatin on correlations between apolipoprotein B, LDL cholesterol and non-HDL cholesterol in patients with primary hypercholesterolemia.
Topics: Adult; Aged; Anticholesteremic Agents; Apolipoproteins B; Azetidines; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hypercholesterolemia; Linear Models; Male; Middle Aged; Predictive Value of Tests; Randomized Controlled Trials as Topic; Simvastatin; Triglycerides | 2013 |
[An inhibitor of intestinal cholesterol transporter].
Topics: Anticholesteremic Agents; Azetidines; Cholesterol; Ezetimibe; Humans; Hypercholesterolemia; Insulin Resistance; Intestinal Absorption | 2013 |
Non-cholesterol sterols and cholesterol metabolism in sitosterolemia.
Topics: Absorption; Atherosclerosis; ATP Binding Cassette Transporter, Subfamily G; ATP-Binding Cassette Transporters; Azetidines; Cholesterol; Disease Progression; Ezetimibe; Humans; Hypercholesterolemia; Intestinal Diseases; Kinetics; Lipid Metabolism, Inborn Errors; Membrane Proteins; Membrane Transport Proteins; Phytosterols; Sitosterols; Sterol O-Acyltransferase; Sterol O-Acyltransferase 2; Sterols; Xanthomatosis | 2013 |
Management of hypercholesterolemia in children.
Topics: Age Factors; Anticholesteremic Agents; Azetidines; Bile Acids and Salts; Cardiovascular Diseases; Child; Cholesterol; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Life Style; Mass Screening; Risk Factors | 2014 |
Toward individualized cholesterol-lowering treatment in end-stage renal disease.
Topics: Azetidines; Cardiovascular Diseases; Cholesterol, Dietary; Cholesterol, LDL; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestinal Absorption; Kidney Failure, Chronic; Phytosterols; Polyamines; Randomized Controlled Trials as Topic; Renal Dialysis; Risk Factors; Sevelamer | 2014 |
Effectiveness of combination therapy with statin and another lipid-modifying agent compared with intensified statin monotherapy: a systematic review.
Topics: Anticholesteremic Agents; Azetidines; Bile Acids and Salts; Cholesterol, LDL; Coronary Artery Disease; Drug Therapy, Combination; Ezetimibe; Fatty Acids, Omega-3; Fibric Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Medication Adherence; Niacin; Randomized Controlled Trials as Topic; Risk Factors; Treatment Outcome | 2014 |
Virtual screening for cholesterol absorption inhibitors.
Topics: Animals; Anticholesteremic Agents; Azetidines; Biological Transport; Cholesterol; Coronary Disease; Ezetimibe; Gene Expression; High-Throughput Screening Assays; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Membrane Proteins; Membrane Transport Proteins; Structure-Activity Relationship; User-Computer Interface | 2014 |
Sitosterolemia: diagnosis, investigation, and management.
Topics: Anemia, Hemolytic; Animals; Anticholesteremic Agents; Atherosclerosis; Azetidines; Ezetimibe; Humans; Hypercholesterolemia; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Mice; Phytosterols; Thrombocytopenia; Xanthomatosis | 2014 |
Resistance and intolerance to statins.
Topics: Anticholesteremic Agents; Azetidines; Benzimidazoles; Bile Acids and Salts; Cholesterol, LDL; Drug Resistance; Drug Therapy, Combination; Drug Tolerance; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Multidrug Resistance-Associated Protein 2; Pharmacogenetics; Polymorphism, Genetic | 2014 |
PCSK9 and its modulation.
Topics: Age Factors; Atherosclerosis; Azetidines; Cholesterol; Circadian Rhythm; Diet; Drugs, Chinese Herbal; Exercise; Ezetimibe; Fibric Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Insulin Resistance; Kidney Diseases; Liver Regeneration; Molecular Targeted Therapy; Proprotein Convertase 9; Proprotein Convertases; Risk Factors; Serine Endopeptidases | 2015 |
Safety of coadministration of ezetimibe and statins in patients with hypercholesterolaemia: a meta-analysis.
Topics: Anticholesteremic Agents; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Risk Factors; Treatment Outcome | 2015 |
'LDL-C' = LDL-C + Lp(a)-C: implications of achieved ultra-low LDL-C levels in the proprotein convertase subtilisin/kexin type 9 era of potent LDL-C lowering.
Topics: Animals; Cholesterol, LDL; Clinical Trials as Topic; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoprotein(a); Proprotein Convertase 9; Proprotein Convertases; Serine Endopeptidases; Treatment Outcome | 2015 |
The IMPROVE-IT study and ezetimibe.
Topics: Anticholesteremic Agents; Azetidines; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Simvastatin | 2015 |
Effect of Low-Density Lipoprotein Cholesterol Lowering by Ezetimibe/Simvastatin on Outcome Incidence: Overview, Meta-Analyses, and Meta-Regression Analyses of Randomized Trials.
Topics: Anticholesteremic Agents; Cardiovascular Diseases; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Incidence; Randomized Controlled Trials as Topic; Simvastatin; Treatment Outcome | 2015 |
The safety of ezetimibe and simvastatin combination for the treatment of hypercholesterolemia.
Topics: Animals; Anticholesteremic Agents; Drug Interactions; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Safety; Simvastatin | 2016 |
Recent advances in the pharmacological management of hypercholesterolaemia.
Topics: Anticholesteremic Agents; Cholesterol, LDL; Ezetimibe; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; PCSK9 Inhibitors | 2016 |
IMPROVE-IT: what have we learned?
Topics: Acute Coronary Syndrome; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Simvastatin; Treatment Outcome | 2016 |
Bempedoic Acid (ETC-1002): an Investigational Inhibitor of ATP Citrate Lyase.
Topics: Anticholesteremic Agents; ATP Citrate (pro-S)-Lyase; Cholesterol, LDL; Dicarboxylic Acids; Drug Therapy, Combination; Ezetimibe; Fatty Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia | 2016 |
Glycaemic Effects of Non-statin Lipid-Lowering Therapies.
Topics: Anticholesteremic Agents; Blood Glucose; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Ezetimibe; Fibric Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Lipid Metabolism; Meta-Analysis as Topic; Niacin; PCSK9 Inhibitors; Randomized Controlled Trials as Topic; Treatment Outcome | 2016 |
Hypercholesterolemia As a Risk Factor for Cardiovascular Disease: Current Controversial Therapeutic Management.
Topics: Animals; Anticholesteremic Agents; Atherosclerosis; Biological Transport; Cardiovascular Diseases; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Receptors, LDL; Risk Factors | 2016 |
[A new approach to the treatment of dyslipidemia].
Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol; Cholesterol, LDL; Clinical Trials as Topic; Coronary Disease; Diabetes Complications; Drug Therapy, Combination; Dyslipidemias; Ezetimibe; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Middle Aged; Practice Guidelines as Topic; Prognosis; Pyrroles; Risk Factors | 2008 |
Combination therapy in cholesterol reduction: focus on ezetimibe and statins.
Topics: Anticholesteremic Agents; Azetidines; Cardiovascular Diseases; Cholesterol; Cholesterol, LDL; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestinal Absorption; Liver; Practice Guidelines as Topic; Treatment Outcome | 2008 |
[Crosstalk between cholesterol homeostasis and drug metabolism].
Topics: Animals; Anticholesteremic Agents; Atherosclerosis; Azetidines; Bile; Cardiovascular Diseases; Cholesterol; Cholesterol, Dietary; Cytochrome P-450 Enzyme System; Ezetimibe; Feedback, Physiological; Homeostasis; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Liver; Pharmaceutical Preparations; Receptor Cross-Talk; Receptors, Cytoplasmic and Nuclear | 2008 |
Ezetimibe, a selective inhibitor of the transport of cholesterol.
Topics: Animals; Anticholesteremic Agents; Azetidines; Cholesterol; Clinical Trials as Topic; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Membrane Proteins; Membrane Transport Proteins; Mice; Protein Structure, Secondary | 2008 |
Novel nonstatin strategies to lower low-density lipoprotein cholesterol.
Topics: Animals; Anticholesteremic Agents; Azetidines; Benzimidazoles; Carrier Proteins; Cholesterol, LDL; Ezetimibe; Farnesyl-Diphosphate Farnesyltransferase; Humans; Hypercholesterolemia; Indoles; Oligonucleotides; Oxazepines; Piperidines; Proprotein Convertase 9; Proprotein Convertases; Pyridines; Serine Endopeptidases; Serine Proteinase Inhibitors | 2009 |
Ezetimibe monotherapy for cholesterol lowering in 2,722 people: systematic review and meta-analysis of randomized controlled trials.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Ezetimibe; Humans; Hypercholesterolemia; Randomized Controlled Trials as Topic; Treatment Outcome; Triglycerides | 2009 |
Cost effectiveness of ezetimibe in patients with cardiovascular disease and statin intolerance or contraindications: a Markov model.
Topics: Age Factors; Anticholesteremic Agents; Azetidines; Cardiovascular Diseases; Cholesterol, LDL; Cohort Studies; Contraindications; Cost-Benefit Analysis; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Markov Chains; Middle Aged; Models, Economic; Quality-Adjusted Life Years; United Kingdom | 2008 |
Update on patented cholesterol absorption inhibitors.
Topics: Absorption; Animals; Anticholesteremic Agents; Azetidines; Bile Acids and Salts; Biological Transport; Blood Proteins; Cholesterol; Ezetimibe; Heterocyclic Compounds; Humans; Hypercholesterolemia; Patents as Topic; Sterol Esterase; Sterol O-Acyltransferase | 2009 |
The impact of ezetimibe on endothelial function and other markers of cardiovascular risk.
Topics: Animals; Anticholesteremic Agents; Azetidines; Cardiovascular Diseases; Clinical Trials as Topic; Endothelium, Vascular; Ezetimibe; Humans; Hypercholesterolemia; Risk Factors | 2009 |
Ezetimibe/simvastatin.
Topics: Animals; Anticholesteremic Agents; Azetidines; Drug Combinations; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Simvastatin | 2009 |
Advancing therapy for hypercholesterolemia.
Topics: Azetidines; Bile Acids and Salts; Carrier Proteins; Cholesterol; Cholesterol Ester Transfer Proteins; Cholesterol, LDL; Ezetimibe; Farnesyl-Diphosphate Farnesyltransferase; Fatty Acids, Omega-3; Fenofibrate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestinal Absorption; Niacin | 2010 |
Systematic review on evidence of the effectiveness of cholesterol-lowering drugs.
Topics: Anticholesteremic Agents; Azetidines; Cholestyramine Resin; Coronary Disease; Drug Therapy, Combination; Evidence-Based Practice; Ezetimibe; Fatty Acids, Omega-3; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Niacin; Patient Selection; Phytosterols; Practice Guidelines as Topic; Primary Prevention; Risk Assessment; Risk Factors; Risk Reduction Behavior; Secondary Prevention; Treatment Outcome | 2010 |
Attainment of Canadian and European guidelines' lipid targets with atorvastatin plus ezetimibe vs. doubling the dose of atorvastatin.
Topics: Anticholesteremic Agents; Apolipoproteins B; Atorvastatin; Azetidines; C-Reactive Protein; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Multicenter Studies as Topic; Practice Guidelines as Topic; Pyrroles; Randomized Controlled Trials as Topic; Triglycerides | 2010 |
Ezetimibe and vascular inflammation.
Topics: Animals; Anticholesteremic Agents; Arteritis; Atherosclerosis; Azetidines; Cholesterol, LDL; Ezetimibe; Humans; Hypercholesterolemia; Meta-Analysis as Topic | 2011 |
Ezetimibe and reactive oxygen species.
Topics: Animals; Atherosclerosis; Azetidines; Cholesterol, LDL; Ezetimibe; Humans; Hypercholesterolemia; Oxidative Stress; Reactive Oxygen Species | 2011 |
Ezetimibe and vascular endothelial function.
Topics: Anticholesteremic Agents; Azetidines; Cardiovascular Diseases; Cholesterol, LDL; Endothelium, Vascular; Ezetimibe; Humans; Hypercholesterolemia | 2011 |
Lowering LDL cholesterol with margarine containing plant stanol/sterol esters: is it still relevant in 2011?
Topics: Anticholesteremic Agents; Azetidines; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus; Ezetimibe; Fibric Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipoproteinemia Type II; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Margarine; Micronutrients; Niacin; Phytosterols; Sitosterols; Triglycerides | 2011 |
Comparative efficacy of the addition of ezetimibe to statin vs statin titration in patients with hypercholesterolaemia: systematic review and meta-analysis.
Topics: Anticholesteremic Agents; Azetidines; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia | 2011 |
Clinical aspects of PCSK9.
Topics: Adolescent; Animals; Azetidines; Diabetes Mellitus, Type 2; Ezetimibe; Female; Fibric Acids; Genes, Dominant; Humans; Hypercholesterolemia; Lipid Metabolism; Male; Mice; Mutation; Nutritional Status; Phenotype; Proprotein Convertase 9; Proprotein Convertases; Protease Inhibitors; Receptors, LDL; Serine Endopeptidases | 2011 |
Where does the interplay between cholesterol absorption and synthesis in the context of statin and/or ezetimibe treatment stand today?
Topics: Anticholesteremic Agents; Atherosclerosis; Azetidines; Cholesterol; Evidence-Based Medicine; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestinal Absorption; Intestinal Mucosa; Intestines; Liver; Treatment Outcome | 2011 |
Intestinal sterol transporters and cholesterol absorption inhibition.
Topics: Animals; Anticholesteremic Agents; Azetidines; Biological Transport; Cholesterol; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestinal Absorption; Randomized Controlled Trials as Topic; Sterol O-Acyltransferase | 2011 |
Ezetimibe/simvastatin: a guide to its clinical use in hypercholesterolemia.
Topics: Animals; Anticholesteremic Agents; Azetidines; Drug Combinations; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Practice Guidelines as Topic; Simvastatin | 2012 |
Ezetimibe--a new approach in hypercholesterolemia management.
Topics: Animals; Anticholesteremic Agents; Azetidines; Disease Management; Ezetimibe; Humans; Hypercholesterolemia; Intestinal Absorption | 2011 |
Lipid-altering efficacy of ezetimibe plus statin and statin monotherapy and identification of factors associated with treatment response: a pooled analysis of over 21,000 subjects from 27 clinical trials.
Topics: Aged; Anticholesteremic Agents; Azetidines; Biomarkers; Cholesterol, LDL; Clinical Trials as Topic; Drug Therapy, Combination; Evidence-Based Medicine; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Treatment Outcome | 2012 |
Effect of high-dose statin versus low-dose statin plus ezetimibe on endothelial function: a meta-analysis of randomized trials.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, Dietary; Drug Therapy, Combination; Endothelium, Vascular; Ezetimibe; Gastrointestinal Agents; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestinal Absorption; Randomized Controlled Trials as Topic; Vasodilation | 2012 |
The ezetimibe controversy - can this be resolved by comparing the clinical trials with simvastatin and ezetimibe alone and together?
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Clinical Trials as Topic; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Simvastatin | 2012 |
Cholesterol absorption inhibitors for the treatment of hypercholesterolaemia.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol; Clinical Trials as Topic; Drug Synergism; Ezetimibe; Humans; Hypercholesterolemia; Phytosterols; Sterol O-Acyltransferase; Sterol O-Acyltransferase 2; Structure-Activity Relationship | 2002 |
Ezetimibe.
Topics: Animals; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Ezetimibe; Humans; Hypercholesterolemia | 2002 |
The future direction of cholesterol-lowering therapy.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Clinical Trials as Topic; Drug Therapy, Combination; Ezetimibe; Fluorobenzenes; Forecasting; Humans; Hypercholesterolemia; Pyrimidines; Rosuvastatin Calcium; Sulfonamides | 2002 |
[Combination therapy of hypercholesterolemia].
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Cholestyramine Resin; Combined Modality Therapy; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Margarine; Phytosterols | 2002 |
[The best of clinical pharmacology in 2002].
Topics: Anticholesteremic Agents; Antihypertensive Agents; Azetidines; Cardiovascular Diseases; Ezetimibe; Hormone Replacement Therapy; Humans; Hydrazones; Hypercholesterolemia; Losartan; Myocardial Infarction; Natriuretic Agents; Natriuretic Peptide, Brain; Neovascularization, Physiologic; Nicorandil; Pyridazines; Randomized Controlled Trials as Topic; Simendan; Vasodilator Agents | 2003 |
Ezetimibe.
Topics: Anticholesteremic Agents; Azetidines; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia | 2003 |
Ezetimibe for management of hypercholesterolemia.
Topics: Animals; Azetidines; Clinical Trials as Topic; Disease Management; Ezetimibe; Humans; Hypercholesterolemia | 2003 |
Perspectives in cholesterol-lowering therapy: the role of ezetimibe, a new selective inhibitor of intestinal cholesterol absorption.
Topics: Adolescent; Anticholesteremic Agents; Azetidines; Cholesterol; Cholesterol, LDL; Clinical Trials as Topic; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestinal Absorption; Male; Middle Aged; Myocardial Infarction; Treatment Outcome | 2003 |
The place of ezetimibe in clinical practice.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol; Drug Interactions; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipoproteinemia Type II | 2003 |
Clinical use of ezetimibe.
Topics: Anticholesteremic Agents; Azetidines; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Practice Guidelines as Topic; Randomized Controlled Trials as Topic | 2003 |
Ezetimibe and cholesterol absorption.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, Dietary; Chylomicrons; Ezetimibe; Homeostasis; Humans; Hypercholesterolemia; Intestinal Absorption | 2003 |
Pharmacology and therapeutics of ezetimibe (SCH 58235), a cholesterol-absorption inhibitor.
Topics: Animals; Anticholesteremic Agents; Azetidines; Clinical Trials as Topic; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Lipoproteins | 2003 |
Ezetimibe: a selective cholesterol absorption inhibitor.
Topics: Animals; Anticholesteremic Agents; Azetidines; Clinical Trials as Topic; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Intestinal Absorption | 2003 |
[Cardiovascular risk factor reduction. Cholesterol absorption inhibitors: a new action principle].
Topics: Anticholesteremic Agents; Azetidines; Cardiovascular Diseases; Cholesterol, Dietary; Drug Interactions; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Intestinal Absorption; Risk Factors | 2003 |
Cholesterol absorption inhibitors: a closer look.
Topics: Anticholesteremic Agents; Azetidines; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Patient Selection; Phytosterols; Treatment Outcome | 2003 |
Ezetimibe: a first-in-class, novel cholesterol absorption inhibitor.
Topics: Animals; Anticholesteremic Agents; Azetidines; Biological Availability; Ezetimibe; Half-Life; Humans; Hypercholesterolemia; Intestinal Absorption; Randomized Controlled Trials as Topic; Species Specificity | 2003 |
Ezetimibe.
Topics: Animals; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Clinical Trials as Topic; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia | 2003 |
Hypolipidemic therapy and cholesterol absorption.
Topics: Allylamine; Anticholesteremic Agents; Azetidines; Cholesterol; Colesevelam Hydrochloride; Ezetimibe; Humans; Hypercholesterolemia; Intestinal Absorption | 2004 |
Ezetimibe: a novel option for lowering cholesterol.
Topics: Anticholesteremic Agents; Azetidines; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Randomized Controlled Trials as Topic | 2003 |
Primary hypercholesterolemia: genetic causes and treatment of five monogenic disorders.
Topics: Anticholesteremic Agents; Azetidines; Cholestyramine Resin; Diet, Fat-Restricted; Ezetimibe; Genetic Predisposition to Disease; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Receptors, LDL | 2003 |
Lipid lowering activity of drugs affecting cholesterol absorption.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol; Cholesterol, Dietary; Ezetimibe; Humans; Hypercholesterolemia; Intestinal Absorption; Molecular Biology; Sterols | 2004 |
[Ezetimibe: from pharmacology to clinical trials].
Topics: Animals; Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol, LDL; Clinical Trials as Topic; Coronary Disease; Depression, Chemical; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Heptanoic Acids; Hypercholesterolemia; Intestinal Absorption; Liver; Lovastatin; Pravastatin; Pyrroles; Safety; Simvastatin; Treatment Outcome | 2003 |
Medical lipid-regulating therapy: current evidence, ongoing trials and future developments.
Topics: Anticholesteremic Agents; Azetidines; Carrier Proteins; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Ezetimibe; Glycoproteins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Randomized Controlled Trials as Topic; Risk Factors; Treatment Outcome | 2004 |
[New treatment option for decreasing blood cholesterol level--clinical significance of inhibition of both, cholesterol absorption and synthesis].
Topics: Anticholesteremic Agents; Azetidines; Cholesterol; Cholesterol, LDL; Drug Therapy, Combination; Drug Tolerance; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestinal Absorption; Liver | 2004 |
Current management of severe homozygous hypercholesterolaemias.
Topics: Adolescent; Adult; Apolipoproteins B; Azetidines; Blood Component Removal; Child; Cholesterol; Coronary Disease; Ezetimibe; Female; Genes, Recessive; Genetic Therapy; Homozygote; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipid Metabolism; Liver Transplantation; Male; Models, Genetic; Mutation; Pregnancy; Time Factors | 2004 |
[Ezetimib].
Topics: Anticholesteremic Agents; Arteriosclerosis; Azetidines; Coronary Disease; Ezetimibe; Humans; Hypercholesterolemia; Hyperlipoproteinemias | 2004 |
[The role of intestinal absorption blockade in hypercholesterolemia treatment].
Topics: Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol; Ezetimibe; Heptanoic Acids; Humans; Hypercholesterolemia; Intestinal Obstruction; Pyrroles | 2004 |
Ezetimibe: a novel cholesterol-lowering agent that highlights novel physiologic pathways.
Topics: Animals; Anticholesteremic Agents; Azetidines; Cholesterol, Dietary; Disease Progression; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestinal Absorption | 2004 |
Ezetimibe/Simvastatin: a review of its use in the management of hypercholesterolemia.
Topics: Animals; Anticholesteremic Agents; Azetidines; Cost-Benefit Analysis; Drug Combinations; Drug Interactions; Ezetimibe; Humans; Hypercholesterolemia; Randomized Controlled Trials as Topic; Simvastatin | 2004 |
[Selective cholesterol absorption inhibition as a new prospect in treatment of hypercholesterolemia].
Topics: Anticholesteremic Agents; Azetidines; Clinical Trials as Topic; Ezetimibe; Humans; Hypercholesterolemia | 2005 |
Cholesterol and plant sterol absorption: recent insights.
Topics: Absorption; Anticholesteremic Agents; ATP-Binding Cassette Transporters; Azetidines; Cholesterol; Diet; Ezetimibe; Humans; Hypercholesterolemia; Membrane Proteins; Membrane Transport Proteins; Microvilli; Phytosterols; Proteins | 2005 |
Lipid altering-efficacy of ezetimibe co-administered with simvastatin compared with rosuvastatin: a meta-analysis of pooled data from 14 clinical trials.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Clinical Trials as Topic; Drug Therapy, Combination; Ezetimibe; Fluorobenzenes; Humans; Hypercholesterolemia; Pyrimidines; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Treatment Outcome | 2005 |
Enhanced hypercholesterolemia therapy: the ezetimibe/simvastatin tablet.
Topics: Anticholesteremic Agents; Azetidines; Drug Combinations; Ezetimibe; Humans; Hypercholesterolemia; Randomized Controlled Trials as Topic; Simvastatin | 2005 |
[New results in the management of hypercholesterolemia].
Topics: Anticholesteremic Agents; Azetidines; C-Reactive Protein; Carrier Proteins; Cholesterol Ester Transfer Proteins; Cholesterol, LDL; Clinical Trials as Topic; Coronary Disease; Drug Therapy, Combination; Enzyme Inhibitors; Evidence-Based Medicine; Ezetimibe; Glycoproteins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Inflammation; Practice Guidelines as Topic; Sterol O-Acyltransferase | 2005 |
Ezetimibe: rationale and role in the management of hypercholesterolemia.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Ezetimibe; Humans; Hypercholesterolemia; Intestinal Absorption | 2006 |
Reaching goal in hypercholesterolaemia: dual inhibition of cholesterol synthesis and absorption with simvastatin plus ezetimibe.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Simvastatin | 2006 |
Consistency of lipid-altering effects of ezetimibe/simvastatin across gender, race, age, baseline low density lipoprotein cholesterol levels, and coronary heart disease status: results of a pooled retrospective analysis.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Azetidines; Cholesterol, LDL; Clinical Trials, Phase III as Topic; Coronary Disease; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hypercholesterolemia; Lipoproteins; Male; Middle Aged; Retrospective Studies; Risk Factors; Sex Factors; Simvastatin; Treatment Outcome | 2006 |
[Intensive cholesterol lowering therapy to reduce cardiovascular risk].
Topics: Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol, LDL; Clofibric Acid; Coronary Artery Disease; Drug Therapy, Combination; Ezetimibe; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Pyrroles | 2006 |
Comparison of the lipid-modifying efficacy and safety profiles of ezetimibe coadministered with simvastatin in older versus younger patients with primary hypercholesterolemia: a post Hoc analysis of subpopulations from three pooled clinical trials.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anticholesteremic Agents; Azetidines; C-Reactive Protein; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hypercholesterolemia; Lipids; Male; Middle Aged; Randomized Controlled Trials as Topic; Simvastatin | 2006 |
Combination therapy with ezetimibe and simvastatin to achieve aggressive LDL reduction.
Topics: Anticholesteremic Agents; Atorvastatin; Azetidines; C-Reactive Protein; Cardiovascular Diseases; Drug Therapy, Combination; Ezetimibe; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestinal Absorption; Lipoproteins, LDL; Phytosterols; Pravastatin; Pyrroles; Simvastatin | 2006 |
[Lowering cholesterol: how low is low enough?].
Topics: Anticholesteremic Agents; Azetidines; Cardiovascular Diseases; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia | 2006 |
Cholesterol absorption inhibitors as a therapeutic option for hypercholesterolaemia.
Topics: Acetyl-CoA C-Acyltransferase; Animals; Anticholesteremic Agents; Atherosclerosis; Azetidines; Bile Acids and Salts; Carrier Proteins; Cholesterol, Dietary; Drugs, Investigational; Ezetimibe; Humans; Hypercholesterolemia; Intestinal Absorption; Phytosterols | 2006 |
Non-low-density lipoprotein cholesterol-associated actions of ezetimibe: an overview.
Topics: Azetidines; Ezetimibe; Humans; Hypercholesterolemia; Hypolipidemic Agents | 2006 |
[Cholesterol absorption as a target for the treatment of hypercholesterolemia].
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, Dietary; Cholesterol, LDL; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestinal Absorption | 2006 |
[Ezetimibe--intestinal cholesterol absorbtion inhibitor].
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, Dietary; Cholesterol, HDL; Cholesterol, LDL; Drug Interactions; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestinal Absorption; Intestinal Mucosa; Intestines; Liver | 2006 |
[Change in the cholesterol metabolism associated with the combined inhibition of synthesis and absorption].
Topics: Anticholesteremic Agents; Azetidines; Biomarkers; Cholestanol; Cholesterol; Cholesterol, Dietary; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestinal Absorption; Phytosterols; Sitosterols | 2007 |
Ezetimibe: an update on the mechanism of action, pharmacokinetics and recent clinical trials.
Topics: Anticholesteremic Agents; Area Under Curve; Azetidines; Cholesterol; Clinical Trials as Topic; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Molecular Structure; Treatment Outcome | 2007 |
Zetia: inhibition of Niemann-Pick C1 Like 1 (NPC1L1) to reduce intestinal cholesterol absorption and treat hyperlipidemia.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Ezetimibe; Humans; Hypercholesterolemia; Hyperlipidemias; Intestinal Absorption; Intestinal Mucosa; Intestines; Membrane Proteins; Membrane Transport Proteins; Niemann-Pick Diseases | 2007 |
Meta-analysis of the cholesterol-lowering effect of ezetimibe added to ongoing statin therapy.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoproteins; Placebos; Randomized Controlled Trials as Topic; Triglycerides | 2007 |
The pharmacologic elegance of inhibiting cholesterol absorption and synthesis while providing a homeostatic balance.
Topics: Animals; Anticholesteremic Agents; Azetidines; Cholesterol; Ezetimibe; Homeostasis; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestinal Absorption; Liver | 2007 |
Ezetimibe-associated adverse effects: what the clinician needs to know.
Topics: Anticholesteremic Agents; Azetidines; Chemical and Drug Induced Liver Injury; Drug Interactions; Ezetimibe; Humans; Hypercholesterolemia; Muscular Diseases; Treatment Outcome | 2008 |
Ezetimibe: cholesterol lowering and beyond.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol; Controlled Clinical Trials as Topic; Coronary Disease; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia | 2008 |
Ezetimibe for the treatment of hypercholesterolaemia: a systematic review and economic evaluation.
Topics: Anticholesteremic Agents; Azetidines; Cost-Benefit Analysis; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic | 2008 |
Review of side-effect profile of combination ezetimibe and statin therapy in randomized clinical trials.
Topics: Anticholesteremic Agents; Azetidines; Drug Therapy, Combination; Ezetimibe; Gastrointestinal Diseases; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Incidence; Lipids; Muscular Diseases; Randomized Controlled Trials as Topic; Risk Factors | 2008 |
Novel approaches to lipid lowering: what is on the horizon?
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Clinical Trials as Topic; Coronary Disease; Drug Evaluation; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Prognosis | 2001 |
Therapies on the horizon for cholesterol reduction.
Topics: Acetamides; Acetates; Anticholesteremic Agents; Azetidines; Carrier Proteins; Cholestyramine Resin; Ezetimibe; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxysteroid Dehydrogenases; Hypercholesterolemia; Membrane Glycoproteins; Pyrimidines; Rosuvastatin Calcium; Sterol O-Acyltransferase; Sulfonamides; Sulfonic Acids | 2001 |
Cholesterol absorption inhibition: a strategy for cholesterol-lowering therapy.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol; Cholesterol, LDL; Coronary Disease; Ezetimibe; Humans; Hypercholesterolemia | 2001 |
An investigative look: selective cholesterol absorption inhibitors--embarking on a new standard of care.
Topics: Anticholesteremic Agents; Azetidines; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia | 2002 |
Selective cholesterol absorption inhibition: a novel strategy in lipid-lowering management.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Coronary Disease; Europe; Ezetimibe; Humans; Hypercholesterolemia; Practice Guidelines as Topic | 2002 |
190 trial(s) available for ezetimibe and Elevated Cholesterol
Article | Year |
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Main differences between two highly effective lipid-lowering therapies in subclasses of lipoproteins in patients with acute myocardial infarction.
Topics: Aged; Atherosclerosis; Cholesterol; Cholesterol, LDL; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lipoproteins; Liver; Male; Middle Aged; Rosuvastatin Calcium; Simvastatin; ST Elevation Myocardial Infarction | 2021 |
Insulin Prevents Hypercholesterolemia by Suppressing 12α-Hydroxylated Bile Acids.
Topics: Animals; Bile Acids and Salts; Cholesterol, LDL; Cross-Over Studies; Diabetes Mellitus, Type 1; Ezetimibe; Humans; Hypercholesterolemia; Hyperlipidemias; Insulin; Liver; Mice; Receptor, Insulin; Simvastatin; Steroid 12-alpha-Hydroxylase | 2022 |
Serum MIG6 concentration is increased by cholesterol-lowering treatment in patients with type 2 diabetes mellitus and hypercholesterolemia.
Topics: Adaptor Proteins, Signal Transducing; Anticholesteremic Agents; Cholesterol, LDL; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Prospective Studies; Rosuvastatin Calcium; Tumor Suppressor Proteins | 2022 |
Effect of 1PC111, a Fixed-dose Combination of Pitavastatin and Ezetimibe, Versus Pitavastatin or Ezetimibe Monotherapy on Lipid Profiles in Patients With Hypercholesterolemia or Mixed Dyslipidemia: A Randomized, Double-blind, Multicenter, Phase III Study.
Topics: Aged; Cholesterol, LDL; Dyslipidemias; Ezetimibe; Humans; Hypercholesterolemia | 2022 |
Efficacy and Tolerability of Ezetimibe/Atorvastatin Fixed-dose Combination Versus Atorvastatin Monotherapy in Hypercholesterolemia: A Phase III, Randomized, Active-controlled Study in Chinese Patients.
Topics: Anticholesteremic Agents; Atorvastatin; China; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Treatment Outcome | 2022 |
A Multicenter, Randomized, Double-blind, Active-controlled, Factorial Design, Phase III Clinical Trial to Evaluate the Efficacy and Safety of Combination Therapy of Pitavastatin and Ezetimibe Versus Monotherapy of Pitavastatin in Patients With Primary Hyp
Topics: Anticholesteremic Agents; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Dyslipidemias; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Treatment Outcome | 2022 |
Potential Cardiovascular Events Avoided with Bempedoic Acid Plus Ezetimibe Fixed-Dose Combination Compared with Ezetimibe Alone in Patients with Atherosclerotic Cardiovascular Disease Taking Maximally Tolerated Statins.
Topics: Anticholesteremic Agents; Atherosclerosis; Azetidines; Cardiovascular Diseases; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Quality of Life; Treatment Outcome | 2023 |
Small Interfering RNA to Reduce Lipoprotein(a) in Cardiovascular Disease.
Topics: Anticholesteremic Agents; Atherosclerosis; Cardiovascular Diseases; Double-Blind Method; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoprotein(a); Liver; PCSK9 Inhibitors; RNA, Small Interfering | 2022 |
Effects of rosuvastatin/ezetimibe on senescence of CD8+ T-cell in type 2 diabetic patients with hypercholesterolemia: A study protocol.
Topics: CD8-Positive T-Lymphocytes; Cholesterol, LDL; Cytokines; Diabetes Mellitus, Type 2; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Inflammation; Randomized Controlled Trials as Topic; Rosuvastatin Calcium | 2022 |
Efficacy and Safety of Single-Pill Combination of Rosuvastatin and Ezetimibe in Chinese Patients with Primary Hypercholesterolemia Inadequately Controlled by Statin Treatment (ROZEL): A Randomized, Double-Blind, Double Dummy, Active-Controlled Phase 3 Cli
Topics: Anticholesteremic Agents; Cholesterol, LDL; Double-Blind Method; Drug Combinations; East Asian People; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Rosuvastatin Calcium; Treatment Outcome | 2023 |
Effectiveness of low-intensity atorvastatin 5 mg and ezetimibe 10 mg combination therapy compared with moderate-intensity atorvastatin 10 mg monotherapy: A randomized, double-blinded, multi-center, phase III study.
Topics: Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Pyrroles; Treatment Outcome | 2023 |
The Efficacy and Safety of Moderate-Intensity Rosuvastatin with Ezetimibe versus High-Intensity Rosuvastatin in High Atherosclerotic Cardiovascular Disease Risk Patients with Type 2 Diabetes Mellitus: A Randomized, Multicenter, Open, Parallel, Phase 4 Stu
Topics: Anticholesteremic Agents; Atherosclerosis; Cardiovascular Diseases; Cholesterol, LDL; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Rosuvastatin Calcium | 2023 |
Ezetimibe and Rosuvastatin Combination Treatment Can Reduce the Dose of Rosuvastatin Without Compromising Its Lipid-lowering Efficacy.
Topics: Anticholesteremic Agents; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Lipids; Rosuvastatin Calcium; Treatment Outcome | 2019 |
Evolocumab vs. Ezetimibe in Statin-Intolerant Hyperlipidemic Japanese Patients: Phase 3 GAUSS-4 Trial.
Topics: Antibodies, Monoclonal, Humanized; Cholesterol, LDL; Dose-Response Relationship, Drug; Double-Blind Method; Drug Monitoring; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Japan; Male; Middle Aged; Outcome Assessment, Health Care | 2020 |
Goal achievement of HbA1c and LDL-cholesterol in a randomized trial comparing colesevelam with ezetimibe: GOAL-RCT.
Topics: Aged; Anticholesteremic Agents; Cholesterol, LDL; Colesevelam Hydrochloride; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Ezetimibe; Glycated Hemoglobin; Goals; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Middle Aged; Treatment Outcome | 2020 |
Low dose of ROSuvastatin in combination with EZEtimibe effectively and permanently reduce low density lipoprotein cholesterol concentration independently of timing of administration (ROSEZE): A randomized, crossover study - preliminary results.
Topics: Cholesterol, LDL; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Rosuvastatin Calcium; Treatment Outcome | 2021 |
Combination of bempedoic acid, ezetimibe, and atorvastatin in patients with hypercholesterolemia: A randomized clinical trial.
Topics: Anticholesteremic Agents; Atorvastatin; Dicarboxylic Acids; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Fatty Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Middle Aged; Treatment Outcome | 2021 |
Evaluation of two highly effective lipid-lowering therapies in subjects with acute myocardial infarction.
Topics: Anticholesteremic Agents; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipid Metabolism; Lipids; Male; Middle Aged; Myocardial Infarction; Rosuvastatin Calcium; Simvastatin; ST Elevation Myocardial Infarction | 2021 |
Effects of Fixed-dose Combination of Low-intensity Rosuvastatin and Ezetimibe Versus Moderate-intensity Rosuvastatin Monotherapy on Lipid Profiles in Patients With Hypercholesterolemia: A Randomized, Double-blind, Multicenter, Phase III Study.
Topics: Anticholesteremic Agents; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Rosuvastatin Calcium; Treatment Outcome | 2021 |
Thyroid Hormone Status in Sitosterolemia Is Modified by Ezetimibe.
Topics: Adolescent; Adult; Anticholesteremic Agents; Cholestanol; Cholestenones; Cholesterol; Ezetimibe; Female; Humans; Hypercholesterolemia; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Male; Middle Aged; Phytosterols; Sitosterols; Thyrotropin; Thyroxine; Triiodothyronine; Young Adult | 2017 |
The impact of the time of drug administration on the effectiveness of combined treatment of hypercholesterolemia with Rosuvastatin and Ezetimibe (RosEze): study protocol for a randomized controlled trial.
Topics: Anticholesteremic Agents; Biomarkers; Cholesterol, LDL; Clinical Protocols; Cross-Over Studies; Drug Administration Schedule; Drug Combinations; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Poland; Research Design; Rosuvastatin Calcium; Time Factors; Treatment Outcome | 2017 |
Efficacy and Safety of Alirocumab Versus Ezetimibe Over 2 Years (from ODYSSEY COMBO II).
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Cholesterol, LDL; Clinical Decision-Making; Coronary Disease; Dose-Response Relationship, Drug; Double-Blind Method; Ezetimibe; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Injections, Subcutaneous; Male; Medication Adherence; Middle Aged; Time Factors; Treatment Outcome | 2017 |
A Phase III, Multicenter, Randomized, Double-blind, Active Comparator Clinical Trial to Compare the Efficacy and Safety of Combination Therapy With Ezetimibe and Rosuvastatin Versus Rosuvastatin Monotherapy in Patients With Hypercholesterolemia: I-ROSETTE
Topics: Aged; Anticholesteremic Agents; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Republic of Korea; Rosuvastatin Calcium; Treatment Outcome | 2018 |
Efficacy and Safety of Ezetimibe and Rosuvastatin Combination Therapy Versus Those of Rosuvastatin Monotherapy in Patients With Primary Hypercholesterolemia.
Topics: Aged; Anticholesteremic Agents; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Rosuvastatin Calcium; Treatment Outcome | 2018 |
Efficacy and safety of bempedoic acid added to ezetimibe in statin-intolerant patients with hypercholesterolemia: A randomized, placebo-controlled study.
Topics: Aged; Biomarkers; Canada; Cholesterol, LDL; Dicarboxylic Acids; Double-Blind Method; Down-Regulation; Drug Therapy, Combination; Europe; Ezetimibe; Fatty Acids; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Male; Middle Aged; Time Factors; Treatment Outcome; United States | 2018 |
Cost-effectiveness and Budget Impact of Treatment with Evolocumab Versus Statins and Ezetimibe for Hypercholesterolemia in Spain.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Cost-Benefit Analysis; Drug Costs; Ezetimibe; Female; Follow-Up Studies; Forecasting; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Incidence; Male; Middle Aged; Spain; Treatment Outcome | 2018 |
Lower On-Treatment Low-Density Lipoprotein Cholesterol and Major Adverse Cardiovascular Events in Women and Men: Pooled Analysis of 10 ODYSSEY Phase 3 Alirocumab Trials.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Biomarkers; Cardiovascular Diseases; Cholesterol, LDL; Dose-Response Relationship, Drug; Double-Blind Method; Ezetimibe; Female; Humans; Hypercholesterolemia; Incidence; Male; Middle Aged; Sex Distribution; Sex Factors; Treatment Outcome; United Kingdom | 2018 |
Bempedoic acid plus ezetimibe fixed-dose combination in patients with hypercholesterolemia and high CVD risk treated with maximally tolerated statin therapy.
Topics: Aged; Anticholesteremic Agents; Biomarkers; Cardiovascular Diseases; Cholesterol, LDL; Dicarboxylic Acids; Double-Blind Method; Down-Regulation; Drug Combinations; Ezetimibe; Fatty Acids; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Time Factors; Treatment Outcome; United States | 2020 |
The Bioequivalence and Effect of Food on the Pharmacokinetics of a Fixed-Dose Combination Tablet Containing Rosuvastatin and Ezetimibe in Healthy Japanese Subjects.
Topics: Administration, Oral; Adult; Anticholesteremic Agents; Cross-Over Studies; Drug Combinations; Drug Therapy, Combination; Ezetimibe; Fasting; Female; Food-Drug Interactions; Healthy Volunteers; Humans; Hypercholesterolemia; Japan; Male; Middle Aged; Postprandial Period; Rosuvastatin Calcium; Tablets; Therapeutic Equivalency; Young Adult | 2019 |
Impact of adding ezetimibe to statin to achieve low-density lipoprotein cholesterol goal (from the Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation [COURAGE] trial).
Topics: Aged; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ezetimibe; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Myocardial Revascularization; Retrospective Studies; Secondary Prevention; Simvastatin; Treatment Outcome | 2013 |
Are there differences in LDL-C target value attainment in Austrian federal states? Yes!
Topics: Aged; Anticholesteremic Agents; Austria; Azetidines; Cholesterol, LDL; Cross-Sectional Studies; Drug Resistance; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Longitudinal Studies; Male; Middle Aged; Retreatment; Topography, Medical | 2013 |
Observational study of ezetimibe discontinuation in primary care practices in the UK.
Topics: Adult; Anticholesteremic Agents; Azetidines; Cholesterol; Databases, Factual; Drug Substitution; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Primary Health Care; Risk Factors; Time Factors; United Kingdom | 2013 |
Efficacy of combination of Ezetimibe 10 mg and rosuvastatin 2.5 mg versus rosuvastatin 5 mg monotherapy for hypercholesterolemia in patients with type 2 diabetes.
Topics: Aged; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Diabetes Mellitus, Type 2; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Ezetimibe; Female; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoproteins, LDL; Male; Middle Aged; Pyrimidines; Rosuvastatin Calcium; Sulfonamides; Treatment Outcome; Triglycerides | 2013 |
Efficacy and safety of ezetimibe added to atorvastatin versus atorvastatin uptitration or switching to rosuvastatin in patients with primary hypercholesterolemia.
Topics: Aged; Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hypercholesterolemia; Logistic Models; Male; Middle Aged; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Sulfonamides | 2013 |
RESEARCH (Recognized effect of Statin and ezetimibe therapy for achieving LDL-C Goal), a randomized, doctor-oriented, multicenter trial to compare the effects of higher-dose statin versus ezetimibe-plus-statin on the serum LDL-C concentration of Japanese
Topics: Age Factors; Aged; Anticholesteremic Agents; Apolipoproteins B; Azetidines; Cholesterol, LDL; Diabetes Mellitus, Type 2; Drug Administration Schedule; Drug Therapy, Combination; Ezetimibe; Female; Glycated Hemoglobin; Humans; Hypercholesterolemia; Male; Middle Aged; Sex Factors; Simvastatin | 2013 |
Comparison of the effect of simvastatin versus simvastatin/ezetimibe versus rosuvastatin on markers of inflammation and oxidative stress in subjects with hypercholesterolemia.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Adult; Aged; Azetidines; Cholesterol, LDL; Dinoprost; Drug Combinations; Ezetimibe; Female; Fluorobenzenes; Humans; Hypercholesterolemia; Lipoproteins, LDL; Male; Middle Aged; Oxidative Stress; Pyrimidines; Rosuvastatin Calcium; Simvastatin; Sulfonamides | 2013 |
Efficacy, safety and effect on biomarkers related to cholesterol and lipoprotein metabolism of rosuvastatin 10 or 20 mg plus ezetimibe 10 mg vs. simvastatin 40 or 80 mg plus ezetimibe 10 mg in high-risk patients: Results of the GRAVITY randomized study.
Topics: Absorption; Adult; Atherosclerosis; Azetidines; Biomarkers; Cholesterol, LDL; Coronary Disease; Drug Administration Schedule; Ezetimibe; Female; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lipoproteins; Male; Pyrimidines; Risk; Rosuvastatin Calcium; Simvastatin; Sitosterols; Sulfonamides; Treatment Outcome | 2014 |
Atorvastatin 10 mg plus ezetimibe versus titration to atorvastatin 40 mg: attainment of European and Canadian guideline lipid targets in high-risk subjects ≥65 years.
Topics: Aged; Anticholesteremic Agents; Atherosclerosis; Atorvastatin; Azetidines; Canada; Cholesterol, LDL; Double-Blind Method; Europe; Ezetimibe; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Practice Guidelines as Topic; Pyrroles; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Treatment Outcome | 2014 |
Design and rationale of the GAUSS-2 study trial: a double-blind, ezetimibe-controlled phase 3 study of the efficacy and tolerability of evolocumab (AMG 145) in subjects with hypercholesterolemia who are intolerant of statin therapy.
Topics: Administration, Oral; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Apolipoproteins A; Apolipoproteins B; Azetidines; Cholesterol; Cholesterol, LDL; Contraindications; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Injections, Subcutaneous; Male; Middle Aged; Proprotein Convertase 9; Proprotein Convertases; Serine Endopeptidases; Triglycerides | 2014 |
Rationale and design of LAPLACE-2: a phase 3, randomized, double-blind, placebo- and ezetimibe-controlled trial evaluating the efficacy and safety of evolocumab in subjects with hypercholesterolemia on background statin therapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Azetidines; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Dyslipidemias; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Treatment Outcome; Young Adult | 2014 |
Effects of lipid-lowering drugs on high-density lipoprotein subclasses in healthy men-a randomized trial.
Topics: Adipokines; Adult; Azetidines; Biomarkers; Drug Therapy, Combination; Ezetimibe; Glucose; Healthy Volunteers; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lipoproteins, HDL; Male; Simvastatin | 2014 |
Impact of the ENHANCE trial on the use of ezetimibe in the United States and Canada.
Topics: Anticholesteremic Agents; Atherosclerosis; Azetidines; Canada; Cholesterol; Disease Progression; Dose-Response Relationship, Drug; Drug Costs; Drug Prescriptions; Ezetimibe; Follow-Up Studies; Humans; Hypercholesterolemia; Prevalence; Retrospective Studies; Time Factors; Treatment Outcome; United States | 2014 |
Effect of evolocumab or ezetimibe added to moderate- or high-intensity statin therapy on LDL-C lowering in patients with hypercholesterolemia: the LAPLACE-2 randomized clinical trial.
Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Atorvastatin; Azetidines; Double-Blind Method; Drug Therapy, Combination; Dyslipidemias; Ezetimibe; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Treatment Outcome | 2014 |
Monotherapy with the PCSK9 inhibitor alirocumab versus ezetimibe in patients with hypercholesterolemia: results of a 24 week, double-blind, randomized Phase 3 trial.
Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Azetidines; Double-Blind Method; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Proprotein Convertase 9; Proprotein Convertases; Serine Endopeptidases | 2014 |
Simvastatin but not ezetimibe reduces sympathetic activity despite similar reductions in cholesterol levels.
Topics: Adult; Anticholesteremic Agents; Azetidines; Baroreflex; Cholesterol; Cholesterol, HDL; Double-Blind Method; Ezetimibe; Female; Heart Rate; Hemodynamics; Humans; Hypercholesterolemia; Male; Middle Aged; Muscle, Skeletal; Simvastatin; Sympathetic Nervous System | 2014 |
Fixed-dose combination ezetimibe+atorvastatin lowers LDL-C equivalent to co-administered components in randomized trials: use of a dose-response model.
Topics: Aged; Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Middle Aged | 2015 |
Ezetimibe reduces plant sterol accumulation and favorably increases platelet count in sitosterolemia.
Topics: Adolescent; Adult; Anticholesteremic Agents; Azetidines; Canada; Cholesterol; Erythrocyte Count; Ezetimibe; Female; Humans; Hypercholesterolemia; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Male; Middle Aged; Phytosterols; Pilot Projects; Platelet Count; Treatment Outcome; United States; Young Adult | 2015 |
Ezetimibe ameliorates atherogenic lipids profiles, insulin resistance and hepatocyte growth factor in obese patients with hypercholesterolemia.
Topics: Atherosclerosis; Biomarkers; Drug Therapy, Combination; Ezetimibe; Female; Hepatocyte Growth Factor; Humans; Hypercholesterolemia; Insulin Resistance; Lipids; Male; Middle Aged; Obesity | 2015 |
ODYSSEY MONO: effect of alirocumab 75 mg subcutaneously every 2 weeks as monotherapy versus ezetimibe over 24 weeks.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Dose-Response Relationship, Drug; Drug Administration Schedule; Ezetimibe; Female; Humans; Hypercholesterolemia; Injections, Subcutaneous; Male; Middle Aged | 2015 |
[IMPROVE-IT Study proves effectiveness of ezetimib. The Higgs particle of lipidologists].
Topics: Acute Coronary Syndrome; Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Follow-Up Studies; Heptanoic Acids; Humans; Hypercholesterolemia; Pravastatin; Pyrroles; Simvastatin | 2014 |
Efficacy and safety of alirocumab in high cardiovascular risk patients with inadequately controlled hypercholesterolaemia on maximally tolerated doses of statins: the ODYSSEY COMBO II randomized controlled trial.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Cardiovascular Diseases; Cholesterol, LDL; Double-Blind Method; Drug Administration Schedule; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Injections, Subcutaneous; Male; Maximum Tolerated Dose; Middle Aged; Treatment Outcome | 2015 |
Efficacy and safety of ezetimibe monotherapy in children with heterozygous familial or nonfamilial hypercholesterolemia.
Topics: Anticholesteremic Agents; Azetidines; Child; Double-Blind Method; Ezetimibe; Female; Heterozygote; Humans; Hypercholesterolemia; Male; Single-Blind Method; Treatment Outcome | 2015 |
Modulation of adhesion molecules by cholesterol-lowering therapy in mononuclear cells from hypercholesterolemic patients.
Topics: Aged; Atorvastatin; Biomarkers; Cell Adhesion Molecules; Cell Line; Cholesterol, HDL; Cholesterol, LDL; Dose-Response Relationship, Drug; Ezetimibe; Ezetimibe, Simvastatin Drug Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Leukocytes, Mononuclear; Male; Middle Aged; RNA, Messenger; Simvastatin; Treatment Outcome | 2015 |
A randomized, double-blind, placebo-controlled study of the effect of ezetimibe on glucose metabolism in subjects with type 2 diabetes mellitus and hypercholesterolemia.
Topics: Anticholesteremic Agents; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Ezetimibe; Female; Glycated Hemoglobin; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Hypercholesterolemia; Male; Middle Aged; Serum Albumin; Triglycerides | 2015 |
Patient and physician factors influence decision-making in hypercholesterolemia: a questionnaire-based survey.
Topics: Aged; Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Patient Care Planning; Practice Patterns, Physicians'; Rosuvastatin Calcium; Surveys and Questionnaires | 2015 |
[Even lower values are even better!].
Topics: Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Myocardial Infarction; Risk Factors; Simvastatin; Stroke | 2015 |
[What is the use of even lower LDL cholesterol by combination therapy? A critical viewpoint].
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Comorbidity; Drug Therapy, Combination; Evidence-Based Medicine; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Prevalence; Risk Factors; Stroke; Survival Rate; Treatment Outcome | 2015 |
Influence of metabolic syndrome factors and insulin resistance on the efficacy of ezetimibe/simvastatin and atorvastatin in patients with metabolic syndrome and atherosclerotic coronary heart disease risk.
Topics: Aged; Anticholesteremic Agents; Atorvastatin; Blood Glucose; Blood Pressure; C-Reactive Protein; Cholesterol, LDL; Coronary Artery Disease; Coronary Disease; Double-Blind Method; Ezetimibe; Female; Humans; Hypercholesterolemia; Insulin Resistance; Lipoproteins, HDL; Male; Metabolic Syndrome; Middle Aged; Obesity, Abdominal; Risk Factors; Simvastatin; Treatment Outcome; Triglycerides | 2015 |
Efficacy and safety of adding alirocumab to rosuvastatin versus adding ezetimibe or doubling the rosuvastatin dose in high cardiovascular-risk patients: The ODYSSEY OPTIONS II randomized trial.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Cardiovascular Diseases; Cholesterol, LDL; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Injections, Subcutaneous; Retrospective Studies; Rosuvastatin Calcium; Time Factors; Treatment Outcome | 2016 |
Effects of simvastatin, ezetimibe and simvastatin/ezetimibe on mitochondrial function and leukocyte/endothelial cell interactions in patients with hypercholesterolemia.
Topics: Aged; Anticholesteremic Agents; Biomarkers; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Cholesterol; Coculture Techniques; Endothelial Cells; Ezetimibe; Ezetimibe, Simvastatin Drug Combination; Female; Humans; Hypercholesterolemia; Leukocytes; Male; Membrane Potential, Mitochondrial; Middle Aged; Mitochondria; Oxidative Stress; Simvastatin; Spain; Time Factors; Treatment Outcome | 2016 |
Clinical Profile of Statin Intolerance in the Phase 3 GAUSS-2 Study.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Cholesterol, LDL; Double-Blind Method; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Muscular Diseases; PCSK9 Inhibitors; Young Adult | 2016 |
Comparison of PCSK9 Inhibitor Evolocumab vs Ezetimibe in Statin-Intolerant Patients: Design of the Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin-Intolerant Subjects 3 (GAUSS-3) Trial.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Apolipoprotein B-100; Biomarkers; Cholesterol, LDL; Clinical Protocols; Double-Blind Method; Ezetimibe; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Muscular Diseases; PCSK9 Inhibitors; Proprotein Convertase 9; Research Design; Time Factors; Treatment Outcome | 2016 |
Efficacy and Tolerability of Evolocumab vs Ezetimibe in Patients With Muscle-Related Statin Intolerance: The GAUSS-3 Randomized Clinical Trial.
Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Atorvastatin; Biomarkers; Cholesterol, LDL; Creatine Kinase; Cross-Over Studies; Double-Blind Method; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Muscular Diseases; Myalgia; Myositis; Rhabdomyolysis; Time Factors | 2016 |
[Approval extension for statin plus ezetimib].
Topics: Acute Coronary Syndrome; Drug Approval; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Simvastatin | 2016 |
Efficacy and Safety of the PCSK9 Inhibitor Evolocumab in Patients with Mixed Hyperlipidemia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Apolipoproteins B; Cholesterol; Double-Blind Method; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Middle Aged; PCSK9 Inhibitors; Treatment Outcome; Triglycerides; Young Adult | 2016 |
Relationship Between Low-Density Lipoprotein Cholesterol, Free Proprotein Convertase Subtilisin/Kexin Type 9, and Alirocumab Levels After Different Lipid-Lowering Strategies.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Fenofibrate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Male; Middle Aged; Proprotein Convertase 9; Young Adult | 2016 |
Effect of fixed-dose combinations of ezetimibe plus rosuvastatin in patients with primary hypercholesterolemia: MRS-ROZE (Multicenter Randomized Study of ROsuvastatin and eZEtimibe).
Topics: Aged; Anticholesteremic Agents; Biomarkers; Cholesterol, LDL; Diabetes Mellitus; Double-Blind Method; Drug Combinations; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Metabolic Syndrome; Middle Aged; Republic of Korea; Rosuvastatin Calcium; Time Factors; Treatment Outcome; Triglycerides | 2016 |
Efficacy and Safety of Alirocumab 150 mg Every 4 Weeks in Patients With Hypercholesterolemia Not on Statin Therapy: The ODYSSEY CHOICE II Study.
Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Cholesterol, LDL; Combined Modality Therapy; Diet Therapy; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Fenofibrate; Humans; Hypercholesterolemia; Hypolipidemic Agents; Injection Site Reaction; Male; Middle Aged; PCSK9 Inhibitors; Treatment Outcome | 2016 |
Effect of Alirocumab on Lipoprotein(a) Over ≥1.5 Years (from the Phase 3 ODYSSEY Program).
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Double-Blind Method; Drug Therapy, Combination; Endpoint Determination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoprotein(a); Male; Middle Aged; Treatment Outcome | 2017 |
Population Pharmacokinetics (PK) and Pharmacodynamics (PD) Analysis of LY3015014, a Monoclonal Antibody to Protein Convertase Subtilisin/Kexin Type 9 (PCSK9) in Healthy Subjects and Hypercholesterolemia Patients.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Anticholesteremic Agents; Ezetimibe; Female; Healthy Volunteers; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Immunoglobulin G; Male; Middle Aged; Proprotein Convertase 9; Young Adult | 2017 |
Lipid-Modifying Efficacy and Tolerability of Anacetrapib Added to Ongoing Statin Therapy in Patients with Hypercholesterolemia or Low High-Density Lipoprotein Cholesterol.
Topics: Aged; Anticholesteremic Agents; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Dyslipidemias; Ezetimibe; Female; Fibric Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Niacin; Oxazolidinones; Treatment Outcome | 2017 |
Combination Therapy of Rosuvastatin and Ezetimibe in Patients with High Cardiovascular Risk.
Topics: Aged; Anticholesteremic Agents; Cardiovascular Diseases; Cholesterol; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Risk Factors; Rosuvastatin Calcium; Treatment Outcome; Triglycerides | 2017 |
Effect of two lipid-lowering strategies on high-density lipoprotein function and some HDL-related proteins: a randomized clinical trial.
Topics: Anticholesteremic Agents; Apolipoproteins; Atorvastatin; Cholesterol, HDL; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Treatment Outcome; Vascular Cell Adhesion Molecule-1 | 2017 |
The effect of orlistat and ezetimibe, alone or in combination, on serum LDL and small dense LDL cholesterol levels in overweight and obese patients with hypercholesterolaemia.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Aged; Anti-Obesity Agents; Anticholesteremic Agents; Azetidines; Body Mass Index; Caloric Restriction; Cholesterol, LDL; Diet, Fat-Restricted; Drug Therapy, Combination; Ezetimibe; Female; gamma-Glutamyltransferase; Homeostasis; Humans; Hypercholesterolemia; Lactones; Male; Middle Aged; Obesity; Orlistat; Overweight; Treatment Outcome; Uric Acid | 2008 |
Safety and efficacy of ezetimibe monotherapy in 1624 primary hypercholesterolaemic patients for up to 2 years.
Topics: Adult; Aged; Anticholesteremic Agents; Azetidines; Double-Blind Method; Ezetimibe; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Male; Middle Aged | 2008 |
The effects of low-dose simvastatin and ezetimibe compared to high-dose simvastatin alone on post-fat load endothelial function in patients with metabolic syndrome: a randomized double-blind crossover trial.
Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Cross-Over Studies; Dietary Fats; Double-Blind Method; Drug Therapy, Combination; Endothelium, Vascular; Ezetimibe; Humans; Hypercholesterolemia; Male; Metabolic Syndrome; Middle Aged; Postprandial Period; Prospective Studies; Simvastatin; Triglycerides | 2008 |
Sustained effects in hypercholesterolaemic patients on combined simvastatin/ezetimibe treatment: observational cohort study in clinical practice.
Topics: Administration, Oral; Aged; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Cohort Studies; Drug Therapy, Combination; Ezetimibe; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Male; Middle Aged; Professional Practice; Prospective Studies; Risk Factors; Simvastatin; Time Factors; Triglycerides | 2008 |
Ezetimibe alone reduces low-density lipoprotein cholesterol in HIV-infected patients receiving combination antiretroviral therapy.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Azetidines; Cholesterol, LDL; Ezetimibe; Female; HIV Infections; Humans; Hypercholesterolemia; Male; Middle Aged; Placebos | 2008 |
Long-term (48-week) safety of ezetimibe 10 mg/day coadministered with simvastatin compared to simvastatin alone in patients with primary hypercholesterolemia.
Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Azetidines; Ezetimibe; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Male; Middle Aged; Simvastatin; Time Factors | 2008 |
Long-term efficacy and safety of ezetimibe 10 mg in patients with homozygous sitosterolemia: a 2-year, open-label extension study.
Topics: Achilles Tendon; Adolescent; Adult; Aged; Anticholesteremic Agents; Azetidines; Child; Double-Blind Method; Ezetimibe; Female; Homozygote; Humans; Hypercholesterolemia; Male; Middle Aged; Sitosterols; Treatment Outcome; Young Adult | 2008 |
Ezetimibe 5 and 10 mg for lowering LDL-C: potential billion-dollar savings with improved tolerability.
Topics: Aged; Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol, LDL; Dose-Response Relationship, Drug; Ezetimibe; Female; Heptanoic Acids; Hospitals, Veterans; Humans; Hypercholesterolemia; Male; Pyrroles | 2008 |
Long-term safety and tolerability of ezetimibe coadministered with simvastatin in hypercholesterolemic patients: a randomized, 12-month double-blind extension study.
Topics: Adult; Aged; Aged, 80 and over; Algorithms; Anticholesteremic Agents; Azetidines; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Placebos; Simvastatin; Time Factors; Treatment Outcome | 2008 |
Use of ezetimibe during HIV infection.
Topics: Anticholesteremic Agents; Azetidines; Ezetimibe; HIV Infections; Humans; Hypercholesterolemia; Treatment Outcome | 2009 |
Efficacy and safety of ezetimibe added on to atorvastatin (20 mg) versus uptitration of atorvastatin (to 40 mg) in hypercholesterolemic patients at moderately high risk for coronary heart disease.
Topics: Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol, LDL; Coronary Artery Disease; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Ezetimibe; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Logistic Models; Male; Middle Aged; Pyrroles; Risk Assessment; Risk Factors; Treatment Outcome | 2008 |
Efficacy and safety of ezetimibe added on to atorvastatin (40 mg) compared with uptitration of atorvastatin (to 80 mg) in hypercholesterolemic patients at high risk of coronary heart disease.
Topics: Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol, LDL; Coronary Artery Disease; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Ezetimibe; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Pyrroles; Risk Assessment; Treatment Outcome | 2008 |
Tolerability and effects on lipids of ezetimibe coadministered with pravastatin or simvastatin for twelve months: results from two open-label extension studies in hypercholesterolemic patients.
Topics: Adult; Aged; Anticholesteremic Agents; Arthralgia; Azetidines; Body Mass Index; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Female; Follow-Up Studies; Headache; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Patient Dropouts; Pravastatin; Respiratory Tract Infections; Simvastatin; Sinusitis; Treatment Outcome; Triglycerides | 2008 |
Lipid-altering efficacy of ezetimibe/simvastatin 10/20 mg compared with rosuvastatin 10 mg in high-risk hypercholesterolaemic patients inadequately controlled with prior statin monotherapy - The IN-CROSS study.
Topics: Adult; Aged; Aged, 80 and over; Azetidines; Cholesterol, LDL; Coronary Artery Disease; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pyrimidines; Risk Factors; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Treatment Outcome | 2009 |
Changes in cholesterol absorption and cholesterol synthesis caused by ezetimibe and/or simvastatin in men.
Topics: Adult; Anticholesteremic Agents; Azetidines; Cholesterol; Double-Blind Method; Drug Combinations; Ezetimibe; Humans; Hypercholesterolemia; Male; Middle Aged; Simvastatin; Young Adult | 2009 |
Effect of ezetimibe/simvastatin compared with atorvastatin on lipoprotein subclasses in patients with type 2 diabetes and hypercholesterolaemia.
Topics: Adult; Aged; Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Ezetimibe; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Pyrroles; Simvastatin; Young Adult | 2009 |
Lipid-altering efficacy and safety of ezetimibe/simvastatin versus atorvastatin in patients with hypercholesterolemia and the metabolic syndrome (from the VYMET study).
Topics: Adolescent; Aged; Anticholesteremic Agents; Atorvastatin; Azetidines; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hypercholesterolemia; Lipids; Male; Metabolic Syndrome; Middle Aged; Pyrroles; Simvastatin; Treatment Outcome; Young Adult | 2009 |
Ezetimibe as monotherapy in the treatment of hypercholesterolemia in children and adolescents.
Topics: Adolescent; Anticholesteremic Agents; Azetidines; Child; Cholesterol, HDL; Cholesterol, LDL; Ezetimibe; Female; Humans; Hypercholesterolemia; Hyperlipidemia, Familial Combined; Male; Prospective Studies; Treatment Outcome; Triglycerides | 2009 |
Short-term ezetimibe is well tolerated and effective in combination with statin therapy to treat elevated LDL cholesterol in HIV-infected patients.
Topics: Anticholesteremic Agents; Antiretroviral Therapy, Highly Active; Azetidines; CD4 Lymphocyte Count; Cholesterol, LDL; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Ezetimibe; Female; HIV Infections; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged | 2009 |
Pleiotropic effects with equivalent low-density lipoprotein cholesterol reduction: comparative study between simvastatin and simvastatin/ezetimibe coadministration.
Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Azetidines; Brachial Artery; C-Reactive Protein; Cholesterol, LDL; Cross-Over Studies; Drug Therapy, Combination; Endothelium, Vascular; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Simvastatin; Ultrasonography; Vasodilation; Young Adult | 2010 |
Rosuvastatin increased serum osteocalcin levels independent of its serum cholesterol-lowering effect in patients with type 2 diabetes and hypercholesterolemia.
Topics: Aged; Alkaline Phosphatase; Amino Acids; Azetidines; Bone and Bones; Cholesterol; Cholesterol, LDL; Collagen Type I; Diabetes Mellitus, Type 2; Ezetimibe; Female; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Osteocalcin; Peptides; Pyrimidines; Rosuvastatin Calcium; Sulfonamides | 2009 |
Safety and efficacy of combined ezetimibe/simvastatin treatment and simvastatin monotherapy in patients with non-alcoholic fatty liver disease.
Topics: Aged; Alanine Transaminase; Anticholesteremic Agents; Aspartate Aminotransferases; Azetidines; Cardiovascular Diseases; Cholesterol; Creatine Kinase; Drug Combinations; Ezetimibe; Ezetimibe, Simvastatin Drug Combination; Fatty Liver; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Male; Metabolic Syndrome; Middle Aged; Retrospective Studies; Risk Factors; Simvastatin; Triglycerides | 2009 |
Ezetimibe effect on bone mineral density and markers of bone formation and resorption.
Topics: Alkaline Phosphatase; Anticholesteremic Agents; Azetidines; Biomarkers; Bone Density; Bone Remodeling; Collagen Type I; Ezetimibe; Female; Humans; Hypercholesterolemia; Lipids; Male; Peptide Fragments | 2010 |
Ezetimibe added to atorvastatin compared with doubling the atorvastatin dose in patients at high risk for coronary heart disease with diabetes mellitus, metabolic syndrome or neither.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Atorvastatin; Azetidines; Canada; Coronary Artery Disease; Diabetic Angiopathies; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Ezetimibe; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Metabolic Syndrome; Middle Aged; Pyrroles; Risk Factors; Treatment Outcome; United States; Young Adult | 2010 |
Incremental cholesterol reduction with ezetimibe/simvastatin, atorvastatin and rosuvastatin in UK General Practice (IN-PRACTICE): randomised controlled trial of achievement of Joint British Societies (JBS-2) cholesterol targets.
Topics: Aged; Analysis of Variance; Anticholesteremic Agents; Atorvastatin; Azetidines; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Fluorobenzenes; General Practice; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Prospective Studies; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Secondary Prevention; Simvastatin; Sulfonamides; Treatment Outcome | 2010 |
Lipid-altering efficacy of ezetimibe/simvastatin 10/20 mg compared to rosuvastatin 10 mg in high-risk patients with and without type 2 diabetes mellitus inadequately controlled despite prior statin monotherapy.
Topics: Anticholesteremic Agents; Apolipoproteins B; Azetidines; C-Reactive Protein; Cholesterol; Cholesterol, LDL; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Ezetimibe; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Odds Ratio; Pyrimidines; Rosuvastatin Calcium; Simvastatin; Sulfonamides | 2012 |
Lipid-lowering effects of ezetimibe for hypercholesterolemic patients with and without type 2 diabetes mellitus.
Topics: Aged; Azetidines; Biomarkers; Body Mass Index; C-Reactive Protein; Cardiovascular Diseases; Cholestanol; Cholesterol; Cholesterol, LDL; Diabetes Mellitus, Type 2; Ezetimibe; Female; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lipids; Male; Middle Aged; Phytosterols; Sitosterols | 2010 |
Influence of age, gender, and race on the efficacy of adding ezetimibe to atorvastatin vs. atorvastatin up-titration in patients at moderately high or high risk for coronary heart disease.
Topics: Adolescent; Adult; Age Factors; Aged; Atorvastatin; Azetidines; Coronary Disease; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Pyrroles; Racial Groups; Risk Factors; Sex Factors; Treatment Outcome; Young Adult | 2011 |
Safety and efficacy of ezetimibe/simvastatin combination versus atorvastatin alone in adults ≥65 years of age with hypercholesterolemia and with or at moderately high/high risk for coronary heart disease (the VYTELD study).
Topics: Aged; Anticholesteremic Agents; Atorvastatin; Azetidines; Biomarkers; Coronary Disease; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Lipids; Logistic Models; Male; Pyrroles; Risk Factors; Simvastatin; Treatment Outcome | 2010 |
Ezetimibe/simvastatin 10/20 mg versus rosuvastatin 10 mg in high-risk hypercholesterolemic patients stratified by prior statin treatment potency.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Azetidines; Ezetimibe; Female; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pyrimidines; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Treatment Outcome; Young Adult | 2010 |
The effect of simvastatin alone versus simvastatin plus ezetimibe on the concentration of small dense low-density lipoprotein cholesterol in subjects with primary hypercholesterolemia.
Topics: Aged; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Drug Combinations; Ezetimibe; Female; Follow-Up Studies; Greece; Humans; Hypercholesterolemia; Male; Middle Aged; Osmolar Concentration; Particle Size; Simvastatin | 2011 |
The effect of ezetimibe and simvastatin on monocyte cytokine release in patients with isolated hypercholesterolemia.
Topics: Anticholesteremic Agents; Azetidines; Cytokines; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Monocytes; Risk Factors; Simvastatin; Time Factors | 2011 |
The effects of statin monotherapy and low-dose statin/ezetimibe on lipoprotein-associated phospholipase A₂.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Adult; Aged; Anticholesteremic Agents; Atorvastatin; Azetidines; Biomarkers, Pharmacological; Chemokine CCL2; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Female; Fibrinogen; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Interleukin-6; Male; Middle Aged; Pyrroles; Treatment Outcome; Young Adult | 2011 |
Pleiotropic effects of ezetimibe/simvastatin vs. high dose simvastatin.
Topics: Aged; Anticholesteremic Agents; Apolipoproteins B; Azetidines; Biomarkers; Cholesterol, LDL; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Synergism; Ezetimibe; Female; Humans; Hypercholesterolemia; Lipoproteins, LDL; Male; Middle Aged; Platelet Aggregation; Simvastatin | 2012 |
Switching from statin monotherapy to ezetimibe/simvastatin or rosuvastatin modifies the relationships between apolipoprotein B, LDL cholesterol, and non-HDL cholesterol in patients at high risk of coronary disease.
Topics: Aged; Apolipoproteins B; Azetidines; Cholesterol; Coronary Disease; Ezetimibe; Female; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pyrimidines; Rosuvastatin Calcium; Simvastatin; Sulfonamides | 2011 |
Ezetimibe treatment lowers indicators of oxidative stress in hypercholesterolemic subjects with high oxidative stress.
Topics: Aged; Anticholesteremic Agents; Azetidines; Biomarkers; Dinoprost; Ezetimibe; Humans; Hypercholesterolemia; Lipoproteins, LDL; Male; Middle Aged; Oxidative Stress | 2011 |
Efficacy of ezetimibe as monotherapy or combination therapy in hypercholesterolemic patients with and without diabetes.
Topics: Adult; Aged; Anticholesteremic Agents; Azetidines; Blood Glucose; Cholesterol; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Ezetimibe; Female; Fenofibrate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Male; Middle Aged | 2011 |
The effect of ezetimibe and simvastatin on hemostasis in patients with isolated hypercholesterolemia.
Topics: Adult; Aged; Azetidines; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Hemostasis; Humans; Hypercholesterolemia; Male; Middle Aged; Simvastatin; Treatment Outcome; Young Adult | 2012 |
Safety and efficacy of ezetimibe added on to rosuvastatin 5 or 10 mg versus up-titration of rosuvastatin in patients with hypercholesterolemia (the ACTE Study).
Topics: Aged; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pyrimidines; Rosuvastatin Calcium; Sulfonamides; Treatment Outcome | 2011 |
The effect of ezetimibe, administered alone or in combination with simvastatin, on lymphocyte cytokine release in patients with elevated cholesterol levels.
Topics: Anticholesteremic Agents; Azetidines; Cytokines; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hypercholesterolemia; Inflammation; Lymphocytes; Male; Middle Aged; Prospective Studies; Simvastatin | 2012 |
Begin with the real-world patients of non-goal-achieved hypercholesterolemia in taiwan through the ezetimibe/simvastatin tablet - The BRAVO Study.
Topics: Adult; Aged; Anticholesteremic Agents; Azetidines; Cholesterol, HDL; Cholesterol, LDL; Drug Combinations; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Simvastatin; Taiwan; Time Factors; Triglycerides | 2011 |
Combined effects of ezetimibe and phytosterols on cholesterol metabolism: a randomized, controlled feeding study in humans.
Topics: Adult; Aged; Anticholesteremic Agents; Azetidines; Cholesterol, Dietary; Cholesterol, LDL; Combined Modality Therapy; Drug Synergism; Ezetimibe; Female; Humans; Hypercholesterolemia; Lipid Metabolism; Male; Middle Aged; Phytosterols; Young Adult | 2011 |
The role of soluble fiber intake in patients under highly effective lipid-lowering therapy.
Topics: Azetidines; Blood Glucose; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dietary Fiber; Ezetimibe; Female; Fluorobenzenes; Humans; Hypercholesterolemia; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Male; Middle Aged; Phytosterols; Pyrimidines; Rosuvastatin Calcium; Sitosterols; Sulfonamides; Triglycerides | 2011 |
Comparison of the effects of simvastatin vs. rosuvastatin vs. simvastatin/ezetimibe on parameters of insulin resistance.
Topics: Aged; Azetidines; Blood Glucose; Body Mass Index; Cholesterol, LDL; Drug Combinations; Ezetimibe; Fasting; Female; Fluorobenzenes; Homeostasis; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Insulin Resistance; Male; Medication Adherence; Middle Aged; Pyrimidines; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Treatment Outcome | 2011 |
Influence of ezetimibe monotherapy on ischemia-modified albumin levels in hypercholesterolemic patients.
Topics: Aged; Anticholesteremic Agents; Atherosclerosis; Azetidines; Biomarkers; Cholesterol, LDL; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Oxidative Stress; Prospective Studies; Regression Analysis; Risk Factors; Serum Albumin; Serum Albumin, Human | 2011 |
Oxidative stress improvement is associated with increased levels of taurine in CKD patients undergoing lipid-lowering therapy.
Topics: Aged; Allantoin; Azetidines; Drug Administration Schedule; Drug Combinations; Ezetimibe; Female; Humans; Hypercholesterolemia; Hypolipidemic Agents; Kidney; Kidney Failure, Chronic; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Simvastatin; Sulfhydryl Compounds; Superoxides; Taurine; Uric Acid | 2012 |
Ezetimibe/simvastatin 10/40 mg versus atorvastatin 40 mg in high cardiovascular risk patients with primary hypercholesterolemia: a randomized, double-blind, active-controlled, multicenter study.
Topics: Aged; Anticholesteremic Agents; Atorvastatin; Azetidines; C-Reactive Protein; Cardiovascular Diseases; Double-Blind Method; Drug Combinations; Ezetimibe; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Lipids; Male; Middle Aged; Pyrroles; Simvastatin; Treatment Outcome | 2012 |
Impact of efavirenz on intestinal metabolism and transport: insights from an interaction study with ezetimibe in healthy volunteers.
Topics: Adult; Alkynes; Animals; Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azetidines; Benzoxazines; Biological Transport; Cell Line; Cell Line, Transformed; Cyclopropanes; Cytochrome P-450 CYP3A; Dogs; Drug Interactions; Ezetimibe; Gene Expression; Glucuronosyltransferase; HEK293 Cells; HIV Infections; Humans; Hypercholesterolemia; Intestinal Absorption; Intestinal Mucosa; Intestines; Liver; Liver-Specific Organic Anion Transporter 1; Male; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organic Anion Transporters; RNA, Messenger; Young Adult | 2012 |
Efficacy, safety and tolerability of ongoing statin plus ezetimibe versus doubling the ongoing statin dose in hypercholesterolemic Taiwanese patients: an open-label, randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Azetidines; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intention to Treat Analysis; Lipids; Male; Middle Aged; Taiwan; Treatment Outcome; Young Adult | 2012 |
Double-dose pravastatin versus add-on ezetimibe with low-dose pravastatin - effects on LDL cholesterol, cholesterol absorption, and cholesterol synthesis in Japanese patients with hypercholesterolemia (PEAS study).
Topics: Adult; Aged; Anticholesteremic Agents; Azetidines; Cholesterol; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Japan; Middle Aged; Patient Compliance; Pravastatin | 2012 |
Effect of treatment with pravastatin or ezetimibe on endothelial function in patients with moderate hypercholesterolemia.
Topics: Adult; Anticholesteremic Agents; Azetidines; Biomarkers; Brachial Artery; Cholesterol; Endothelium, Vascular; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Italy; Male; Middle Aged; Pravastatin; Severity of Illness Index; Treatment Outcome; Ultrasonography; Vasodilation | 2013 |
Differences in synthesis and absorption of cholesterol of two effective lipid-lowering therapies.
Topics: Adult; Aged; Anticholesteremic Agents; Azetidines; Biomarkers; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Female; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Prospective Studies; Pyrimidines; Rosuvastatin Calcium; Simvastatin; Sulfonamides | 2012 |
Nutraceutical pill containing berberine versus ezetimibe on plasma lipid pattern in hypercholesterolemic subjects and its additive effect in patients with familial hypercholesterolemia on stable cholesterol-lowering treatment.
Topics: Aged; Anticholesteremic Agents; Azetidines; Berberine; Biological Products; Cholesterol, LDL; Dietary Supplements; Drug Combinations; Drug Therapy, Combination; Ezetimibe; Fatty Alcohols; Female; Humans; Hypercholesterolemia; Lipids; Male; Middle Aged; Mutation; Receptors, LDL; Statistics, Nonparametric; Triglycerides | 2012 |
Effects of ezetimibe on visceral fat in the metabolic syndrome: a randomised controlled study.
Topics: Adiponectin; Aged; Anticholesteremic Agents; Azetidines; Ezetimibe; Female; Humans; Hypercholesterolemia; Intra-Abdominal Fat; Male; Metabolic Syndrome; Middle Aged; Tomography, X-Ray Computed | 2012 |
Effects of ezetimibe added to statin therapy on markers of cholesterol absorption and synthesis and LDL-C lowering in hyperlipidemic patients.
Topics: Aged; Anticholesteremic Agents; Apolipoproteins; Azetidines; Biomarkers; C-Reactive Protein; Cholesterol; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestinal Absorption; Male; Middle Aged; Multivariate Analysis; Sitosterols; Time Factors; Treatment Outcome; United States | 2012 |
Efficacy, safety, and tolerability of a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 in combination with a statin in patients with hypercholesterolaemia (LAPLACE-TIMI 57): a randomised, placebo-controlled, dose-ranging, phase 2 stu
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Azetidines; Cholesterol, HDL; Cholesterol, LDL; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Immunoglobulin G; Male; Middle Aged; Proprotein Convertase 9; Proprotein Convertases; Serine Endopeptidases; Treatment Outcome; Young Adult | 2012 |
Effects of adding ezetimibe to fluvastatin on kidney function in patients with hypercholesterolemia: a randomized control trial.
Topics: Adult; Anticholesteremic Agents; Azetidines; Drug Therapy, Combination; Ezetimibe; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hypercholesterolemia; Indoles; Kidney Function Tests; Male; Middle Aged | 2013 |
Inhibition of intestinal cholesterol absorption by ezetimibe in humans.
Topics: Adult; Anticholesteremic Agents; Azetidines; Cholesterol; Cross-Over Studies; Double-Blind Method; Ezetimibe; Humans; Hypercholesterolemia; Intestinal Absorption; Lipoproteins; Male; Middle Aged; Sterols | 2002 |
Efficacy and safety of ezetimibe added to ongoing statin therapy for treatment of patients with primary hypercholesterolemia.
Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Azetidines; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Prospective Studies; Quebec; Treatment Outcome; Triglycerides; United States | 2002 |
Efficacy and safety of a potent new selective cholesterol absorption inhibitor, ezetimibe, in patients with primary hypercholesterolemia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Apolipoproteins B; Azetidines; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Ezetimibe; Female; Humans; Hypercholesterolemia; Lipoproteins, HDL; Lipoproteins, HDL3; Male; Middle Aged; Treatment Outcome; Triglycerides; United States | 2002 |
Ezetimibe coadministered with simvastatin in patients with primary hypercholesterolemia.
Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Azetidines; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hypercholesterolemia; Lipids; Male; Middle Aged; Simvastatin; Treatment Outcome | 2002 |
Efficacy and safety of ezetimibe coadministered with lovastatin in primary hypercholesterolemia.
Topics: Aged; Anticholesteremic Agents; Apolipoprotein A-I; Apolipoproteins B; Azetidines; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hypercholesterolemia; Lipoprotein(a); Lovastatin; Male; Middle Aged; Practice Guidelines as Topic; Safety; Treatment Outcome; Triglycerides | 2003 |
Efficacy and safety of ezetimibe coadministered with pravastatin in patients with primary hypercholesterolemia: a prospective, randomized, double-blind trial.
Topics: Adult; Aged; Anticholesteremic Agents; Azetidines; Double-Blind Method; Ezetimibe; Female; Humans; Hypercholesterolemia; Lipids; Male; Middle Aged; Pravastatin; Treatment Outcome; Vitamins | 2003 |
Effects of ezetimibe, a new cholesterol absorption inhibitor, on plasma lipids in patients with primary hypercholesterolemia.
Topics: Adult; Aged; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Cosyntropin; Double-Blind Method; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Single-Blind Method; Triglycerides; Vitamins | 2003 |
Effect of ezetimibe coadministered with atorvastatin in 628 patients with primary hypercholesterolemia: a prospective, randomized, double-blind trial.
Topics: Anticholesteremic Agents; Atorvastatin; Azetidines; C-Reactive Protein; Cholesterol, HDL; Cholesterol, LDL; Digestive System; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Ezetimibe; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Musculoskeletal Diseases; Prospective Studies; Pyrroles; Treatment Outcome; Triglycerides | 2003 |
Evaluation of the efficacy, safety, and tolerability of ezetimibe in primary hypercholesterolaemia: a pooled analysis from two controlled phase III clinical studies.
Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Diet Records; Double-Blind Method; Ezetimibe; Female; Humans; Hypercholesterolemia; Liver Function Tests; Male; Middle Aged; Patient Satisfaction; Single-Blind Method | 2003 |
Effect of coadministration of ezetimibe and simvastatin on high-sensitivity C-reactive protein.
Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Apolipoproteins B; Azetidines; C-Reactive Protein; Cholesterol, HDL; Cholesterol, LDL; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Simvastatin; Treatment Outcome; Triglycerides | 2003 |
Efficacy and safety of ezetimibe coadministered with simvastatin in patients with primary hypercholesterolemia: a randomized, double-blind, placebo-controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Simvastatin; Treatment Outcome | 2004 |
Treatment of high-risk patients with ezetimibe plus simvastatin co-administration versus simvastatin alone to attain National Cholesterol Education Program Adult Treatment Panel III low-density lipoprotein cholesterol goals.
Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Coronary Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Practice Guidelines as Topic; Risk Factors; Simvastatin; Treatment Outcome | 2004 |
Efficacy and safety of ezetimibe co-administered with simvastatin compared with atorvastatin in adults with hypercholesterolemia.
Topics: Anticholesteremic Agents; Apolipoproteins; Atorvastatin; Azetidines; Cholesterol; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Pyrroles; Simvastatin; Treatment Outcome | 2004 |
Long-term safety and tolerability profile of ezetimibe and atorvastatin coadministration therapy in patients with primary hypercholesterolaemia.
Topics: Adult; Aged; Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Pyrroles; Treatment Outcome | 2004 |
Pharmacodynamic interaction between ezetimibe and rosuvastatin.
Topics: Adult; Anticholesteremic Agents; Azetidines; Drug Synergism; Drug Therapy, Combination; Ezetimibe; Female; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pilot Projects; Pyrimidines; Rosuvastatin Calcium; Single-Blind Method; Sulfonamides; Treatment Outcome | 2004 |
Pharmacodynamic and pharmacokinetic interaction between fenofibrate and ezetimibe.
Topics: Adult; Azetidines; Drug Interactions; Drug Therapy, Combination; Ezetimibe; Female; Fenofibrate; Humans; Hypercholesterolemia; Hypolipidemic Agents; Male; Middle Aged; Pilot Projects; Single-Blind Method; Treatment Outcome | 2004 |
Efficacy and safety of ezetimibe coadministered with statins: randomised, placebo-controlled, blinded experience in 2382 patients with primary hypercholesterolemia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Azetidines; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Treatment Outcome | 2004 |
Effects of ezetimibe added to on-going statin therapy on the lipid profile of hypercholesterolemic patients with diabetes mellitus or metabolic syndrome.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Diabetes Complications; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Male; Metabolic Syndrome; Middle Aged | 2004 |
Achieving lipoprotein goals in patients at high risk with severe hypercholesterolemia: efficacy and safety of ezetimibe co-administered with atorvastatin.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Pyrroles; Risk Factors; Triglycerides | 2004 |
Efficacy and safety of coadministration of ezetimibe and statins in elderly patients with primary hypercholesterolaemia.
Topics: Adult; Aged; Aged, 80 and over; Aging; Alanine Transaminase; Anticholesteremic Agents; Aspartate Aminotransferases; Azetidines; Cholesterol, LDL; Cross-Over Studies; Double-Blind Method; Drug Interactions; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Middle Aged | 2004 |
A multicenter, randomized, double-blind, placebo-controlled, factorial design study to evaluate the lipid-altering efficacy and safety profile of the ezetimibe/simvastatin tablet compared with ezetimibe and simvastatin monotherapy in patients with primary
Topics: Administration, Oral; Alanine Transaminase; Anticholesteremic Agents; Aspartate Aminotransferases; Azetidines; Cholesterol, LDL; Data Interpretation, Statistical; Double-Blind Method; Drug Combinations; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Simvastatin; Tablets; Triglycerides | 2004 |
Effects of ezetimibe coadministered with simvastatin on C-reactive protein in a large cohort of hypercholesterolemic patients.
Topics: Aged; Anticholesteremic Agents; Azetidines; C-Reactive Protein; Cholesterol, LDL; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Prospective Studies; Simvastatin | 2005 |
Long-term safety and, tolerability profiles and lipid-modifying efficacy of ezetimibe coadministered with ongoing simvastatin treatment: a multicenter, randomized, double-blind, placebo-controlled, 48-week extension study.
Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Azetidines; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hypercholesterolemia; Lipoproteins; Male; Middle Aged; Simvastatin; Time Factors | 2005 |
Effects of ezetimibe on plasma lipoproteins in severely hypercholesterolemic patients treated with regular LDL-apheresis and statins.
Topics: Aged; Anticholesteremic Agents; Atorvastatin; Azetidines; Blood Component Removal; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Combined Modality Therapy; Cross-Over Studies; Drug Therapy, Combination; Ezetimibe; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoproteins; Male; Middle Aged; Pyrroles; Simvastatin; Triglycerides | 2005 |
Treatment of hypercholesterolemia with ezetimibe in the kidney transplant population.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Ezetimibe; Female; Humans; Hypercholesterolemia; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Postoperative Complications | 2005 |
Dose-comparison study of the combination of ezetimibe and simvastatin (Vytorin) versus atorvastatin in patients with hypercholesterolemia: the Vytorin Versus Atorvastatin (VYVA) study.
Topics: Adult; Aged; Anticholesteremic Agents; Azetidines; C-Reactive Protein; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Simvastatin | 2005 |
A community-based, randomized trial of ezetimibe added to statin therapy to attain NCEP ATP III goals for LDL cholesterol in hypercholesterolemic patients: the ezetimibe add-on to statin for effectiveness (EASE) trial.
Topics: Aged; Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol, LDL; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Fatty Acids, Monounsaturated; Female; Fluvastatin; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Male; Middle Aged; Nephelometry and Turbidimetry; Practice Guidelines as Topic; Pravastatin; Pyrroles; Retrospective Studies; Risk Factors; Simvastatin | 2005 |
LDL-C goal attainment with the addition of ezetimibe to ongoing simvastatin treatment in coronary heart disease patients with hypercholesterolemia.
Topics: Administration, Oral; Aged; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Coronary Disease; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Placebos; Simvastatin; Treatment Outcome | 2005 |
Efficacy and safety of ezetimibe co-administered with ongoing atorvastatin therapy in achieving low-density lipoprotein goal in patients with hypercholesterolemia and coronary heart disease.
Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol, LDL; Coronary Disease; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Pyrroles; Safety | 2005 |
Effect of co-administering ezetimibe with on-going simvastatin treatment on LDL-C goal attainment in hypercholesterolemic patients with coronary heart disease.
Topics: Anticholesteremic Agents; Apolipoproteins B; Azetidines; Cholesterol, LDL; Coronary Disease; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hypercholesterolemia; International Cooperation; Male; Middle Aged; Prospective Studies; Safety; Simvastatin; Treatment Outcome; Triglycerides | 2005 |
The effect of fluvastatin on the pharmacokinetics and pharmacodynamics of ezetimibe.
Topics: Adult; Anticholesteremic Agents; Azetidines; Cholesterol, HDL; Cholesterol, LDL; Drug Synergism; Drug Therapy, Combination; Ezetimibe; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hypercholesterolemia; Indoles; Male; Middle Aged | 2005 |
Lipid-altering efficacy of switching from atorvastatin 10 mg/day to ezetimibe/simvastatin 10/20 mg/day compared to doubling the dose of atorvastatin in hypercholesterolaemic patients with atherosclerosis or coronary heart disease.
Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Apolipoproteins B; Atherosclerosis; Atorvastatin; Azetidines; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Double-Blind Method; Drug Therapy, Combination; Europe; Ezetimibe; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Pyrroles; Simvastatin; Taiwan; Treatment Outcome | 2005 |
Ezetimibe for the treatment of uncontrolled hypercholesterolemia in patients with high-dose statin therapy after renal transplantation.
Topics: Adult; Aged; Anticholesteremic Agents; Azetidines; Cholesterol; Cyclosporine; Drug Therapy, Combination; Ezetimibe; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Kidney Transplantation; Liver; Male; Middle Aged; Muscle, Skeletal; Pravastatin; Simvastatin; Tacrolimus | 2006 |
Effect of ezetimibe on low-density lipoprotein subtype distribution: results of a placebo-controlled, double-blind trial in patients treated by regular low-density lipoprotein apheresis and statins.
Topics: Anticholesteremic Agents; Azetidines; Blood Component Removal; Cholesterol, HDL; Cholesterol, LDL; Combined Modality Therapy; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Triglycerides | 2006 |
Efficacy and safety of coadministration of ezetimibe and simvastatin in African-American patients with primary hypercholesterolemia.
Topics: Adult; Aged; Anticholesteremic Agents; Azetidines; Black or African American; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Safety; Simvastatin; Treatment Outcome | 2006 |
Efficacy, safety and LDL-C goal attainment of ezetimibe 10 mg-simvastatin 20 mg vs. placebo-simvastatin 20 mg in UK-based adults with coronary heart disease and hypercholesterolaemia.
Topics: Adult; Aged; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Coronary Disease; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Simvastatin; Treatment Outcome | 2006 |
Effectiveness of ezetimibe added to ongoing statin therapy in modifying lipid profiles and low-density lipoprotein cholesterol goal attainment in patients of different races and ethnicities: a substudy of the Ezetimibe add-on to statin for effectiveness t
Topics: Anticholesteremic Agents; Azetidines; Black or African American; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Hispanic or Latino; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; United States; White People | 2006 |
Efficacy and tolerability of ezetimibe 10 mg/day coadministered with statins in patients with primary hypercholesterolemia who do not achieve target LDL-C while on statin monotherapy: A Canadian, multicentre, prospective study--the Ezetrol Add-On Study.
Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Azetidines; Canada; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Prospective Studies; Safety; Treatment Outcome | 2006 |
Lipid-lowering effects of colesevelam HCl in combination with ezetimibe.
Topics: Adult; Aged; Aged, 80 and over; Allylamine; Apolipoprotein A-I; Apolipoproteins B; Azetidines; Cholesterol; Colesevelam Hydrochloride; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hypercholesterolemia; Hypolipidemic Agents; Male; Middle Aged; Patient Compliance; Treatment Outcome | 2006 |
Lipoprotein effects of combined ezetimibe and colesevelam hydrochloride versus ezetimibe alone in hypercholesterolemic subjects: a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Allylamine; Anticholesteremic Agents; Azetidines; Cholesterol, HDL; Cholesterol, LDL; Colesevelam Hydrochloride; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Pilot Projects; Triglycerides | 2006 |
Ezetimibe/simvastatin vs atorvastatin in patients with type 2 diabetes mellitus and hypercholesterolemia: the VYTAL study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Ezetimibe; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Pyrroles; Simvastatin | 2006 |
Efficacy and safety of rosuvastatin 40 mg alone or in combination with ezetimibe in patients at high risk of cardiovascular disease (results from the EXPLORER study).
Topics: Aged; Azetidines; Cardiovascular Diseases; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ezetimibe; Female; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pyrimidines; Rosuvastatin Calcium; Sulfonamides; Treatment Outcome | 2007 |
Treatment with ezetimibe plus low-dose atorvastatin compared with higher-dose atorvastatin alone: is sufficient cholesterol-lowering enough to inhibit platelets?
Topics: Atorvastatin; Azetidines; Blood Chemical Analysis; Blood Platelets; Cholesterol, LDL; Coronary Artery Disease; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Ezetimibe; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Probability; Pyrroles; Reference Values; Risk Assessment; Severity of Illness Index; Survival Rate; Treatment Outcome | 2007 |
Efficacy and safety of ezetimibe co-administered with atorvastatin in untreated patients with primary hypercholesterolaemia and coronary heart disease.
Topics: Adult; Aged; Anticholesteremic Agents; Atorvastatin; Azetidines; Coronary Disease; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Placebos; Pyrroles; Treatment Outcome | 2007 |
Co-administration of ezetimibe and simvastatin in acute myocardial infarction.
Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Myocardial Infarction; Simvastatin; Triglycerides | 2007 |
Effects of ezetimibe on lipids and lipoproteins in patients with hypercholesterolemia and different apolipoprotein E genotypes.
Topics: Alleles; Anticholesteremic Agents; Apolipoproteins E; Azetidines; Ezetimibe; Female; Genotype; Humans; Hungary; Hypercholesterolemia; Lipid Metabolism; Lipids; Lipoproteins; Male; Middle Aged | 2007 |
A multi-centre, randomised, double-blind 14-week extension study examining the long-term safety and efficacy profile of the ezetimibe/simvastatin combination tablet.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Azetidines; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Drug Combinations; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Simvastatin; Tablets; Treatment Outcome | 2007 |
Reduction in estimated risk for coronary artery disease after use of ezetimibe with a statin.
Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Azetidines; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Coronary Artery Disease; Diabetes Mellitus; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Male; Metabolic Syndrome; Middle Aged; Risk | 2007 |
New medications which decrease levothyroxine absorption.
Topics: Adult; Anticholesteremic Agents; Azetidines; Chelating Agents; Drug Interactions; Ezetimibe; Female; Humans; Hypercholesterolemia; Hypothyroidism; Intestinal Absorption; Iron Chelating Agents; Male; Picolinic Acids; Polyamines; Sevelamer; Thyroxine | 2007 |
Ezetimibe treatment in hypercholesterolemic kidney transplant patients is safe and effective and reduces the decline of renal allograft function: a pilot study.
Topics: Anticholesteremic Agents; Azetidines; Case-Control Studies; Ezetimibe; Female; Humans; Hypercholesterolemia; Kidney Transplantation; Male; Middle Aged; Pilot Projects; Postoperative Complications; Prospective Studies | 2008 |
Effects of ezetimibe, simvastatin, atorvastatin, and ezetimibe-statin therapies on non-cholesterol sterols in patients with primary hypercholesterolemia.
Topics: Aged; Anticholesteremic Agents; Azetidines; Cholesterol; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Phytosterols; Placebos; Simvastatin; Sitosterols; Sterols | 2008 |
SREBP-1c gene polymorphism is associated with increased inhibition of cholesterol-absorption in response to ezetimibe treatment.
Topics: Adult; Anticholesteremic Agents; Azetidines; Cholesterol; Ezetimibe; Gene Frequency; Genotype; Humans; Hypercholesterolemia; Intestinal Absorption; Male; Polymorphism, Single Nucleotide; Regression Analysis; Simvastatin; Sterol Regulatory Element Binding Protein 1 | 2008 |
Effects of ezetimibe/simvastatin on lipoprotein subfractions in patients with primary hypercholesterolemia: an exploratory analysis of archived samples using two commercially available techniques.
Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Azetidines; Cholesterol; Cholesterol, LDL; Cholesterol, VLDL; Double-Blind Method; Drug Combinations; Endpoint Determination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoproteins; Male; Middle Aged; Particle Size; Simvastatin | 2007 |
Lipid-altering efficacy of ezetimibe/simvastatin 10/40 mg compared with doubling the statin dose in patients admitted to the hospital for a recent coronary event: the INFORCE study.
Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Azetidines; Dose-Response Relationship, Drug; Drug Combinations; Ezetimibe; Hospitalization; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Middle Aged; Myocardial Infarction; Simvastatin; Treatment Outcome | 2008 |
Effectiveness of ezetimibe alone or in combination with twice a week Atorvastatin (10 mg) for statin intolerant high-risk patients.
Topics: Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol, LDL; Coronary Artery Disease; Creatinine; Diabetes Mellitus; Drug Administration Schedule; Drug Therapy, Combination; Ezetimibe; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Peripheral Vascular Diseases; Prospective Studies; Pyrroles; Stroke | 2008 |
Effects of fluvastatin extended-release (80 mg) alone and in combination with ezetimibe (10 mg) on low-density lipoprotein cholesterol and inflammatory parameters in patients with primary hypercholesterolemia: a 12-week, multicenter, randomized, open-labe
Topics: Anticholesteremic Agents; Apolipoproteins B; Azetidines; Biomarkers; C-Reactive Protein; Cholesterol; Cholesterol, LDL; Delayed-Action Preparations; Drug Therapy, Combination; Ezetimibe; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Interleukin-1beta; Male; Middle Aged; Triglycerides | 2008 |
The impact of ezetimibe and high-dose of statin treatment on LDL levels in patients with heterozygous familial hypercholesterolemia.
Topics: Adult; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Female; Heterozygote; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged | 2009 |
Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia.
Topics: Aged; Anticholesteremic Agents; Azetidines; Benzimidazoles; Carrier Proteins; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Microsomes; Middle Aged; Severity of Illness Index; Treatment Outcome | 2008 |
The plasma concentration and LDL-C relationship in patients receiving ezetimibe.
Topics: Adolescent; Adult; Aged; Algorithms; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Chromatography, Liquid; Dose-Response Relationship, Drug; Ezetimibe; Female; Humans; Hypercholesterolemia; Linear Models; Male; Mass Spectrometry; Middle Aged | 2001 |
Effectiveness and tolerability of ezetimibe in patients with primary hypercholesterolemia: pooled analysis of two phase II studies.
Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Double-Blind Method; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Middle Aged | 2001 |
286 other study(ies) available for ezetimibe and Elevated Cholesterol
Article | Year |
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One-step modification to identify dual-inhibitors targeting both pancreatic triglyceride lipase and Niemann-Pick C1-like 1.
Topics: Anticholesteremic Agents; Binding Sites; Cell Line, Tumor; Drug Design; Ezetimibe; Gene Expression Regulation; Humans; Hypercholesterolemia; Lipase; Membrane Transport Proteins; Molecular Docking Simulation; Molecular Dynamics Simulation; Orlistat; Pancreas | 2021 |
Management of Severe and Moderate Hypercholesterolemia in Young Women and Men.
Topics: Adult; Anticholesteremic Agents; Cholesterol, LDL; Disease Management; Ezetimibe; Female; Guideline Adherence; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; PCSK9 Inhibitors; Practice Guidelines as Topic; Practice Patterns, Physicians'; Registries; Severity of Illness Index; Sex Factors; Young Adult | 2022 |
Ezetimibe and Insulin Resistance.
Topics: Anticholesteremic Agents; Ezetimibe; Humans; Hypercholesterolemia; Insulin Resistance | 2022 |
Plant sterol hyperabsorption caused by uncontrolled diabetes in a patient with a heterozygous ABCG5 variant.
Topics: ATP Binding Cassette Transporter, Subfamily G, Member 5; Diabetes Mellitus; Ezetimibe; Humans; Hypercholesterolemia; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Lipoproteins; Phytosterols | 2022 |
Effect of cholesterol-lowering agents on soluble epidermal growth factor receptor level in type 2 diabetes and hypercholesterolemia.
Topics: Anticholesteremic Agents; Cholesterol; Cholesterol, LDL; Diabetes Mellitus, Type 2; Drug Therapy, Combination; ErbB Receptors; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Rosuvastatin Calcium; Treatment Outcome | 2022 |
First Discovery of Cholesterol-Lowering Activity of Parthenolide as NPC1L1 Inhibitor.
Topics: Anticholesteremic Agents; Cholesterol; Ezetimibe; Filipin; Humans; Hypercholesterolemia; Hyperlipidemias; Membrane Transport Proteins; Molecular Docking Simulation; Sesquiterpenes | 2022 |
Establishment of a lipid metabolism disorder model in ApoEb mutant zebrafish.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Ezetimibe; Hypercholesterolemia; Hyperlipidemias; Lipid Metabolism; Mammals; Simvastatin; Zebrafish | 2022 |
Impact of physician's perception about LDL cholesterol control in clinical practice when treating patients in Spain.
Topics: Anticholesteremic Agents; Cholesterol, LDL; Cross-Sectional Studies; Dyslipidemias; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Perception; Proprotein Convertase 9; Spain; Treatment Outcome | 2023 |
Sitosterolaemia presenting with consistent skin xanthomas in a pair of monozygotic twins who responded to ezetimibe treatment.
Topics: Ezetimibe; Humans; Hypercholesterolemia; Twins, Monozygotic; Xanthomatosis | 2023 |
Guideline-Directed Low-Density Lipoprotein Cholesterol Management After Acute Ischemic Stroke: Findings from a National Health Care Service.
Topics: Anticholesteremic Agents; Cardiovascular Diseases; Cholesterol, LDL; Coronary Artery Disease; Delivery of Health Care; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Ischemic Stroke; Stroke | 2023 |
[Hypercholesterolemia and cardiovascular risk].
Topics: Anticholesteremic Agents; Atherosclerosis; Cardiovascular Diseases; Cholesterol, LDL; Ezetimibe; Heart Disease Risk Factors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipidemias; Proprotein Convertase 9; Risk Factors | 2023 |
Proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors.
Topics: Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Atherosclerosis; Cardiovascular Diseases; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; PCSK9 Inhibitors | 2019 |
Treatment of Hypercholesterolemia With PCSK9 Inhibitors in Heart Transplant Recipients. First Experience in Spain.
Topics: Aged; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Biomarkers; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Heart Transplantation; Humans; Hypercholesterolemia; Injections, Subcutaneous; Middle Aged; PCSK9 Inhibitors; Spain; Transplant Recipients; Treatment Outcome; Triglycerides | 2019 |
Pathophysiological importance of bile cholesterol reabsorption: hepatic NPC1L1-exacerbated steatosis and decreasing VLDL-TG secretion in mice fed a high-fat diet.
Topics: Animals; Azetidines; Bile; Cholesterol, VLDL; Diet, High-Fat; Ezetimibe; Fatty Liver; Gene Expression Regulation; Humans; Hypercholesterolemia; Intestinal Reabsorption; Liver; Membrane Transport Proteins; Mice; Mice, Transgenic; Triglycerides | 2019 |
Beneficial effect of ezetimibe-atorvastatin combination therapy in patients with a mutation in ABCG5 or ABCG8 gene.
Topics: Aged; Atorvastatin; ATP Binding Cassette Transporter, Subfamily G, Member 5; ATP Binding Cassette Transporter, Subfamily G, Member 8; Cholesterol, LDL; Drug Combinations; Ezetimibe; Female; Humans; Hypercholesterolemia; Lipoproteins; Male; Middle Aged; Mutation | 2020 |
Optimizing Clinical Cardiovascular Outcomes by a Personalized Approach to Add Ezetimibe to a Statin.
Topics: Anticholesteremic Agents; Biomarkers; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia | 2020 |
Impact of Lipid Monitoring on Treatment Intensification of Cholesterol Lowering Therapies (from the Veterans Affairs Healthcare System).
Topics: Aged; Aged, 80 and over; Anticholesteremic Agents; Atherosclerosis; Cardiovascular Diseases; Cholesterol, LDL; Ezetimibe; Female; Guideline Adherence; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Male; Middle Aged; Monitoring, Physiologic; Odds Ratio; Treatment Outcome; United States; Veterans Health Services | 2020 |
[Ezetimibe-rosuvastatin fixed-dose combination (Myrosor®)].
Topics: Anticholesteremic Agents; Belgium; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Rosuvastatin Calcium; Treatment Outcome | 2020 |
A practical approach to the cholesterol guidelines and ASCVD prevention.
Topics: Age Factors; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Atherosclerosis; Autoimmune Diseases; Cholesterol, HDL; Cholesterol, LDL; Coronary Artery Disease; Diabetes Mellitus; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; PCSK9 Inhibitors; Practice Guidelines as Topic; Primary Prevention; Risk Assessment; Risk Reduction Behavior; Secondary Prevention; Vascular Calcification | 2020 |
A case of ezetimibe-effective hypercholesterolemia with a novel heterozygous variant in ABCG5.
Topics: Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 5; Cholesterol; Cholesterol, LDL; Diagnostic Errors; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipoproteinemia Type II; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Lipoproteins; Loss of Function Mutation; Middle Aged; Phytosterols; Sitosterols; Treatment Failure | 2020 |
Sitosterolemia Exhibiting Severe Hypercholesterolemia with Tendon Xanthomas Due to Compound Heterozygous ABCG5 Gene Mutations Treated with Ezetimibe and Alirocumab.
Topics: Achilles Tendon; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 5; Cholesterol, LDL; Ezetimibe; Humans; Hypercholesterolemia; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Male; Middle Aged; Mutation; Phytosterols; Treatment Outcome; Xanthomatosis | 2020 |
Non-statin lipid-lowering therapy over time in very-high-risk patients: effectiveness of fixed-dose statin/ezetimibe compared to separate pill combination on LDL-C.
Topics: Aged; Anticholesteremic Agents; Atherosclerosis; Cholesterol, LDL; Cross-Sectional Studies; Drug Prescriptions; Drug Therapy, Combination; Ezetimibe; Female; General Practice; Germany; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Practice Patterns, Physicians'; Retrospective Studies; Time Factors; Treatment Outcome | 2022 |
Low-density lipoprotein cholesterol reduction and target achievement after switching from statin monotherapy to statin/ezetimibe combination therapy: Real-world evidence.
Topics: Cholesterol, LDL; Drug Therapy, Combination; Electronic Health Records; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Republic of Korea; Retrospective Studies; Treatment Outcome | 2021 |
Lipid-lowering therapies: Better together.
Topics: Atorvastatin; Dicarboxylic Acids; Ezetimibe; Fatty Acids; Humans; Hypercholesterolemia | 2021 |
LDL Cholesterol Reduction Variability with Different Types and Doses of Statins in Monotherapy or Combined with Ezetimibe. Results from the Spanish Arteriosclerosis Society Dyslipidaemia Registry.
Topics: Anticholesteremic Agents; Arteriosclerosis; Cholesterol, LDL; Drug Therapy, Combination; Dyslipidemias; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Registries; Rosuvastatin Calcium; Simvastatin | 2022 |
Similarities and differences between European and American guidelines on the management of blood lipids to reduce cardiovascular risk.
Topics: Anticholesteremic Agents; Cardiovascular Diseases; Cholesterol, LDL; Diabetes Mellitus; Europe; Ezetimibe; Heart Disease Risk Factors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertriglyceridemia; PCSK9 Inhibitors; Practice Guidelines as Topic; Primary Prevention; Renal Insufficiency, Chronic; United States | 2020 |
Comment on 'Bempedoic Acid and Ezetimibe for the Treatment of Hypercholesterolemia: A Systematic Review and Meta-Analysis of Randomized Phase II/III trials'.
Topics: Dicarboxylic Acids; Ezetimibe; Fatty Acids; Humans; Hypercholesterolemia | 2021 |
Authors' Reply to 'Comment on: Bempedoic Acid and Ezetimibe for the Treatment of Hypercholesterolemia: A Systematic Review and Meta-Analysis of Randomized Phase II/III Trials'.
Topics: Dicarboxylic Acids; Ezetimibe; Fatty Acids; Humans; Hypercholesterolemia | 2021 |
Impact of Lower Versus Higher LDL Cholesterol Targets on Cardiovascular Events After Ischemic Stroke in Patients With Diabetes.
Topics: Aged; Cholesterol, LDL; Diabetes Mellitus, Type 2; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Ischemic Stroke; Male; Middle Aged; Myocardial Infarction; Treatment Outcome | 2021 |
Rosuvastatin and ezetimibe for the treatment of dyslipidemia and hypercholesterolemia.
Topics: Adult; Anticholesteremic Agents; Drug Therapy, Combination; Dyslipidemias; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Rosuvastatin Calcium; Treatment Outcome | 2021 |
Don't we forget about biological therapy of hypercholesterolemia with PCSK9-inhibitors?
Topics: Anticholesteremic Agents; Biological Therapy; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Proprotein Convertase 9 | 2021 |
Regulation of the expression of cholesterol transporters by lipid-lowering drugs ezetimibe and pemafibrate in rat liver and intestine.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 5; ATP Binding Cassette Transporter, Subfamily G, Member 8; Benzoxazoles; Butyrates; Cholesterol; Ezetimibe; Hepatobiliary Elimination; Humans; Hypercholesterolemia; Hypolipidemic Agents; Intestinal Absorption; Intestinal Mucosa; Lipoproteins; Liver; Male; Membrane Transport Proteins; Rats; Scavenger Receptors, Class B | 2021 |
Effect of ezetimibe on low- and high-density lipoprotein subclasses in sitosterolemia.
Topics: Adolescent; Adult; Anticholesteremic Agents; Cholesterol, HDL; Electrophoresis, Polyacrylamide Gel; Ezetimibe; Female; Humans; Hypercholesterolemia; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Lipoproteins, HDL; Lipoproteins, IDL; Lipoproteins, VLDL; Male; Middle Aged; Phytosterols; Treatment Outcome; Young Adult | 2017 |
Antiatherogenic potential of ezetimibe in sitosterolemia: Beyond plant sterols lowering.
Topics: Ezetimibe; Humans; Hypercholesterolemia; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Lipoproteins, HDL; Phytosterols | 2017 |
Efficacy of alirocumab according to background statin type and dose: pooled analysis of 8 ODYSSEY Phase 3 clinical trials.
Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Clinical Trials as Topic; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Proprotein Convertase 9; Rosuvastatin Calcium; Simvastatin | 2017 |
How has the treatment of hypercholesterolemia in Poland changed over the last six years?
Topics: Anticholesteremic Agents; Atorvastatin; Cholesterol; Drug Therapy, Combination; Ezetimibe; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Incidence; Lipoproteins, LDL; Male; Middle Aged; Patient Compliance; Poland; Registries; Retrospective Studies; Rosuvastatin Calcium; Simvastatin; Surveys and Questionnaires; Time Factors | 2017 |
Modelling the cost-effectiveness of PCSK9 inhibitors vs. ezetimibe through LDL-C reductions in a Norwegian setting.
Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Cardiovascular Diseases; Cholesterol, LDL; Cost-Benefit Analysis; Ezetimibe; Female; Humans; Hypercholesterolemia; Incidence; Middle Aged; Norway; PCSK9 Inhibitors; Risk Factors; Secondary Prevention | 2018 |
Access to Nonstatin Lipid-Lowering Therapies in Patients at High Risk of Atherosclerotic Cardiovascular Disease.
Topics: Anticholesteremic Agents; Atherosclerosis; Cholesterol, LDL; Databases, Factual; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; PCSK9 Inhibitors | 2017 |
Timely diagnosis of sitosterolemia by next generation sequencing in two children with severe hypercholesterolemia.
Topics: Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 5; ATP Binding Cassette Transporter, Subfamily G, Member 8; Biomarkers; Child; Child, Preschool; Cholesterol, LDL; Codon, Nonsense; Diet, Fat-Restricted; DNA Mutational Analysis; Ezetimibe; Female; Genetic Predisposition to Disease; Heterozygote; High-Throughput Nucleotide Sequencing; Humans; Hypercholesterolemia; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Lipoproteins; Male; Phenotype; Phytosterols; Predictive Value of Tests; Severity of Illness Index; Treatment Outcome; Up-Regulation | 2017 |
Low-Density Lipoprotein Cholesterol and Drug Treatment to Lower Atherosclerotic Cardiovascular Disease Risk: Where Do We Stand?
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Atherosclerosis; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Patient Selection; PCSK9 Inhibitors; Risk Reduction Behavior; RNA, Small Interfering | 2017 |
Low-Density Lipoprotein Cholesterol Treatment in the Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitor Era: Getting Back on Target.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Atherosclerosis; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Patient Care Planning; PCSK9 Inhibitors; Practice Guidelines as Topic; Primary Prevention; Risk Reduction Behavior; Secondary Prevention | 2017 |
Simulation of Lipid-Lowering Therapy Intensification in a Population With Atherosclerotic Cardiovascular Disease.
Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Atherosclerosis; Atorvastatin; Cholesterol, LDL; Cohort Studies; Computer Simulation; Databases, Factual; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Monte Carlo Method; Patient Care Planning; PCSK9 Inhibitors | 2017 |
Carotid intima media thickness in a girl with sitosterolemia carrying a homozygous mutation in the ABCG5 gene.
Topics: Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 5; Carotid Arteries; Carotid Intima-Media Thickness; Child, Preschool; Cholesterol, LDL; Echocardiography; Ezetimibe; Female; Humans; Hypercholesterolemia; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Lipoproteins; Mutation; Phytosterols | 2017 |
2017 Focused Update of the 2016 ACC Expert Consensus Decision Pathway on the Role of Non-Statin Therapies for LDL-Cholesterol Lowering in the Management of Atherosclerotic Cardiovascular Disease Risk: A Report of the American College of Cardiology Task Fo
Topics: Anticholesteremic Agents; Cardiology; Chemoprevention; Cholesterol, LDL; Consensus; Coronary Artery Disease; Enzyme Inhibitors; Ezetimibe; Humans; Hypercholesterolemia; Medication Therapy Management; Sequestering Agents; United States | 2017 |
Statin and ezetimibe combination therapy: New therapeutic options for lowering Low-Density Lipoprotein Cholesterol.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia | 2017 |
Using genetics to explore whether the cholesterol-lowering drug ezetimibe may cause an increased risk of cancer.
Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol, LDL; Denmark; Ezetimibe; Female; Genetic Variation; Humans; Hypercholesterolemia; Male; Membrane Proteins; Membrane Transport Proteins; Mendelian Randomization Analysis; Middle Aged; Neoplasms; Proportional Hazards Models; Risk Assessment; Risk Factors | 2017 |
The natural history of phytosterolemia: Observations on its homeostasis.
Topics: Adolescent; Adult; Age Factors; Anticholesteremic Agents; Asymptomatic Diseases; ATP Binding Cassette Transporter, Subfamily G, Member 8; Biomarkers; Canada; Child; Child, Preschool; Cholesterol; Ezetimibe; Female; Genetic Predisposition to Disease; Homeostasis; Humans; Hypercholesterolemia; Infant; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Male; Middle Aged; Mutation; Phenotype; Phytosterols; Prevalence; Puberty; Rare Diseases; Risk Factors; Sitosterols; Time Factors; Treatment Outcome; United States; Young Adult | 2018 |
Prescribing Patterns of Proprotein Convertase Subtilisin-Kexin Type 9 Inhibitors in Eligible Patients With Clinical Atherosclerotic Cardiovascular Disease or Heterozygous Familial Hypercholesterolemia.
Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Atherosclerosis; Cholesterol, LDL; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipoproteinemia Type II; Male; Middle Aged; PCSK9 Inhibitors; Practice Patterns, Physicians'; Retrospective Studies | 2018 |
Newer cholesterol-lowering agents: What you must know.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Anticholesteremic Agents; Cholesterol; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; PCSK9 Inhibitors; Proprotein Convertase 9 | 2018 |
Impact of statin-ezetimibe combination in chronic kidney disease.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Renal Insufficiency, Chronic; Treatment Outcome | 2018 |
[Newer evidences and recommendations in lipidology].
Topics: Anticholesteremic Agents; Cholesterol, LDL; Ezetimibe; Female; Humans; Hungary; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Plaque, Atherosclerotic | 2018 |
2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.
Topics: American Heart Association; Anticholesteremic Agents; Biomarkers; Cardiology; Cardiovascular Diseases; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Medication Therapy Management; PCSK9 Inhibitors; Risk Assessment; Risk Reduction Behavior; United States | 2019 |
2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.
Topics: American Heart Association; Anticholesteremic Agents; Biomarkers; Cardiology; Cardiovascular Diseases; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Medication Therapy Management; PCSK9 Inhibitors; Risk Assessment; Risk Reduction Behavior; United States | 2019 |
Lipoprotein (a) and Low-density lipoprotein apolipoprotein B metabolism following apheresis in patients with elevated lipoprotein(a) and coronary artery disease.
Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Apolipoproteins B; Aspirin; Blood Component Removal; Coronary Artery Disease; Cross-Sectional Studies; Ezetimibe; Female; Fish Oils; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoprotein(a); Lipoproteins, LDL; Male; Middle Aged; Platelet Aggregation Inhibitors; Young Adult | 2019 |
A closer look at an ezetimibe discussion.
Topics: Anticholesteremic Agents; Cholesterol; Ezetimibe; Humans; Hypercholesterolemia | 2018 |
The important role of apolipoprotein A-II in ezetimibe driven reduction of high cholesterol diet-induced atherosclerosis.
Topics: Animals; Animals, Genetically Modified; Anticholesteremic Agents; Apolipoprotein A-II; Atherosclerosis; Cholesterol; Diet, High-Fat; Endothelial Cells; Ezetimibe; Granulocytes; Hep G2 Cells; Hepatocyte Nuclear Factor 4; Hepatocytes; Humans; Hypercholesterolemia; Lipid Metabolism; Lipids; Macrophages; Microscopy, Confocal; PPAR alpha; THP-1 Cells; Zebrafish | 2019 |
Cost-effectiveness of Evolocumab.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cost-Benefit Analysis; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Proprotein Convertase 9; Spain | 2018 |
Lipid-lowering effects of Coffea arabica pulp aqueous extract in Caco-2 cells and hypercholesterolemic rats.
Topics: Animals; Anticholesteremic Agents; Caco-2 Cells; Cholesterol; Coffea; Down-Regulation; Ezetimibe; Humans; Hypercholesterolemia; Intestinal Absorption; Jejunum; Liver X Receptors; Male; Membrane Proteins; Membrane Transport Proteins; Micelles; Plant Extracts; Rats; Rats, Wistar | 2019 |
Overview of Therapeutic Approaches for Cholesterol Lowering and Attenuation of Thrombosis for Prevention of Atherothrombosis.
Topics: Anticholesteremic Agents; Aspirin; Cholesterol, LDL; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; PCSK9 Inhibitors; Plaque, Atherosclerotic; Rivaroxaban; Thrombosis | 2019 |
Combined Effect of Diosgenin Along with Ezetimibe or Atorvastatin on the Fate of Labelled Bile Acid and Cholesterol in Hypercholesterolemic Rats.
Topics: Animals; Anticholesteremic Agents; Atorvastatin; Bile Acids and Salts; Cholesterol; Diosgenin; Ezetimibe; Hypercholesterolemia; Liver; Male; Rats; Rats, Wistar | 2019 |
Clinical characteristics and lipid lowering treatment of patients initiated on proprotein convertase subtilisin-kexin type 9 inhibitors: a nationwide cohort study.
Topics: Aged; Anticholesteremic Agents; Cholesterol, LDL; Denmark; Diabetes Mellitus; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Myocardial Ischemia; PCSK9 Inhibitors; Practice Patterns, Physicians'; Stroke | 2019 |
Four Cases of Cholesterol Management Informed by the 2018 American Heart Association/American College of Cardiology Multisociety Guideline on the Management of Blood Cholesterol.
Topics: Adult; American Heart Association; Anticholesteremic Agents; Atherosclerosis; Cardiology; Cardiovascular Diseases; Cholesterol, LDL; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Practice Guidelines as Topic; Primary Prevention; Secondary Prevention; United States | 2019 |
[Eligibility for the indication of PCSK9 inhibitors according to the recommendations of different scientific societies].
Topics: Age Factors; Aged; Aged, 80 and over; Anticholesteremic Agents; Argentina; Cross-Sectional Studies; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; PCSK9 Inhibitors; Practice Guidelines as Topic; Sex Factors; Societies, Scientific; Statistics, Nonparametric; Time Factors; Treatment Outcome | 2019 |
Hypercholesterolemia Among Premature Infarcts: Time to Start the Clock of Familial Hypercholesterolemia Assessment.
Topics: Ezetimibe; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Infarction; Myocardial Infarction; Proprotein Convertase 9; Young Adult | 2019 |
Bempedoic acid and ezetimibe - better together.
Topics: Cardiovascular Diseases; Dicarboxylic Acids; Ezetimibe; Fatty Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia | 2020 |
[Screening for hyperlipidemia in cardiovascular high-risk patients in austrian diabetes ambulances].
Topics: Ambulatory Care; Anticholesteremic Agents; Austria; Azetidines; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Drug Utilization; Ezetimibe; Fibric Acids; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Mass Screening; Risk Factors; Treatment Outcome; Triglycerides | 2012 |
Bayesian inference for multivariate meta-analysis Box-Cox transformation models for individual patient data with applications to evaluation of cholesterol-lowering drugs.
Topics: Adult; Azetidines; Bayes Theorem; Cholesterol, HDL; Cholesterol, LDL; Clinical Trials as Topic; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Markov Chains; Meta-Analysis as Topic; Models, Statistical; Monte Carlo Method; Multivariate Analysis; Triglycerides | 2013 |
Ezetimibe decreases serum oxidized cholesterol without impairing bile acid synthesis in Japanese hypercholesterolemic patients.
Topics: Absorption; Aged; Anthropometry; Anticholesteremic Agents; Azetidines; Bile Acids and Salts; Body Mass Index; Case-Control Studies; Cholesterol; Diet; Ezetimibe; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydroxycholesterols; Hypercholesterolemia; Intestine, Small; Japan; Life Style; Male; Middle Aged; Oxygen; Phytosterols; Sterols; Triglycerides | 2013 |
Development of optimized supersaturable self-nanoemulsifying systems of ezetimibe: effect of polymers and efflux transporters.
Topics: Animals; Anticholesteremic Agents; Azetidines; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Cholesterol, LDL; Disease Models, Animal; Drug Delivery Systems; Drug Stability; Emulsions; Ezetimibe; Female; Hypercholesterolemia; Intestinal Absorption; Intestine, Small; Lipids; Nanoparticles; Polymers; Rats; Rats, Sprague-Dawley; X-Ray Diffraction | 2014 |
Use and misuse of ezetimibe: analysis of use and cost in Saskatchewan, a Canadian jurisdiction with broad access.
Topics: Aged; Anticholesteremic Agents; Azetidines; Drug Costs; Drug Prescriptions; Drug Utilization; Ezetimibe; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Male; Middle Aged; Prescription Drug Misuse; Retrospective Studies; Saskatchewan | 2014 |
Impact of currently prescribed lipid-lowering drugs on plasma PCSK9 concentration: single or in combination study in rats.
Topics: Animals; Azetidines; Drug Combinations; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Ezetimibe; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Proprotein Convertase 9; Quinolines; Rats; Rats, Sprague-Dawley; Serine Endopeptidases | 2014 |
A novel mutation of ABCG5 gene in a Turkish boy with phytosterolemia presenting with macrotrombocytopenia and stomatocytosis.
Topics: Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 5; ATP Binding Cassette Transporter, Subfamily G, Member 8; ATP-Binding Cassette Transporters; Azetidines; Child; Ezetimibe; Hematologic Diseases; Humans; Hypercholesterolemia; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Lipoproteins; Male; Phytosterols; Point Mutation | 2014 |
Characterization of the pharmaceutical effect of drugs on atherosclerotic lesions in vivo using integrated fluorescence imaging and Raman spectral measurements.
Topics: Animals; Anticholesteremic Agents; Atherosclerosis; Atorvastatin; Azetidines; Blood Vessels; Ezetimibe; Heptanoic Acids; Hypercholesterolemia; Lipid Metabolism; Lipids; Microscopy, Confocal; Pyrroles; Spectrum Analysis, Raman; Zebrafish | 2014 |
Ezetimibe prescribing fails to keep up with evidence.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Evidence-Based Medicine; Ezetimibe; Humans; Hypercholesterolemia; Practice Guidelines as Topic; Practice Patterns, Physicians'; Prescriptions; Randomized Controlled Trials as Topic; United States | 2014 |
Use of targeted exome sequencing in genetic diagnosis of Chinese familial hypercholesterolemia.
Topics: Anticholesteremic Agents; Asian People; Azetidines; Child, Preschool; China; DNA Mutational Analysis; Drug Therapy, Combination; Exome; Ezetimibe; Genotype; Humans; Hypercholesterolemia; Male; Mutation; Pedigree; Phenotype; Simvastatin; Treatment Outcome | 2014 |
Effects of atorvastatin in combination with ezetimibe on carotid atherosclerosis in elderly patients with hypercholesterolemia.
Topics: Aged; Atorvastatin; Azetidines; C-Reactive Protein; Carotid Artery Diseases; Carotid Intima-Media Thickness; Cholesterol, LDL; Drug Combinations; Ezetimibe; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Pyrroles | 2014 |
The influence of ezetimibe on classical and alternative activation pathways of monocytes/macrophages isolated from patients with hypercholesterolemia.
Topics: Anticholesteremic Agents; Arginase; Azetidines; Cell Survival; Cells, Cultured; Ezetimibe; Female; Humans; Hypercholesterolemia; Interleukin-1beta; Lectins, C-Type; Lipopolysaccharides; Macrophages; Male; Mannose Receptor; Mannose-Binding Lectins; Middle Aged; Monocytes; Nitric Oxide; Nitric Oxide Synthase Type II; Receptors, Cell Surface | 2014 |
The effect of ezetimibe on adipose tissue hormones in patients with isolated hypercholesterolemia.
Topics: Adiponectin; Adipose Tissue; Anticholesteremic Agents; Apolipoproteins; Azetidines; Biomarkers; C-Reactive Protein; Case-Control Studies; Cholesterol; Cholesterol, LDL; Ezetimibe; Fatty Acids, Nonesterified; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Male; Middle Aged; Nicotinamide Phosphoribosyltransferase; Tumor Necrosis Factor-alpha | 2014 |
Hypercholesterolemia induces angiogenesis and accelerates growth of breast tumors in vivo.
Topics: Animals; Apoptosis; Azetidines; Cell Line, Tumor; Cell Proliferation; Cholesterol; Cholesterol, Dietary; Diet, High-Fat; Ezetimibe; Female; Humans; Hypercholesterolemia; Mammary Neoplasms, Experimental; Mice, SCID; Neoplasm Transplantation; Neovascularization, Pathologic | 2014 |
The effect of ezetimibe on androgen production in hypercholesterolemic women with polycystic ovary syndrome.
Topics: Adult; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Ezetimibe; Female; Humans; Hypercholesterolemia; Insulin Resistance; Middle Aged; Polycystic Ovary Syndrome; Simvastatin; Testosterone | 2014 |
Trends in use of ezetimibe after the ENHANCE trial, 2007 through 2010.
Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Atherosclerosis; Azetidines; Clinical Trials as Topic; Disease Progression; Ezetimibe; Female; Humans; Hypercholesterolemia; Insurance, Pharmaceutical Services; Male; Middle Aged; Retrospective Studies; Simvastatin; Treatment Outcome; United States | 2014 |
20-year-old amish woman with abdominal pain, retroperitoneal mass, and hyperlipidemia.
Topics: Abdominal Pain; Amish; Anticholesteremic Agents; Azetidines; Biopsy; Diagnosis, Differential; Ezetimibe; Female; Humans; Hypercholesterolemia; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Phytosterols; Predictive Value of Tests; Retroperitoneal Fibrosis; Retroperitoneal Space; Tomography, X-Ray Computed; Treatment Outcome; Xanthomatosis; Young Adult | 2015 |
Cholesterol treatment patterns and cardiovascular clinical outcomes associated with colesevelam HCl and ezetimibe.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allylamine; Anticholesteremic Agents; Azetidines; Cohort Studies; Colesevelam Hydrochloride; Coronary Artery Disease; Diagnosis-Related Groups; Ezetimibe; Female; Health Services for the Aged; Humans; Hypercholesterolemia; Male; Middle Aged; Retrospective Studies; Treatment Outcome; United States | 2014 |
The effect of short-term combined treatment with simvastatin and ezetimibe on circulating adipokine levels in patients with isolated hypercholesterolemia.
Topics: Adipokines; Anticholesteremic Agents; C-Reactive Protein; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Simvastatin | 2014 |
The effect of atorvastatin and atorvastatin-ezetimibe combination therapy on androgen production in hyperandrogenic women with elevated cholesterol levels.
Topics: Adult; Androgens; Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol; Drug Therapy, Combination; Ezetimibe; Female; Heptanoic Acids; Humans; Hyperandrogenism; Hypercholesterolemia; Middle Aged; Pyrroles; Sex Hormone-Binding Globulin; Treatment Outcome; Young Adult | 2015 |
Ezetimibe use remains common among medical inpatients.
Topics: Aged; Aged, 80 and over; Anticholesteremic Agents; Azetidines; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Inpatients; Middle Aged; Practice Patterns, Physicians'; Quebec | 2015 |
Achieving goal lipid levels with ezetimibe plus statin add-on or switch therapy compared with doubling the statin dose. A pooled analysis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Apolipoproteins B; Azetidines; Cholesterol, HDL; Cholesterol, LDL; Dose-Response Relationship, Drug; Double-Blind Method; Ezetimibe; Female; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Male; Middle Aged; Pyrimidines; Randomized Controlled Trials as Topic; Research Design; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Treatment Outcome; Young Adult | 2014 |
Efficacy of ezetimibe is not related to NPC1L1 gene polymorphisms in a pilot study of Chilean hypercholesterolemic subjects.
Topics: Adult; Anticholesteremic Agents; Azetidines; Biological Transport; Chile; Cholesterol, LDL; Ezetimibe; Female; Gene Expression; Genotype; Humans; Hypercholesterolemia; Intestinal Absorption; Male; Membrane Proteins; Membrane Transport Proteins; Middle Aged; Pilot Projects; Polymorphism, Genetic; Treatment Outcome | 2015 |
[Low persistence of simvastatin and ezetimibe fixed combination in the lipid lowering therapy].
Topics: Adult; Aged; Anticholesteremic Agents; Azetidines; Cardiovascular Diseases; Drug Administration Schedule; Drug Combinations; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Kaplan-Meier Estimate; Male; Medication Adherence; Middle Aged; Odds Ratio; Proportional Hazards Models; Retrospective Studies; Risk Factors; Simvastatin; Treatment Outcome | 2015 |
[Which patient will now actually benefit from ezetimib?].
Topics: Acute Coronary Syndrome; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Ezetimibe; Humans; Hypercholesterolemia; Randomized Controlled Trials as Topic | 2014 |
Impact of Switching From High-Efficacy Lipid-Lowering Therapies to Generic Simvastatin on LDL-C Levels and LDL-C Goal Attainment Among High-Risk Primary and Secondary Prevention Populations in the United Kingdom.
Topics: Aged; Aged, 80 and over; Atorvastatin; Cardiovascular Diseases; Cholesterol, LDL; Cohort Studies; Drugs, Generic; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Retrospective Studies; Risk Factors; Rosuvastatin Calcium; Secondary Prevention; Simvastatin; United Kingdom | 2015 |
Splenic extrafollicular reactions and BM plasma cells sustain IgM response associated with hypercholesterolemia.
Topics: Animals; Anticholesteremic Agents; Apolipoproteins E; Atherosclerosis; Autoantibodies; Azetidines; Bone Marrow Cells; Cholesterol; Ezetimibe; Hypercholesterolemia; Immunoglobulin M; Lipoproteins, LDL; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Plasma Cells; Spleen | 2015 |
IMPROVE-IT clinical implications. Should the "high-intensity cholesterol-lowering therapy" strategy replace the "high-intensity statin therapy"?
Topics: Anticholesteremic Agents; Biomarkers; Cardiovascular Diseases; Cholesterol; Clinical Trials as Topic; Down-Regulation; Drug Therapy, Combination; Evidence-Based Medicine; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Practice Guidelines as Topic; Risk Assessment; Risk Factors; Treatment Outcome | 2015 |
Evolocumab (AMG 145) for primary hypercholesterolemia.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Cholesterol, LDL; Ezetimibe; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lipids; Proprotein Convertase 9; Proprotein Convertases; Serine Endopeptidases | 2015 |
Genetic variation in the cholesterol transporter NPC1L1, ischaemic vascular disease, and gallstone disease.
Topics: Aged; Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 8; ATP-Binding Cassette Transporters; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Female; Gallstones; Genetic Variation; Genotype; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Ischemia; Lipid Metabolism; Male; Membrane Proteins; Membrane Transport Proteins; Mendelian Randomization Analysis; Middle Aged; Myocardial Infarction; Risk Factors; Stroke | 2015 |
Impact of Ezetimibe Alone or in Addition to a Statin on Plasma PCSK9 Concentrations in Patients with Type 2 Diabetes and Hypercholesterolemia: A Pilot Study.
Topics: Aged; Anticholesteremic Agents; Cholesterol, LDL; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pilot Projects; Proprotein Convertase 9; Proprotein Convertases; Prospective Studies; Serine Endopeptidases | 2015 |
Variability of the LDL-C lowering response to ezetimibe and ezetimibe + statin therapy in hypercholesterolemic patients.
Topics: Anticholesteremic Agents; Biomarkers; Cholesterol, LDL; Down-Regulation; Drug Combinations; Evidence-Based Medicine; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Time Factors; Treatment Outcome | 2015 |
[LDL cholesterol lowering therapy: no target value but personalised treatment].
Topics: Anticholesteremic Agents; Azetidines; Cardiovascular Diseases; Cholesterol, LDL; Cost-Benefit Analysis; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Simvastatin | 2015 |
Comparison of the effects of short-term hypolipidaemic treatment on plasma adipokine levels in men and women with isolated hypercholesterolaemia.
Topics: Adipokines; Adipose Tissue; Animals; Anticholesteremic Agents; C-Reactive Protein; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Rabbits; Retrospective Studies; Sex Factors; Tumor Necrosis Factor-alpha | 2015 |
[The surprising (?) results of IMPROVE-IT].
Topics: Anticholesteremic Agents; Azetidines; Biomarkers; Cardiovascular Diseases; Cholesterol, LDL; Clinical Trials as Topic; Congresses as Topic; Ezetimibe; Global Health; Humans; Hypercholesterolemia; Incidence; Italy; Meta-Analysis as Topic; Risk Assessment; Risk Factors; Simvastatin; Treatment Outcome; United States | 2015 |
Associations of ApoAI and ApoB-containing lipoproteins with AngII-induced abdominal aortic aneurysms in mice.
Topics: Angiotensin II; Animals; Anticholesteremic Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoprotein A-I; Apolipoprotein B-100; Apolipoproteins B; Apolipoproteins E; Azetidines; Diet, Western; Disease Models, Animal; Ezetimibe; Female; Hypercholesterolemia; Male; Mice, Inbred C57BL; Mice, Knockout; Receptors, LDL; Sex Factors | 2015 |
Vascular and metabolic effects of ezetimibe combined with simvastatin in patients with hypercholesterolemia.
Topics: Adiponectin; Aged; Animals; Anticholesteremic Agents; Blood Pressure; C-Reactive Protein; Drug Therapy, Combination; Ezetimibe; Fat Body; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Hypolipidemic Agents; Insulin; Insulin Resistance; Male; Middle Aged; Randomized Controlled Trials as Topic; Rats; Simvastatin; Single-Blind Method | 2015 |
Sociodemographic and diagnostic characteristics of prescribing a second-line lipid-lowering medication: ezetimibe used as initial medication, switch from statins, or add-on medication.
Topics: Adult; Age Distribution; Aged; Aged, 80 and over; Anticholesteremic Agents; Comorbidity; Denmark; Drug Therapy, Combination; Drug Utilization; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Logistic Models; Male; Middle Aged; Odds Ratio; Practice Patterns, Physicians'; Sex Distribution; Socioeconomic Factors | 2015 |
Statin-Ezetimibe Combination Therapy In Diabetic Individuals.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Diabetes Mellitus; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia | 2016 |
Reply to comment on: Effects of ezetimibe/simvastatin combination on metabolic parameters by Prof. Moses S Elisaf.
Topics: Animals; Anticholesteremic Agents; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Male; Simvastatin | 2016 |
Effects of ezetimibe/simvastatin combination on metabolic parameters.
Topics: Animals; Anticholesteremic Agents; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Male; Simvastatin | 2016 |
Intensive LDL lowering therapy for prevention of recurrent cardiovascular events: a word of caution.
Topics: Anticholesteremic Agents; Cardiovascular Diseases; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; PCSK9 Inhibitors; Secondary Prevention; Simvastatin; Treatment Outcome | 2016 |
Might ezetimibe be considered an expensive placebo?
Topics: Cardiovascular Diseases; Clinical Trials as Topic; Ezetimibe; Humans; Hypercholesterolemia; Lipids; Placebo Effect; Treatment Outcome | 2016 |
Maximum Low-density Lipoprotein Cholesterol Lowering Capacity Achievable With Drug Combinations. When 50 Plus 20 Equals 60.
Topics: Anticholesteremic Agents; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Treatment Outcome | 2016 |
New Studies Do Not Challenge the American College of Cardiology/American Heart Association Lipid Guidelines.
Topics: American Heart Association; Anticholesteremic Agents; Cardiology; Cardiovascular Diseases; Cholesterol, LDL; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; PCSK9 Inhibitors; Practice Guidelines as Topic; Proprotein Convertase 9; Risk Factors; Societies, Medical; United States | 2016 |
Age may determine the effect of hypolipidemic agents on plasma adipokine levels in patients with elevated low-density lipoprotein cholesterol levels.
Topics: Adipokines; Adipose Tissue; Adult; Age Factors; Aged; C-Reactive Protein; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hypercholesterolemia; Hypolipidemic Agents; Male; Middle Aged; Nicotinamide Phosphoribosyltransferase; Retrospective Studies; Simvastatin | 2016 |
[FIXED COMBINATION ATORVASTATIN-EZETIMIBE (ATOZET®)].
Topics: Anticholesteremic Agents; Atorvastatin; Cardiovascular Diseases; Drug Combinations; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Risk Factors | 2016 |
PCSK9 Inhibitors for Statin Intolerance?
Topics: Antibodies, Monoclonal; Anticholesteremic Agents; Cholesterol, LDL; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Muscular Diseases | 2016 |
Alternatives to statins in intolerant patients do lower cholesterol, study finds.
Topics: Antibodies, Monoclonal; Anticholesteremic Agents; Cholesterol, LDL; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Muscular Diseases | 2016 |
Ezetimibe-sensitive cholesterol uptake by NPC1L1 protein does not require endocytosis.
Topics: Biological Transport; Cell Line; Cholesterol; Endocytosis; Ezetimibe; Hepatocytes; Humans; Hypercholesterolemia; Intestinal Absorption; Liver; Membrane Proteins; Membrane Transport Proteins; Protein Binding; Protein Interaction Domains and Motifs; Protein Transport | 2016 |
[ANMCO Position paper: Clinical management of hypercholesterolemia in patients with acute coronary syndrome].
Topics: Acute Coronary Syndrome; Anticholesteremic Agents; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Italy; Treatment Outcome | 2016 |
Adding Ezetimibe to Simvastatin for the Secondary Prevention of Cardiovascular Disease: Is it Useful?
Topics: Anticholesteremic Agents; Cardiovascular Diseases; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Secondary Prevention; Simvastatin | 2016 |
Reply: Adding Ezetimibe to Simvastatin for the Secondary Prevention of Cardiovascular Disease: Is it Useful?
Topics: Anticholesteremic Agents; Cardiovascular Diseases; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Secondary Prevention; Simvastatin | 2016 |
A study in high-risk, maximally pretreated patients to determine the potential use of PCSK9 inhibitors at various thresholds of total and LDL cholesterol levels.
Topics: Anticholesteremic Agents; Cardiovascular Diseases; Cholesterol, LDL; Cost-Benefit Analysis; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; PCSK9 Inhibitors; Practice Patterns, Physicians'; Secondary Prevention; United Kingdom | 2017 |
The need for a new classification of cholesterol lowering therapies.
Topics: Anticholesteremic Agents; Cholesterol; Cholesterol, LDL; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Universities | 2017 |
Safety of Alirocumab (A PCSK9 Monoclonal Antibody) from 14 Randomized Trials.
Topics: Acute Coronary Syndrome; Aged; Angina, Unstable; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Back Pain; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Comorbidity; Coronary Disease; Diabetes Mellitus, Type 2; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Influenza, Human; Middle Aged; Myocardial Infarction; Nasopharyngitis; Pruritus; Randomized Controlled Trials as Topic; Respiratory Tract Infections; Stroke; Urinary Tract Infections | 2016 |
Effect on Fasting Serum Glucose Levels of Adding Ezetimibe to Statins in Patients With Nondiabetic Hypercholesterolemia.
Topics: Aged; Anticholesteremic Agents; Apolipoproteins B; Blood Glucose; Cholesterol, HDL; Cholesterol, LDL; Comorbidity; Drug Therapy, Combination; Ezetimibe; Fasting; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperglycemia; Male; Metabolic Syndrome; Middle Aged; Randomized Controlled Trials as Topic; Simvastatin; Triglycerides | 2016 |
NKT Cell Hyporesponsiveness Leads to Unrestrained Accumulation of Marginal Zone B Cells in Hypercholesterolemic Apolipoprotein E-Deficient Mice.
Topics: Adoptive Transfer; Animals; Apolipoproteins E; B-Lymphocyte Subsets; B-Lymphocytes; Ezetimibe; Hypercholesterolemia; Interferon-gamma; Interleukin-4; Lymphoid Tissue; Mice; Mice, Inbred C57BL; Mice, Knockout; Natural Killer T-Cells | 2016 |
Ezetimibe: Use, costs, and adverse events in Australia.
Topics: Anticholesteremic Agents; Australia; Drug Costs; Drug Prescriptions; Drug Utilization Review; Drug-Related Side Effects and Adverse Reactions; Ezetimibe; Ezetimibe, Simvastatin Drug Combination; Humans; Hypercholesterolemia; Pharmacoepidemiology; Practice Patterns, Physicians'; Risk Factors; Time Factors; Treatment Outcome | 2017 |
Updates on prevention: obesity, ezetimibe, PCSK9, and HIV infection.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Body Mass Index; Cardiovascular Diseases; Cholesterol, LDL; Ezetimibe; HIV Infections; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipidemia, Familial Combined; Obesity; PCSK9 Inhibitors; Testosterone | 2016 |
The implications of the ezetimibe and simvastatin in hypercholesterolemia enhances atherosclerosis regression trial: a return to first principles.
Topics: Anticholesteremic Agents; Atherosclerosis; Azetidines; Cholesterol; Clinical Trials as Topic; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Simvastatin; Treatment Outcome | 2008 |
Efficacy of rosuvastatin (5 mg and 10 mg) twice a week in patients intolerant to daily statins.
Topics: Administration, Oral; Anticholesteremic Agents; Azetidines; Biological Products; Cholesterol, HDL; Cholesterol, LDL; Clofibric Acid; Dietary Supplements; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Drug Tolerance; Ezetimibe; Female; Fluorobenzenes; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pyrimidines; Retrospective Studies; Rosuvastatin Calcium; Sulfonamides; Treatment Outcome; Triglycerides | 2008 |
Is it over for ezetimibe?
Topics: Anticholesteremic Agents; Atherosclerosis; Azetidines; Controlled Clinical Trials as Topic; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Simvastatin | 2008 |
[Dual cholesterol inhibition. More high risk patients achieve LDL cholesterol values below 100 mg/dl].
Topics: Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol, LDL; Coronary Disease; Diabetic Angiopathies; Drug Therapy, Combination; Ezetimibe; Germany; Heptanoic Acids; Humans; Hypercholesterolemia; Multicenter Studies as Topic; Pyrroles; Randomized Controlled Trials as Topic; Simvastatin | 2008 |
Achieving target cholesterol levels in diabetic patients: potency of the statin or potency of the physician?
Topics: Aged; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Diabetes Mellitus; Dose-Response Relationship, Drug; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Israel; Male; Middle Aged; Patient Compliance | 2008 |
Is ezetimibe/simvastatin no better than simvastatin alone? Lessons learned and clinical implications.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Coronary Vessels; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Simvastatin; Tunica Intima | 2008 |
Given the ENHANCE trial results, ezetimibe is still unproven.
Topics: Azetidines; Cholesterol, LDL; Coronary Vessels; Evidence-Based Medicine; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Tunica Intima | 2008 |
Self-nanoemulsifying granules of ezetimibe: design, optimization and evaluation.
Topics: Animals; Anticholesteremic Agents; Azetidines; Biological Availability; Calorimetry, Differential Scanning; Capsules; Chemistry, Pharmaceutical; Cholesterol; Crystallography, X-Ray; Disease Models, Animal; Emulsions; Ezetimibe; Hydrogen-Ion Concentration; Hypercholesterolemia; Male; Microscopy, Electron, Scanning; Nanoparticles; Oils; Rats; Rats, Sprague-Dawley; Silicon Dioxide; Solubility; Surface-Active Agents | 2008 |
Statin plus ezetimibe treatment in clinical practice: the SI-SPECT (Slovenia (SI) Statin Plus Ezetimibe in Cholesterol Treatment) monitoring of clinical practice study.
Topics: Aged; Anticholesteremic Agents; Azetidines; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Monitoring, Physiologic | 2008 |
Recent news reports suggest that the cholesterol medicine Zetia doesn't work. Should I stop taking my prescription?
Topics: Anticholesteremic Agents; Azetidines; Ezetimibe; Humans; Hypercholesterolemia; Treatment Outcome | 2008 |
Ezetimibe revisited.
Topics: Anticholesteremic Agents; Aortic Valve Stenosis; Azetidines; Clinical Trials as Topic; Drug Combinations; Endpoint Determination; Ezetimibe; Humans; Hypercholesterolemia; Simvastatin | 2008 |
Ptosis, diplopia and statins: an association?
Topics: Adult; Atorvastatin; Autoantibodies; Autoimmune Diseases of the Nervous System; Azetidines; Blepharoptosis; Diabetes Complications; Diagnostic Errors; Diplopia; Eyelid Diseases; Ezetimibe; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Myasthenia Gravis; Myocardial Infarction; Pain; Pravastatin; Pyrroles; Receptors, Cholinergic; Recurrence; Strabismus | 2008 |
Serious drug-induced liver disease secondary to ezetimibe.
Topics: Anticholesteremic Agents; Azetidines; Chemical and Drug Induced Liver Injury; Ezetimibe; Female; Humans; Hypercholesterolemia; Middle Aged | 2008 |
Analyses of cancer data from three ezetimibe trials.
Topics: Anticholesteremic Agents; Aortic Valve Stenosis; Azetidines; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Follow-Up Studies; Humans; Hypercholesterolemia; Incidence; Neoplasms; Randomized Controlled Trials as Topic; Risk; Simvastatin | 2008 |
Hypercholesterolaemia: Clarifications from adverse drug reactions agency.
Topics: Anticholesteremic Agents; Azetidines; England; Ezetimibe; Humans; Hypercholesterolemia; Neoplasms; Risk Factors; Simvastatin; United States; United States Food and Drug Administration | 2008 |
After ENHANCE: the cholesterol hypothesis is alive and well.
Topics: Anticholesteremic Agents; Atherosclerosis; Azetidines; Ezetimibe; Humans; Hypercholesterolemia; Randomized Controlled Trials as Topic; Simvastatin; Tunica Intima; Tunica Media; Ultrasonography | 2008 |
Estimating the health benefits and costs associated with ezetimibe coadministered with statin therapy compared with higher dose statin monotherapy in patients with established cardiovascular disease: results of a Markov model for UK costs using data regis
Topics: Age Factors; Aged; Anticholesteremic Agents; Azetidines; Cardiovascular Diseases; Cost-Benefit Analysis; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoproteins, LDL; Male; Markov Chains; Middle Aged; Quality of Life; Quality-Adjusted Life Years; Risk Factors; Sex Factors; United Kingdom | 2008 |
Muddy waters: more stormy SEAS for ezetimibe.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Ezetimibe; Humans; Hypercholesterolemia; Treatment Outcome | 2008 |
Effectiveness of thrice weekly ezetimibe.
Topics: Aged; Anticholesteremic Agents; Azetidines; Cholesterol; Cholesterol, LDL; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Treatment Outcome | 2008 |
Effect of ezetimibe on plasma cholesterol levels, cholesterol absorption, and secretion of biliary cholesterol in laboratory opossums with high and low responses to dietary cholesterol.
Topics: Animals; Animals, Laboratory; Anticholesteremic Agents; Azetidines; Bile; Cholesterol; Cholesterol, Dietary; Diet, Atherogenic; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Ezetimibe; Gallbladder; Hypercholesterolemia; Opossums; Phenotype | 2008 |
The ENHANCE trial.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Coronary Artery Disease; Disease Progression; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Simvastatin | 2008 |
The ENHANCE trial.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Coronary Artery Disease; Disease Progression; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Simvastatin | 2008 |
Analyses of cancer data from three ezetimibe trials.
Topics: Anticholesteremic Agents; Azetidines; Data Interpretation, Statistical; Ezetimibe; Humans; Hypercholesterolemia; Neoplasms; Randomized Controlled Trials as Topic; Risk | 2009 |
Pooled analyses of effects on C-reactive protein and low density lipoprotein cholesterol in placebo-controlled trials of ezetimibe monotherapy or ezetimibe added to baseline statin therapy.
Topics: Anticholesteremic Agents; Azetidines; C-Reactive Protein; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Randomized Controlled Trials as Topic | 2009 |
Statins reduce the neurofibrillary tangle burden in a mouse model of tauopathy.
Topics: Animals; Atorvastatin; Azetidines; Brain; Capillary Permeability; Diet; Disease Models, Animal; Ezetimibe; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Immunohistochemistry; Maze Learning; Mice; Mice, Transgenic; Neurofibrillary Tangles; Pyrroles; Simvastatin; Spinal Cord; Tauopathies | 2009 |
Ezetimibe treatment of pediatric patients with hypercholesterolemia.
Topics: Adolescent; Anticholesteremic Agents; Azetidines; Child; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Ezetimibe; Female; Humans; Hypercholesterolemia; Hyperlipidemia, Familial Combined; Male; Triglycerides | 2009 |
Vascular lipid accumulation, lipoprotein oxidation, and macrophage lipid uptake in hypercholesterolemic zebrafish.
Topics: Age Factors; Aging; Animals; Animals, Genetically Modified; Anticholesteremic Agents; Atherosclerosis; Azetidines; Cell Line; Cholesterol, Dietary; Disease Models, Animal; Endothelium, Vascular; Ezetimibe; Female; Green Fluorescent Proteins; Humans; Hypercholesterolemia; Larva; Lipid Metabolism; Lipoproteins; Luminescent Proteins; Macrophages; Male; Mice; Microscopy, Confocal; Oxidation-Reduction; Permeability; Phospholipases A2; Time Factors; Toll-Like Receptor 4; Zebrafish | 2009 |
The g.-762T>C polymorphism of the NPC1L1 gene is common in Chinese and contributes to a higher promoter activity and higher serum cholesterol levels.
Topics: Asian People; Azetidines; China; Cholesterol; Demography; Ezetimibe; Female; Gene Frequency; Genotype; Hep G2 Cells; Humans; Hypercholesterolemia; Lovastatin; Male; Membrane Proteins; Membrane Transport Proteins; Middle Aged; Polymorphism, Single Nucleotide; Promoter Regions, Genetic | 2009 |
Safety and effectiveness of ezetimibe in liver transplant recipients with hypercholesterolemia.
Topics: Aged; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Immunosuppressive Agents; Liver Transplantation; Male; Middle Aged; Retrospective Studies; Time Factors; Treatment Outcome; Triglycerides | 2009 |
Utility of ezetimibe.
Topics: Anticholesteremic Agents; Azetidines; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Ezetimibe; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Male; Randomized Controlled Trials as Topic; Sensitivity and Specificity; Severity of Illness Index; Simvastatin; Treatment Outcome | 2009 |
What role for [black triangle down] colesevelam in cardiovascular prevention?
Topics: Allylamine; Anticholesteremic Agents; Azetidines; Cardiovascular Diseases; Colesevelam Hydrochloride; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Treatment Outcome | 2009 |
Regulation of steroid 5-alpha reductase type 2 (Srd5a2) by sterol regulatory element binding proteins and statin.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Animals; Atorvastatin; Azetidines; Cell Line, Tumor; Ezetimibe; Gene Expression Regulation, Enzymologic; Heptanoic Acids; Hydroxymethylglutaryl CoA Reductases; Hypercholesterolemia; Liver; Lovastatin; Male; Mice; Promoter Regions, Genetic; Prostate; Prostatic Neoplasms; Pyrroles; Sterol Regulatory Element Binding Protein 2; Transfection | 2009 |
Premature release of data from clinical trials of ezetimibe.
Topics: Adverse Drug Reaction Reporting Systems; Anticholesteremic Agents; Azetidines; Cardiovascular Diseases; Cholesterol, LDL; Databases as Topic; Drug Approval; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Incidence; Neoplasms; Randomized Controlled Trials as Topic; Registries; Simvastatin; United States | 2009 |
Drugs for children with hypercholesterolemia: be cautious.
Topics: Anticholesteremic Agents; Azetidines; Child; Cholesterol, LDL; Contraindications; Ezetimibe; Humans; Hypercholesterolemia; Treatment Outcome | 2009 |
Clinical experience with ezetimibe/simvastatin in a Mediterranean population.
Topics: Aged; Anticholesteremic Agents; Azetidines; Drug Therapy, Combination; Ezetimibe; Female; Greece; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Male; Middle Aged; Prospective Studies; Simvastatin | 2009 |
Effects of ezetimibe add-on therapy for high-risk patients with dyslipidemia.
Topics: Aged; Anticholesteremic Agents; Apolipoprotein A-I; Apolipoproteins B; Azetidines; Cholesterol, HDL; Cholesterol, LDL; Dyslipidemias; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Prospective Studies | 2009 |
[Effectiveness of ezetimibe in improving lipid goal attainment in patients with coronary heart diseases treated with statin].
Topics: Alanine Transaminase; Anticholesteremic Agents; Aspartate Aminotransferases; Azetidines; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Creatine Kinase; Diabetes Complications; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Treatment Outcome; Triglycerides | 2009 |
Cholesterol drug lowers LDL-C levels but again fails to show clinical benefit.
Topics: Anticholesteremic Agents; Azetidines; Cardiovascular Diseases; Carotid Arteries; Cholesterol, LDL; Clinical Trials as Topic; Drug Approval; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Niacin; Practice Patterns, Physicians'; Risk Factors; Simvastatin; Treatment Outcome; Ultrasonography; United States; United States Food and Drug Administration | 2010 |
Efficacy of simvastatin or ezetimibe on tissue factor, von Willebrand's factor and C-reactive protein in patients with hypercholesterolaemia.
Topics: Adult; Aged; Anticholesteremic Agents; Azetidines; Biomarkers; C-Reactive Protein; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Male; Middle Aged; Simvastatin; Thromboplastin; Time Factors; Treatment Outcome; von Willebrand Factor | 2010 |
Ezetimibe ameliorates metabolic disorders and microalbuminuria in patients with hypercholesterolemia.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Albuminuria; Anticholesteremic Agents; Azetidines; C-Reactive Protein; Case-Control Studies; Cholesterol, LDL; Deoxyguanosine; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Metabolic Diseases; Metabolic Syndrome; Middle Aged; Nitrates; Nitrites; Oxidative Stress; Tumor Necrosis Factor-alpha | 2010 |
Ezetimibe and recent clinical trials: a look on the bright side.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Delayed-Action Preparations; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Niacin; Placebos; Randomized Controlled Trials as Topic; Simvastatin; Treatment Outcome; Triglycerides | 2010 |
Retrospective, observation study: Quantitative and qualitative effect of ezetimibe and HMG-CoA reductase inhibitors on LDL-cholesterol: are there disappearance thresholds for small, dense LDL and IDL?
Topics: Aged; Azetidines; Cholesterol, LDL; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoproteins, IDL; Lipoproteins, LDL; Male; Middle Aged; Retrospective Studies | 2010 |
Ezetimibe. The French authorities gradually confirm the lack of benefit.
Topics: Anticholesteremic Agents; Azetidines; Ezetimibe; Humans; Hypercholesterolemia | 2010 |
[The current debate on lowering LDL cholesterol with ezetimibe].
Topics: Anticholesteremic Agents; Azetidines; Cardiovascular Diseases; Cholesterol, LDL; Ezetimibe; Humans; Hypercholesterolemia | 2010 |
Ask the doctor. I have tried all of the statin drugs to lower my cholesterol, but each one has caused severe muscle pain. Are there any non-statin medications I could try using to lower my cholesterol?
Topics: Allylamine; Azetidines; Colesevelam Hydrochloride; Diet, Mediterranean; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Muscular Diseases; Niacin; Pain; Sitosterols | 2010 |
Managing residual risk in patients receiving statin therapy.
Topics: Anticholesteremic Agents; Atherosclerosis; Azetidines; Cholesterol, LDL; Ezetimibe; Humans; Hypercholesterolemia; Simvastatin | 2010 |
Effects of lipid-lowering drugs on reverse cholesterol transport gene expressions in peripheral blood mononuclear and HepG2 cells.
Topics: Absorption; Anticholesteremic Agents; Atorvastatin; ATP-Binding Cassette Transporters; Azetidines; Biological Transport; Cholesterol; Dose-Response Relationship, Drug; Down-Regulation; Drug Therapy, Combination; Ezetimibe; Female; Gene Expression; Hep G2 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Leukocytes, Mononuclear; Lipid Metabolism; Male; Middle Aged; Orphan Nuclear Receptors; Pyrroles; RNA, Messenger; Simvastatin; Up-Regulation | 2010 |
Nanocarrier for the enhanced bioavailability of a cardiovascular agent: in vitro, pharmacodynamic, pharmacokinetic and stability assessment.
Topics: Animals; Anticholesteremic Agents; Azetidines; Biological Availability; Cardiovascular Agents; Cholesterol; Drug Carriers; Drug Stability; Drug Storage; Emulsions; Ezetimibe; Hypercholesterolemia; Microscopy, Electron, Transmission; Nanostructures; Particle Size; Rats; Rats, Wistar; Solubility; Surface Properties | 2011 |
[On the current debate on lowering LDL cholesterol with ezetimibe].
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Coronary Artery Disease; Evidence-Based Medicine; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Randomized Controlled Trials as Topic; Simvastatin | 2010 |
Emphasizing the burden of proof: The American College of Cardiology 2008 Expert Panel Comments on the ENHANCE Trial.
Topics: Anticholesteremic Agents; Atherosclerosis; Azetidines; Biomarkers; Cardiology; Carotid Arteries; Clinical Trials as Topic; Clinical Trials Data Monitoring Committees; Evidence-Based Medicine; Expert Testimony; Ezetimibe; Humans; Hypercholesterolemia; Lipoproteins, LDL; Simvastatin | 2010 |
Ezetimibe, an inhibitor of intestinal cholesterol absorption, decreases serum level of malondialdehyde-modified low-density lipoprotein in patients with hypercholesterolemia.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol; Ezetimibe; Female; Humans; Hypercholesterolemia; Intestinal Absorption; Lipoproteins, LDL; Male; Middle Aged | 2011 |
Achieving optimal lipid goals in patients with coronary artery disease.
Topics: Aged; Anticholesteremic Agents; Azetidines; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Logistic Models; Male; Practice Patterns, Physicians'; Sex Factors; Triglycerides | 2011 |
Improved efficacy for ezetimibe and rosuvastatin by attenuating the induction of PCSK9.
Topics: Animals; Anticholesteremic Agents; Apolipoproteins B; Azetidines; Cholesterol; Cholesterol, LDL; Enzyme-Linked Immunosorbent Assay; Ezetimibe; Fluorobenzenes; Hypercholesterolemia; Mice; Mice, Inbred C57BL; Proprotein Convertase 9; Proprotein Convertases; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Rosuvastatin Calcium; Serine Endopeptidases; Sulfonamides; Triglycerides | 2011 |
Ezetimibe and low density lipoprotein subfractions: an ongoing debate.
Topics: Anticholesteremic Agents; Azetidines; Chemical Fractionation; Cholesterol; Cholesterol, LDL; Dissent and Disputes; Ezetimibe; Humans; Hypercholesterolemia; Lipoproteins, LDL; Particle Size; Prognosis; Simvastatin | 2011 |
Lipid-altering efficacy and safety profile of combination therapy with ezetimibe/statin vs. statin monotherapy in patients with and without diabetes: an analysis of pooled data from 27 clinical trials.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Azetidines; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Randomized Controlled Trials as Topic; Simvastatin; Treatment Outcome; Young Adult | 2011 |
Effects of currently prescribed LDL-C-lowering drugs on PCSK9 and implications for the next generation of LDL-C-lowering agents.
Topics: Animals; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Ezetimibe; Fenofibrate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Proprotein Convertase 9; Proprotein Convertases; Serine Endopeptidases | 2011 |
Influence of polymorphisms and cholesterol-lowering treatment on SCARB1 mRNA expression.
Topics: Adult; Aged; Anticholesteremic Agents; Atorvastatin; Azetidines; Caco-2 Cells; DNA; Ezetimibe; Female; Hep G2 Cells; Heptanoic Acids; Humans; Hypercholesterolemia; Leukocytes, Mononuclear; Lipids; Male; Middle Aged; Polymorphism, Genetic; Pyrroles; RNA, Messenger; Scavenger Receptors, Class B; Simvastatin | 2011 |
Statin-associated myasthenic weakness.
Topics: Anticholesteremic Agents; Azetidines; Cholinesterase Inhibitors; Electromyography; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Middle Aged; Muscle Weakness; Myasthenia Gravis; Simvastatin; Treatment Outcome | 2011 |
[After bypass surgery nearly all lipids are in the normal range. However, Lp(a) is too high, what can be done?].
Topics: Azetidines; Cholesterol; Coronary Artery Bypass; Coronary Artery Disease; Drug Therapy, Combination; Ezetimibe; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hypercholesterolemia; Hypolipidemic Agents; Indoles; Lipoprotein(a); Male; Postoperative Complications; Prognosis; Reference Values; Risk Factors; Secondary Prevention; Treatment Outcome | 2011 |
Nitroxide derivatives for imaging of hypercholesterolemia-induced kidney dysfunction and assessing the effectiveness of antilipidemic drugs.
Topics: Animals; Anticholesteremic Agents; Azetidines; Cholesterol; Cholesterol, Dietary; Cholestyramine Resin; Contrast Media; Cyclic N-Oxides; Drug Monitoring; Ezetimibe; Gadolinium DTPA; Humans; Hypercholesterolemia; Kidney; Kinetics; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Nitrogen Oxides; Pyrrolidines; Renal Insufficiency | 2011 |
Do functional foods have a role in the prevention of cardiovascular disease?
Topics: Anticholesteremic Agents; Azetidines; Blood Pressure; Cholesterol, Dietary; Dietary Proteins; Ezetimibe; Female; Humans; Hypercholesterolemia; Hypertension; Lipid Metabolism; Male; Milk Proteins; Phytosterols; Soybean Proteins | 2011 |
Retrospective study on antihyperlipidemic efficacy and safety of simvastatin, ezetimibe and their combination in Korean adults.
Topics: Adult; Aged; Asian People; Azetidines; Cholesterol; Cholesterol, LDL; Coronary Disease; Drug Combinations; Drug Synergism; Ezetimibe; Ezetimibe, Simvastatin Drug Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Korea; Male; Middle Aged; Retrospective Studies; Risk Factors; Simvastatin; Treatment Outcome; Triglycerides | 2011 |
Ezetimibe monotherapy ameliorates vascular function in patients with hypercholesterolemia through decreasing oxidative stress.
Topics: Aged; Azetidines; Case-Control Studies; Endothelium, Vascular; Ezetimibe; Humans; Hypercholesterolemia; Lipids; Male; Middle Aged; Oxidative Stress | 2011 |
[Elevated augmentation index].
Topics: Anticholesteremic Agents; Antihypertensive Agents; Azetidines; Bisoprolol; Blood Pressure; Carbazoles; Carvedilol; Drug Costs; Drug Substitution; Evidence-Based Medicine; Ezetimibe; Female; Germany; Humans; Hypercholesterolemia; Hypertension; Male; Middle Aged; Propanolamines; Pulse | 2012 |
Ezetimibe ameliorates atherosclerotic and inflammatory markers, atherogenic lipid profiles, insulin sensitivity, and liver dysfunction in Japanese patients with hypercholesterolemia.
Topics: Administration, Oral; Anticholesteremic Agents; Asian People; Atherosclerosis; Azetidines; Biomarkers; Case-Control Studies; Ezetimibe; Female; Humans; Hypercholesterolemia; Inflammation; Insulin Resistance; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Liver Diseases; Male; Matrix Metalloproteinase 9; Middle Aged; Prognosis; Prospective Studies; Vascular Cell Adhesion Molecule-1 | 2012 |
[Achievement of therapeutic target in subjects on statin treatment in clinical practice. Results of the STAR (Statins Target Assessment in Real practice) study].
Topics: Aged; Algorithms; Azetidines; Biomarkers; Cardiovascular Diseases; Cerebrovascular Disorders; Cholesterol, LDL; Cohort Studies; Diabetes Complications; Diabetes Mellitus; Ezetimibe; Female; Fluorobenzenes; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Italy; Lovastatin; Male; Medication Adherence; Middle Aged; Pravastatin; Pyrimidines; Retrospective Studies; Risk Assessment; Risk Factors; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Treatment Outcome | 2011 |
Ezetimibe reduces urinary albumin excretion in hypercholesterolaemic type 2 diabetes patients with microalbuminuria.
Topics: Albumins; Albuminuria; Azetidines; Blood Pressure; Body Mass Index; Chemokine CCL2; Cholesterol, LDL; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Ezetimibe; Female; Glycated Hemoglobin; Humans; Hypercholesterolemia; Male; Middle Aged; Triglycerides | 2012 |
[The influence of ezetimibe and simvaststin on platelet aggregation and protein c system in patients with coronary heart disease and hypercholesterolemia].
Topics: Anticholesteremic Agents; Azetidines; Coronary Disease; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Platelet Aggregation; Protein C; Simvastatin | 2012 |
Optimized self nano-emulsifying systems of ezetimibe with enhanced bioavailability potential using long chain and medium chain triglycerides.
Topics: Algorithms; Animals; Anticholesteremic Agents; Azetidines; Biological Availability; Diet, High-Fat; Drug Carriers; Drug Stability; Emulsifying Agents; Ezetimibe; Female; Glycerides; Hypercholesterolemia; Intestinal Absorption; Lipoproteins, HDL; Lipoproteins, LDL; Microscopy, Electron, Transmission; Nanoparticles; Organic Chemicals; Rats; Rats, Sprague-Dawley; Thermodynamics; Triglycerides | 2012 |
Efficacy of ezetimibe is associated with gender and baseline lipid levels in patients with type 2 diabetes.
Topics: Aged; Azetidines; Body Mass Index; Cholesterol; Cholesterol, LDL; Diabetes Mellitus, Type 2; Ezetimibe; Female; Glycated Hemoglobin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Male; Middle Aged; Sex Factors; Triglycerides | 2012 |
Meta-analysis methods and models with applications in evaluation of cholesterol-lowering drugs.
Topics: Analysis of Variance; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Computer Simulation; Drug Therapy, Combination; Endpoint Determination; Evaluation Studies as Topic; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Likelihood Functions; Lipoproteins, HDL; Meta-Analysis as Topic; Multivariate Analysis; Randomized Controlled Trials as Topic; Research Design | 2012 |
Effect of ezetimibe on insulin secretion in db/db diabetic mice.
Topics: Animals; Anticholesteremic Agents; Azetidines; Diabetes Complications; Diabetes Mellitus, Type 2; Ezetimibe; Glucose Intolerance; Hypercholesterolemia; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Kinetics; Male; Mice; Mice, Congenic; Mice, Mutant Strains; Random Allocation; Specific Pathogen-Free Organisms | 2012 |
Into the future: diversifying lipid management.
Topics: Antibodies, Monoclonal; Anticholesteremic Agents; Azetidines; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Proprotein Convertase 9; Proprotein Convertases; Serine Endopeptidases | 2012 |
[The SHARP study].
Topics: Anticholesteremic Agents; Azetidines; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Kidney Failure, Chronic; Randomized Controlled Trials as Topic; Simvastatin | 2013 |
[Lipid control in the double pack. Combined drugs to achieve the goal].
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia | 2002 |
[Ezetimib. A new cholesterol absorption inhibitor].
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, Dietary; Clinical Trials as Topic; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Intestinal Absorption | 2002 |
[Statins plus cholesterol resorption inhibitor. LDL goal values attainable].
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestinal Absorption; Simvastatin; Treatment Outcome | 2002 |
Ezetimibe in hypercholesterolaemia.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Treatment Outcome | 2002 |
Atherosclerosis: cell biology and lipoproteins: cholesterol absorption inhibitors: gateway therapy for hypercholesterolaemia.
Topics: Animals; Anticholesteremic Agents; Arteriosclerosis; Azetidines; Cholesterol; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestinal Absorption; Lipoproteins | 2002 |
[Ezetimib plus statin combination. A strong duo].
Topics: Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol; Coronary Disease; Drug Therapy, Combination; Ezetimibe; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Pyrroles; Risk Factors; Simvastatin | 2002 |
[Cholesterol resorption inhibition prevents high statin doses. Lipid lowering in double-pack].
Topics: Adult; Aged; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hypercholesterolemia; Hypolipidemic Agents; Male; Placebos; Randomized Controlled Trials as Topic; Risk Factors | 2002 |
[Lowering cholesterol becomes easier. Combining instead of increasing dosage].
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Clinical Trials as Topic; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Simvastatin | 2003 |
Combined lipid lowering drug therapy for the effective treatment of hypercholesterolaemia.
Topics: Azetidines; Cholesterol; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Hypolipidemic Agents; Intestinal Absorption | 2003 |
Ezetimibe potently inhibits cholesterol absorption but does not affect acute hepatic or intestinal cholesterol synthesis in rats.
Topics: Animals; Anticholesteremic Agents; Azetidines; Cholesterol; Dose-Response Relationship, Drug; Ezetimibe; Hypercholesterolemia; Intestinal Absorption; Liver; Male; Rats; Rats, Sprague-Dawley | 2003 |
New lipid-lowering combo proves successful.
Topics: Atorvastatin; Attitude to Health; Azetidines; Drug Synergism; Drug Therapy, Combination; Europe; Ezetimibe; Heptanoic Acids; Humans; Hypercholesterolemia; Hypertension; Pyrroles; Stroke; Treatment Outcome | 2003 |
Efficacy of simvastatin and ezetimibe in treating hypercholesterolemia.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Simvastatin; Treatment Outcome | 2003 |
Ezetimibe for hypercholesterolemia.
Topics: Anticholesteremic Agents; Azetidines; Ezetimibe; Humans; Hypercholesterolemia | 2003 |
[Ezetimib as combination partner in hypercholesteremia. Lowering LDL beyond the effect of statins].
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia | 2003 |
Therapy and clinical trials: ezetimibe.
Topics: Animals; Anticholesteremic Agents; Apolipoproteins E; Arteriosclerosis; Azetidines; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestinal Absorption; Mice; Mice, Knockout; Triglycerides | 2003 |
Ezetimibe: a new addition to lipid-lowering therapy.
Topics: Anticholesteremic Agents; Azetidines; Coronary Artery Disease; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia | 2003 |
Effectiveness of ezetimibe in clinical practice.
Topics: Aged; Anticholesteremic Agents; Azetidines; Cholesterol; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Outpatient Clinics, Hospital; Retrospective Studies; Treatment Outcome; Triglycerides | 2004 |
Stenosis and the drug-eluting stent.
Topics: Angiotensin-Converting Enzyme Inhibitors; Anticholesteremic Agents; Azetidines; Cardiology; Coronary Restenosis; Diabetes Complications; Ezetimibe; Humans; Hypercholesterolemia; Myocardial Infarction; Myocardial Ischemia; Perindopril; Radionuclide Imaging; Randomized Controlled Trials as Topic; Stents | 2004 |
Homozygous hypercholesterolaemia and ezetimibe: a case report.
Topics: Anticholesteremic Agents; Azetidines; Child; Cholesterol, LDL; Ezetimibe; Female; Homozygote; Humans; Hypercholesterolemia; LDL-Receptor Related Proteins; Point Mutation; Receptors, LDL | 2004 |
On call. I'm a 63-year-old man with arthritis but no other conditions. My only medicines were Naprosyn and vitamins until my last annual checkup, when my cholesterol was high. My doctor gave me Zocor, which helped. But I developed muscle aches, so he swit
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, HDL; Cholesterol, LDL; Ezetimibe; Humans; Hypercholesterolemia; Male; Middle Aged; Reference Values; Simvastatin | 2004 |
[Ezetimibe (Ezetrol)].
Topics: Anticholesteremic Agents; Azetidines; Cardiovascular Diseases; Cholesterol; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Phytosterols; Treatment Outcome | 2004 |
[Recommended LDL value far lower. How does one achieve this goal?].
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Clinical Trials as Topic; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Reference Values | 2004 |
Safety and tolerability of ezetimibe.
Topics: Azetidines; Drug Tolerance; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia | 2004 |
[New combination therapy. Up to 60% lower LDL cholesterol level].
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Coronary Disease; Drug Combinations; Drug Synergism; Ezetimibe; Humans; Hypercholesterolemia; Simvastatin | 2004 |
Vytorin: a combination of ezetimibe and simvastatin.
Topics: Azetidines; Dose-Response Relationship, Drug; Drug Combinations; Ezetimibe; Ezetimibe, Simvastatin Drug Combination; Humans; Hypercholesterolemia; Simvastatin; Treatment Outcome | 2004 |
Ezetimibe--a new cholesterol-lowering drug.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Drug Costs; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Randomized Controlled Trials as Topic; Treatment Outcome | 2004 |
Effectiveness and tolerability of ezetimibe add-on therapy to a bile acid resin-based regimen for hypercholesterolemia.
Topics: Allylamine; Anticholesteremic Agents; Azetidines; Cholestyramine Resin; Colesevelam Hydrochloride; Colestipol; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Prospective Studies; Treatment Outcome | 2004 |
[Ezetimib--a new possibility for combined therapy in hypercholesterolemia].
Topics: Anticholesteremic Agents; Azetidines; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia | 2004 |
Effect of high plant sterol-enriched diet and cholesterol absorption inhibitor, SCH 58235, on plant sterol absorption and plasma concentrations in hypercholesterolemic wild-type Kyoto rats.
Topics: Animals; Azetidines; Cholesterol; Diet; Ezetimibe; Hydroxymethylglutaryl CoA Reductases; Hypercholesterolemia; Intestinal Absorption; Male; Phytosterols; Rats; Rats, Inbred WKY; Rats, Wistar; Species Specificity | 2005 |
[Target values are more often attainable. Almost doubly so many patients with values under 100mg/dl].
Topics: Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol, LDL; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Heptanoic Acids; Humans; Hypercholesterolemia; Pyrroles; Randomized Controlled Trials as Topic; Reference Values; Simvastatin; Time Factors | 2004 |
Lipid-lowering drugs.
Topics: Anticholesteremic Agents; Azetidines; Cholestyramine Resin; Coronary Disease; Ezetimibe; Fatty Acids, Omega-3; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Niacin; Risk Factors; Treatment Outcome | 2004 |
Consistency in efficacy and safety of ezetimibe coadministered with statins for treatment of hypercholesterolemia in women and men.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Sex Factors; Simvastatin; Time Factors; Treatment Outcome; Women's Health | 2004 |
Development and validation of a model to project the long-term benefit and cost of alternative lipid-lowering strategies in patients with hypercholesterolaemia.
Topics: Anticholesteremic Agents; Azetidines; Clinical Trials as Topic; Coronary Disease; Cost Control; Cost-Benefit Analysis; Disease Progression; Dose-Response Relationship, Drug; Drug Costs; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Models, Economic; Reproducibility of Results; Time Factors | 2004 |
Cost-effectiveness of ezetimibe coadministration in statin-treated patients not at cholesterol goal: application to Germany, Spain and Norway.
Topics: Anticholesteremic Agents; Azetidines; Coronary Disease; Cost-Benefit Analysis; Decision Support Techniques; Dose-Response Relationship, Drug; Drug Costs; Drug Therapy, Combination; Ezetimibe; Female; Germany; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Male; Middle Aged; Norway; Risk Factors; Spain | 2004 |
[Coronary heart disease patient reaches LDL level of 100 mg/dl with atorvastatin: how do you continue treatment next year?].
Topics: Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol, LDL; Coronary Artery Disease; Cost Control; Drug Costs; Ezetimibe; Germany; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Insurance Coverage; Male; Middle Aged; National Health Programs; Pyrroles; Simvastatin | 2004 |
[New therapeutic alternative to aggressive statin treatment].
Topics: Anticholesteremic Agents; Azetidines; Ezetimibe; Humans; Hypercholesterolemia | 2005 |
[Ezetimibe].
Topics: Anticholesteremic Agents; Azetidines; Drug Monitoring; Ezetimibe; Humans; Hypercholesterolemia; Nurse's Role; Patient Education as Topic; Patient Selection; Treatment Outcome | 2005 |
Getting there: statin plus ezetimibe for low-density lipoprotein cholesterol goals.
Topics: Adult; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Practice Guidelines as Topic | 2005 |
Development and validation of a reversed-phase HPLC method for the determination of ezetimibe in pharmaceutical dosage forms.
Topics: Acetonitriles; Anticholesteremic Agents; Azetidines; Calibration; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Industry; Drug Stability; Enterocytes; Ezetimibe; Heptanes; Hydrogen-Ion Concentration; Hypercholesterolemia; Models, Chemical; Pharmaceutical Preparations; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Sulfonic Acids; Tablets; Temperature; Time Factors; Ultraviolet Rays | 2005 |
The use of ezetimibe in achieving low density lipoprotein lowering goals in clinical practice: position statement of a United Kingdom consensus panel.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Consensus; Ezetimibe; Humans; Hypercholesterolemia; Practice Guidelines as Topic; United Kingdom | 2005 |
[Lowering LDL cholesterol frequently does not adhere to guidelines. Also regard intestinal cholesterol source].
Topics: Anticholesteremic Agents; Azetidines; Cardiovascular Diseases; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Guideline Adherence; Humans; Hypercholesterolemia; Intestinal Mucosa; Intestines; Liver; Reference Values; Simvastatin | 2005 |
[Ezetimib and simvastatin. Cooperation at receptors of cholesterol metabolism].
Topics: Adult; Azetidines; Cardiovascular Diseases; Cholesterol, LDL; Drug Synergism; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Hypolipidemic Agents; Multicenter Studies as Topic; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Simvastatin; Treatment Outcome | 2005 |
[Goal in hypercholesterolemia: lowering LDL cholesterol level by 50%].
Topics: Azetidines; Cholesterol, LDL; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Hypolipidemic Agents; Randomized Controlled Trials as Topic; Simvastatin | 2005 |
NPC1L1 haplotype is associated with inter-individual variation in plasma low-density lipoprotein response to ezetimibe.
Topics: Adult; Aged; Azetidines; Cholesterol, LDL; Ezetimibe; Female; Gene Frequency; Genetic Variation; Haplotypes; Humans; Hypercholesterolemia; Male; Membrane Proteins; Membrane Transport Proteins; Middle Aged; Polymorphism, Single Nucleotide; Proteins | 2005 |
Drug-induced acute autoimmune hepatitis during combination therapy with atorvastatin and ezetimibe.
Topics: Anticholesteremic Agents; Atorvastatin; Azetidines; Drug Therapy, Combination; Ezetimibe; Female; Hepatitis, Autoimmune; Heptanoic Acids; Humans; Hypercholesterolemia; Liver Function Tests; Middle Aged; Pyrroles | 2005 |
Therapy and clinical trials.
Topics: Anticholesteremic Agents; Atherosclerosis; Azetidines; Clinical Trials as Topic; Ezetimibe; Humans; Hypercholesterolemia; Simvastatin | 2005 |
[Ezetimibe--pharmacokinetics and therapeutics].
Topics: Anticholesteremic Agents; Azetidines; Drug Interactions; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia | 2005 |
Effect of ezetimibe on the in vivo kinetics of apoB-48 and apoB-100 in men with primary hypercholesterolemia.
Topics: Adult; Anticholesteremic Agents; Apolipoprotein B-100; Apolipoprotein B-48; Apolipoproteins B; Azetidines; Cholesterol, LDL; Ezetimibe; Humans; Hypercholesterolemia; Lipoproteins; Lipoproteins, IDL; Lipoproteins, VLDL; Male; Middle Aged | 2006 |
Ezetimibe in renal transplant patients with hyperlipidemia resistant to HMG-CoA reductase inhibitors.
Topics: Adult; Aged; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Drug Resistance; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Kidney Transplantation; Male; Middle Aged; Retrospective Studies; Treatment Outcome; Triglycerides | 2006 |
Selective compensatory induction of hepatic HMG-CoA reductase in response to inhibition of cholesterol absorption.
Topics: Animals; Anticholesteremic Agents; Azetidines; Cholesterol; Cholesterol, Dietary; Diabetes Mellitus, Type 1; Enzyme Induction; Ezetimibe; Hydroxymethylglutaryl CoA Reductases; Hypercholesterolemia; Liver; Male; Rats; Rats, Sprague-Dawley; Receptors, LDL; Thyroid Hormones; Thyroidectomy; Transcription, Genetic | 2006 |
Drug utilization of ezetimibe in rehabilitation centres: registry analysis of factors influencing prescription and effectiveness of treatment.
Topics: Aged; Anticholesteremic Agents; Azetidines; Drug Utilization Review; Ezetimibe; Female; Germany; Humans; Hypercholesterolemia; Male; Middle Aged; Practice Patterns, Physicians'; Registries; Rehabilitation Centers; Treatment Outcome | 2006 |
Lower cholesterol without statins. Options are available.
Topics: Allylamine; Azetidines; Cholesterol, LDL; Cholinergic Antagonists; Colesevelam Hydrochloride; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Niacin; Phytosterols | 2006 |
Severe hepatic side effects of ezetimibe.
Topics: Anticholesteremic Agents; Atorvastatin; Azetidines; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Ezetimibe; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Liver Diseases; Male; Middle Aged; Pyrroles; Transaminases | 2006 |
Total and low-density lipoprotein cholesterol responses to ezetimibe in clinical practice.
Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Azetidines; Cholesterol; Ezetimibe; Female; Humans; Hypercholesterolemia; Male; Medical Audit; Middle Aged; Retrospective Studies; Treatment Outcome | 2006 |
Cost effectiveness of adding ezetimibe to atorvastatin therapy in patients not at cholesterol treatment goal in Canada.
Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol, HDL; Cholesterol, LDL; Cost-Benefit Analysis; Drug Costs; Ezetimibe; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Pyrroles | 2006 |
[Horse and rider].
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Ezetimibe; Heart Diseases; Humans; Hypercholesterolemia; Risk Factors | 2006 |
Intensive lipid-lowering therapy: obvious benefits, possible risks.
Topics: Aged, 80 and over; Azetidines; Coronary Disease; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Muscular Diseases | 2006 |
Treatment of hypercholesterolemia with ezetimibe in cardiac transplant recipients.
Topics: Adult; Aged; Anticholesteremic Agents; Azetidines; Ezetimibe; Female; Heart Transplantation; Humans; Hypercholesterolemia; Lipoproteins; Lipoproteins, LDL; Male; Middle Aged; Muscular Diseases; Pain | 2007 |
Lipid-lowering therapy--benefits and risks.
Topics: Azetidines; Coronary Disease; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Muscular Diseases; Risk Factors | 2007 |
Lipid-lowering therapy--benefits and risks.
Topics: Aged, 80 and over; Azetidines; Coronary Disease; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Muscular Diseases; Risk Factors | 2007 |
[Synthesis plus absorption inhibitors are useful for high risk patients].
Topics: Anticholesteremic Agents; Azetidines; Cholesterol; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Intestinal Absorption; Risk | 2007 |
[Molecular diagnosis and combined lipid lowering therapy of heterozygous familial hypercholesterolemia. Report of one case].
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Ezetimibe; Female; Heterozygote; Humans; Hypercholesterolemia; LDL-Receptor Related Proteins; Middle Aged; Mutation; Oligonucleotide Array Sequence Analysis; Prognosis; Simvastatin | 2007 |
Age-induced hypercholesterolemia in the rat relates to reduced elimination but not increased intestinal absorption of cholesterol.
Topics: Aging; Animals; Anticholesteremic Agents; Azetidines; Bile Acids and Salts; Cholesterol; Ezetimibe; Growth Hormone; Hypercholesterolemia; Intestinal Absorption; Male; Rats; Rats, Wistar; Treatment Outcome | 2007 |
Therapy and clinical trials.
Topics: Acquired Immunodeficiency Syndrome; Atherosclerosis; Azetidines; Cholesterol, LDL; Clinical Trials as Topic; Ezetimibe; Humans; Hypercholesterolemia; Metabolic Syndrome; Models, Biological; Obesity; Risk Factors | 2007 |
[Statin and absorption inhibitor work synergistically. More risk patient reach LDL cholesterol goal value].
Topics: Anticholesteremic Agents; Azetidines; Cardiovascular Diseases; Cholesterol, LDL; Clinical Trials as Topic; Drug Synergism; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Infant, Newborn; Practice Guidelines as Topic; Simvastatin; Treatment Outcome | 2007 |
Effect of ezetimibe in patients who cannot tolerate statins or cannot get to the low density lipoprotein cholesterol target despite taking a statin.
Topics: Aged; Anticholesteremic Agents; Azetidines; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Retrospective Studies | 2007 |
Ezetimibe in search of receptor(s)--still a never-ending challenge in cholesterol absorption and transport.
Topics: Animals; Anticholesteremic Agents; Azetidines; Biological Transport; Cell Line; Cell Membrane; Ezetimibe; Humans; Hypercholesterolemia; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Transport Vesicles | 2007 |
[Type 1 diabetes: what are the alternatives for lowering cholesterol levels with statins?].
Topics: Anticholesteremic Agents; Azetidines; Diabetes Mellitus, Type 1; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Middle Aged; Rhabdomyolysis | 2007 |
Inhibition of intestinal absorption of cholesterol by ezetimibe or bile acids by SC-435 alters lipoprotein metabolism and extends the lifespan of SR-BI/apoE double knockout mice.
Topics: Animals; Anticholesteremic Agents; Apolipoproteins E; Azetidines; Bile Acids and Salts; Body Weight; Cardiomegaly; Cholesterol; Coronary Artery Disease; Cyclic N-Oxides; Disease Models, Animal; Eating; Ezetimibe; Female; Fibrosis; Hypercholesterolemia; Intestinal Absorption; Life Expectancy; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Scavenger Receptors, Class B; Survival Rate; Triglycerides; Tropanes | 2008 |
Ezetimibe's effect on platelet aggregation and LDL tendency to peroxidation in hypercholesterolaemia as monotherapy or in addition to simvastatin.
Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Azetidines; Case-Control Studies; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hypercholesterolemia; Lipid Peroxidation; Male; Middle Aged; Oxidative Stress; Platelet Aggregation; Simvastatin; Treatment Outcome | 2008 |
Help for your cholesterol when statins won't do. If you are one of the many, but also one of the few...
Topics: Anticholesteremic Agents; Azetidines; Clofibric Acid; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Life Style; Male; Niacin | 2005 |
Enhanced LDL-C reduction: lower is better. Does it matter how?
Topics: Anticholesteremic Agents; Azetidines; Cardiovascular Diseases; Cholesterol, LDL; Ezetimibe; Humans; Hypercholesterolemia | 2008 |
Lipid-lowering study raises issues of therapy's value.
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Drug Combinations; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Simvastatin | 2008 |
Use of ezetimibe in the United States and Canada.
Topics: Anticholesteremic Agents; Azetidines; Canada; Cholesterol, LDL; Cohort Studies; Drug Utilization; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Practice Patterns, Physicians'; United States | 2008 |
Dramatically increased intestinal absorption of cholesterol following hypophysectomy is normalized by thyroid hormone.
Topics: Animals; Anti-Inflammatory Agents; Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 5; ATP Binding Cassette Transporter, Subfamily G, Member 8; ATP-Binding Cassette Transporters; Azetidines; Cholesterol; Cholesterol, Dietary; Cortisone; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 7; Disease Models, Animal; Drug Therapy, Combination; Ezetimibe; Follow-Up Studies; Gas Chromatography-Mass Spectrometry; Gene Expression; Hypercholesterolemia; Hypophysectomy; Hypopituitarism; Injections, Subcutaneous; Intestinal Absorption; Lipoproteins; Liver; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Steroid Hydroxylases; Thyroxine; Treatment Outcome | 2008 |
Is Zetia a 'do nothing' drug?
Topics: Azetidines; Clinical Trials as Topic; Ezetimibe; Humans; Hypercholesterolemia; Hypolipidemic Agents; Molecular Structure | 2008 |
Ezetimibe for the treatment of primary (heterozygous-familial and non-familial) hypercholesterolaemia: NICE technology appraisal guidance.
Topics: Adult; Anticholesteremic Agents; Azetidines; Cardiovascular Diseases; Ezetimibe; Female; Heterozygote; Humans; Hypercholesterolemia; Lipids; Male; Practice Guidelines as Topic; Technology Assessment, Biomedical; Treatment Outcome | 2008 |
Commentary on NICE technology appraisal guidance on ezetimibe for the treatment of primary (heterozygous-familial and non-familial) hypercholesterolaemia.
Topics: Adult; Anticholesteremic Agents; Azetidines; Cardiovascular Diseases; Clinical Trials as Topic; Dose-Response Relationship, Drug; Ezetimibe; Female; Heterozygote; Humans; Hypercholesterolemia; Lipids; Male; Practice Guidelines as Topic; Technology Assessment, Biomedical; Treatment Outcome | 2008 |
Predictors of uncontrolled hyperlipidaemia in high-risk ambulatory patients in primary care.
Topics: Aged; Ambulatory Care; Anticholesteremic Agents; Azetidines; Cardiovascular Diseases; Cholesterol, LDL; Diabetes Mellitus; Ezetimibe; Female; Forecasting; Humans; Hypercholesterolemia; Male; Middle Aged; Primary Health Care; Prospective Studies; Risk Assessment; Simvastatin; Treatment Outcome | 2008 |
Ezetimibe combined with low-dose statin effectively lowers LDL in protease inhibitor treated patients.
Topics: Adult; Anticholesteremic Agents; Antiretroviral Therapy, Highly Active; Atorvastatin; Azetidines; Cholesterol, LDL; Drug Administration Schedule; Ezetimibe; Female; Follow-Up Studies; Heptanoic Acids; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Hypercholesterolemia; Lopinavir; Male; Middle Aged; Pilot Projects; Pravastatin; Prospective Studies; Pyrroles; Ritonavir; Treatment Outcome | 2008 |
Ezetimibe potently reduces vascular inflammation and arteriosclerosis in eNOS-deficient ApoE ko mice.
Topics: Animals; Anticholesteremic Agents; Apolipoproteins E; Arteriosclerosis; Azetidines; Blood Pressure; Endothelium, Vascular; Ezetimibe; Female; Hypercholesterolemia; Inflammation; Lipids; Male; Mice; Mice, Knockout; Nitric Oxide Synthase Type III | 2009 |
ENHANCE and ACCORD: controversy over surrogate end points.
Topics: Anticholesteremic Agents; Azetidines; Biomarkers; Clinical Trials as Topic; Clinical Trials, Phase IV as Topic; Endpoint Determination; Ezetimibe; Glycated Hemoglobin; Humans; Hypercholesterolemia; Research Design; Simvastatin | 2008 |
The cholesterol absorption inhibitor, ezetimibe, decreases diet-induced hypercholesterolemia in monkeys.
Topics: Animals; Anticholesteremic Agents; Azetidines; Cholesterol; Cholesterol Esters; Cholesterol, Dietary; Cholesterol, HDL; Cholesterol, LDL; Dose-Response Relationship, Drug; Ezetimibe; Female; Hypercholesterolemia; Macaca fascicularis; Macaca mulatta; Male; Time Factors; Triglycerides | 2001 |
Ezetimibe, a potent cholesterol absorption inhibitor, normalizes combined dyslipidemia in obese hyperinsulinemic hamsters.
Topics: Animals; Anticholesteremic Agents; Azetidines; Cholesterol; Cholesterol Esters; Cholesterol, HDL; Cholesterol, LDL; Cricetinae; Ezetimibe; Hypercholesterolemia; Hyperinsulinism; Hyperlipidemias; Hypertriglyceridemia; Liver; Mesocricetus; Obesity; Triglycerides | 2001 |
Ezetimibe (Schering-Plough).
Topics: Animals; Anticholesteremic Agents; Arteriosclerosis; Azetidines; Bile; Cholesterol; Cholesterol, LDL; Clinical Trials, Phase II as Topic; Down-Regulation; Drug Combinations; Drug Evaluation, Preclinical; Drug Therapy, Combination; Drugs, Investigational; Ezetimibe; Forecasting; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestinal Absorption; Intestinal Mucosa; Intestines; Molecular Structure; Simvastatin | 2001 |
The synergistic hypocholesterolemic activity of the potent cholesterol absorption inhibitor, ezetimibe, in combination with 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors in dogs.
Topics: Animals; Anticholesteremic Agents; Azetidines; Cholesterol; Cholesterol, Dietary; Dogs; Drug Combinations; Drug Synergism; Ezetimibe; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Liver; Lovastatin; Male; Pravastatin; Simvastatin; Time Factors | 2001 |
[Statins remain the standard. New methods for lipid lowering therapy].
Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Clinical Trials as Topic; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia | 2001 |