exudates and Nephrotic-Syndrome

Parental knowledge on nephrotic syndrome and disease relapse is important for early recognition and treatment of relapse to prevent the complications. Parental knowledge on nephrotic syndrome was reported to be inadequate from published studies. To date, there is no study on parental knowledge on childhood nephrotic syndrome in Malaysia. This study is thus aimed at to determine the level of knowledge on NS and disease relapse among parents of children with nephrotic syndrome and determine factors that influence knowledge on nephrotic syndrome and disease relapse.. This was a cross-sectional study conducted in Paediatric Nephrology Clinic, Hospital Selayang from November 2016 to November 2017. Seventy-eight parents were recruited based on universal sampling. Selfadministered questionnaire in Bahasa Malaysia and English was designed through focus group discussion with five subject matter experts and validated through content validity. Data was analysed using IBM SPSS Statistics 23.0.. Majority of parents or guardians (91%) were able to answer more than 50% of the questions correctly. Of these, 56% were able to answer more than 75% of the questions correctly. A 'cut-off' of 75% was defined as good knowledge. Parents of children with frequent relapses had higher parental knowledge and this was statistically significant (p=0.025).. Parental knowledge on nephrotic syndrome and disease relapse was still inadequate as only 56% parents had good knowledge. The main areas of deficit in parental knowledge were related to medications, infections, home urine dipstick monitoring, and recognition of warning signs during relapse.

Topics: Adolescent; Adult; Child; Child, Preschool; Cross-Sectional Studies; Female; Focus Groups; Health Knowledge, Attitudes, Practice; Humans; Malaysia; Male; Middle Aged; Nephrotic Syndrome; Parents; Prospective Studies; Recurrence

Renal biopsy is essential in the management of renal parenchymal diseases. Thus far there is no publish report on the pattern of glomerulonephritis in Kelantan. We decided to establish the pattern of glomerulonephritis in Kelantan and use this information as our reference in future studies. Records of patients who had proven glomerulonephritis histologically were analysed. Their biological data, clinical presentation, etiology and clinicopathological pattern were studied. Where appropriate mean and standard deviation were calculated. A total of 74 biopsies were performed during the study period (between January 1991 and December 1993), out of which 72 biopsies (97.3%) were considered suitable for analysis. The male to female ratio was 1:1.1. Mean age at presentation was 27.6 +/- 12.2 years. Nephrotic syndrome was the commonest clinical presentation (65.3%). The main underlying cause was systemic lupus erythematosus (50%) followed by primary glomerulonephritis. Histologically, IgA nephropathy and minimal change disease were the main patterns among patients with primary glomerulonephritis while diffuse proliferative glomerulonephritis was the commonest pattern among patients with lupus nephritis. Hence the pattern of glomerulonephritis is similar to other reported series. The procedure is considered safe and has a high success rate.

Topics: Adult; Biopsy; Female; Glomerulonephritis; Glomerulonephritis, IGA; Humans; Incidence; Lupus Nephritis; Malaysia; Male; Nephrotic Syndrome; Retrospective Studies; Sex Distribution

Topics: Adult; Biopsy; Female; Humans; Kidney; Lupus Nephritis; Malaysia; Male; Middle Aged; Nephrotic Syndrome

Topics: Adolescent; Adult; Child; Child, Preschool; Female; Humans; Kidney Glomerulus; Malaysia; Male; Middle Aged; Nephrotic Syndrome

Adequately biopsied renal tissue received in the Department of Pathology, University Hospital, Kuala Lumpur from 1,000 consecutive Malaysian patients during an eleven year period between 1970 and 1981 was reviewed. The youngest patient was 6 days old and the oldest 80 years. Both sexes were equally represented. The majority of the patients were Chinese (71%) with Malays and Indians comprising most of the remainder. Over half the patients (50.4%) presented with the nephrotic syndrome. Other modes of presentation included systemic lupus erythematosus, proteinuria and haematuria separately or in combination and hypertension. Minimal change (25.7%) and proliferative glomerulonephritis (24.8%) were present in about equal numbers and together accounted for over half of the cases (50.5%). Lupus nephritis was the third most common diagnosis (18.4%). In addition, there were patients with focal glomerulonephritis (5.4%), membranous glomerulonephritis (5.5%), Berger's disease (5.8%), amyloidosis (0.6%) and end stage renal disease (4.0%).

Topics: Adolescent; Adult; Aged; Asian People; Biopsy; Child; Child, Preschool; Female; Glomerulonephritis; Humans; Kidney; Kidney Diseases; Lupus Erythematosus, Systemic; Malaysia; Male; Middle Aged; Nephrosis, Lipoid; Nephrotic Syndrome

The first living patient with a Schistosoma japonicum-type infection who presented with the nephrotic syndrome is reported in detail. It is not clear whether the nephrotic syndrome was due to the schistosome infection or to the deposition of hepatitis B antigen and antibody complexes. This is the tenth case of schistosomiasis reported from aborigines in Malaysia and a sylvatic source of infection is suggested.

Topics: Adult; Hepatitis B; Humans; Liver; Malaysia; Male; Nephrotic Syndrome; Schistosoma japonicum; Schistosomiasis

Topics: Child; China; Cyclophosphamide; Female; Follow-Up Studies; Humans; India; Infant; Malaysia; Male; Nephrotic Syndrome; Sex Factors; Singapore; Steroids

Topics: Age Factors; Biopsy; Humans; Kidney Diseases; Malaysia; Nephrotic Syndrome; Racial Groups