exudates and Mitral-Valve-Stenosis

We describe two Malay male term neonates with congenital limb reduction defects. The first neonate had hypodactyly of limbs associated with micrognathia, microstomia, glossopalatine ankylosis and congenital mitral stenosis. He developed gram-negative septicaemia and died on day 14 of life. The second neonate had tetraperomelia without any other associated congenital abnormality. He developed staphylococcal skin infection which was treated conservatively. Very few cases of congenital limb reduction defects have been reported in the Asian population and we are not aware of any other reports describing Malay infants with the congenital abnormalities described in this report.

Topics: Abnormalities, Multiple; Humans; Infant, Newborn; Limb Deformities, Congenital; Malaysia; Male; Mitral Valve Stenosis; Syndrome; Tongue

Our experience from 1968 to 1985 in 12 women requiring closed mitral valvotomy during pregnancy is reviewed. All patients had severe mitral stenosis and were in functional class 3 (2 patients) or class 4 (10 patients). Mitral valvotomy was performed between the 18th and the 30th week of pregnancy using a transventricular dilator. Improvement in functional class was noted in all patients postoperatively. One patient had postvalvotomy mitral regurgitation and heart failure, which responded to diuretics; the subsequent course was uneventful. Eleven patients had normal deliveries; whilst one patient had a Caesarean section for an obstetric indication. All babies were normal and there was no maternal death. This series confirms that closed mitral valvotomy can be performed with an acceptable degree of safety during pregnancy, when indicated.

Topics: Abortion, Therapeutic; Adult; Female; Follow-Up Studies; Humans; Malaysia; Mitral Valve Stenosis; Postoperative Complications; Pregnancy; Pregnancy Complications, Cardiovascular; Reoperation; Rheumatic Heart Disease

Topics: Adolescent; Adult; Aged; Cardiac Surgical Procedures; Child; Child, Preschool; Coronary Disease; Heart Defects, Congenital; Heart Valve Diseases; Humans; Infant; Malaysia; Middle Aged; Mitral Valve Stenosis

Topics: Adult; Echocardiography; Female; Humans; Malaysia; Male; Middle Aged; Mitral Valve Stenosis; Rheumatic Heart Disease; Tricuspid Valve Stenosis

Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Female; Humans; Infant; Malaysia; Male; Mitral Valve Stenosis