exudates and Hypertrophy

Previously, we reported the presence of imported trichinellosis in a Thai worker returning from Malaysia, who presented with progressive generalized muscle hypertrophy and weakness after eating wild boar meat. This work analyzed a partial small subunit of a mitochondrial ribosomal RNA gene of Trichinella larvae isolated from the patient. The results showed complete identity with a mitochondrial RNA gene of Trichinella papuae (GenBank accession no. EF517130). This is the first report of imported trichinellosis in Thailand caused by T. papuae. It is possible that T. papuae is widely distributed in the wildlife of Southeast Asia.

Topics: Animals; Base Sequence; Humans; Hypertrophy; Larva; Malaysia; Meat; Mice; Molecular Sequence Data; Muscles; RNA; RNA, Helminth; RNA, Mitochondrial; RNA, Ribosomal; Sequence Alignment; Sequence Analysis, DNA; Sus scrofa; Thailand; Trichinella; Trichinellosis

Jering (Archidendron jiringa) is eaten in the tropics and traditionally extolled for treating diabetes, high blood pressure and eliminating bladder stones. Jering contains an unusual amino acid-djenkolic acid (S,S'-methylenebiscysteine)-which may form sharp crystals in the urinary tract, causing pain and haematuria. This study evaluates the beneficial and toxic effects of dietary jering on tissues and organs in normal and diabetic rats.. Dietary jering administered orally to diabetic rats significantly reduced the blood glucose in the streptozotocin-induced diabetic rats to normal levels after about 12 weeks. Jering improved the rats' appetite, body weight, organ oxidative status and number of active islets of Langerhans in both diabetic and normal rats, after 15 weeks of treatment. Although dietary jering showed beneficial effects to diabetic eye lens, lung and pancreas, it caused hypertrophy and lesions to the heart, kidney, liver, lung and pancreas of normal rats.. Chronic jering consumption showed toxic effects to the heart, kidney, liver and pancreas of normal rats but produced some beneficial effects to diabetic rats.

Topics: Animals; Body Weight; Cysteine; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Diet; Fabaceae; Hyperglycemia; Hypertrophy; Kidney; Liver; Malaysia; Male; Myocardium; Oxidative Stress; Pancreas; Random Allocation; Rats; Rats, Sprague-Dawley; Seeds

Topics: Female; Humans; Hypertrophy; Infant; Malaysia; Male; Peristalsis; Pyloric Stenosis; Racial Groups; Vomiting

Topics: China; Female; Humans; Hypertrophy; India; Infant, Newborn; Malaysia; Male; Pyloric Stenosis; Singapore