exudates and Gingivitis

This study aimed to compare the level of interleukin (IL)-10, IL-17, IL-27, IL-35, and IL-37 in the gingival crevicular fluid (GCF) and human plasma of subjects with periodontal disease.. In this cross-sectional study conducted over a 3-month period at a primary dental clinic in Malaysia, 45 participants were recruited via consecutive sampling and assigned into three groups, namely healthy periodontium group (. In GCF samples, IL-17 level was the highest in the periodontitis group (. There are reduced local and systemic levels of IL-27 in periodontitis patients.. Periodontal diseases exert both local and systemic effects, resulting in the destruction of the tooth-supporting structures and contributing to the systemic inflammatory burden. Some of the cytokines that were investigated in the current study, IL-17, IL-27, IL-35, and IL-37, can be potential biomarkers that warrant further longitudinal clinical studies to determine their usefulness as prognostic/diagnostic markers.

Topics: Cross-Sectional Studies; Gingival Crevicular Fluid; Gingivitis; Humans; Interleukin-10; Interleukin-17; Interleukin-27; Interleukins; Malaysia; Periodontal Diseases

Topics: Child; Child, Preschool; Dental Caries; Dental Health Surveys; Female; Gingivitis; Humans; Malaysia; Male; Oral Hygiene; Prevalence

Topics: Gingivitis; Humans; Malaysia; Temporomandibular Joint Dysfunction Syndrome; Tooth Diseases