exudates and Craniofacial-Abnormalities
exudates has been researched along with Craniofacial-Abnormalities* in 5 studies
Other Studies
5 other study(ies) available for exudates and Craniofacial-Abnormalities
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Diagnosis and treatment of branchial cleft anomalies in UKMMC: a 10-year retrospective study.
Branchial cleft anomalies result from abnormal persistence of branchial apparatus, which is located at the lateral part of the neck. These occur due to failure of obliteration of the branchial apparatus during embryonic development. Differential diagnoses of lateral neck mass are salivary gland or neurogenic neoplasms, paragangliomas, adenopathies, cystic hygroma or cystic metastasis from squamous cell carcinoma or thyroid papillary carcinoma. Clinically, a branchial cyst is smooth, round, fluctuant and non-tender, and usually occurs over the upper part of the neck, anterior to the sternocleidomastoid muscle. Sometimes, it may present as infected cyst (or abscess), a sinus or fistula. Surgical excision is the definitive treatment for branchial anomalies. The objective of the work was to study the demographic data, clinical presentation, definite diagnostic workup and treatment of patients diagnosed with branchial anomalies. This is a retrospective study of 26 patients who were diagnosed with branchial anomalies (branchial cyst and fistula), of which only 12 patients had data available between July 1999 and June 2009 at the Otorhinolaryngology, Head and Neck Surgery, Universiti Kebangsaan Malaysia Medical Centre. Twelve cases of branchial anomalies were seen, in which 10 patients had second branchial cyst anomalies, 1 had third branchial fistula and 1 had bilateral branchial lesion. There were seven females and five males. The age of the patients varied over a wide range (4-44 years), but the majority of the patients were in their second and third decade of life. All branchial anomalies occurred at the classical site; eight patients had left-sided neck lesion. Correct clinical diagnosis was made only in five patients (41.6 %). All patients underwent surgical excision with no reported recurrence. Branchial anomalies are frequently forgotten in the differential diagnosis of lateral neck swelling. Diagnosis is usually delayed, leading to improper treatment. The diagnosis of patients who present with lateral neck cystic swelling with or without episodes of recurrent neck abscess should be considered with a high suspicion for branchial anomalies. FNA cytology is a good investigative tool in reaching toward a diagnosis of branchial lesion, with the concurrent assistance of radiological modalities. Surgical excision is the gold standard treatment of lesions of branchial anomalies. Topics: Adolescent; Adult; Biopsy, Fine-Needle; Branchial Region; Child; Child, Preschool; Craniofacial Abnormalities; Diagnosis, Differential; Female; Humans; Malaysia; Male; Pharyngeal Diseases; Retrospective Studies; Young Adult | 2013 |
Craniofacial morphology of Malay patients with obstructive sleep apnoea.
The aim of this study was to compare the skeletal and soft tissue patterns between obstructive sleep apnoea (OSA) patients and control group of non-OSA patients. Fifty Malays (32 males and 18 females) aged 18-65 years divided into two equal groups 25 (17 males and 8 females) with OSA and a control group 25 subjects (15 males and 10 females). Both groups were diagnosed using polysomnography. Nineteen variables related to craniofacial skeletal and soft tissue morphology were measured on lateral cephalometric films. Analysis of covariance was used to compare the means between the two groups. The results showed that OSA subjects had a significant increase in body mass index (BMI) and neck circumference than the control group. The soft palate and tongue were longer and thicker in OSA patients. In addition, upper, middle, and lower posterior airway spaces were narrower, the hyoid bone was more inferior and posterior, and the cranial base flexure angle was significantly acute when compared with the control group. The findings indicate that craniofacial abnormalities play significant roles in the pathogenesis of OSA in Malay patients. Topics: Analysis of Variance; Body Mass Index; Case-Control Studies; Cephalometry; Craniofacial Abnormalities; Face; Facial Bones; Female; Humans; Malaysia; Male; Neck; Reference Values; Skull; Sleep Apnea, Obstructive | 2011 |
Craniofacial deformities in transfusion-dependent thalassemia patients in Malaysia: prevalence and effect of treatment.
This comparative cross-sectional study was conducted in the pediatric daycare unit, Hospital Universiti Sains Malaysia to determine the prevalence of craniofacial deformities (CFD) and the association between these deformities and different clinical presentations among thalassemia patients. Patients were classified as either craniofacial deformity positive (CFD+) or craniofacial deformity negative (CFD-) by two examiners based on the presence or absence of deformity of the cheeks, frontal and/or maxillary bones. Fifteen clinical parameters were compared between the groups. Nineteen out of 43 patients (44.2%; confidence interval, 30.2-58.2%) had craniofacial deformities (CFD+). Both groups were comparable among the clinical parameters studied. Patients in the CFD+ group did not start their blood transfusions significantly earlier than the CFD- group (p = 0.50) and had a nonsignificantly lower mean pretransfusion hemoglobin level than the CFD- group (p = 0.71). Patients receiving regular monthly blood transfusions had a nonsignificantly smaller percentage of CFD than those transfused less often (p = 0.495). CFD+ patients had a splenectomy at a nonsignificantly younger age than CFD- patients (p = 0.36). HbE/beta thalassemia patients were not significantly less likely to develop CFD than other varieties (p = 0.50) and males had a nonsignificantly higher percentage of CFD than females (p = 0.29). This study shows CFD in thalassemia patients are still prevalent but no significant associated factors were found; however, a nonsignificantly higher prevalence of CFD was observed in patients with signs of severe disease and less efficient treatment. Topics: Adolescent; Blood Transfusion; Child; Child, Preschool; Craniofacial Abnormalities; Cross-Sectional Studies; Erythropoiesis; Female; Humans; Malaysia; Male; Prevalence; Sex Factors; Thalassemia; Transfusion Reaction; Young Adult | 2011 |
Cytogenetic and clinical profile of Down syndrome in Northeast Malaysia.
This study was designed to evaluate the karyotype pattern, clinical features and other systemic anomalies of patients with Down syndrome in Malaysia.. Retrospective analysis was performed on the case records of 149 patients confirmed as Down syndrome by cytogenetic analysis at Human Genome Centre and Genetic Clinic at the Universiti Sains Malaysia.. Among the 149 cases of Down syndrome presenting over a period of 4.2 years, free trisomy (non-disjunction) was present in 141 cases (94.6 percent). One case (0.7 percent) had translocation, and seven cases (4.7 percent) were mosaics. Average age at presentation was 10.6 months. Average maternal age at birth of the affected child was 32.3 years. The prominent craniofacial features noted were upslanting palpebral fissures (89.3 percent), flat facial profile (64.9 percent), low set ears (56.1 percent), epicanthic folds (17.5 percent) and protruding tongue (19.2 percent). A total of 52.6 percent of the cases had documented hypotonia. Characteristic limb and dermatoglyphic anomalies included short stubby fingers (24.5 percent), sandal gap (33.3 percent), unilateral or bilateral simian crease (36.8 percent) and clinodactyly (19.2 percent). Ophthalmological abnormalities, such as hypertelorism, were presented in 33.3 percent of the cases. Congenital heart disease was diagnosed in 35 out of 71 cases (49.3 percent) and gastrointestinal anomalies were noted in 18 out of 79 cases (22.7 percent) analysed.. Efforts to establish early diagnosis and a proper screening for high association with systemic anomalies should be undertaken among the Down syndrome patients in this population. Topics: Adult; Cohort Studies; Congenital Hypothyroidism; Craniofacial Abnormalities; Down Syndrome; Female; Gastrointestinal Tract; Heart Defects, Congenital; Humans; Infant; Karyotyping; Limb Deformities, Congenital; Malaysia; Male; Maternal Age; Pregnancy; Retrospective Studies | 2007 |
Spectrum and management of dentofacial deformities in a multiethnic Asian population.
The aim of this retrospective study is to investigate the spectrum and management of dentofacial deformities in a multiethnic Asian community.. Over a period of 3 years (2001 to 2003), 212 patients with dentofacial deformities who had undergone orthognathic surgery in a national tertiary specialist center in Singapore were reviewed. Patients with cleft lip and palate or syndromes were excluded.. The mean age (range: 16 to 58 years) of the patients was 24.0 years (SD 6.4) and the ratio of female to male was 1.3:1. The predominant ethnic group was Chinese (91.5%). The majority of the patients had skeletal Class III pattern (68%). Asymmetry was diagnosed in 36% of all cases and in 48% of skeletal Class III cases. Vertical maxillary excess was diagnosed in 21% of all cases and in 47% of skeletal Class II cases. Bimaxillary surgery involving LeFort and bilateral sagittal split osteotomies was performed in 84% of skeletal Class III cases and in 73% of all cases. Segmental osteotomy and genioplasty were performed in 41% of the cases.. The findings suggest that the majority of the patients were young Chinese adults with two-jaw deformities requiring bimaxillary surgeries with genioplasty or segmental osteotomy. This finding may reflect the greater severity of dentofacial deformities in patients in the Asian community. Topics: Adolescent; Adult; Chin; China; Craniofacial Abnormalities; Ethnicity; Facial Asymmetry; Female; Humans; India; Malaysia; Male; Malocclusion; Malocclusion, Angle Class II; Malocclusion, Angle Class III; Maxilla; Middle Aged; Osteotomy; Osteotomy, Le Fort; Retrospective Studies; Singapore | 2006 |