exudates and Choriocarcinoma

Gestational trophoblastic disease is a common gynaecological problem in Malaysia. The incidence of molar pregnancy is 2.8 per 1000 deliveries, being more common amongst the Chinese. The preferred method of evacuation is suction curettage; complete evacuation of the uterus was not achieved at the first attempt in 25 per cent of cases. Partial moles in our centre comprised 30 per cent of all moles. This is potentially malignant and needs follow-up for a complete mole. In the management of an invasive mole, chemotherapy should not be withheld in the presence of metastases and failure of regression of hCG. The role of prophylactic hysterectomy and prophylactic chemotherapy in the management of molar pregnancy is discussed "Selective preventive chemotherapy" in patients at "risk" appears appropriate. Chemotherapy remains the main modality of treatment for gestational trophoblastic tumours (GTT). We categorised our patients into low, medium and high-risk groups; survivals were 100, 98, and 61.7 percent respectively. These patients when categorised according to FIGO staging had survivals of 100, 80, 78.6 and 68.2 per cent respectively for stages 1, 2, 3 and 4 respectively. The reasons for the poor survival in the 'high-risk' group are discussed. Colour doppler blood flow studies are now being carried out; its role needs further evaluation. Surgery and radiotherapy have only a limited role in the management of these cases.

Topics: Choriocarcinoma; Female; Humans; Hydatidiform Mole; Malaysia; Pregnancy; Trophoblastic Neoplasms; Uterine Neoplasms

Topics: Choriocarcinoma; Female; Humans; Malaysia; Pregnancy; Uterine Neoplasms

Topics: Adult; Choriocarcinoma; Female; Humans; Malaysia; Middle Aged; Pregnancy; Uterine Neoplasms

Topics: Adenoma, Pleomorphic; Adolescent; Adult; Age Factors; Aged; Carcinoma, Adenoid Cystic; Carcinoma, Squamous Cell; Child; Choriocarcinoma; Female; Humans; Malaysia; Male; Middle Aged; Mouth Neoplasms; Nasopharyngeal Neoplasms; Palatal Neoplasms; Pregnancy; Racial Groups; Tongue Neoplasms

Topics: ABO Blood-Group System; Blood Group Antigens; Choriocarcinoma; Female; Humans; Hydatidiform Mole; Malaysia; Pregnancy; Racial Groups; Remission, Spontaneous; Singapore; United States

Topics: Asian People; Cheek; Choriocarcinoma; Female; Humans; Malaysia; Male; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neoplasms; Pregnancy

Topics: Aging; Allergy and Immunology; Asian People; Blood Group Antigens; Blood Protein Electrophoresis; Choriocarcinoma; Female; Fertility; Geography; Humans; Hydatidiform Mole; Incidence; Liver Function Tests; Malaysia; Nutritional Physiological Phenomena; Nutritional Sciences; Pregnancy; Sociology; Statistics as Topic; Trophoblastic Neoplasms; Uterine Neoplasms