exudates and Cholangitis

To examine the medical status of children with biliary atresia (BA) surviving with native livers.. In this cross-sectional review, data collected included complications of chronic liver disease (CLD) (cholangitis in the preceding 12 mo, portal hypertension, variceal bleeding, fractures, hepatopulmonary syndrome, portopulmonary hypertension) and laboratory indices (white cell and platelet counts, total bilirubin, albumin, international normalized ratio, alanine aminotransferase, aspartate aminotransferase, γ-glutamyl transpeptidase). Ideal medical outcome was defined as absence of clinical evidence of CLD or abnormal laboratory indices.. Fifty-two children [females = 32, 62%; median age 7.4 years,. Clinical or laboratory evidence of CLD are present in 98% of children with BA living with native livers after hepatoportoenterostomy. Portal hypertension and variceal bleeding may be seen in children younger than 5 years of age, underscoring the importance of medical surveillance for complications of BA starting at a young age.

Topics: Adolescent; Biliary Atresia; Child; Child, Preschool; Cholangitis; Chronic Disease; Cross-Sectional Studies; Esophageal and Gastric Varices; Female; Follow-Up Studies; Fractures, Bone; Gastrointestinal Hemorrhage; Hepatopulmonary Syndrome; Humans; Hypertension, Portal; Liver; Liver Function Tests; Malaysia; Male; Portoenterostomy, Hepatic

Topics: Adult; Aged; Aged, 80 and over; Animals; Ascariasis; Ascaris lumbricoides; Cholangitis; Cholelithiasis; Female; Gallstones; Humans; Malaysia; Male; Middle Aged; Rural Health

Topics: Age Factors; Biliary Tract Diseases; China; Cholangitis; Cholecystitis; Cholelithiasis; Ethnicity; India; Malaysia; Obesity; Sex Factors