exudates and Bronchiolitis

Topics: Adult; Aftercare; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Inflammatory Agents; Azithromycin; Bronchiolitis; CD4 Lymphocyte Count; Denmark; Dyspnea; Granulomatosis with Polyangiitis; HIV Infections; Humans; Malaysia; Male; Pneumonia, Pneumocystis; Prednisolone; Rare Diseases; Respiratory Function Tests; Sustained Virologic Response; Thailand; Tomography, X-Ray Computed; Treatment Outcome; Viral Load

Topics: Bronchiolitis; Humans; Infant; Malaysia; Pneumonia, Viral; Respiratory Syncytial Virus Infections

Topics: Bronchiolitis; Child, Preschool; Cost of Illness; Female; Hospitals, Teaching; Humans; Malaysia; Male; Medical Audit; Respiratory Syncytial Virus Infections

Twenty-two (42 per cent) out of 52 patients admitted with severe bronchiolitis to our Paediatric Intensive Care Unit required ventilation. Risk factors associated with ventilation included a younger mean age, female sex, low birthweight, failure to thrive and the presence of an underlying illness. Ventilated patients were also more likely to have a higher respiratory distress assessment index (RDAI) score, pneumonic infiltration on chest X-ray, lower serum sodium and a positive respiratory syncytial virus isolation in the tracheal secretion.

Topics: Bronchiolitis; Female; Humans; Infant; Infant, Newborn; Malaysia; Male; Respiration, Artificial; Risk Factors; Severity of Illness Index; X-Rays

To study the viral aetiology of lower respiratory tract infection (LRTI) in young Malaysian children.. A retrospective review was performed of LRTI patients aged less than 24 months who were admitted to the University Malaya Medical Centre between 1982 and 1997. Respiratory viruses in their nasopharyngeal secretion were identified by indirect immunofluorescence, viral culture, or both.. A total of 5691 children were included in the study. The mean age was 8.6 +/- 6.6 months and the M:F ratio was 1.6:1. The most common diagnosis was pneumonia (52%) followed by bronchiolitis (45%) and croup (2%). Positive viral isolation rate was 22.0%. Respiratory syncytial virus (RSV) was the commonest virus isolated (84%), followed by parainfluenza virus (8%), influenza virus (6%) and adenovirus (2%). Patients with positive virus isolation were younger (7.8 +/- 6.2 vs 8.7 +/- 6.7 months, P = 0.0001) and were more likely to have bronchiolitis.. Young Malaysian children admitted with LRTI had a 22% viral isolation rate and RSV was the commonest virus isolated.

Topics: Bronchiolitis; Croup; Female; Humans; Infant; Infant, Newborn; Malaysia; Male; Pneumonia, Viral; Retrospective Studies