exudates and Bronchial-Neoplasms

Multiple lung cavitations and endobronchial nodules are rare presentations of newly diagnosed and recurrent Hodgkin's disease. The clinical and radiological features can be confused with pulmonary tuberculosis, which can be difficult to exclude in endemic areas. However, the presence of endobronchial nodules point, towards Hodgkin's disease. Differential diagnosis is aided by the fact that these lesions usually respond promptly to specific therapy. We present a case of an adolescent male who had constitutional and pulmonary symptoms associated with pulmonary cavities and endobronchial nodules subsequently confirmed to be Hodgkin's disease.

Topics: Adolescent; Bronchial Neoplasms; Diagnosis, Differential; Hodgkin Disease; Humans; Lung; Malaysia; Male; Neoplasm Recurrence, Local; Radiography

Two hundred and ninety-three bronchoscopies were done for 285 patients (78% males, 22% females) at Hospital University Sains Malaysia between 1984 and 1988. The mean age was 56.4 years (range 13 to 90 years). 70.2% of patients underwent bronchoscopies to confirm or exclude the diagnosis of carcinoma of the bronchus, out of which 58% were confirmed to have bronchial carcinoma. 77% of the 98 patients with visible endobronchial tumours had biopsy specimens diagnostic of malignancy. Brushing and washing cytology increased the positive yield to 92%. The commonest histological type of bronchial carcinoma identified was squamous cell carcinoma (48.1%), followed by small cell carcinoma (27.1%), anaplastic/undifferentiated carcinoma (12.9%), adenocarcinoma (9.4%) and large cell carcinoma (2.4%). Bronchoscopy for the investigation of haemoptysis identified the commonest cause as 'bronchitis'. There were no complications noted in our series. Notable differences of our experience compared to that of the western series were the high percentage of bronchoscopy done for infective respiratory disorders and the younger age of our patients.

Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biopsy; Bronchial Neoplasms; Bronchoscopy; Carcinoma; Carcinoma, Bronchogenic; Female; Fiber Optic Technology; Hemoptysis; Humans; Lung Diseases; Lung Neoplasms; Malaysia; Male; Middle Aged

Topics: Adenocarcinoma; Asian People; Bronchial Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Humans; Malaysia