exendin-(9-39) and Diabetic-Retinopathy

In the early stage of diabetic retinopathy, the damage of retinal ganglion cells already exists, promoting the development of the disease. The aim of this study was to investigate the protective role and the mechanisms of obestatin against H. RGC-5 cells were incubated with various concentrations of obestatin for 24h before H. Obestatin prevents H

Topics: Animals; bcl-2-Associated X Protein; Blotting, Western; Cell Line; Cell Survival; Diabetic Retinopathy; Ghrelin; Glucagon-Like Peptide-1 Receptor; Hydrogen Peroxide; Peptide Fragments; Proto-Oncogene Proteins c-bcl-2; Receptor, trkB; Retinal Ganglion Cells