exenatide and Esophageal-Neoplasms

A 61-year-old woman with biochemically proven endogenous hyperinsulinemic hypoglycemia and negative conventional imaging underwent 68Ga-NOTA-exendin-4 PET/CT for localization of insulinoma. Focal intense radioactivity in the tail of the pancreas was observed that was subsequently confirmed as insulinoma pathologically after surgical resection. In addition, esophageal carcinoma with lymph node and hepatic metastases was found by FDG PET/CT in the same patient. Neither the primary carcinoma nor the metastases showed increased radioactivity on 68Ga-NOTA-exendin-4 PET/CT.

Topics: Carcinoma; Coordination Complexes; Esophageal Neoplasms; Exenatide; Female; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Humans; Insulinoma; Liver Neoplasms; Middle Aged; Multimodal Imaging; Pancreatic Neoplasms; Peptides; Positron-Emission Tomography; Radiopharmaceuticals; Tomography, X-Ray Computed; Venoms