evernimicin has been researched along with Lyme-Disease* in 1 studies
1 other study(ies) available for evernimicin and Lyme-Disease
Article | Year |
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Efficacy of an evernimicin (SCH27899) in vitro and in an animal model of Lyme disease.
The MICs of evernimicin at which 90% of Borrelia burgdorferi patient isolates were inhibited ranged from 0.1 to 0.5 microg/ml. Evernimicin was as effective as ceftriaxone against B. burgdorferi in a murine model of experimental Lyme disease. As assessed by culturing the urinary bladders of infected C3H mice, no live Borrelia isolates were recoverable following antibiotic treatment. Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Borrelia burgdorferi Group; Ceftriaxone; Cephalosporins; Disease Models, Animal; Female; Lyme Disease; Mice; Mice, Inbred C3H; Microbial Sensitivity Tests; Treatment Outcome | 2001 |