evans blue has been researched along with Cerebral Infarction, Middle Cerebral Artery in 48 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.08) | 18.2507 |
| 2000's | 21 (43.75) | 29.6817 |
| 2010's | 19 (39.58) | 24.3611 |
| 2020's | 7 (14.58) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, G; Huang, L; Liang, J; Song, K; Xie, X; Zeng, X; Zhu, R | 1 |
| Fang, T; Han, B; Li, N; Liu, W; Meng, Z; Wang, Y; Yao, J; Zhao, Y | 1 |
| Ding, H; Jiang, X; Li, C; Li, X; Li, Z; Zeng, H; Zhang, S; Zhang, Y | 1 |
| Ashiqueali, R; Clendaniel, V; Fisher, M; Lin, CI; Lo, EH; Lu, H; Matheson, R; Selim, M; Shehadah, A; Walchale, A | 1 |
| Chen, X; He, X; Hou, W; Huang, H; Lin, X; Liu, J; Wei, J; Yang, GY; Yao, J; Yin, X | 1 |
| Fan, WP; Yan, HS; Zhuang, Y | 1 |
| Cui, W; Feng, Y; Liu, F; Sang, J; Wu, Z; Xiao, X; Yan, S; Yang, M; Ye, S | 1 |
| Fan, B; Feng, J; Han, D; Sun, M; Wen, LL; Zhang, H; Zhang, S | 1 |
| Arrick, DM; Baluna, AE; Jiang, Z; Li, C; Sun, H; Yang, S | 1 |
| Alkayed, NJ; Ao, G; Cheng, J; Du, H; Hu, L; Jia, J; Liu, CF; Liu, H; Wang, Y; Xiao, Y | 1 |
| Li, L; Li, Y; Liu, WY; Luan, P; Tong, LC; Wang, Y; Wang, ZB; Wei, X | 1 |
| Gidday, JM; Kong, X; Ortega, SB; Plautz, EJ; Poinsatte, K; Selvaraj, UM; Stowe, AM | 1 |
| Jin, X; Liu, W; Liu, Y; Sun, Y; Wang, X | 1 |
| Furuichi, Y; Maeda, M; Matsuoka, N; Mutoh, S; Noto, T; Yoneda, Y | 1 |
| Hendren, J; Liu, KJ; Liu, W; Qin, XJ; Shen, J | 1 |
| Dong, H; Fan, YH; Wang, Q; Xiong, LZ; Yang, QZ; Zhang, W | 1 |
| Butman, JA; Johnson, DL; Oldfield, EH; Pluta, RM; Schatlo, B | 1 |
| Hara, H; Iwama, T; Nonaka, Y; Shimazawa, M; Tsuruma, K; Yoshimura, S | 1 |
| Bachmann, G; Gerriets, T; Kaps, M; Mueller, C; Nedelmann, M; Ritschel, N; Schoenburg, M; Tschernatsch, M; Walberer, M | 1 |
| Bourayou, R; Cordell, R; Dirnagl, U; Klohs, J; Licha, K; Lindauer, U; Mueller, S; Schirner, M; Steinbrink, J; Wunder, A | 1 |
| Bai, C; Fu, R; Tang, C; Wu, A; Xue, H | 1 |
| Jung, YS; Lee, DH; Park, SL; Yoo, SE | 1 |
| Chen, C; Duan, W; Han, J; Hu, Q; Khatibi, NH; Li, L; Wang, K; Yang, L; Zhang, JH; Zhou, C | 1 |
| Chuang, DM; Leeds, P; Leng, Y; Tsai, LK; Wang, Z | 1 |
| Battaglia, G; Bruno, V; Fardone, E; Kortenska, LV; Mastroiacovo, F; Mitreva, RG; Moyanova, SG; Ngomba, RT; Nicoletti, F; Santolini, I; Sobrado, M | 1 |
| Jiao, H; Liu, Y; Wang, P; Wang, Z; Xue, Y | 1 |
| Ding, S; Li, Z; Liu, K; Wu, T | 1 |
| Jiang, X; Xi, G; Xing, Y; Yang, Y | 1 |
| Chen, X; Chung, SK; Gu, Y; Li, Y; Liu, KJ; Shen, J; Tong, Y; Xu, M; Zheng, G; Zhu, W | 1 |
| Daneman, R; Derugin, N; Faustino, J; Fernández-López, D; Lee, SY; Vexler, ZS; Wendland, MF; Zhou, L | 1 |
| Chen, J; Chopp, M; Cui, X; Lu, M; Ning, R; Roberts, C; Yan, T; Zacharek, A; Zhang, C | 1 |
| Dhammu, TS; Gilg, AG; Khan, M; Sakakima, H; Shunmugavel, A; Singh, AK; Singh, I | 1 |
| Chen, B; Lei, IF; Lyden, PD; Pereira, B; Rajput, PS; Van Winkle, JA | 1 |
| Bugge, TH; Lawrence, DA; Moore, EG; Sandkvist, M; Strickland, DK; Yepes, M | 1 |
| Chen, AY; Chung, SK; Chung, SS; Fung, MK; Ho, MC; Hung, VK; Lo, AC; Tsang, MC; Yaw, LP | 1 |
| Chen, LP; Chu, SL; Wei, EQ; Xu, HM; Yu, GL; Zhang, Q; Zhang, SH; Zhao, W; Zhu, ZY | 1 |
| Calvert, JW; Matchett, G; Ohkuma, H; Shimamura, N; Yatsushige, H; Zhang, J | 1 |
| Cahill, J; Solaroglu, I; Tsubokawa, T; Yata, K; Yatsushige, H; Zhang, JH | 1 |
| Estrada, EY; Liu, W; Rosenberg, GA; Thompson, JF; Yang, Y | 1 |
| Chang, GL; Chen, HY; Chen, ST; Chen, TY; Hsu, YS; Kuo, YL; Lee, EJ; Lee, MY; Wu, TS | 1 |
| Albert, M; Benedek, A; Gigler, G; Hársing, LG; Jurányi, Z; Lévay, G; Mátyus, P; Móricz, K; Szénási, G | 1 |
| Matchett, G; Ohkuma, H; Shimamura, N; Solaroglu, I; Tsubokawa, T; Zhang, J | 1 |
| Brown, SL; Fenstermacher, JD; Keenan, KA; Knight, RA; Nagaraja, TN | 1 |
| Li, Y; Lu, ZY; Ogle, M; Wei, L | 1 |
| Hosseinzadeh, F; Sadogh, T; Vakili, A | 1 |
| Fenstermacher, JD; Keenan, KA; Knight, RA; Nagaraja, TN | 1 |
| Chan, PH; Fujimura, M; Gasche, Y; Kawase, M; Massengale, J; Morita-Fujimura, Y | 1 |
| Bolay, H; Dalkara, T; Gürsoy-Ozdemir, Y; Saribaş, O | 1 |
48 other study(ies) available for evans blue and Cerebral Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Dl-3-n-butylphthalide attenuates brain injury caused by cortical infarction accompanied by cranial venous drainage disturbance.
Topics: Animals; Benzofurans; Brain Injuries; Brain Ischemia; Drainage; Endothelial Cells; Evans Blue; Infarction, Middle Cerebral Artery; Ischemic Stroke; Rats; Rats, Sprague-Dawley; Stroke | 2022 |
Proteomics on the role of muscone in the "consciousness-restoring resuscitation" effect of musk on ischemic stroke.
Topics: Animals; Brain Ischemia; Cerebral Infarction; Consciousness; Cycloparaffins; Disease Models, Animal; Evans Blue; Fatty Acids, Monounsaturated; Infarction, Middle Cerebral Artery; Ischemic Stroke; Necrosis; Proteomics; Rats; Stroke | 2022 |
Human albumin aggravates cerebral edema by disrupting the blood‑brain barrier in a rat model of ischemic stroke.
Topics: Animals; Blood-Brain Barrier; Brain Edema; Brain Ischemia; Claudin-5; Endothelial Cells; Evans Blue; Humans; Infarction, Middle Cerebral Artery; Ischemic Stroke; Matrix Metalloproteinase 9; Occludin; Rats; Rats, Sprague-Dawley; Serum Albumin, Human; Stroke; Tight Junction Proteins | 2022 |
Histone Deacetylase 3 Inhibition Decreases Cerebral Edema and Protects the Blood-Brain Barrier After Stroke.
Topics: Albumins; Animals; Aquaporins; Blood-Brain Barrier; Brain Edema; Claudin-5; Evans Blue; Infarction, Middle Cerebral Artery; Male; Matrix Metalloproteinase 9; NF-kappa B; Rats; Rats, Wistar; Stroke | 2023 |
USP14 inhibition promotes recovery by protecting BBB integrity and attenuating neuroinflammation in MCAO mice.
Topics: Animals; Blood-Brain Barrier; Brain Injuries; Brain Ischemia; Endothelial Cells; Evans Blue; Immunoglobulin G; Infarction, Middle Cerebral Artery; Ischemic Stroke; Mice; Neuroinflammatory Diseases; Stroke | 2023 |
Overexpression of Circ_0005585 Alleviates Cerebral Ischemia Reperfusion Injury via Targeting MiR-16-5p.
Topics: Animals; Apoptosis; Brain Ischemia; Evans Blue; Infarction, Middle Cerebral Artery; Ischemic Stroke; Mice; MicroRNAs; Reperfusion Injury | 2023 |
Evans Blue Might Produce Pathologically Activated Neuroprotective Effects via the Inhibition of the P2X4R/p38 Signaling Pathway.
Topics: Animals; Behavior, Animal; Brain Infarction; Cell Death; Cell Line; Evans Blue; Infarction, Middle Cerebral Artery; Iodoacetic Acid; Male; Mice; Models, Biological; Molecular Docking Simulation; Neurons; Neuroprotective Agents; p38 Mitogen-Activated Protein Kinases; Rats, Sprague-Dawley; Receptors, Purinergic P2X4; RNA, Messenger; Signal Transduction | 2021 |
Ischemic postconditioning protects the neurovascular unit after focal cerebral ischemia/reperfusion injury.
Topics: Animals; Blood-Brain Barrier; Capillary Permeability; Cerebral Cortex; Evans Blue; Infarction, Middle Cerebral Artery; Ischemic Postconditioning; Rats; Reperfusion Injury; Tight Junction Proteins | 2014 |
Role of nitric oxide synthases in early blood-brain barrier disruption following transient focal cerebral ischemia.
Topics: Animals; Blood-Brain Barrier; Cerebrovascular Circulation; Cerebrum; Evans Blue; Fluorescein; Fluorescent Dyes; Infarction, Middle Cerebral Artery; Male; Mice, Inbred C57BL; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Regional Blood Flow; Reperfusion Injury; Vasodilation | 2014 |
Hydrogen sulfide protects blood-brain barrier integrity following cerebral ischemia.
Topics: Animals; Behavior, Animal; Blood-Brain Barrier; Blotting, Western; Brain Edema; Brain Ischemia; Coloring Agents; Enzyme-Linked Immunosorbent Assay; Evans Blue; Heterocyclic Compounds, 1-Ring; Hydrogen Sulfide; Infarction, Middle Cerebral Artery; Interleukin-10; Male; Mice; Mice, Inbred ICR; NADPH Oxidases; Neuroprotective Agents; NF-kappa B; Peroxidase; Real-Time Polymerase Chain Reaction; Thiones | 2014 |
Increasing the Permeability of the Blood-brain Barrier in Three Different Models in vivo.
Topics: Animals; Antigens, CD; Blood-Brain Barrier; Cadherins; Caveolin 1; Claudin-5; Disease Models, Animal; Encephalitis; Evans Blue; Infarction, Middle Cerebral Artery; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Permeability; Spinal Cord Injuries | 2015 |
Quantification of neurovascular protection following repetitive hypoxic preconditioning and transient middle cerebral artery occlusion in mice.
Topics: Animals; Blood-Brain Barrier; Brain; Disease Models, Animal; Evans Blue; Hypoxia; Infarction, Middle Cerebral Artery; Ischemic Preconditioning; Laser-Doppler Flowmetry; Male; Mice; Random Allocation | 2015 |
Blood brain barrier breakdown was found in non-infarcted area after 2-h MCAO.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Ischemia; Evans Blue; Infarction, Middle Cerebral Artery; Rats; Rats, Sprague-Dawley; Time Factors | 2016 |
Tacrolimus (FK506) suppresses rt-PA-induced hemorrhagic transformation in a rat thrombotic ischemia stroke model.
Topics: Animals; Blood-Brain Barrier; Brain; Endothelial Cells; Evans Blue; Immunohistochemistry; Immunosuppressive Agents; Infarction, Middle Cerebral Artery; Male; Microvessels; Platelet Endothelial Cell Adhesion Molecule-1; Rats; Rats, Inbred SHR; Recombinant Proteins; Tacrolimus; Tissue Plasminogen Activator | 2009 |
Normobaric hyperoxia attenuates early blood-brain barrier disruption by inhibiting MMP-9-mediated occludin degradation in focal cerebral ischemia.
Topics: Animals; Blood-Brain Barrier; Blotting, Western; Capillaries; Coloring Agents; Evans Blue; Gelatin; Immunohistochemistry; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Membrane Proteins; Occludin; Oxygen Inhalation Therapy; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tight Junctions | 2009 |
Repeated electroacupuncture preconditioning attenuates matrix metalloproteinase-9 expression and activity after focal cerebral ischemia in rats.
Topics: Animals; Blood-Brain Barrier; Blotting, Western; Body Water; Brain; Brain Edema; Brain Ischemia; Capillary Permeability; Electroacupuncture; Electrophoresis, Polyacrylamide Gel; Evans Blue; Infarction, Middle Cerebral Artery; Male; Matrix Metalloproteinase 9; Random Allocation; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Time Factors | 2009 |
Subarachnoid hemorrhage and the distribution of drugs delivered into the cerebrospinal fluid. Laboratory investigation.
Topics: Animals; Cisterna Magna; Coloring Agents; Contrast Media; Evans Blue; Image Processing, Computer-Assisted; Infarction, Middle Cerebral Artery; Injections, Spinal; Iopamidol; Macaca fascicularis; Pharmaceutical Preparations; Subarachnoid Hemorrhage; Thrombolytic Therapy; Tomography, X-Ray Computed; Vasospasm, Intracranial | 2009 |
Cilostazol protects against hemorrhagic transformation in mice transient focal cerebral ischemia-induced brain damage.
Topics: Animals; Brain; Brain Ischemia; Cerebral Hemorrhage; Cerebral Infarction; Cilostazol; Disease Models, Animal; Evans Blue; Indicators and Reagents; Infarction, Middle Cerebral Artery; Male; Mice; Neuroprotective Agents; Tetrazoles; Treatment Outcome | 2009 |
Edema formation in the hyperacute phase of ischemic stroke. Laboratory investigation.
Topics: Animals; Body Temperature; Brain Edema; Brain Ischemia; Evans Blue; Hemodynamics; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Male; Rats; Rats, Sprague-Dawley; Stroke; Time Factors | 2009 |
Near-infrared fluorescence imaging with fluorescently labeled albumin: a novel method for non-invasive optical imaging of blood-brain barrier impairment after focal cerebral ischemia in mice.
Topics: Albumins; Animals; Blood-Brain Barrier; Brain Edema; Brain Ischemia; Evans Blue; Fluorescent Dyes; Gadolinium DTPA; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Serum Albumin, Bovine; Spectroscopy, Near-Infrared | 2009 |
The effects of Tanshinone IIA on blood-brain barrier and brain edema after transient middle cerebral artery occlusion in rats.
Topics: Abietanes; Animals; Blood-Brain Barrier; Brain; Edema; Evans Blue; Infarction, Middle Cerebral Artery; Intercellular Adhesion Molecule-1; Ischemic Attack, Transient; Matrix Metalloproteinase 9; Membrane Proteins; Occludin; Permeability; Phenanthrenes; Phytotherapy; Plant Extracts; Plant Roots; Rats; Reperfusion Injury; Salvia miltiorrhiza; Tight Junctions; Water | 2010 |
The effect of Na(+)/H(+) exchanger-1 inhibition by sabiporide on blood-brain barrier dysfunction after ischemia/hypoxia in vivo and in vitro.
Topics: Analysis of Variance; Animals; Blood-Brain Barrier; Brain; Calcium; Carbon Isotopes; Cells, Cultured; Cytoskeletal Proteins; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Evans Blue; Gene Expression; Guanidines; Infarction, Middle Cerebral Artery; Male; Membrane Proteins; Mice; Neuroglia; Occludin; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium-Hydrogen Exchangers; Sucrose; Tight Junctions | 2010 |
Lentivirus-mediated transfer of MMP-9 shRNA provides neuroprotection following focal ischemic brain injury in rats.
Topics: Analysis of Variance; Animals; Blood-Brain Barrier; Cell Line, Transformed; Cells, Cultured; Disease Models, Animal; Evans Blue; Gene Expression Regulation; Gene Transfer Techniques; Infarction, Middle Cerebral Artery; Lentivirus; Male; Matrix Metalloproteinase 9; Rats; Rats, Sprague-Dawley; RNA, Messenger; RNA, Small Interfering; Single-Blind Method; Tetrazolium Salts; Trauma Severity Indices | 2011 |
Valproic acid attenuates blood-brain barrier disruption in a rat model of transient focal cerebral ischemia: the roles of HDAC and MMP-9 inhibition.
Topics: Animals; Blood-Brain Barrier; Blotting, Western; Body Water; Brain Chemistry; Brain Edema; Butyrates; Coloring Agents; Evans Blue; Histone Deacetylase Inhibitors; Histone Deacetylases; Immunoglobulin G; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Male; Matrix Metalloproteinase Inhibitors; Neuroprotective Agents; NF-kappa B; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Tight Junctions; Valproic Acid | 2011 |
Protective role for type 4 metabotropic glutamate receptors against ischemic brain damage.
Topics: Animals; Behavior, Animal; Brain; Cerebral Infarction; Coloring Agents; Electroencephalography; Evans Blue; Female; Forelimb; Hindlimb; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Postural Balance; Psychomotor Performance; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Reflex | 2011 |
Specific role of tight junction proteins claudin-5, occludin, and ZO-1 of the blood-brain barrier in a focal cerebral ischemic insult.
Topics: Animals; Blood-Brain Barrier; Brain Ischemia; Claudin-5; Coloring Agents; Evans Blue; Infarction, Middle Cerebral Artery; Male; Membrane Proteins; Occludin; Permeability; Phosphoproteins; Protein Kinase C-delta; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tight Junctions; Zonula Occludens-1 Protein | 2011 |
Role of rho kinase in microvascular damage following cerebral ischemia reperfusion in rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blood-Brain Barrier; Capillary Permeability; Evans Blue; Infarction, Middle Cerebral Artery; Laminin; Male; Matrix Metalloproteinase 9; Microvessels; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; RNA, Messenger | 2011 |
Hemorrhagic transformation induced by acute hyperglycemia in a rat model of transient focal ischemia.
Topics: Animals; Blood-Brain Barrier; Brain Edema; Disease Models, Animal; Evans Blue; Functional Laterality; Glucose; Hemoglobins; Hemorrhage; Hyperglycemia; Infarction, Middle Cerebral Artery; Male; Rats; Rats, Sprague-Dawley; Reperfusion; Time Factors | 2011 |
Caveolin-1 regulates nitric oxide-mediated matrix metalloproteinases activity and blood-brain barrier permeability in focal cerebral ischemia and reperfusion injury.
Topics: Animals; Blood-Brain Barrier; Blotting, Western; Brain Chemistry; Brain Ischemia; Capillaries; Caveolin 1; Coloring Agents; Enzyme Inhibitors; Evans Blue; Infarction, Middle Cerebral Artery; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Permeability; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2012 |
Blood-brain barrier permeability is increased after acute adult stroke but not neonatal stroke in the rat.
Topics: Age Factors; Animals; Animals, Newborn; Blood-Brain Barrier; Brain; Capillary Permeability; Collagen; Dextrans; Disease Models, Animal; Endothelial Cells; Evans Blue; Female; Fluorescent Dyes; Functional Laterality; Gadolinium DTPA; Gene Expression Regulation; Image Processing, Computer-Assisted; Infarction, Middle Cerebral Artery; Lectins; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Male; Membrane Proteins; Radiography; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Reperfusion; Serum Albumin, Bovine; Statistics, Nonparametric; Time Factors | 2012 |
Tissue plasminogen activator treatment of stroke in type-1 diabetes rats.
Topics: Animals; Blood-Brain Barrier; Blotting, Western; Cerebral Hemorrhage; Coloring Agents; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Evans Blue; Fibrinolytic Agents; Immunohistochemistry; Infarction, Middle Cerebral Artery; Male; Matrix Metalloproteinase 9; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Recovery of Function; Stroke; Tissue Plasminogen Activator; Toll-Like Receptor 4; Treatment Outcome | 2012 |
The inhibitory effect of S-nitrosoglutathione on blood-brain barrier disruption and peroxynitrite formation in a rat model of experimental stroke.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Edema; Carrier Proteins; Disease Models, Animal; E-Selectin; Endothelial Cells; Evans Blue; Functional Laterality; Infarction, Middle Cerebral Artery; Male; Matrix Metalloproteinase 9; Neoplasm Proteins; Neurons; Neuroprotective Agents; NF-kappaB-Inducing Kinase; Nitric Oxide; Nitrites; Nucleocytoplasmic Transport Proteins; Peroxynitrous Acid; Phosphopyruvate Hydratase; Protein Serine-Threonine Kinases; Protein Transport; Rats; Rats, Sprague-Dawley; S-Nitrosoglutathione; Statistics, Nonparametric; Time Factors; Tyrosine; Zonula Occludens-1 Protein | 2012 |
Concurrent middle cerebral artery occlusion and intra-arterial drug infusion via ipsilateral common carotid artery catheter in the rat.
Topics: Anesthesia; Animals; Brain Ischemia; Carotid Artery, Common; Catheterization, Peripheral; Coloring Agents; Evans Blue; Functional Laterality; Infarction, Middle Cerebral Artery; Infusions, Intravenous; Injections, Intra-Arterial; Jugular Veins; Male; Neurologic Examination; Rats; Rats, Sprague-Dawley; Reperfusion; Stroke; Sutures | 2013 |
Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein.
Topics: Animals; Antibodies; Blood-Brain Barrier; Brain; Brain Ischemia; Capillary Permeability; Coloring Agents; Dose-Response Relationship, Drug; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Homeostasis; Humans; Infarction, Middle Cerebral Artery; Low Density Lipoprotein Receptor-Related Protein-1; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuropeptides; Neuroserpin; Plasminogen; Rats; Rats, Sprague-Dawley; Serine Proteinase Inhibitors; Serpins; Tissue Plasminogen Activator | 2003 |
Endothelin-1 overexpression leads to further water accumulation and brain edema after middle cerebral artery occlusion via aquaporin 4 expression in astrocytic end-feet.
Topics: Animals; Aquaporin 4; Aquaporins; Astrocytes; Blood Pressure; Blood-Brain Barrier; Blotting, Western; Brain; Brain Edema; Coloring Agents; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Evans Blue; Glial Fibrillary Acidic Protein; In Situ Hybridization; Infarction, Middle Cerebral Artery; Mice; Mice, Transgenic; Nervous System Diseases; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; Water | 2005 |
[Photomacrography of brain surface for evaluating blood-brain barrier disruption within 24 h after focal cerebral ischemia in mice].
Topics: Animals; Blood-Brain Barrier; Brain; Evans Blue; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred ICR; Photography; Time Factors | 2005 |
Inhibition of integrin alphavbeta3 ameliorates focal cerebral ischemic damage in the rat middle cerebral artery occlusion model.
Topics: Animals; Blood-Brain Barrier; Brain Edema; Cerebral Infarction; Drug Evaluation, Preclinical; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Fibrinogen; Focal Adhesion Kinase 1; Infarction, Middle Cerebral Artery; Integrin alphaVbeta3; Male; Models, Animal; Nerve Tissue Proteins; Neuroprotective Agents; Peptides, Cyclic; Phosphorylation; Protein Processing, Post-Translational; Random Allocation; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2006 |
Cathepsin and calpain inhibitor E64d attenuates matrix metalloproteinase-9 activity after focal cerebral ischemia in rats.
Topics: Animals; Blood-Brain Barrier; Brain Edema; Calpain; Cathepsin B; Cerebral Hemorrhage; Cysteine Proteinase Inhibitors; Drug Evaluation, Preclinical; Enzyme Activation; Enzyme Induction; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Infarction, Middle Cerebral Artery; Leucine; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Nerve Tissue Proteins; Neuroprotective Agents; Premedication; Rats; Rats, Sprague-Dawley; Reperfusion; Single-Blind Method | 2006 |
Matrix metalloproteinase-mediated disruption of tight junction proteins in cerebral vessels is reversed by synthetic matrix metalloproteinase inhibitor in focal ischemia in rat.
Topics: Animals; Astrocytes; Blood-Brain Barrier; Blotting, Western; Brain Ischemia; Cerebral Arteries; Cerebral Veins; Claudin-5; Endothelial Cells; Enzyme Activators; Evans Blue; Furin; Gelatinases; Immunohistochemistry; Infarction, Middle Cerebral Artery; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Membrane Proteins; Nerve Tissue Proteins; Occludin; Protease Inhibitors; Rats; Rats, Inbred SHR; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sucrose; Tight Junctions | 2007 |
Melatonin decreases neurovascular oxidative/nitrosative damage and protects against early increases in the blood-brain barrier permeability after transient focal cerebral ischemia in mice.
Topics: Animals; Blood-Brain Barrier; Brain; Evans Blue; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Laser-Doppler Flowmetry; Male; Melatonin; Mice; Mice, Inbred C57BL; Permeability; Reactive Nitrogen Species; Reactive Oxygen Species; Reperfusion Injury | 2006 |
Use of TTC staining for the evaluation of tissue injury in the early phases of reperfusion after focal cerebral ischemia in rats.
Topics: Animals; Brain Ischemia; Coloring Agents; Evans Blue; Fluoresceins; Fluorescent Dyes; Indoles; Infarction, Middle Cerebral Artery; Male; Microscopy, Electron; Middle Cerebral Artery; Myocardium; Organic Chemicals; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tetrazolium Salts | 2006 |
Inhibition of integrin alphavbeta3 reduces blood-brain barrier breakdown in focal ischemia in rats.
Topics: Analysis of Variance; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Blood-Brain Barrier; Blotting, Western; Brain Edema; Disease Models, Animal; Evans Blue; Fibrinogen; Gene Expression Regulation; Granulocyte Colony-Stimulating Factor; Immunohistochemistry; Infarction, Middle Cerebral Artery; Integrin alphaVbeta3; Interleukin-3; Male; Neurologic Examination; Peptides, Cyclic; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Recombinant Proteins; Tetraspanin 30; Vascular Endothelial Growth Factor A | 2006 |
Relative distribution of plasma flow markers and red blood cells across BBB openings in acute cerebral ischemia.
Topics: Albumins; Animals; Biomarkers; Blood-Brain Barrier; Brain Ischemia; Cerebral Arteries; Cerebrovascular Circulation; Dextrans; Erythrocytes; Evans Blue; Fluorescein-5-isothiocyanate; Infarction, Middle Cerebral Artery; Male; Microcirculation; Microscopy, Confocal; Plasma; Predictive Value of Tests; Rats; Rats, Wistar | 2007 |
Erythropoietin prevents blood brain barrier damage induced by focal cerebral ischemia in mice.
Topics: Animals; Blood-Brain Barrier; Brain Edema; Cerebrovascular Circulation; Down-Regulation; Erythropoietin; Evans Blue; Fluorescent Antibody Technique; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Male; Membrane Proteins; Mice; Microscopy, Confocal; Occludin; Recombinant Proteins; Stroke; Vascular Endothelial Growth Factor Receptor-2 | 2007 |
Effect of aminoguanidine on post-ischemic brain edema in transient model of focal cerebral ischemia.
Topics: Animals; Blood-Brain Barrier; Brain Edema; Brain Infarction; Cerebral Arteries; Coloring Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Inhibitors; Evans Blue; Guanidines; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Male; Rats; Rats, Wistar; Reperfusion Injury; Time Factors; Treatment Outcome | 2007 |
Acute leakage patterns of fluorescent plasma flow markers after transient focal cerebral ischemia suggest large openings in blood-brain barrier.
Topics: Albumins; Animals; Blood-Brain Barrier; Cerebrovascular Circulation; Coloring Agents; Dextrans; Evans Blue; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Male; Microcirculation; Rats; Rats, Wistar; Reperfusion Injury | 2008 |
Early appearance of activated matrix metalloproteinase-9 and blood-brain barrier disruption in mice after focal cerebral ischemia and reperfusion.
Topics: Animals; Benzyl Compounds; Blood-Brain Barrier; Blotting, Western; Collagen; Collagenases; Coloring Agents; Dexamethasone; Drug Combinations; Enzyme Inhibitors; Evans Blue; Gelatinases; Immunohistochemistry; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Male; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Pentoxifylline; Reperfusion Injury; Succinates; Tissue Inhibitor of Metalloproteinase-1 | 1999 |
Role of endothelial nitric oxide generation and peroxynitrite formation in reperfusion injury after focal cerebral ischemia.
Topics: Animals; Biomarkers; Blood-Brain Barrier; Coloring Agents; Endothelium, Vascular; Enzyme Inhibitors; Evans Blue; Indazoles; Infarction, Middle Cerebral Artery; Matrix Metalloproteinase 9; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxidants; Permeability; Reperfusion Injury; Tyrosine | 2000 |