euphorbia-factor-l1 and Melanoma

Euphorbia factor L1 (EFL1), a lathyrane-type diterpenoid from the medicinal herb Euphorbia lathyris L., has been documented to possess various pharmacologic actives. However, the function of EFL1 on breast cancer is not clear. In this study, we explored the effect and mechanism of EFL1 on breast cancer liver metastasis. Female BALB/c mice were subjected to breast cancer-surgical hepatic implantation (SHI) to establish breast cancer liver metastasis model

Topics: Animals; Ascites; Diterpenes; Female; Liver Neoplasms; Melanoma; Melanoma, Cutaneous Malignant; Mice; Neoplasms, Second Primary