eucalyptol has been researched along with Disease Models, Animal in 29 studies
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The monoterpene oxide, 1,8-cineole (cineole, eucalyptol) was examined for its possible influence on the acute phase of trinitrobenzene sulfonic acid (TNBS)-induced colitis in rats." | 7.72 | 1,8-cineole (eucalyptol), a monoterpene oxide attenuates the colonic damage in rats on acute TNBS-colitis. ( Campos, AR; De Araújo, RP; Lima Júnior, RC; Rao, VS; Santos, FA; Silva, RM, 2004) |
| "Most chronic diseases are caused by chronic inflammation and oxidative stress as well as harmful factors." | 6.53 | Eucalyptol and Its Role in Chronic Diseases. ( Kim, KY; Seol, GH, 2016) |
| "Eucalyptol is an active compound of eucalyptus essential oil and was reported to have many medical attributes including cytotoxic effect on breast cancer cells." | 4.02 | Physicochemical characterization, cytotoxic effect and toxicity evaluation of nanostructured lipid carrier loaded with eucalyptol. ( Abdullah, R; Alitheen, NB; Aziz, MNM; Hussin, Y; Izham, MNM; Masarudin, MJ; Mohamad, NE; Rahim, NFC; Rahman, HS; Yeap, SK, 2021) |
| "This study aimed to evaluate potential protecting effect of ML and its major constituent, eucalyptol, against acetic acid-induced colitis in rats, a model of human inflammatory bowel disease (IBD)." | 3.83 | Mentha longifolia protects against acetic-acid induced colitis in rats. ( Abdallah, HM; Ali, SS; Murad, HA, 2016) |
| " The acetic acid-induced gastric ulcer model and Western Blot assay (COX-2 and EGF) were also used to evaluate the OEH healing capacity." | 3.77 | Gastroprotective and ulcer healing effects of essential oil from Hyptis spicigera Lam. (Lamiaceae). ( de Almeida, AC; de-Faria, FM; Dunder, RJ; Hiruma-Lima, CA; Luiz-Ferreira, A; Manzo, LP; Pellizzon, CH; Rehen, CS; Rozza, AL; Salvador, MJ; Socca, EA; Souza-Brito, AR; Takayama, C; Valim-Araújo, Dde A, 2011) |
| "The monoterpene oxide, 1,8-cineole (cineole, eucalyptol) was examined for its possible influence on the acute phase of trinitrobenzene sulfonic acid (TNBS)-induced colitis in rats." | 3.72 | 1,8-cineole (eucalyptol), a monoterpene oxide attenuates the colonic damage in rats on acute TNBS-colitis. ( Campos, AR; De Araújo, RP; Lima Júnior, RC; Rao, VS; Santos, FA; Silva, RM, 2004) |
| "Most chronic diseases are caused by chronic inflammation and oxidative stress as well as harmful factors." | 2.53 | Eucalyptol and Its Role in Chronic Diseases. ( Kim, KY; Seol, GH, 2016) |
| "Using the experimental cerebral malaria model, treatment of infected mice for 6 consecutive days with 100 mg/kg/day 1,8-cineole reduced cerebral edema with a 50% reduction in parasitemia." | 1.72 | The monoterpene 1,8-cineole prevents cerebral edema in a murine model of severe malaria. ( Caruso-Neves, C; Coelho-de-Souza, AN; Leal-Cardoso, JH; Miranda, KR; Peruchetti, DB; Pinheiro, AAS; Pinheiro, AS; Santos, ECD; Silva, LS; Silva-Aguiar, RP; Teixeira, DE; Wendt, CHC, 2022) |
| "Flurbiprofen (FP) is one of the most potent nonsteroidal anti-inflammatory drugs with very low bioavailability of approximately 12% following transdermal administration, compared to that after oral administration." | 1.56 | Development of galangal essential oil-based microemulsion gel for transdermal delivery of flurbiprofen: simultaneous permeability evaluation of flurbiprofen and 1,8-cineole. ( Chen, J; Dong, J; Dong, YF; Feng, H; Gu, W; Wu, FY; Yang, BQ; Zhu, XM, 2020) |
| "Treatment with eucalyptol attenuated ciliated cell damage in cigarette smoke-exposed lungs." | 1.51 | Eucalyptol protects lungs against bacterial invasion through attenuating ciliated cell damage and suppressing MUC5AC expression. ( Dai, B; He, M; Kang, J; Su, XM; Sun, YT; Yu, N, 2019) |
| "As an intractable health threat, neuropathic pain is now a key problem in clinical therapy, which can be caused by lesions affecting the peripheral nervous systems." | 1.51 | Effects of 1,8-cineole on neuropathic pain mediated by P2X2 receptor in the spinal cord dorsal horn. ( Gao, Y; Li, Q; Liu, YG; Liu, ZX; Wang, XD; Yang, BL; Zhang, YL; Zheng, XB; Zhou, CF; Zhu, GC, 2019) |
| "Its effect on LPS-induced pulmonary inflammation was associated with suppression of TLR4 and NF-κB expressions." | 1.40 | 1,8-cineol attenuates LPS-induced acute pulmonary inflammation in mice. ( Fang, C; Sun, J; Tang, F; Zhao, C, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (17.24) | 29.6817 |
| 2010's | 12 (41.38) | 24.3611 |
| 2020's | 12 (41.38) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Wang, Y | 1 |
| Zhang, X | 1 |
| Fu, Y | 1 |
| Fu, D | 1 |
| Zhen, D | 1 |
| Xing, A | 1 |
| Chen, Y | 1 |
| Gong, G | 1 |
| Wei, C | 1 |
| Izham, MNM | 1 |
| Hussin, Y | 1 |
| Rahim, NFC | 1 |
| Aziz, MNM | 1 |
| Yeap, SK | 1 |
| Rahman, HS | 1 |
| Masarudin, MJ | 1 |
| Mohamad, NE | 1 |
| Abdullah, R | 1 |
| Alitheen, NB | 1 |
| Abdallah, HMI | 1 |
| El Awdan, SA | 1 |
| Abdel-Rahman, RF | 1 |
| Farrag, ARH | 1 |
| Allam, RM | 1 |
| Alves-Silva, JM | 1 |
| Zuzarte, M | 1 |
| Marques, C | 1 |
| Viana, S | 1 |
| Preguiça, I | 1 |
| Baptista, R | 1 |
| Ferreira, C | 1 |
| Cavaleiro, C | 1 |
| Domingues, N | 1 |
| Sardão, VA | 1 |
| Oliveira, PJ | 1 |
| Reis, F | 1 |
| Salgueiro, L | 1 |
| Girão, H | 1 |
| Santos, ECD | 1 |
| Silva, LS | 1 |
| Pinheiro, AS | 1 |
| Teixeira, DE | 1 |
| Peruchetti, DB | 1 |
| Silva-Aguiar, RP | 1 |
| Wendt, CHC | 1 |
| Miranda, KR | 1 |
| Coelho-de-Souza, AN | 1 |
| Leal-Cardoso, JH | 1 |
| Caruso-Neves, C | 1 |
| Pinheiro, AAS | 1 |
| Liu, FL | 1 |
| Rong, Y | 1 |
| Zhou, H | 1 |
| Yu, T | 1 |
| Liu, L | 1 |
| Cao, Q | 1 |
| Qin, Z | 1 |
| Qu, L | 1 |
| Liao, X | 1 |
| Jiang, Q | 1 |
| Zhang, N | 1 |
| Xu, X | 1 |
| Dong, J | 1 |
| Zhu, XM | 1 |
| Wu, FY | 1 |
| Yang, BQ | 1 |
| Feng, H | 1 |
| Dong, YF | 1 |
| Gu, W | 1 |
| Chen, J | 1 |
| Chen, CH | 1 |
| Chen, HC | 1 |
| Chang, WT | 1 |
| Lee, MS | 1 |
| Liu, YC | 1 |
| Lin, MK | 1 |
| Al-Okbi, SY | 1 |
| Amin, MA | 1 |
| Mohamed, AEA | 1 |
| Edris, AE | 1 |
| Sharaf, OM | 1 |
| Mabrok, HB | 1 |
| Ramadan, AA | 1 |
| Nakamura, T | 1 |
| Yoshida, N | 1 |
| Yamanoi, Y | 1 |
| Honryo, A | 1 |
| Tomita, H | 1 |
| Kuwabara, H | 1 |
| Kojima, Y | 1 |
| Xu, G | 1 |
| Guo, J | 1 |
| Sun, C | 1 |
| Yu, N | 1 |
| Sun, YT | 1 |
| Su, XM | 1 |
| He, M | 1 |
| Dai, B | 1 |
| Kang, J | 1 |
| Oliveira-Tintino, CDM | 1 |
| Pessoa, RT | 1 |
| Fernandes, MNM | 1 |
| Alcântara, IS | 1 |
| da Silva, BAF | 1 |
| de Oliveira, MRC | 1 |
| Martins, AOBPB | 1 |
| da Silva, MDS | 1 |
| Tintino, SR | 1 |
| Rodrigues, FFG | 1 |
| da Costa, JGM | 1 |
| de Lima, SG | 1 |
| Kerntopf, MR | 2 |
| da Silva, TG | 1 |
| de Menezes, IRA | 1 |
| Zheng, XB | 1 |
| Zhang, YL | 1 |
| Li, Q | 1 |
| Liu, YG | 1 |
| Wang, XD | 1 |
| Yang, BL | 1 |
| Zhu, GC | 1 |
| Zhou, CF | 1 |
| Gao, Y | 1 |
| Liu, ZX | 1 |
| Zhao, C | 1 |
| Sun, J | 1 |
| Fang, C | 1 |
| Tang, F | 1 |
| Ahad, A | 1 |
| Aqil, M | 1 |
| Ali, A | 1 |
| Kim, KY | 2 |
| Lee, HS | 2 |
| Seol, GH | 2 |
| Park, DE | 1 |
| Song, WJ | 1 |
| Park, HW | 1 |
| Kang, HR | 1 |
| Cho, SH | 1 |
| Sohn, SW | 1 |
| Murad, HA | 1 |
| Abdallah, HM | 1 |
| Ali, SS | 1 |
| Kennedy-Feitosa, E | 1 |
| Okuro, RT | 1 |
| Pinho Ribeiro, V | 1 |
| Lanzetti, M | 1 |
| Barroso, MV | 1 |
| Zin, WA | 1 |
| Porto, LC | 1 |
| Brito-Gitirana, L | 1 |
| Valenca, SS | 1 |
| Nascimento, NR | 1 |
| Refosco, RM | 1 |
| Vasconcelos, EC | 1 |
| Santos, CF | 1 |
| Batista, FJ | 1 |
| De Sousa, CM | 1 |
| Fonteles, MC | 1 |
| Inoue, K | 1 |
| Takano, H | 1 |
| Takayama, C | 1 |
| de-Faria, FM | 1 |
| de Almeida, AC | 1 |
| Valim-Araújo, Dde A | 1 |
| Rehen, CS | 1 |
| Dunder, RJ | 1 |
| Socca, EA | 1 |
| Manzo, LP | 1 |
| Rozza, AL | 1 |
| Salvador, MJ | 1 |
| Pellizzon, CH | 1 |
| Hiruma-Lima, CA | 1 |
| Luiz-Ferreira, A | 1 |
| Souza-Brito, AR | 1 |
| Santos, FA | 3 |
| Silva, RM | 2 |
| Campos, AR | 1 |
| De Araújo, RP | 1 |
| Lima Júnior, RC | 1 |
| Rao, VS | 3 |
| Tomé, AR | 1 |
| Pompeu, MM | 1 |
| Teixeira, MJ | 1 |
| De Freitas, LA | 1 |
| De Souza, VL | 1 |
| Yu, D | 1 |
| Pearson, SK | 1 |
| Bowen, WH | 1 |
| Luo, D | 1 |
| Kohut, BE | 1 |
| Harper, DS | 1 |
1 review available for eucalyptol and Disease Models, Animal
| Article | Year |
|---|---|
Eucalyptol and Its Role in Chronic Diseases.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Chronic Disease; Cyclohexanols; Disease Models, Ani | 2016 |
28 other studies available for eucalyptol and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
1, 8-cineole protects against ISO-induced heart failure by inhibiting oxidative stress and ER stress in vitro and in vivo.
Topics: Animals; Apoptosis; Cell Line; Disease Models, Animal; Endoplasmic Reticulum Stress; Eucalyptol; Hea | 2021 |
Physicochemical characterization, cytotoxic effect and toxicity evaluation of nanostructured lipid carrier loaded with eucalyptol.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Eucalypt | 2021 |
1,8 Cineole and Ellagic acid inhibit hepatocarcinogenesis via upregulation of MiR-122 and suppression of TGF-β1, FSCN1, Vimentin, VEGF, and MMP-9.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Carrier Proteins; Disease Models, Animal; | 2022 |
1,8-Cineole ameliorates right ventricle dysfunction associated with pulmonary arterial hypertension by restoring connexin43 and mitochondrial homeostasis.
Topics: Animals; Cardiomyopathies; Connexin 43; Disease Models, Animal; Eucalyptol; Heart Ventricles; Homeos | 2022 |
The monoterpene 1,8-cineole prevents cerebral edema in a murine model of severe malaria.
Topics: Animals; Antimalarials; Brain Edema; Disease Models, Animal; Endothelial Cells; Eucalyptol; Malaria, | 2022 |
Cineole inhibits the biosynthesis of leukotrienes and prostaglandins to alleviate allergic rhinitis: Insights from metabolomics.
Topics: Animals; Arachidonic Acid; Chromatography, Liquid; Cytokines; Disease Models, Animal; Eucalyptol; Im | 2023 |
Development of galangal essential oil-based microemulsion gel for transdermal delivery of flurbiprofen: simultaneous permeability evaluation of flurbiprofen and 1,8-cineole.
Topics: Administration, Cutaneous; Alpinia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Cur | 2020 |
Magnoliae Flos Essential Oil as an Immunosuppressant in Dendritic Cell Activation and Contact Hypersensitivity Responses.
Topics: Adaptive Immunity; Animals; Camphor; Cells, Cultured; Cytokines; Dendritic Cells; Dermatitis, Contac | 2020 |
Basil Essential Oil and Its Nanoemulsion Mitigate Non Alcoholic Steatohepatitis in Rat Model with Special Reference to Gut Microbiota.
Topics: Acyclic Monoterpenes; Administration, Oral; Animals; Disease Models, Animal; Emulsions; Eucalyptol; | 2020 |
Eucalyptus oil reduces allergic reactions and suppresses mast cell degranulation by downregulating IgE-FcεRI signalling.
Topics: Animals; Bone Marrow Cells; Calcium; Cell Degranulation; Chemokines; Disease Models, Animal; Down-Re | 2020 |
Eucalyptol ameliorates early brain injury after subarachnoid haemorrhage via antioxidant and anti-inflammatory effects in a rat model.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Brain Injuries; Cytokines; Disease Model | 2021 |
Eucalyptol protects lungs against bacterial invasion through attenuating ciliated cell damage and suppressing MUC5AC expression.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Bacterial Load; Cilia; Disease Models, Animal; Down-Regula | 2019 |
Anti-inflammatory and anti-edematogenic action of the Croton campestris A. St.-Hil (Euphorbiaceae) essential oil and the compound β-caryophyllene in in vivo models.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Carrageenan; Croton; Cyclohexano | 2018 |
Effects of 1,8-cineole on neuropathic pain mediated by P2X2 receptor in the spinal cord dorsal horn.
Topics: Administration, Oral; Animals; Behavior Observation Techniques; Disease Models, Animal; Eucalyptol; | 2019 |
1,8-cineol attenuates LPS-induced acute pulmonary inflammation in mice.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Cyclohexanols; D | 2014 |
Investigation of antihypertensive activity of carbopol valsartan transdermal gel containing 1,8-cineole.
Topics: Acrylic Resins; Administration, Cutaneous; Animals; Antihypertensive Agents; Blood Pressure; Chemist | 2014 |
Eucalyptol suppresses matrix metalloproteinase-9 expression through an extracellular signal-regulated kinase-dependent nuclear factor-kappa B pathway to exert anti-inflammatory effects in an acute lung inflammation model.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Cyclohexanols; Cytokines; Dexamethasone; Disea | 2015 |
Effect of 1.8-Cineole in Dermatophagoides pteronyssinus-Stimulated Bronchial Epithelial Cells and Mouse Model of Asthma.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cell Line; Cell Survival; Cyclohexanols; Cytokines; D | 2016 |
Mentha longifolia protects against acetic-acid induced colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Colitis; Colon; Cyclohexan | 2016 |
Eucalyptol attenuates cigarette smoke-induced acute lung inflammation and oxidative stress in the mouse.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cyclohexanols; Disease Models, Animal; Dose-Respons | 2016 |
1,8-Cineole induces relaxation in rat and guinea-pig airway smooth muscle.
Topics: Animals; Bronchi; Bronchodilator Agents; Cyclohexanols; Disease Models, Animal; Dose-Response Relati | 2009 |
Therapeutic effects of inhaled 1,8-cineole on allergic airway inflammation.
Topics: Animals; Anti-Inflammatory Agents; Cyclohexanols; Disease Models, Animal; Eucalyptol; Guinea Pigs; I | 2011 |
Gastroprotective and ulcer healing effects of essential oil from Hyptis spicigera Lam. (Lamiaceae).
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Bicyclic Monoterpenes; Brazil; Bridged Bicyclo Compounds; C | 2011 |
1,8-cineole (eucalyptol), a monoterpene oxide attenuates the colonic damage in rats on acute TNBS-colitis.
Topics: Acute Disease; Administration, Rectal; Animals; Anti-Inflammatory Agents; Colitis; Colon; Cyclohexan | 2004 |
1,8-cineol, a food flavoring agent, prevents ethanol-induced gastric injury in rats.
Topics: Administration, Oral; Alcoholism; Animals; Antioxidants; Cyclohexanols; Disease Models, Animal; Drug | 2001 |
1,8-cineole protects against liver failure in an in-vivo murine model of endotoxemic shock.
Topics: Animals; Cyclohexanols; Disease Models, Animal; Eucalyptol; Galactosamine; Lipopolysaccharides; Live | 2001 |
Caries inhibition efficacy of an antiplaque/antigingivitis dentifrice.
Topics: Analysis of Variance; Animals; Anti-Infective Agents, Local; Cariostatic Agents; Cyclohexanols; Dent | 2000 |