Compounds > etoposide
Page last updated: 2024-08-23

etoposide and Osteosarcoma

etoposide has been researched along with Osteosarcoma in 118 studies

Research

Studies (118)

TimeframeStudies, this research(%)All Research%
pre-19901 (0.85)18.7374
1990's27 (22.88)18.2507
2000's38 (32.20)29.6817
2010's43 (36.44)24.3611
2020's9 (7.63)2.80

Authors

AuthorsStudies
Adachi, S; Hiramatsu, H; Kato, I; Mizowaki, T; Nakamoto, Y; Okamoto, T; Saida, S; Sakamoto, A; Shimizu, H; Takita, J; Taura, K; Umeda, K; Uto, M1
Adamczyk-Grochala, J; Betlej, G; Błoniarz, D; Lewińska, A; Rzeszutek, I; Wnuk, M1
Adachi, S; Akazawa, R; Arakawa, Y; Hiramatsu, H; Kato, I; Moritake, H; Okamoto, T; Saida, S; Sakamoto, A; Sumiyoshi, S; Takita, J; Umeda, K1
Adam, J; Bayle, A; Briand, S; Chamseddine, AN; Court, C; Dômont, J; Dumont, SN; Even, C; Faron, M; Haddag-Miliani, L; Honoré, C; Lazure, T; Le Cesne, A; Levy, A; Lucibello, F; Mir, O; Ngo, C; Perret, A; Verret, B1
Brownridge, PJ; Campbell, AE; Corbin, EK; Eyers, CE; Ferraz Franco, C; Jones, AR; Kalyuzhnyy, A; Perkins, ND; Perkins, S; Su, LI1
Cameron, AL; Elliss-Brookes, L; Fardus-Reid, F; Feltbower, RG; Fern, L; Fraser, J; Irvine, L; McCabe, MG; Pritchard-Jones, K; Shelton, J; Stiller, C; Wills, L1
Bautista, F; Campbell-Hewson, Q; Gaspar, N; Huang, J; Okpara, CE1
Bohlman, S; Manfredi, JJ; Senturk, JC1
Duan, R; Li, C; Wang, F; Yangi, JC1
Choisunirachon, N; Kok, MK; Nakagawa, T; Nishimura, R; Ong, SM; Saeki, K; Tanaka, Y; Yoshitake, R1
Bompas, E; Bouvier, C; Brisse, HJ; Brugieres, L; Castex, MP; Cheurfa, N; Corradini, N; Delaye, J; Entz-Werlé, N; Gaspar, N; Gentet, JC; Italiano, A; Le Deley, MC; Lervat, C; Marec-Berard, P; Mascard, E; Occean, BV; Pacquement, H; Piperno-Neumann, S; Redini, F; Saumet, L; Schmitt, C; Tabone, MD; Verite-Goulard, C1
Almeida, L; Coutinho, L; Fernandes, E; Ferreira de Oliveira, JMP; Oliveira, H; Pacheco, AR; Pinho, S; Santos, C1
Dong, Y; Jiang, S; Wang, G1
Nakagawa, T; Nishimura, R; Ong, SM; Saeki, K; Tanaka, Y; Yamamoto, H; Yoshitake, R1
Azmy, V; Brooks, JP; Hsu, FI; Luon, D; Price, C; Prozora, SD; Thompson, A1
Burchill, SA; Jabri, S; Roundhill, EA1
Abboud, MR; Abou Ali, B; Akel, S; Boulos, F; El-Solh, H; Ghanem, KM; Haidar, R; Muwakkit, SA; Saab, R; Saghieh, S; Salman, M; Tamim, H1
Bajpai, J; Banavali, S; Chandrasekharan, A; Ghosh, J; Gupta, S; Hingmare, S; Mandal, T; Rangarajan, B; Rekhi, B; Shah, K; Shetty, N; Simha, V; Vora, T1
Anract, P; Bertucci, F; Blay, JY; Bompas, E; Brugieres, L; Collard, O; Cupissol, D; de Pinieux, G; Delaye, J; Duffaud, F; Italiano, A; Laurence, V; Le Cesne, A; Le Deley, MC; Occean, BV; Penel, N; Perrin, C; Piperno-Neumann, S; Ray-Coquard, I; Rios, M1
Kok, MK; Nakagawa, T; Nishimura, R; Ong, SM; Saeki, K1
Jin, S; Qi, SN; Yang, TM; Yang, YJ; Yuan, HQ; Zhang, B; Zhao, N1
Arai, E; Futamura, N; Hirata, A; Ishiguro, N; Kozawa, E; Miyahara, R; Nishida, Y; Tsukushi, S; Tsurudome, I; Urakawa, H1
Bar-Sela, G; Miller, RC; Novotny, PJ; Sio, TT; Sohawon, S; Thariat, J; Van Houtte, P; Vu, CC1
Ellis, D; Necessary, CA; Roffwarg, D1
Fu, WM; Hsieh, IS; Yang, RS1
Wang, W; Wang, Z; Xiao, X1
Anninga, J; Bernstein, M; Bielack, SS; Böhling, T; Butterfass-Bahloul, T; Calaminus, G; Capra, M; Deffenbaugh, C; Dhooge, C; Eriksson, M; Flanagan, AM; Gelderblom, H; Goorin, A; Gorlick, R; Gosheger, G; Grimer, RJ; Hall, KS; Helmke, K; Hogendoorn, PC; Hook, JM; Jovic, G; Jundt, G; Kager, L; Krailo, M; Kuehne, T; Lau, CC; Letson, GD; Marina, N; Meyer, J; Meyers, PA; Morris, C; Mottl, H; Nadel, H; Nagarajan, R; Randall, RL; Schomberg, P; Schwarz, R; Smeland, S; Sydes, MR; Teot, LA; Whelan, JS1
Benassi, MS; Conti, A; Novello, C; Pazzaglia, L; Perego, P; Picci, P; Pollino, S; Quattrini, I1
Anurathapan, U; Choeyprasert, W; Chuansumrit, A; Hongeng, S; Nartthanarung, A; Pakakasama, S; Sirachainan, N; Songdej, D1
Wang, B; Xu, M; Xu, SF; Yu, XC1
Ahn, HS; Hong, CR; Ju, HY; Kang, HJ; Kim, H; Kim, HS; Kim, MS; Lee, JW; Park, JD; Park, KD; Park, SH; Shin, HY1
Bo, Q; Li, J; Li, K; Li, X; Liu, T; Tian, J; Wang, H1
Abriola, L; Fernandez, RJ; Glazer, PM; Hoyer, D; Hungerford, W; Liu, Y; Merkel, J; Peterson-Roth, E; Pike, LR; Qian, JM; Stachelek, GC1
Ash, S; Cohen, IJ; Issakov, J; Kollender, Y; Shkalim-Zemer, V; Toledano, H; Yaniv, I1
Bakhshi, S; Batra, A; Khan, SA; Nataraj, V; Rastogi, S; Sharma, MC; Vishnubhatla, S1
Bernstein, ML; Devidas, M; Gebhardt, MC; Goorin, AM; Grier, HE; Healey, JH; Krailo, MD; Lipshultz, SE; Meyers, PA; Sato, JK; Schwartz, CL; Steinherz, LJ; Teot, LA; Wexler, LH1
Ferrari, S; Serra, M1
Azuma, E; Hirayama, M; Imai, H; Iwamoto, S; Komada, Y; Matsumine, A; Miura, Y; Nakatani, K; Toyoda, H; Yodoya, N1
Nakagawa, T; Nishimura, R; Ong, SM; Saeki, K; Tanaka, Y1
Delebinski, C; Eggert, A; Jaeger, S; Kauczor, G; Kleinsimon, S; Seifert, G1
Almeida, L; Coutinho, L; Ferreira de Oliveira, JM; Oliveira, H; Pacheco, AR; Pimentel, F; Santos, C1
Arndt, CA; Hawkins, DS; Hoots, WK; Inwards, CY; Kleinerman, ES; Koshkina, NV; Morales-Arias, JA; Munsell, MF; Rodriguez, NI1
Bohr, VA; Christmann, M; Gestrich, C; Kaina, B; Roos, WP; Tomicic, MT1
Adalberto, Bdel P; Aglietta, M; Aliberti, S; Berger, M; Biasin, E; Brach del Prever, A; Eleonora, B; Fagioli, F; Ferrari, S; Franca, F; Francesco, S; Giovanni, G; Grignani, G; Massimo, A; Massimo, B; Saglio, F; Sandra, A; Stefano, F1
Hayashi, K; Kimura, H; Nishida, H; Ohnari, I; Shirai, T; Takeuchi, A; Tomita, K; Tsuchiya, H1
Aliev, MD; Chernov, IS; Machak, GN; Meluzova, OM; Polotskiĭ, BE1
Buchbinder, D; Casillas, J; Linetsky, M; Steinberg, G1
Gan, M; Mao, N; Shi, Q; Yang, H; Zhu, X; Zou, J1
Ambroszkiewicz, J; Chełchowska, M; Gajewska, J; Klepacka, T; Laskowska-Klita, T; Woźniak, W1
Brookes, KE; Dive, C; Holt, SV; Makin, GW1
Chin, C; Midulla, P; Shapiro, M; Wistinghausen, B1
Gafton, GI; Gudz', IuV; Ivanova, TV; Krzhivitskiĭ, PI; Kupatadze, DD; Lazareva, IuR; Levchenko, EV; Nabokov, VV; Novik, VI; Petrov, VG; Punanov, IuA; Safonova, SA1
Ishii, Y; Kumita, S; Kuribayashi, S; Matsuno, A; Yamada, S; Yamada, SM1
Feng, DP; Gong, WH; Huang, T; Jiang, GJ; Li, XC; Li, XH; Zou, CP1
Ding, HM; Gu, ZP; Li, D; Wang, ZY; Wei, JJ; Yan, SC; Yang, YJ; Yao, C1
Agata, M; Kato, M; Nakayama, M; Yoshida, K1
Boulares, AH; Sherif, ZA; Smulson, ME; Yakovlev, AG; Zoltoski, AJ1
Bacci, G; Longhi, A; Macchiagodena, M; Vitali, G1
Cook, JL; Iklé, DN; Lewis, AM; Miura, TA; Routes, JM1
Chang, TT; Chang, WH; Chen, RL; Hsiao, TC; Hung, IJ; Lin, DT; Lin, KH; Lin, KS; Lin, MT; Lu, MY; Shu, SG; Wu, CT; Yang, CP; Yang, RS1
Bouralexis, S; Evdokiou, A; Findlay, DM; Hay, S; Labrinidis, A1
Debatin, KM; Fulda, S; Hotfilder, M; Poremba, C; Schäfer, KL; Truckenbrod, B; Van Valen, F; Winkelmann, W1
Li, FB; Liao, WM; Liu, ZC; Zhou, JM; Zhu, JJ; Zhu, XF1
Guo, W; Li, DS; Tang, S; Tang, XD; Yang, RL; Yang, Y1
Ikarashi, Y; Imai, C; Kakihara, T; Tanaka, A; Uchiyama, M; Watanabe, A1
Batchelor, AG; Liddington, MI; Rawlins, JM; Towns, G1
Agner, J; Bartek, J; Falck, J; Lukas, J1
Berta, M; Bertoni, F; del Prever, AB; Fagioli, F; Ferrari, S; Mercuri, M1
Díaz-Montero, CM; McIntyre, BW1
Brodsky, I; Rosenbluth, JZ; Styler, MJ; Zak, D1
Lewis, I; McTiernan, A; Meyer, T; Michelagnoli, MP; Whelan, JS1
Dai, J; Guo, Y; Jin, J; Shi, M; Wang, R; Wu, M; Zhang, X; Zhao, J1
Li, FB; Liao, WM; Zhu, JJ; Zhu, XF1
Imoto, I; Inazawa, J; Katsuki, Y; Mizutani, S; Nagasawa, M; Nakada, S; Yokoyama, T1
Fukasawa, K; Izumi, M; Kamiyama, J; Kawa, S; Maruyama, S; Nikaido, T; Sakai, T; Sukenaga, Y; Takahara, Y; Wakada, M; Watanabe, N; Yogosawa, S; Yokoyama, H; Yoshizawa, K; Zhang, H1
Guo, W; Tang, S; Tang, XD; Yang, Y1
Brugières, L; Dupoüy, N; Entz-Werlé, N; Gentet, JC; Guinebretière, JM; Kalifa, C; Le Deley, MC; Marec-Bérard, P; Pacquement, H; Pichon, F; Schmitt, C; Tabone, MD; Vanel, D1
Baker, LH; Blumberg, B; Giordano, TJ; Hollenberg, PF; Hughes, DP; Larios, JM; Lizyness, ML; Mensah-Osman, EJ; Rae, JM; Tabb, MM; Thomas, DG1
Alimirah, F; Chen, J; Choubey, D; Ho, SM; Panchanathan, R; Zhang, X1
Chen, ZX; Deng, R; Fan, Q; Feng, GK; He, AS; Huang, XF; Liang, SG; Liao, WM; Sheng, PY; Yang, ZB; Yuan, XW; Zhu, XF1
Anderson, P; Chang, EL; Herzog, CE; Hughes, D; Huh, W; Kornguth, DG; Mahajan, A; Pelloski, CE; Woo, SY1
Bacon, C; Egerer, G; Freier, K; Hofele, CM; Thiele, OC1
Almasan, A; Banerjee, D; Bertino, JR; Fan, J; Hochhauser, D; Kelly, R; Li, W; Wahl, GM; Yin, Y; Zielinski, Z1
Carpentier, AF; Chantelard, JV; Henin, D; Poisson, M1
Cowie, FJ; Dick, G; Flanagan, RJ; Judson, I; McCarthy, PT; Phillips, M; Pinkerton, CR1
Elomaa, I1
Ayass, M; Cassano, W; Dickson, N; Enneking, W; Graham-Pole, J; Heare, M; Heare, T; Marcus, R; Saleh, R; Spanier, S1
Donaldson, SS; Ensign, LG; Heyn, R; Khan, F; Maurer, HM; Ruymann, F; Smith, MA; Vietti, T1
Bacci, G; Battistini, A; Ferrari, S; Orlandi, M; Puggioli, C; Sassoli, V; Strazzari, S1
Carstens, C; Lowry, PA1
Avet-Loiseau, H; Berger, C; Bernard, JL; Brunat-Mentigny, M; De Lumley, L; Demaille, MC; Gentet, JC; Kalifa, C; Pacquement, H; Pein, F; Pillon, P; Sariban, E; Schmitt, C1
Agata, H; Fujimoto, T; Hamaguchi, N; Hirota, T; Iwata, A; Katano, N; Kitagawa, S; Kobayashi, S; Konno, K; Sato, T; Sawada, K; Takeuchi, M1
Ben Arush, MW; Drumea, K; Haim, N; Kuten, A; Meller, I; Moses, M; Stein, ME1
Bacci, G; Bertoni, F; Briccoli, A; Campanacci, M; Cesari, M; Fabbri, N; Ferrari, S; Forni, C; Gasbarrini, A; Mercuri, M1
Benjamin, RS; Gano, J; Gianan, MA; Jaffe, N; Jia, SF; Kleinerman, ES; Papadopoulos, NE; Patel, S; Raymond, AK; Rodriguez, C; Worth, LL1
Enneking, WF; Lindner, NJ; Scarborough, MT; Spanier, SS1
Albiani, R; Bacci, G; Brach del Prever, A; Busca, A; Fagioli, F; Madon, E; Miniero, R; Nesi, F; Picci, P; Vassallo, E1
Bailey, CC; Gattamaneni, HR; Lashford, LS; Lewis, IJ; Michelagnoli, MP1
El-Deiry, WS; Enders, GH; Herlyn, M; Prabhu, NS; Satyamoorthy, K; Somasundaram, K; Tian, H1
An, T; Jia, SF; Kleinerman, ES; Worth, L1
Bauernhofer, T; Kasparek, AK; Kotz, R; Kuss, I; Pieber, TR; Ploner, F; Samonigg, H; Stöger, H1
de Montpreville, V; Munck, JN; Regnard, JF; Terrier, P; Ulusakarya, A1
Jia, SF; Kleinerman, ES; Worth, LL1
Bacci, G; Bertoni, F; Campanacci, M; Casadei, R; Fabbri, N; Ferrari, S; Forni, C; Longhi, A; Picci, P; Ruggieri, P; Versari, M1
Benetti, R; Brancolini, C; Del Sal, G; Monte, M; Paroni, G; Schneider, C1
Dong, YB; Elliott, MJ; McMasters, KM; Wong, SL; Yang, HL1
Boulares, AH; Contreras, FJ; Smulson, ME; Yakovlev, AG; Yoshihara, K; Zoltoski, AJ1
Bernstein, M; Devidas, M; Ferguson, W; Gebhardt, MC; Goorin, AM; Grier, HE; Harris, MB; Link, M; Schwartz, CL; Siegal, GP1
Hisada, T; Ito, T; Masuda, S; Mochida, A; Morinari, H; Nakahara, K; Nishi, K; Saito, K; Sasaki, S; Tahara, M; Yakumaru, K1
Aglietta, M; Bacci, G; Biasin, E; Brach del Prever, A; Fagioli, F; Ferrari, S; Madon, E; Palmero, A; Picci, P; Tienghi, A; Vassallo, E1
Daw, NC; Dome, JS; Kaste, SC; Meyer, WH; Pappo, AS; Pratt, CB; Rao, BN; Rodríguez-Galindo, C1
Black, T; Estrada-Aguilar, J; Greenberg, H; Hvizdala, E; Morse, S; Schroer, K; Walling, A1
Baba, H; Tomita, K; Tsuchiya, H; Ueda, Y; Yasutake, H; Yokogawa, A1
Flanigan, P; Freshney, RI; Hamilton, TG; Kaye, SB; Merry, S1
Avella, M; Bacci, G; Dallari, D; De Cristofaro, R; Ferruzzi, A; Manfrini, M; Marangolo, M; Mercuri, M; Picci, P; Pignatti, G1
Cassano, WF; Dickson, N; Graham-Pole, J1
Abbot, F; Cassano, W; Dickson, N; Graham-Pole, J; Heare, M; Heare, T; Kedar, A; Metha, P; Saleh, RA; Vander Griend, R1
Lampkin, BC; Wong, KY1

Reviews

9 review(s) available for etoposide and Osteosarcoma

ArticleYear
The role of chemotherapy for metastatic, relapsed and refractory osteosarcoma.
    Paediatric drugs, 2014, Volume: 16, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cyclophosphamide; Deoxycytidine; Docetaxel; Etoposide; Gemcitabine; Humans; Ifosfamide; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Taxoids

2014
An update on chemotherapy for osteosarcoma.
    Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:18

    Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Doxorubicin; Etoposide; Humans; Ifosfamide; Methotrexate; Neoadjuvant Therapy; Neoplasm Metastasis; Osteosarcoma; Prognosis; Randomized Controlled Trials as Topic

2015
Advanced therapeutic strategy for radiation-induced osteosarcoma in the skull base: a case report and review.
    Radiation oncology (London, England), 2012, Aug-10, Volume: 7

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Combined Modality Therapy; Etoposide; Female; Humans; Ifosfamide; Magnetic Resonance Imaging; Neoplasm Staging; Neoplasm, Residual; Neoplasms, Radiation-Induced; Osteosarcoma; Prognosis; Skull Base Neoplasms

2012
Combination of gemcitabine and irinotecan for recurrent metastatic osteogenic sarcoma.
    Clinical advances in hematology & oncology : H&O, 2005, Volume: 3, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Cisplatin; Combined Modality Therapy; Deoxycytidine; Doxorubicin; Etoposide; Femoral Neoplasms; Gemcitabine; Head and Neck Neoplasms; Humans; Ifosfamide; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Osteosarcoma; Palliative Care; Salvage Therapy; Scalp; Skin Neoplasms; Thoracotomy

2005
An update of Scandinavian studies of osteosarcoma.
    Cancer treatment and research, 1993, Volume: 62

    Topics: Adolescent; Adult; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Clinical Protocols; Combined Modality Therapy; Doxorubicin; Etoposide; Humans; Ifosfamide; Methotrexate; Osteosarcoma; Scandinavian and Nordic Countries; Survival Rate; Treatment Outcome

1993
Neoadjuvant chemotherapy for patients with osteosarcoma: University of Florida studies.
    Cancer treatment and research, 1993, Volume: 62

    Topics: Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Florida; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Life Tables; Lung Neoplasms; Methotrexate; Osteosarcoma; Survival Analysis; Treatment Outcome

1993
Combined treatment of metastatic osteosarcoma of the spine.
    Oncology, 1999, Volume: 57, Issue:4

    Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chemotherapy, Adjuvant; Doxorubicin; Etoposide; Femoral Neoplasms; Humans; Male; Neoadjuvant Therapy; Osteosarcoma; Spinal Neoplasms; Tomography, X-Ray Computed

1999
Extraskeletal osteosarcoma of the mediastinum after treatment of a mediastinal germ-cell tumor.
    American journal of clinical oncology, 1999, Volume: 22, Issue:6

    Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain Neoplasms; Cisplatin; Etoposide; Fatal Outcome; Follow-Up Studies; Germinoma; Humans; Male; Mediastinal Neoplasms; Neoplasm, Residual; Neoplasms, Second Primary; Osteosarcoma; Teratoma

1999
Indications for and benefits of intensive therapies in treatment of childhood cancers.
    Cancer, 1986, Jul-15, Volume: 58, Issue:2 Suppl

    Topics: Acute Disease; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Etoposide; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma; Melphalan; Methotrexate; Neoplasms; Osteosarcoma; Risk; Sarcoma, Ewing

1986

Trials

26 trial(s) available for etoposide and Osteosarcoma

ArticleYear
OLIE, ITCC-082: a Phase II trial of lenvatinib plus ifosfamide and etoposide in relapsed/refractory osteosarcoma.
    Future oncology (London, England), 2021, Volume: 17, Issue:32

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Etoposide; Humans; Ifosfamide; Middle Aged; Osteosarcoma; Phenylurea Compounds; Protein Kinase Inhibitors; Quality of Life; Quinolines; Young Adult

2021
Results of methotrexate-etoposide-ifosfamide based regimen (M-EI) in osteosarcoma patients included in the French OS2006/sarcome-09 study.
    European journal of cancer (Oxford, England : 1990), 2018, Volume: 88

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Diphosphonates; Doxorubicin; Etoposide; Female; France; Humans; Ifosfamide; Imidazoles; Kaplan-Meier Estimate; Male; Methotrexate; Neutropenia; Osteosarcoma; Young Adult; Zoledronic Acid

2018
Results of API-AI based regimen in osteosarcoma adult patients included in the French OS2006/Sarcome-09 study.
    International journal of cancer, 2020, 01-15, Volume: 146, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Etoposide; Feasibility Studies; Female; Follow-Up Studies; France; Humans; Ifosfamide; Kaplan-Meier Estimate; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Osteosarcoma; Prognosis; Survival Rate; Young Adult; Zoledronic Acid

2020
EURAMOS-1, an international randomised study for osteosarcoma: results from pre-randomisation treatment.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Combined Modality Therapy; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Interferon-alpha; Male; Methotrexate; Neoadjuvant Therapy; Osteosarcoma; Polyethylene Glycols; Quality of Life; Research Design; Young Adult

2015
Comparative outcome of Thai pediatric osteosarcoma treated with two protocols: the role of high-dose methotrexate (HDMTX) in a single institute experience.
    Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:22

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carboplatin; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Dose-Response Relationship, Drug; Etoposide; Extremities; Feasibility Studies; Female; Follow-Up Studies; Humans; Ifosfamide; Male; Maximum Tolerated Dose; Methotrexate; Neoadjuvant Therapy; Neoplasm Metastasis; Neoplasm Staging; Osteosarcoma; Prognosis; Retrospective Studies; Survival Rate

2014
Developing a prognostic model for patients with localized osteosarcoma treated with uniform chemotherapy protocol without high dose methotrexate: A single-center experience of 237 patients.
    Journal of surgical oncology, 2015, Volume: 112, Issue:6

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Ifosfamide; Male; Methotrexate; Neoadjuvant Therapy; Neoplasm Staging; Osteosarcoma; Prognosis; Retrospective Studies; Survival Rate

2015
Phase 2 trial of two courses of cyclophosphamide and etoposide for relapsed high-risk osteosarcoma patients.
    Cancer, 2009, Jul-01, Volume: 115, Issue:13

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cyclophosphamide; Disease-Free Survival; Etoposide; Female; Hematopoietic Stem Cell Mobilization; Humans; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Osteosarcoma

2009
[Treatment of relapsed osteosarcoma. Role of chemotherapy using ifosamide and carboplatin].
    Voprosy onkologii, 2010, Volume: 56, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carboplatin; Chemotherapy, Adjuvant; Doxorubicin; Etoposide; Female; Follow-Up Studies; Histiocytoma, Malignant Fibrous; Humans; Ifosfamide; Kaplan-Meier Estimate; Lung Neoplasms; Male; Neoplasm Recurrence, Local; Osteosarcoma; Treatment Outcome; Young Adult

2010
Clinical utility of biochemical bone turnover markers in children and adolescents with osteosarcoma.
    Advances in medical sciences, 2010, Volume: 55, Issue:2

    Topics: Adolescent; Adult; Alkaline Phosphatase; Antineoplastic Agents; Biomarkers; Child; Child, Preschool; Cisplatin; Collagen Type I; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Male; Methotrexate; Osteocalcin; Osteosarcoma; Young Adult

2010
Unstratified chemotherapy for non-metastatic osteosarcoma of the extremities in children.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2003, Volume: 102, Issue:6

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Cyclophosphamide; Epirubicin; Etoposide; Extremities; Female; Humans; Male; Methotrexate; Osteosarcoma; Statistics, Nonparametric; Survival Analysis; Taiwan; Treatment Outcome

2003
Glomerular dysfunction, independent of tubular dysfunction, induced by antineoplastic chemotherapy in children.
    Pediatrics international : official journal of the Japan Pediatric Society, 2004, Volume: 46, Issue:5

    Topics: Acute Disease; Adolescent; Albuminuria; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Creatinine; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Glomerular Filtration Rate; Humans; Kidney Tubules; Leukemia; Lymphoma; Methotrexate; Neoplasms; Neuroblastoma; Osteosarcoma; Proteinuria; Rhabdomyosarcoma; Vincristine

2004
A phase I/II study of doxorubicin, ifosfamide, etoposide and interval methotrexate in patients with poor prognosis osteosarcoma.
    Pediatric blood & cancer, 2006, Volume: 46, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Male; Osteosarcoma

2006
SFOP OS94: a randomised trial comparing preoperative high-dose methotrexate plus doxorubicin to high-dose methotrexate plus etoposide and ifosfamide in osteosarcoma patients.
    European journal of cancer (Oxford, England : 1990), 2007, Volume: 43, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Disease-Free Survival; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Ifosfamide; Male; Methotrexate; Osteosarcoma; Preoperative Care

2007
Continuous-infusion verapamil with etoposide in relapsed or resistant paediatric cancers.
    British journal of cancer, 1995, Volume: 71, Issue:4

    Topics: Adolescent; Adult; Bone Neoplasms; Child; Child, Preschool; Drug Administration Schedule; Drug Resistance, Multiple; Etoposide; Female; Hodgkin Disease; Humans; Infant; Infusions, Intravenous; Kidney Neoplasms; Male; Neoplasms; Neuroblastoma; Osteosarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Rhabdomyosarcoma; Sarcoma, Ewing; Verapamil; Wilms Tumor

1995
An update of Scandinavian studies of osteosarcoma.
    Cancer treatment and research, 1993, Volume: 62

    Topics: Adolescent; Adult; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Clinical Protocols; Combined Modality Therapy; Doxorubicin; Etoposide; Humans; Ifosfamide; Methotrexate; Osteosarcoma; Scandinavian and Nordic Countries; Survival Rate; Treatment Outcome

1993
Neoadjuvant chemotherapy for patients with osteosarcoma: University of Florida studies.
    Cancer treatment and research, 1993, Volume: 62

    Topics: Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Florida; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Life Tables; Lung Neoplasms; Methotrexate; Osteosarcoma; Survival Analysis; Treatment Outcome

1993
Acute myeloid leukemia in patients treated for rhabdomyosarcoma with cyclophosphamide and low-dose etoposide on Intergroup Rhabdomyosarcoma Study III: an interim report.
    Medical and pediatric oncology, 1994, Volume: 23, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Etoposide; Extremities; Family Health; Female; Humans; Infant; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Meningeal Neoplasms; Myelodysplastic Syndromes; Neoplasms, Second Primary; Odds Ratio; Osteosarcoma; Rhabdomyosarcoma; Rhabdomyosarcoma, Alveolar; Rhabdomyosarcoma, Embryonal; Risk Factors; Spinal Neoplasms

1994
Ifosfamide and etoposide in childhood osteosarcoma. A phase II study of the French Society of Paediatric Oncology.
    European journal of cancer (Oxford, England : 1990), 1997, Volume: 33, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Etoposide; Female; Humans; Ifosfamide; Male; Osteosarcoma; Survival Rate; Treatment Outcome

1997
Osteosarcoma of the extremities with synchronous lung metastases: long-term results in 44 patients treated with neoadjuvant chemotherapy.
    Journal of chemotherapy (Florence, Italy), 1998, Volume: 10, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carboplatin; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Disease-Free Survival; Epirubicin; Etoposide; Extremities; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Neoplasm Recurrence, Local; Osteosarcoma; Prognosis

1998
Phase II study of recombinant interleukin 1alpha and etoposide in patients with relapsed osteosarcoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:10

    Topics: Adolescent; Adult; Alopecia; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Bone Neoplasms; Capillary Leak Syndrome; Combined Modality Therapy; Cytokines; Drug Synergism; Etoposide; Feasibility Studies; Female; Femoral Neoplasms; Fever; Fibrosis; Gastrointestinal Diseases; Humans; Hypotension; Immunologic Factors; Interleukin-1; Lung Neoplasms; Male; Neutropenia; Osteosarcoma; Recombinant Proteins; Remission Induction; Respiration Disorders; Salvage Therapy; Treatment Outcome

1997
Local host response in osteosarcoma after chemotherapy referred to radiographs, CT, tumour necrosis and patient survival.
    Journal of cancer research and clinical oncology, 1998, Volume: 124, Issue:10

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Infant; Infant, Newborn; Male; Mesna; Methotrexate; Middle Aged; Necrosis; Neoadjuvant Therapy; Osteosarcoma; Predictive Value of Tests; Prognosis; Tomography, X-Ray Computed

1998
Feasibility of high-dose chemotherapy and autologous peripheral blood stem cell transplantation in children with high grade osteosarcoma.
    Bone marrow transplantation, 1998, Volume: 22 Suppl 5

    Topics: Adolescent; Antineoplastic Agents; Carboplatin; Child; Dose-Response Relationship, Drug; Etoposide; Feasibility Studies; Female; Hematopoietic Stem Cell Transplantation; Humans; Ifosfamide; Male; Osteosarcoma; Survival Rate; Transplantation, Autologous; Treatment Outcome

1998
Long-term outcome for patients with nonmetastatic osteosarcoma of the extremity treated at the istituto ortopedico rizzoli according to the istituto ortopedico rizzoli/osteosarcoma-2 protocol: an updated report.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Dec-15, Volume: 18, Issue:24

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Disease-Free Survival; Doxorubicin; Etoposide; Extremities; Female; Fertility; Follow-Up Studies; Humans; Ifosfamide; Male; Methotrexate; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Osteosarcoma; Patient Compliance; Plastic Surgery Procedures; Postoperative Complications; Radiography; Reoperation; Survival Rate

2000
Phase II/III trial of etoposide and high-dose ifosfamide in newly diagnosed metastatic osteosarcoma: a pediatric oncology group trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Jan-15, Volume: 20, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Disease-Free Survival; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Ifosfamide; Infusions, Intravenous; Male; Neoplasm Metastasis; Neutropenia; Osteosarcoma; Thrombocytopenia; Treatment Outcome

2002
High-dose chemotherapy in the treatment of relapsed osteosarcoma: an Italian sarcoma group study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Apr-15, Volume: 20, Issue:8

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carboplatin; Child; Cyclophosphamide; Etoposide; Feasibility Studies; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Male; Neoplasm Recurrence, Local; Osteosarcoma; Remission Induction; Survival Analysis; Transplantation, Autologous

2002
Effect of chemotherapy combined with caffeine for osteosarcoma.
    Journal of cancer research and clinical oncology, 1992, Volume: 118, Issue:8

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Caffeine; Calcaneus; Chemotherapy, Adjuvant; Child; Cisplatin; Combined Modality Therapy; Doxorubicin; Etoposide; Female; Femoral Neoplasms; Humans; Ifosfamide; Infusions, Intra-Arterial; Male; Methotrexate; Osteosarcoma; Salvage Therapy; Tibia

1992

Other Studies

85 other study(ies) available for etoposide and Osteosarcoma

ArticleYear
Intensive Multimodal Therapy Combined With Long-term Temozolomide and Etoposide Treatment for Recurrent Osteosarcoma to the Liver and Stomach.
    Journal of pediatric hematology/oncology, 2022, 05-01, Volume: 44, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Combined Modality Therapy; Etoposide; Humans; Liver; Neoplasm Recurrence, Local; Osteosarcoma; Stomach; Temozolomide

2022
Deficiency of TRDMT1 impairs exogenous RNA-based response and promotes retrotransposon activity during long-term culture of osteosarcoma cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2022, Volume: 80

    Topics: Antineoplastic Agents, Phytogenic; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA (Cytosine-5-)-Methyltransferases; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Osteosarcoma; Retroelements; RNA

2022
Temozolomide and etoposide combination for the treatment of relapsed osteosarcoma.
    Japanese journal of clinical oncology, 2020, Aug-04, Volume: 50, Issue:8

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Etoposide; Female; Humans; Male; Neoplasm Recurrence, Local; Osteosarcoma; Prognosis; Retrospective Studies; Temozolomide; Young Adult

2020
Efficacy and safety of oral metronomic etoposide in adult patients with metastatic osteosarcoma.
    Cancer medicine, 2021, Volume: 10, Issue:1

    Topics: Administration, Metronomic; Administration, Oral; Adult; Aged; Antineoplastic Agents, Phytogenic; Bone Neoplasms; Disease Progression; Etoposide; Female; Humans; Male; Middle Aged; Osteosarcoma; Progression-Free Survival; Retrospective Studies; Time Factors; Young Adult

2021
Temporal modulation of the NF-κB RelA network in response to different types of DNA damage.
    The Biochemical journal, 2021, 02-12, Volume: 478, Issue:3

    Topics: Amino Acid Motifs; Amino Acid Sequence; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Chromatography, Liquid; Consensus Sequence; DNA Breaks, Double-Stranded; DNA Damage; DNA Replication; DNA, Neoplasm; Etoposide; Humans; Hydroxyurea; Osteosarcoma; Phosphorylation; Protein Interaction Maps; Protein Kinases; Protein Processing, Post-Translational; Proteomics; Tandem Mass Spectrometry; Time Factors; Transcription Factor RelA

2021
Oral etoposide as a single agent in childhood and young adult cancer in England: Still a poorly evaluated palliative treatment.
    Pediatric blood & cancer, 2021, Volume: 68, Issue:11

    Topics: Administration, Oral; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Etoposide; Humans; Neoplasms, Germ Cell and Embryonal; Osteosarcoma; Palliative Care; Young Adult

2021
Mdm2 selectively suppresses DNA damage arising from inhibition of topoisomerase II independent of p53.
    Oncogene, 2017, 11-02, Volume: 36, Issue:44

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; DNA Breaks, Double-Stranded; DNA Damage; DNA Topoisomerases, Type II; Doxorubicin; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Knockout; Osteosarcoma; Proto-Oncogene Proteins c-mdm2; Topoisomerase II Inhibitors; Tumor Suppressor Protein p53

2017
Polymer-lipid hybrid nanoparticles-based paclitaxel and etoposide combinations for the synergistic anticancer efficacy in osteosarcoma.
    Colloids and surfaces. B, Biointerfaces, 2017, Nov-01, Volume: 159

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Delivery Systems; Etoposide; Humans; Nanoparticles; Osteosarcoma; Paclitaxel; Polymers

2017
Anti-tumour efficacy of etoposide alone and in combination with piroxicam against canine osteosarcoma in a xenograft model.
    Research in veterinary science, 2017, Volume: 113

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Dog Diseases; Dogs; Etoposide; Heterografts; Mice; Mice, Inbred BALB C; Osteosarcoma; Piroxicam

2017
Combination of etoposide and fisetin results in anti-cancer efficiency against osteosarcoma cell models.
    Archives of toxicology, 2018, Volume: 92, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin B1; Cyclin E; Etoposide; Flavonoids; Flavonols; Gene Expression Regulation, Neoplastic; Humans; Oncogene Proteins; Osteosarcoma; Tumor Stem Cell Assay

2018
Endostar combined with chemotherapy in a pediatric osteosarcoma with pulmonary metastasis and malignant pleural effusion: A case report.
    Medicine, 2017, Volume: 96, Issue:51

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Endostatins; Etoposide; Humans; Ifosfamide; Lung Neoplasms; Osteosarcoma; Pleural Effusion, Malignant; Recombinant Proteins

2017
Anti-neoplastic effects of topoisomerase inhibitors in canine mammary carcinoma, melanoma, and osteosarcoma cell lines.
    The Japanese journal of veterinary research, 2017, Volume: 65, Issue:1

    Topics: Animals; Antineoplastic Agents; Carcinoma; Cell Line, Tumor; Dog Diseases; Dogs; Etoposide; Female; Mammary Neoplasms, Animal; Melanoma; Mice; Neoplasms, Experimental; Osteosarcoma; Topoisomerase Inhibitors

2017
Etoposide phosphate for pediatric orthopedic malignancies after intravenous etoposide hypersensitivity.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2020, Volume: 26, Issue:1

    Topics: Adolescent; Bone Neoplasms; Drug Hypersensitivity; Etoposide; Humans; Male; Organophosphorus Compounds; Osteosarcoma; Sarcoma, Ewing

2020
ABCG1 and Pgp identify drug resistant, self-renewing osteosarcoma cells.
    Cancer letters, 2019, 07-01, Volume: 453

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; Bone Neoplasms; Cell Growth Processes; Cell Line, Tumor; Dactinomycin; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; HEK293 Cells; Hep G2 Cells; Humans; MCF-7 Cells; Neoplastic Stem Cells; Osteosarcoma; RNA, Messenger; Vincristine

2019
Clinical Prognostic Factors and Outcome in Pediatric Osteosarcoma: Effect of Delay in Local Control and Degree of Necrosis in a Multidisciplinary Setting in Lebanon.
    Journal of global oncology, 2019, Volume: 5

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Disease-Free Survival; Doxorubicin; Etoposide; Female; Humans; Infant; Lebanon; Male; Methotrexate; Neoadjuvant Therapy; Neoplasm Metastasis; Osteosarcoma; Prognosis; Retrospective Studies; Risk Assessment; Treatment Outcome

2019
Osteosarcoma journey over two decades in India: Small steps, big changes.
    Pediatric blood & cancer, 2019, Volume: 66, Issue:9

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Disease-Free Survival; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; India; Male; Middle Aged; Osteosarcoma; Survival Rate

2019
YM155 enhances the cytotoxic activity of etoposide against canine osteosarcoma cells.
    The Journal of veterinary medical science, 2019, Aug-24, Volume: 81, Issue:8

    Topics: Animals; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Cell Proliferation; Dog Diseases; Dogs; Drug Synergism; Etoposide; Humans; Imidazoles; Mice; Naphthoquinones; Osteosarcoma; Survivin; Xenograft Model Antitumor Assays

2019
Induction of apoptosis through caspase-independent or caspase-9-dependent pathway in mouse and human osteosarcoma cells by a new nitroxyl spin-labeled derivative of podophyllotoxin.
    Apoptosis : an international journal on programmed cell death, 2013, Volume: 18, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 9; Caspase Inhibitors; Caspases; Cell Cycle; Cell Line, Tumor; Cell Proliferation; DNA Fragmentation; Drug Therapy, Combination; Endodeoxyribonucleases; Etoposide; Humans; Mice; Osteosarcoma; Podophyllotoxin; Spin Labels

2013
Metastasis of osteosarcoma to stomach made clinically evident by hematemesis: a case report.
    World journal of surgical oncology, 2013, Feb-26, Volume: 11

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carboplatin; Cisplatin; Combined Modality Therapy; Doxorubicin; Etoposide; Gastrectomy; Hematemesis; Humans; Ifosfamide; Male; Neoplasm Staging; Osteosarcoma; Prognosis; Stomach Neoplasms

2013
Extraskeletal Osteosarcoma: An International Rare Cancer Network Study.
    American journal of clinical oncology, 2016, Volume: 39, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Chemotherapy, Adjuvant; Cisplatin; Cohort Studies; Deoxycytidine; Disease-Free Survival; Doxorubicin; Etoposide; Female; Gemcitabine; Humans; Ifosfamide; Lower Extremity; Male; Methotrexate; Middle Aged; Mitomycin; Multivariate Analysis; Neoadjuvant Therapy; Neoplasm Grading; Neoplasm Staging; Osteosarcoma; Pelvic Neoplasms; Prognosis; Radiotherapy; Rare Diseases; Retroperitoneal Neoplasms; Retrospective Studies; Soft Tissue Neoplasms; Tumor Burden; Young Adult

2016
Reticulated hyperpigmentation following chemotherapy for radiation-induced osteosarcoma.
    Journal of the American Academy of Dermatology, 2014, Volume: 71, Issue:1

    Topics: Anti-Inflammatory Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Eruptions; Etoposide; Humans; Hyperpigmentation; Ifosfamide; Male; Methotrexate; Middle Aged; Neoplasms, Radiation-Induced; Orbital Neoplasms; Osteosarcoma; Triamcinolone

2014
Osteopontin upregulates the expression of glucose transporters in osteosarcoma cells.
    PloS one, 2014, Volume: 9, Issue:10

    Topics: Antineoplastic Agents; Bone Neoplasms; Cell Line, Tumor; Daunorubicin; Etoposide; Fluorouracil; Glucose Transport Proteins, Facilitative; Glucose Transporter Type 1; Glucose Transporter Type 3; Humans; Integrin alphaVbeta3; Membrane Transport Modulators; Methotrexate; Osteopontin; Osteosarcoma; Phloretin; Up-Regulation

2014
p53-dependent activation of microRNA-34a in response to etoposide-induced DNA damage in osteosarcoma cell lines not impaired by dominant negative p53 expression.
    PloS one, 2014, Volume: 9, Issue:12

    Topics: Antineoplastic Agents; Apoptosis; Base Sequence; Blotting, Western; Bone Neoplasms; Cell Cycle; Cell Proliferation; Chromatin Immunoprecipitation; DNA Damage; DNA Methylation; Etoposide; Gene Expression Regulation, Neoplastic; Genes, Dominant; Humans; MicroRNAs; Molecular Sequence Data; Mutation; Osteosarcoma; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Nucleic Acid; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2014
Paclitaxel and etoposide co-loaded polymeric nanoparticles for the effective combination therapy against human osteosarcoma.
    Journal of nanobiotechnology, 2015, Mar-21, Volume: 13

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bone Neoplasms; Cell Cycle; Cell Line, Tumor; Drug Carriers; Etoposide; Humans; Lactic Acid; Nanoparticles; Osteosarcoma; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer

2015
High-dose chemotherapy and autologous stem cell transplantation with melphalan, etoposide and carboplatin for high-risk osteosarcoma.
    Bone marrow transplantation, 2015, Volume: 50, Issue:10

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Melphalan; Osteosarcoma; Transplantation Conditioning; Transplantation, Autologous; Young Adult

2015
Targeting DNA-PKcs increased anticancer drug sensitivity by suppressing DNA damage repair in osteosarcoma cell line MG63.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2015, Volume: 36, Issue:12

    Topics: Cell Line, Tumor; Cisplatin; DNA Breaks, Double-Stranded; DNA Damage; DNA Repair; DNA-Activated Protein Kinase; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Recurrence, Local; Nuclear Proteins; Osteosarcoma

2015
YU238259 Is a Novel Inhibitor of Homology-Dependent DNA Repair That Exhibits Synthetic Lethality and Radiosensitization in Repair-Deficient Tumors.
    Molecular cancer research : MCR, 2015, Volume: 13, Issue:10

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Bone Neoplasms; Cell Line, Tumor; Circular Dichroism; Colorectal Neoplasms; DNA Breaks, Double-Stranded; DNA Repair; Drug Synergism; Etoposide; Glioma; High-Throughput Screening Assays; Humans; Intercalating Agents; Mice; Mice, Nude; Molecular Structure; Neoplasms; Osteosarcoma; Poly(ADP-ribose) Polymerase Inhibitors; Radiation-Sensitizing Agents; Small Molecule Libraries; Sulfonamides; Xenograft Model Antitumor Assays

2015
Highly effective reduced toxicity dose-intensive pilot protocol for non-metastatic limb osteogenic sarcoma (SCOS 89).
    Cancer chemotherapy and pharmacology, 2015, Volume: 76, Issue:5

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Doxorubicin; Drug Substitution; Etoposide; Female; Follow-Up Studies; Hearing Loss; Humans; Ifosfamide; Kidney Diseases; Leucovorin; Male; Methotrexate; Osteosarcoma; Pilot Projects; Stroke Volume; Survival Rate; Treatment Outcome; Young Adult

2015
Intensified Chemotherapy With Dexrazoxane Cardioprotection in Newly Diagnosed Nonmetastatic Osteosarcoma: A Report From the Children's Oncology Group.
    Pediatric blood & cancer, 2016, Volume: 63, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cardiotonic Agents; Child; Child, Preschool; Cisplatin; Dexrazoxane; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Infant; Infant, Newborn; Male; Methotrexate; Osteosarcoma; Treatment Outcome; Ventricular Dysfunction

2016
Ewing Sarcoma of the Bone With EWS/FLI1 Translocation After Successful Treatment of Primary Osteosarcoma.
    Journal of pediatric hematology/oncology, 2017, Volume: 39, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Femoral Neoplasms; Humans; Ifosfamide; Limb Salvage; Methotrexate; Neoplasms, Second Primary; Oncogene Proteins, Fusion; Osteosarcoma; Proto-Oncogene Protein c-fli-1; Remission Induction; RNA-Binding Protein EWS; Sarcoma, Ewing; Vincristine

2017
Effects of etoposide alone and in combination with piroxicam on canine osteosarcoma cell lines.
    Veterinary journal (London, England : 1997), 2016, Volume: 218

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Apoptosis; Bone Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dog Diseases; Dogs; Down-Regulation; Etoposide; Osteosarcoma; Piroxicam; Up-Regulation

2016
ViscumTT induces apoptosis and alters IAP expression in osteosarcoma in vitro and has synergistic action when combined with different chemotherapeutic drugs.
    BMC complementary and alternative medicine, 2017, Jan-07, Volume: 17, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Child; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Etoposide; Humans; Inhibitor of Apoptosis Proteins; Male; Osteosarcoma; Plant Extracts; Survivin; Triterpenes; Tumor Cells, Cultured; Viscum album; X-Linked Inhibitor of Apoptosis Protein

2017
Hesperetin-etoposide combinations induce cytotoxicity in U2OS cells: Implications on therapeutic developments for osteosarcoma.
    DNA repair, 2017, Volume: 50

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cytotoxins; Doxorubicin; Etoposide; Hesperidin; Humans; Osteosarcoma

2017
COX-2 expression correlates with survival in patients with osteosarcoma lung metastases.
    Journal of pediatric hematology/oncology, 2008, Volume: 30, Issue:7

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Biomarkers, Tumor; Bone Neoplasms; Child; Cisplatin; Combined Modality Therapy; Cyclooxygenase 2; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Proteins; Neoplasm Recurrence, Local; Osteosarcoma; Pneumonectomy; Prognosis; Retrospective Studies; Salvage Therapy; Survival Analysis

2008
WRN protects against topo I but not topo II inhibitors by preventing DNA break formation.
    DNA repair, 2008, Dec-01, Volume: 7, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Bone Neoplasms; Bromodeoxyuridine; Cell Cycle; Cell Survival; Colony-Forming Units Assay; DNA Breaks; DNA Repair; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Enzyme Inhibitors; Etoposide; Exodeoxyribonucleases; Histones; Humans; Osteosarcoma; RecQ Helicases; RNA, Small Interfering; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Topotecan; Tumor Cells, Cultured; Werner Syndrome Helicase

2008
Caffeine-potentiated chemotherapy for metastatic osteosarcoma.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2009, Volume: 14, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Caffeine; Child; Cisplatin; Doxorubicin; Etoposide; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Osteosarcoma; Young Adult

2009
Moyamoya in a child treated with interferon for recurrent osteosarcoma.
    Journal of pediatric hematology/oncology, 2010, Volume: 32, Issue:6

    Topics: Antineoplastic Agents; Bone Neoplasms; Carotid Artery Diseases; Cerebral Arterial Diseases; Cerebral Infarction; Chemotherapy, Adjuvant; Child; Cisplatin; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Interferon-alpha; Lung Neoplasms; Magnetic Resonance Angiography; Methotrexate; Moyamoya Disease; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Osteosarcoma; Thyroiditis, Autoimmune

2010
Sensitization of osteosarcoma cell line SaOS-2 to chemotherapy by downregulating survivin.
    Archives of medical research, 2010, Volume: 41, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Base Sequence; Bone Neoplasms; Caspase 3; Cell Line, Tumor; Cell Survival; Cisplatin; Combined Modality Therapy; Down-Regulation; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Genetic Therapy; Humans; Inhibitor of Apoptosis Proteins; Membrane Potential, Mitochondrial; Microtubule-Associated Proteins; Osteosarcoma; RNA, Small Interfering; Survivin

2010
Down-regulation of XIAP by AEG35156 in paediatric tumour cells induces apoptosis and sensitises cells to cytotoxic agents.
    Oncology reports, 2011, Volume: 25, Issue:4

    Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Bone Neoplasms; Child; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Humans; Oligonucleotides; Osteosarcoma; Rhabdomyosarcoma; Sarcoma, Ewing; Tumor Cells, Cultured; Tumor Stem Cell Assay; Vincristine; X-Linked Inhibitor of Apoptosis Protein

2011
Metastatic osteosarcoma presenting as a single pulmonary microembolus.
    Journal of pediatric surgery, 2011, Volume: 46, Issue:3

    Topics: Adolescent; Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Diagnosis, Differential; Diagnostic Errors; Enoxaparin; Etoposide; Femoral Neoplasms; Humans; Ifosfamide; Limb Salvage; Male; Neoplastic Cells, Circulating; Osteosarcoma; Pneumonectomy; Postoperative Complications; Pulmonary Artery; Pulmonary Embolism; Thromboembolism; Tomography, X-Ray Computed

2011
[Organ-preserving interventions in combined therapy of children and adolescents with osteosarcoma].
    Voprosy onkologii, 2012, Volume: 58, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Bone Transplantation; Chemotherapy, Cancer, Regional Perfusion; Child; Cisplatin; Cohort Studies; Disease-Free Survival; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Methotrexate; Neoadjuvant Therapy; Orthopedic Procedures; Osteosarcoma; Transplantation, Autologous; Treatment Outcome

2012
Synergistic increase in the sensitivity of osteosarcoma cells to thermochemotherapy with combination of paclitaxel and etoposide.
    Molecular medicine reports, 2012, Volume: 6, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; Bone Neoplasms; Cell Line, Tumor; Cell Survival; Drug Therapy, Combination; Etoposide; fas Receptor; Humans; Osteosarcoma; Paclitaxel; Temperature

2012
Perifosine induces cell apoptosis in human osteosarcoma cells: new implication for osteosarcoma therapy?
    Cell biochemistry and biophysics, 2013, Volume: 65, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Etoposide; Humans; JNK Mitogen-Activated Protein Kinases; Mechanistic Target of Rapamycin Complex 1; Multiprotein Complexes; Osteosarcoma; Phosphorylcholine; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53

2013
Gene expression levels of human shelterin complex and shelterin-associated factors regulated by the topoisomerase II inhibitors doxorubicin and etoposide in human cultured cells.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2013, Volume: 34, Issue:2

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Blotting, Western; Bone Neoplasms; Caspases; Cells, Cultured; Doxorubicin; Etoposide; Fibroblasts; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Luciferases; Osteosarcoma; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Shelterin Complex; Telomere-Binding Proteins; Telomeric Repeat Binding Protein 1; Topoisomerase II Inhibitors

2013
The Poly(ADP-ribose) polymerase-1-regulated endonuclease DNAS1L3 is required for etoposide-induced internucleosomal DNA fragmentation and increases etoposide cytotoxicity in transfected osteosarcoma cells.
    Cancer research, 2002, Aug-01, Volume: 62, Issue:15

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis Regulatory Proteins; Bone Neoplasms; Calcium; Caspase 3; Caspases; DNA Fragmentation; Endodeoxyribonucleases; Enzyme Activation; Etoposide; Humans; Nucleosomes; Osteosarcoma; Poly(ADP-ribose) Polymerases; Proteins; Recombinant Proteins; Staurosporine; Transfection; Tumor Cells, Cultured

2002
Fertility in male patients treated with neoadjuvant chemotherapy for osteosarcoma.
    Journal of pediatric hematology/oncology, 2003, Volume: 25, Issue:4

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Follow-Up Studies; Humans; Ifosfamide; Incidence; Infant, Newborn; Italy; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Oligospermia; Osteosarcoma; Puberty; Semen Preservation; Sperm Count; Surveys and Questionnaires

2003
E1A oncogene-induced sensitization of human tumor cells to innate immune defenses and chemotherapy-induced apoptosis in vitro and in vivo.
    Cancer research, 2003, Jun-15, Volume: 63, Issue:12

    Topics: Adenovirus E1A Proteins; Adenoviruses, Human; Animals; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Line; Cytotoxicity, Immunologic; Drug Resistance, Neoplasm; Etoposide; Female; Fibrosarcoma; Genes, p53; Humans; Immunologic Surveillance; Kidney; Killer Cells, Natural; Mice; Mice, Nude; Oncogenes; Osteosarcoma; Rats; Rats, Nude; Time Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2003
Induction of cell death of human osteogenic sarcoma cells by zoledronic acid resembles anoikis.
    Bone, 2003, Volume: 33, Issue:2

    Topics: Anoikis; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Bone Neoplasms; Caspases; Cell Adhesion; Cell Division; Cell Line, Tumor; Cholesterol; Diphosphonates; DNA Fragmentation; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Humans; Imidazoles; Osteosarcoma; Zoledronic Acid

2003
Selective and nonselective toxicity of TRAIL/Apo2L combined with chemotherapy in human bone tumour cells vs. normal human cells.
    International journal of cancer, 2003, Dec-20, Volume: 107, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Bone Marrow Cells; Bone Marrow Neoplasms; Cell Survival; Cisplatin; Combined Modality Therapy; Doxorubicin; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Membrane Glycoproteins; Osteosarcoma; Reverse Transcriptase Polymerase Chain Reaction; Sarcoma, Ewing; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2003
[p33(ING1b) enhances chemosensitivity of osteosarcoma cell U2OS to etoposide].
    Ai zheng = Aizheng = Chinese journal of cancer, 2004, Volume: 23, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Bone Neoplasms; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; DNA-Binding Proteins; Drug Synergism; Etoposide; Genes, Tumor Suppressor; Humans; Inhibitor of Growth Protein 1; Intracellular Signaling Peptides and Proteins; Nuclear Proteins; Osteosarcoma; Proteins; Transfection; Tumor Suppressor Proteins

2004
[Neoadjuvant chemotherapy for osteosarcoma].
    Zhonghua yi xue za zhi, 2004, Jul-17, Volume: 84, Issue:14

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Drug Administration Schedule; Etoposide; Female; Femoral Neoplasms; Humans; Ifosfamide; Male; Neoadjuvant Therapy; Osteosarcoma; Retrospective Studies

2004
Tumor excision and reconstruction of the upper cervical spine: a multidisciplinary approach.
    Plastic and reconstructive surgery, 2004, Volume: 114, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Axis, Cervical Vertebra; Bone Transplantation; Cervical Atlas; Chemotherapy, Adjuvant; Chondrosarcoma; Chordoma; Combined Modality Therapy; Cranial Fossa, Posterior; Etoposide; Fatal Outcome; Female; Femoral Neoplasms; Humans; Ifosfamide; Interdisciplinary Communication; Internal Fixators; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Osteosarcoma; Palliative Care; Patient Care Team; Proton Therapy; Remission Induction; Skull Base Neoplasms; Spinal Fusion; Spinal Neoplasms; Surgical Flaps

2004
Differential impact of diverse anticancer chemotherapeutics on the Cdc25A-degradation checkpoint pathway.
    Experimental cell research, 2005, Jan-15, Volume: 302, Issue:2

    Topics: Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antineoplastic Agents, Phytogenic; Camptothecin; cdc25 Phosphatases; Cell Cycle; Cell Line, Transformed; Cell Line, Tumor; Checkpoint Kinase 1; Checkpoint Kinase 2; Cisplatin; Cyclin E; DNA; DNA Damage; Doxorubicin; Enzyme Activation; Etoposide; Flow Cytometry; Humans; Kinetics; Osteosarcoma; Paclitaxel; Protein Kinases; Protein Serine-Threonine Kinases; Radiation, Ionizing; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Ultraviolet Rays

2005
Long-term survival in high-grade axial osteosarcoma with bone and lung metastases treated with chemotherapy only.
    Journal of pediatric hematology/oncology, 2005, Volume: 27, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carboplatin; Child, Preschool; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Ifosfamide; Lumbar Vertebrae; Lung Neoplasms; Male; Methotrexate; Osteosarcoma; Thoracic Vertebrae; Time Factors; Tomography, X-Ray Computed

2005
Acquisition of anoikis resistance in human osteosarcoma cells does not alter sensitivity to chemotherapeutic agents.
    BMC cancer, 2005, Apr-13, Volume: 5

    Topics: Anoikis; Antineoplastic Agents; Apoptosis; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Separation; Cell Survival; Cisplatin; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Extracellular Matrix; Flow Cytometry; Humans; Hypoxia; Neoplasm Metastasis; Osteosarcoma; Paclitaxel; Propidium; Vinblastine

2005
Transfection of Smac sensitizes tumor cells to etoposide-induced apoptosis and eradicates established human hepatoma in vivo.
    Cancer gene therapy, 2006, Volume: 13, Issue:4

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Bone Neoplasms; Carcinoma, Hepatocellular; Cell Line, Tumor; Combined Modality Therapy; Etoposide; Female; Fluorouracil; Genetic Therapy; Humans; Intracellular Signaling Peptides and Proteins; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondrial Proteins; Osteosarcoma; Proto-Oncogene Proteins c-bcl-2; Transfection; Tumor Suppressor Protein p53

2006
The p33ING1b tumor suppressor cooperates with p53 to induce apoptosis in response to etoposide in human osteosarcoma cells.
    Life sciences, 2006, Feb-23, Volume: 78, Issue:13

    Topics: Apoptosis; Bone Neoplasms; Cell Division; Cell Line, Tumor; Etoposide; Humans; Inhibitor of Growth Protein 1; Intracellular Signaling Peptides and Proteins; Nuclear Proteins; Osteosarcoma; Transfection; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

2006
Early G2/M checkpoint failure as a molecular mechanism underlying etoposide-induced chromosomal aberrations.
    The Journal of clinical investigation, 2006, Volume: 116, Issue:1

    Topics: Bone Neoplasms; Cell Cycle; Cell Division; Cell Line; Cell Line, Tumor; Chromosome Aberrations; Chromosome Banding; Chromosomes, Human, Pair 11; Cloning, Molecular; Etoposide; G2 Phase; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Humans; Myeloid-Lymphoid Leukemia Protein; Osteosarcoma; Translocation, Genetic

2006
Lysocellin, a metabolite of the novel drug 'alopestatin', induces G1 arrest and prevents cytotoxicity induced by etoposide.
    International journal of oncology, 2006, Volume: 28, Issue:4

    Topics: Alopecia; Animals; Animals, Newborn; Antineoplastic Agents, Phytogenic; Area Under Curve; Blotting, Northern; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Down-Regulation; Etoposide; Female; Furans; G1 Phase; Gene Expression; Humans; Male; Osteosarcoma; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Up-Regulation

2006
[Preliminary report of combination chemotherapy including Arsenic trioxide for stage III osteosarcoma and Ewing sarcoma].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 2006, Jun-15, Volume: 44, Issue:12

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Bone Neoplasms; Child; Etoposide; Female; Follow-Up Studies; Humans; Male; Osteosarcoma; Oxides; Paclitaxel; Sarcoma, Ewing; Treatment Outcome

2006
Expression levels and activation of a PXR variant are directly related to drug resistance in osteosarcoma cell lines.
    Cancer, 2007, Mar-01, Volume: 109, Issue:5

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Line, Tumor; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Humans; Osteosarcoma; Pregnane X Receptor; Protein Isoforms; Receptors, Steroid; Reverse Transcriptase Polymerase Chain Reaction; Rifampin; RNA, Messenger; RNA, Small Interfering

2007
Expression of androgen receptor is negatively regulated by p53.
    Neoplasia (New York, N.Y.), 2007, Volume: 9, Issue:12

    Topics: 5' Untranslated Regions; Adenocarcinoma; Androgens; Bone Neoplasms; Cell Line, Tumor; Colorectal Neoplasms; Consensus Sequence; DNA, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; Male; Neoplasms, Hormone-Dependent; Osteosarcoma; Promoter Regions, Genetic; Prostatic Neoplasms; Receptors, Androgen; RNA, Small Interfering; Transfection; Tumor Suppressor Protein p53

2007
Interferonalpha enhances etoposide-induced apoptosis in human osteosarcoma U2OS cells by a p53-dependent pathway.
    Life sciences, 2008, Feb-13, Volume: 82, Issue:7-8

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Bone Neoplasms; Cell Line, Tumor; Cell Survival; Drug Combinations; Etoposide; Humans; Interferon-alpha; Mutation; Osteosarcoma; Proto-Oncogene Proteins c-mdm2; Tumor Suppressor Protein p53

2008
Multimodality treatment of osteosarcoma: radiation in a high-risk cohort.
    Pediatric blood & cancer, 2008, Volume: 50, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Cohort Studies; Combined Modality Therapy; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Ifosfamide; Male; Medical Records; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Radiotherapy Dosage; Retrospective Studies; Risk Factors; Survival Rate

2008
Interdisciplinary combined treatment of craniofacial osteosarcoma with neoadjuvant and adjuvant chemotherapy and excision of the tumour: a retrospective study.
    The British journal of oral & maxillofacial surgery, 2008, Volume: 46, Issue:7

    Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Ifosfamide; Male; Mandibular Neoplasms; Maxillary Neoplasms; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Osteosarcoma; Radiotherapy, Adjuvant; Retrospective Studies; Survival Rate; Young Adult

2008
Lack of functional retinoblastoma protein mediates increased resistance to antimetabolites in human sarcoma cell lines.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Oct-24, Volume: 92, Issue:22

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Base Sequence; Bone Neoplasms; Cell Division; Cell Line; Cisplatin; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Fibrosarcoma; Floxuridine; Humans; Liposarcoma; Methotrexate; Molecular Sequence Data; Oligonucleotide Probes; Osteosarcoma; Recombinant Proteins; Retinoblastoma Protein; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Transfection; Tumor Cells, Cultured

1995
Osteosarcoma following radiation treatment for meningioma: report of a case and effective treatment with chemotherapy.
    Journal of neuro-oncology, 1994, Volume: 21, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carboplatin; Cisplatin; Dactinomycin; Etoposide; Female; Gonadotropin-Releasing Hormone; Humans; Ifosfamide; Lung Neoplasms; Meningeal Neoplasms; Meningioma; Methotrexate; Neoplasms, Radiation-Induced; Neoplasms, Second Primary; Osteosarcoma; Tamoxifen; Tomography, X-Ray Computed; Vincristine

1994
Serum methotrexate (MTX) concentrations and prognosis in patients with osteosarcoma of the extremities treated with a multidrug neoadjuvant regimen.
    Journal of chemotherapy (Florence, Italy), 1993, Volume: 5, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Child; Cisplatin; Doxorubicin; Drug Administration Schedule; Etoposide; Extremities; Female; Humans; Ifosfamide; Male; Methotrexate; Osteosarcoma; Prognosis

1993
Intense gallbladder uptake associated with chemotherapy. An unusual finding in pediatric skeletal scintigraphy.
    Clinical nuclear medicine, 1995, Volume: 20, Issue:11

    Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone and Bones; Bone Neoplasms; Child; Etoposide; Female; Gallbladder; Humans; Ifosfamide; Liver; Male; Osteosarcoma; Radionuclide Imaging; Sarcoma, Ewing; Technetium Tc 99m Medronate; Tissue Distribution

1995
[Pilot study of relapsed osteosarcoma and brain tumor with ifosfamide, carboplatin and etoposide (ICE therapy)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1998, Volume: 25, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brain Neoplasms; Carboplatin; Child; Drug Administration Schedule; Etoposide; Female; Fever; Humans; Ifosfamide; Lung Neoplasms; Male; Neoplasm Recurrence, Local; Neutropenia; Osteosarcoma; Pilot Projects; Thrombocytopenia

1998
Postsurgical etoposide-ifosfamide regimen in poor-risk nonmetastatic osteogenic sarcoma.
    American journal of clinical oncology, 1998, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Disease-Free Survival; Etoposide; Female; Humans; Ifosfamide; Male; Osteosarcoma; Prospective Studies; Remission Induction; Salvage Therapy

1998
Ifosfamide/etoposide alternating with high-dose methotrexate: evaluation of a chemotherapy regimen for poor-risk osteosarcoma.
    British journal of cancer, 1999, Volume: 79, Issue:7-8

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Drug Administration Schedule; Etoposide; Feasibility Studies; Female; Humans; Ifosfamide; Male; Methotrexate; Osteosarcoma; Recurrence; Retrospective Studies

1999
The administration schedule of cyclin-dependent kinase inhibitor gene therapy and etoposide chemotherapy is a major determinant of cytotoxicity.
    International journal of oncology, 1999, Volume: 15, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Bone Neoplasms; Cell Cycle; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; DNA Damage; Drug Administration Schedule; Enzyme Inhibitors; Etoposide; Genes, p16; Genetic Therapy; Humans; Osteosarcoma; Topoisomerase II Inhibitors

1999
Interferon-alpha enhances the sensitivity of human osteosarcoma cells to etoposide.
    Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 1999, Volume: 19, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; DNA Topoisomerases, Type II; Drug Resistance, Neoplasm; Drug Synergism; Etoposide; Humans; Interferon-alpha; Osteosarcoma; Tumor Cells, Cultured

1999
A nude mouse model of human osteosarcoma lung metastases for evaluating new therapeutic strategies.
    Clinical & experimental metastasis, 1999, Volume: 17, Issue:6

    Topics: Animals; Antineoplastic Agents; Cytokines; Disease Models, Animal; Doxorubicin; Drug Screening Assays, Antitumor; Etoposide; Humans; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Osteosarcoma; Vinblastine

1999
The death substrate Gas2 binds m-calpain and increases susceptibility to p53-dependent apoptosis.
    The EMBO journal, 2001, Jun-01, Volume: 20, Issue:11

    Topics: Animals; Apoptosis; Calpain; Cell Line; Cell Survival; Etoposide; Genes, Reporter; Humans; Luciferases; Methyl Methanesulfonate; Mice; Mice, Inbred BALB C; Microfilament Proteins; Osteosarcoma; Recombinant Proteins; Saccharomyces cerevisiae; Sequence Deletion; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Ultraviolet Rays

2001
Additive effect of adenovirus-mediated E2F-1 gene transfer and topoisomerase II inhibitors on apoptosis in human osteosarcoma cells.
    Cancer gene therapy, 2001, Volume: 8, Issue:4

    Topics: Adenoviridae; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Bone Neoplasms; Cell Cycle; Cell Cycle Proteins; Cell Survival; DNA-Binding Proteins; Doxorubicin; E2F Transcription Factors; E2F1 Transcription Factor; Enzyme Inhibitors; Etoposide; Gene Expression; Gene Transfer Techniques; Humans; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nuclear Proteins; Osteosarcoma; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Topoisomerase II Inhibitors; Transcription Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2001
Regulation of DNAS1L3 endonuclease activity by poly(ADP-ribosyl)ation during etoposide-induced apoptosis. Role of poly(ADP-ribose) polymerase-1 cleavage in endonuclease activation.
    The Journal of biological chemistry, 2002, Jan-04, Volume: 277, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Caspases; DNA Fragmentation; Endodeoxyribonucleases; Enzyme Activation; Etoposide; Osteosarcoma; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases

2002
[An autopsy case of pulmonary and central nervous system metastatic osteosarcoma treated with thirty-six courses of chemotherapy over four years].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2002, Volume: 40, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brain Neoplasms; Carboplatin; Cisplatin; Dacarbazine; Deoxycytidine; Docetaxel; Drug Administration Schedule; Etoposide; Gemcitabine; Humans; Ifosfamide; Lung Neoplasms; Male; Methotrexate; Osteosarcoma; Paclitaxel; Spinal Cord Neoplasms; Survivors; Taxoids; Vincristine; Vindesine

2002
Treatment of refractory osteosarcoma with fractionated cyclophosphamide and etoposide.
    Journal of pediatric hematology/oncology, 2002, Volume: 24, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cyclophosphamide; Dose-Response Relationship, Drug; Etoposide; Female; Humans; Male; Neoplasm Recurrence, Local; Osteosarcoma; Retrospective Studies; Survival Rate; Treatment Outcome

2002
Primary treatment of pelvic osteosarcoma. Report of five cases.
    Cancer, 1992, Mar-01, Volume: 69, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Etoposide; Fluid Therapy; Follow-Up Studies; Humans; Ifosfamide; Injections, Intra-Arterial; Lung Neoplasms; Osteosarcoma; Pelvic Bones; Radiotherapy Dosage; Survival Rate

1992
Circumvention of pleiotropic drug resistance in subcutaneous tumours in vivo with verapamil and clomipramine.
    European journal of cancer (Oxford, England : 1990), 1991, Volume: 27, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Clomipramine; Dactinomycin; Doxorubicin; Drug Resistance; Etoposide; Female; Male; Mice; Mice, Inbred AKR; Osteosarcoma; Verapamil; Vincristine

1991
Neoadjuvant chemotherapy for nonmetastatic osteosarcoma of the extremities.
    Clinical orthopaedics and related research, 1991, Issue:270

    Topics: Adolescent; Adult; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bone Lengthening; Bone Neoplasms; Bone Transplantation; Child; Cisplatin; Combined Modality Therapy; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Ifosfamide; Italy; Male; Methotrexate; Osteosarcoma; Osteotomy; Postoperative Care; Preoperative Care; Prognosis; Prostheses and Implants; Survival Rate

1991
Etoposide, cyclophosphamide, cisplatin, and doxorubicin as neoadjuvant chemotherapy for osteosarcoma.
    Cancer, 1991, Nov-01, Volume: 68, Issue:9

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Leg; Male; Neoplasm Recurrence, Local; Osteosarcoma; Probability; Proportional Hazards Models; Remission Induction

1991
Response of osteogenic sarcoma to the combination of etoposide and cyclophosphamide as neoadjuvant chemotherapy.
    Cancer, 1990, Feb-15, Volume: 65, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cyclophosphamide; Drug Administration Schedule; Etoposide; Female; Humans; Infusions, Intravenous; Male; Osteosarcoma

1990