Page last updated: 2024-08-23

etoposide and Necrosis

etoposide has been researched along with Necrosis in 60 studies

Research

Studies (60)

TimeframeStudies, this research(%)All Research%
pre-19904 (6.67)18.7374
1990's14 (23.33)18.2507
2000's31 (51.67)29.6817
2010's10 (16.67)24.3611
2020's1 (1.67)2.80

Authors

AuthorsStudies
Angulo-Zamudio, UA; Arredondo-Beltrán, IG; Bolscher, JGM; Canizalez-Roman, A; León-Sicairos, N; Nazmi, K; Ramírez-Sánchez, DA; Velazquez-Roman, JA; Zazueta-García, JR1
Bakker, EY; Chen, DW; Demonacos, C; Krstic-Demonacos, M; Liu, J; Mutti, L; Qattan, MY; Rajendran, R; Saha, V; Schwartz, JM; Zeef, L1
Damiani, E; Doyle, AP; Solorio, JA; Wallace, HM1
Cao, L; Chen, P; Liu, Y; Ouyang, M; Tang, D; Wang, D; Xie, M; Xu, L; Yang, L; Yang, M1
Escherich, G; Hagel, C; Hartz, B; Löbel, U1
Bertin, J; Chan, FK; Gough, PJ; Moriwaki, K; Orlowski, GM1
Choi, S; Kim, JH; Kim, SG; Kwon, HK; Kwon, MC; Lee, CG; Lee, JH; Panneerselvam, S; Park, SH; Shin, HJ1
Alnemri, D; Alnemri, ES; Cingolani, G; Fernandes-Alnemri, T; Mayes, L; Rogers, C1
Mavridis, K; Scorilas, A; Talieri, M; Thomadaki, H1
Barretto, NN; Bennett, CA; Hemenway, CS; Winters, AC1
Bergamaschi, A; De Nicola, M; Gattia, DM; Ghibelli, L; Magrini, A; Nuccitelli, S; Traversa, E1
Bohndiek, SE; Brindle, KM; Gallagher, FA; Gisselsson, A; Hansson, G; Hu, DE; Jensen, PR; Karlsson, M; Kettunen, MI; Lerche, MH; Nelson, SK; Peitersen, T; Witney, TH; Zandt, RI1
Bomken, S; Chong, L; Cole, M; Davies, B; McDermott, M; Tweddle, DA; Wood, KM1
Hu, Z; Ji, M; Ji, Y; Lin, Z; Lou, H; Wang, L; Wang, Y; Yuan, H1
Herbst, RS; Isobe, T; Itasaka, S; Jacoby, JJ; Koo, PJ; Morgensztern, D; O'Reilly, MS; Onn, A; Shibuya, K; Shintani, T; Wu, W1
Hatayama, T; Ishihara, K; Saito, Y; Yamagishi, N1
Amdur, RJ; Hinerman, RW; Mendenhall, WM; Monroe, AT; Morris, CG1
Chang, I; Cho, N; Koh, JY; Lee, MS1
Baudin, B; Deslandes, B; Mailloux, A; Vaubourdolle, M1
Hashimoto, C; Masui, S; Naito, M; Tsuruo, T1
Jiang, N; Pisetsky, DS1
Beyer, J; Bokemeyer, C; Braun, T; Hartmann, JT; Hartmann, M; Pottek, T; Rachud, B; Rick, O; Schirren, J; Siegert, W; Weinknecht, S; Weissbach, L1
Bouleau, S; Costina-Parvu, I; Godefroy, N; Lemaire, C; Mignotte, B; Renaud, F; Rincheval, V; Trotot, P; Vayssière, JL1
Choi, JJ; Pisetsky, DS; Reich, CF1
Dodo, K; Katoh, M; Shimizu, T; Sodeoka, M; Takahashi, M1
Hatashita, M; Hayashi, S; Jin, ZH; Kano, E; Matsumoto, H; Shioura, H1
Curnow, A; Dittmar, H; Gould, D; Greulich, KO; Morley, N; Rapp, A; Salter, L1
Dabbas, B; Ford, CD; Gabor, F; Morgan, R1
Bellyei, S; Bognar, Z; Boronkai, A; Gallyas, F; Gasz, B; Hocsak, E; Minik, O; Sumegi, B; Szigeti, A; Varbiro, G1
Genev, ED; Grudeva-Popova, JG; Lazarova, A; Mumdjiev, IN; Spasova, MI; Stoyanova, AA1
Clotagatide, A; Dubois, F; Le Jeune, N; Perek, N; Prevot, N; Sabido, O; Vergnon, JM1
Belanger, R; Dennery, JM; Gerin-Lajoie, J; Hopkins, HS; Hugenholtz, H; Montpetit, V; Nundy, D; Prior, J; Richard, MT; Stewart, DJ1
Clemm, C; Dienemann, H; Gerl, A; Kriegmair, M; Löhrs, U; Schmeller, N; Weiss, M; Wilmanns, W1
Fujihara, M; Kyo, T; Myoken, Y; Sugata, T1
Eguchi, Y; Kamiike, W; Matsuda, H; Shimizu, S; Tsujimoto, Y; Uchiyama, Y; Waguri, S1
Bernadou, A; Chauvenet, L; Guillonneau, B; Pujade-Lauraine, E; Rodier, JM1
Fabian, I; Kravtsov, VD1
Frankfurt, OS; Robb, JA; Sugarbaker, EV; Villa, L1
Chambers, JT; Cracchiolo, B; Kohorn, EI; Odunsi, KO; Parkash, V; Peck, LL; Taylor, KJ1
Enneking, WF; Lindner, NJ; Scarborough, MT; Spanier, SS1
Gollahon, KA; Kim, C; Potter, A; Rabinovitch, PS1
Drag-Zalesińska, M; Gebarowska, E; Wysocka, T; Zabel, M1
Qi, L; Sit, KH1
Clarke, NJ; Kira, J; Nakabeppu, Y; Naylor, S; Nishioka, K; Ohyagi, Y; Tomlinson, AJ; Yamada, T; Younkin, SG1
Allen, JW; Faden, AI; Knoblach, SM1
Crawford, J; Glaspy, J; Mazanet, R; Ozer, H; Tomita, DK1
Arends, JW; de Goeij, AF; Demir Weusten, AY; Dunselman, GA; Evers, JL; Groothuis, PG1
Falcovitz, A; Goldfinger, N; Gorbunova, V; Milyavsky, M; Rotter, V; Seluanov, A; Shohat, G; Sigal, A; Zurer, I1
Corbach, S; Prescott, AR; Savill, J; Spruce, BA; Wiegand, UK1
Baudin, B; Bénéteau-Burnat, B; Bruneel, A; Grenet, K; Mailloux, A; Vaubourdolle, M1
Brand, K; Buttgereit, P; Ebert, O; Märten, A; Renoth, S; Schakowski, F; Schmidt-Wolf, IG; Schöttker, B; Schroers, R; Ziske, C1
Huigsloot, M; Mulder, GJ; Tijdens, IB; van de Water, B1
Aller, P; de Blas, E; Fernández, C; Sancho, P; Troyano, A1
Casiano, CA; Johnson, N; Molinaro, C; Wu, X1
Hotta, T; Kiya, K; Kurisu, K; Mikami, T; Nakahara, T; Ogasawara, H; Sugiyama, K; Uozumi, T1
Hughes-Davies, LT; Murray, P; Spittle, M1
Berthelot, P; Boboc, B; Carnot, F; Housset, C; Tourani, JM; Tran, A1
Dohi, H; Fujiwara, K; Hanada, M; Hatanaka, N; Kuwahara, O; Takeda, S1
Buchanan, R; Herbert, A; Jefferys, M; Lea, R; McMillan, I; Mead, G; Sweetenham, J; Thompson, J; Whitehouse, JM; Williams, CJ1
Arends, JW; Blijham, GH; Braat, SH; de Haan, J; Hoogland, HJ; van Krimpen, C1

Trials

3 trial(s) available for etoposide and Necrosis

ArticleYear
Sequential resection of residual abdominal and thoracic masses after chemotherapy for metastatic non-seminomatous germ cell tumours.
    British journal of cancer, 1994, Volume: 70, Issue:5

    Topics: Abdominal Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Etoposide; Fibrosis; Germinoma; Humans; Male; Necrosis; Seminoma; Teratoma; Testicular Neoplasms; Thoracic Neoplasms

1994
Local host response in osteosarcoma after chemotherapy referred to radiographs, CT, tumour necrosis and patient survival.
    Journal of cancer research and clinical oncology, 1998, Volume: 124, Issue:10

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Infant; Infant, Newborn; Male; Mesna; Methotrexate; Middle Aged; Necrosis; Neoadjuvant Therapy; Osteosarcoma; Predictive Value of Tests; Prognosis; Tomography, X-Ray Computed

1998
Reduction of oral mucositis by filgrastim (r-metHuG-CSF) in patients receiving chemotherapy.
    Cytokines, cellular & molecular therapy, 1999, Volume: 5, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Middle Aged; Mouth Mucosa; Necrosis; Neutropenia; Proportional Hazards Models; Prospective Studies; Recombinant Proteins; Stomatitis; Survival Analysis

1999

Other Studies

57 other study(ies) available for etoposide and Necrosis

ArticleYear
Antitumor activity of bovine lactoferrin and its derived peptides against HepG2 liver cancer cells and Jurkat leukemia cells.
    Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2023, Volume: 36, Issue:3

    Topics: Child; Cisplatin; Etoposide; Hep G2 Cells; Humans; Jurkat Cells; Lactoferrin; Liver Neoplasms; Necrosis; Peptides; Quality of Life

2023
Differential regulation of cell death pathways by the microenvironment correlates with chemoresistance and survival in leukaemia.
    PloS one, 2017, Volume: 12, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Azocines; Baculoviral IAP Repeat-Containing 3 Protein; Beclin-1; Benzhydryl Compounds; Bone Marrow Cells; Caspase 3; Caspase 8; Cell Line; Cell Line, Tumor; Culture Media, Conditioned; Dexamethasone; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Glucocorticoids; Humans; Inhibitor of Apoptosis Proteins; K562 Cells; Necrosis; Phosphorylation; Receptor-Interacting Protein Serine-Threonine Kinases; Receptors, Glucocorticoid; Signal Transduction; Topoisomerase II Inhibitors; Transcriptome; Tumor Microenvironment; Ubiquitin-Protein Ligases

2017
How reliable are in vitro IC
    Toxicology letters, 2019, Mar-01, Volume: 302

    Topics: Antineoplastic Agents; Apoptosis; Biological Assay; Brain Neoplasms; Carboplatin; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Etoposide; Glioblastoma; Humans; Inhibitory Concentration 50; Necrosis; Neurons; Paraquat; Reproducibility of Results

2019
Extracellular HMGB1 prevents necroptosis in acute myeloid leukemia cells.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 112

    Topics: Alarmins; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Survival; Etoposide; Extracellular Space; HL-60 Cells; HMGB1 Protein; Humans; Leukemia, Myeloid, Acute; Necrosis; NF-kappa B; Signal Transduction

2019
Fatal neurological side-effects with necrosis of spinal cord following nelarabine treatment in a child with relapsed T-cell acute lymphoblastic leukemia.
    American journal of hematology, 2013, Volume: 88, Issue:12

    Topics: Antimetabolites, Antineoplastic; Arabinonucleosides; Cerebellum; Child; Cyclophosphamide; Cytarabine; Etoposide; Fatal Outcome; Guillain-Barre Syndrome; Humans; Magnetic Resonance Imaging; Male; Medulla Oblongata; Methotrexate; Necrosis; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Recurrence; Seizures; Spinal Cord

2013
Differential roles of RIPK1 and RIPK3 in TNF-induced necroptosis and chemotherapeutic agent-induced cell death.
    Cell death & disease, 2015, Feb-12, Volume: 6

    Topics: Apoptosis; Cathepsins; Cell Line, Tumor; Dipeptides; Doxorubicin; Etoposide; HCT116 Cells; HT29 Cells; Humans; In Vitro Techniques; MCF-7 Cells; Necrosis; Phenylalanine; Piperazines; Receptor-Interacting Protein Serine-Threonine Kinases; Tosyl Compounds; Tumor Necrosis Factor-alpha; Vinyl Compounds

2015
Etoposide Induces Necrosis Through p53-Mediated Antiapoptosis in Human Kidney Proximal Tubule Cells.
    Toxicological sciences : an official journal of the Society of Toxicology, 2015, Volume: 148, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Adhesion; Cell Cycle; Cell Line; Cell Membrane; Cell Survival; DNA Damage; DNA Repair Enzymes; Etoposide; Gene Expression Regulation; Humans; Kidney Tubules, Proximal; Mice; Mitochondrial Dynamics; Necrosis; Organelle Biogenesis; Oxidative Stress; Reactive Oxygen Species; Topoisomerase II Inhibitors; Tumor Suppressor Protein p53

2015
Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death.
    Nature communications, 2017, 01-03, Volume: 8

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Caspase 3; Cell Membrane; Etoposide; Gene Expression Regulation; HEK293 Cells; Hep G2 Cells; Humans; Intracellular Signaling Peptides and Proteins; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Necrosis; Phosphate-Binding Proteins; Primary Cell Culture; Pyroptosis; Receptors, Estrogen; Vesicular stomatitis Indiana virus

2017
Treatment of PC3 prostate cancer cells with mitoxantrone, etoposide, doxorubicin and carboplatin induces distinct alterations in the expression of kallikreins 5 and 11.
    Thrombosis and haemostasis, 2009, Volume: 101, Issue:2

    Topics: Antineoplastic Agents; Biomarkers, Tumor; Carboplatin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Kallikreins; Male; Mitoxantrone; Necrosis; Prostatic Neoplasms; RNA, Messenger; Serine Endopeptidases; Time Factors

2009
Molecular targeting of MLL-rearranged leukemia cell lines with the synthetic peptide PFWT synergistically enhances the cytotoxic effect of established chemotherapeutic agents.
    Leukemia research, 2009, Volume: 33, Issue:7

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Cycle; Cell Proliferation; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 4; Chromosomes, Human, Pair 9; Colony-Forming Units Assay; Cytarabine; DNA-Binding Proteins; Drug Synergism; Etoposide; Gene Rearrangement; Histone-Lysine N-Methyltransferase; Humans; Leukemia; Myeloid-Lymphoid Leukemia Protein; Necrosis; Nuclear Proteins; Peptide Fragments; Transcriptional Elongation Factors; Translocation, Genetic; Tumor Cells, Cultured

2009
Effects of carbon nanotubes on human monocytes.
    Annals of the New York Academy of Sciences, 2009, Volume: 1171

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cytotoxins; Dose-Response Relationship, Drug; Etoposide; Flow Cytometry; Humans; Leukocytes, Mononuclear; Monocytes; Nanotubes, Carbon; Necrosis

2009
Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a marker of cell necrosis and treatment response in tumors.
    Proceedings of the National Academy of Sciences of the United States of America, 2009, Nov-24, Volume: 106, Issue:47

    Topics: Animals; Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Carbon Isotopes; Etoposide; Female; Fumarate Hydratase; Fumarates; Lymphoma; Malates; Mice; Mice, Inbred C57BL; Necrosis; Neoplasm Transplantation; Neoplasms; Nuclear Magnetic Resonance, Biomolecular; Tissue Extracts; Treatment Outcome

2009
Percentage tumor necrosis following chemotherapy in neuroblastoma correlates with MYCN status but not survival.
    Pediatric hematology and oncology, 2011, Volume: 28, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Cisplatin; Cyclophosphamide; Etoposide; Female; Gene Amplification; Humans; Infant; Male; N-Myc Proto-Oncogene Protein; Necrosis; Neoplasm Staging; Neuroblastoma; Nuclear Proteins; Oncogene Proteins; Pilot Projects; Remission Induction; Retrospective Studies; Survival Rate; Treatment Outcome; Vincristine

2011
A novel derivative of riccardin D induces cell death through lysosomal rupture in vitro and inhibits tumor growth in vivo.
    Cancer letters, 2013, Feb-28, Volume: 329, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytoskeletal Proteins; Cytoskeleton; Etoposide; Humans; Inhibitory Concentration 50; Lysosomes; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Necrosis; Phenyl Ethers; Stilbenes; Tumor Burden; Xenograft Model Antitumor Assays

2013
Evaluation of novel orthotopic nude mouse models for human small-cell lung cancer.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2013, Volume: 8, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Proliferation; Cisplatin; Etoposide; Humans; Irinotecan; Lung Neoplasms; Mice; Mice, Nude; Necrosis; Paclitaxel; Small Cell Lung Carcinoma; Tumor Cells, Cultured

2013
Hsp105alpha enhances stress-induced apoptosis but not necrosis in mouse embryonal f9 cells.
    Journal of biochemistry, 2002, Volume: 132, Issue:2

    Topics: Animals; Apoptosis; Caspase 3; Caspase 9; Caspases; Cell Line; Cell Survival; Cycloheximide; Cytochrome c Group; DNA Fragmentation; Embryo, Mammalian; Enzyme Precursors; Etoposide; Hot Temperature; HSP110 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinases; Necrosis; Nucleic Acid Synthesis Inhibitors; p38 Mitogen-Activated Protein Kinases; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Protein Synthesis Inhibitors; Proteins

2002
Radiation therapy for esthesioneuroblastoma: rationale for elective neck irradiation.
    Head & neck, 2003, Volume: 25, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Blindness; Bone Neoplasms; Carboplatin; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Cytarabine; Epirubicin; Esthesioneuroblastoma, Olfactory; Etoposide; Female; Humans; Lung Neoplasms; Lymphatic Irradiation; Lymphatic Metastasis; Male; Middle Aged; Nasal Cavity; Necrosis; Neoplasm Recurrence, Local; Nose Neoplasms; Radiotherapy Dosage; Radiotherapy, Adjuvant; Salvage Therapy; Spinal Cord Neoplasms; Survival Analysis

2003
Pyruvate inhibits zinc-mediated pancreatic islet cell death and diabetes.
    Diabetologia, 2003, Volume: 46, Issue:9

    Topics: Adenosine Triphosphate; Animals; Antigens, Polyomavirus Transforming; Antioxidants; Cell Death; Cell Line, Tumor; Cell Transformation, Neoplastic; Diabetes Mellitus, Experimental; Etoposide; Insulinoma; Interferon-gamma; Islets of Langerhans; NAD; Necrosis; Pancreatic Neoplasms; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Staurosporine; Tumor Necrosis Factor-alpha; Zinc

2003
Captopril and enalaprilat decrease antioxidant defences in human endothelial cells and are unable to protect against apoptosis.
    Cell biology international, 2003, Volume: 27, Issue:10

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antioxidants; Apoptosis; Captopril; Cells, Cultured; Dose-Response Relationship, Drug; Enalaprilat; Endothelium, Vascular; Etoposide; Glutathione Peroxidase; Humans; Lipid Peroxidation; Malondialdehyde; Necrosis; Oxidative Stress; Superoxide Dismutase; Umbilical Veins

2003
Caspase-independent necrotic cell death induced by a radiosensitizer, 8-nitrocaffeine.
    Cancer science, 2004, Volume: 95, Issue:4

    Topics: Antibodies, Monoclonal; Antimycin A; Caffeine; Caspases; Cell Death; Cell Hypoxia; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Drug Resistance, Multiple; Etoposide; fas Receptor; Fibrosarcoma; Free Radical Scavengers; HL-60 Cells; Humans; Jurkat Cells; K562 Cells; Necrosis; Radiation-Sensitizing Agents; Reactive Oxygen Species; U937 Cells; Xanthines

2004
The effect of dexamethasone on the generation of plasma DNA from dead and dying cells.
    The American journal of pathology, 2004, Volume: 164, Issue:5

    Topics: Animals; Antineoplastic Agents, Hormonal; Apoptosis; Dexamethasone; DNA; Dose-Response Relationship, Drug; Ethanol; Etoposide; Female; Flow Cytometry; Glucocorticoids; Humans; In Situ Nick-End Labeling; Jurkat Cells; L-Lactate Dehydrogenase; Liver; Mice; Mice, Inbred BALB C; Necrosis; Time Factors

2004
Residual tumor resection after high-dose chemotherapy in patients with relapsed or refractory germ cell cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Sep-15, Volume: 22, Issue:18

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cohort Studies; Disease-Free Survival; Etoposide; Humans; Ifosfamide; Male; Mediastinal Neoplasms; Necrosis; Neoplasm, Residual; Neoplasms, Germ Cell and Embryonal; Paclitaxel; Retroperitoneal Neoplasms; Retrospective Studies; Testicular Neoplasms

2004
Caspase-9 can antagonize p53-induced apoptosis by generating a p76(Rb) truncated form of Rb.
    Oncogene, 2005, May-05, Volume: 24, Issue:20

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Caspase 9; Caspases; Cell Line; Cell Survival; Cloning, Molecular; Enzyme Inhibitors; Etoposide; Fibroblasts; Humans; Kinetics; Models, Genetic; Necrosis; Plasmids; Protein Structure, Tertiary; Rats; Retinoblastoma Protein; Staurosporine; Temperature; Tumor Suppressor Protein p53

2005
The role of macrophages in the in vitro generation of extracellular DNA from apoptotic and necrotic cells.
    Immunology, 2005, Volume: 115, Issue:1

    Topics: Animals; Apoptosis; Cell Death; Cell Line; Coculture Techniques; Culture Media; DNA; Etoposide; Humans; Jurkat Cells; Macrophages; Mice; Molecular Weight; Necrosis; Phagocytosis; Staurosporine

2005
Inhibition of hydrogen peroxide-induced necrotic cell death with 3-amino-2-indolylmaleimide derivatives.
    Bioorganic & medicinal chemistry letters, 2005, Jun-15, Volume: 15, Issue:12

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Death; Enzyme Inhibitors; Etoposide; HL-60 Cells; Humans; Hydrogen Peroxide; Indoles; Maleimides; Molecular Structure; Necrosis; Oxidants; Protein Kinases; Structure-Activity Relationship

2005
Modification of thermosensitivity by amrubicin or amrubicinol in human lung adenocarcinoma A549 cells and the kinetics of apoptosis and necrosis induction.
    International journal of molecular medicine, 2005, Volume: 16, Issue:3

    Topics: Adenocarcinoma; Anthracyclines; Apoptosis; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Synergism; Etoposide; Hot Temperature; Humans; Lung Neoplasms; Necrosis; Time Factors

2005
UVA-induced apoptosis studied by the new apo/necro-Comet-assay which distinguishes viable, apoptotic and necrotic cells.
    Mutagenesis, 2006, Volume: 21, Issue:2

    Topics: Annexin A5; Apoptosis; Cells, Cultured; Comet Assay; DNA Fragmentation; Etoposide; Humans; In Situ Nick-End Labeling; Kinetics; Necrosis; Nucleic Acid Synthesis Inhibitors; Pesticides; Time Factors; Trypan Blue; Ultraviolet Rays

2006
False-positive restaging PET scans involving the spleen in two patients with aggressive non-Hodgkin lymphoma.
    Clinical nuclear medicine, 2006, Volume: 31, Issue:7

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Burkitt Lymphoma; Carboplatin; Cyclophosphamide; Dexamethasone; Disease Progression; Doxorubicin; Etoposide; False Positive Reactions; Humans; Ifosfamide; Laparoscopy; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Middle Aged; Necrosis; Neoplasm Staging; Positron-Emission Tomography; Prednisone; Remission Induction; Rituximab; Salvage Therapy; Spleen; Splenectomy; Tomography, X-Ray Computed; Unnecessary Procedures; Vincristine

2006
Induction of necrotic cell death and mitochondrial permeabilization by heme binding protein 2/SOUL.
    FEBS letters, 2006, Nov-27, Volume: 580, Issue:27

    Topics: Animals; Antineoplastic Agents, Phytogenic; Calcimycin; Calcium; Carrier Proteins; Cyclosporine; Etoposide; Heme-Binding Proteins; Hemeproteins; Humans; Immunosuppressive Agents; Ionophores; Mice; Mitochondria; Mitochondrial Membranes; Necrosis; NIH 3T3 Cells; Permeability; Pregnancy Proteins; Recombinant Proteins

2006
Pseudomembranous necrotizing tracheobronchitis caused by Aspergillus spp--contribution of one case with acute myeloid leukemia.
    Folia medica, 2006, Volume: 48, Issue:3-4

    Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Aspergillosis; Aspergillus; Bronchitis; Cytarabine; Etoposide; Fatal Outcome; Humans; Idarubicin; Immunocompromised Host; Leukemia, Myeloid; Lung Diseases, Fungal; Male; Necrosis; Opportunistic Infections; Radiography, Thoracic; Tracheitis

2006
Could 99mTc-glucarate be used to evaluate tumour necrosis? In vitro and in vivo studies in leukaemic tumour cell line U937.
    European journal of nuclear medicine and molecular imaging, 2008, Volume: 35, Issue:7

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Survival; Etoposide; Glucaric Acid; Humans; Lymphoma, Large B-Cell, Diffuse; Mice; Mice, Nude; Necrosis; Neoplasm Transplantation; Organotechnetium Compounds; Radionuclide Imaging; Radiopharmaceuticals; Transplantation, Heterologous; U937 Cells

2008
Penetration of VP-16 (etoposide) into human intracerebral and extracerebral tumors.
    Journal of neuro-oncology, 1984, Volume: 2, Issue:2

    Topics: Brain Neoplasms; Etoposide; Glioma; Half-Life; Humans; Kinetics; Necrosis; Neoplasms; Podophyllotoxin

1984
Oral Fusarium infection in a granulocytopenic patient with acute myelogenous leukemia: a case report.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1995, Volume: 24, Issue:5

    Topics: Acute Kidney Injury; Aged; Agranulocytosis; Amphotericin B; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Epirubicin; Etoposide; Fatal Outcome; Fusarium; Gingival Diseases; Humans; Immunocompromised Host; Leukemia, Myeloid, Acute; Male; Maxillary Diseases; Mercaptopurine; Mycoses; Necrosis; Prednisolone; Ulcer; Vindesine

1995
Bcl-2 blocks loss of mitochondrial membrane potential while ICE inhibitors act at a different step during inhibition of death induced by respiratory chain inhibitors.
    Oncogene, 1996, Jul-04, Volume: 13, Issue:1

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Apoptosis; bcl-X Protein; Calcimycin; Caspase 1; Cell Death; Cell Hypoxia; Chickens; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Electron Transport; Enzyme Inhibitors; Etoposide; Humans; Ionophores; Membrane Potentials; Mitochondria; Molecular Sequence Data; Necrosis; PC12 Cells; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Recombinant Fusion Proteins; Serpins; Sodium Cyanide; Topoisomerase II Inhibitors; Transfection; Uncoupling Agents; Viral Proteins

1996
Haemoperitoneum due to necrosis of bulky retroperitoneal metastases: an unusual complication of chemotherapy for testicular cancer.
    British journal of urology, 1996, Volume: 77, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Etoposide; Hemoperitoneum; Humans; Lymphatic Metastasis; Male; Mixed Tumor, Malignant; Necrosis; Testicular Neoplasms

1996
Automated monitoring of apoptosis in suspension cell cultures.
    Laboratory investigation; a journal of technical methods and pathology, 1996, Volume: 74, Issue:2

    Topics: Animals; Apoptosis; Automation; Cell Line; Cells, Cultured; Cisplatin; Cytological Techniques; DNA Damage; Ethanol; Etoposide; Female; HL-60 Cells; Humans; Hydrogen Peroxide; Kinetics; Mice; Mice, Inbred C57BL; Necrosis; Reproducibility of Results; Sensitivity and Specificity; Thymus Gland

1996
Monoclonal antibody to single-stranded DNA is a specific and sensitive cellular marker of apoptosis.
    Experimental cell research, 1996, Aug-01, Volume: 226, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Apoptosis; Biomarkers; Cell Line; Cisplatin; DNA, Single-Stranded; Etoposide; Fluorescent Antibody Technique, Indirect; HL-60 Cells; Humans; Immunohistochemistry; Leukemia; Mice; Necrosis; Sensitivity and Specificity; Tumor Cells, Cultured

1996
Necrosis of myometrial choriocarcinoma with fulminating sepsis complicating chemotherapy for trophoblastic tumor.
    Gynecologic oncology, 1998, Volume: 70, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Etoposide; Female; Humans; Methotrexate; Myometrium; Necrosis; Neoplasms, Multiple Primary; Pregnancy; Remission Induction; Sepsis; Trophoblastic Neoplasms; Uterine Neoplasms; Vincristine

1998
Apoptotic human lymphocytes have diminished CD4 and CD8 receptor expression.
    Cellular immunology, 1999, Apr-10, Volume: 193, Issue:1

    Topics: Apoptosis; CD3 Complex; CD4 Antigens; CD8 Antigens; Cycloheximide; Etoposide; Humans; Lymphocytes; Necrosis; Transglutaminases

1999
Evaluation of apoptosis and necrosis induction in cultured cells of lung carcinomas under effect of cytostatic drugs in vitro.
    Folia histochemica et cytobiologica, 1999, Volume: 37, Issue:2

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Bleomycin; Carcinoma, Non-Small-Cell Lung; Cisplatin; Epirubicin; Etoposide; Humans; Lung Neoplasms; Methotrexate; Necrosis; Tumor Cells, Cultured; Vinblastine; Vincristine

1999
CpG-specific common commitment in caspase-dependent and -independent cell deaths.
    Molecular cell biology research communications : MCBRC, 2000, Volume: 3, Issue:1

    Topics: Amino Acid Chloromethyl Ketones; Annexin A5; Apoptosis; Caspase Inhibitors; Caspases; Cell Line; CpG Islands; Cysteine Proteinase Inhibitors; DNA Fragmentation; Enzyme Inhibitors; Etoposide; fas Receptor; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Necrosis; Nucleic Acid Synthesis Inhibitors; Oligonucleotides; Phosphatidylserines; Time Factors; Tumor Cells, Cultured

2000
Selective increase in cellular A beta 42 is related to apoptosis but not necrosis.
    Neuroreport, 2000, Jan-17, Volume: 11, Issue:1

    Topics: Amyloid beta-Peptides; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Apoptosis; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Etoposide; Guinea Pigs; Humans; Hydrogen Peroxide; Immunohistochemistry; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Melphalan; Necrosis; Peptide Fragments; Reactive Oxygen Species; Sodium Azide

2000
Activation of group I metabotropic glutamate receptors reduces neuronal apoptosis but increases necrotic cell death in vitro.
    Cell death and differentiation, 2000, Volume: 7, Issue:5

    Topics: Animals; Apoptosis; Cell Hypoxia; Cells, Cultured; Etoposide; Models, Neurological; Necrosis; Neurons; Rats; Receptors, Metabotropic Glutamate; Staurosporine

2000
Morphological changes in mesothelial cells induced by shed menstrual endometrium in vitro are not primarily due to apoptosis or necrosis.
    Human reproduction (Oxford, England), 2000, Volume: 15, Issue:7

    Topics: Annexin A5; Apoptosis; Cell Line; Cells, Cultured; Culture Media, Conditioned; DNA; Endometrium; Epithelial Cells; Etoposide; Female; Flow Cytometry; Humans; Menstruation; Necrosis; Omentum

2000
Change of the death pathway in senescent human fibroblasts in response to DNA damage is caused by an inability to stabilize p53.
    Molecular and cellular biology, 2001, Volume: 21, Issue:5

    Topics: Acridine Orange; Antibiotics, Antineoplastic; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Separation; Cells, Cultured; Cellular Senescence; Cisplatin; Cysteine Endopeptidases; Dactinomycin; DNA Damage; Electrophoresis, Polyacrylamide Gel; Etoposide; Fibroblasts; Flow Cytometry; Fluorescent Dyes; Humans; Models, Biological; Multienzyme Complexes; Necrosis; Nucleic Acid Synthesis Inhibitors; Proteasome Endopeptidase Complex; Time Factors; Transfection; Tumor Suppressor Protein p53; Ultraviolet Rays

2001
The trigger to cell death determines the efficiency with which dying cells are cleared by neighbours.
    Cell death and differentiation, 2001, Volume: 8, Issue:7

    Topics: Apoptosis; bcl-2-Associated X Protein; Caspases; Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; Etoposide; Humans; Microscopy, Fluorescence; Mutation; Necrosis; Organ Specificity; Phagocytes; Phagocytosis; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Staurosporine; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2001
Anticancer drugs induce necrosis of human endothelial cells involving both oncosis and apoptosis.
    European journal of cell biology, 2001, Volume: 80, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Bleomycin; Cells, Cultured; DNA Damage; Dose-Response Relationship, Drug; Doxorubicin; Endothelium, Vascular; Etoposide; Glutathione; Humans; Immunohistochemistry; L-Lactate Dehydrogenase; Malondialdehyde; Necrosis; Oxidative Stress; Paclitaxel; Peptidyl-Dipeptidase A; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Suppressor Protein p53; Umbilical Veins

2001
Effects of adenoviral wild-type p53 gene transfer in p53-mutated lymphoma cells.
    Cancer gene therapy, 2001, Volume: 8, Issue:6

    Topics: Adenoviridae; Apoptosis; Cell Division; Cell Line; Etoposide; Flow Cytometry; Gene Transfer Techniques; Genes, p53; Green Fluorescent Proteins; Humans; Immunoblotting; Killer Cells, Natural; Luminescent Proteins; Lymphoma; Microscopy, Fluorescence; Mutation; Necrosis; Protein Synthesis Inhibitors; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Transduction, Genetic; Transfection

2001
Differential regulation of phosphatidylserine externalization and DNA fragmentation by caspases in anticancer drug-induced apoptosis of rat mammary adenocarcinoma MTLn3 cells.
    Biochemical pharmacology, 2001, Oct-15, Volume: 62, Issue:8

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Caspases; Cisplatin; DNA Fragmentation; Doxorubicin; Etoposide; Exocytosis; Mammary Neoplasms, Animal; Necrosis; Phosphatidylserines; Rats; Tumor Cells, Cultured

2001
Effect of glutathione depletion on antitumor drug toxicity (apoptosis and necrosis) in U-937 human promonocytic cells. The role of intracellular oxidation.
    The Journal of biological chemistry, 2001, Dec-14, Volume: 276, Issue:50

    Topics: Adenosine Triphosphate; Alkylating Agents; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Buthionine Sulfoximine; Camptothecin; Cell Death; Cisplatin; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Doxorubicin; Enzyme Inhibitors; Etoposide; Flow Cytometry; Glutathione; Humans; Hydrogen Peroxide; Hypoxia; Immunoblotting; Melphalan; Membrane Potentials; Mitochondria; Monocytes; Necrosis; Nucleic Acid Synthesis Inhibitors; Oxygen; Radiation-Protective Agents; Reactive Oxygen Species; Spectrometry, Fluorescence; Time Factors; Topoisomerase I Inhibitors; U937 Cells

2001
Secondary necrosis is a source of proteolytically modified forms of specific intracellular autoantigens: implications for systemic autoimmunity.
    Arthritis and rheumatism, 2001, Volume: 44, Issue:11

    Topics: Amino Acid Chloromethyl Ketones; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Apoptosis; Autoantigens; Caspases; DNA Topoisomerases, Type I; Drug Combinations; Etoposide; HeLa Cells; Humans; Jurkat Cells; Necrosis; Poly(ADP-ribose) Polymerases; Ribonucleoprotein, U1 Small Nuclear; Staurosporine

2001
Effect of intracarotid infusion of etoposide with angiotensin II-induced hypertension on the blood-brain barrier and the brain tissue.
    Journal of neuro-oncology, 1992, Volume: 13, Issue:2

    Topics: Angiotensin II; Animals; Atrophy; Blood-Brain Barrier; Brain; Brain Edema; Carotid Arteries; Demyelinating Diseases; Etoposide; Evans Blue; Hypertension; Infusions, Intra-Arterial; Male; Necrosis; Rats; Rats, Inbred F344

1992
Fournier's gangrene: a hazard of chemotherapy in AIDS.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 1991, Volume: 3, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; Etoposide; Fasciitis; Gangrene; Humans; Male; Necrosis; Neutropenia; Perineum; Sarcoma, Kaposi; Scrotum; Skin Neoplasms

1991
Etoposide (VP 16-213) induced hepatitis. Report of three cases following standard-dose treatments.
    Journal of hepatology, 1991, Volume: 12, Issue:1

    Topics: Acute Disease; Aged; Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Etoposide; Female; Humans; Liver; Male; Middle Aged; Necrosis; Neoplasms

1991
[A case of chemotherapy induced necrosis of primary mediastinal germ cell tumor].
    [Zasshi] [Journal]. Nihon Kyobu Geka Gakkai, 1989, Volume: 37, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Etoposide; Humans; Male; Mediastinal Neoplasms; Mesonephroma; Necrosis; Peplomycin; Remission Induction

1989
Surgery after initial chemotherapy for localized small-cell carcinoma of the lung.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:10

    Topics: Actuarial Analysis; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Necrosis; Neoplasm Staging; Prospective Studies

1987
Death from chemotherapy in gestational trophoblastic disease.
    European journal of obstetrics, gynecology, and reproductive biology, 1988, Volume: 29, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Choriocarcinoma; Cyclophosphamide; Etoposide; Female; Humans; Lung Neoplasms; Methotrexate; Necrosis; Pregnancy; Pulmonary Embolism; Uterine Neoplasms

1988