Page last updated: 2024-08-23

etoposide and Malignant Melanoma

etoposide has been researched along with Malignant Melanoma in 78 studies

Research

Studies (78)

TimeframeStudies, this research(%)All Research%
pre-199012 (15.38)18.7374
1990's22 (28.21)18.2507
2000's27 (34.62)29.6817
2010's16 (20.51)24.3611
2020's1 (1.28)2.80

Authors

AuthorsStudies
Bastow, KF; Cheng, HH; Ito, J; Lee, KH; Luo, TY; Nakanishi, Y; Tachibana, Y; Wang, HK; Xu, Z1
Amin, S; Gowda, ASP; Karelia, DN; Pandey, MK; Ramisetti, SR; Sharma, AK; Singh, P; Sk, UH1
Brouard, I; Estévez, F; Estévez-Sarmiento, F; García, C; León, F; Quintana, J; Said, M1
Chuang, YJ; Liu, LY; Shyu, YM1
Choi, DK; DiPatri, AJ; Lulla, RR; Marzec, S; Pillay-Smiley, N; Tomita, T; Wadhwani, NR1
D de Araujo, A; Fairlie, DP; Good, AC; Lim, J; Skerlj, R; Wu, KC; Xiang, Y1
Nakagawa, T; Nishimura, R; Ong, SM; Saeki, K; Tanaka, Y; Yamamoto, H; Yoshitake, R1
Bhattacharjee, S; Espey, MG; Kumar, A; Mason, RP; Sinha, BK1
Chakraborty, A; De, A; Patravale, V; Pawar, Y; Sable, S; Selkar, N; Shete, H; Tidke, P; Vanage, G1
Ferracini, M; Sahu, RP; Travers, JB1
Becatti, M; Bianchini, F; Calorini, L; Calvani, M; Chiarugi, P; Giannoni, E; Taddei, ML1
Hayakawa, Y; Ma, H; Saiki, I; Yokoyama, S1
Cervinka, M; Rudolf, E; Rudolf, K2
Baraldi, PG; Borea, PA; Gessi, S; Merighi, S; Mirandola, P; Simioni, C; Tabrizi, MA; Varani, K1
Aplin, AE; Hu, R1
Anwar, A; Fujita, M; Norris, DA1
Craig, EA; Spiegelman, VS1
Chang, HC; De La Rosa, M; Han, L; Lupov, IP; Oza, K; Pelloso, D; Robertson, MJ; Sahu, RP; Schwartz, A; Travers, JB; Voiles, L1
Calvani, M; Chiarugi, P; Comito, G; Giannoni, E1
Ball, KL; Dornan, D; Kelleher, M; Pamment, J; Ramsay, E1
Gschwendt, B; Helmbach, H; Kioschis, P; Korn, B; Lichter, P; Mollenhauer, J; Münstermann, E; Nessling, M; Poustka, A; Salowsky, R; Schadendorf, D; Schick, M; Will, RD; Wittig, R1
Hancock, R; Kumala, S; Niemiec, P; Rzeszowska-Wolny, J; Wideł, M1
Hao, C; Herlyn, M; Petruk, KC; Song, DK; Song, JH1
Gude, RP; Nagarsenker, MS; Rao, SG; Sant, VP1
Bae, JH; Chung, BS; Ju, DS; Kang, CD; Kim, DW; Kim, MJ; Kim, SH; Kwon, JK; Um, JH1
Campi, V; Chiodini, E; Daniotti, M; Di Stasi, D; Fiorentini, S; Greeve, I; Pierotti, MA; Prinetti, A; Ranzani, T; Rivoltini, L; Rodolfo, M; Vallacchi, V1
Jiao, W; Lin, HM; Misteli, T; Nagaich, AK; Ng, SW; Rane, SG; Timmons, J1
Cuq, P; Depeille, P; Evrard, A; Passagne, I; Vian, L1
Daniel, PT; Eberle, J; Fecker, LF; Geilen, CC; Gillissen, B; Oppermann, M1
Alberts, SR; Erlichman, C; Furth, A; Lathia, CD; Molina, JR; Reid, JM; Safgren, SL; Sloan, JA1
Kissel, CK; Röckmann, H; Schadendorf, D1
Bernardini, S; Federici, G; Gravina, P; Valentini, A1
Campbell, RB; Dandamudi, S1
Campain, JA; Gottesman, MM; Pastan, I1
Asko-Seljavaara, S; Franssila, K; Kangas, L; Laasonen, A; Muhonen, T; Pyrhönen, S; Wasenius, VM1
Bussey, AM; Ng, CE; Raaphorst, GP1
Campain, JA; Gottesman, MM; Hwang, J; Padmanabhan, R; Pastan, I1
Mimnaugh, EG; Monti, E; Sinha, BK1
Campain, JA; Gottesman, MM; Pastan, I; Popescu, NC; Schoenlein, PV; Slovak, ML1
Guichard, M; Lartigau, E1
Deegan, WF; Fisher, A; Gomer, CJ; Malogolowkin, M; Murphree, AL; Parker, R; Reed, E; Sato, JK; Villablanca, JG1
de Boer-Dennert, M; Goey, SH; Planting, AS; Schellens, JH; Stoter, G; van der Burg, ME; Vecht, C; Verweij, J1
Berger, W; Elbling, L; Hauptmann, E; Kokoschka, EM; Micksche, M; Vetterlein, M1
Broadbent, JL; Dreosti, IE; Head, RJ; King, RA; Record, IR; Tonkin, AL1
Aoyagi, K; Aoyagi, Y; Asao, T; Okazaki, S; Sano, M; Utsugi, T; Wierzba, K; Yamada, Y1
Egorova, NI; Garin, AM; Gorozhanskaia, EG; Koroleva, EIu; Kushlinskiĭ, NE; Larionova, VB1
Christmann, M; Dietel, M; Kaina, B; Kern, MA; Lage, H; Pick, M; Schadendorf, D1
Boni, C; Carlini, P; Cocconi, G; Di Costanzo, F; Di Sarra, S; Fosser, V; Franciosi, V; Michiara, M; Tonato, M1
Nieder, C1
Diem, C; Emmert, S; Epe, B; Hellfritsch, D; Rünger, TM; Schadendorf, D1
Dietel, M; Helmbach, H; Lage, H; Schadendorf, D1
Dong, H; Hirpara, JL; Kini, RM; Loh, KW; Pervaiz, S; Seyed, MA1
Kern, MA; Lichter, P; Nessling, M; Schadendorf, D1
Baudouin, C; Casagrande, F; Darbon, JM; Ducommun, B; Escalas, N; Goubin-Gramatica, F; Penary, M1
Dietel, M; Grottke, C; Lage, H; Mantwill, K; Schadendorf, D1
Darbon, JM; Nebreda, AR; Pillaire, MJ1
Dietel, M; Grottke, C; Helmbach, H; Lage, H; Schadendorf, D1
Dong, YB; Elliott, MJ; McMasters, KM; Yang, HL1
Gschwendt, B; Helmbach, H; Kern, MA; Kissel, C; Renz, K; Rossmann, E; Schadendorf, D1
Bergman, S; Creager, AJ; Geisinger, KR1
Adamson, RH; Mead, JA; Sieber, SM1
Barlogie, B; Corry, PM; Dosik, G; Freireich, EJ; Hankenson, R; Johnston, DA; Khalil, K; Lawson, R; Lippman, L; Reilly, E; Rigor, B; Tenczynski, TF; Yip, E1
Al-Sarraf, M; Cecil, JW; Coltman, CA; Groppe, CW; Quagliana, JM; Thigpen, T1
Ahmann, DL; Bisel, HF; Edmonson, JH; Frytak, S; Hahn, RG; O'Connell, MJ1
Kubota, K; Kubota, R; Yamada, S1
Baguley, BC; Finlay, GJ1
Mimnaugh, EG; Sinha, BK; Usui, N2
Bajorin, DF; Chapman, PB; Cody, BV; Eton, O; Houghton, AN1
Alberts, DS; Asbury, RF; Boros, L; Goodman, TL; Hickox, DE; Peng, YM; Penn, TE1
Brown, JM; Etiz, BB; Newman, RA; Raffin, TA; Sikic, BI; Zuckerman, JE1
Lönn, S; Lönn, U; Nylen, U; Winblad, G1
Ajani, JA; Baker, FL; Blaauw, AA; Dicke, KA; Spitzer, G; Thielvoldt, D; Tomasovic, B; Umbach, G; Zander, AR1
Engelhardt, R1
Peters, W; Souhami, R1
Roseman, JM1
Bajetta, E; Bonadonna, G; Buzzoni, R; Nava, M; Vaglini, M; Viviani, S1

Reviews

3 review(s) available for etoposide and Malignant Melanoma

ArticleYear
Primary Central Nervous System Malignant Melanoma in Children: A Case Series and Review of the Literature.
    Journal of pediatric hematology/oncology, 2018, Volume: 40, Issue:8

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Chemoradiotherapy; Child, Preschool; Etoposide; Humans; Ipilimumab; Male; Melanoma; Temozolomide

2018
Pharmacology of antitumor agents from higher plants.
    Cancer treatment reports, 1976, Volume: 60, Issue:8

    Topics: Animals; Antineoplastic Agents, Phytogenic; Aporphines; Camptothecin; Carcinoma, Squamous Cell; Chemical Phenomena; Chemistry; Etoposide; Humans; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymphoid; Maytansine; Melanoma; Naphthoquinones; Nasopharyngeal Neoplasms; Neoplasms; Neoplasms, Experimental; Phenanthrenes; Structure-Activity Relationship; Teniposide; Vinblastine; Vincristine

1976
High dose chemotherapy in solid tumours in adults.
    Clinics in haematology, 1986, Volume: 15, Issue:1

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Breast Neoplasms; Carcinoma, Small Cell; Carmustine; Cell Separation; Cisplatin; Colonic Neoplasms; Cyclophosphamide; Etoposide; Glioma; Humans; Lung Neoplasms; Male; Melanoma; Melphalan; Neoplasms; Testicular Neoplasms; Whole-Body Irradiation

1986

Trials

6 trial(s) available for etoposide and Malignant Melanoma

ArticleYear
A phase I and pharmacokinetic study of the selective, non-peptidic inhibitor of matrix metalloproteinase BAY 12-9566 in combination with etoposide and carboplatin.
    Anti-cancer drugs, 2005, Volume: 16, Issue:9

    Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Biphenyl Compounds; Carboplatin; Cohort Studies; Colonic Neoplasms; Enzyme Inhibitors; Etoposide; Female; Humans; Male; Matrix Metalloproteinase Inhibitors; Melanoma; Middle Aged; Neoplasms; Neoplasms, Unknown Primary; Neutropenia; Organic Chemicals; Phenylbutyrates; Thrombocytopenia; Thymoma; Treatment Outcome; Vomiting

2005
Phase II study of a short course of weekly high-dose cisplatin combined with long-term oral etoposide in metastatic malignant melanoma.
    European journal of cancer (Oxford, England : 1990), 1996, Volume: 32A, Issue:11

    Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Etoposide; Female; Humans; Male; Melanoma; Middle Aged; Skin Neoplasms

1996
Front-line chemotherapy with cisplatin and etoposide for patients with brain metastases from breast carcinoma, nonsmall cell lung carcinoma, or malignant melanoma: a prospective study.
    Cancer, 1999, Apr-01, Volume: 85, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cisplatin; Etoposide; Female; Humans; Lung Neoplasms; Melanoma; Middle Aged; Prospective Studies; Survival Rate

1999
Phase II study of VP-16-213 versus dianhydrogalactitol in patients with metastatic malignant melanoma.
    Cancer treatment reports, 1976, Volume: 60, Issue:11

    Topics: Drug Evaluation; Drug Therapy, Combination; Ethers, Cyclic; Etoposide; Female; Galactitol; Humans; Male; Melanoma; Podophyllotoxin; Sugar Alcohols

1976
Phase II trial of cisplatin and etoposide in patients with metastatic melanoma.
    Investigational new drugs, 1991, Volume: 9, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Evaluation; Etoposide; Female; Humans; Male; Melanoma; Middle Aged

1991
Prospective randomized trial in advanced malignant melanoma with cis-platinum, vindesine, and etoposide vs. cis-platinum, vindesine, and lomustine.
    American journal of clinical oncology, 1985, Volume: 8, Issue:5

    Topics: Adult; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Etoposide; Female; Humans; Leukopenia; Lomustine; Male; Melanoma; Middle Aged; Nausea; Neoplasm Metastasis; Prospective Studies; Random Allocation; Skin Neoplasms; Thrombocytopenia; Vindesine; Vomiting

1985

Other Studies

69 other study(ies) available for etoposide and Malignant Melanoma

ArticleYear
Cytotoxic pheophorbide-related compounds from Clerodendrum calamitosum and C. cyrtophyllum.
    Journal of natural products, 2001, Volume: 64, Issue:7

    Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Camptothecin; Cell Survival; Chlorophyll; Dose-Response Relationship, Drug; Drug Resistance; Etoposide; Female; Humans; Ileal Neoplasms; KB Cells; Kidney Neoplasms; Lung Neoplasms; Magnetic Resonance Spectroscopy; Melanoma; Molecular Structure; Ovarian Neoplasms; Plant Leaves; Plant Stems; Plants, Medicinal; Stereoisomerism; Structure-Activity Relationship; Taiwan; Tumor Cells, Cultured; Vincristine

2001
Design, synthesis, and identification of a novel napthalamide-isoselenocyanate compound NISC-6 as a dual Topoisomerase-IIα and Akt pathway inhibitor, and evaluation of its anti-melanoma activity.
    European journal of medicinal chemistry, 2017, Jul-28, Volume: 135

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type II; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Melanoma; Molecular Structure; Naphthalenes; Nitriles; Proto-Oncogene Proteins c-akt; Structure-Activity Relationship

2017
3'-Hydroxy-3,4'-dimethoxyflavone blocks tubulin polymerization and is a potent apoptotic inducer in human SK-MEL-1 melanoma cells.
    Bioorganic & medicinal chemistry, 2017, 11-01, Volume: 25, Issue:21

    Topics: Apoptosis; Cell Cycle; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Flavones; Humans; Melanoma; Microscopy, Fluorescence; Molecular Structure; Polymerization; Structure-Activity Relationship; Tubulin; Tumor Cells, Cultured

2017
Synergistic Effect of Simultaneous versus Sequential Combined Treatment of Histone Deacetylase Inhibitor Valproic Acid with Etoposide on Melanoma Cells.
    International journal of molecular sciences, 2021, Sep-17, Volume: 22, Issue:18

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Survival; Drug Synergism; Etoposide; G2 Phase Cell Cycle Checkpoints; Histone Deacetylase Inhibitors; Humans; Melanoma; Valproic Acid

2021
Bicyclic Helical Peptides as Dual Inhibitors Selective for Bcl2A1 and Mcl-1 Proteins.
    Journal of medicinal chemistry, 2018, 04-12, Volume: 61, Issue:7

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Bridged Bicyclo Compounds; Cell Death; Cell Line, Tumor; Drug Design; Drug Synergism; Etoposide; Humans; Melanoma; Minor Histocompatibility Antigens; Myeloid Cell Leukemia Sequence 1 Protein; Peptides; Proto-Oncogene Proteins c-bcl-2; Rats; Structure-Activity Relationship; U937 Cells

2018
Anti-neoplastic effects of topoisomerase inhibitors in canine mammary carcinoma, melanoma, and osteosarcoma cell lines.
    The Japanese journal of veterinary research, 2017, Volume: 65, Issue:1

    Topics: Animals; Antineoplastic Agents; Carcinoma; Cell Line, Tumor; Dog Diseases; Dogs; Etoposide; Female; Mammary Neoplasms, Animal; Melanoma; Mice; Neoplasms, Experimental; Osteosarcoma; Topoisomerase Inhibitors

2017
Effect of nitric oxide on the anticancer activity of the topoisomerase-active drugs etoposide and adriamycin in human melanoma cells.
    The Journal of pharmacology and experimental therapeutics, 2013, Volume: 347, Issue:3

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Blotting, Western; Caspase 3; Cell Line, Tumor; Cell Survival; DNA Topoisomerases; Doxorubicin; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Etoposide; Humans; Lysine; Macrophages; Melanoma; Nitric Oxide; Nitric Oxide Synthase

2013
Mono-guanidine heterolipid based SMEDDS: A promising tool for cytosolic delivery of antineoplastics.
    Biomaterials, 2015, Volume: 57

    Topics: Animals; Antineoplastic Agents; Biological Availability; Cell Line, Tumor; Cell Proliferation; Drug Carriers; Drug Delivery Systems; Emulsions; Etoposide; Female; Guanidine; Lipids; Melanoma; Mice, Inbred C57BL; Solubility

2015
Systemic chemotherapy is modulated by platelet-activating factor-receptor agonists.
    Mediators of inflammation, 2015, Volume: 2015

    Topics: Animals; Antineoplastic Agents; Antioxidants; Etoposide; Female; Immunosuppression Therapy; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasm Transplantation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Signal Transduction

2015
Etoposide-Bevacizumab a new strategy against human melanoma cells expressing stem-like traits.
    Oncotarget, 2016, Aug-09, Volume: 7, Issue:32

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Cell Line, Tumor; Drug Resistance, Neoplasm; Etoposide; Female; Flow Cytometry; Humans; Melanoma; Mice; Mice, SCID; Neoplasm Metastasis; Neoplastic Stem Cells; Skin Neoplasms; Xenograft Model Antitumor Assays

2016
Chemosensitizing Effect of Saikosaponin B on B16F10 Melanoma Cells.
    Nutrition and cancer, 2017, Volume: 69, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Death; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Etoposide; Melanoma; Mice; NF-kappa B; Oleanolic Acid; Saponins; Signal Transduction

2017
Cytotoxicity and mitochondrial apoptosis induced by etoposide in melanoma cells.
    Cancer investigation, 2009, Volume: 27, Issue:7

    Topics: Adenosine Triphosphate; Antineoplastic Agents, Phytogenic; Apoptosis; Ataxia Telangiectasia Mutated Proteins; bcl-2-Associated X Protein; Benzothiazoles; Caspase 2; Caspase 3; Caspase 9; Caspase Inhibitors; Cell Cycle Proteins; Cyclosporine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA Damage; DNA-Binding Proteins; Etoposide; Humans; Melanoma; Mitochondria; Neoplasm Proteins; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Superoxides; Toluene; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

2009
A(2B) and A(3) adenosine receptors modulate vascular endothelial growth factor and interleukin-8 expression in human melanoma cells treated with etoposide and doxorubicin.
    Neoplasia (New York, N.Y.), 2009, Volume: 11, Issue:10

    Topics: Blotting, Western; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Doxorubicin; Enzyme-Linked Immunosorbent Assay; Etoposide; Flow Cytometry; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Interleukin-8; MAP Kinase Signaling System; Melanoma; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptor, Adenosine A3; Receptors, Purinergic P1; RNA Interference; Vascular Endothelial Growth Factor A

2009
alphaB-crystallin is mutant B-RAF regulated and contributes to cyclin D1 turnover in melanocytic cells.
    Pigment cell & melanoma research, 2010, Volume: 23, Issue:2

    Topics: alpha-Crystallin B Chain; Bleomycin; Butadienes; Cells, Cultured; Cyclin D1; Cycloheximide; DNA Damage; Etoposide; Humans; Leupeptins; Melanocytes; Melanoma; Mutant Proteins; Mutation; Nitriles; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Structure-Activity Relationship; Tetracycline

2010
Dual inhibition of topoisomerases enhances apoptosis in melanoma cells.
    Neoplasma, 2010, Volume: 57, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Caspases; Cell Proliferation; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Etoposide; Humans; Immunoblotting; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Melanoma; Membrane Potential, Mitochondrial; Mutation; Oxidative Stress; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2010
Ubiquitin proteasomal pathway mediated degradation of p53 in melanoma.
    Archives of biochemistry and biophysics, 2011, Apr-15, Volume: 508, Issue:2

    Topics: Animals; Cell Line, Tumor; Etoposide; G1 Phase; Gene Deletion; Genes, p16; Half-Life; Humans; Lactones; Leupeptins; Melanocytes; Melanoma; Mice; Mice, Transgenic; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Stability; Tumor Suppressor Protein p53; Ubiquitin

2011
Inhibition of coding region determinant binding protein sensitizes melanoma cells to chemotherapeutic agents.
    Pigment cell & melanoma research, 2012, Volume: 25, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Dacarbazine; Down-Regulation; Drug Resistance, Neoplasm; Etoposide; Gene Knockdown Techniques; Humans; Melanoma; Microphthalmia-Associated Transcription Factor; Neoplasm Proteins; RNA-Binding Proteins; RNA, Small Interfering; Temozolomide; Vinblastine

2012
Acquired STAT4 deficiency as a consequence of cancer chemotherapy.
    Blood, 2011, Dec-01, Volume: 118, Issue:23

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Boronic Acids; Bortezomib; Carmustine; Cells, Cultured; Drug Interactions; Etoposide; Flow Cytometry; Gene Expression; Humans; Interleukin-12; Interleukin-2; Leukocytes, Mononuclear; Lymphoma; Melanoma; Mice; Mice, Inbred C57BL; Protein Biosynthesis; Pyrazines; RNA Stability; Skin Neoplasms; STAT4 Transcription Factor; Ubiquitin

2011
Time-dependent stabilization of hypoxia inducible factor-1α by different intracellular sources of reactive oxygen species.
    PloS one, 2012, Volume: 7, Issue:10

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Phytogenic; Apoptosis; Bevacizumab; Blotting, Western; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Electron Transport Complex III; Etoposide; Humans; Hydrogen Peroxide; Hypoxia-Inducible Factor 1, alpha Subunit; Intracellular Space; Melanoma; Oxidation-Reduction; Protein Stability; Reactive Oxygen Species; RNA Interference; Rotenone; Time Factors; Uncoupling Agents; Vascular Endothelial Growth Factor A

2012
Regulation of the IRF-1 tumour modifier during the response to genotoxic stress involves an ATM-dependent signalling pathway.
    Oncogene, 2002, Nov-07, Volume: 21, Issue:51

    Topics: Androstadienes; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cycloheximide; DNA; DNA Damage; DNA-Binding Proteins; Enzyme Inhibitors; Etoposide; Fibroblasts; Gamma Rays; Genes, p53; Genes, Reporter; Humans; Interferon Regulatory Factor-1; Melanoma; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Poly I-C; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Recombinant Fusion Proteins; RNA, Messenger; Signal Transduction; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Wortmannin

2002
Candidate genes for cross-resistance against DNA-damaging drugs.
    Cancer research, 2002, Nov-15, Volume: 62, Issue:22

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Northern; Cisplatin; Cluster Analysis; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Nitrosourea Compounds; Nucleic Acid Hybridization; Organophosphorus Compounds; Tumor Cells, Cultured

2002
Apoptosis and clonogenic survival in three tumour cell lines exposed to gamma rays or chemical genotoxic agents.
    Cellular & molecular biology letters, 2003, Volume: 8, Issue:3

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Survival; Cisplatin; Clone Cells; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Etoposide; Gamma Rays; HL-60 Cells; Humans; Kinetics; Melanoma; Micronucleus Tests; Rats; Rhabdomyosarcoma

2003
Cisplatin down-regulation of cellular Fas-associated death domain-like interleukin-1beta-converting enzyme-like inhibitory proteins to restore tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human melanoma cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Sep-15, Volume: 9, Issue:11

    Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Camptothecin; Caspases; Cell Line, Tumor; Cisplatin; Etoposide; Flow Cytometry; Humans; Melanoma; Membrane Glycoproteins; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha

2003
Sterically stabilized etoposide liposomes: evaluation of antimetastatic activity and its potentiation by combination with sterically stabilized pentoxifylline liposomes in mice.
    Cancer biotherapy & radiopharmaceuticals, 2003, Volume: 18, Issue:5

    Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Disease Progression; Drug Therapy, Combination; Etoposide; Female; Liposomes; Lung Neoplasms; Male; Melanoma; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasm Transplantation; Pentoxifylline

2003
Relationship between antiapoptotic molecules and metastatic potency and the involvement of DNA-dependent protein kinase in the chemosensitization of metastatic human cancer cells by epidermal growth factor receptor blockade.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:3

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Line, Tumor; DNA-Activated Protein Kinase; DNA-Binding Proteins; Drug Synergism; Electrophoretic Mobility Shift Assay; ErbB Receptors; Etoposide; Genes, MDR; Humans; Indicators and Reagents; Melanoma; Neoplasm Metastasis; Nuclear Proteins; Protein Serine-Threonine Kinases; Pyrimidines; Pyrroles; Radiation-Sensitizing Agents; Rats

2004
DHCR24 gene expression is upregulated in melanoma metastases and associated to resistance to oxidative stress-induced apoptosis.
    International journal of cancer, 2005, Jun-10, Volume: 115, Issue:2

    Topics: Androstenes; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Northern; Cholesterol; Cisplatin; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Hydrogen Peroxide; Melanoma; Nerve Tissue Proteins; Oxidants; Oxidative Stress; Oxidoreductases Acting on CH-CH Group Donors; RNA, Messenger; Skin Neoplasms; Tumor Cells, Cultured; Up-Regulation

2005
E2F-dependent repression of topoisomerase II regulates heterochromatin formation and apoptosis in cells with melanoma-prone mutation.
    Cancer research, 2005, May-15, Volume: 65, Issue:10

    Topics: Animals; Apoptosis; Cell Cycle Proteins; Cell Line, Tumor; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinases; DNA-Binding Proteins; Doxorubicin; E2F Transcription Factors; Etoposide; Heterochromatin; Humans; Male; Melanoma; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Promoter Regions, Genetic; Proto-Oncogene Proteins; Topoisomerase II Inhibitors; Transcription Factors

2005
Combined effects of GSTP1 and MRP1 in melanoma drug resistance.
    British journal of cancer, 2005, Jul-25, Volume: 93, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Down-Regulation; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Gene Expression Profiling; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Isoenzymes; Melanoma; Multidrug Resistance-Associated Proteins; RNA, Antisense; Skin Neoplasms; Tumor Cells, Cultured

2005
Caspase-independent induction of apoptosis in human melanoma cells by the proapoptotic Bcl-2-related protein Nbk / Bik.
    Oncogene, 2005, Nov-10, Volume: 24, Issue:49

    Topics: Animals; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Caspases; Chromatin; Cytochromes c; Diphosphonates; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; fas Receptor; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; In Situ Nick-End Labeling; Injections, Subcutaneous; Melanoma; Mice; Mice, Inbred BALB C; Mice, Nude; Pamidronate; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-bcl-2; Skin; Tetracycline; Tumor Cells, Cultured

2005
The altered apoptotic pathways in cisplatin and etoposide-resistant melanoma cells are drug specific.
    Melanoma research, 2006, Volume: 16, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Caspases; Cisplatin; Cytochromes c; Drug Resistance, Neoplasm; Enzyme Activation; Etoposide; Humans; Melanoma; Poly(ADP-ribose) Polymerases; Signal Transduction; Tumor Cells, Cultured

2006
Valproic acid induces apoptosis, p16INK4A upregulation and sensitization to chemotherapy in human melanoma cells.
    Cancer biology & therapy, 2007, Volume: 6, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cisplatin; Etoposide; Genes, p16; Humans; Melanoma; Reverse Transcriptase Polymerase Chain Reaction; Skin Neoplasms; Up-Regulation; Valproic Acid

2007
The drug loading, cytotoxicty and tumor vascular targeting characteristics of magnetite in magnetic drug targeting.
    Biomaterials, 2007, Volume: 28, Issue:31

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Chemistry, Pharmaceutical; Diffusion; Drug Delivery Systems; Etoposide; Ferrosoferric Oxide; Melanoma; Mice; Neovascularization, Pathologic

2007
A novel mutant topoisomerase II alpha present in VP-16-resistant human melanoma cell lines has a deletion of alanine 429.
    Biochemistry, 1994, Sep-20, Volume: 33, Issue:37

    Topics: Alanine; Alleles; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Cell Line; DNA Primers; DNA Topoisomerases, Type II; Drug Resistance, Multiple; Etoposide; HeLa Cells; Humans; Melanoma; Molecular Sequence Data; Polymerase Chain Reaction; Restriction Mapping; Sequence Deletion; Tumor Cells, Cultured

1994
Mouse subrenal capsule assay chemosensitivity and DNA flow cytometry parameters of human melanoma metastases.
    Acta oncologica (Stockholm, Sweden), 1994, Volume: 33, Issue:4

    Topics: Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cisplatin; Dacarbazine; DNA, Neoplasm; Etoposide; Female; Flow Cytometry; Humans; Male; Melanoma; Mice; Middle Aged; Subrenal Capsule Assay; Vincristine

1994
Inhibition of potentially lethal and sublethal damage repair by camptothecin and etoposide in human melanoma cell lines.
    International journal of radiation biology, 1994, Volume: 66, Issue:1

    Topics: Camptothecin; Cell Death; DNA; DNA Repair; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Etoposide; Humans; Melanoma; Radiation Tolerance; Radiation-Sensitizing Agents; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1994
Characterization of an unusual mutant of human melanoma cells resistant to anticancer drugs that inhibit topoisomerase II.
    Journal of cellular physiology, 1993, Volume: 155, Issue:2

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Nucleus; DNA Topoisomerases, Type II; Drug Resistance; Etoposide; Humans; Melanoma; Membrane Glycoproteins; Mutation; Neoplasm Proteins; Reference Values; Tissue Extracts; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1993
Synergistic interactions of etoposide and interleukin-1 alpha are not due to DNA damage in human melanoma cells.
    Biochimica et biophysica acta, 1993, Jan-22, Volume: 1180, Issue:3

    Topics: Cytotoxins; DNA; DNA Damage; DNA Repair; Drug Synergism; Etoposide; Humans; Interleukin-1; Melanoma; Receptors, Interleukin-1; Tumor Cells, Cultured

1993
Acquisition of multiple copies of a mutant topoisomerase IIalpha allele by chromosome 17 aneuploidy is associated with etoposide resistance in human melanoma cell lines.
    Somatic cell and molecular genetics, 1995, Volume: 21, Issue:6

    Topics: Alleles; Aneuploidy; Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; Base Sequence; Chromosomes, Human, Pair 17; DNA Primers; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Neoplasm; Drug Resistance; Etoposide; Female; Gene Amplification; Humans; In Situ Hybridization, Fluorescence; Isoenzymes; Male; Melanoma; Molecular Sequence Data; Multigene Family; Mutation; Phenotype; Restriction Mapping; Tumor Cells, Cultured

1995
The effect of tirapazamine (SR-4233) alone or combined with chemotherapeutic agents on xenografted human tumours.
    British journal of cancer, 1996, Volume: 73, Issue:12

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cell Division; Cisplatin; Dacarbazine; Drug Screening Assays, Antitumor; Etoposide; Fluorouracil; Humans; Melanoma; Mice; Mice, Nude; Rectal Neoplasms; Tirapazamine; Transplantation, Heterologous; Triazines

1996
Chemotherapy plus local treatment in the management of intraocular retinoblastoma.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1996, Volume: 114, Issue:11

    Topics: Animals; Anterior Chamber; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Carboplatin; Combined Modality Therapy; Cryotherapy; DNA Adducts; DNA, Neoplasm; Etoposide; Eye Enucleation; Eye Neoplasms; Humans; Hyperthermia, Induced; Iodine Radioisotopes; Laser Coagulation; Melanoma; Rabbits; Retinoblastoma; Vincristine

1996
Possible role of the multidrug resistance-associated protein (MRP) in chemoresistance of human melanoma cells.
    International journal of cancer, 1997, Mar-28, Volume: 71, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Agents; ATP-Binding Cassette Transporters; Benzbromarone; Blotting, Northern; Cisplatin; Daunorubicin; Doxorubicin; Drug Resistance, Neoplasm; Enzyme Inhibitors; Ethylmaleimide; Etoposide; Female; Fluoresceins; Humans; Male; Melanoma; Middle Aged; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Probenecid; RNA, Messenger; Tumor Cells, Cultured; Uricosuric Agents; Vinblastine

1997
Genistein inhibits growth of B16 melanoma cells in vivo and in vitro and promotes differentiation in vitro.
    International journal of cancer, 1997, Sep-04, Volume: 72, Issue:5

    Topics: Animals; Antineoplastic Agents; Cell Differentiation; Cell Division; Cytochalasin B; Dose-Response Relationship, Drug; Etoposide; Female; Genistein; Growth Inhibitors; Melanoma; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Time Factors; Tumor Cells, Cultured

1997
Antitumor activity of a novel quinoline derivative, TAS-103, with inhibitory effects on topoisomerases I and II.
    Japanese journal of cancer research : Gann, 1997, Volume: 88, Issue:10

    Topics: Adenocarcinoma; Aminoquinolines; Animals; Antineoplastic Agents; Camptothecin; Cisplatin; Colonic Neoplasms; DNA; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Etoposide; Humans; Indenes; Indoles; Irinotecan; Lung Neoplasms; Male; Melanoma; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Pyridines; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1997
[The role of glutathione and glutathione-S-transferase in neoplasm drug resistance].
    Biulleten' eksperimental'noi biologii i meditsiny, 1998, Volume: 125, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Cyclophosphamide; Dacarbazine; Drug Resistance, Neoplasm; Erythrocytes; Etoposide; Female; Glutathione; Glutathione Transferase; Humans; Male; Melanoma; Ovarian Neoplasms; Propionates; Skin Neoplasms; Testicular Neoplasms

1998
Expression of DNA repair proteins hMSH2, hMSH6, hMLH1, O6-methylguanine-DNA methyltransferase and N-methylpurine-DNA glycosylase in melanoma cells with acquired drug resistance.
    International journal of cancer, 1999, Mar-01, Volume: 80, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Carrier Proteins; Cisplatin; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; Drug Resistance, Multiple; Etoposide; Humans; Melanoma; MutL Protein Homolog 1; MutS Homolog 2 Protein; N-Glycosyl Hydrolases; Neoplasm Proteins; Nitrosourea Compounds; Nuclear Proteins; O(6)-Methylguanine-DNA Methyltransferase; Organophosphorus Compounds; Promoter Regions, Genetic; Proto-Oncogene Proteins; RNA, Messenger; Transcription, Genetic; Vindesine

1999
Front-line chemotherapy with cisplatin and etoposide for patients with brain metastases from breast carcinoma, nonsmall cell lung carcinoma, or malignant melanoma. A prospective study.
    Cancer, 1999, Sep-01, Volume: 86, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cisplatin; Cranial Irradiation; Etoposide; Humans; Lung Neoplasms; Melanoma; Prospective Studies; Skin Neoplasms; Survival Analysis

1999
Alterations of DNA repair in melanoma cell lines resistant to cisplatin, fotemustine, or etoposide.
    The Journal of investigative dermatology, 2000, Volume: 114, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cisplatin; DNA Repair; DNA, Neoplasm; Drug Resistance; Etoposide; Humans; Melanoma; Microsatellite Repeats; Nitrosourea Compounds; Organophosphorus Compounds; Oxygen; Tumor Cells, Cultured; Ultraviolet Rays

2000
Modulation of DNA topoisomerase II activity and expression in melanoma cells with acquired drug resistance.
    British journal of cancer, 2000, Volume: 82, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Base Sequence; DNA Primers; DNA Topoisomerases, Type II; Drug Resistance, Neoplasm; Etoposide; Humans; Melanoma; Molecular Sequence Data; Protein Isoforms; Tumor Cells, Cultured

2000
Induction of mitochondrial permeability transition and cytochrome C release in the absence of caspase activation is insufficient for effective apoptosis in human leukemia cells.
    Blood, 2000, Mar-01, Volume: 95, Issue:5

    Topics: Animals; Antineoplastic Agents; Apoptosis; Biological Transport; Caspase Inhibitors; Caspases; Cyclosporine; Cytochrome c Group; Cytosol; Enzyme Activation; Enzyme Inhibitors; Etoposide; Fluorescence; HL-60 Cells; Humans; Intracellular Membranes; Melanoma; Mitochondria; Mitochondria, Liver; Neoplasm Proteins; Oligopeptides; Permeability; Photochemistry; Pyrimidinones; Radiation-Sensitizing Agents; Rats; Rats, Wistar; Signal Transduction; Skin Neoplasms; Staurosporine; Tumor Cells, Cultured

2000
Association of genomic imbalances with resistance to therapeutic drugs in human melanoma cell lines.
    Cytogenetics and cell genetics, 1999, Volume: 87, Issue:3-4

    Topics: Aneuploidy; Antineoplastic Agents; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 9; Cisplatin; DNA Mutational Analysis; DNA Probes; DNA Topoisomerases, Type I; Drug Resistance, Neoplasm; Etoposide; Genome, Human; Humans; Melanoma; Nitrosourea Compounds; Nucleic Acid Hybridization; Organophosphorus Compounds; Selection, Genetic; Topoisomerase I Inhibitors; Tumor Cells, Cultured; Vindesine

1999
Distinct Chk2 activation pathways are triggered by genistein and DNA-damaging agents in human melanoma cells.
    The Journal of biological chemistry, 2000, May-19, Volume: 275, Issue:20

    Topics: Caffeine; cdc25 Phosphatases; Cell Cycle; Cell Cycle Proteins; Cell Division; Checkpoint Kinase 2; Choroid Neoplasms; DNA Damage; Doxorubicin; Enzyme Activation; Etoposide; G2 Phase; Genistein; Humans; Melanoma; Protein Kinases; Protein Serine-Threonine Kinases; Tumor Cells, Cultured

2000
Identification of differentially expressed genes in human melanoma cells with acquired resistance to various antineoplastic drugs.
    International journal of cancer, 2000, Nov-15, Volume: 88, Issue:4

    Topics: Antineoplastic Agents; Base Sequence; Cloning, Molecular; DNA Primers; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Genetic Markers; Humans; Melanoma; Molecular Sequence Data; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic; Tumor Cells, Cultured

2000
Cisplatin and UV radiation induce activation of the stress-activated protein kinase p38gamma in human melanoma cells.
    Biochemical and biophysical research communications, 2000, Nov-30, Volume: 278, Issue:3

    Topics: Cisplatin; Enzyme Activation; Etoposide; Humans; Isoenzymes; Melanoma; Mitogen-Activated Protein Kinase 12; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Tumor Cells, Cultured; Ultraviolet Rays

2000
DFNA5 (ICERE-1) contributes to acquired etoposide resistance in melanoma cells.
    FEBS letters, 2001, Apr-06, Volume: 494, Issue:1-2

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carrier Proteins; Caspase 3; Caspases; Drug Resistance, Neoplasm; Enzyme Activation; Etoposide; Gene Expression; Humans; Melanoma; Receptors, Estrogen; RNA, Messenger; Transfection; Tumor Cells, Cultured

2001
Adenovirus-mediated E2F-1 gene transfer sensitizes melanoma cells to apoptosis induced by topoisomerase II inhibitors.
    Cancer research, 2002, Mar-15, Volume: 62, Issue:6

    Topics: Adenoviridae; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle Proteins; Cisplatin; Combined Modality Therapy; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cycloheximide; DNA-Binding Proteins; Doxorubicin; Drug Synergism; E2F Transcription Factors; E2F1 Transcription Factor; Enzyme Inhibitors; Etoposide; Fluorouracil; Genetic Therapy; Genetic Vectors; Humans; Male; Melanoma; Mice; Mice, Inbred BALB C; Mice, Nude; Proliferating Cell Nuclear Antigen; Purines; Roscovitine; Topoisomerase II Inhibitors; Transcription Factors; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2002
Drug resistance towards etoposide and cisplatin in human melanoma cells is associated with drug-dependent apoptosis deficiency.
    The Journal of investigative dermatology, 2002, Volume: 118, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Caspases; Cisplatin; Coumarins; Cytochrome c Group; DNA Fragmentation; Drug Resistance, Neoplasm; Enzyme Activation; Etoposide; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Peptide Fragments; Poly(ADP-ribose) Polymerases; RNA, Messenger; Tumor Cells, Cultured

2002
Neutrophil-rich Ki-1-positive anaplastic large cell lymphoma: a study by fine-needle aspiration biopsy.
    American journal of clinical pathology, 2002, Volume: 117, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Carcinoma; Cyclophosphamide; Diagnosis, Differential; Doxorubicin; Etoposide; Female; Hodgkin Disease; Humans; Infections; Ki-67 Antigen; Lymphocytes, Null; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Melanoma; Neoplasm Recurrence, Local; Neutrophils; Prednisone; Radiotherapy, Adjuvant; T-Lymphocytes; Vincristine

2002
Total-body hyperthermia with and without chemotherapy for advanced human neoplasms.
    Cancer research, 1979, Volume: 39, Issue:5

    Topics: Adult; Antineoplastic Agents; Bone Marrow; Burns; Creatine Kinase; Electroencephalography; Etoposide; Female; Humans; Hyperthermia, Induced; L-Lactate Dehydrogenase; Male; Melanoma; Melphalan; Middle Aged; Neoplasm Metastasis; Neoplasms; Peripheral Nervous System Diseases; Remission, Spontaneous; Tachycardia

1979
Evaluation of VP-16-213 in malignant lymphoma and melanoma.
    Cancer treatment reports, 1978, Volume: 62, Issue:5

    Topics: Adult; Drug Evaluation; Etoposide; Female; Hodgkin Disease; Humans; Lymphoma; Male; Melanoma; Podophyllotoxin

1978
[Enhancement of the effects of anticancer agents on B16 melanoma cells by combination with cepharanthine--I. Alkaloids].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:13

    Topics: Alkaloids; Benzylisoquinolines; Drug Synergism; Etoposide; Humans; Melanoma; Tumor Cells, Cultured; Tumor Stem Cell Assay; Vincristine; Vindesine

1992
Potentiation by phenylbisbenzimidazoles of cytotoxicity of anticancer drugs directed against topoisomerase II.
    European journal of cancer (Oxford, England : 1990), 1990, Volume: 26, Issue:5

    Topics: Acridines; Amsacrine; Animals; Antineoplastic Agents; Benzimidazoles; Bisbenzimidazole; Colonic Neoplasms; Doxorubicin; Drug Synergism; Etoposide; Fluorescent Dyes; Leukemia L1210; Lung Neoplasms; Melanoma; Mice; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Tumor Stem Cell Assay

1990
A role for the interleukin 1 receptor in the synergistic antitumor effects of human interleukin 1 alpha and etoposide against human melanoma cells.
    Cancer research, 1991, Feb-01, Volume: 51, Issue:3

    Topics: Drug Administration Schedule; Drug Synergism; Etoposide; Humans; Interleukin-1; Melanoma; Receptors, Immunologic; Receptors, Interleukin-1; Recombinant Proteins; Tumor Cells, Cultured

1991
Pharmacokinetics of very high-dose oral melphalan in cancer patients.
    American journal of clinical oncology, 1990, Volume: 13, Issue:1

    Topics: Adenocarcinoma; Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Bone Marrow Transplantation; Carmustine; Etoposide; Female; Humans; Injections, Intravenous; Lymphoma; Male; Melanoma; Melphalan; Middle Aged; Time Factors

1990
In vitro selection and characterization of a bleomycin-resistant subline of B16 melanoma.
    Cancer research, 1986, Volume: 46, Issue:4 Pt 1

    Topics: Animals; Bleomycin; Cell Line; DNA Repair; Dose-Response Relationship, Drug; Drug Resistance; Etoposide; Karyotyping; Melanoma; Mice; Tumor Stem Cell Assay

1986
Altered formation of DNA in human cells treated with inhibitors of DNA topoisomerase II (etoposide and teniposide).
    Cancer research, 1989, Nov-15, Volume: 49, Issue:22

    Topics: DNA Replication; DNA, Neoplasm; Etoposide; Humans; Kinetics; Melanoma; Podophyllotoxin; Teniposide; Thymidine; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1989
Differential cytotoxic activity of chemotherapy agents on colony-forming cells from human tumors and normal bone marrow in vitro.
    Experimental hematology, 1985, Volume: 13 Suppl 16

    Topics: Antineoplastic Agents; Bleomycin; Breast Neoplasms; Cell Survival; Cells, Cultured; Cisplatin; Doxorubicin; Etoposide; Fluorouracil; Hematopoietic Stem Cells; Humans; Lung Neoplasms; Melanoma; Neoplastic Stem Cells; Sarcoma; Stem Cells

1985
Synergistic antitumor activity of etoposide and human interleukin-1 alpha against human melanoma cells.
    Journal of the National Cancer Institute, 1989, Dec-20, Volume: 81, Issue:24

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Survival; DNA; DNA Damage; Drug Synergism; Etoposide; Humans; Interleukin-1; Melanoma; Recombinant Proteins; Tumor Cells, Cultured

1989
Summary of recent clinical experience in whole-body hyperthermia combined with chemotherapy.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1988, Volume: 107

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dacarbazine; Doxorubicin; Etoposide; Evaluation Studies as Topic; Female; Humans; Hyperthermia, Induced; Lung Neoplasms; Male; Melanoma; Vincristine; Vindesine

1988
Effective management of extremity cancers using cisplatin and etoposide in isolated limb perfusions.
    Journal of surgical oncology, 1987, Volume: 35, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Cisplatin; Etoposide; Female; Humans; Leg; Liposarcoma; Male; Melanoma; Middle Aged; Soft Tissue Neoplasms

1987