Page last updated: 2024-08-23

etoposide and Leukemia

etoposide has been researched along with Leukemia in 346 studies

Research

Studies (346)

TimeframeStudies, this research(%)All Research%
pre-199080 (23.12)18.7374
1990's122 (35.26)18.2507
2000's100 (28.90)29.6817
2010's41 (11.85)24.3611
2020's3 (0.87)2.80

Authors

AuthorsStudies
Barrows, LR; Chen, AY; LaVoie, EJ; Liu, LF; McQueen, CA; Meegalla, SK; Stevens, GJ; Yu, C1
Chen, JY; Cheng, KF; Ding, J; Meng, LH; Qin, GW; Yu, BW; Zhou, TX1
Atwal, M; Austin, CA; Bartoli, A; Lee, KC; Mariani, A; Rodriguez, R1
Dezhenkova, LG; Kalinina, AA; Kaluzhny, DN; Kubbutat, M; Luzikov, YN; Pommier, Y; Preobrazhenskaya, MN; Romanenko, VI; Schols, D; Shchekotikhin, AE; Shtil, AA; Tatarskiy, VV; Treshalin, MI; Treshalina, HM; Tsvetkov, VB; Volodina, YL1
Chen, F; Chen, Y; Lin, Y; Wang, J; Zhang, L; Zhang, Z1
Cheung, NV; Davenport, JW; Felix, CA; Gregory, BD; Li, MM; Rappaport, EF; Slater, DJ; Yu, X1
Cross, NA; Jordan-Mahy, N; Le Maitre, CL; Mahbub, AA1
Carvajal-Moreno, J; Elton, TS; Hernandez, VA; Pietrzak, M; Wang, X; Yalowich, JC1
Garten, A; Grohmann, T; Kiess, W; Penke, M; Petzold-Quinque, S; Richter, S; Schuster, S1
Aladjidi, N; Auperin, A; Couec, ML; Gandemer, V; Haouy, S; Jourdain, A; Lambliotte, A; Landman-Parker, J; Leblanc, T; Michon, J; Minard-Colin, V; Patte, C; Plat, G; Rigaud, C1
Chen, S; Chen, Y; Rao, Q; Tang, K; Tian, Z; Wang, J; Wang, JY; Wang, M; Xing, H; Yu, P1
Ahmad, SF; Attia, SM; Bakheet, SA; El Sayed, el SM; Harisa, GI; Mansour, AM1
Baradaran, B; Esfehani, A; Karami, H; Sakhinia, E; Sakhinia, M1
Byl, JA; Deweese, JE; Mercer, SL; Osheroff, N; Smith, NA1
Dong, B; Huang, H; Qu, L; Weng, H; Zhao, P; Zhou, H1
Shibayama, Y; Sugawara, M; Takada, K; Takekuma, Y; Tazawa, Y; Usukubo, I1
Hasinoff, BB; Patel, D; Wu, X; Yadav, AA; Yalowich, JC1
Beck, J; Burmeister, T; Dengler, J; Döhner, H; Domanska-Czyz, K; Dührsen, U; Fietkau, R; Gökbuget, N; Hertenstein, B; Hiddemann, W; Hoelzer, D; Horst, HA; Hüttmann, A; Kneba, M; Reichle, A; Rieder, H; Schaich, M; Schmidt-Wolf, IG; Schwartz, S; Serve, H; Spiekermann, K; Thiel, E; Viardot, A; Walewski, J1
Lehman, CE; Pierce, LC; Thys, RG; Wang, YH1
Mizutani, S; Nanya, M; Sato, M; Takagi, M; Tanimoto, K; Tozuka, M1
Aquino, V; Duerst, R; Graham, M; Moore, T; Morris, C; Morris, J; Neudorf, S; Olsson, B; Rudebeck, M; Shah, AJ1
Gerber, JM; Grunwald, MR; Induru, R; McDonnell, MH1
Chen, Z; Hu, S1
Aqaqe, N; Biechonski, S; Elad, D; Gourevich, D; Grisaru, D; Jaffa, AJ; Milyavsky, M; Olender, L; Rall, M; Raz, Y; Trakhtenbrot, L; Wiesmuller, L; Yassin, M; Zipin-Roitman, A1
Al Malki, MM; Aldoss, I; Ali, H; Aribi, A; Farol, L; Forman, SJ; Karanes, C; Khaled, S; Liu, A; Marcucci, G; Nakamura, R; O'Donnell, M; Palmer, J; Parker, P; Pawlowska, A; Pullarkat, V; Radany, E; Rosenthal, J; Sahebi, F; Salhotra, A; Sanchez, JF; Schultheiss, T; Snyder, D; Spielberger, R; Stein, A; Thomas, SH; Tsai, NC; Wong, J1
Accordino, MK; Hershman, DL; Hillyer, GC; Neugut, AI; Vasan, S; Wright, JD1
Cheung, NK; Jhanwar, SC; Kramer, K; Kushner, BH; Modak, S; Qin, LX; Yataghena, K1
Kamijo, T; Koike, K; Nakazawa, Y; Sakashita, K; Shikama, N; Shiohara, M; Tanaka, M; Yanagisawa, R1
Barretto, NN; Bennett, CA; Hemenway, CS; Winters, AC1
Chen, GQ; Duan, XF; Wen, DH; Zhao, M1
Diao, S; Liu, H; Rao, Q; Wang, J; Wang, M; Xing, H; Zhang, X1
Chen, GQ; Huang, Y; Wang, LS; Yu, Y; Yuan, TT; Zhou, CX; Zhuang, HY1
Hou, KZ; Liu, YP; Qu, XJ; Teng, YE; Yang, XH; Zhang, JD; Zhang, Y1
Chen, GQ; Cheng, JK; Duan, XF; Liu, W; Lu, Y; Zhang, B; Zhao, M; Zhao, XY1
Blasiak, J; Poplawski, T1
Abichandani, R; Barry, E; Carroll, WL; Chu, R; Cooper, T; Gaynon, P; Hijiya, N; Jeha, S; Kadota, R; Rytting, M; Shen, V; Silverman, L; Steinherz, P; Thomson, B1
Chen, ZC; Li, L; Li, QB; Xia, LH; You, Y; Zou, P1
Akutsu, M; Furukawa, Y; Izumi, T; Kano, Y; Mano, H; Miyawaki, S; Tanaka, M; Tsunoda, S; Yazawa, Y1
Grigg, AP; Hoyt, R; Ritchie, DS; Szer, J; Wirth, A1
Carlo-Stella, C; Delia, D; Drago, C; Lambertenghi Deliliers, G; Lecis, D; Manzoni, L; Onida, F; Polli, E; Scavullo, C; Seneci, P; Servida, F1
Asano, S; Funayama, K; Murai, F; Nomura, H; Shimane, M1
DeRyckere, D; Gore, L; Macy, ME1
Hara, T; Kanemura, N; Kasahara, S; Kitagawa, J; Moriwaki, H; Shimizu, M; Tsurumi, H1
Alvarnas, JC; Dagis, AC; Forman, SJ; Nademanee, AP; O'Donnell, MR; Parker, PM; Pullarkat, VA; Snyder, DS; Spielberger, RT; Stein, AS; Synold, TW; Thomas, SH; Tsirunyan, A; Wong, JY1
Andresen, S; Avalos, B; Bolwell, BJ; Copelan, E; Dean, R; Devine, S; Elder, P; Kalaycio, M; Mahindra, A; Pohlman, B; Rybicki, L; Sobecks, R; Sweetenham, J; Tench, S1
Belinka, BA; Gupta, A; Kachlany, SC; Le, A1
Bertrand, J; Bonnevialle, P; Bourogaa, E; Demur, C; Despeaux, M; Gallay, N; Joly, S; Louache, F; Maguer-Satta, V; Payrastre, B; Racaud-Sultan, C; Vergnolle, N1
Shigematsu, A1
Delalande, F; Domon-Dell, C; Duluc, I; Freund, JN; Gross, I; Martin, E; Renouf, B; Saandi, T; Soret, C; Vanier, M1
Gaynon, P; Lindsay, H1
Anderson, DJ; Belmont, LD; Bouillet, P; Campbell, KJ; Cory, S; Fairlie, WD; Glaser, SP; Huang, DC; Khaw, SL; Lee, EF; Ludlam, MJ; Mérino, D; Phipson, B; Robati, M; Roberts, AW; Vandenberg, CJ; Wong, C; Yue, P1
Braess, J; Holdenrieder, S; Kolligs, FT; Manukyan, D; Stieber, P1
Jasek, E; Jasinska, M; Jurkowska, H; Lis, GJ; Litwin, JA1
Matsumura, K; Sugawara, M; Takekuma, Y; Tazawa, Y1
Austin, CA; Cowell, IG1
Ahmed, AB; Bruserud, O; Hatfield, KJ; Kittang, AO; Reikvam, H; Sjo, M; Tvedt, TH1
Mizutani, S; Porter, AC; Sato, M; Shimizu, T; Takagi, M; Tamaichi, H1
Braylan, R; Chen, SF; Fieniewicz, KJ; Gomez, SP; Kahn, S; Leather, H; Lynch, J; Mainwaring, MG; May, WS; Moreb, J; Reddy, V; Rimsza, LM; Rowe, TC; Weeks, FW; Wingard, JR1
Joel, SP; Liu, WM; Oakley, PR1
Panetta, JC; Pui, CH; Relling, MV; Wilkinson, M1
Balduzzi, A; Biondi, A; Bonanomi, S; Dassi, M; Gaipa, G; Perseghin, P; Rovelli, A; Uderzo, C1
Grigg, AP; Ritchie, DS; Roberts, AW; Shuttleworth, P; Szer, J1
Allan, WP; Kroll, DJ; Kurz, EU; Leader, KB; Sampey, BP; Wilson, SE; Yalowich, JC1
Gore, SD; Malek, SN1
Grzanka, A; Grzanka, D1
Bayle, C; Bernheim, A; Cayuela, JM; Chompret, A; de Vathaire, F; Hill, C; Lacour, B; Le Deley, MC; Leblanc, T; Raquin, MA; Shamsaldin, A; Sommelet, D; Vassal, G1
Austin, RC; Baumeister, P; Kaufman, RJ; Lee, AS; Mao, C; Reddy, RK1
Abe, A; Emi, N; Kanbe, E; Kawabe, T; Saito, H; Towatari, M1
Joel, SP; Liu, WM1
Kato, K; Kojima, S; Kudo, K; Matsuyama, T; Nakamoto, C; Nakamura, Y; Yoshimi, A1
Diehl, V; Dörken, B; Dühmke, E; Franklin, J; Hasenclever, D; Herrmann, R; Lathan, B; Loeffler, M; Müller-Hermelink, HK; Paulus, U; Pfreundschuh, M; Tesch, H1
Lan, Y; Shen, BF; Yang, PD; Zhang, XM1
Rikiishi, H; Sato, K; Shinohara, F; Suzuki, M; Takada, H; Taniguchi, T1
Blanco, JG; Edick, MJ; Relling, MV1
Berger, SA; Zhang, Y1
Wang, LL; Xu, CG; Zhang, MH1
Boehden, GS; Marschalek, R; Restle, A; Stocking, C; Wiesmüller, L1
Agazzi, A; Bertolini, F; Calabrese, L; Cinieri, S; Cocquio, A; Goldhirsch, A; Laszlo, D; Martinelli, G; Pruneri, G; Rabascio, C1
Astruc, J; Barret, JM; Chansard, N; Créancier, L; Duchier, C; Hill, BT; Kruczynski, A; Menon, Y; Van Hille, B1
Campiani, G; Greene, LM; Lawler, M; Ledwidge, S; Mc Gee, MM; Nacci, V; Williams, DC; Zisterer, DM1
Markman, M1
Avalos, B; Bechtel, T; Copelan, E; Elder, P; Ezzone, S; Farag, S; Hoshaw-Woodard, S; Lemeshow, S; Lin, T; Marcucci, G; Penza, S; Scholl, MD1
Abonour, R; Einhorn, LH; Houck, W; Vance, G1
Debatin, KM; Karawajew, L; Liu, J; Meyer, LH; Mohr, A; Stahnke, K1
Clotagatide, A; Denoyer, D; Dubois, F; Frere, D; Jeune, NL; Perek, N; Sabido, O1
Chang, JS; Choi, YB; Kim, CG; Kim, JW; Kim, YH; Ko, J; Kuroki, T; Lee, YH; Min, DS; Na, DS; Ohba, M; Shin, SY1
Billi, AM; Bortul, R; Cocco, L; Conte, R; Manzoli, L; Martelli, AM; Tabellini, G; Tazzari, PL1
Cataldi, A; Comani, S; Di Pietro, R; Rapino, M; Sabatini, N; Sancilio, S1
Ikarashi, Y; Imai, C; Kakihara, T; Tanaka, A; Uchiyama, M; Watanabe, A1
Chen, Q; Chen, Y; Hou, Y; Li, C; Li, X; Wang, B; Zhang, Z; Zou, P1
Beauchemin, M; Bergeron, S; Bertrand, R1
Bauer, KS; Garimella, TS; Karp, JE; Ross, DD; Tan, M; Wu, S1
Arai, A; Jin, ZH; Kurosu, T; Miura, O; Yamaguchi, M1
Magnusson, KE; Navakauskiene, R; Savickiene, J; Treigyte, G1
Seiter, K1
Hartmann, O; Le Deley, MC; Leblanc, T; Shamsaldin, A; Taïbi, A; Vassal, G1
Aksu, S; Güven, GS; Koçak, T; Ozçakar, L1
Billi, AM; Bortul, R; Cappellini, A; Conte, R; Grafone, T; Mantovani, I; Martelli, AM; Martinelli, G; Tabellini, G; Tazzari, PL1
Abella, E; Brunet, S; del Potro, E; Esteve, J; Oriol, A; Ribera, JM1
Asano, T; Fukunaga, Y; Kleinerman, ES; Zhou, Z; Zwelling, LA1
Barbier, M; Bignon, J; Boutonnat, J; Colle, PE; Faussat, AM; Marie, JP; Ronot, X; Thierry, J; Wdzieczak-Bakala, J1
Gallagher, EP; Moneypenny, CG; Shao, J; Song, Y1
Bestwick, CS; Milne, L1
Barnett, MJ; Forrest, DL; Hogge, DE; Johny, A; Lavoie, JC; Le, A; Nantel, SH; Nevill, TJ; Nitta, JY; Shepherd, JD; Smith, CA; Song, KW; Sutherland, HJ; Toze, CL1
Chen, GQ; Gu, ZM; Huang, Y; Li, D; Sims, PJ; Wiedmer, T; Xu, HZ; Zhao, KW; Zhao, Q; Zhou, CX1
Chen, SM; Dong, JX; Liu, YF; Sun, H; Zhang, QT1
Akutsu, M; Furukawa, Y; Izumi, T; Kano, Y; Kobayashi, H; Mano, H; Tsunoda, S1
Aoun, M; Beguin, H; Georgala, A; Husson, M; Meuleman, N; Nolard, N; Vekemans, M1
Cheng, Y; Liu, N; Qi, J; Tan, Y; Xiong, D; Yang, C; Zhou, Y; Zhu, Z1
Kantidze, OL; Razin, SV1
Akutsu, M; Furukawa, Y; Izumi, T; Kano, Y; Kirito, K; Mano, H; Matsuo, Y; Odgerel, T; Sato, Y; Tsunoda, S; Vu, HA1
Kersey, J; Weigel, B; Yao, Q1
Chen, H; Han, W; Huang, XJ; Liu, DH; Liu, KY; Xu, LP1
Barberi, W; Foa, R; Giona, F; Malandruccolo, L; Mandelli, F; Martino, P; Moleti, ML; Palumbo, G; Paoloni, F; Pescarmona, E; Testi, AM1
Barjesteh van Waalwijk van Doorn-Khosrovani, S; Godschalk, RW; Janssen, J; Maas, LM; Nijhuis, JG; van Schooten, FJ1
Havredaki, M; Scorilas, A; Thomadaki, H; Tsiapalis, CM1
Bogni, A; Cheng, C; Dolan, ME; Fan, Y; Hartford, C; Liu, W; Neale, G; Pounds, S; Pui, CH; Raimondi, SC; Relling, MV; Treviño, L; Yang, W1
Fujioka, K; Funabiki, T; Goto, H; Goto, S; Hanzawa, N; Ikuta, K; Izaki, S; Kai, S; Matsuda, M; Okuda, K; Sasaki, H; Sekiguchi, H; Sumita, H; Takahashi, H; Watanabe, Y; Yokota, S1
Böttger, S; Jerszyk, E; Low, B; Walker, C1
Hsu, PC; Hung, HC; Liao, YF; Liu, CC; Liu, GY; Tsay, GJ1
Dahl, GV; Look, AT; Mauer, AM; Rivera, G1
Bowman, WP; Dahl, GV; Evans, WE; Kalwinsky, D; Look, AT; Rivera, G1
Gahrton, G1
Barlogie, B; Cabanillas, F; Freireich, EJ; Keating, M1
Brunner, KW; Cavalli, F; Goldhirsch, A; Joss, R; Ryssel, HJ; Sonntag, RW1
Kennedy, BJ; Raghavan, D; Vogelzang, NJ1
Płuzańska, A; Robak, T1
Hattori, K; Ito, K; Kobayashi, S; Nakamura, S; Nakanishi, J; Ohtake, S; Yoshida, T1
Etcubanas, E; Evans, W; Hayes, FA; Hutson, P; Sinkule, JA1
Arakawa, S; Esumi, N; Imashuku, S1
Crom, WR; Dow, L; Evans, WE; Look, AT; Rivera, G; Sinkule, JA1
Cavalli, F; Sauter, C; Varini, M1
Allan, WP; Fields, AP; Murray, NR; Ritke, MK; Yalowich, JC1
Csoka, K; Larsson, R; Liliemark, J; Nygren, P1
Abe, T; Fujii, H; Kuzuyama, Y; Nakagawa, H; Sakabe, H; Sonoda, Y1
Aarbakke, J; Endresen, PC; Prytz, PS1
Ichikawa, Y; Kawada, H; Mukaiyama, T; Ogawa, Y; Watanabe, S1
Gastineau, DA; Hoagland, HC; Letendre, L; Noel, P; Solberg, LA; Tefferi, A1
Beere, HM; Chapman, RS; Chresta, CM; Dive, C; Heer, S; Herberg, AA; Hickman, JA; Whetton, AD1
Dubrez, L; Genne, P; Goldwasser, F; Pommier, Y; Solary, E1
Bernstein, E; Brodsky, I; Bulova, S; Crilley, P; Marks, DI; Mullaney, R; Resnick, K; Styler, MJ; Topolsky, D1
Beyer, J; Bokemeyer, C; Kuczyk, MA; Schmoll, HJ; Siegert, W1
Breeden, ES; Einhorn, LH; Loehrer, PJ; Nichols, CR; Williams, SD1
Collins, R; Fay, J; Herzig, G; Pineiro, L1
Amylon, MD; Blume, KG; Chao, NJ; Kusnierz-Glaz, C; Long, GD; Negrin, RS1
Felix, CA; Hosler, MR; Lange, BJ; Masterson, M; Wilson, AE; Winick, NJ1
Abe, T; Kawano, Y; Makimoto, A; Nakagawa, R; Okamoto, Y; Saito, S; Sato, J; Shimizu, T; Suzue, T; Takaue, Y1
Bokemeyer, C; Schmoll, HJ1
Ballester, OF; Cooper, BW; Creger, RJ; Elfenbein, GJ; Fields, KK; Hiemenz, JH; Janssen, WE; Lazarus, HM; Perkins, JB; Zorsky, PE1
Hashimoto, S; Hasuike, T; Hirai, M; Hirai, N; Kou, KR; Ohta, K; Ohta, T; Takekawa, K; Tanaka, K; Yamane, T1
Berdel, WE; Vogler, WR1
Allan, WP; Dive, C; Heer, S; Lazo, JS; Ritke, MK; Rusnak, JM; Yalowich, JC1
Biersack, H; Boege, F; Meyer, P1
Ellis, AL; Nowak, B; Plunkett, W; Zwelling, LA1
Benson, E; Bishop, J; Bradstock, K; Matthews, J; Page, F1
Allan, WP; Fattman, C; Gunduz, NN; Ritke, MK; Yalowich, JC1
Muggia, FM1
Kobayashi, K; Ratain, MJ2
Andersson, BS; Dimopoulos, M; Gajewski, J; Giralt, SA; Khouri, I; LeMaistre, CF; Mehra, R; Przepiorka, D; Van Besien, K; Vriesendorp, HM1
Bowman, WP; Dubowy, R; Land, V; Parmley, RT; Pollock, BH; Pratt, C; Sadowitz, PD; Souid, A; Vats, T; Weinstein, H1
Bastie, JN; Baumelou, E; Casassus, P; Coloma, F; Delmas-Marsalet, B; Delmer, A; Faussat Suberville, AM; Leroux, G; Marie, JP; Rio, B1
Fujioka, K; Funabiki, T; Ikuta, K; Kai, S; Kajigaya, Y; Matsuyama, S; Sakai, H; Sekiguchi, H; Sumita, H; Takahashi, H1
Davidson, A; Lewis, I; Pearson, AD; Pinkerton, CR; Stevens, MC1
Benz, G; Gmür, J; Gubler, J1
Evans, WE; McLeod, HL1
Nomura, T; Ogata, K1
Gantchev, T; Kagan, V; Stoyanovsky, D; Yalowich, J1
Cahill, R; Deeg, HJ; Gadner, H; Ortlieb, M; Peters, C; Spitzer, TR; Tefft, MC; Torrisi, J; Urban, C1
Bokemeyer, C; Poliwoda, H; Schmoll, HJ1
Aricò, M; Broadbent, V; Gadner, H; Grois, N; Jacobson, A; Komp, D; Ladisch, S; Nicholson, HS1
Ritke, MK; Yalowich, JC1
Altschuler, E; Bales, E; Ellis, AL; Hinds, M; Mayes, J; Soares, L; Zipf, TF; Zwelling, LA1
Tutschka, PJ1
Fisher, LM; Patel, S1
Carter, C; Hodges, S; Lee, EJ; Reck, K; Schiffer, CA1
Appelbaum, FR; Blume, KG; Forman, SJ; Henslee-Downey, JP; Kopecky, KJ; LeMaistre, CF; Stiff, PJ1
Ikeda, H; Inoue, T; Masaoka, T; Murayama, S; Ohtani, M; Shibata, H; Song, C; Tang, JT; Teshima, T; Yamazaki, H1
Brauner, R; Devergie, A; Fischer, A; Fontoura, M; Gluckman, E; Griscelli, C; Michon, J; Prevot-Saucet, C; Souberbielle, JC; Zucker, JM1
Anderson, JR; Armitage, JO; Bierman, P; Bishop, MR; Cowles, MK; Kessinger, A; Martin-Algarra, S; Reed, E; Tarantolo, S; Vose, JM1
Elonen, E; Jokipii, A; Lautenschlager, I; Lyytikäinen, O; Ruutu, P; Tiittanen, L1
Asaka, M; Hara, N; Kawamura, K; Kurosawa, M; Okabe, M; Sakurada, K; Suzuki, S1
Broeker, PL; Pomykala, H; Rowley, JD; Super, HG; Tanabe, S; Thirman, MJ; Yonebayashi, Y; Zeleznik-Le, N1
Andrews, F; Bolwell, B; Collins, R; Fay, J; LeFever, A; Levitt, D; List, A; Nemunaitis, J; Pallansch, P; Resta, D; Rosenfeld, CS; Schuster, MW; Taylor, R1
Bertrand, R; Dubrez, L; Eymin, B; Pommier, Y; Solary, E1
Ager, S; Baglin, TP; Bass, G; Mahendra, P; Marcus, RE; Richards, EM1
Akutsu, M; Kano, Y; Suzuki, K; Tsunoda, S1
Chen, X; Huang, G; Wang, W1
Allan, WP; Fattman, CL; Hasinoff, BB; Yalowich, JC1
Frankfurt, OS; Robb, JA; Sugarbaker, EV; Villa, L1
Doi, T; Kobayashi, D; Koike, K; Kougo, Y; Matsunaga, T; Muramatsu, H; Niitsu, Y; Sakamaki, S; Sato, T; Watanabe, N1
Higa, T; Kasai, M; Kiyama, Y; Kobayashi, N; Masauzi, N; Naohara, T; Ogasawara, M; Ohizumi, H; Saito, M; Suzuki, G1
Fraser, MJ; Ireland, CM; Papaioannou, A; Pittman, SM; Tynan, SJ1
Avalos, BR; Bechtel, TP; Belt, PS; Copelan, EA; Elder, PJ; Ezzone, SA; Hehmeyer, DM; Penza, SL; Scholl, MD1
Chen, CL; Fuscoe, JC; Liu, Q; Mahmoud, HH; Pui, CH; Relling, MV1
Allouche, M; Dubrez, L; Eymin, B; Solary, E1
Gantchev, TG; Hunting, DJ1
Brodsky, AL; Melero, MJ; Minissale, CJ; Sánchez Avalos, JC1
Asaka, M; Hashino, S; Imamura, M; Kasai, M; Kobayashi, S; Sakurada, K; Tanaka, J1
Forman, SJ; Margolin, KA; Wright, C1
Fales, I; Hrubá, A; Kavan, P; Kobylka, P; Matĕjcková, S; Skala, JP; Starý, J; Vodvárková, S1
Davey, MW; Davey, RA; Harvie, RM1
Gupta, E; Ibrahim, N; Li, XG; Mendoza, J; Pantazis, P; Patel, M; Rubin, EH; Saleem, A1
Catchpoole, DR; Sleiman, RJ; Stewart, BW1
Amarante-Mendes, GP; Bhalla, K; Green, DR; Huang, Y; Liu, L; Naekyung Kim, C; Perkins, CL1
Carriço, MK; Coelho, AM; Klumb, CE; Maia, RC; Noronha, H; Ruimanek, VM; Vasconcelos, FC1
Austin, CA; Frank, AJ; Padget, K; Tilby, MJ; Willmore, E1
Catovsky, D; Killick, S; Matutes, E; Swansbury, J1
Azuma, T; Deguchi, S; Hara, M; Harada, M; Kojima, K; Nakao, S; Narumi, H; Omoto, E; Shinagawa, K; Sunami, K; Takamatsu, H1
Davey, MW; Davey, RA; Grech, KV1
Bajorin, D; Cheung, NK; Heller, G; Kramer, K; Kushner, BH; Meyers, PA; Polyak, T; Wollner, N1
Abboudi, Z; Abrahamson, G; Apperley, JF; Chilcott, S; Craddock, C; Davis, J; Kanfer, EJ; MacDonald, C; Macdonald, D; McGuigan, D; Newlands, ES; Olavarria, E; Philpott, N; Rustin, GJ; Samson, D; Seckl, MJ; Sekhar, M; Stern, S1
Chanock, SJ; Hiraoka, W; Nieves-Neira, W; Pommier, Y; Vazquez, N1
Bruntsch, U; Diehl, V; Dölken, G; Engert, A; Franklin, J; Hasenclever, D; Koch, P; Lathan, B; Loeffler, M; Müller, U; Pfreundschuh, M; Rüffer, U; Schalk, KP; Schmitz, N; Schwieder, G; Sieber, M; Tesch, H; Tirier, C; Worst, P; Wulf, G1
Auner, H; Emmerich, B; Hass, R; Meinhardt, G; Roth, J; Totok, G1
Anderson, JR; Arthur, D; Catalano, PJ; Freidlin, B; Heyn, R; Khayat, A; Krailo, M; Land, VJ; Miser, J; Rubinstein, L; Shuster, J; Smith, MA; Vena, D1
Camera, A; Catalano, L; Picardi, M; Rotoli, B; Selleri, C1
Alessandrino, EP; Bernasconi, C; Bernasconi, P; Bonfichi, M; Caldera, D; Colombo, A; Malcovati, L; Martinelli, G; Pagnucco, G; Salvaneschi, L1
Droin, N; Eymin, B; Haugg, M; Munsch, B; Solary, E; Sordet, O; Van de Craen, M; Vandenabeele, P1
Boos, J; Gumbinger, HG; Hempel, G; Jürgens, H; Wagner, A1
Andoh, T1
Albertioni, F; Eriksson, S; Keszler, G; Sasvári-Székely, M; Spasokoukotskaja, T; Staub, M1
Arber, DA; Bhatia, R; Bhatia, S; Forman, SJ; Fung, H; Kashyap, A; Krishnan, A; Molina, A; Nademanee, A; Niland, JC; O'Donnell, MR; Parker, PA; Slovak, ML; Sniecinski, I; Snyder, DS; Spielberger, R; Stein, A1
Engel, R; Gump, JL; Sullivan, DM; Valkov, NI1
Abboud, CN; Constine, LS; DiPersio, JF; Duerst, RE; Horan, JT; Liesveld, JL; Passarell, JA; Raubertas, RF; Senf, ES; Zwetsch, LM1
Carton, J; Hannun, YA; Meredith, F; Perry, DK; Shah, AK; Uhlinger, DJ1
Cotter, FE; Fennell, DA1
Capranico, G; D'Incalci, M; Giaccone, G1
Johnson, LM; Lorico, A; Murren, JR; Rappa, G; Sartorelli, AC1
Esche, H; Opalka, B; Parssanedjad, K; Pützer, BM; Stiewe, T1
Bhalla, K; Nguyen, D; Perkins, C; Ramadevi, N; Wen, J; Worthington, E1
Laroche-Clary, A; Larrue, A; Robert, J1
Bajwa, RP; Reid, MM; Skinner, R; Wariyar, UK; Windebank, KP1
Kancherla, R; Nair, JS; Seiter, K; Traganos, F; Tse-Dinh, YC1
Kim, S; Kim, SH; Kim, WK; Lee, JH; Lee, JS; Lee, KH; Seol, M1
Hedley, DW; Pham, NA1
Bertrand, R; Bichat, F; Droin, N; Hammann, A; Rébé, C; Solary, E1
Ancín, I; Berlanga, JJ; Ferrá, C; Gallardo, D; González, JR; Grañena, A; Marín, D; Muñoz, J; Peris, J; Sarrá, J1
Bruey, JM; Corcos, L; Garrido, C; Leroy, I; Lizard, G; Miguet, C; Plenchette, S; Rébé, C; Solary, E; Sordet, O1
Antin, J; Ault, K; Elias, A; Ibrahim, J; Khurshid, A; Mauch, P; Wheeler, C1
Bohgaki, T; Kohno, M; Kondo, M; Mukai, M; Notoya, A1
Jia, L; Kelsey, SM; Liu, KZ; Mantsch, HH; Newland, AC1
Baker, RK; Irons, RD; Kroll, DJ; Kurz, EU; Pyatt, DW1
Alnemri, ES; Fernandes-Alnemri, T; Jia, L; Kelsey, SM; Newland, AC; Patwari, Y; Srinivasula, SM1
Grzanka, A1
Arcese, W; Cerretti, R; De Felice, L; Donato, V; Fenu, S; Guglielmi, C; Iori, A; Laurenti, L; Mengarelli, A; Micozzi, A; Romano, A; Torromeo, C1
Albertioni, F; Fredriksson, E; Liliemark, E; Ljungquist, S; Polischouk, A; Soderhall, S1
Al-Jefri, A; Al-Mahr, M; Ayas, M; Belgaumi, A; Leung, W; Solh, H1
Fraser, AV; Wallace, HM; Woster, PM1
Wiernik, PH1
Bunn, PA; Ihde, DC; Radice, PA1
Amiel, JL; Berger, R; Rouesse, J1
Henney, JE; Muggia, FM; Rozencweig, M; Von Hoff, DD1
Crooke, ST; Issell, BF1
Crooke, ST; Gutierrez, ML1
Illiger, HJ; Labedzki, L1
Dubovsky, D; Jacobs, P; Kernoff, L1
Biersack, H; Boege, F; Gieseler, F; Meyer, P1
Lorico, A; Rappa, G; Sartorelli, AC1
Ashihara, E; Fujita, N; Goto, H; Inaba, T; Ito, K; Murakami, S; Okawa, K; Oku, N; Shimazaki, C; Tsuji, H1
Dan, K; Gomi, S; Ito, T; Nomura, T; Ogata, K; Ohki, I; Tanabe, Y; Yamada, T1
Aihara, M; Blume, KG; Chao, NJ; Kühl, JS; Sikic, BI1
Fay, JW; Harden, EA; Herzig, GP; Herzig, RH; Heye, MM; Meagher, RC; Montes, VM; Stevens, DA1
Copelan, EA1
Blume, KG; Forman, SJ1
Andersson, BS; Brunner, LJ; Huan, SD; LeMaistre, CF; Spencer, V; Spinolo, JA; Spitzer, G; Wallerstein, RO; Woo, SY; Yau, JC1
Appelbaum, FR; Bensinger, WI; Buckner, CD; Clift, RA; Deeg, HJ; Petersen, FB; Sanders, JE; Storb, R; Sullivan, KM; Witherspoon, RP1
Busch, FW; Ehninger, G; Hiddemann, W; Jaschonek, K; Proksch, B; Schleyer, E; Schmidt, H; Schuler, U; Wanner, T1
Nakamura, T; Ueda, T1
Altschuler, E; Chan, D; Hinds, M; Mayes, J; Zwelling, LA1
Aihara, M; Aihara, Y; Blume, KG; Chao, NJ; Schmidt-Wolf, G; Schmidt-Wolf, I; Sikic, BI1
Rybka, WB1
Hattori, M; Kuga, T; Makishima, M; Sampi, K1
Bierman, PJ; Dennison, JD; Gordon, BG; Klassen, L; Kumar, PP; McGuire, TR; Reed, EC; Sanger, WG; Vaughan, WP; Warkentin, PI1
Benítez, J; Calabuig, T; Outeiriño, J; Pérez Sáenz, MA; Prieto, E; Rodríguez, C; Sánchez Fayos, J1
Emminger, W; Emminger-Schmidmeier, W; Gadner, H; Peters, C1
Butturini, A; Gale, RP; Reizenstein, P1
Diedrich, H; Freund, M; LeBlanc, S; Link, H; Poliwoda, H; Wilke, HJ1
Brashear, T; Fay, J; Miller, G; Stone, M1
Larsson, R; Nygren, P1
Anasetti, C; Appelbaum, FR; Beatty, P; Doney, K; Martin, P; Pepe, M; Stewart, P; Storb, R; Sullivan, KM; Witherspoon, R1
Aihara, M; Blume, KG; Chao, NJ; Sikic, BI1
Broustet, A; Cony, P; Duclos, F; Marit, G; Puntous, M; Reiffers, J1
Bolwell, BJ; Brown, RA; Frei-Lahr, D; Hande, KR; Harden, EA; Herzig, GP; Herzig, RH; Lowder, JN; Pineiro, L; Wolff, SN1
Gulati, SC; Lemoli, RM1
Danno, K; Hamato, N; Kobashi, Y; Ohno, S; Ohno, Y; Ohta, M; Tomii, K; Yamamoto, M; Yokoo, T1
Lampkin, BC1
Colvin, OM; Santos, GW1
Dahl, GV; Jackson, CW; Kalwinsky, DK; Look, AT; Mirro, J1
Castleberry, R; Hakami, N; Harris, R; Krischer, J; Look, AT; Ravindranath, Y; Steuber, PC; Vietti, TJ1
DeVita, VT; Glatstein, E; Ihde, DC; Jaffe, ES; Longo, DL; Young, RC1
Douay, L1
Clemens, MR; Ehninger, G; Gey, KF; Ladner, C1
Anas, N; Cairo, MS; Sender, L; Siegel, S1
Bauer, H; Fehrentz, D; Hunstein, W; Keilholz, U; Körbling, M1
Bregni, M; Gianni, AM; Siena, S; Tarella, C1
Hamada, H; Ishida, Y; Minato, K; Ohtsu, T; Shimoyama, M; Sugimoto, Y; Tobinai, K; Tsuruo, T1
Furukawa, Y; Im, T; Inoue, T; Kishida, T; Park, K; Sasaki, A; Tatsumi, N; Yamane, T1
Jones, RJ; Santos, GW1
Kumano, N; Motomiya, M; Oizumi, K; Saijo, Y; Satoh, K; Tokue, Y1
Bernasconi, C1
Cahill, R; Cottler-Fox, M; Deeg, HJ; Greenspan, A; Lynch, M; Spitzer, TR; Torrisi, J1
Cassileth, PA; Gale, RP; Stadtmauer, EA1
McVie, G; Muggia, FM1
Bitran, JD; Hoffman, PC; Kaminer, LS; Larson, RA; Le Beau, MM; Purl, S; Ratain, MJ; Skosey, C; Vardiman, JW; Wade, J1
Edwards, CM; Glisson, BS; King, CK; Ross, WE; Smallwood-Kentro, S1
Andersson, BS; Bakic, M; Beran, M; Chan, D; Estey, E; Ricketts, L; Silberman, L; Zwelling, LA1
Beck, WT; Cirtain, MC; Danks, MK; Schmidt, CA; Suttle, DP1
Alonso, MT; Leyland-Jones, B; Marsoni, S; O'Dwyer, PJ; Wittes, RE1
Hansen, HH; Hansen, M; Osterlind, K; Pedersen, AG; Pedersen-Bjergaard, J; Philip, P1
White, JC; Wright, SE1
Akaboshi, M; Kanamaru, A; Kobayashi, Y; Kohsaki, M; Miyawaki, S; Mizoguchi, H; Nagai, K; Sawamura, M; Takaku, F; Tsuchiya, J1
Brix, F; Gassmann, W; Heit, W; Hertenstein, B; Holthuis, JJ; Johannson, W; Rister, M; Schaub, J; Schmitz, N; Suttorp, M1
Araki, Y; Makino, S; Seita, M; Tamura, K1
Hervé, P; Tamayo, E1
Behm, F; Dahl, GV; Kalwinsky, D; Mason, C; Mirro, J; Schell, M1
Hiddemann, W; Kreutzmann, H; Maschmeyer, G; Wendt, F1
Gratwohl, A; Häfliger, B; Speck, B; Tichelli, A; Würsch, A1
Amadori, S; Avvisati, G; Mandelli, F; Meloni, G; Petti, MC; Tafuri, A1
Ibrahim, NK; Khouri, FP; Salem, PA1
Hiyoshi, M; Kawarabayashi, K; Kishida, T; Kojima, K; Sagawa, H; Sannomiya, Y; Sasaki, A; Yamane, T; Yokomatsu, Y; Yoshikawa, T1
Bishop, JF; Cobcroft, R; Dodds, A; Joshua, DE; Kronenberg, H; Lowenthal, RM; Manoharan, A; Whiteside, MG; Wolf, M1
Dalton, RJ; Gerstner, JB; Letendre, L; Levitt, R; Mailliard, JA; Pierre, RV; Therneau, TM1
Horiuchi, A; Kanamaru, A; Kawagoe, H; Kitani, T; Kohsaki, M; Masaoka, T; Nagai, K; Shibata, H; Tagawa, S; Tsubaki, K1
Carella, AM; Cerri, R; Congiu, A; Damasio, E; Gaozza, E; Giordano, D; Martinengo, M; Nati, S; Risso, M; Santini, G1
Appelbaum, FR; Buckner, CD1
Lampkin, BC; Wong, KY1
Creger, RJ; Diaz, D; Lazarus, HM1
Andreeff, M; Ciobanu, N; Paietta, E; Papenhausen, P; Wiernik, PH1
Dicke, KA; Horwitz, LJ; Jagannath, S; Keating, M; McCredie, KB; Spitzer, G; Vellekoop, L; Zander, AR1
Blume, KG; Doroshow, JH; Fahey, JL; Forman, SJ; Krance, RA; Metter, GE; Nademanee, AP; O'Donnell, MR; Schmidt, GM; Snyder, DS1
Amos, D; Appelbaum, FR; Goldberg, RS; Livingston, RB; Mortimer, J; Tallman, MS; Thomas, ED; Weiden, PL1
Ando, Y1
Abrams, RA; Anderson, T; Hansen, RM; Hanson, G1
Ogawa, M1
Andersson, BS; Beran, M; McCredie, KB; Odaimi, M1
Castro-Malaspina, H; Gulati, SC; Kushner, BH; Kwon, JH1
Anderson, NR; Arkin, CF; Bern, MM; Corkery, JC; Huberman, MS; Lokich, JJ; Paul, SD; Phillips, DF; Sonneborn, HA; Wallach, SR1
Abe, T; Kariyone, S; Maekawa, I; Maekawa, T; Miura, A; Miura, Y; Moriyama, Y; Shibata, A; Wakui, A; Yoshida, Y1
Hinemann, V; Hoagland, HC; Kovach, JS; Letendre, L1
Carella, AM; Cerri, R; Congiu, A; Frassoni, F; Giordano, D; Marmont, A; Martinengo, M; Nati, S; Risso, M; Santini, G1
Bassez, T; David, JC; Maniey, D; Rusquet, R1
Jacobs, P1
Kimura, K; Yamada, K; Yoshida, T1
Arakawa, S; Esumi, N; Imashuku, S; Todo, S1
Hines, LH; Rathmell, JP; White, JC1

Reviews

34 review(s) available for etoposide and Leukemia

ArticleYear
Cutaneous manifestations in leukemia patients.
    Seminars in oncology, 2016, Volume: 43, Issue:3

    Topics: Adenine Nucleotides; Antineoplastic Agents; Arabinonucleosides; Clofarabine; Cytarabine; Dermatomycoses; Etoposide; Humans; Leukemia; Mastocytosis; Niacinamide; Paraneoplastic Syndromes; Phenylurea Compounds; Skin Diseases, Bacterial; Skin Neoplasms; Sorafenib

2016
[Significance of intensified conditioning regimen for allogeneic hematopoietic stem cell transplantation for treatment of acute leukemias].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2011, Volume: 52, Issue:8

    Topics: Acute Disease; Cyclophosphamide; Cytarabine; Etoposide; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Melphalan; Recurrence; Risk; Transplantation Conditioning; Transplantation, Homologous; Whole-Body Irradiation

2011
High-dose etoposide in allogeneic stem cell transplantation.
    Cancer chemotherapy and pharmacology, 2012, Volume: 70, Issue:6

    Topics: Adenine Nucleotides; Anthracyclines; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Busulfan; Carboplatin; Carmustine; Clinical Trials as Topic; Clofarabine; Cyclophosphamide; Dose Fractionation, Radiation; Drug Administration Schedule; Etoposide; Humans; Ifosfamide; Leukemia; Leukemia, Myeloid, Acute; Lomustine; Mucositis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiotherapy, Adjuvant; Severity of Illness Index; Stem Cell Transplantation; Transplantation Conditioning; Transplantation, Homologous; Whole-Body Irradiation

2012
Experience with platinum-based and high-dose chemotherapy in patients with gestational trophoblastic disease: possible implications for future management.
    Journal of cancer research and clinical oncology, 2004, Volume: 130, Issue:7

    Topics: Adult; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Leukemia; Pregnancy; Uterine Neoplasms

2004
Toxicity of the topoisomerase II inhibitors.
    Expert opinion on drug safety, 2005, Volume: 4, Issue:2

    Topics: Antineoplastic Agents; Cardiovascular Diseases; Daunorubicin; Doxorubicin; Enzyme Inhibitors; Epirubicin; Etoposide; Humans; Idarubicin; Leukemia; Middle Aged; Mitoxantrone; Mucositis; Podophyllotoxin; Teniposide; Topoisomerase II Inhibitors; Vascular Diseases

2005
Treatment of acute leukemia--advances in chemotherapy, immunotherapy, and bone marrow transplantation.
    Advances in cancer research, 1983, Volume: 40

    Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Age Factors; Aminoacridines; Amsacrine; Anthraquinones; Antibodies, Monoclonal; Azacitidine; Bone Marrow Transplantation; Child; Child, Preschool; Drug Administration Schedule; Etoposide; Humans; Ifosfamide; Immunotherapy; Infant; Interferons; Leukemia; Leukemia, Lymphoid; Liposomes; Middle Aged; Mitoxantrone; Naphthacenes; Prognosis; Teniposide; Transplantation, Homologous; Transplantation, Isogeneic; Vinblastine; Vindesine

1983
The hematologic malignancies. Leukemia, lymphoma, and myeloma.
    Cancer, 1984, Dec-01, Volume: 54, Issue:11 Suppl

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Interferons; Leukemia; Lymphoma; Mechlorethamine; Multiple Myeloma; Prednisone; Procarbazine; Prognosis; Translocation, Genetic; Vincristine

1984
[Etoposide. A new highly effective cytostatic agent in anaplastic small-cell bronchial carcinoma, other solid tumors and hemoblastoses].
    Deutsche medizinische Wochenschrift (1946), 1981, Aug-28, Volume: 106, Issue:35

    Topics: Bronchial Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Small Cell; Cell Division; Choriocarcinoma; Etoposide; Female; Humans; Leukemia; Liver Neoplasms; Lung Neoplasms; Male; Ovarian Neoplasms; Podophyllotoxin; Pregnancy; Testicular Neoplasms; Uterine Neoplasms

1981
Role of etoposide (VP-16) in preparatory regimens for patients with leukemia or lymphoma undergoing allogeneic bone marrow transplantation.
    Bone marrow transplantation, 1994, Volume: 14 Suppl 4

    Topics: Actuarial Analysis; Adolescent; Adult; Bone Marrow Transplantation; Child; Child, Preschool; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Combined Modality Therapy; Cyclophosphamide; Etoposide; Graft vs Host Disease; Humans; Immunosuppressive Agents; Leukemia; Lymphoma; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Survival Rate; Treatment Outcome; Whole-Body Irradiation

1994
Treatment of testicular cancer and the development of secondary malignancies.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:1

    Topics: Antineoplastic Agents; Etoposide; Germinoma; Hodgkin Disease; Humans; Leukemia; Leukemia, Radiation-Induced; Male; Neoplasms, Radiation-Induced; Neoplasms, Second Primary; Testicular Neoplasms

1995
Teniposide: overview of its therapeutic potential in adult cancers.
    Cancer chemotherapy and pharmacology, 1994, Volume: 34 Suppl

    Topics: Acquired Immunodeficiency Syndrome; Adult; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Clinical Trials as Topic; Clinical Trials, Phase I as Topic; Etoposide; Female; Genital Neoplasms, Female; Hodgkin Disease; Humans; Leukemia; Lung Neoplasms; Lymphoma; Lymphoma, Non-Hodgkin; Neoplasms; Sarcoma, Kaposi; Teniposide

1994
Pharmacodynamics and long-term toxicity of etoposide.
    Cancer chemotherapy and pharmacology, 1994, Volume: 34 Suppl

    Topics: Child; Etoposide; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Neoplasms; Podophyllotoxin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Testicular Neoplasms

1994
Clinical pharmacokinetics and pharmacodynamics of epipodophyllotoxins.
    Cancer surveys, 1993, Volume: 17

    Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Resistance; Etoposide; Humans; Leukemia; Neoplasms; Neoplasms, Second Primary; Teniposide; Topoisomerase II Inhibitors

1993
Application of low-dose etoposide therapy for myelodysplastic syndromes.
    Leukemia & lymphoma, 1993, Volume: 12, Issue:1-2

    Topics: Acute Disease; Adult; Aged; Dose-Response Relationship, Drug; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Myelodysplastic Syndromes; Survival Rate

1993
[Secondary leukemias after etoposide chemotherapy].
    Deutsche medizinische Wochenschrift (1946), 1994, May-13, Volume: 119, Issue:19

    Topics: Carcinoma, Bronchogenic; Dose-Response Relationship, Drug; Etoposide; Humans; Leukemia; Lung Neoplasms; Male; Testicular Neoplasms; Time Factors

1994
Use of busulfan containing chemotherapy for conditioning patients with leukemia for bone marrow allografting.
    Bone marrow transplantation, 1993, Volume: 12 Suppl 1

    Topics: Actuarial Analysis; Adult; Bone Marrow Purging; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Cytokines; Etoposide; Graft vs Host Disease; Humans; Leukemia; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Recurrence; Remission Induction; Syndrome; Treatment Outcome; Whole-Body Irradiation

1993
DNA topoisomerase II poisons and inhibitors.
    Cancer chemotherapy and biological response modifiers, 1999, Volume: 18

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; DNA Topoisomerases, Type II; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Humans; Leukemia; Topoisomerase II Inhibitors

1999
VM 26 and VP 16-213: a comparative analysis.
    Cancer, 1977, Volume: 40, Issue:1

    Topics: Animals; Brain Neoplasms; Drug Evaluation; Etoposide; Humans; Kinetics; Leukemia; Lung Neoplasms; Lymphoma; Neoplasms, Experimental; Podophyllotoxin; Teniposide; Urinary Bladder Neoplasms

1977
Etoposide (VP-16-213).
    Cancer treatment reviews, 1979, Volume: 6, Issue:2

    Topics: Adult; Animals; Bone Marrow; Cell Cycle; Child; Digestive System; Drug Therapy, Combination; Etoposide; Female; Humans; Leukemia; Lung Neoplasms; Lymphoma; Male; Mice; Neoplasms; Neoplasms, Experimental; Podophyllotoxin; Rats

1979
Pediatric cancer chemotherapy: an updated review. I. Cis-Diammine--dichloroplatinum II (cisplatin), VM-26 (teniposide), VP-16 (etoposide), mitomycin C.
    Cancer treatment reviews, 1979, Volume: 6, Issue:3

    Topics: Child; Cisplatin; Clinical Trials as Topic; Drug Administration Schedule; Etoposide; Humans; Leukemia; Mitomycins; Neoplasms; Podophyllotoxin; Teniposide

1979
Purging multidrug resistant cells from bone marrow.
    Progress in clinical and biological research, 1992, Volume: 377

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Bone Marrow; Bone Marrow Purging; Bone Marrow Transplantation; Complement System Proteins; Drug Resistance; Etoposide; Humans; Leukemia; Mice

1992
Conditioning regimens for allogeneic bone marrow transplantation.
    Blood reviews, 1992, Volume: 6, Issue:4

    Topics: Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Purging; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Cytarabine; Etoposide; Humans; Leukemia; Lymphocyte Depletion; Melphalan; T-Lymphocytes; Transplantation, Homologous; Whole-Body Irradiation

1992
High-dose etoposide (VP-16)-containing preparatory regimens in allogeneic and autologous bone marrow transplantation for hematologic malignancies.
    Seminars in oncology, 1992, Volume: 19, Issue:6 Suppl 13

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Chemotherapy, Adjuvant; Etoposide; Humans; Leukemia; Lymphoma; Multiple Myeloma; Whole-Body Irradiation

1992
Autotransplants in leukemia: current state, future progress.
    Leukemia research, 1991, Volume: 15, Issue:9

    Topics: Bone Marrow Transplantation; Cyclophosphamide; Etoposide; Graft vs Host Disease; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Transplantation, Autologous; Twins, Monozygotic

1991
Aleukemic leukemia cutis.
    Journal of the American Academy of Dermatology, 1990, Volume: 22, Issue:2 Pt 2

    Topics: Adolescent; Adult; Aged; Biopsy; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Radiography; Skin Neoplasms

1990
Cell kinetics as related to treatment of patients with acute nonlymphoid leukemia.
    The American journal of pediatric hematology/oncology, 1985,Winter, Volume: 7, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bone Marrow; Bone Marrow Cells; Cell Cycle; Child; Cytarabine; Daunorubicin; Doxorubicin; Etoposide; Flow Cytometry; Hematopoietic Stem Cells; Humans; Hydrocortisone; Leukemia; Methotrexate; Mitotic Index; Neoplastic Stem Cells; Prednisone; Prognosis; Vincristine

1985
Pharmacological purging of bone marrow with reference to autografting.
    Clinics in haematology, 1986, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Animals; Bleomycin; Bone Marrow; Bone Marrow Transplantation; Cell Separation; Child; Child, Preschool; Clinical Trials as Topic; Cyclophosphamide; Drug Evaluation; Etoposide; Graft vs Host Disease; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma; Lysophosphatidylcholines; Methylprednisolone; Neoplasms, Experimental; Phospholipid Ethers; Pyrimidinones; Transplantation, Autologous; Transplantation, Isogeneic

1986
Pharmacological bone marrow purging with drugs other than cyclophosphamide derivatives.
    Bone marrow transplantation, 1989, Volume: 4 Suppl 1

    Topics: Animals; Antineoplastic Agents; Bleomycin; Bone Marrow; Bone Marrow Transplantation; Etoposide; Humans; Leukemia; Lymphoma; Mice; Mice, Inbred C57BL; Neoplastic Stem Cells; Preoperative Care

1989
[Use of recombinant hematopoietic growth factors after chemotherapy and high-dose chemo-radiotherapy].
    Haematologica, 1989, Volume: 74, Issue:5 Suppl

    Topics: Anemia, Aplastic; Antineoplastic Agents; Colony-Stimulating Factors; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Drug Evaluation; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Melphalan; Neoplasms; Radiotherapy

1989
Etoposide: fifteen years experience.
    Bone marrow transplantation, 1989, Volume: 4 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Etoposide; Hodgkin Disease; Humans; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Lomustine; Melphalan; Mitoxantrone

1989
Etoposide in leukemia, lymphoma and bone marrow transplantation.
    Leukemia research, 1989, Volume: 13, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Etoposide; Humans; Leukemia; Lymphoma

1989
Etoposide (VP-16-213). Current status of an active anticancer drug.
    The New England journal of medicine, 1985, Mar-14, Volume: 312, Issue:11

    Topics: Animals; Carcinoma, Small Cell; Clinical Trials as Topic; DNA; Drug Administration Schedule; Drug Evaluation; Drug Evaluation, Preclinical; Drug Resistance; Etoposide; Female; Hodgkin Disease; Humans; Leukemia; Lung Neoplasms; Lymphoma; Male; Mice; Podophyllotoxin; Testicular Neoplasms; Tissue Distribution

1985
Overview of the clinical relevance of autologous bone marrow transplantation.
    Clinics in haematology, 1986, Volume: 15, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Drug Evaluation; Drug Resistance; Etoposide; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma; Melphalan; Neoplasm Recurrence, Local; Neoplasms; Thioguanine; Transplantation, Autologous

1986
Indications for and benefits of intensive therapies in treatment of childhood cancers.
    Cancer, 1986, Jul-15, Volume: 58, Issue:2 Suppl

    Topics: Acute Disease; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Etoposide; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma; Melphalan; Methotrexate; Neoplasms; Osteosarcoma; Risk; Sarcoma, Ewing

1986

Trials

51 trial(s) available for etoposide and Leukemia

ArticleYear
Outcome of relapse in children and adolescents with B-cell non-Hodgkin lymphoma and mature acute leukemia: A report from the French LMB study.
    Pediatric blood & cancer, 2019, Volume: 66, Issue:9

    Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Carboplatin; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; France; Humans; Ifosfamide; Infant; Leukemia; Lymphoma, Large B-Cell, Diffuse; Male; Prospective Studies; Recurrence; Rituximab; Survival Rate

2019
Improved outcome of adult Burkitt lymphoma/leukemia with rituximab and chemotherapy: report of a large prospective multicenter trial.
    Blood, 2014, Dec-18, Volume: 124, Issue:26

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antigens, CD20; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Cyclophosphamide; Cytarabine; Disease-Free Survival; Etoposide; Female; Humans; Ifosfamide; Immunotherapy; Injections, Spinal; Leukemia; Male; Methotrexate; Middle Aged; Prognosis; Prospective Studies; Remission Induction; Rituximab; Young Adult

2014
Safety, Pharmacokinetics, and Efficacy of Palifermin in Children and Adolescents with Acute Leukemias Undergoing Myeloablative Therapy and Allogeneic Hematopoietic Stem Cell Transplantation: A Pediatric Blood and Marrow Transplant Consortium Trial.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2016, Volume: 22, Issue:7

    Topics: Acute Disease; Adolescent; Child; Child, Preschool; Cyclophosphamide; Etoposide; Female; Fibroblast Growth Factor 7; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Infant; Leukemia; Male; Myeloablative Agonists; Stomatitis; Transplantation, Homologous; Treatment Outcome; Whole-Body Irradiation

2016
Phase I Trial of Total Marrow and Lymphoid Irradiation Transplantation Conditioning in Patients with Relapsed/Refractory Acute Leukemia.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2017, Volume: 23, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Bone Marrow; Cyclophosphamide; Dose-Response Relationship, Radiation; Etoposide; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Lymphatic Irradiation; Male; Middle Aged; Recurrence; Salvage Therapy; Survival Analysis; Transplantation Conditioning; Young Adult

2017
A multi-center phase I study of clofarabine, etoposide and cyclophosphamide in combination in pediatric patients with refractory or relapsed acute leukemia.
    Leukemia, 2009, Volume: 23, Issue:12

    Topics: Acute Disease; Adenine Nucleotides; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Clofarabine; Cyclophosphamide; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Infant; Leukemia; Leukemia, Myeloid, Acute; Maximum Tolerated Dose; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Salvage Therapy; Treatment Outcome; Young Adult

2009
Phase-2 trial of an intensified conditioning regimen for allogeneic hematopoietic cell transplant for poor-risk leukemia.
    Bone marrow transplantation, 2011, Volume: 46, Issue:9

    Topics: Adult; Busulfan; Combined Modality Therapy; Disease-Free Survival; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Male; Middle Aged; Recurrence; Risk Factors; Transplantation Conditioning; Transplantation, Homologous; Whole-Body Irradiation; Young Adult

2011
Treatment of refractory acute leukemia with timed sequential chemotherapy using topotecan followed by etoposide + mitoxantrone (T-EM) and correlation with topoisomerase II levels.
    Leukemia & lymphoma, 2002, Volume: 43, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; DNA Fragmentation; DNA Topoisomerases, Type II; Enzyme Induction; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Mitoxantrone; Topotecan

2002
Peripheral blood stem cell collection in children with acute leukemia: effectiveness of the 'DIAVE' mobilizing regimen.
    Bone marrow transplantation, 2002, Volume: 30, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Cell Count; Child; Child, Preschool; Cytarabine; Dexamethasone; Etoposide; Graft Survival; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Humans; Idarubicin; Leukapheresis; Leukemia; Peripheral Blood Stem Cell Transplantation; Vincristine

2002
A phase I dose-escalation study of etoposide continuous infusion added to busulphan/cyclophosphamide as conditioning prior to autologous or allogeneic stem cell transplantation.
    Bone marrow transplantation, 2002, Volume: 30, Issue:10

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cyclophosphamide; Etoposide; Female; Graft Survival; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Lymphoma; Male; Maximum Tolerated Dose; Middle Aged; Mucous Membrane; Stomatitis; Transplantation Conditioning; Transplantation, Autologous; Transplantation, Homologous

2002
Standard and increased-dose BEACOPP chemotherapy compared with COPP-ABVD for advanced Hodgkin's disease.
    The New England journal of medicine, 2003, Jun-12, Volume: 348, Issue:24

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Cyclophosphamide; Dacarbazine; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Female; Hodgkin Disease; Humans; Leukemia; Male; Middle Aged; Neoplasm Staging; Neoplasms, Second Primary; Prednisone; Procarbazine; Survival Analysis; Vinblastine; Vincristine

2003
Therapy-related myelodysplasia and leukemia occur infrequently following VP-16 priming and autotransplantation without total body irradiation.
    Bone marrow transplantation, 2004, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Aged; Breast Neoplasms; Etoposide; Female; Hematopoietic Stem Cell Mobilization; Humans; Incidence; Leukemia; Lymphoma; Male; Middle Aged; Neoplasms, Second Primary; Neural Tube Defects; Peripheral Blood Stem Cell Transplantation; Probability; Transplantation, Autologous

2004
Glomerular dysfunction, independent of tubular dysfunction, induced by antineoplastic chemotherapy in children.
    Pediatrics international : official journal of the Japan Pediatric Society, 2004, Volume: 46, Issue:5

    Topics: Acute Disease; Adolescent; Albuminuria; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Creatinine; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Glomerular Filtration Rate; Humans; Kidney Tubules; Leukemia; Lymphoma; Methotrexate; Neoplasms; Neuroblastoma; Osteosarcoma; Proteinuria; Rhabdomyosarcoma; Vincristine

2004
A phase I and pharmacologic study of idarubicin, cytarabine, etoposide, and the multidrug resistance protein (MDR1/Pgp) inhibitor PSC-833 in patients with refractory leukemia.
    Leukemia research, 2005, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclosporins; Cytarabine; Drug Interactions; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Idarubicin; Leukemia; Male; Maximum Tolerated Dose; Middle Aged; Treatment Outcome

2005
Donor lymphocyte infusion for the treatment of leukemia relapse after HLA-mismatched/haploidentical T-cell-replete hematopoietic stem cell transplantation.
    Haematologica, 2007, Volume: 92, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Agents; Benzamides; Child; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Graft vs Host Disease; Graft vs Leukemia Effect; Haplotypes; Histocompatibility; HLA Antigens; Humans; Imatinib Mesylate; Immunosuppressive Agents; Kaplan-Meier Estimate; Leukemia; Lymphocyte Transfusion; Male; Methotrexate; Mitoxantrone; Pancytopenia; Peripheral Blood Stem Cell Transplantation; Piperazines; Pyrimidines; Recurrence; Remission Induction; Salvage Therapy; Tissue Donors; Treatment Outcome

2007
VP-16-213 (etoposide): the mandrake root from Issyk-Kul.
    The American journal of medicine, 1982, Volume: 72, Issue:1

    Topics: Animals; Breast Neoplasms; Carcinoma, Small Cell; Cell Cycle; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Dysgerminoma; Etoposide; Female; Humans; Leukemia; Lung Neoplasms; Lymphoma; Mice; Podophyllotoxin

1982
[New antineoplastic drugs of the podophyllotoxin derivative group].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1983, Jan-03, Volume: 38, Issue:1

    Topics: Adult; Child; Clinical Trials as Topic; Etoposide; Female; Humans; Leukemia; Lung Neoplasms; Lymphoma; Neoplasms; Ovarian Neoplasms; Podophyllotoxin; Teniposide; Urinary Bladder Neoplasms

1983
[Phase II study of etoposide (NK 171) in advanced hematological malignancies].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:8

    Topics: Administration, Oral; Adolescent; Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Infusions, Parenteral; Leukemia; Leukopenia; Lymphoma; Male; Middle Aged; Nausea; Podophyllotoxin; Prednisolone; Thrombocytosis; Vincristine

1984
Peripheral blood stem cell mobilization with chemotherapy and granulocyte-colony stimulating factor in patients with hematological malignancies.
    The Tokai journal of experimental and clinical medicine, 1994, Volume: 19, Issue:3-6

    Topics: Adolescent; Adult; Antigens, CD34; Colony-Forming Units Assay; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Leukapheresis; Leukemia; Leukocyte Count; Lymphoma; Male; Middle Aged

1994
Continuous infusion etoposide/carboplatin for treatment of refractory acute leukemia.
    American journal of clinical oncology, 1995, Volume: 18, Issue:5

    Topics: Adolescent; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Etoposide; Female; Humans; Infusions, Intravenous; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Salvage Therapy

1995
Bone marrow purging with etoposide/methylprednisolone in patients undergoing autologous bone marrow transplantation.
    Progress in clinical and biological research, 1994, Volume: 389

    Topics: Adolescent; Adult; Aged; Bone Marrow Purging; Bone Marrow Transplantation; Child; Etoposide; Humans; Leukemia; Leukocyte Count; Lymphoma; Methylprednisolone; Middle Aged; Neutrophils; Platelet Count; Transplantation, Autologous

1994
Role of etoposide (VP-16) in preparatory regimens for patients with leukemia or lymphoma undergoing allogeneic bone marrow transplantation.
    Bone marrow transplantation, 1994, Volume: 14 Suppl 4

    Topics: Actuarial Analysis; Adolescent; Adult; Bone Marrow Transplantation; Child; Child, Preschool; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Combined Modality Therapy; Cyclophosphamide; Etoposide; Graft vs Host Disease; Humans; Immunosuppressive Agents; Leukemia; Lymphoma; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Survival Rate; Treatment Outcome; Whole-Body Irradiation

1994
Maximum-tolerated doses of ifosfamide, carboplatin, and etoposide given over 6 days followed by autologous stem-cell rescue: toxicity profile.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Drug Tolerance; Etoposide; Female; Germinoma; Hematopoietic Stem Cell Transplantation; Hodgkin Disease; Humans; Ifosfamide; Leukemia; Lymphoma, Non-Hodgkin; Male; Middle Aged; Ovarian Neoplasms; Prognosis; Sarcoma; Testicular Neoplasms; Transplantation, Autologous

1995
Autologous bone marrow transplantation with alkyl-lysophospholipid-purged marrow.
    Journal of hematotherapy, 1993,Spring, Volume: 2, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Bone Marrow Transplantation; Combined Modality Therapy; Cryopreservation; Cyclophosphamide; Cytarabine; Etoposide; Female; Hematopoietic Stem Cells; Humans; Infections; Leukemia; Life Tables; Male; Middle Aged; Neoplastic Stem Cells; Phospholipid Ethers; Salvage Therapy; Survival Analysis; Tissue Preservation; Whole-Body Irradiation

1993
Prognostic value of immunophenotyping in acute myeloid leukemia. Australian Leukaemia Study Group.
    Blood, 1994, Aug-15, Volume: 84, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Etoposide; Follow-Up Studies; HLA-DR Antigens; Humans; Immunophenotyping; Leukemia; Middle Aged; Predictive Value of Tests; Prognosis; Survival Analysis; Time Factors

1994
Phase I trial of continuous infusion carboplatin and etoposide in children with refractory acute leukemia: a Pediatric Oncology Group study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1994, Volume: 12, Issue:9

    Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carboplatin; Child; Child, Preschool; Diarrhea; Drug Administration Schedule; Etoposide; Female; Humans; Infections; Infusions, Intravenous; Leukemia; Male; Remission Induction; United States

1994
Cyclosporin A as a modifier agent in the salvage treatment of acute leukemia (AL).
    Leukemia, 1993, Volume: 7, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Cyclosporine; Etoposide; Female; Humans; Leukemia; Male; Membrane Glycoproteins; Middle Aged; Mitoxantrone

1993
[High-dose busulfan, VP-16 and ACNU therapy with stem cell transplantation for the treatment of children with acute leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1993, Volume: 34, Issue:5

    Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Carmustine; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Male; Nimustine

1993
LCH-I: a randomized trial of etoposide vs. vinblastine in disseminated Langerhans cell histiocytosis. The Histiocyte Society.
    Medical and pediatric oncology, 1994, Volume: 23, Issue:2

    Topics: Drug Administration Schedule; Etoposide; Histiocytosis, Langerhans-Cell; Humans; Leukemia; Methylprednisolone; Vinblastine

1994
A phase I trial of carboplatin and etoposide given as continuous infusions to adults with leukemia.
    Leukemia, 1993, Volume: 7, Issue:10

    Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Carboplatin; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Female; Humans; Infusions, Intravenous; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma

1993
A prospective randomized comparison of total body irradiation-etoposide versus busulfan-cyclophosphamide as preparatory regimens for bone marrow transplantation in patients with leukemia who were not in first remission: a Southwest Oncology Group study.
    Blood, 1993, Apr-15, Volume: 81, Issue:8

    Topics: Adolescent; Adult; Aged; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Prospective Studies; Remission Induction; Risk Factors; Whole-Body Irradiation

1993
Comparison of four cytokine regimens for mobilization of peripheral blood stem cells: IL-3 alone and combined with GM-CSF or G-CSF.
    Bone marrow transplantation, 1996, Volume: 17, Issue:2

    Topics: Adult; Bone Marrow; Breast Neoplasms; Busulfan; Carboplatin; Carmustine; Cyclophosphamide; Drug Administration Schedule; Drug Synergism; Etoposide; Female; Graft Survival; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Interleukin-3; Leukapheresis; Leukemia; Leukocyte Count; Lymphoma; Male; Middle Aged; Neutrophils; Prospective Studies; Thiotepa; Whole-Body Irradiation

1996
[Treatment of refractory hematologic malignancies by combination of cytarabine ocfosfate and etoposide].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:12

    Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleotides; Cytidine Monophosphate; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia; Male; Middle Aged

1996
[Chemotherapy schedules and bacteremia in adult patients with acute leukemia].
    Medicina, 1996, Volume: 56, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Cytarabine; Daunorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Leukemia; Male; Mitoxantrone; Neutropenia; Risk Factors

1996
High risk of leukemia after short-term dose-intensive chemotherapy in young patients with solid tumors.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:9

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Ifosfamide; Leukemia; Male; Myelodysplastic Syndromes; Neoplasms; Neoplasms, Second Primary; Prospective Studies; Risk Factors; Vincristine

1998
High-dose etoposide with granulocyte colony-stimulating factor for mobilization of peripheral blood progenitor cells: efficacy and toxicity at three dose levels.
    British journal of cancer, 1998, Volume: 78, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Etoposide; Female; Germinoma; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hodgkin Disease; Humans; Leukemia; Lymphoma, Non-Hodgkin; Male; Middle Aged; Multiple Myeloma; Neoplasms

1998
Moderate dose escalation for advanced stage Hodgkin's disease using the bleomycin, etoposide, adriamycin, cyclophosphamide, vincristine, procarbazine, and prednisone scheme and adjuvant radiotherapy: a study of the German Hodgkin's Lymphoma Study Group.
    Blood, 1998, Dec-15, Volume: 92, Issue:12

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Hodgkin Disease; Humans; Leukemia; Male; Middle Aged; Neoplasms, Second Primary; Prednisone; Procarbazine; Radiotherapy, Adjuvant; Recombinant Proteins; Remission Induction; Survival Rate; Treatment Outcome; Vincristine

1998
Allogeneic bone marrow transplantation for children with acute leukemia: cytoreduction with fractionated total body irradiation, high-dose etoposide and cyclophosphamide.
    Bone marrow transplantation, 2000, Volume: 25, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Blood Grouping and Crossmatching; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Evaluation; Drug-Related Side Effects and Adverse Reactions; Etoposide; Graft Survival; Graft vs Host Disease; Humans; Infant; Leukemia; Myeloablative Agonists; Nuclear Family; Recurrence; Stomatitis; Survival Rate; Transplantation, Homologous; Whole-Body Irradiation

2000
Mitoxantrone, etoposide, carboplatinum and ara-C combination therapy (MECA) in refractory and relapsed acute leukemia.
    Leukemia & lymphoma, 2000, Volume: 39, Issue:5-6

    Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cytarabine; Disease-Free Survival; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Male; Middle Aged; Mitoxantrone; Recurrence; Risk Factors; Salvage Therapy; Treatment Outcome

2000
Therapeutic trials with VP-16-213 and VM-26: active agents in small cell lung cancer, non-Hodgkin's lymphomas, and other malignancies.
    Cancer treatment reports, 1979, Volume: 63, Issue:8

    Topics: Alopecia; Carcinoma, Small Cell; Clinical Trials as Topic; Drug Evaluation; Etoposide; Humans; Leukemia; Leukopenia; Lung Neoplasms; Lymphoma; Podophyllotoxin; Teniposide

1979
Pediatric cancer chemotherapy: an updated review. I. Cis-Diammine--dichloroplatinum II (cisplatin), VM-26 (teniposide), VP-16 (etoposide), mitomycin C.
    Cancer treatment reviews, 1979, Volume: 6, Issue:3

    Topics: Child; Cisplatin; Clinical Trials as Topic; Drug Administration Schedule; Etoposide; Humans; Leukemia; Mitomycins; Neoplasms; Podophyllotoxin; Teniposide

1979
Etoposide, cyclophosphamide and fractionated total body irradiation as a preparative regimen for marrow transplantation in patients with advanced hematological malignancies: a phase I study.
    Bone marrow transplantation, 1992, Volume: 10, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Cyclophosphamide; Etoposide; Graft vs Host Disease; Humans; Leukemia; Lymphoma; Middle Aged; Transplantation, Autologous; Transplantation, Homologous; Whole-Body Irradiation

1992
What role for prednisone in prevention of acute graft-versus-host disease in patients undergoing marrow transplants?
    Blood, 1990, Sep-01, Volume: 76, Issue:5

    Topics: Acute Disease; Anemia, Aplastic; Bone Marrow Transplantation; Chronic Disease; Clinical Trials as Topic; Cyclophosphamide; Cyclosporins; Etoposide; Female; Follow-Up Studies; Graft vs Host Disease; Histocompatibility Testing; Humans; Immunosuppression Therapy; Leukemia; Male; Methotrexate; Myelodysplastic Syndromes; Prednisone; Random Allocation; Risk Factors; Whole-Body Irradiation

1990
Pharmacological purging of bone marrow with reference to autografting.
    Clinics in haematology, 1986, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Animals; Bleomycin; Bone Marrow; Bone Marrow Transplantation; Cell Separation; Child; Child, Preschool; Clinical Trials as Topic; Cyclophosphamide; Drug Evaluation; Etoposide; Graft vs Host Disease; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma; Lysophosphatidylcholines; Methylprednisolone; Neoplasms, Experimental; Phospholipid Ethers; Pyrimidinones; Transplantation, Autologous; Transplantation, Isogeneic

1986
Induction failures in childhood acute nonlymphocytic leukemia: etoposide/5-azacytidine for cases refractory to daunorubicin/cytarabine.
    Medical and pediatric oncology, 1986, Volume: 14, Issue:5

    Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Child; Clinical Trials as Topic; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia; Male

1986
The treatment of indolent lymphomas: watchful waiting v aggressive combined modality treatment.
    Seminars in hematology, 1988, Volume: 25, Issue:2 Suppl 2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Evaluation Studies as Topic; Humans; Leucovorin; Leukemia; Leukemia, Radiation-Induced; Lymph Nodes; Lymphoma, Non-Hodgkin; Mechlorethamine; Methotrexate; Neoplasms, Multiple Primary; Neoplasms, Radiation-Induced; Palliative Care; Prednisone; Procarbazine; Random Allocation; Vincristine

1988
Clinical trial of continuous infusion verapamil, bolus vinblastine, and continuous infusion VP-16 in drug-resistant pediatric tumors.
    Cancer research, 1989, Feb-15, Volume: 49, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Child; Child, Preschool; Clinical Trials as Topic; Etoposide; Humans; Infusions, Intravenous; Leukemia; Liver Neoplasms; Neuroblastoma; Verapamil; Vinblastine

1989
Etoposide (VP-16-213). Current status of an active anticancer drug.
    The New England journal of medicine, 1985, Mar-14, Volume: 312, Issue:11

    Topics: Animals; Carcinoma, Small Cell; Clinical Trials as Topic; DNA; Drug Administration Schedule; Drug Evaluation; Drug Evaluation, Preclinical; Drug Resistance; Etoposide; Female; Hodgkin Disease; Humans; Leukemia; Lung Neoplasms; Lymphoma; Male; Mice; Podophyllotoxin; Testicular Neoplasms; Tissue Distribution

1985
[A study of B-triple V (behenoyl-ara C, etoposide, vincristine, vinblastine) in acute leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1988, Volume: 29, Issue:4

    Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Vinblastine; Vincristine

1988
Early intensification of chemotherapy for childhood acute nonlymphoblastic leukemia: improved remission induction with a five-drug regimen including etoposide.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Clinical Trials as Topic; Etoposide; Female; Humans; Infant; Infant, Newborn; Leukemia; Male; Prognosis; Remission Induction

1988
Overview of the clinical relevance of autologous bone marrow transplantation.
    Clinics in haematology, 1986, Volume: 15, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Drug Evaluation; Drug Resistance; Etoposide; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma; Melphalan; Neoplasm Recurrence, Local; Neoplasms; Thioguanine; Transplantation, Autologous

1986
The epipodophyllotoxin VP16-213 in combination chemotherapy for adults with acute nonlymphoblastic leukaemia.
    Haematology and blood transfusion, 1985, Volume: 29

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Doxorubicin; Etoposide; Humans; Leukemia; Podophyllotoxin; Thioguanine

1985

Other Studies

266 other study(ies) available for etoposide and Leukemia

ArticleYear
Synthesis and pharmacological evaluation of isoindolo[1,2-b]quinazolinone and isoindolo[2,1-a]benzimidazole derivatives related to the antitumor agent batracylin.
    Journal of medicinal chemistry, 1994, Sep-30, Volume: 37, Issue:20

    Topics: Animals; Antineoplastic Agents; DNA; Humans; Indoles; Isoindoles; Leukemia; Liver; Pyridones; Pyrimidines; Quinazolines; Rats; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1994
Cytotoxic oxoisoaporphine alkaloids from Menispermum dauricum.
    Journal of natural products, 2001, Volume: 64, Issue:7

    Topics: Adenocarcinoma; Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cytochrome P-450 Enzyme Inhibitors; Drugs, Chinese Herbal; Enzyme Inhibitors; Female; Humans; Leukemia; Lung Neoplasms; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Molecular Structure; Plant Roots; Plants, Medicinal; Porphyrins; Tumor Cells, Cultured

2001
Differential Targeting of Human Topoisomerase II Isoforms with Small Molecules.
    Journal of medicinal chemistry, 2015, Jun-11, Volume: 58, Issue:11

    Topics: Animals; Antigens, Neoplasm; Cells, Cultured; DNA Topoisomerases, Type II; DNA-Binding Proteins; Etoposide; Humans; Leukemia; Mice; Mice, Knockout; Models, Molecular; Molecular Structure; Poly-ADP-Ribose Binding Proteins; Small Molecule Libraries; Structure-Activity Relationship; Topoisomerase II Inhibitors

2015
Discovery of antitumor anthra[2,3-b]furan-3-carboxamides: Optimization of synthesis and evaluation of antitumor properties.
    European journal of medicinal chemistry, 2016, Apr-13, Volume: 112

    Topics: Animals; Anthracenes; Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Furans; Humans; Leukemia; Mice; Neoplasms; Protein Kinase Inhibitors; Structure-Activity Relationship; Topoisomerase Inhibitors

2016
Design, synthesis and evaluation of the multidrug resistance-reversing activity of pyridine acid esters of podophyllotoxin in human leukemia cells.
    Bioorganic & medicinal chemistry letters, 2016, 09-15, Volume: 26, Issue:18

    Topics: Cell Line, Tumor; Drug Design; Drug Resistance, Multiple; Esters; Humans; Inhibitory Concentration 50; Leukemia; MAP Kinase Signaling System; Podophyllotoxin; Pyridines

2016
KMT2A-MAML2 rearrangement emerged and regressed during neuroblastoma therapy without leukemia after 12.8-year follow-up.
    Pediatric blood & cancer, 2022, Volume: 69, Issue:1

    Topics: Etoposide; Follow-Up Studies; Gene Rearrangement; Histone-Lysine N-Methyltransferase; Humans; Leukemia; Myeloid-Lymphoid Leukemia Protein; Neuroblastoma; Trans-Activators; Transcription Factors

2022
The effect of apigenin and chemotherapy combination treatments on apoptosis-related genes and proteins in acute leukaemia cell lines.
    Scientific reports, 2022, 05-25, Volume: 12, Issue:1

    Topics: Apigenin; Apoptosis; Apoptosis Regulatory Proteins; Cell Line; Cyclophosphamide; Drug Therapy, Combination; Etoposide; Humans; Leukemia; Mitochondrial Proteins

2022
Use of CRISPR/Cas9 with homology-directed repair to silence the human topoisomerase IIα intron-19 5' splice site: Generation of etoposide resistance in human leukemia K562 cells.
    PloS one, 2022, Volume: 17, Issue:5

    Topics: Antigens, Neoplasm; CRISPR-Cas Systems; DNA Topoisomerases, Type II; Etoposide; Humans; Introns; K562 Cells; Leukemia; RNA Splice Sites; RNA, Messenger

2022
Inhibition of NAMPT sensitizes MOLT4 leukemia cells for etoposide treatment through the SIRT2-p53 pathway.
    Leukemia research, 2018, Volume: 69

    Topics: Cell Death; Cell Line, Tumor; Cytokines; Enzyme Inhibitors; Etoposide; Humans; Leukemia; Nicotinamide Phosphoribosyltransferase; Signal Transduction; Sirtuin 2; Topoisomerase II Inhibitors; Tumor Suppressor Protein p53

2018
Activation of Rac1 GTPase promotes leukemia cell chemotherapy resistance, quiescence and niche interaction.
    Molecular oncology, 2013, Volume: 7, Issue:5

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Movement; Cells, Cultured; Drug Resistance, Neoplasm; Etoposide; Humans; Immunohistochemistry; Leukemia; Mice; Mice, SCID; rac1 GTP-Binding Protein; Reverse Transcriptase Polymerase Chain Reaction; Xenograft Model Antitumor Assays

2013
Wogonin attenuates etoposide-induced oxidative DNA damage and apoptosis via suppression of oxidative DNA stress and modulation of OGG1 expression.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 59

    Topics: Animals; Anticarcinogenic Agents; Antioxidants; Apoptosis; Bone Marrow Cells; DNA Damage; DNA Glycosylases; Dose-Response Relationship, Drug; Etoposide; Flavanones; Gene Expression Regulation; Leukemia; Male; Mice; Micronucleus Tests; Mutagenicity Tests; Oxidative Stress; Random Allocation; RNA, Messenger; Topoisomerase II Inhibitors

2013
Down-regulation of Mcl-1 by small interference RNA induces apoptosis and sensitizes HL-60 leukemia cells to etoposide.
    Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Proliferation; Etoposide; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Leukemia; Myeloid Cell Leukemia Sequence 1 Protein; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Tumor Cells, Cultured

2014
Etoposide quinone is a covalent poison of human topoisomerase IIβ.
    Biochemistry, 2014, May-20, Volume: 53, Issue:19

    Topics: DNA; DNA Topoisomerases, Type II; DNA-Binding Proteins; Etoposide; Humans; Leukemia; Neoplasm Proteins; Quinones; Topoisomerase II Inhibitors

2014
Inhibition of miR-17 and miR-20a by oridonin triggers apoptosis and reverses chemoresistance by derepressing BIM-S.
    Cancer research, 2014, Aug-15, Volume: 74, Issue:16

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Cell Growth Processes; Cytarabine; Diterpenes, Kaurane; Down-Regulation; Etoposide; HL-60 Cells; Humans; K562 Cells; Leukemia; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Microscopy, Confocal; Proto-Oncogene Proteins; Transfection; Up-Regulation

2014
Schedule-dependent cytotoxicity of Etoposide and cyclophosphamide in P-glycoprotein-expressing human leukemic K-562 cells.
    Biological & pharmaceutical bulletin, 2014, Volume: 37, Issue:8

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Cycle; Cell Survival; Cyclophosphamide; Drug Administration Schedule; Etoposide; Humans; K562 Cells; Leukemia

2014
Structure-based design, synthesis and biological testing of etoposide analog epipodophyllotoxin-N-mustard hybrid compounds designed to covalently bind to topoisomerase II and DNA.
    Bioorganic & medicinal chemistry, 2014, Nov-01, Volume: 22, Issue:21

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA; DNA Breaks, Double-Stranded; DNA Topoisomerases, Type II; Etoposide; Humans; Leukemia; Molecular Docking Simulation; Mustard Compounds; Neoplasms; Podophyllotoxin; Topoisomerase II Inhibitors

2014
Environmental and chemotherapeutic agents induce breakage at genes involved in leukemia-causing gene rearrangements in human hematopoietic stem/progenitor cells.
    Mutation research, 2015, Volume: 779

    Topics: Benzene; Bone Marrow Cells; Chromosome Breakage; Core Binding Factor beta Subunit; Diethylnitrosamine; DNA Damage; DNA Topoisomerases, Type II; Doxorubicin; Etoposide; Gene Rearrangement; Genome, Human; Hematopoietic Stem Cells; Histone-Lysine N-Methyltransferase; Humans; Leukemia; Myeloid-Lymphoid Leukemia Protein; Primary Cell Culture

2015
Dysregulation of the DNA Damage Response and KMT2A Rearrangement in Fetal Liver Hematopoietic Cells.
    PloS one, 2015, Volume: 10, Issue:12

    Topics: Animals; Bone Marrow Cells; Carcinogenesis; Cell Cycle; Chromosome Breakage; DNA Breaks, Double-Stranded; DNA Damage; Etoposide; Female; Fetus; Gene Rearrangement; Hematopoietic Stem Cells; Histone-Lysine N-Methyltransferase; Histones; Injections, Intraperitoneal; Leukemia; Liver; Maternal Exposure; Mice, Inbred C57BL; Mice, Knockout; Myeloid-Lymphoid Leukemia Protein

2015
MYC/BCL2 double-hit lymphoma/leukemia mimicking acute leukemia at initial presentation.
    Blood, 2016, Feb-25, Volume: 127, Issue:8

    Topics: Abnormal Karyotype; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Autografts; Cyclophosphamide; Dexamethasone; Diagnosis, Differential; Doxorubicin; Etoposide; Fatal Outcome; Flow Cytometry; Genes, myc; Hematopoietic Stem Cell Transplantation; Humans; Immunophenotyping; In Situ Hybridization, Fluorescence; Leukemia; Leukocytosis; Lymphoma, B-Cell; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Multiple Primary; Prednisone; Proto-Oncogene Proteins c-bcl-2; Rituximab; Vincristine

2016
Quercetin alters the DNA damage response in human hematopoietic stem and progenitor cells via TopoII- and PI3K-dependent mechanisms synergizing in leukemogenic rearrangements.
    International journal of cancer, 2017, 02-15, Volume: 140, Issue:4

    Topics: Adult; Ascorbic Acid; Cell Culture Techniques; Cell Transformation, Neoplastic; Cells, Cultured; Colony-Forming Units Assay; DNA Damage; DNA Repair; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Etoposide; Female; Genistein; Hematopoietic Stem Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Infant; Leukemia; Maternal-Fetal Exchange; Myeloid-Lymphoid Leukemia Protein; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pregnancy; Quercetin; Signal Transduction; Topoisomerase II Inhibitors

2017
Factors and Costs Associated With Delay in Treatment Initiation and Prolonged Length of Stay With Inpatient EPOCH Chemotherapy in Patients With Hematologic Malignancies.
    Cancer investigation, 2017, Mar-16, Volume: 35, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Etoposide; Female; Health Care Costs; Humans; Inpatients; Length of Stay; Leukemia; Lymphoma; Male; Middle Aged; Prednisone; Treatment Outcome; Vincristine

2017
Reduced risk of secondary leukemia with fewer cycles of dose-intensive induction chemotherapy in patients with neuroblastoma.
    Pediatric blood & cancer, 2009, Volume: 53, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia; Male; Myelodysplastic Syndromes; Neuroblastoma; Prospective Studies; Remission Induction; Risk Reduction Behavior; Topoisomerase II Inhibitors; Vincristine; Young Adult

2009
Low toxicity of a conditioning with 8-Gy total body irradiation, fludarabine and cyclophosphamide as preparative regimen for allogeneic hematopoietic stem cell transplantation in pediatric hematological malignancies.
    Pediatric transplantation, 2009, Volume: 13, Issue:6

    Topics: Adolescent; Child; Child, Preschool; Cyclophosphamide; Disease-Free Survival; Etoposide; Female; Graft Survival; Hematopoietic Stem Cell Transplantation; HLA Antigens; Humans; Infant; Leukemia; Male; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Vidarabine; Whole-Body Irradiation

2009
Molecular targeting of MLL-rearranged leukemia cell lines with the synthetic peptide PFWT synergistically enhances the cytotoxic effect of established chemotherapeutic agents.
    Leukemia research, 2009, Volume: 33, Issue:7

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Cycle; Cell Proliferation; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 4; Chromosomes, Human, Pair 9; Colony-Forming Units Assay; Cytarabine; DNA-Binding Proteins; Drug Synergism; Etoposide; Gene Rearrangement; Histone-Lysine N-Methyltransferase; Humans; Leukemia; Myeloid-Lymphoid Leukemia Protein; Necrosis; Nuclear Proteins; Peptide Fragments; Transcriptional Elongation Factors; Translocation, Genetic; Tumor Cells, Cultured

2009
PU.1, a novel caspase-3 substrate, partially contributes to chemotherapeutic agents-induced apoptosis in leukemic cells.
    Biochemical and biophysical research communications, 2009, May-08, Volume: 382, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Aspartic Acid; Camptothecin; Caspase 3; Caspase Inhibitors; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Etoposide; Humans; Leukemia; Mutagenesis, Site-Directed; Oligopeptides; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering; Trans-Activators

2009
siRNA-mediated down-regulation of iASPP promotes apoptosis induced by etoposide and daunorubicin in leukemia cells expressing wild-type p53.
    Leukemia research, 2009, Volume: 33, Issue:9

    Topics: Antineoplastic Agents; Apoptosis; Base Sequence; Cell Division; Cell Line, Tumor; Daunorubicin; DNA Primers; Down-Regulation; Etoposide; Humans; Intracellular Signaling Peptides and Proteins; Leukemia; Repressor Proteins; RNA, Messenger; RNA, Small Interfering; Tumor Suppressor Protein p53

2009
Nuclear translocation of dihydrofolate reductase is not a pre-requisite for DNA damage induced apoptosis.
    Apoptosis : an international journal on programmed cell death, 2009, Volume: 14, Issue:5

    Topics: Amino Acid Sequence; Apoptosis; Camptothecin; Caspase 3; Cell Line, Tumor; Cell Nucleus; DNA Damage; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Enzyme Activation; Etoposide; Humans; Leukemia; Methotrexate; Microtubules; Molecular Sequence Data; Neoplasm Proteins; Protein Transport; Tetrahydrofolate Dehydrogenase

2009
Reversal effect of PI3-K inhibitor LY294002 on P-glycoprotein-mediated multidrug resistance of human leukemia cell line K562/DNR and gastric cancer cell line SGC7901/ADR.
    Ai zheng = Aizheng = Chinese journal of cancer, 2009, Volume: 28, Issue:2

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromones; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Humans; K562 Cells; Leukemia; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Stomach Neoplasms; Vincristine

2009
Protein kinase Cdelta stimulates proteasome-dependent degradation of C/EBPalpha during apoptosis induction of leukemic cells.
    PloS one, 2009, Aug-07, Volume: 4, Issue:8

    Topics: Apoptosis; Base Sequence; Blotting, Western; Caspase 3; CCAAT-Enhancer-Binding Protein-alpha; Cell Line, Tumor; DNA Primers; Down-Regulation; Etoposide; Gene Silencing; Humans; Hydrolysis; Leukemia; Proteasome Endopeptidase Complex; Protein Kinase C-delta; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Transcription, Genetic; Ubiquitination

2009
BCR/ABL downregulates DNA-PK(CS)-dependent and upregulates backup non-homologous end joining in leukemic cells.
    Molecular biology reports, 2010, Volume: 37, Issue:5

    Topics: Androstadienes; Cell Line, Tumor; Cell Survival; Comet Assay; DNA Breaks, Double-Stranded; DNA Repair; DNA-Activated Protein Kinase; Down-Regulation; Etoposide; Fusion Proteins, bcr-abl; Humans; Leukemia; Nuclear Proteins; Piperazines; Recombination, Genetic; Time Factors; Up-Regulation; Wortmannin

2010
A comparative study of outcomes of idarubicin- and etoposide-intensified conditioning regimens for allogeneic peripheral blood stem cell transplantation in patients with high-risk acute leukemia.
    Acta pharmacologica Sinica, 2009, Volume: 30, Issue:10

    Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Aspergillus; Busulfan; China; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Disease-Free Survival; Etoposide; Female; Graft Survival; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; Idarubicin; Immunosuppressive Agents; Leukemia; Leukemia, Myeloid, Acute; Male; Methylprednisolone; Mucositis; Pneumonia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Premedication; Retrospective Studies; Risk Factors; Semustine; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Whole-Body Irradiation

2009
The cytotoxic effects of gemtuzumab ozogamicin (mylotarg) in combination with conventional antileukemic agents by isobologram analysis in vitro.
    Anticancer research, 2009, Volume: 29, Issue:11

    Topics: Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Etoposide; Gemtuzumab; HL-60 Cells; Humans; Idarubicin; Immunotoxins; Leukemia; Mercaptopurine; Methotrexate; Mitoxantrone; Sialic Acid Binding Ig-like Lectin 3; U937 Cells; Vincristine

2009
Etoposide induces more severe mucositis than CY when added to TBI as conditioning in allograft recipients receiving CsA and MTX.
    Bone marrow transplantation, 2010, Volume: 45, Issue:9

    Topics: Adolescent; Adult; Antineoplastic Agents, Phytogenic; Cyclophosphamide; Cyclosporine; Drug Therapy, Combination; Etoposide; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Leukemia; Male; Methotrexate; Middle Aged; Mucositis; Retrospective Studies; Severity of Illness Index; Transplantation Conditioning; Transplantation, Homologous; Whole-Body Irradiation; Young Adult

2010
Novel second mitochondria-derived activator of caspases (Smac) mimetic compounds sensitize human leukemic cell lines to conventional chemotherapeutic drug-induced and death receptor-mediated apoptosis.
    Investigational new drugs, 2011, Volume: 29, Issue:6

    Topics: Antigens, CD34; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cytarabine; Drug Synergism; Etoposide; Humans; Inhibitor of Apoptosis Proteins; Intracellular Signaling Peptides and Proteins; Leukemia; Mitochondrial Proteins; Protein Binding; Stem Cells; TNF-Related Apoptosis-Inducing Ligand; X-Linked Inhibitor of Apoptosis Protein

2011
Adhesion-induced drug resistance in leukemia stem cells.
    Pharmacology, 2010, Volume: 86, Issue:2

    Topics: Antineoplastic Agents; Bone Marrow Cells; Cell Adhesion; Cell Cycle; Cell Line, Tumor; Coculture Techniques; Cyclin-Dependent Kinase Inhibitor Proteins; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Etoposide; Humans; Leukemia; Lysosomes; Neoplastic Stem Cells; Osmolar Concentration; Proto-Oncogene Proteins c-bcl-2; Stem Cell Niche; Stromal Cells; Up-Regulation; Vacuolar Proton-Translocating ATPases

2010
Vandetanib mediates anti-leukemia activity by multiple mechanisms and interacts synergistically with DNA damaging agents.
    Investigational new drugs, 2012, Volume: 30, Issue:2

    Topics: Acute Disease; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers, Tumor; Cell Cycle; Cell Proliferation; Cell Survival; DNA Damage; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Etoposide; HL-60 Cells; Humans; Inhibitory Concentration 50; Leukemia; Methotrexate; Piperidines; Protein Kinase Inhibitors; Quinazolines; Topoisomerase II Inhibitors

2012
Cell cycle-dependent priming action of granulocyte colony-stimulating factor (G-CSF) enhances in vitro apoptosis induction by cytarabine and etoposide in leukemia cell lines.
    Journal of clinical and experimental hematopathology : JCEH, 2010, Volume: 50, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cytarabine; Etoposide; Flow Cytometry; Granulocyte Colony-Stimulating Factor; Humans; In Vitro Techniques; Leukemia

2010
Etoposide plus G-CSF priming compared with G-CSF alone in patients with lymphoma improves mobilization without an increased risk of secondary myelodysplasia and leukemia.
    Bone marrow transplantation, 2012, Volume: 47, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Phytogenic; Etoposide; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Lymphoma; Middle Aged; Myelodysplastic Syndromes; Neoplasms, Second Primary; Risk Factors; Young Adult

2012
In vitro synergism between LFA-1 targeting leukotoxin (Leukothera™) and standard chemotherapeutic agents in leukemia cells.
    Leukemia research, 2011, Volume: 35, Issue:11

    Topics: Adenosine Triphosphate; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzamides; Busulfan; Cell Line, Tumor; Daunorubicin; Drug Interactions; Drug Synergism; Etoposide; Exotoxins; Flow Cytometry; Humans; Imatinib Mesylate; Immunosuppressive Agents; Leukemia; Leukocytes; Lymphocyte Function-Associated Antigen-1; Membrane Potential, Mitochondrial; Mitoxantrone; Piperazines; Pyrimidines; Tumor Cells, Cultured

2011
Sex differences in the GSK3β-mediated survival of adherent leukemic progenitors.
    Oncogene, 2012, Feb-09, Volume: 31, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antigens, CD34; Antineoplastic Agents, Phytogenic; Blotting, Western; Cell Adhesion; Cell Survival; Cells, Cultured; Etoposide; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; GTP-Binding Proteins; Hematopoietic Stem Cells; Humans; Indoles; Interleukin-3 Receptor alpha Subunit; Leukemia; Male; Maleimides; Middle Aged; Neoplasm Proteins; Neoplastic Stem Cells; Protein Phosphatase 2; Receptors for Activated C Kinase; Receptors, Cell Surface; RNA Interference; Sex Factors; Tumor Cells, Cultured; Young Adult

2012
Cdx2 homeoprotein inhibits non-homologous end joining in colon cancer but not in leukemia cells.
    Nucleic acids research, 2012, Volume: 40, Issue:8

    Topics: Antigens, Nuclear; CDX2 Transcription Factor; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; DNA End-Joining Repair; DNA-Activated Protein Kinase; DNA-Binding Proteins; Etoposide; Homeodomain Proteins; Humans; Ku Autoantigen; Leukemia; Protein Interaction Domains and Motifs; Transcription, Genetic; Tumor Suppressor Proteins

2012
Anaphylactic reaction to etoposide phosphate.
    Pediatric blood & cancer, 2012, Volume: 59, Issue:4

    Topics: Anaphylaxis; Antineoplastic Agents; Etoposide; Female; Humans; Infant; Leukemia; Organophosphorus Compounds; Skin Neoplasms

2012
Bcl-2, Bcl-x(L), and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cells.
    Blood, 2012, Jun-14, Volume: 119, Issue:24

    Topics: Aniline Compounds; Animals; Apoptosis Regulatory Proteins; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Bcl-2-Like Protein 11; bcl-X Protein; Biphenyl Compounds; Cell Death; Cytoprotection; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Leukemia; Lymphoma; Membrane Proteins; Mice; Molecular Targeted Therapy; Mutant Proteins; Myeloid Cell Leukemia Sequence 1 Protein; Nitrophenols; Piperazines; Protein Binding; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Sulfonamides

2012
Nature and dynamics of nucleosome release from neoplastic and non-neoplastic cells.
    Anticancer research, 2012, Volume: 32, Issue:5

    Topics: Apoptosis; Blast Crisis; Cytarabine; Etoposide; Hep G2 Cells; Humans; L-Lactate Dehydrogenase; Leukemia; Neoplasms; Neutrophils; Nucleosomes; Tetradecanoylphorbol Acetate; TNF-Related Apoptosis-Inducing Ligand

2012
Effect of histone deacetylase inhibitors trichostatin A and valproic acid on etoposide-induced apoptosis in leukemia cells.
    Anticancer research, 2012, Volume: 32, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspase 3; Caspase 7; Drug Synergism; Etoposide; Histone Deacetylase Inhibitors; HL-60 Cells; Humans; Hydroxamic Acids; Leukemia; Membrane Potential, Mitochondrial; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; U937 Cells; Valproic Acid

2012
Schedule-dependent cytotoxicity of etoposide (VP-16) and cyclophosphamide in leukemia cell line K-562.
    Biological & pharmaceutical bulletin, 2012, Volume: 35, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Survival; Cyclophosphamide; Drug Administration Schedule; Etoposide; Humans; K562 Cells; Leukemia

2012
Do transcription factories and TOP2B provide a recipe for chromosome translocations in therapy-related leukemia?
    Cell cycle (Georgetown, Tex.), 2012, Sep-01, Volume: 11, Issue:17

    Topics: Anthracyclines; DNA Breaks, Double-Stranded; DNA Topoisomerases, Type II; DNA-Binding Proteins; Epirubicin; Etoposide; Humans; Leukemia; Mitoxantrone; Models, Genetic; Neoplasms, Second Primary; Poly-ADP-Ribose Binding Proteins; Translocation, Genetic

2012
Ataxia telangiectasia mutated-dependent regulation of topoisomerase II alpha expression and sensitivity to topoisomerase II inhibitor.
    Cancer science, 2013, Volume: 104, Issue:2

    Topics: Alanine; Antigens, Neoplasm; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; DNA Damage; DNA Topoisomerases, Type II; DNA-Binding Proteins; Etoposide; Histone-Lysine N-Methyltransferase; Humans; Leukemia; Mutagenesis, Site-Directed; Myeloid-Lymphoid Leukemia Protein; Phosphorylation; Poly-ADP-Ribose Binding Proteins; Protein Serine-Threonine Kinases; Serine; Topoisomerase II Inhibitors; Tumor Suppressor Proteins

2013
Exposure to low concentrations of etoposide reduces the apoptotic capability of leukaemic cell lines.
    Leukemia, 2002, Volume: 16, Issue:9

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Cell Division; Chromosome Aberrations; Cisplatin; DNA Damage; DNA, Neoplasm; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Flow Cytometry; Humans; Karyotyping; Leukemia; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Topoisomerase II Inhibitors; Tumor Cells, Cultured

2002
Limited and optimal sampling strategies for etoposide and etoposide catechol in children with leukemia.
    Journal of pharmacokinetics and pharmacodynamics, 2002, Volume: 29, Issue:2

    Topics: Analysis of Variance; Area Under Curve; Bayes Theorem; Catechols; Child; Etoposide; Humans; Leukemia; Linear Models; Metabolic Clearance Rate; Models, Biological; Monte Carlo Method; Statistics, Nonparametric

2002
The histone deacetylase inhibitor sodium butyrate induces DNA topoisomerase II alpha expression and confers hypersensitivity to etoposide in human leukemic cell lines.
    Molecular cancer therapeutics, 2001, Volume: 1, Issue:2

    Topics: Antigens, Neoplasm; Butyrates; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Neoplasm; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etoposide; Histone Deacetylase Inhibitors; Humans; Leukemia; Tumor Cells, Cultured

2001
Commentary: topoisomerases as targets in acute leukemia: I, II, I plus II or none?
    Leukemia research, 2003, Volume: 27, Issue:1

    Topics: Acute Disease; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Clinical Trials, Phase I as Topic; DNA Topoisomerases, Type I; DNA, Neoplasm; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Humans; Leukemia; Neoplasm Proteins; Remission Induction; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Topotecan; Treatment Outcome

2003
The influence of etoposide on the distribution of tubulin in human leukemia cell line HL-60.
    Medical science monitor : international medical journal of experimental and clinical research, 2003, Volume: 9, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Division; Dose-Response Relationship, Drug; Etoposide; Fluorescent Antibody Technique, Indirect; HL-60 Cells; Humans; Leukemia; Tubulin; Tumor Cells, Cultured

2003
Risk of secondary leukemia after a solid tumor in childhood according to the dose of epipodophyllotoxins and anthracyclines: a case-control study by the Société Française d'Oncologie Pédiatrique.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Mar-15, Volume: 21, Issue:6

    Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Bone Marrow; Case-Control Studies; Chemotherapy, Adjuvant; Child; Child, Preschool; Drug Administration Schedule; Etoposide; Female; France; Humans; Leukemia; Male; Multivariate Analysis; Neoplasms; Neoplasms, Second Primary; Radiotherapy, Adjuvant; Risk Assessment; Risk Factors

2003
Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activation.
    The Journal of biological chemistry, 2003, Jun-06, Volume: 278, Issue:23

    Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Binding Sites; Camptothecin; Carrier Proteins; Caspase 7; Caspases; Cell Membrane; Cricetinae; Doxorubicin; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Enzyme Precursors; Etoposide; G1 Phase; Gene Expression; Heat-Shock Proteins; Humans; Leukemia; Molecular Chaperones; Protein Structure, Tertiary; Subcellular Fractions; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Transfection; Tumor Cells, Cultured; Urinary Bladder Neoplasms

2003
DR1-like element in human topoisomerase IIalpha gene involved in enhancement of etoposide-induced apoptosis by PPARgamma ligand.
    Experimental hematology, 2003, Volume: 31, Issue:4

    Topics: Antigens, Neoplasm; Apoptosis; Chromans; DNA Topoisomerases, Type II; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Etoposide; Flow Cytometry; Gene Expression; Humans; Jurkat Cells; Leukemia; Ligands; Mutagenesis; Phosphoproteins; Promoter Regions, Genetic; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Thiazoles; Thiazolidinediones; Topoisomerase II Inhibitors; Transcription Factors; Transfection; Troglitazone; Tumor Cells, Cultured

2003
The schedule-dependent effects of etoposide in leukaemic cell lines: a function of concentration and duration.
    Cancer chemotherapy and pharmacology, 2003, Volume: 51, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Humans; Leukemia; Time Factors; Tumor Cells, Cultured

2003
Induction of complete remission of hypoplastic leukemia with antithymocyte globulin.
    International journal of hematology, 2003, Volume: 77, Issue:3

    Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Apoptosis; Bone Marrow Examination; Cyclosporine; Diagnosis, Differential; Etoposide; Humans; Leukemia; Male; Pancytopenia; Recurrence; Remission Induction

2003
[Enhanced apoptosis-inducing effect of etoposide on leukemic cell lines M-07e and TF-1 by the proteasome inhibitor Z-LLL-CHO].
    Zhongguo shi yan xue ye xue za zhi, 2003, Volume: 11, Issue:5

    Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Cysteine Endopeptidases; Etoposide; Humans; Leukemia; Multienzyme Complexes; Oligopeptides; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-bcl-2

2003
Dual role of NF-kappaB in apoptosis of THP-1 cells during treatment with etoposide and lipopolysaccharide.
    Leukemia research, 2004, Volume: 28, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Caspase Inhibitors; Caspases; Cycloheximide; Dactinomycin; Drug Therapy, Combination; Enzyme Inhibitors; Etoposide; Humans; Inhibitor of Apoptosis Proteins; Leukemia; Lipopolysaccharides; NF-kappa B; Protein Synthesis Inhibitors; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tosyllysine Chloromethyl Ketone; Tumor Cells, Cultured; X-Linked Inhibitor of Apoptosis Protein

2004
Etoposide induces chimeric Mll gene fusions.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Artificial Gene Fusion; DNA-Binding Proteins; Enzyme Inhibitors; Etoposide; Histone-Lysine N-Methyltransferase; Humans; Leukemia; Mice; Myeloid-Lymphoid Leukemia Protein; Oncogene Proteins, Fusion; Proto-Oncogenes; Topoisomerase II Inhibitors; Transcription Factors

2004
Increased calcium influx and ribosomal content correlate with resistance to endoplasmic reticulum stress-induced cell death in mutant leukemia cell lines.
    The Journal of biological chemistry, 2004, Feb-20, Volume: 279, Issue:8

    Topics: Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Area Under Curve; Calcium; Cell Death; Cell Line, Tumor; Cycloheximide; Dithiothreitol; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Econazole; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Etoposide; Fas Ligand Protein; Flow Cytometry; HL-60 Cells; Humans; Leukemia; Membrane Glycoproteins; Oligonucleotide Array Sequence Analysis; Phenotype; Ribosomes; Thapsigargin; Time Factors; Tunicamycin

2004
[Synergistic effect of Apo2L and chemotherapeutic agents on leukemia cells].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2003, Volume: 24, Issue:11

    Topics: Antineoplastic Agents; Apoptosis Regulatory Proteins; Cytarabine; Drug Synergism; Etoposide; Female; HL-60 Cells; Humans; Leukemia; Male; Membrane Glycoproteins; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha

2003
Recombination at chromosomal sequences involved in leukaemogenic rearrangements is differentially regulated by p53.
    Carcinogenesis, 2004, Volume: 25, Issue:8

    Topics: Animals; Baculoviridae; Cell Line; Chromosomes; Cloning, Molecular; COS Cells; DNA; Down-Regulation; Enzyme Inhibitors; Etoposide; Gene Deletion; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; Leukemia; Models, Genetic; Mutation; Phenotype; Receptors, Retinoic Acid; Recombination, Genetic; Retinoic Acid Receptor alpha; Time Factors; Translocation, Genetic; Tumor Suppressor Protein p53

2004
Tailored therapy of adult acute leukaemia in Jehovah's Witnesses: unjustified reluctance to treat.
    European journal of haematology, 2004, Volume: 72, Issue:4

    Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Case Management; Cytarabine; Daunorubicin; Etoposide; Female; Hemoglobins; Hemorrhage; Humans; Jehovah's Witnesses; Leukemia; Male; Middle Aged; Multiple Organ Failure; Patient Acceptance of Health Care; Refusal to Treat; Remission Induction; Tretinoin; Vincristine

2004
Decreased nucleotide excision repair activity and alterations of topoisomerase IIalpha are associated with the in vivo resistance of a P388 leukemia subline to F11782, a novel catalytic inhibitor of topoisomerases I and II.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, May-01, Volume: 10, Issue:9

    Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents; Blotting, Northern; Catalysis; Cell Line, Tumor; Cisplatin; DNA Repair; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA-Binding Proteins; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Leukemia; Mice; Mice, Inbred DBA; Mutation, Missense; Naphthalenes; Neoplasm Transplantation; Neoplasms, Experimental; Organophosphorus Compounds; Pyrans; RNA, Messenger; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

2004
Selective induction of apoptosis by the pyrrolo-1,5-benzoxazepine 7-[[dimethylcarbamoyl]oxy]-6-(2-naphthyl)pyrrolo-[2,1-d] (1,5)-benzoxazepine (PBOX-6) in Leukemia cells occurs via the c-Jun NH2-terminal kinase-dependent phosphorylation and inactivation o
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 310, Issue:3

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Carbazoles; Dactinomycin; Drug Resistance, Neoplasm; Etoposide; Humans; Indoles; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; K562 Cells; Leukemia; Leukocytes, Mononuclear; Mitogen-Activated Protein Kinases; Oxazepines; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Subcellular Fractions; Tumor Cells, Cultured; Ultraviolet Rays

2004
Secondary leukemias in refractory germ cell tumor patients undergoing autologous stem-cell transplantation using high-dose etoposide.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Jun-01, Volume: 22, Issue:11

    Topics: Adolescent; Adult; Antineoplastic Agents, Phytogenic; Carboplatin; Combined Modality Therapy; Etoposide; Germinoma; Humans; Incidence; Indiana; Leukemia; Male; Middle Aged; Prostatic Neoplasms; Retrospective Studies; Salvage Therapy; Stem Cell Transplantation; Transplantation, Autologous

2004
Identification of deficient mitochondrial signaling in apoptosis resistant leukemia cells by flow cytometric analysis of intracellular cytochrome c, caspase-3 and apoptosis.
    Apoptosis : an international journal on programmed cell death, 2004, Volume: 9, Issue:4

    Topics: Antibodies, Monoclonal; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Membrane Permeability; Cyclophosphamide; Cytochromes c; Drug Resistance, Neoplasm; Etoposide; fas Receptor; Flow Cytometry; Humans; Jurkat Cells; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Microscopy, Fluorescence; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Transfection

2004
In vitro and in vivo evaluation of the influence of type III NaPi co-transporter activity during apoptosis on 99mTc-(V)DMSA uptake in the human leukaemic cell line U937.
    European journal of nuclear medicine and molecular imaging, 2004, Volume: 31, Issue:10

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Dose-Response Relationship, Drug; Etoposide; Humans; Leukemia; Metabolic Clearance Rate; Mice; Mice, Nude; Organ Specificity; Radionuclide Imaging; Radiopharmaceuticals; Sodium-Phosphate Cotransporter Proteins; Symporters; Technetium Tc 99m Dimercaptosuccinic Acid; Tissue Distribution

2004
Transcriptional and post-transcriptional regulation of the PKC delta gene by etoposide in L1210 murine leukemia cells: implication of PKC delta autoregulation.
    Journal of molecular biology, 2004, Jul-16, Volume: 340, Issue:4

    Topics: Acetophenones; Adenoviridae; Animals; Antineoplastic Agents; Benzopyrans; Blotting, Western; Cell Fractionation; Cell Line, Tumor; Enzyme Inhibitors; Etoposide; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Leukemic; Leukemia; Mice; Models, Biological; Protein Kinase C; Protein Kinase C-delta; RNA, Messenger; Transcription, Genetic; Up-Regulation

2004
Novel 2'-substituted, 3'-deoxy-phosphatidyl-myo-inositol analogues reduce drug resistance in human leukaemia cell lines with an activated phosphoinositide 3-kinase/Akt pathway.
    British journal of haematology, 2004, Volume: 126, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Cell Survival; Cytarabine; Down-Regulation; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Humans; Leukemia; Neoplasm Proteins; Phosphatidylinositol 3-Kinases; Phosphatidylinositols; Phosphoinositide-3 Kinase Inhibitors; Phospholipid Ethers; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Tumor Cells, Cultured

2004
PI-3-kinase/NF-kappaB mediated response of Jurkat T leukemic cells to two different chemotherapeutic drugs, etoposide and TRAIL.
    Journal of cellular biochemistry, 2004, Oct-01, Volume: 93, Issue:2

    Topics: Antineoplastic Agents; Apoptosis Regulatory Proteins; Caspase 3; Caspases; Cell Death; Enzyme Activation; Etoposide; Flow Cytometry; Gene Expression Regulation; Humans; I-kappa B Kinase; Immunohistochemistry; Jurkat Cells; Leukemia; Membrane Glycoproteins; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; TNF-Related Apoptosis-Inducing Ligand; Transcription Factor RelA; Tumor Necrosis Factor-alpha

2004
[GM-CSF regulates the Vp16 induced leukemic cell apoptosis].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 1997, Volume: 18, Issue:6

    Topics: Apoptosis; Etoposide; Flow Cytometry; Granulocyte-Macrophage Colony-Stimulating Factor; HL-60 Cells; Humans; Leukemia

1997
Camptothecin- and etoposide-induced apoptosis in human leukemia cells is independent of cell death receptor-3 and -4 aggregation but accelerates tumor necrosis factor-related apoptosis-inducing ligand-mediated cell death.
    Molecular cancer therapeutics, 2004, Volume: 3, Issue:12

    Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Camptothecin; CASP8 and FADD-Like Apoptosis Regulating Protein; Etoposide; Fas-Associated Death Domain Protein; Gene Deletion; Genes, Dominant; HL-60 Cells; Humans; Intracellular Signaling Peptides and Proteins; Leukemia; Ligands; Membrane Glycoproteins; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Member 25; TNF-Related Apoptosis-Inducing Ligand; Transfection; Tumor Necrosis Factor Ligand Superfamily Member 15; Tumor Necrosis Factor Receptor-Associated Peptides and Proteins; Tumor Necrosis Factor-alpha; TWEAK Receptor; U937 Cells

2004
Hematopoietic cytokines enhance Chk1-dependent G2/M checkpoint activation by etoposide through the Akt/GSK3 pathway to inhibit apoptosis.
    Oncogene, 2005, Mar-17, Volume: 24, Issue:12

    Topics: Animals; Apoptosis; Cell Cycle; Cell Division; Cell Line; Cell Line, Tumor; Checkpoint Kinase 1; Cytokines; Erythropoietin; Etoposide; Flow Cytometry; G2 Phase; Glycogen Synthase Kinase 3; Humans; Interleukin-3; Leukemia; Mice; Phosphorylation; Phosphotyrosine; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt

2005
p21 (Waf1/Cip1) and FasL gene activation via Sp1 and NFkappaB is required for leukemia cell survival but not for cell death induced by diverse stimuli.
    The international journal of biochemistry & cell biology, 2005, Volume: 37, Issue:4

    Topics: Apoptosis; Base Sequence; Binding Sites; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; DNA Primers; Etoposide; Fas Ligand Protein; Humans; Leukemia; Membrane Glycoproteins; NF-kappa B; Promoter Regions, Genetic; Sp1 Transcription Factor

2005
High cumulative rate of secondary leukemia after continuous etoposide treatment for solid tumors in children and young adults.
    Pediatric blood & cancer, 2005, Volume: 45, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Phytogenic; Case-Control Studies; Child; Child, Preschool; Drug Administration Schedule; Etoposide; Female; Follow-Up Studies; France; Humans; Incidence; Infant; Leukemia; Male; Neoplasms; Neoplasms, Second Primary; Palliative Care; Survival Rate

2005
Knee arthritis as a rare inaugural manifestation of adult leukemia.
    Rheumatology international, 2005, Volume: 25, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Arthritis; Cytarabine; Diagnosis, Differential; Dose-Response Relationship, Drug; Etoposide; Humans; Knee Joint; Leukemia; Magnetic Resonance Imaging; Male; Mitoxantrone; Radiography; Remission Induction; Treatment Outcome

2005
Deguelin, A PI3K/AKT inhibitor, enhances chemosensitivity of leukaemia cells with an active PI3K/AKT pathway.
    British journal of haematology, 2005, Volume: 129, Issue:5

    Topics: Acute Disease; Antigens, CD34; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cells, Cultured; Cytarabine; Drug Resistance, Neoplasm; Erythropoietin; Etoposide; HL-60 Cells; Humans; Leukemia; Leukemia, Myeloid; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Rotenone; Signal Transduction; Stem Cell Factor; Stem Cells

2005
Highly active antiretroviral therapy and outcome of AIDS-related Burkitt's lymphoma or leukemia. Results of the PETHEMA-LAL3/97 study.
    Haematologica, 2005, Volume: 90, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Antiretroviral Therapy, Highly Active; Cyclophosphamide; Cytarabine; Dexamethasone; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; Humans; Ifosfamide; Leucovorin; Leukemia; Lymphoma, AIDS-Related; Male; Methotrexate; Middle Aged; Prednisone; Treatment Outcome; Vincristine

2005
Adenovirus-mediated human topoisomerase IIalpha gene transfer increases the sensitivity of etoposide-resistant human and mouse breast cancer cells.
    Acta oncologica (Stockholm, Sweden), 2005, Volume: 44, Issue:3

    Topics: Adenoviridae; Animals; Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Resistance, Neoplasm; Etoposide; Female; Gene Expression Regulation, Enzymologic; Gene Transfer Techniques; Genetic Vectors; Humans; Isoenzymes; Leukemia; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; RNA, Messenger; Transduction, Genetic; Tumor Burden

2005
Usefulness of PKH fluorescent labelling to study leukemic cell proliferation with various cytostatic drugs or acetyl tetrapeptide--AcSDKP.
    BMC cancer, 2005, Sep-20, Volume: 5

    Topics: Amsacrine; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Bromodeoxyuridine; Cell Proliferation; Cytarabine; Daunorubicin; DNA; Etoposide; Flow Cytometry; Fluorescent Dyes; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydrocarbons, Chlorinated; Leukemia; Leukemia, Myeloid, Acute; Microscopy, Fluorescence; Oligopeptides; Organic Chemicals; Radiation-Protective Agents

2005
MLL rearrangements are induced by low doses of etoposide in human fetal hematopoietic stem cells.
    Carcinogenesis, 2006, Volume: 27, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Cell Culture Techniques; Cell Cycle; Cell Survival; DNA Damage; Dose-Response Relationship, Drug; Etoposide; Female; Fetus; Gene Rearrangement; Hematopoietic Stem Cells; Histone-Lysine N-Methyltransferase; Humans; Leukemia; Maternal-Fetal Exchange; Myeloid-Lymphoid Leukemia Protein; Pregnancy

2006
Influence of galangin on HL-60 cell proliferation and survival.
    Cancer letters, 2006, Nov-08, Volume: 243, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Caspase 3; Cell Cycle; Cell Differentiation; Cell Membrane; Cell Proliferation; Cell Size; Cell Survival; Dimethyl Sulfoxide; DNA Fragmentation; DNA, Neoplasm; Dose-Response Relationship, Drug; Etoposide; Flavonoids; Flow Cytometry; HL-60 Cells; Humans; Leukemia; Mutagens; Nucleosomes; Phosphatidylserines; Reactive Oxygen Species

2006
Early stem cell transplantation for refractory acute leukemia after salvage therapy with high-dose etoposide and cyclophosphamide.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2006, Volume: 12, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Cyclophosphamide; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; Humans; Leukemia; Male; Middle Aged; Remission Induction; Retrospective Studies; Salvage Therapy; Stem Cell Transplantation; Survival Rate

2006
Antileukemic roles of human phospholipid scramblase 1 gene, evidence from inducible PLSCR1-expressing leukemic cells.
    Oncogene, 2006, Oct-26, Volume: 25, Issue:50

    Topics: Apoptosis; Cell Cycle; Cell Differentiation; Cell Line; Cell Proliferation; Etoposide; G1 Phase; Gene Expression Regulation; Gene Expression Regulation, Leukemic; Humans; Leukemia; Myeloid Cells; Phospholipid Transfer Proteins; Transfection; Tumor Cells, Cultured; U937 Cells

2006
[Influence of chemotherapy on expression of TRAIL in primary acute leukemic cells].
    Zhongguo shi yan xue ye xue za zhi, 2006, Volume: 14, Issue:3

    Topics: Acute Disease; Antineoplastic Agents; Bone Marrow Cells; Etoposide; Humans; Interferon-alpha; Leukemia; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured

2006
Cytotoxic effects of histone deacetylase inhibitor FK228 (depsipeptide, formally named FR901228) in combination with conventional anti-leukemia/lymphoma agents against human leukemia/lymphoma cell lines.
    Investigational new drugs, 2007, Volume: 25, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Benzamides; Camptothecin; Carboplatin; Cell Line, Tumor; Cell Survival; Cyclophosphamide; Cytarabine; Depsipeptides; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Etoposide; Histone Deacetylase Inhibitors; HL-60 Cells; Humans; Imatinib Mesylate; Irinotecan; K562 Cells; Leukemia; Lymphoma; Mercaptopurine; Piperazines; Pyrimidines; Time Factors

2007
Zygomycosis in the immunocompromised patient: a case report.
    Acta bio-medica : Atenei Parmensis, 2006, Volume: 77 Suppl 2

    Topics: Absidia; Acute Disease; Aerosols; Amphotericin B; Amsacrine; Antibiotic Prophylaxis; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Daunorubicin; Debridement; Drug Resistance, Fungal; Drug Resistance, Neoplasm; Etoposide; Fluconazole; Humans; Immunocompromised Host; Leukemia; Liposomes; Middle Aged; Mucormycosis; Sinusitis; Tomography, X-Ray Computed

2006
Overexpression of sorcin in multidrug resistant human leukemia cells and its role in regulating cell apoptosis.
    Biochemical and biophysical research communications, 2006, Oct-13, Volume: 349, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Calcium-Binding Proteins; Cell Line, Tumor; Cytosol; Electrophoresis, Gel, Two-Dimensional; Etoposide; Gene Expression Regulation, Neoplastic; Humans; K562 Cells; Leukemia; Proteomics; Proto-Oncogene Proteins c-bcl-2

2006
Chemotherapy-related secondary leukemias: A role for DNA repair by error-prone non-homologous end joining in topoisomerase II - Induced chromosomal rearrangements.
    Gene, 2007, Apr-15, Volume: 391, Issue:1-2

    Topics: Antineoplastic Agents, Phytogenic; Chromatin Immunoprecipitation; Chromosome Aberrations; Chromosome Breakage; Core Binding Factor Alpha 2 Subunit; DNA Breaks, Double-Stranded; DNA Repair; DNA Topoisomerases, Type II; Drug-Related Side Effects and Adverse Reactions; Etoposide; Humans; Jurkat Cells; Leukemia; Neoplasms; Protein Binding; Rad52 DNA Repair and Recombination Protein; Recombination, Genetic; Topoisomerase II Inhibitors

2007
Divergent cytotoxic effects of PKC412 in combination with conventional antileukemic agents in FLT3 mutation-positive versus -negative leukemia cell lines.
    Leukemia, 2007, Volume: 21, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Cell Line, Tumor; Cytarabine; Doxorubicin; Etoposide; fms-Like Tyrosine Kinase 3; Humans; Idarubicin; Leukemia; Methotrexate; Mitoxantrone; Mutation; Protein Kinase C; Staurosporine

2007
Synergism between etoposide and 17-AAG in leukemia cells: critical roles for Hsp90, FLT3, topoisomerase II, Chk1, and Rad51.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Mar-01, Volume: 13, Issue:5

    Topics: Antineoplastic Agents; Benzoquinones; Blotting, Western; Cell Line, Tumor; Checkpoint Kinase 1; DNA Repair Enzymes; DNA Topoisomerases, Type II; Drug Synergism; Etoposide; fms-Like Tyrosine Kinase 3; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Leukemia; Protein Kinases; Rad51 Recombinase; RNA, Small Interfering

2007
CODOX-M/IVAC (NCI 89-C-41) in children and adolescents with Burkitt's leukemia/lymphoma and large B-cell lymphomas: a 15-year monocentric experience.
    Leukemia & lymphoma, 2007, Volume: 48, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Leukemia; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Risk Factors; Survival Rate; Treatment Outcome; Vincristine

2007
Dietary flavonoids induce MLL translocations in primary human CD34+ cells.
    Carcinogenesis, 2007, Volume: 28, Issue:8

    Topics: Antigens, CD34; Cells, Cultured; Dietary Supplements; DNA Breaks, Double-Stranded; Etoposide; Flavonoids; Genistein; Histone-Lysine N-Methyltransferase; Humans; Kaempferols; Leukemia; Leukocytes, Mononuclear; Myeloid-Lymphoid Leukemia Protein; Quercetin; Translocation, Genetic

2007
The role of cordycepin in cancer treatment via induction or inhibition of apoptosis: implication of polyadenylation in a cell type specific manner.
    Cancer chemotherapy and pharmacology, 2008, Volume: 61, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Caspase 6; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Deoxyadenosines; DNA Fragmentation; Etoposide; Flow Cytometry; Fluorescent Dyes; Humans; Image Processing, Computer-Assisted; Indoles; Leukemia; Membrane Potentials; Mitochondrial Membranes; Neoplasms; Poly A

2008
Genome scan implicates adhesion biological pathways in secondary leukemia.
    Leukemia, 2007, Volume: 21, Issue:10

    Topics: Adolescent; Case-Control Studies; Cell Adhesion; Child; Child, Preschool; Cohort Studies; Etoposide; Female; Gene Frequency; Genome, Human; Humans; Infant; Leukemia; Loss of Heterozygosity; Male; Polymorphism, Single Nucleotide; Translocation, Genetic

2007
Long-term follow-up of busulfan, etoposide, and nimustine hydrochloride (ACNU) or melphalan as conditioning regimens for childhood acute leukemia and lymphoma.
    International journal of hematology, 2007, Volume: 86, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Child, Preschool; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; Humans; Infant; Leukemia; Lymphoma; Lymphoma, Non-Hodgkin; Male; Melphalan; Nimustine; Recurrence; Retrospective Studies; Stem Cell Transplantation; Survival Rate; Transplantation Conditioning; Transplantation, Homologous

2007
Genotoxic stress-induced expression of p53 and apoptosis in leukemic clam hemocytes with cytoplasmically sequestered p53.
    Cancer research, 2008, Feb-01, Volume: 68, Issue:3

    Topics: Amino Acid Sequence; Animals; Apoptosis; DNA Damage; Etoposide; Fatty Acids, Unsaturated; Hemocytes; Humans; Leukemia; Mitoxantrone; Molecular Sequence Data; Mya; Topoisomerase II Inhibitors; Tumor Suppressor Protein p53

2008
Ornithine decarboxylase attenuates leukemic chemotherapy drugs-induced cell apoptosis and arrest in human promyelocytic HL-60 cells.
    Leukemia research, 2008, Volume: 32, Issue:10

    Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Caspases; Cell Cycle; Cisplatin; Etoposide; Glutathione; HL-60 Cells; Humans; Leukemia; Membrane Potential, Mitochondrial; Ornithine Decarboxylase; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; Putrescine; Reactive Oxygen Species

2008
Clinical and cell kinetic studies of the effects of the epipodophyllotoxin VP16-213 during therapy of refractory acute nonlymphocytic leukemia.
    Cancer chemotherapy and pharmacology, 1982, Volume: 7, Issue:2-3

    Topics: Acute Disease; Adolescent; Adult; Azacitidine; Cell Division; Child; Child, Preschool; DNA, Neoplasm; Drug Resistance; Etoposide; Female; Flow Cytometry; Humans; Infant; Kinetics; Leukemia; Male; Mitosis; Podophyllotoxin

1982
Single-agent and combination chemotherapy with etoposide in the acute leukemias of childhood.
    Cancer treatment reviews, 1982, Volume: 9 Suppl

    Topics: Acute Disease; Azacitidine; Child; Drug Therapy, Combination; Etoposide; Humans; Leukemia; Podophyllotoxin; Prednisone; Vincristine

1982
Pharmacokinetics of etoposide (VP16) in children and adolescents with refractory solid tumors.
    Cancer research, 1984, Volume: 44, Issue:7

    Topics: Adolescent; Adult; Child; Child, Preschool; Cisplatin; Etoposide; Female; Humans; Kinetics; Leukemia; Male; Metabolic Clearance Rate; Neoplasms; Podophyllotoxin

1984
[VP 16-213 in the treatment of acute leukemia in childhood].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:3

    Topics: Acute Disease; Adolescent; Antineoplastic Agents; Child; Child, Preschool; Cytarabine; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Leukemia; Leukemia, Lymphoid; Male; Podophyllotoxin

1983
Pharmacokinetics of Teniposide (VM26) and etoposide (VP16-213) in children with cancer.
    Cancer chemotherapy and pharmacology, 1982, Volume: 7, Issue:2-3

    Topics: Biotransformation; Child; Chromatography, High Pressure Liquid; Etoposide; Humans; Kinetics; Leukemia; Models, Biological; Neoplasms; Podophyllotoxin; Teniposide

1982
Etoposide in the treatment of acute leukemia in adults.
    Cancer treatment reviews, 1982, Volume: 9 Suppl

    Topics: Acute Disease; Adult; Drug Administration Schedule; Drug Therapy, Combination; Etoposide; Humans; Leukemia; Podophyllotoxin

1982
Hypophosphorylation of topoisomerase II in etoposide (VP-16)-resistant human leukemia K562 cells associated with reduced levels of beta II protein kinase C.
    Molecular pharmacology, 1995, Volume: 48, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; DNA; DNA Damage; DNA Topoisomerases, Type II; Drug Resistance; Etoposide; Humans; Leukemia; Phosphorylation; Protein Kinase C; Tumor Cells, Cultured

1995
Evaluation of the cytotoxic activity of gemcitabine in primary cultures of tumor cells from patients with hematologic or solid tumors.
    Seminars in oncology, 1995, Volume: 22, Issue:4 Suppl 11

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Cisplatin; Cladribine; Colorectal Neoplasms; Cytarabine; Deoxycytidine; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Female; Gemcitabine; Humans; In Vitro Techniques; Leukemia; Lung Neoplasms; Lymphoma; Ribonucleotide Reductases; Tumor Cells, Cultured; Urogenital Neoplasms

1995
[Successful collection of peripheral blood stem cells mobilized by a combination of G-CSF with high-dose Ara-C or high-dose etoposide].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1993, Volume: 34, Issue:12

    Topics: Acute Disease; Adolescent; Adult; Blood Component Removal; Cytarabine; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Lymphoma, Non-Hodgkin; Male; Middle Aged

1993
A new flow cytometric method for discrimination of apoptotic cells and detection of their cell cycle specificity through staining of F-actin and DNA.
    Cytometry, 1995, Jun-01, Volume: 20, Issue:2

    Topics: Actins; Apoptosis; Cell Cycle; Cycloheximide; Dactinomycin; DNA, Neoplasm; Etoposide; Evaluation Studies as Topic; Flow Cytometry; Humans; Leukemia; Microscopy, Confocal; Phalloidine; Propidium; Staining and Labeling; Tumor Cells, Cultured

1995
Further characterisation of the in situ terminal deoxynucleotidyl transferase (TdT) assay for the flow cytometric analysis of apoptosis in drug resistant and drug sensitive leukaemic cells.
    Cytometry, 1995, Jul-01, Volume: 20, Issue:3

    Topics: Abelson murine leukemia virus; Antineoplastic Agents; Apoptosis; Cell Nucleus; DNA Damage; DNA Nucleotidylexotransferase; DNA, Neoplasm; Drug Resistance, Neoplasm; Etoposide; Flow Cytometry; HL-60 Cells; Humans; Hydroxyurea; Leukemia; Melphalan; Oncogene Proteins v-abl; Protein-Tyrosine Kinases; Recombinant Proteins; Tumor Cells, Cultured

1995
The role of cell cycle regulation and apoptosis triggering in determining the sensitivity of leukemic cells to topoisomerase I and II inhibitors.
    Leukemia, 1995, Volume: 9, Issue:6

    Topics: Apoptosis; Base Sequence; Camptothecin; Cell Cycle; Cell Line; Cell Survival; DNA Damage; DNA Primers; DNA, Neoplasm; Dose-Response Relationship, Drug; Etoposide; Humans; Leukemia; Microscopy, Electron; Molecular Sequence Data; Polymerase Chain Reaction; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1995
Extramedullary toxicity of a conditioning regimen containing busulphan, cyclophosphamide and etoposide in 84 patients undergoing autologous and allogenic bone marrow transplantation.
    Bone marrow transplantation, 1995, Volume: 15, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Marrow Transplantation; Busulfan; Combined Modality Therapy; Cyclophosphamide; Etoposide; Female; Graft vs Host Disease; Humans; Leukemia; Lung; Lymphoma; Male; Middle Aged; Recurrence; Skin; Survival Rate; Transplantation, Autologous; Transplantation, Homologous

1995
Risk of secondary leukemia following high cumulative doses of etoposide during chemotherapy for testicular cancer.
    Journal of the National Cancer Institute, 1995, Jan-04, Volume: 87, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Etoposide; Humans; Leukemia; Male; Neoplasms, Second Primary; Testicular Neoplasms

1995
Secondary leukemia associated with a conventional dose of etoposide: review of serial germ cell tumor protocols.
    Journal of the National Cancer Institute, 1993, Jan-06, Volume: 85, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 4; Cisplatin; Clinical Trials as Topic; Etoposide; Humans; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Neoplasms, Germ Cell and Embryonal; Neoplasms, Second Primary; Retrospective Studies; Salvage Therapy; Testicular Neoplasms; Translocation, Genetic

1993
ALL-1 gene rearrangements in DNA topoisomerase II inhibitor-related leukemia in children.
    Blood, 1995, Jun-01, Volume: 85, Issue:11

    Topics: Acute Disease; Adolescent; Bone Marrow Transplantation; Child; Child, Preschool; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, Pair 11; Combined Modality Therapy; Dactinomycin; DNA-Binding Proteins; Etoposide; Female; Genes; Histone-Lysine N-Methyltransferase; Humans; Infant; Leukemia; Leukemia, Myeloid; Leukemia, Radiation-Induced; Male; Myelodysplastic Syndromes; Myeloid-Lymphoid Leukemia Protein; Neoplasm Proteins; Neoplasms; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogenes; Radiotherapy; Teniposide; Topoisomerase II Inhibitors; Transcription Factors; Translocation, Genetic; Whole-Body Irradiation

1995
Collection and transplantation of peripheral blood stem cells in very small children weighting 20 kg or less.
    Blood, 1995, Jul-01, Volume: 86, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Component Removal; Blood Preservation; Body Weight; Bone Marrow Diseases; Carboplatin; Catheterization, Central Venous; Catheters, Indwelling; Child, Preschool; Cisplatin; Colony-Forming Units Assay; Combined Modality Therapy; Contraindications; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Graft Survival; Hematopoietic Stem Cell Transplantation; Humans; Infant; Leukemia; Male; Neoplasms; Platelet Transfusion; Retrospective Studies; Safety

1995
[Therapeutic effects of peripheral blood stem cell transplantation following combination chemotherapy using ranimustine, cytarabine, etoposide and cyclophosphamide for patients with hematological malignancies].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Lymphoma; Male; Middle Aged; Nitrosourea Compounds

1994
Differential induction of etoposide-mediated apoptosis in human leukemia HL-60 and K562 cells.
    Molecular pharmacology, 1994, Volume: 46, Issue:4

    Topics: Apoptosis; Cell Nucleus; DNA; DNA Damage; Etoposide; Flow Cytometry; Gene Expression Regulation; Genes, fos; Genes, jun; Humans; Leukemia; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured

1994
Drug-sensitivity and DNA-binding of a subform of topoisomerase II alpha in resistant human HL-60 cells.
    Acta oncologica (Stockholm, Sweden), 1994, Volume: 33, Issue:7

    Topics: Amsacrine; Antigens, Neoplasm; Antineoplastic Agents; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Neoplasm; Drug Resistance; Etoposide; Humans; Isoenzymes; Leukemia; Tumor Cells, Cultured; Vanadates

1994
Quantification of topoisomerase-DNA complexes in leukemia cells from patients undergoing therapy with a topoisomerase-directed agent.
    Cancer chemotherapy and pharmacology, 1994, Volume: 34, Issue:3

    Topics: Amsacrine; Antineoplastic Agents; Camptothecin; DNA Probes; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA, Neoplasm; Drug Resistance; Etoposide; Humans; Immunoblotting; Leukemia; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Topotecan; Tumor Cells, Cultured

1994
Reduced phosphorylation of topoisomerase II in etoposide-resistant human leukemia K562 cells.
    Molecular pharmacology, 1994, Volume: 46, Issue:1

    Topics: Adenosine Triphosphate; Base Sequence; DNA Topoisomerases, Type II; DNA, Complementary; DNA, Neoplasm; Drug Resistance; Etoposide; Humans; Leukemia; Molecular Sequence Data; Nuclear Proteins; Phosphorylation; Polymorphism, Genetic; Sequence Analysis, DNA; Tumor Cells, Cultured

1994
Etoposide, cyclophosphamide, total-body irradiation, and allogeneic bone marrow transplantation for hematologic malignancies.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1994, Volume: 12, Issue:9

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cyclophosphamide; Etoposide; Female; Hemorrhage; Humans; Leukemia; Lung Diseases; Lymphoma; Male; Middle Aged; Recurrence; Survival Rate; Transplantation, Homologous; Whole-Body Irradiation

1994
21-day schedule oral etoposide in children--a feasibility study.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:16

    Topics: Administration, Oral; Adolescent; Child; Child, Preschool; Drug Administration Schedule; Etoposide; Feasibility Studies; Female; Humans; Leukemia; Leukopenia; Male; Neuroblastoma; Neutropenia; Sarcoma; Thrombocytopenia; Treatment Outcome

1993
[Neutropenic typhlitis: a frequently missed complication of aplasia-inducing tumor therapy with a possible association to the combination of etoposide with high-dose cytosine-arabinoside].
    Schweizerische medizinische Wochenschrift, 1994, Feb-05, Volume: 124, Issue:5

    Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Synergism; Enterocolitis, Pseudomembranous; Etoposide; Female; Humans; Leukemia; Male; Neutropenia; Retrospective Studies

1994
Tyrosinase-induced phenoxyl radicals of etoposide (VP-16): interaction with reductants in model systems, K562 leukemic cell and nuclear homogenates.
    Free radical research communications, 1993, Volume: 19, Issue:6

    Topics: Ascorbic Acid; Cell Nucleus; Chromatography, High Pressure Liquid; Deferoxamine; Electron Spin Resonance Spectroscopy; Etoposide; Free Radicals; Glutathione; Humans; Leukemia; Monophenol Monooxygenase; Oxidation-Reduction; Phenols; Thioctic Acid; Tumor Cells, Cultured

1993
Etoposide in combination with cyclophosphamide and total body irradiation or busulfan as conditioning for marrow transplantation in adults and children.
    International journal of radiation oncology, biology, physics, 1994, Apr-30, Volume: 29, Issue:1

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclophosphamide; Dose-Response Relationship, Drug; Etoposide; Female; Humans; Infant; Leukemia; Lung Diseases, Interstitial; Lymphoma; Male; Middle Aged; Retrospective Studies; Skin Diseases; Whole-Body Irradiation

1994
Altered gene expression in human leukemia K562 cells selected for resistance to etoposide.
    Biochemical pharmacology, 1993, Dec-03, Volume: 46, Issue:11

    Topics: DNA Topoisomerases, Type II; Drug Resistance; Etoposide; Gene Expression; Humans; Leukemia; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured

1993
Phorbol regulation of topoisomerases I and II in human leukemia cells. Studies in an additional cell pair sensitive or resistant to phorbol-induced differentiation.
    Biochemical pharmacology, 1994, Jan-20, Volume: 47, Issue:2

    Topics: Cell Differentiation; Cell Nucleus; Cell Survival; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Etoposide; Gene Expression Regulation, Enzymologic; Humans; Leukemia; Phorbol Esters; Tissue Extracts; Tumor Cells, Cultured

1994
Novel selection and genetic characterisation of an etoposide-resistant human leukaemic CCRF-CEM cell line.
    British journal of cancer, 1993, Volume: 67, Issue:3

    Topics: Base Sequence; Chromosome Banding; Chromosomes, Human, Pair 20; Chromosomes, Human, Pair 3; Codon; DNA Topoisomerases, Type II; DNA, Neoplasm; Drug Resistance; Etoposide; Humans; Karyotyping; Leukemia; Molecular Sequence Data; Mutation; Phenotype; Polymerase Chain Reaction; Sequence Analysis, DNA; Tumor Cells, Cultured

1993
Role of total body irradiation as based on the comparison of preparation regimens for allogeneic bone marrow transplantation for acute leukemia in first complete remission.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1993, Volume: 169, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Etoposide; Female; Humans; Infant; Japan; Leukemia; Male; Methotrexate; Nimustine; Proportional Hazards Models; Radiotherapy Dosage; Remission Induction; Transplantation, Homologous; Whole-Body Irradiation

1993
Growth and growth hormone secretion after bone marrow transplantation.
    Archives of disease in childhood, 1993, Volume: 68, Issue:4

    Topics: Bone Marrow Transplantation; Child; Child, Preschool; Clinical Protocols; Cyclophosphamide; Etoposide; Female; Growth; Growth Disorders; Growth Hormone; Humans; Infant; Insulin-Like Growth Factor I; Leukemia; Male; Melphalan; Radiotherapy Dosage; Whole-Body Irradiation

1993
Hematopoietic growth factors after HLA-identical allogeneic bone marrow transplantation in patients treated with methotrexate-containing graft-vs.-host disease prophylaxis.
    Experimental hematology, 1995, Volume: 23, Issue:14

    Topics: Adult; Aged; Bone Marrow Transplantation; Cyclophosphamide; Etoposide; Female; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Histocompatibility; Humans; Leukemia; Male; Methotrexate; Middle Aged; Recombinant Proteins; Recurrence; Survival Rate; Transplantation, Homologous; Treatment Outcome; Whole-Body Irradiation

1995
Pneumocystis carinii pneumonia in adults with acute leukaemia: is there a need for primary chemoprophylaxis?
    European journal of haematology, 1996, Volume: 56, Issue:3

    Topics: Aclarubicin; Acute Disease; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cohort Studies; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Etoposide; Female; Finland; Humans; Immunocompromised Host; Incidence; Leukemia; Male; Mercaptopurine; Methotrexate; Middle Aged; Mitoxantrone; Pneumonia, Pneumocystis; Prednisone; Premedication; Retrospective Studies; Thioguanine; Trimethoprim, Sulfamethoxazole Drug Combination; Vincristine

1996
Reversal effect of itraconazole on adriamycin and etoposide resistance in human leukemia cells.
    Annals of hematology, 1996, Volume: 72, Issue:1

    Topics: Antibiotics, Antineoplastic; Antifungal Agents; Antineoplastic Agents, Phytogenic; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Itraconazole; Leukemia; Tumor Cells, Cultured

1996
Distribution of 11q23 breakpoints within the MLL breakpoint cluster region in de novo acute leukemia and in treatment-related acute myeloid leukemia: correlation with scaffold attachment regions and topoisomerase II consensus binding sites.
    Blood, 1996, Mar-01, Volume: 87, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents, Phytogenic; Base Sequence; Binding Sites; Centromere; Child; Child, Preschool; Chromatin; Chromosomes, Human, Pair 11; Consensus Sequence; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Neoplasm; Etoposide; Female; Histone-Lysine N-Methyltransferase; Humans; Infant; Leukemia; Male; Middle Aged; Molecular Sequence Data; Myeloid-Lymphoid Leukemia Protein; Neoplasms, Second Primary; Proto-Oncogenes; Telomere; Teniposide; Topoisomerase II Inhibitors; Transcription Factors; Translocation, Genetic; Tumor Cells, Cultured

1996
[Apoptosis of human leukemic cells induced by topoisomerase I and II inhibitors].
    Bulletin du cancer, 1996, Volume: 83, Issue:3

    Topics: Alkaloids; Apoptosis; Camptothecin; Cell Cycle; Cell Differentiation; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA, Neoplasm; Etoposide; Humans; Leukemia; Protein Kinase C; Signal Transduction; Staurosporine; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1996
High-dose carmustine, etoposide and melphalan ('BEM') with autologous stem cell transplantation: a dose-toxicity study.
    Bone marrow transplantation, 1996, Volume: 17, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Combined Modality Therapy; Dose-Response Relationship, Drug; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Liver Function Tests; Lymphoma; Male; Melphalan; Middle Aged; Multiple Myeloma; Respiratory Function Tests; Retrospective Studies; Transplantation, Autologous

1996
[Effects of carboplatin combination with etoposide against leukemia/lymphoma cell lines].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Etoposide; Humans; Leukemia; Lymphoma; Tumor Cells, Cultured

1996
[Modulation of bcl-2 antisense RNA on programmed cell death of leukemic cell line].
    Zhonghua yi xue za zhi, 1996, Volume: 76, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Leukemia; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; RNA, Antisense; Tumor Cells, Cultured

1996
Collateral sensitivity to the bisdioxopiperazine dexrazoxane (ICRF-187) in etoposide (VP-16)-resistant human leukemia K562 cells.
    Biochemical pharmacology, 1996, Aug-23, Volume: 52, Issue:4

    Topics: Alkenes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etoposide; Humans; Leukemia; Polyenes; Pyrones; Razoxane; Thiobarbiturates

1996
Monoclonal antibody to single-stranded DNA is a specific and sensitive cellular marker of apoptosis.
    Experimental cell research, 1996, Aug-01, Volume: 226, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Apoptosis; Biomarkers; Cell Line; Cisplatin; DNA, Single-Stranded; Etoposide; Fluorescent Antibody Technique, Indirect; HL-60 Cells; Humans; Immunohistochemistry; Leukemia; Mice; Necrosis; Sensitivity and Specificity; Tumor Cells, Cultured

1996
[CD7, HLA-DR, CD38 positive acute undifferentiated leukemia with subcutaneous tumor and thymoma].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1996, Volume: 37, Issue:8

    Topics: Acute Disease; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antigens, CD; Antigens, CD7; Antigens, Differentiation; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Etoposide; Gene Rearrangement; HLA-DR Antigens; Humans; Immunoglobulin Heavy Chains; Immunophenotyping; Leukemia; Membrane Glycoproteins; Mitoxantrone; N-Glycosyl Hydrolases; Prednisolone; Receptors, Antigen, T-Cell, gamma-delta; Remission Induction; Skin Neoplasms; Thymoma; Thymus Neoplasms

1996
Endo-exonuclease of human leukaemic cells: evidence for a role in apoptosis.
    Journal of cell science, 1996, Volume: 109 ( Pt 9)

    Topics: Apoptosis; Cell Nucleus; Cytosol; DNA Fragmentation; Endonucleases; Endoplasmic Reticulum; Etoposide; Exonucleases; Humans; Kinetics; Leukemia; Molecular Weight; Podophyllotoxin; Tumor Cells, Cultured

1996
Influence of graft-versus-host disease on outcome following allogeneic transplantation with radiation-free preparative therapy in patients with advanced leukemia.
    Bone marrow transplantation, 1996, Volume: 18, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Combined Modality Therapy; Cyclophosphamide; Etoposide; Graft vs Host Disease; Humans; Leukemia; Treatment Outcome

1996
Relationship between cytotoxicity and site-specific DNA recombination after in vitro exposure of leukemia cells to etoposide.
    Journal of the National Cancer Institute, 1996, Dec-18, Volume: 88, Issue:24

    Topics: Acute Disease; Antineoplastic Agents, Phytogenic; Base Sequence; DNA Primers; DNA, Neoplasm; Etoposide; Exons; Gene Rearrangement; Humans; Leukemia; Leukemia, Myeloid; Molecular Sequence Data; Neoplasms, Second Primary; Sequence Deletion; Time Factors; Tumor Cells, Cultured

1996
Increased gadd153 messenger RNA level is associated with apoptosis in human leukemic cells treated with etoposide.
    Cancer research, 1997, Feb-15, Volume: 57, Issue:4

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; CCAAT-Enhancer-Binding Proteins; Daunorubicin; DNA Fragmentation; DNA-Binding Proteins; Etoposide; HL-60 Cells; Humans; Leukemia; Nuclear Proteins; RNA, Messenger; Serine Proteinase Inhibitors; Transcription Factor CHOP; Transcription Factors; Tumor Cells, Cultured

1997
Enhancement of etoposide (VP-16) cytotoxicity by enzymatic and photodynamically induced oxidative stress.
    Anti-cancer drugs, 1997, Volume: 8, Issue:2

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Buthionine Sulfoximine; Cytoplasm; DNA Damage; Drug Synergism; Electron Spin Resonance Spectroscopy; Etoposide; Free Radicals; Glutathione; Humans; Indoles; Leukemia; Organometallic Compounds; Oxidative Stress; Photosensitizing Agents; Tumor Cells, Cultured

1997
Low levels of serum soluble c-kit relates to delayed engraftment after bone marrow transplantation.
    Leukemia & lymphoma, 1997, Volume: 25, Issue:3-4

    Topics: Adolescent; Adult; Antineoplastic Agents, Phytogenic; Bone Marrow Transplantation; Cyclophosphamide; Etoposide; Graft Rejection; Graft vs Host Disease; Humans; Leukemia; Lymphoma; Proto-Oncogene Proteins c-kit; Transplantation Conditioning; Whole-Body Irradiation

1997
Autologous bone marrow purging by in situ IL-2 activation of endogenous killer cells.
    Leukemia, 1997, Volume: 11, Issue:5

    Topics: Bone Marrow Purging; Bone Marrow Transplantation; Breast Neoplasms; Colony-Forming Units Assay; Cytarabine; Cytotoxicity, Immunologic; Daunorubicin; Drug Resistance, Neoplasm; Etoposide; Female; Hematopoietic Stem Cells; HL-60 Cells; Humans; Interleukin-2; Killer Cells, Lymphokine-Activated; Killer Cells, Natural; Leukemia; Lung Neoplasms; Lymphocyte Activation; Tissue Donors; Transplantation, Autologous; Transplantation, Homologous; Tumor Cells, Cultured

1997
[Purging of hemopoietic progenitor cells in autologous transplantation].
    Casopis lekaru ceskych, 1997, Mar-12, Volume: 136, Issue:5

    Topics: Adult; Bone Marrow Purging; Child; Cyclophosphamide; Deferoxamine; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Methylprednisolone; Neuroblastoma; Transplantation, Autologous

1997
Increased MRP expression is associated with resistance to radiation, anthracyclines and etoposide in cells treated with fractionated gamma-radiation.
    International journal of cancer, 1997, Sep-26, Volume: 73, Issue:1

    Topics: Antibiotics, Antineoplastic; ATP-Binding Cassette Transporters; Dose Fractionation, Radiation; Drug Resistance; Etoposide; Gamma Rays; Humans; Leukemia; Multidrug Resistance-Associated Proteins; Radiation Tolerance; RNA, Messenger; Tumor Cells, Cultured

1997
Mechanisms of resistance in a human cell line exposed to sequential topoisomerase poisoning.
    Cancer research, 1997, Nov-15, Volume: 57, Issue:22

    Topics: Antineoplastic Agents; Camptothecin; Cell Nucleus; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Drug Resistance, Neoplasm; Etoposide; Humans; Leukemia; Phenotype; Point Mutation; RNA, Messenger; Tumor Cells, Cultured

1997
Drug-induced death of leukaemic cells after G2/M arrest: higher order DNA fragmentation as an indicator of mechanism.
    British journal of cancer, 1998, Volume: 77, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Division; Cell Size; Coloring Agents; DNA Fragmentation; DNA, Neoplasm; Electrophoresis, Gel, Pulsed-Field; Etoposide; G2 Phase; Gene Expression; Humans; Leukemia; Mitosis; Polymerase Chain Reaction; Trypan Blue; Tumor Cells, Cultured

1998
Bcr-Abl exerts its antiapoptotic effect against diverse apoptotic stimuli through blockage of mitochondrial release of cytochrome C and activation of caspase-3.
    Blood, 1998, Mar-01, Volume: 91, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Cysteine Endopeptidases; Cytarabine; Cytochrome c Group; Enzyme Activation; Etoposide; Fusion Proteins, bcr-abl; Humans; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Promyelocytic, Acute; Membrane Potentials; Mitochondria; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Sphingolipids; Transfection; Tumor Cells, Cultured

1998
Clinical approach to circumvention of multidrug resistance in refractory leukemic patients: association of cyclosporin A with etoposide.
    Journal of experimental & clinical cancer research : CR, 1997, Volume: 16, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blast Crisis; Child; Cyclosporine; Drug Resistance, Multiple; Etoposide; Female; Growth Inhibitors; Humans; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured

1997
Etoposide targets topoisomerase IIalpha and IIbeta in leukemic cells: isoform-specific cleavable complexes visualized and quantified in situ by a novel immunofluorescence technique.
    Molecular pharmacology, 1998, Volume: 54, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; DNA Topoisomerases, Type II; DNA-Binding Proteins; Dose-Response Relationship, Drug; Etoposide; Fluorescent Antibody Technique; Humans; In Situ Hybridization, Fluorescence; Isoenzymes; Leukemia; Tumor Cells, Cultured

1998
Case 17: Essential thrombocythaemia with inversion 3 terminating in acute leukaemia.
    Leukemia & lymphoma, 1998, Volume: 30, Issue:5-6

    Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Chromosome Inversion; Chromosomes, Human, Pair 3; Cytarabine; Etoposide; Fatal Outcome; Female; Humans; Karyotyping; Leukemia; Middle Aged; Mitoxantrone; Thrombocythemia, Essential

1998
Graft rejection and recovery of host-derived hematopoiesis after allogeneic bone marrow transplantation: relation to conditioning with high dose etoposide and total body irradiation.
    International journal of hematology, 1998, Volume: 68, Issue:1

    Topics: Acute Disease; Adult; Antineoplastic Agents, Phytogenic; Bone Marrow Transplantation; Etoposide; Graft Rejection; Hematopoiesis; Humans; Leukemia; Male; Transplantation, Homologous; Whole-Body Irradiation

1998
The relationship between modulation of MDR and glutathione in MRP-overexpressing human leukemia cells.
    Biochemical pharmacology, 1998, Apr-15, Volume: 55, Issue:8

    Topics: Antineoplastic Agents; ATP-Binding Cassette Transporters; Buthionine Sulfoximine; Cell Division; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Genes, MDR; Glutathione; Humans; Leukemia; Multidrug Resistance-Associated Proteins; Tumor Cells, Cultured

1998
Role of oxygen radicals generated by NADPH oxidase in apoptosis induced in human leukemia cells.
    The Journal of clinical investigation, 1998, Dec-01, Volume: 102, Issue:11

    Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Camptothecin; Catalase; Cell Differentiation; Cell Line; DNA Fragmentation; Enzyme Inhibitors; Etoposide; Flow Cytometry; Granulomatous Disease, Chronic; Humans; Hydrogen Peroxide; Leukemia; Membrane Glycoproteins; Monocytes; NADPH Oxidase 2; NADPH Oxidases; Neoplasm Proteins; Neutrophils; NF-kappa B; Pyrrolidines; Reactive Oxygen Species; Staurosporine; Thiocarbamates; Topoisomerase I Inhibitors; Tumor Cells, Cultured; Ultraviolet Rays

1998
Signaling defect in the activation of caspase-3 and PKCdelta in human TUR leukemia cells is associated with resistance to apoptosis.
    Experimental cell research, 1999, Mar-15, Volume: 247, Issue:2

    Topics: Apoptosis; Caspase 3; Caspases; Cytarabine; Enzyme Activation; Etoposide; Humans; Isoenzymes; Leukemia; Nucleic Acid Synthesis Inhibitors; Protein Kinase C; Protein Kinase C-delta; Signal Transduction; Tumor Cells, Cultured; U937 Cells

1999
Secondary leukemia or myelodysplastic syndrome after treatment with epipodophyllotoxins.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Agents, Phytogenic; Child; Child, Preschool; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Monitoring; Etoposide; Female; Follow-Up Studies; Humans; Infant; Leukemia; Male; Myelodysplastic Syndromes; Neoplasms, Second Primary; Risk Factors

1999
Early detection by ultrasound scan of severe post-chemotherapy gut complications in patients with acute leukemia.
    Haematologica, 1999, Volume: 84, Issue:3

    Topics: Acute Disease; Adult; Anti-Infective Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dilatation, Pathologic; Enterocolitis; Etoposide; Female; Gallbladder Diseases; Gastrointestinal Diseases; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Intubation, Gastrointestinal; Leukemia; Leukemia, Myelomonocytic, Acute; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Neutropenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome; Ultrasonography

1999
Chemotherapy and donor peripheral blood progenitor cells for acute leukemia in early relapse after allogeneic bone marrow transplantation.
    Bone marrow transplantation, 1999, Volume: 23, Issue:6

    Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Etoposide; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Mitoxantrone; Recurrence; Time Factors; Tissue Donors; Transplantation Chimera; Transplantation, Homologous

1999
Caspase-induced proteolysis of the cyclin-dependent kinase inhibitor p27Kip1 mediates its anti-apoptotic activity.
    Oncogene, 1999, Aug-26, Volume: 18, Issue:34

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Base Sequence; Calpain; Caspase 3; Caspase 6; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cysteine Proteinase Inhibitors; Etoposide; Humans; Leukemia; Leupeptins; Microtubule-Associated Proteins; Molecular Sequence Data; Mutation; Nucleic Acid Synthesis Inhibitors; Oligopeptides; Protein Serine-Threonine Kinases; Thimerosal; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

1999
Pharmacokinetics of anticancer drugs in vitro.
    Advances in experimental medicine and biology, 1999, Volume: 457

    Topics: Amino Acids; Antineoplastic Agents; Asparaginase; Cyclophosphamide; Cytarabine; Etoposide; HL-60 Cells; Humans; Leukemia; Tumor Cells, Cultured

1999
[Mechanism of occurrence of secondary tumors by antitumor drugs].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:13

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; DNA Repair; DNA Topoisomerases, Type II; DNA-Binding Proteins; Doxorubicin; Etoposide; Histone-Lysine N-Methyltransferase; Humans; Leukemia; Myeloid-Lymphoid Leukemia Protein; Neoplasms, Second Primary; Proto-Oncogenes; Topoisomerase II Inhibitors; Transcription Factors; Translocation, Genetic

1999
Treatment of normal and malignant cells with nucleoside analogues and etoposide enhances deoxycytidine kinase activity.
    European journal of cancer (Oxford, England : 1990), 1999, Volume: 35, Issue:13

    Topics: Antineoplastic Agents, Phytogenic; Child; Deoxycytidine Kinase; Enzyme Induction; Etoposide; Humans; Leukemia; Nucleosides; T-Lymphocytes

1999
Predictors of therapy-related leukemia and myelodysplasia following autologous transplantation for lymphoma: an assessment of risk factors.
    Blood, 2000, Mar-01, Volume: 95, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; California; Case-Control Studies; Cohort Studies; Combined Modality Therapy; Etoposide; Female; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Leukemia, Radiation-Induced; Lymphoma; Male; Middle Aged; Multivariate Analysis; Myelodysplastic Syndromes; Neoplasms, Second Primary; Odds Ratio; Radiotherapy; Retrospective Studies; Risk Factors; Transplantation Conditioning; Treatment Outcome; Whole-Body Irradiation

2000
Cell density-dependent VP-16 sensitivity of leukaemic cells is accompanied by the translocation of topoisomerase IIalpha from the nucleus to the cytoplasm.
    British journal of haematology, 2000, Volume: 108, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Blotting, Western; Cell Nucleus; Cytoplasm; DNA Topoisomerases, Type I; Drug Resistance, Neoplasm; Etoposide; Flow Cytometry; Humans; Leukemia; Multiple Myeloma; Phenotype; Translocation, Genetic; Tumor Cells, Cultured

2000
Serine palmitoyltransferase regulates de novo ceramide generation during etoposide-induced apoptosis.
    The Journal of biological chemistry, 2000, Mar-24, Volume: 275, Issue:12

    Topics: Acyltransferases; Antineoplastic Agents, Phytogenic; Apoptosis; Biological Transport; Caspases; Ceramides; Enzyme Activation; Etoposide; Humans; Leukemia; Microsomes; Models, Biological; Mycotoxins; Oxidoreductases; Palmitates; Poly(ADP-ribose) Polymerases; Protease Inhibitors; Serine C-Palmitoyltransferase; Sphingosine; Trypan Blue; Tumor Cells, Cultured

2000
Stochastic modeling of apoptosis tolerance distributions measured by multivariate flow analysis of human leukemia cells.
    Cytometry, 2000, Apr-01, Volume: 39, Issue:4

    Topics: Apoptosis; Etoposide; Flow Cytometry; Humans; Intracellular Membranes; Leukemia; Light; Likelihood Functions; Linear Models; Membrane Lipids; Membrane Potentials; Mitochondria; Multivariate Analysis; Phosphatidylserines; Scattering, Radiation; Sensitivity and Specificity; Stochastic Processes; Tumor Cells, Cultured

2000
Novobiocin-induced VP-16 accumulation and MRP expression in human leukemia and ovarian carcinoma cells.
    Anti-cancer drug design, 2000, Volume: 15, Issue:2

    Topics: Ascites; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Transport; Bone Marrow; Etoposide; Female; Humans; Kinetics; Leukemia; Multidrug Resistance-Associated Proteins; Novobiocin; Ovarian Neoplasms; Tumor Cells, Cultured

2000
E1A overcomes the apoptosis block in BCR-ABL+ leukemia cells and renders cells susceptible to induction of apoptosis by chemotherapeutic agents.
    Cancer research, 2000, Jul-15, Volume: 60, Issue:14

    Topics: Adenovirus E1A Proteins; Antibiotics, Antineoplastic; Apoptosis; Blotting, Western; Caspase 3; Caspases; CDC2 Protein Kinase; Cell Cycle; Cell Division; Daunorubicin; DNA Damage; Dose-Response Relationship, Drug; Etoposide; Flow Cytometry; Fusion Proteins, bcr-abl; Humans; K562 Cells; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Luciferases; Microscopy, Phase-Contrast; Nucleic Acid Synthesis Inhibitors; Peptides; Plasmids; Poly(ADP-ribose) Polymerases; Transfection; Tumor Cells, Cultured

2000
Antileukemic drugs increase death receptor 5 levels and enhance Apo-2L-induced apoptosis of human acute leukemia cells.
    Blood, 2000, Dec-01, Volume: 96, Issue:12

    Topics: Acute Disease; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Apoptotic Protease-Activating Factor 1; BH3 Interacting Domain Death Agonist Protein; Carrier Proteins; Caspase 3; Caspase 8; Caspase 9; Caspases; Cytarabine; Cytochrome c Group; Doxorubicin; Etoposide; HL-60 Cells; Humans; Jurkat Cells; Leukemia; Membrane Glycoproteins; Proteins; Proto-Oncogene Proteins c-bcl-2; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; U937 Cells; Up-Regulation

2000
Down-regulation of bcr-abl and bcl-x(L) expression in a leukemia cell line and its doxorubicin-resistant variant by topoisomerase II inhibitors.
    Biochemical pharmacology, 2000, Dec-15, Volume: 60, Issue:12

    Topics: Amsacrine; Antineoplastic Agents; Apoptosis; bcl-X Protein; Chromatography, High Pressure Liquid; Down-Regulation; Doxorubicin; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Fusion Proteins, bcr-abl; Humans; K562 Cells; Leukemia; Proto-Oncogene Proteins c-abl; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; Topoisomerase II Inhibitors; Tumor Cells, Cultured

2000
Chemotherapy and marrow transplantation for congenital leukaemia.
    Archives of disease in childhood. Fetal and neonatal edition, 2001, Volume: 84, Issue:1

    Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Etoposide; Female; Humans; Infant, Newborn; Leukemia; Methotrexate; Mitoxantrone; Prednisolone; Treatment Outcome; Vincristine

2001
Action of topoisomerase targeting drugs on non-Hodgkin's lymphoma and leukemia. Correlation of clinical and cell culture studies.
    Annals of the New York Academy of Sciences, 2000, Volume: 922

    Topics: Acute Disease; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase I as Topic; Cytarabine; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Neoplasm; Enzyme Inhibitors; Etoposide; Humans; Isoenzymes; Leukemia; Leukocytes; Lymphoma, Non-Hodgkin; Mitoxantrone; Polymerase Chain Reaction; RNA, Messenger; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Topotecan

2000
Combination chemotherapy of intermediate-dose cytarabine, idarubicin, plus etoposide and subsequent mobilized donor leukocyte infusion for relapsed acute leukemia after allogeneic bone marrow transplantation.
    Leukemia research, 2001, Volume: 25, Issue:4

    Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Disease-Free Survival; Etoposide; Female; Graft vs Host Disease; Hematopoietic Stem Cell Mobilization; Humans; Idarubicin; Leukemia; Leukocyte Transfusion; Male; Recurrence; Survival Rate; Transplantation, Homologous

2001
Respiratory chain-generated oxidative stress following treatment of leukemic blasts with DNA-damaging agents.
    Experimental cell research, 2001, Apr-01, Volume: 264, Issue:2

    Topics: Apoptosis; Ceramides; Cytarabine; Digitonin; DNA Damage; Electron Transport; Electron Transport Complex III; Etoposide; Gamma Rays; Leukemia; Mitochondria; Nucleic Acid Synthesis Inhibitors; Oxidative Stress; Permeability; Reactive Oxygen Species; Thioredoxins; Tumor Cells, Cultured

2001
Modulation of apoptosis by procaspase-2 short isoform: selective inhibition of chromatin condensation, apoptotic body formation and phosphatidylserine externalization.
    Oncogene, 2001, Jan-11, Volume: 20, Issue:2

    Topics: Amino Acid Motifs; Apoptosis; Base Sequence; Caspase 2; Caspases; Chromatin; Cysteine; DNA Fragmentation; Enzyme Inhibitors; Enzyme Precursors; Etoposide; Humans; Isoenzymes; Leukemia; Molecular Sequence Data; Mutation; Phosphatidylserines; Topoisomerase II Inhibitors; Transfection; Tumor Cells, Cultured

2001
Mitochondria-targeting drugs arsenic trioxide and lonidamine bypass the resistance of TPA-differentiated leukemic cells to apoptosis.
    Blood, 2001, Jun-15, Volume: 97, Issue:12

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Caspases; Cell Differentiation; Cell-Free System; Drug Resistance; Etoposide; Humans; Indazoles; Leukemia; Mitochondria; Oxides; Proto-Oncogene Proteins c-bcl-2; Tetradecanoylphorbol Acetate; U937 Cells

2001
Incidence of post transplant myelodysplasia/acute leukemia in non-Hodgkin's lymphoma patients compared with Hodgkin's disease patients undergoing autologous transplantation following cyclophosphamide, carmustine, and etoposide (CBV).
    Leukemia & lymphoma, 2001, Volume: 40, Issue:5-6

    Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Combined Modality Therapy; Cyclophosphamide; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Hodgkin Disease; Humans; Incidence; Leukemia; Lymphoma, Non-Hodgkin; Male; Middle Aged; Myelodysplastic Syndromes; Neoplasms, Second Primary; Transplantation, Autologous

2001
Leukemia cutis in an elderly patient treated with low dose cytosine arabinoside and etoposide.
    Leukemia & lymphoma, 2001, Volume: 40, Issue:3-4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Etoposide; Exanthema; Humans; Immunophenotyping; Leukemia; Leukemia, Myeloid, Acute; Male

2001
Quantitative determination of apoptosis on leukemia cells by infrared spectroscopy.
    Apoptosis : an international journal on programmed cell death, 2001, Volume: 6, Issue:4

    Topics: Apoptosis; Cell Count; Etoposide; Flow Cytometry; Leukemia; Spectrophotometry, Infrared; Tumor Cells, Cultured

2001
Benzene metabolites antagonize etoposide-stabilized cleavable complexes of DNA topoisomerase IIalpha.
    Blood, 2001, Aug-01, Volume: 98, Issue:3

    Topics: Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; Benzene; Carcinogens; DNA; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Antagonism; Drug Stability; Etoposide; Humans; Isoenzymes; Leukemia; Protein Binding; Topoisomerase II Inhibitors

2001
Bax translocation is crucial for the sensitivity of leukaemic cells to etoposide-induced apoptosis.
    Oncogene, 2001, Aug-09, Volume: 20, Issue:35

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptotic Protease-Activating Factor 1; bcl-2-Associated X Protein; Biological Transport; Caspases; DNA Damage; Etoposide; Humans; K562 Cells; Leukemia; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2

2001
Estimation of changes in vimentin filaments induced by etoposide and doxorubicin in human leukemia cell line K-562 by using immunofluorescence microscopy.
    Neoplasma, 2001, Volume: 48, Issue:4

    Topics: Antineoplastic Agents; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Humans; Intermediate Filaments; K562 Cells; Leukemia; Microscopy, Fluorescence; Vimentin

2001
Standard versus alternative myeloablative conditioning regimens in allogeneic hematopoietic stem cell transplantation for high-risk acute leukemia.
    Haematologica, 2002, Volume: 87, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Busulfan; Child; Child, Preschool; Cyclophosphamide; Cyclosporine; Cytarabine; Disease-Free Survival; Etoposide; Female; Graft Survival; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Immunosuppressive Agents; Infant; Leukemia; Life Tables; Male; Methylprednisolone; Middle Aged; Premedication; Retrospective Studies; Risk; Survival Analysis; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Whole-Body Irradiation

2002
Reduced DNA ligase activity in etoposide resistant human lymphatic leukaemia CEM cells.
    Biochemical pharmacology, 2002, Jan-15, Volume: 63, Issue:2

    Topics: Adenosine Monophosphate; Antineoplastic Agents, Phytogenic; Blotting, Western; DNA Ligase ATP; DNA Ligases; DNA Topoisomerases, Type II; Drug Resistance, Neoplasm; Etoposide; Humans; Leukemia; Tumor Cells, Cultured

2002
Allogeneic BMT for infantile acute leukemia: what is the optimal conditioning regimen?
    Bone marrow transplantation, 2002, Volume: 29, Issue:7

    Topics: Acute Disease; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Disease-Free Survival; Etoposide; Growth Disorders; Humans; Infant; Leukemia; Radiation Injuries; Transplantation Conditioning; Transplantation, Homologous; Treatment Failure; Whole-Body Irradiation

2002
Induction of apoptosis in human leukaemic cells by IPENSpm, a novel polyamine analogue and anti-metabolite.
    The Biochemical journal, 2002, Oct-01, Volume: 367, Issue:Pt 1

    Topics: Acetyltransferases; Antimetabolites; Apoptosis; Caspases; Dose-Response Relationship, Drug; Etoposide; HL-60 Cells; Humans; Leukemia; Nucleic Acid Synthesis Inhibitors; Polyamines; Time Factors; Tumor Cells, Cultured

2002
The therapy of acute leukemia in the adult: a progress report.
    Hamatologie und Bluttransfusion, 1976, Volume: 19

    Topics: Acute Disease; Adult; Antineoplastic Agents; Azacitidine; Blood Transfusion; Cytarabine; Daunorubicin; Dexamethasone; Etoposide; Granulocytes; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Patient Isolation; Platelet Transfusion; Pneumonia; Prednisone; Pyrimethamine; Remission, Spontaneous; Thioguanine; Vincristine; Zinostatin

1976
[Myelomonocytoid leukemia, abnormal cellular clone with a marker chromosome, evolution with a possible cure].
    Annales de medecine interne, 1978, Volume: 129, Issue:3

    Topics: Adult; Chromosomes, Human, 21-22 and Y; Clone Cells; Cytodiagnosis; Cytogenetics; Etoposide; Female; Humans; Leukemia; Leukemia, Myeloid

1978
[Successful therapy of chronic myelomonocytic leukemia with vp 16-213 (author's transl)].
    Blut, 1979, Volume: 38, Issue:5

    Topics: Age Factors; Aged; Chronic Disease; Etoposide; Granulocytes; Humans; Leukemia; Male; Monocytes; Podophyllotoxin

1979
Rapid remission induction in adult acute non-lymphoblastic leukaemia.
    European journal of cancer, 1978, Volume: 14, Issue:11

    Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Podophyllotoxin; Remission, Spontaneous; Sepsis; Time Factors

1978
The measurement of nuclear topoisomerase II inhibition in vitro: a possible tool for detecting resistance on a subcellular level in haematopoietic malignancies.
    European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies, 1992, Volume: 30, Issue:2

    Topics: Amsacrine; Antineoplastic Agents; Cell Nucleus; Drug Resistance; Etoposide; Humans; In Vitro Techniques; Leukemia; Leukemia, Promyelocytic, Acute; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1992
Potentiation by novobiocin of the cytotoxic activity of etoposide (VP-16) and teniposide (VM-26).
    International journal of cancer, 1992, Jul-09, Volume: 51, Issue:5

    Topics: Adenocarcinoma; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; DNA; DNA Topoisomerases, Type II; Drug Synergism; Etoposide; Humans; Leukemia; Lung Neoplasms; Novobiocin; RNA; Teniposide; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1992
Collection of peripheral blood stem cells mobilized by high-dose Ara-C plus VP-16 or aclarubicin followed by recombinant human granulocyte-colony stimulating factor.
    Bone marrow transplantation, 1992, Volume: 10, Issue:4

    Topics: Aclarubicin; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Cells; Blood Component Removal; Blood Transfusion, Autologous; Cytarabine; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Hematopoiesis; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Leukemia; Lymphoma; Male; Middle Aged; Recombinant Proteins

1992
Low-dose etoposide: a potential therapy for myelodysplastic syndromes.
    British journal of haematology, 1992, Volume: 82, Issue:2

    Topics: Acute Disease; Adult; Aged; Anemia, Refractory, with Excess of Blasts; Bone Marrow; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Myelodysplastic Syndromes

1992
Bone marrow purging in patients with refractory cancer.
    Progress in clinical and biological research, 1992, Volume: 377

    Topics: Adolescent; Adult; Bone Marrow Purging; Bone Marrow Transplantation; Breast Neoplasms; Child; Child, Preschool; Colony-Forming Units Assay; Etoposide; Female; Hematopoietic Stem Cells; Humans; In Vitro Techniques; Leukemia; Lymphoma; Male; Methylprednisolone; Middle Aged; Neoplasms; Transplantation, Autologous

1992
New perspectives on the toxicity of etoposide.
    Seminars in oncology, 1992, Volume: 19, Issue:6 Suppl 13

    Topics: Bone Marrow Diseases; Etoposide; Humans; Leukemia; Neoplasms, Second Primary; Podophyllotoxin

1992
Allogeneic bone marrow transplantation for hematological malignancies following etoposide, cyclophosphamide, and fractionated total body irradiation.
    American journal of hematology, 1992, Volume: 41, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Bone Marrow Transplantation; Carmustine; Combined Modality Therapy; Cyclophosphamide; Drug Therapy, Combination; Etoposide; Female; Humans; Injections, Intravenous; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Transplantation, Homologous; Whole-Body Irradiation

1992
Intracellular cytosine arabinoside accumulation and cytosine arabinoside triphosphate formation in leukemic blast cells is inhibited by etoposide and teniposide.
    Leukemia, 1992, Volume: 6, Issue:6

    Topics: Acute Disease; Adult; Aged; Amsacrine; Arabinofuranosylcytosine Triphosphate; Cytarabine; Drug Interactions; Etoposide; Humans; Leukemia; Middle Aged; Neoplastic Stem Cells; Phosphorylation; Teniposide; Tumor Cells, Cultured

1992
[Clinical application of enzyme inhibitors--hematologic malignancies].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49, Issue:9

    Topics: Cytarabine; Deoxycytidine; DNA Topoisomerases, Type I; Etoposide; Gemcitabine; Humans; Leukemia; Mercaptopurine; Methotrexate; Purines; Pyrimidines; Thioguanine; Topoisomerase I Inhibitors

1991
The effect of staurosporine on drug-induced, topoisomerase II-mediated DNA cleavage in human leukemia cells.
    Cancer chemotherapy and pharmacology, 1991, Volume: 29, Issue:1

    Topics: Alkaloids; Amsacrine; Cell Line; DNA Damage; DNA Topoisomerases, Type II; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Interactions; Etoposide; Humans; Leukemia; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured

1991
A combined approach for purging multidrug-resistant leukemic cell lines in bone marrow using a monoclonal antibody and chemotherapy.
    Blood, 1991, May-01, Volume: 77, Issue:9

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow; Bone Marrow Transplantation; Cell Separation; Chromium Radioisotopes; Complement System Proteins; Drug Resistance; Etoposide; Flow Cytometry; Hematopoietic Stem Cells; Humans; Leukemia; Membrane Glycoproteins; Tumor Cells, Cultured

1991
Ablative therapy in bone marrow transplantation.
    Bone marrow transplantation, 1991, Volume: 7 Suppl 1

    Topics: Bone Marrow Transplantation; Cyclophosphamide; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Lymphoma

1991
[Intensive carboquone and cryopreserved autologous bone marrow transplantation for relapsed malignancies].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Carbazilquinone; Cisplatin; Combined Modality Therapy; Cryopreservation; Etoposide; Female; Hodgkin Disease; Humans; Leukemia; Male; Middle Aged; Nimustine

1992
Improved results of allogeneic bone marrow transplantation for advanced hematologic malignancy using busulfan, cyclophosphamide and etoposide as cytoreductive and immunosuppressive therapy.
    Bone marrow transplantation, 1991, Volume: 8, Issue:6

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Child; Combined Modality Therapy; Cyclophosphamide; Drug Therapy, Combination; Etoposide; Graft vs Host Disease; Hepatic Veno-Occlusive Disease; Humans; Immunosuppressive Agents; Incidence; Leukemia; Middle Aged; Time Factors; Transplantation, Homologous

1991
[Subleukemic acute monophagocytic leukemia. A biological phenotype close to malignant histiocytosis].
    Sangre, 1991, Volume: 36, Issue:5

    Topics: Aged; Aged, 80 and over; Aneuploidy; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Doxorubicin; Etoposide; Female; Giant Cells; Histiocytic Sarcoma; Humans; Leukemia; Leukemia, Myeloid; Phagocytosis; Thioguanine

1991
Influence of immunosuppression on acute liver toxicity after intensified conditioning regimens for bone marrow transplantation in children.
    Blood, 1991, Apr-01, Volume: 77, Issue:7

    Topics: Bone Marrow Transplantation; Busulfan; Child; Cyclosporins; Drug Therapy, Combination; Etoposide; Graft vs Host Disease; Humans; Immunosuppression Therapy; Leukemia; Liver; Lymphoma, Non-Hodgkin; Myelodysplastic Syndromes; Transplantation, Autologous; Whole-Body Irradiation

1991
High-dose ara-C and etoposide in refractory or relapsing acute leukemia.
    Cancer chemotherapy and pharmacology, 1991, Volume: 28, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Recurrence; Time Factors

1991
Elimination of clonogenic tumor cells from bone marrow using methylprednisolone (MP) and etoposide VP16: an in vitro pharmacologic study.
    International journal of cell cloning, 1991, Volume: 9, Issue:5

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Cell Death; Cell Separation; Dose-Response Relationship, Drug; Etoposide; Hematopoietic Stem Cells; Humans; Leukemia; Lymphoma; Methylprednisolone; Tumor Cells, Cultured

1991
Differential in vitro sensitivity of human tumor and normal cells to chemotherapeutic agents and resistance modulators.
    International journal of cancer, 1991, Jun-19, Volume: 48, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Agents; Buthionine Sulfoximine; Cell Division; Cell Line; Cell Survival; Cisplatin; Cyclosporins; Doxorubicin; Drug Screening Assays, Antitumor; Etoposide; Humans; Kidney Neoplasms; Kinetics; Leukemia; Lymphocytes; Methionine Sulfoximine; Neurilemmoma; Tumor Cells, Cultured; Verapamil; Vincristine

1991
Modulation of etoposide (VP-16) cytotoxicity by verapamil or cyclosporine in multidrug-resistant human leukemic cell lines and normal bone marrow.
    Experimental hematology, 1990, Volume: 18, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cell Division; Cell Survival; Cyclosporins; Drug Resistance; Etoposide; Hematopoietic Stem Cells; Humans; Leukemia; Tumor Cells, Cultured; Verapamil

1990
Treatment of relapsed or refractory acute leukemia: comparison of two different regimens.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Acute Disease; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Combined Modality Therapy; Cytarabine; Etoposide; Humans; Leukemia; Mitoxantrone; Neoplasm Recurrence, Local

1990
High-dose etoposide and cyclophosphamide without bone marrow transplantation for resistant hematologic malignancy.
    Blood, 1990, Aug-01, Volume: 76, Issue:3

    Topics: Acute Disease; Blood Cells; Bone Marrow Transplantation; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Resistance; Drug Therapy, Combination; Etoposide; Hodgkin Disease; Humans; Leukemia; Lymphoma; Spleen

1990
In vitro cytotoxicity of VP-16-213 and nitrogen mustard: agonistic on tumor cells but not on normal human bone marrow progenitors.
    Experimental hematology, 1990, Volume: 18, Issue:9

    Topics: Bone Marrow; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Etoposide; Hematopoietic Stem Cells; Humans; Leukemia; Lymphoma; Nitrogen Mustard Compounds; Tumor Cells, Cultured

1990
Combined etoposide and 5-azacitidine in children and adolescents with refractory or relapsed acute nonlymphocytic leukemia: a Pediatric Oncology Group Study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:7

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Child; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia; Male; Remission Induction; Time Factors

1987
Effect of etoposide (VP16-213) on lipid peroxidation and antioxidant status in a high-dose radiochemotherapy regimen.
    Cancer chemotherapy and pharmacology, 1989, Volume: 25, Issue:3

    Topics: Anemia, Aplastic; Antioxidants; beta Carotene; Bone Marrow Transplantation; Carotenoids; Combined Modality Therapy; Etoposide; Humans; Leukemia; Lipid Peroxidation; Lipid Peroxides; Myelodysplastic Syndromes; Parenteral Nutrition; Radiotherapy Dosage; Time Factors; Vitamin E

1989
Long-term endocrine toxicity of myeloablative treatment followed by autologous bone marrow/blood derived stem cell transplantation in patients with malignant lymphohematopoietic disorders.
    Cancer, 1989, Aug-01, Volume: 64, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Combined Modality Therapy; Cyclophosphamide; Endocrine System Diseases; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Libido; Lymphoma; Male; Menstruation Disturbances; Middle Aged; Ovarian Diseases; Whole-Body Irradiation

1989
Multidrug resistance in cultured human leukemia and lymphoma cell lines detected by a monoclonal antibody, MRK16.
    Japanese journal of cancer research : Gann, 1989, Volume: 80, Issue:10

    Topics: Antibodies, Monoclonal; ATP Binding Cassette Transporter, Subfamily B, Member 1; Dactinomycin; Daunorubicin; Doxorubicin; Drug Resistance; Etoposide; Gene Expression; Humans; Leukemia; Lymphoma; Membrane Glycoproteins; Mitoxantrone; RNA, Messenger; Tumor Cells, Cultured; Vinblastine; Vincristine; Vindesine

1989
[Treatment of acute leukemia with "MB-triple V" therapy--a comparative study of "MB-triple V" therapy and B-triple V therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:12

    Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Etoposide; Female; Humans; Leukemia; Leukocyte Count; Male; Middle Aged; Mitoxantrone; Remission Induction; Vinblastine; Vincristine; Vindesine

1989
New conditioning regimens for high risk marrow transplants.
    Bone marrow transplantation, 1989, Volume: 4 Suppl 4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclophosphamide; Cyclosporins; Drug Evaluation; Etoposide; Graft vs Host Disease; Humans; Leukemia; Lymphoma; Middle Aged

1989
Characterization of resistance to VP-16 in human leukemic cell line.
    The Tohoku journal of experimental medicine, 1989, Volume: 159, Issue:4

    Topics: Cell Line; DNA, Neoplasm; Drug Resistance; Etoposide; Humans; Leukemia; Tumor Cells, Cultured

1989
Escalating doses of etoposide with cyclophosphamide and fractionated total body irradiation or busulfan as conditioning for bone marrow transplantation.
    Bone marrow transplantation, 1989, Volume: 4, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Child; Combined Modality Therapy; Cyclophosphamide; Etoposide; Graft vs Host Disease; Humans; Leukemia; Middle Aged; Whole-Body Irradiation

1989
Treatment strategies in relation to drug action.
    NCI monographs : a publication of the National Cancer Institute, 1987, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; DNA Topoisomerases, Type II; Etoposide; Hodgkin Disease; Humans; Leukemia; Lung Neoplasms; Lymphoma, Non-Hodgkin; Neoplasms; Podophyllotoxin; Teniposide

1987
Acute nonlymphocytic leukemia following etoposide and cisplatin combination chemotherapy for advanced non-small-cell carcinoma of the lung.
    Blood, 1987, Volume: 70, Issue:5

    Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Karyotyping; Leukemia; Lung Neoplasms; Male; Middle Aged

1987
Etoposide-induced DNA cleavage in human leukemia cells.
    Cancer chemotherapy and pharmacology, 1987, Volume: 20, Issue:2

    Topics: Cell Division; Cell Line; DNA Damage; DNA Topoisomerases, Type II; DNA, Neoplasm; Etoposide; Humans; Immunologic Techniques; Interleukin-2; Leukemia; Lymphocyte Activation; Neoplasm Proteins; Tumor Cells, Cultured

1987
Effect of 1-beta-D-arabinofuranosylcytosine (ara-C) on nuclear topoisomerase II activity and on the DNA cleavage and cytotoxicity produced by 4'-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA) and etoposide in m-AMSA-sensitive and -resistant human le
    Biochemical pharmacology, 1987, Dec-01, Volume: 36, Issue:23

    Topics: Amsacrine; Cell Division; Cell Nucleus; Cytarabine; DNA; DNA Topoisomerases, Type II; Drug Resistance; Etoposide; Humans; Leukemia; Tumor Cells, Cultured

1987
Altered catalytic activity of and DNA cleavage by DNA topoisomerase II from human leukemic cells selected for resistance to VM-26.
    Biochemistry, 1988, Nov-29, Volume: 27, Issue:24

    Topics: Cell Cycle; Cell Division; Cell Line; Cell Nucleus; DNA Topoisomerases, Type II; Drug Resistance; Etoposide; Humans; Kinetics; Leukemia; Substrate Specificity; Tumor Cells, Cultured

1988
Acute nonlymphocytic leukemia, preleukemia, and solid tumors following intensive chemotherapy of small cell carcinoma of the lung.
    Blood, 1985, Volume: 66, Issue:6

    Topics: Acute Disease; Carcinoma, Small Cell; Chromosome Aberrations; Chromosome Disorders; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Leukemia; Lomustine; Lung Neoplasms; Male; Methotrexate; Preleukemia; Risk; Vincristine

1985
Membrane ordering effects of the anticancer agent VM-26.
    Biochimica et biophysica acta, 1986, Dec-16, Volume: 863, Issue:2

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Carcinoma, Ehrlich Tumor; Cell Line; Cell Membrane; Cholesterol; Cyclic N-Oxides; Dimyristoylphosphatidylcholine; Electron Spin Resonance Spectroscopy; Etoposide; Humans; Leukemia; Lipid Bilayers; Liposomes; Male; Membrane Lipids; Mice; Podophyllotoxin; Spin Labels; Teniposide

1986
Fractionated total body irradiation and high-dose VP 16-213 followed by allogeneic bone marrow transplantation in advanced leukemias.
    Blood, 1988, Volume: 72, Issue:5

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Burkitt Lymphoma; Child; Combined Modality Therapy; Dose-Response Relationship, Drug; Etoposide; Graft vs Host Disease; Humans; Leukemia; Leukemia, Myeloid, Acute; Middle Aged; Prognosis; Whole-Body Irradiation

1988
["A-Triple-V" treatment of relapsed or refractory acute leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1988, Volume: 29, Issue:9

    Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Pilot Projects; Remission Induction; Vinblastine; Vincristine

1988
Preclinical studies of the combination of mafosfamide (Asta-Z 7654) and etoposide (VP-16-213) for purging leukemic autologous marrow.
    Experimental hematology, 1988, Volume: 16, Issue:2

    Topics: Antineoplastic Agents; Bone Marrow; Bone Marrow Transplantation; Cell Line; Cells, Cultured; Colony-Forming Units Assay; Cyclophosphamide; Etoposide; Humans; Leukemia; Lymphocyte Activation; Time Factors; Transplantation, Autologous

1988
Combined chemotherapy with m-amsacrine in high-risk patients with acute non-lymphocytic leukemia.
    Onkologie, 1987, Volume: 10, Issue:1

    Topics: Acute Disease; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Follow-Up Studies; Humans; Leukemia; Middle Aged; Thioguanine

1987
High-dose ara-C and VP-16 before conditioning for bone marrow transplantation in patients with high-risk leukemia.
    Seminars in oncology, 1987, Volume: 14, Issue:2 Suppl 1

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Cytarabine; Etoposide; Female; Humans; Leukemia; Male

1987
Sequential pilot studies of intensive postremission chemotherapy for acute nonlymphocytic leukemia.
    Annals of the New York Academy of Sciences, 1987, Volume: 511

    Topics: Acute Disease; Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Mitoxantrone; Pilot Projects; Thioguanine

1987
VP-16-based regimen in adult acute nonlymphoblastic leukemia.
    Oncology, 1988, Volume: 45, Issue:1

    Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Erythropoiesis; Etoposide; Hematopoietic Stem Cells; Humans; Leukemia; Thioguanine; Vincristine

1988
["B-triple V" therapy as a initial induction treatment of acute leukemias].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1987, Volume: 28, Issue:11

    Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Remission Induction; Vinblastine; Vincristine

1987
A phase I-II study of cytosine arabinoside, daunorubicin, and VP16-213 in adult patients with acute non-lymphocytic leukemia.
    Australian and New Zealand journal of medicine, 1986, Volume: 16, Issue:1

    Topics: Acute Disease; Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Evaluation; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Nausea; Stomatitis; Vomiting

1986
Phase I-II trial of VP-16 in the treatment of acute nonlymphocytic leukemia and blast crisis of chronic granulocytic leukemia.
    Medical and pediatric oncology, 1986, Volume: 14, Issue:6

    Topics: Adult; Aged; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Hematologic Diseases; Humans; Leukemia; Leukemia, Myeloid; Male; Middle Aged; Stomatitis

1986
[Phase II study of etoposide (VP-16) in the form of intravenous injection for malignant lymphomas and acute leukemias: Hanshin Cooperative Study Group for Hematological Disorders].
    Gan no rinsho. Japan journal of cancer clinics, 1987, Volume: 33, Issue:1

    Topics: Adult; Aged; Drug Evaluation; Etoposide; Female; Hodgkin Disease; Humans; Injections, Intravenous; Leukemia; Leukemia, Myeloid, Acute; Lymphoma; Lymphoma, Non-Hodgkin; Male; Middle Aged

1987
Idarubicin in combination with etoposide and cytarabine in adult untreated acute non lymphoblastic leukemia.
    European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:11

    Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Idarubicin; Leukemia; Male; Middle Aged

1987
Simple method for the administration of high-dose etoposide during autologous bone marrow transplantation.
    Cancer treatment reports, 1986, Volume: 70, Issue:6

    Topics: Adult; Aged; Bone Marrow Transplantation; Drug Evaluation; Etoposide; Humans; Infusions, Parenteral; Leukemia; Lung Neoplasms; Middle Aged; Podophyllotoxin

1986
Etoposide as an in vitro purging agent for the treatment of acute leukemias and lymphomas in conjunction with autologous bone marrow transplantation.
    Experimental hematology, 1986, Volume: 14, Issue:7

    Topics: Bone Marrow; Bone Marrow Transplantation; Colony-Forming Units Assay; Etoposide; Hematopoietic Stem Cells; Humans; Leukemia; Lymphoma; Microscopy, Electron; Podophyllotoxin; Transplantation, Autologous

1986
High-dose cyclophosphamide, BCNU, and etoposide followed by autologous bone marrow rescue as treatment for adult acute leukemia in relapse.
    American journal of clinical oncology, 1986, Volume: 9, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Cyclophosphamide; Etoposide; Humans; Leukemia; Middle Aged; Recurrence; Transplantation, Autologous

1986
Total body irradiation and high-dose etoposide: a new preparatory regimen for bone marrow transplantation in patients with advanced hematologic malignancies.
    Blood, 1987, Volume: 69, Issue:4

    Topics: Acute Disease; Adult; Bone Marrow Transplantation; Child; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Evaluation; Etoposide; Graft vs Host Disease; Humans; Infant; Leukemia; Metabolic Clearance Rate; Whole-Body Irradiation

1987
Evaluation of intensive postremission chemotherapy for adults with acute nonlymphocytic leukemia using high-dose cytosine arabinoside with L-asparaginase and amsacrine with etoposide.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:6

    Topics: Acute Disease; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cytarabine; Drug Evaluation; Etoposide; Humans; Leukemia; Middle Aged; Remission Induction; Statistics as Topic

1987
[Pharmacological information. 8. Therapeutic agents for hemophilia and leukemia].
    [Kango gijutsu] : [Nursing technique], 1986, Volume: 32, Issue:11

    Topics: Etoposide; Hemophilia A; Humans; Leukemia; Vindesine

1986
Phase II study of combination chemotherapy with etoposide and amsacrine in relapsed adult leukemia.
    Cancer treatment reports, 1986, Volume: 70, Issue:4

    Topics: Adult; Aged; Aminoacridines; Amsacrine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Bone Marrow; Drug Evaluation; Etoposide; Humans; Leukemia; Middle Aged

1986
[A new drug and current strategy in the treatment of acute non-lymphocytic leukemia in adults].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:5

    Topics: Acute Disease; Adult; Aminoacridines; Amsacrine; Anthraquinones; Antineoplastic Agents; Cytarabine; Drug Administration Schedule; Etoposide; Humans; Leukemia; Mitoxantrone

1986
Drug sensitivity and cross-resistance of the 4'-(9-acridinylamino)methanesulfon-m-anisidide-resistant subline of HL-60 human leukemia.
    Cancer research, 1986, Volume: 46, Issue:7

    Topics: Aminoacridines; Amsacrine; Cell Line; Cell Survival; Cytarabine; Doxorubicin; Drug Resistance; Etoposide; Humans; Leukemia

1986
Preclinical assessment of purging with VP-16-213: key role for long-term marrow cultures.
    Blood, 1987, Volume: 69, Issue:1

    Topics: Bone Marrow; Cells, Cultured; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Etoposide; Hematopoietic Stem Cells; Humans; Leukemia; Lymphoma

1987
Etoposide in combination with cytarabine, doxorubicin, and 6-thioguanine for treatment of acute nonlymphoblastic leukemia in a protocol adjusted for age.
    Cancer treatment reports, 1987, Volume: 71, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Bone Marrow; Cytarabine; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Thioguanine

1987
[A phase II trial of etoposide (VP-16) administered intravenously in the treatment of malignant lymphoma and acute leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1985, Volume: 26, Issue:11

    Topics: Acute Disease; Adolescent; Adult; Aged; Drug Evaluation; Etoposide; Female; Humans; Infusions, Parenteral; Leukemia; Lymphoma; Male; Middle Aged; Podophyllotoxin

1985
Phase I study of VP-16 (etoposide) and amsacrine (AMSA) in the treatment of refractory acute leukemia.
    Medical and pediatric oncology, 1985, Volume: 13, Issue:4

    Topics: Acute Disease; Adult; Aged; Aminoacridines; Amsacrine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Drug Evaluation; Drug Resistance; Etoposide; Female; Humans; Leukemia; Liver Function Tests; Male; Middle Aged

1985
Idarubicin alone or in combination with cytarabine and etoposide (3 + 3 + 5 protocol) in acute non-lymphoblastic leukaemia.
    Leukemia research, 1985, Volume: 9, Issue:5

    Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Idarubicin; Leukemia; Male; Middle Aged

1985
Effects of antileukemic agents on the activity of terminal deoxynucleotidyl transferase from human normal thymic and leukemic cells "in vitro".
    Leukemia research, 1985, Volume: 9, Issue:7

    Topics: Adolescent; Antineoplastic Agents; Child; DNA Nucleotidylexotransferase; DNA Nucleotidyltransferases; Doxorubicin; Etoposide; Female; Humans; In Vitro Techniques; Infant; Kinetics; Leukemia; Lymphocytes; Male; T-Lymphocytes; Vincristine

1985
[Phase II study of NK 171 (etoposide) on malignant lymphomas and acute leukemia. A cooperative study group on NK 171 in hematological malignancies].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:3 Pt 1

    Topics: Acute Disease; Adolescent; Adult; Aged; Alopecia; Anorexia; Drug Evaluation; Etoposide; Fatigue; Female; Humans; Leukemia; Lymphoma; Male; Middle Aged; Nausea; Podophyllotoxin

1986
[Etoposide (VP 16/NK 171) and cytosine arabinoside combination chemotherapy in refractory childhood leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:4 Pt 1

    Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Drug Administration Schedule; Etoposide; Female; Humans; Infant; Leukemia; Lymphoma; Male; Myeloproliferative Disorders; Podophyllotoxin

1986
Inhibition of 1-beta-D-arabinofuranosylcytosine transport and net accumulation by teniposide and etoposide in Ehrlich ascites cells and human leukemic blasts.
    Cancer research, 1985, Volume: 45, Issue:7

    Topics: Animals; Binding Sites; Biological Transport; Carcinoma, Ehrlich Tumor; Cells, Cultured; Cytarabine; Etoposide; Humans; Leukemia; Male; Mice; Mice, Inbred Strains; Podophyllotoxin; Teniposide; Thioinosine; Tritium

1985