etoposide has been researched along with Leukemia P388 in 56 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (21.43) | 18.7374 |
| 1990's | 35 (62.50) | 18.2507 |
| 2000's | 8 (14.29) | 29.6817 |
| 2010's | 1 (1.79) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chu, DT; Clement, JJ; Klein, LL; McDonald, EJ; Plattner, JJ; Yeung, CM | 1 |
| Jurd, L; Narayanan, VL; Paull, KD | 1 |
| Amarnath, V; Hall, IH; Lee, KH; Rice, GK | 1 |
| Bisagni, E; Croisy, A; Janin, YL; Riou, JF | 1 |
| Fujimoto, K; Kobunai, T; Nomura, M; Shibata, J; Sugimoto, Y; Terada, T; Wierzba, K; Yamada, Y; Yamashita, J; Yamazaki, R | 1 |
| Aldous, SC; Coughlin, SA; Dorff, PH; Gruett, MD; Lesher, GY; Rake, JB; Reuman, M; Singh, B; Wentland, MP | 1 |
| Daley, L; Demerseman, P; Etiévant, C; Guminski, Y; Hill, BT; Imbert, T; Kruczynski, A; Monneret, C | 1 |
| Bastow, KF; Cheng, HH; Cheng, YC; Cho, SJ; Guan, J; Gurwith, M; Lee, KH; Tachibana, Y; Zhu, XK | 1 |
| Chiba, K; Kashimoto, S; Sato, Y; Tomita, K; Tsuzuki, Y | 1 |
| Arimondo, PB; Bertounesque, E; Dauzonne, D; Duca, M; Guianvarc'h, D; Kraus-Berthier, L; Léonce, S; Meresse, P; Monneret, C; Pfeiffer, B; Pierré, A; Renard, P; Thirot, S | 1 |
| Fukuda, Y; Matsunaga, S; Sakai, K; Tanaka, R; Wada, SI; Yamada, T | 1 |
| Blokhina, SV; Goncharova, SA; Iakushchenko, TN; Konovalova, NP; Raevskaia, TA; Sen', VD | 1 |
| Kamata, J; Kitoh, K; Kotake, Y; Koyanagi, N; Nagasu, T; Nakamura, K; Niijima, J; Okada, T; Sugumi, H; Uenaka, T; Yamaguchi, A; Yoshimatsu, K; Yoshino, H | 1 |
| Bailly, C; Cuevas, C; Kluza, J; Lansiaux, A; Otero, G; Tardy, C; Vanhuyse, M | 1 |
| Bevilacqua, C; Boiocchi, M; Franceschin, A; Toffoli, G | 1 |
| Alberts, DS; Dorr, RT | 1 |
| Osann, K; Slater, L; Stupecky, M; Sweet, P; Wetzel, M | 1 |
| Elliott, WL; Howard, CT; Leopold, WR; Roberts, BJ | 1 |
| Cao, DC; Higashigawa, M; Ido, M; Inamochi, H; Kagawa, Y; Kakitou, H; Matsui, K; Sakurai, M; Yamada, S | 1 |
| Arakawa, H; Iguchi, T; Kurama, M; Mano, E; Nakagawa, S; Okura, A; Tanaka, N; Yoshinari, T | 1 |
| Dong, J; Johdo, O; Naito, M; Seimiya, H; Tatsuta, T; Tsuruo, T | 1 |
| Anyanwutaku, IO; Chen, HX; Cheng, YC; Guo, X; Ji, Z; Lee, KH | 1 |
| Baughman, TM; Bumol, TF; Cao, J; Dantzig, AH; Ehlhardt, WJ; Law, KL; Shepard, RL; Starling, JJ | 1 |
| Rose, WC | 1 |
| Bogush, TA; Chmutin, EF; Syrkin, AB | 1 |
| Cao, DC; Higashigawa, M; Hori, H; Inamochi, H; Kawasaki, H; M'soka, T; Nagata, T; Sakurai, M; Shimono, Y; Yan Mao, X | 1 |
| Barret, JM; Etiévant, C; Guminski, Y; Hill, BT; Kruczynski, A; Perrin, D; van Hille, B | 1 |
| Barret, JM; Etiévant, C; Hill, BT; Kruczynski, A; van Hille, B | 1 |
| Kawagishi, C; Kobayashi, Y; Kurosaka, K; Watanabe, N | 1 |
| Ekimoto, H; Kadota, S; Kikuchi, T; Kobayashi, F; Kuramochi, H; Kuramochi-Motegi, A; Takahashi, K; Takamori, Y | 1 |
| Campbell, ED; Carter, WH; Keefe, PA; Wampler, GL | 1 |
| Kamei, H; Naito, T; Nishiyama, Y; Obata, R; Ohnuma, T; Oki, T; Yamasaki, T | 1 |
| Blume, KG; Chao, NJ; Kühl, JS; Sikic, BI | 1 |
| Cho, J; Slater, LM; Wetzel, M | 1 |
| Higashigawa, M; Kuwabara, H; Ohkubo, T; Ooi, K; Sakurai, M | 1 |
| Hagiwara, A; Ito, M; Lee, M; Muranishi, S; Sakakura, C; Sasabe, T; Shoubayashi, S; Takahashi, T; Tashima, S | 1 |
| Ebisu, H; Inaba, M; Mitsuhashi, J; Shinoda, H; Tsuruo, T | 1 |
| Hagiwara, A; Ito, M; Muranishi, S; Okano, S; Sakakura, C; Sawai, K; Seiki, K; Shobayashi, S; Takahashi, T; Tomoda, H | 1 |
| Nakano, H | 1 |
| Hagiwara, A; Itoh, M; Iwamoto, A; Lee, M; Sakakura, C; Sasabe, T; Shimotuma, M; Shobayashi, S; Takahashi, T; Yoneyama, C | 1 |
| Hamazaki, M; Higashigawa, M; Ido, M; Nagao, Y; Sakurai, M; Shibata, T; Taniguchi, K | 1 |
| Akamatsu, K; Endo, K; Kaiho, S; Koizumi, K; Koizumi, M; Matsumoto, T; Mitsui, H; Morikawa, K; Tsunenari, T | 1 |
| Gilbert, KS; Griswold, DP; Harrison, SD; Laster, WR; Waud, WR | 1 |
| Kiue, A; Kohno, K; Kuwano, M; Naito, A; Okumura, M; Sano, T | 1 |
| Higashigawa, M; Hori, H; Ido, M; Kawasaki, H; Kuwabara, H; Nagao, Y; Ohkubo, T; Sakurai, M | 1 |
| Bugat, R; Canal, P; Chatelut, E; Chevreau, C; de Forni, M; Houin, G; Johnson, NP; Plusquellec, Y; Roche, H | 1 |
| Pratesi, G; Soranzo, C; Zunino, F | 1 |
| Basler, GA; Casazza, AM; Crosswell, AR; Rose, WC; Saulnier, M; Trail, PA | 1 |
| Iwabuchi, M; Takahashi, K | 1 |
| Ekimoto, H; Kusama, K; Nishikawa, K; Takahashi, K | 1 |
| Goldenberg, GJ; Seneviratne, C | 1 |
| Hamazaki, M; Higashigawa, M; Ido, M; Kamiya, H; Kawasaki, H; Ohkubo, T; Sakurai, M; Taniguchi, K | 1 |
| Arnold, W; Nowak, C; Steinhoff, G; Tanneberger, S | 1 |
| Murray, SL; Slater, LM; Stupecky, M; Sweet, P; Wetzel, MW | 1 |
| Hidaka, H; Ido, M; Inagaki, M; Saitoh, M; Sakurai, M; Sato, K; Watanabe, M | 1 |
| Jackson, DV; Long, TR; Morgan, TM; Rice, DG | 1 |
1 review(s) available for etoposide and Leukemia P388
| Article | Year |
|---|---|
[Antitumor agents targeting mammalian topoisomerases].
Topics: Amsacrine; Animals; Antibiotics, Antineoplastic; Diterpenes; DNA Topoisomerases, Type II; Doxorubicin; Etoposide; Leukemia P388; Mice | 1991 |
1 trial(s) available for etoposide and Leukemia P388
| Article | Year |
|---|---|
Teniposide and cisplatin given by intraperitoneal administration: preclinical and phase I/pharmacokinetic studies.
Topics: Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Evaluation; Drug Synergism; Etoposide; Female; Humans; Injections, Intraperitoneal; Leukemia P388; Leukopenia; Male; Mice; Middle Aged; Peritoneal Neoplasms; Podophyllotoxin; Remission Induction; Teniposide | 1991 |
54 other study(ies) available for etoposide and Leukemia P388
| Article | Year |
|---|---|
Synthesis and antitumor activity of structural analogues of the epipodophyllotoxins.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma; Chemical Phenomena; Chemistry; Colonic Neoplasms; Etoposide; Humans; Indans; Leukemia P388; Lung Neoplasms; Mice; Molecular Structure; Podophyllotoxin; Structure-Activity Relationship; Tumor Cells, Cultured | 1991 |
In vivo antitumor activity of 6-benzyl-1,3-benzodioxole derivatives against the P388, L1210, B16, and M5076 murine models.
Topics: Animals; Antineoplastic Agents; Astrocytoma; Bucladesine; Cell Differentiation; Dioxoles; DNA Topoisomerases, Type I; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Mice; Tubulin | 1987 |
Antitumor agents. 86. Synthesis and cytotoxicity of alpha-methylene-gamma-lactone-bearing purines.
Topics: Adenine; Animals; Antineoplastic Agents; Cell Survival; Guanine; Humans; Hypoxanthines; Indicators and Reagents; KB Cells; Lactones; Leukemia L1210; Leukemia P388; Mice; Structure-Activity Relationship | 1987 |
Synthesis and evaluation of new 6-amino-substituted benzo[c]phenanthridine derivatives.
Topics: Adenocarcinoma; Alkaloids; Animals; Antineoplastic Agents; Benzophenanthridines; Breast Neoplasms; Humans; Leukemia L1210; Leukemia P388; Mice; Molecular Structure; Phenanthridines; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1993 |
Antitumor agents. 3. Synthesis and biological activity of 4 beta-alkyl derivatives containing hydroxy, amino, and amido groups of 4'-O-demethyl-4-desoxypodophyllotoxin as antitumor agents.
Topics: Animals; Antineoplastic Agents; Etoposide; Humans; Leukemia L1210; Leukemia P388; Lung Neoplasms; Molecular Structure; Podophyllotoxin; Structure-Activity Relationship; Topoisomerase II Inhibitors; Tubulin Modulators; Tumor Cells, Cultured | 1993 |
Mammalian topoisomerase II inhibitory activity of 1-cyclopropyl-6,8- difluoro-1,4-dihydro-7-(2,6-dimethyl-4-pyridinyl)-4-oxo-3-quinolinecarb oxylic acid and related derivatives.
Topics: Animals; Anti-Infective Agents; Fluoroquinolones; HeLa Cells; Humans; Leukemia P388; Mice; Quinolones; Structure-Activity Relationship; Topoisomerase II Inhibitors | 1993 |
Synthesis and antitumor activity of new glycosides of epipodophyllotoxin, analogues of etoposide, and NK 611.
Topics: Animals; Antineoplastic Agents; Biopolymers; Drug Screening Assays, Antitumor; Female; Glycosides; Glycosylation; Humans; Inhibitory Concentration 50; Leukemia L1210; Leukemia P388; Mice; Mice, Inbred DBA; Podophyllotoxin; Stereoisomerism; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Transplantation, Heterologous; Tubulin; Tumor Cells, Cultured | 1998 |
Antitumor agents. 194. Synthesis and biological evaluations of 4-beta-mono-, -di-, and -trisubstituted aniline-4'-O-demethyl-podophyllotoxin and related compounds with improved pharmacological profiles.
Topics: Animals; Antineoplastic Agents; Benzimidazoles; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Etoposide; Female; Humans; Inhibitory Concentration 50; Leukemia P388; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Neoplasm Transplantation; Structure-Activity Relationship; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1999 |
Synthesis and structure-activity relationships of 3-substituted 1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridines as novel antitumor agents.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Humans; Leukemia P388; Mice; Naphthyridines; Structure-Activity Relationship | 2004 |
Synthesis and biological study of a new series of 4'-demethylepipodophyllotoxin derivatives.
Topics: Animals; Antineoplastic Agents; Carbamates; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Lactones; Leukemia P388; Mice; Podophyllotoxin; Structure-Activity Relationship; Topoisomerase II Inhibitors; Transplantation, Heterologous | 2005 |
Lupane and oleanane triterpenoids from the cones of Liquidamber styraciflua.
Topics: Animals; Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Hamamelidaceae; Humans; Leukemia P388; Mice; Molecular Structure; Oleanolic Acid; Plants, Medicinal; Triterpenes; Tumor Cells, Cultured | 2006 |
[Antileukemic activity and development of resistance to cisplatin (CPT) and platinum (IV)-nitroxyl complex VS118].
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Resistance, Neoplasm; Drug Synergism; Etoposide; Leukemia P388; Mice; Nitrogen Oxides; Organoplatinum Compounds; Platinum Compounds | 2011 |
Antitumor activity of ER-37328, a novel carbazole topoisomerase II inhibitor.
Topics: Amsacrine; Animals; Antineoplastic Agents; Carbazoles; Colonic Neoplasms; Cross-Linking Reagents; DNA, Neoplasm; Doxorubicin; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Female; Humans; In Vitro Techniques; Leukemia P388; Mice; Mice, Inbred C57BL; Pyrimidines; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 2002 |
Lamellarin D: a novel pro-apoptotic agent from marine origin insensitive to P-glycoprotein-mediated drug efflux.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Cell Cycle; Coumarins; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Fluoresceins; Heterocyclic Compounds, 4 or More Rings; Isoquinolines; Leukemia P388; Membrane Potentials; Mice; Mitochondria; Rhodamine 123; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Verapamil | 2005 |
Chemosensitivity of drug-sensitive and drug-resistant P388 leukemia cell lines after hyperthermic treatment.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cisplatin; Daunorubicin; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Hyperthermia, Induced; Leukemia P388; Mice | 1989 |
Skin ulceration potential without therapeutic anticancer activity for epipodophyllotoxin commercial diluents.
Topics: Adenocarcinoma; Animals; Cell Survival; Colonic Neoplasms; Etoposide; Humans; Leukemia P388; Leukemia, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Podophyllotoxin; Skin Ulcer; Solvents; Teniposide; Tumor Stem Cell Assay | 1983 |
Comparison of cyclosporin A, verapamil, PSC-833 and cremophor EL as enhancing agents of VP-16 in murine lymphoid leukemias.
Topics: Animals; Cell Survival; Cyclosporine; Cyclosporins; Drug Synergism; Etoposide; Glycerol; Leukemia L1210; Leukemia P388; Mice; Survival Analysis; Tumor Cells, Cultured; Verapamil | 1995 |
Chemotherapy with [SP-4-3-(R)]-[1,1-cyclobutanedicarboxylato(2-)](2- methyl-1,4-butanediamine-N,N')platinum (CI-973, NK121) in combination with standard agents against murine tumors in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Colonic Neoplasms; Cyclophosphamide; Doxorubicin; Drug Screening Assays, Antitumor; Etoposide; Ifosfamide; Leukemia P388; Mammary Neoplasms, Animal; Melanoma, Experimental; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Mitomycin; Sarcoma, Experimental; Vinblastine | 1994 |
Combined oral administration of etoposide and arabinofuranosylcytosine-5'-stearylphosphate enhances the antitumor effect against P388 ascites tumors.
Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleotides; Cytidine Monophosphate; Etoposide; Leukemia P388; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Time Factors; Treatment Outcome | 1994 |
Stereo (C7)-dependent topoisomerase II inhibition and tumor growth suppression by a new quinolone, BO-2367.
Topics: Animals; Anti-Infective Agents; Carcinoma; Colonic Neoplasms; DNA Topoisomerases, Type II; DNA, Neoplasm; DNA, Superhelical; Drug Screening Assays, Antitumor; Enzyme Induction; Etoposide; Female; Fluoroquinolones; Leukemia L1210; Leukemia P388; Mice; Mice, Inbred Strains; Quinolones; Stereoisomerism; Topoisomerase II Inhibitors | 1993 |
Difference between the resistance mechanisms of aclacinomycin- and adriamycin-resistant P388 cell lines.
Topics: Aclarubicin; Animals; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Nucleus; DNA Topoisomerases, Type II; DNA, Neoplasm; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Humans; Immunoblotting; Leukemia P388; Tumor Cells, Cultured; Verapamil; Vincristine | 1995 |
Activities of novel nonglycosidic epipodophyllotoxins in etoposide-sensitive and -resistant variants of human KB cells, P-388 cells, and in vivo multidrug-resistant murine leukemia cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; DNA Damage; Drug Resistance, Multiple; Etoposide; Female; Humans; KB Cells; Leukemia P388; Leukemia, Experimental; Mice; Podophyllotoxin; Topoisomerase II Inhibitors | 1996 |
Reversal of P-glycoprotein-mediated multidrug resistance by a potent cyclopropyldibenzosuberane modulator, LY335979.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Carcinoma, Non-Small-Cell Lung; Cell Line; Cell Membrane; Cell Survival; Dibenzocycloheptenes; Drug Resistance, Multiple; Etoposide; Humans; Kinetics; Leukemia P388; Lung Neoplasms; Mice; Mice, Nude; Paclitaxel; Protein Binding; Quinolines; Transplantation, Heterologous; Tumor Cells, Cultured; Vinblastine | 1996 |
Combination chemotherapy involving orally administered etoposide and JM-216 in murine tumor models.
Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Etoposide; Female; Leukemia P388; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms, Experimental; Organoplatinum Compounds | 1997 |
[The effect of topoisomerase II inhibitor, vepesid, on binding of doxorubicin with DNA in tumor cells sensitive to anthracycline].
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Ehrlich Tumor; DNA, Neoplasm; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Leukemia P388; Mice; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1997 |
Aclarubicin inhibits etoposide induced apoptosis through inhibition of RNA synthesis in P388 murine leukemic cells.
Topics: Aclarubicin; Animals; Antibiotics, Antineoplastic; Apoptosis; DNA Damage; DNA, Neoplasm; Drug Interactions; Etoposide; Flow Cytometry; G1 Phase; Leukemia P388; Mice; Neoplasm Proteins; Nucleic Acid Synthesis Inhibitors; RNA, Neoplasm; Tumor Cells, Cultured | 1998 |
F 11782, a dual inhibitor of topoisomerases I and II with an original mechanism of action in vitro, and markedly superior in vivo antitumour activity, relative to three other dual topoisomerase inhibitors, intoplicin, aclarubicin and TAS-103.
Topics: Aclarubicin; Aminoquinolines; Animals; Antineoplastic Agents; Cell Division; Enzyme Inhibitors; Etoposide; Humans; Indenes; Indoles; Leukemia L1210; Leukemia P388; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Naphthalenes; Pyrans; Pyridines; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Urinary Bladder Neoplasms | 2000 |
Characterization of the biological and biochemical activities of F 11782 and the bisdioxopiperazines, ICRF-187 and ICRF-193, two types of topoisomerase II catalytic inhibitors with distinctive mechanisms of action.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Diketopiperazines; DNA Damage; DNA Topoisomerases, Type II; DNA, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Etoposide; Female; Humans; Leukemia P388; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Naphthalenes; Neoplasm Transplantation; Piperazines; Pyrans; Razoxane; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 2000 |
Cytokine production by macrophages in association with phagocytosis of etoposide-treated P388 cells in vitro and in vivo.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Chemokine CXCL2; Chemokines; Coculture Techniques; Cytokines; Etoposide; Flow Cytometry; Humans; Interleukin-8; Leukemia P388; Macrophages; Male; Mice; Microscopy, Confocal; Neoplasm Transplantation; Oligopeptides; Phagocytosis; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2001 |
Woodfruticosin (woodfordin C), a new inhibitor of DNA topoisomerase II. Experimental antitumor activity.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Death; Doxorubicin; Etoposide; HeLa Cells; Humans; Hydrolyzable Tannins; Leukemia P388; Mice; Neoplasm Transplantation; Tannins; Topoisomerase II Inhibitors | 1992 |
Relationships between various uses of antineoplastic drug-interaction terms.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Synergism; Etoposide; Humans; Leukemia P388; Lung Neoplasms; Terminology as Topic; Tumor Cells, Cultured | 1992 |
Preparation and antitumor activity of 2''-O-, 3''-O- and 2'',3''-di-O-substituted derivatives of etoposide.
Topics: Animals; Antineoplastic Agents; Etoposide; Female; Leukemia P388; Mice; Mice, Inbred Strains | 1992 |
Use of etoposide in combination with cyclosporine for purging multidrug resistant leukemic cells from bone marrow in a mouse model.
Topics: Animals; Bone Marrow Purging; Bone Marrow Transplantation; Cyclosporine; Drug Evaluation, Preclinical; Drug Resistance; Etoposide; Leukemia P388; Mice; Tumor Stem Cell Assay | 1992 |
Cyclosporin A potentiation of VP-16: production of long-term survival in murine acute lymphatic leukemia.
Topics: Animals; Cyclosporine; Drug Synergism; Etoposide; Female; Leukemia L1210; Leukemia P388; Mice; Mice, Inbred Strains; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Survival Rate; Time Factors | 1992 |
[The effect of etoposide on influx and efflux of cytosine arabinoside in P388 murine leukemic cells].
Topics: Animals; Cytarabine; Depression, Chemical; Dose-Response Relationship, Drug; Etoposide; Leukemia P388; Mice; Tumor Cells, Cultured | 1992 |
Etoposide microcrystals suspended in oil: a new dosage form to peritoneal carcinomatosis in mice.
Topics: Animals; Carcinoma; Chemistry, Pharmaceutical; Etoposide; Injections, Intraperitoneal; Leukemia P388; Male; Mice; Mice, Inbred DBA; Mice, Inbred Strains; Neoplasm Transplantation; Oils; Peritoneal Neoplasms; Suspensions | 1992 |
Therapeutic efficacy of combination of antitumor agent with AHC-52 against multidrug-resistant cells in the intravenously inoculated P388 leukemia model.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Dihydropyridines; Doxorubicin; Drug Resistance; Drug Synergism; Etoposide; Female; Leukemia P388; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Pyrazoles; Vincristine | 1992 |
Enhanced therapeutic efficacy of intralymph-nodal etoposide on distal lymph node metastases using a new dosage format--activated carbon particles adsorbing etoposide.
Topics: Animals; Charcoal; Drug Administration Routes; Etoposide; Female; Leukemia P388; Lymph Nodes; Lymphatic Metastasis; Mice | 1992 |
[Toxic reduction and superior therapeutic effects on peritoneal carcinomatosis of etoposide particles suspended in oil in mice].
Topics: Animals; Body Weight; Delayed-Action Preparations; Etoposide; Infusions, Parenteral; Iodized Oil; Lethal Dose 50; Leukemia P388; Male; Mice; Mice, Inbred ICR; Peritonitis | 1991 |
Differential growth inhibition of isoquinolinesulfonamides H-8 and H-7 towards multidrug-resistant P388 murine leukaemia cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Cycle; Cell Division; Cell Membrane; Cell Survival; Cytosol; Doxorubicin; Drug Resistance; Etoposide; Isoquinolines; Leukemia P388; Membrane Glycoproteins; Mice; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Tumor Cells, Cultured; Vincristine | 1991 |
[Combination therapy of a new platinum complex, DWA2114R with various antitumor agents against mouse tumors in vivo].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Fibrosarcoma; Fluorouracil; Leukemia P388; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Ovarian Neoplasms; Sarcoma, Experimental; Vindesine | 1992 |
Antitumor drug cross-resistance in vivo in a cisplatin-resistant murine P388 leukemia.
Topics: Amsacrine; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; DNA Topoisomerases, Type II; Drug Resistance; Drug Synergism; Etoposide; Leukemia P388; Mice; Mice, Inbred Strains; Mitoxantrone | 1991 |
Enhancement of antitumour activity of etoposide by dihydropyridines on drug-sensitive and drug-resistant leukaemia in mice.
Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line; Dihydropyridines; Dioxins; Drug Resistance; Drug Synergism; Etoposide; Injections, Intraperitoneal; Injections, Intravenous; Leukemia P388; Male; Mice | 1991 |
Decreased DNA polymerase sensitivity to 1-beta-D-arabinofuranosylcytosine 5'-triphosphate in P388 murine leukemic cells resistant to vincristine.
Topics: Animals; Arabinofuranosylcytosine Triphosphate; Blotting, Western; Cytarabine; DNA-Directed DNA Polymerase; Doxorubicin; Drug Resistance; Etoposide; Intracellular Fluid; Leukemia P388; Mice; Nucleic Acid Synthesis Inhibitors; Thymine Nucleotides; Tumor Cells, Cultured; Vincristine | 1991 |
Different interaction of cisplatin and etoposide on in vivo and in vitro tumor systems.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dose-Response Relationship, Drug; Drug Interactions; Etoposide; Humans; Leukemia L1210; Leukemia P388; Mice; Mice, Inbred DBA; Mice, Nude; Neoplasm Transplantation; Tumor Cells, Cultured | 1990 |
Preclinical antitumor activity of a soluble etoposide analog, BMY-40481-30.
Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Drug Screening Assays, Antitumor; Etoposide; Humans; Leukemia L1210; Leukemia P388; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Neoplasm Transplantation; Organophosphorus Compounds; Tumor Cells, Cultured | 1990 |
[Kinetics of etoposide cytotoxicity against mouse P388 leukemia].
Topics: Animals; Bleomycin; Cell Cycle; Cell Survival; Cisplatin; Colony-Forming Units Assay; Cytarabine; Doxorubicin; Etoposide; Fluorouracil; Leukemia P388; Leukemia, Experimental; Melphalan; Mice; Peplomycin; Podophyllotoxin; Tumor Stem Cell Assay; Vinblastine | 1985 |
[Combination effects of etoposide with other antitumor drugs in vitro and in vivo].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Drug Screening Assays, Antitumor; Drug Synergism; Etoposide; Leukemia P388; Mercaptopurine; Mice; Mice, Inbred DBA; Mice, Inbred Strains; Tumor Cells, Cultured | 1989 |
Further characterization of drug-sensitivity and cross-resistance profiles of cloned cell lines of Adriamycin-sensitive and -resistant P388 leukemia.
Topics: Amsacrine; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Survival; Clone Cells; DNA Damage; Doxorubicin; Drug Resistance; Etoposide; Leukemia P388; Mice; Tumor Cells, Cultured; Vinblastine; Vincristine | 1989 |
Increased sensitivity to 1-beta-D-arabinofuranosylcytosine in P388 murine leukemic cells resistant to etoposide.
Topics: Animals; Arabinofuranosylcytosine Triphosphate; Cell Line; Cytarabine; Deoxyribonucleotides; Drug Resistance; Etoposide; Leukemia P388; Leukemia, Experimental; Mice | 1989 |
[Sequential animal experimental determination of optimal dosages for combinations of cytostatics using a reduced number of experimental animals (vepeside/ifosfamide combination)].
Topics: Animals; Animals, Laboratory; Antineoplastic Combined Chemotherapy Protocols; Etoposide; Ifosfamide; Leukemia P388; Mice; Research Design | 1988 |
Verapamil potentiation of VP-16-213 in acute lymphatic leukemia and reversal of pleiotropic drug resistance.
Topics: Animals; Antineoplastic Agents; Cell Survival; Cells, Cultured; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance; Drug Synergism; Etoposide; Humans; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Leukemia, Lymphoid; Mice; Podophyllotoxin; Verapamil; Vincristine | 1986 |
Decreased phorbol ester receptor and protein kinase C in P388 murine leukemic cells resistant to etoposide.
Topics: Animals; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Compartmentation; Cytosol; Doxorubicin; Drug Resistance; Etoposide; In Vitro Techniques; Leukemia P388; Leukemia, Experimental; Mice; Phorbol Esters; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Vincristine | 1987 |
Combination vincristine and VP-16-213: evaluation of drug sequence.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug Synergism; Etoposide; Leukemia P388; Leukemia, Experimental; Male; Mice; Mice, Inbred DBA; Vincristine | 1986 |