Page last updated: 2024-08-23

etoposide and Leukemia L 1210

etoposide has been researched along with Leukemia L 1210 in 86 studies

Research

Studies (86)

TimeframeStudies, this research(%)All Research%
pre-199046 (53.49)18.7374
1990's32 (37.21)18.2507
2000's8 (9.30)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hansch, C; Khwaja, TA; Selassie, CD1
Jurd, L; Narayanan, VL; Paull, KD1
Amarnath, V; Hall, IH; Lee, KH; Rice, GK1
Jardine, I; Kozlowski, J; Strife, RJ1
Bisagni, E; Croisy, A; Janin, YL; Riou, JF1
Fujimoto, K; Kobunai, T; Nomura, M; Shibata, J; Sugimoto, Y; Terada, T; Wierzba, K; Yamada, Y; Yamashita, J; Yamazaki, R1
Daley, L; Demerseman, P; Etiévant, C; Guminski, Y; Hill, BT; Imbert, T; Kruczynski, A; Monneret, C1
Annereau, JP; Bailly, C; Barret, JM; Brel, V; Delcros, JG; Guilbaud, N; Guminski, Y; Imbert, T; Kruczynski, A; Lansiaux, A; Vispé, S1
Ooi, K1
Monneret, C; Schmidt, F1
Arimondo, PB; Dauzonne, D; Duca, M; Léonce, S; Monneret, C; Pfeiffer, B; Pierré, A1
Glisson, B; Liu, L; Ross, W; Rowe, T; Yalowich, J1
Glisson, BS; Hande, KR; Ross, WE; Wozniak, AJ1
Glisson, BS; Ross, WE; Smallwood, SE1
Ross, WE; Yalowich, JC2
Ross, WE; Wozniak, AJ1
Hilliard, S; Karas, JG; Peck, C; Roberts, D1
Kikuchi, H; Kondo, S; Morimura, T; Oda, Y; Takeuchi, J; Yin, D1
Lowis, SP; Newell, DR; Pearson, AD1
Osann, K; Slater, L; Stupecky, M; Sweet, P; Wetzel, M1
Reynolds, JT; Slater, LM; Stupecky, M; Sweet, P1
Chen, XH; Ma, WY; Wang, TD; Wang, ZG; Yin, SF; Zhang, CN1
Chen, XH; Ma, WY; Wang, TD; Wang, ZG; Yin, SF; Zhang, CN; Zhuang, W1
Oka, H; Okada, H; Okura, A; Suda, H; Uemura, D; Yamada, A; Yoshinari, T1
Ford, J; Ganapathi, R; Grabowski, D; Kamath, N1
Tritton, TR; Vichi, PJ1
Lorico, A; Rappa, G; Sartorelli, AC1
Demant, EJ; Grue, P; Hansen, HH; Jensen, PB; Sehested, M; Sørensen, BS1
Higashigawa, M; Inagaki, S; Kagawa, Y; Kakitoh, H; Kawasaki, H; Kuwabara, H; Ohkubo, T; Ooi, K; Sakurai, M; Sumida, K1
Arakawa, H; Iguchi, T; Kurama, M; Mano, E; Nakagawa, S; Okura, A; Tanaka, N; Yoshinari, T1
Holm, B; Jensen, PB; Sehested, M1
Higashigawa, M; Kawasaki, H; Ohkubo, T; Ooi, K; Sakurai, M1
Ganapathi, R; Grabowski, D1
Osann, K; Slater, LM; Stupecky, M; Sweet, P1
Barret, JM; Etiévant, C; Guminski, Y; Hill, BT; Kruczynski, A; Perrin, D; van Hille, B1
Bowman, KJ; Calvert, AH; Curtin, NJ; Newell, DR1
Arimondo, P; Bailly, C; Boukarim, C; Dauzonne, D; Monneret, C1
Osann, KE; Slater, LM; Stupecky, M; Sweet, P1
Carter, SK; Slavik, M1
Adamson, RH; Mead, JA; Sieber, SM1
Allen, LM1
Coulter, D; Kalish, R; Valeriote, FA; Vietti, TJ1
Allen, L1
Dombernowsky, P; Nissen, NI1
Stähelin, H1
Avery, T; Rivera, G; Roberts, DW1
Kohn, KW; Orr, A; Pommier, Y; Riou, JF1
Cho, J; Slater, LM; Wetzel, M1
Araya, S; Liu, YP; Nakamura, T1
Baguley, BC; Finlay, GJ1
Feng, MR; Grossman, HB; Liebert, M; Mancini, WR; Wagner, JG; Wedemeyer, G; Williams, M1
Cho, J; Slater, LM; Sweet, P; Wetzel, M1
Drake, F; Ford, J; Ganapathi, R; Grabowski, D; Kamath, N; Kerrigan, D; Pommier, Y1
Pratesi, G; Soranzo, C; Zunino, F1
Fry, DW1
Kawasaki, H; Ohkubo, T; Ooi, K; Sakurai, M2
Basler, GA; Casazza, AM; Crosswell, AR; Rose, WC; Saulnier, M; Trail, PA1
Gorin, NC1
Gorycki, P; King, CK; Latham, MD; Macdonald, TL; Ross, WE1
Ellis, AL; Gewirtz, DA; Povirk, LF; Randolph, JK; Swerdlow, PS; Yalowich, JC; Yanovich, S1
Ford, J; Ganapathi, R; Grabowski, D; Heiss, C; Kerrigan, D; Pommier, Y1
Braun, ID; Kennedy, KA; Lazo, JS; Meandzija, B; Pham, ET; Smaldone, LF1
Higashigawa, M; Hori, H; Kagawa, Y; Kakito, E; Kamiya, H; Kawasaki, H; Ohkubo, T; Ooi, K; Sakurai, M; Sumida, K1
Chow, KC; Glisson, BS; Ross, WE; Sullivan, DM1
Bakic, M; Chan, D; Freireich, EJ; Marton, LJ; Zwelling, LA1
Beerman, TA; Sigmund, RD; Woynarowski, JM1
Kupfer, G; Ross, W; Rowe, T1
Glisson, BS; Hodges, PK; Ross, WE; Smallwood-Kentro, S; Sullivan, DM1
Dorr, RT; Gerner, EW; Liddil, JD1
Esnault, C; Kohn, KW; Le Pecq, JB; Markovits, J; Mattern, MR; Pommier, Y; Roques, BP1
Glatte, P; Osieka, R; Pannenbäcker, R; Schmidt, CG; Seeber, S; Soll, D1
Covey, JM; Kerrigan, D; Kohn, KW; Markovits, J; Pommier, Y; Tilchen, EJ1
Latham, MD; Ross, WE; Sullivan, DM1
Kerrigan, D; Kohn, KW; Pommier, Y1
Hayakawa, M; Morise, K; Oka, Y; Saito, H1
Higashigawa, M; Kagawa, Y; Kakito, E; Kamiya, H; Kawasaki, H; Ohkubo, T; Ooi, K; Sakurai, M; Sumida, K1
Ratain, MJ; Schilsky, RL; Senekjian, EK; Simon, T; Vogelzang, NJ; Wojack, BR1
Murray, SL; Slater, LM; Stupecky, M; Sweet, P; Wetzel, MW1
Aherene, GW; Henneberry, HP; Marks, V1
Bresson, ML; Cattan, A1
Kondo, S; Nishimura, Y; Saito, H; Takeuchi, T; Umezawa, H; Yoshikawa, H2
Kuramochi, H; Nagamine, S; Nishikawa, K; Okamoto, K; Takahashi, K1
Herrmann, R; Osswald, H; Youssef, M1

Reviews

3 review(s) available for etoposide and Leukemia L 1210

ArticleYear
[The mechanism of synergistic interaction between etoposide and cytarabine].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2002, Volume: 122, Issue:7

    Topics: Animals; Cell Cycle; Cytarabine; Deoxycytidine Kinase; DNA, Neoplasm; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Etoposide; Humans; Injections, Intraperitoneal; Leukemia L1210; Mice; Mice, Inbred Strains; Stimulation, Chemical; Time Factors

2002
Investigational drugs under study by the United States National Cancer Institute.
    Cancer treatment reviews, 1976, Volume: 3, Issue:1

    Topics: Acrylates; Alkylating Agents; Ancitabine; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Chemical Phenomena; Chemistry; Chromomycins; Cisplatin; DNA, Neoplasm; Drug Evaluation, Preclinical; Etoposide; Humans; Ifosfamide; Leukemia L1210; Mice; Mitosis; National Institutes of Health (U.S.); Neoplasms; Neoplasms, Experimental; Razoxane; Tegafur; Teniposide; United States

1976
Pharmacology of antitumor agents from higher plants.
    Cancer treatment reports, 1976, Volume: 60, Issue:8

    Topics: Animals; Antineoplastic Agents, Phytogenic; Aporphines; Camptothecin; Carcinoma, Squamous Cell; Chemical Phenomena; Chemistry; Etoposide; Humans; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymphoid; Maytansine; Melanoma; Naphthoquinones; Nasopharyngeal Neoplasms; Neoplasms; Neoplasms, Experimental; Phenanthrenes; Structure-Activity Relationship; Teniposide; Vinblastine; Vincristine

1976

Trials

1 trial(s) available for etoposide and Leukemia L 1210

ArticleYear
Hydroxyurea and etoposide: in vitro synergy and phase I clinical trial.
    Journal of the National Cancer Institute, 1988, Nov-02, Volume: 80, Issue:17

    Topics: Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation; Drug Synergism; Etoposide; Female; Humans; Hydroxyurea; Leukemia L1210; Male; Mice; Middle Aged; Neoplasms; Tumor Cells, Cultured

1988

Other Studies

82 other study(ies) available for etoposide and Leukemia L 1210

ArticleYear
Structure-activity relationships of antineoplastic agents in multidrug resistance.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:7

    Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured

1990
In vivo antitumor activity of 6-benzyl-1,3-benzodioxole derivatives against the P388, L1210, B16, and M5076 murine models.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:10

    Topics: Animals; Antineoplastic Agents; Astrocytoma; Bucladesine; Cell Differentiation; Dioxoles; DNA Topoisomerases, Type I; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Mice; Tubulin

1987
Antitumor agents. 86. Synthesis and cytotoxicity of alpha-methylene-gamma-lactone-bearing purines.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:3

    Topics: Adenine; Animals; Antineoplastic Agents; Cell Survival; Guanine; Humans; Hypoxanthines; Indicators and Reagents; KB Cells; Lactones; Leukemia L1210; Leukemia P388; Mice; Structure-Activity Relationship

1987
Synthesis, 470-MHz 1H NMR spectra, and activity of delactonized derivatives of the anticancer drug etoposide.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:9

    Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Etoposide; Leukemia L1210; Magnetic Resonance Spectroscopy; Mice; Podophyllotoxin

1982
Synthesis and evaluation of new 6-amino-substituted benzo[c]phenanthridine derivatives.
    Journal of medicinal chemistry, 1993, Nov-12, Volume: 36, Issue:23

    Topics: Adenocarcinoma; Alkaloids; Animals; Antineoplastic Agents; Benzophenanthridines; Breast Neoplasms; Humans; Leukemia L1210; Leukemia P388; Mice; Molecular Structure; Phenanthridines; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1993
Antitumor agents. 3. Synthesis and biological activity of 4 beta-alkyl derivatives containing hydroxy, amino, and amido groups of 4'-O-demethyl-4-desoxypodophyllotoxin as antitumor agents.
    Journal of medicinal chemistry, 1993, Jun-11, Volume: 36, Issue:12

    Topics: Animals; Antineoplastic Agents; Etoposide; Humans; Leukemia L1210; Leukemia P388; Lung Neoplasms; Molecular Structure; Podophyllotoxin; Structure-Activity Relationship; Topoisomerase II Inhibitors; Tubulin Modulators; Tumor Cells, Cultured

1993
Synthesis and antitumor activity of new glycosides of epipodophyllotoxin, analogues of etoposide, and NK 611.
    Journal of medicinal chemistry, 1998, Nov-05, Volume: 41, Issue:23

    Topics: Animals; Antineoplastic Agents; Biopolymers; Drug Screening Assays, Antitumor; Female; Glycosides; Glycosylation; Humans; Inhibitory Concentration 50; Leukemia L1210; Leukemia P388; Mice; Mice, Inbred DBA; Podophyllotoxin; Stereoisomerism; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Transplantation, Heterologous; Tubulin; Tumor Cells, Cultured

1998
F14512, a potent antitumor agent targeting topoisomerase II vectored into cancer cells via the polyamine transport system.
    Cancer research, 2008, Dec-01, Volume: 68, Issue:23

    Topics: Animals; Binding, Competitive; Biogenic Polyamines; Breast Neoplasms; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; DNA Damage; DNA Topoisomerases, Type II; DNA, Neoplasm; Drug Delivery Systems; Etoposide; Female; Humans; Leukemia L1210; Lung Neoplasms; Mice; Mice, Nude; Neoplasms; Podophyllotoxin; Topoisomerase II Inhibitors; Xenograft Model Antitumor Assays

2008
Prodrug Mono Therapy: synthesis and biological evaluation of an etoposide glucuronide-prodrug.
    Bioorganic & medicinal chemistry, 2003, May-15, Volume: 11, Issue:10

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Drug Stability; Etoposide; Glucuronidase; Leukemia L1210; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Prodrugs; Solubility

2003
Novel carbamate derivatives of 4-beta-amino-4'-O-demethyl-4-desoxypodophyllotoxin as inhibitors of topoisomerase II: synthesis and biological evaluation.
    Organic & biomolecular chemistry, 2005, Mar-21, Volume: 3, Issue:6

    Topics: Animals; Antineoplastic Agents; Carbamates; Cell Division; DNA; DNA Damage; Enzyme Inhibitors; Etoposide; G2 Phase; Leukemia L1210; Mice; Molecular Structure; Podophyllotoxin; Structure-Activity Relationship; Topoisomerase II Inhibitors

2005
Role of topoisomerase II in mediating epipodophyllotoxin-induced DNA cleavage.
    Cancer research, 1984, Volume: 44, Issue:12 Pt 1

    Topics: Animals; Cattle; Cell Nucleus; Cell Survival; DNA Topoisomerases, Type II; DNA, Neoplasm; Etoposide; Leukemia L1210; Mice; Podophyllotoxin; Structure-Activity Relationship; Teniposide; Thymus Gland

1984
Inhibition of etoposide-induced DNA damage and cytotoxicity in L1210 cells by dehydrogenase inhibitors and other agents.
    Cancer research, 1984, Volume: 44, Issue:2

    Topics: Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Animals; Benzoates; Benzoic Acid; Cell Survival; Disulfiram; Ditiocarb; DNA; Etoposide; Leukemia L1210; Mice; NADP; Podophyllotoxin; Thiocarbamates

1984
Characterization of VP-16-induced DNA damage in isolated nuclei from L1210 cells.
    Biochimica et biophysica acta, 1984, Oct-05, Volume: 783, Issue:1

    Topics: Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; DNA; Etoposide; Hydrogen-Ion Concentration; Leukemia L1210; Magnesium; Mice; Nucleotides; Podophyllotoxin; Temperature

1984
Potentiation of etoposide-induced DNA damage by calcium antagonists in L1210 cells in vitro.
    Cancer research, 1984, Volume: 44, Issue:8

    Topics: Animals; Cell Division; Cell Nucleus; Cell Survival; DNA Replication; DNA, Neoplasm; Drug Synergism; Etoposide; Gallopamil; Kinetics; Leukemia L1210; Mice; Podophyllotoxin; Verapamil

1984
DNA damage as a basis for 4'-demethylepipodophyllotoxin-9-(4,6-O-ethylidene-beta-D-glucopyranoside) (etoposide) cytotoxicity.
    Cancer research, 1983, Volume: 43, Issue:1

    Topics: Animals; Chemical Phenomena; Chemistry; Colony-Forming Units Assay; DNA; DNA, Single-Stranded; Dose-Response Relationship, Drug; Etoposide; Leukemia L1210; Mice; Podophyllotoxin

1983
Response of L1210 leukemia to treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea plus 4'-demethylepipodophyllotoxin-9-(4,6-O-2-thenylidene-beta-D-glucopyranoside).
    Cancer research, 1981, Volume: 41, Issue:10

    Topics: Animals; Carmustine; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Etoposide; Female; Leukemia L1210; Mice; Mice, Inbred Strains; Podophyllotoxin; Prognosis

1981
Transfection with a bcl-2 expression vector protects transplanted bone marrow from chemotherapy-induced myelosuppression.
    Cancer research, 1994, Jun-01, Volume: 54, Issue:11

    Topics: Animals; Antineoplastic Agents; Bone Marrow; Cell Division; Cell Survival; Doxorubicin; Drug Interactions; Etoposide; Granulocyte Colony-Stimulating Factor; Leukemia L1210; Leukocyte Count; Mice; Neutrophils; Proto-Oncogenes; Recombinant Proteins; Transfection

1994
Exposure and schedule dependency of etoposide in neuroblastoma and leukaemia cells in vitro.
    European journal of cancer (Oxford, England : 1990), 1995, Volume: 31A, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Survival; Culture Media; Dose-Response Relationship, Drug; Drug Stability; Etoposide; Humans; Leukemia L1210; Neuroblastoma; Tumor Cells, Cultured; Tumor Stem Cell Assay

1995
Comparison of cyclosporin A, verapamil, PSC-833 and cremophor EL as enhancing agents of VP-16 in murine lymphoid leukemias.
    Leukemia research, 1995, Volume: 19, Issue:8

    Topics: Animals; Cell Survival; Cyclosporine; Cyclosporins; Drug Synergism; Etoposide; Glycerol; Leukemia L1210; Leukemia P388; Mice; Survival Analysis; Tumor Cells, Cultured; Verapamil

1995
Cyclosporin A/VP-16 produced immunity to L1210 leukemia: the participation of cytotoxic CD8 T-lymphocytes.
    Clinical immunology and immunopathology, 1995, Volume: 75, Issue:3

    Topics: Animals; CD8-Positive T-Lymphocytes; Cyclosporine; Cytotoxicity, Immunologic; Etoposide; Immunity, Cellular; Immunization, Passive; Leukemia L1210; Lymphocyte Depletion; Mice; Spleen; T-Lymphocytes, Cytotoxic

1995
[Synthesis and antitumor activity of 4-O-(halogenated) acyl-4'-demethylepipodophyllotoxin analogues].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1993, Volume: 28, Issue:10

    Topics: Animals; Etoposide; Humans; KB Cells; Leukemia L1210; Mice; Podophyllotoxin; Tumor Cells, Cultured

1993
[Synthesis and antitumor activity of 4-S-(5-amido-1,3,4-thiodiazol-2-yl)4-deoxy-4'-demethylepipodophyllotoxi n analogues].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1993, Volume: 28, Issue:10

    Topics: Animals; Etoposide; Humans; KB Cells; Leukemia L1210; Podophyllotoxin; Tumor Cells, Cultured

1993
Inhibition of topoisomerase II by a novel antitumor cyclic depsipeptide, BE-22179.
    Japanese journal of cancer research : Gann, 1994, Volume: 85, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; DNA Topoisomerases, Type I; Echinomycin; Etoposide; Leukemia L1210; Nucleic Acid Conformation; Peptides; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1994
Calmodulin inhibitor trifluoperazine in combination with doxorubicin induces the selection of tumour cells with the multidrug resistant phenotype.
    British journal of cancer, 1993, Volume: 67, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calmodulin; Carrier Proteins; Cell Division; DNA Damage; DNA Topoisomerases, Type II; DNA, Neoplasm; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Etoposide; Leukemia L1210; Membrane Glycoproteins; Mice; Phenotype; Trifluoperazine; Tumor Cells, Cultured

1993
Protection from adriamycin cytotoxicity in L1210 cells by brefeldin A.
    Cancer research, 1993, Nov-01, Volume: 53, Issue:21

    Topics: Amsacrine; Animals; Biological Transport; Brefeldin A; Cell Survival; Cyclopentanes; DNA Damage; DNA Repair; Doxorubicin; Drug Synergism; Endoplasmic Reticulum; Etoposide; Golgi Apparatus; Kinetics; Leukemia L1210; Mice; Microtubules; Nocodazole; Paclitaxel; Temperature; Tumor Cells, Cultured; Tumor Stem Cell Assay

1993
Reversal of etoposide resistance in non-P-glycoprotein expressing multidrug resistant tumor cell lines by novobiocin.
    Cancer research, 1993, Nov-15, Volume: 53, Issue:22

    Topics: Adenocarcinoma; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Colonic Neoplasms; DNA Topoisomerases, Type II; DNA, Neoplasm; Drug Resistance; Etoposide; Flow Cytometry; Humans; Leukemia L1210; Lung Neoplasms; Membrane Glycoproteins; Mice; Novobiocin; Tumor Cells, Cultured

1993
Targeting the cytotoxicity of topoisomerase II-directed epipodophyllotoxins to tumor cells in acidic environments.
    Cancer research, 1994, Jun-01, Volume: 54, Issue:11

    Topics: Amsacrine; Animals; Carcinoma, Small Cell; Chloroquine; DNA Damage; DNA Topoisomerases, Type II; DNA, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Etoposide; Humans; Hydrogen-Ion Concentration; Leukemia L1210; Lung Neoplasms; Mice; Tumor Cells, Cultured

1994
Enhanced incorporation of 1-beta-D-arabinofuranosylcytosine by pretreatment with etoposide.
    Cancer investigation, 1993, Volume: 11, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Leukemia L1210; Male; Mice; Mice, Inbred Strains

1993
Stereo (C7)-dependent topoisomerase II inhibition and tumor growth suppression by a new quinolone, BO-2367.
    Japanese journal of cancer research : Gann, 1993, Volume: 84, Issue:7

    Topics: Animals; Anti-Infective Agents; Carcinoma; Colonic Neoplasms; DNA Topoisomerases, Type II; DNA, Neoplasm; DNA, Superhelical; Drug Screening Assays, Antitumor; Enzyme Induction; Etoposide; Female; Fluoroquinolones; Leukemia L1210; Leukemia P388; Mice; Mice, Inbred Strains; Quinolones; Stereoisomerism; Topoisomerase II Inhibitors

1993
ICRF-187 rescue in etoposide treatment in vivo. A model targeting high-dose topoisomerase II poisons to CNS tumors.
    Cancer chemotherapy and pharmacology, 1996, Volume: 38, Issue:3

    Topics: Amsacrine; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Blood-Brain Barrier; Brain Neoplasms; Carcinoma, Ehrlich Tumor; Central Nervous System Neoplasms; DNA Topoisomerases, Type II; Etoposide; Female; Injections, Intraperitoneal; Lethal Dose 50; Leukemia L1210; Male; Mice; Mice, Inbred DBA; Paclitaxel; Razoxane; Structure-Activity Relationship

1996
Increased deoxycytidine kinase activity by etoposide in L1210 murine leukemic cells.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:10

    Topics: Animals; Cytarabine; Deoxycytidine Kinase; Etoposide; Leukemia L1210; Methotrexate; Mice; Phosphorylation

1996
Cytotoxic efficacy with combinations of topoisomerase I and topoisomerase II inhibitors in sensitive and multidrug-resistant L1210 mouse leukemia cells.
    Annals of the New York Academy of Sciences, 1996, Dec-13, Volume: 803

    Topics: Amsacrine; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Resistance, Multiple; Drug Synergism; Enzyme Inhibitors; Etoposide; Leukemia L1210; Mice; Mitoxantrone; Topoisomerase I Inhibitors; Topotecan

1996
Superiority of cyclosporin A over PSC-833 in enhancement of VP-16 efficacy in murine tumors in vivo.
    Cancer chemotherapy and pharmacology, 1997, Volume: 39, Issue:5

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cyclosporine; Cyclosporins; Drug Synergism; Etoposide; Female; Immunosuppressive Agents; Leukemia L1210; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Survival Rate; Time Factors

1997
F 11782, a dual inhibitor of topoisomerases I and II with an original mechanism of action in vitro, and markedly superior in vivo antitumour activity, relative to three other dual topoisomerase inhibitors, intoplicin, aclarubicin and TAS-103.
    Cancer chemotherapy and pharmacology, 2000, Volume: 46, Issue:2

    Topics: Aclarubicin; Aminoquinolines; Animals; Antineoplastic Agents; Cell Division; Enzyme Inhibitors; Etoposide; Humans; Indenes; Indoles; Leukemia L1210; Leukemia P388; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Naphthalenes; Pyrans; Pyridines; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Urinary Bladder Neoplasms

2000
Differential effects of the poly (ADP-ribose) polymerase (PARP) inhibitor NU1025 on topoisomerase I and II inhibitor cytotoxicity in L1210 cells in vitro.
    British journal of cancer, 2001, Jan-05, Volume: 84, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; DNA Damage; DNA, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Inhibitors; Etoposide; Leukemia L1210; Nucleic Acid Synthesis Inhibitors; Proteins; Quinazolines; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

2001
Design of two etoposide-amsacrine conjugates: topoisomerase II and tubuline polymerization inhibition and relation to cytotoxicity.
    Anti-cancer drug design, 2000, Volume: 15, Issue:6

    Topics: Amsacrine; Animals; Base Sequence; Biopolymers; DNA Topoisomerases, Type II; DNA, Neoplasm; Etoposide; Leukemia L1210; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Topoisomerase II Inhibitors; Tubulin; Tubulin Modulators; Tumor Cells, Cultured

2000
Enhancement of leukemia rejection by mice successfully treated for L1210 leukemia due to low dose compared to high dose VP-16.
    Leukemia research, 2002, Volume: 26, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Concanavalin A; Cyclosporine; Cyclosporins; Drug Screening Assays, Antitumor; Etoposide; Graft Rejection; Immunosuppressive Agents; Leukemia L1210; Lymphocyte Activation; Mice; Mice, Inbred DBA; Neoplasm Transplantation; Phytohemagglutinins

2002
Comparison of uptake and binding of two epipodophyllotoxin glucopyranosides, 4'-demethyl epipodophyllotoxin thenylidene-beta-D-glucoside and 4'-demethyl epipodophyllotoxin ethylidene-beta-D-glucoside, in the L1210 leukemia cell.
    Cancer research, 1978, Volume: 38, Issue:8

    Topics: Animals; Binding Sites; Biological Transport; Cell Nucleus; Etoposide; Kinetics; Leukemia L1210; Mice; Mice, Inbred DBA; Podophyllotoxin; Teniposide; Thermodynamics; Vinblastine

1978
Kinetics of cytotoxicity of VM-26 and VP-16-213 on L1210 leukemia and hematopoietic stem cells.
    Cancer treatment reports, 1978, Volume: 62, Issue:9

    Topics: Animals; Cell Survival; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Etoposide; Hematopoietic Stem Cells; Leukemia L1210; Podophyllotoxin; Rats; Teniposide; Time Factors

1978
The role of drug disposition kinetics on cellular transport of the antineoplastic agent VM-26.
    Drug metabolism reviews, 1978, Volume: 8, Issue:1

    Topics: Animals; Biological Transport, Active; Chemical Phenomena; Chemistry; Diffusion; Etoposide; Kinetics; Leukemia L1210; Mice; Models, Biological; Podophyllotoxin; Protein Binding; Serum Albumin; Teniposide

1978
Combination chemotherapy with 4'Demethylepipodophyllotoxin 9-(4,6-0-ethylidene-beta-D-glucopyranoside), VP 16-213 (NSC 141540) in L1210 leukemia.
    European journal of cancer, 1976, Volume: 12, Issue:3

    Topics: Animals; Antineoplastic Agents; Carmustine; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Drug Therapy, Combination; Etoposide; Female; Fluorouracil; Leukemia L1210; Male; Mercaptopurine; Methotrexate; Mice; Mice, Inbred DBA; Podophyllotoxin; Vincristine

1976
Delayed toxicity of epipodophyllotoxin derivatives (VM 26 and VP 16-213), due to a local effect.
    European journal of cancer, 1976, Volume: 12, Issue:11

    Topics: Animals; Dose-Response Relationship, Drug; Etoposide; Female; Injections, Intraperitoneal; Injections, Intravenous; Leukemia L1210; Liver; Lung; Male; Mice; Organ Size; Podophyllotoxin; Rats; Teniposide; Time Factors

1976
Response of L1210 to combinations of cytosine arabinoside and VM-26 or VP16-213.
    European journal of cancer, 1975, Volume: 11, Issue:9

    Topics: Animals; Cytarabine; Drug Therapy, Combination; Etoposide; Female; Leukemia L1210; Leukemia, Experimental; Mice; Podophyllotoxin; Pyrans; Teniposide

1975
Differential effects of amsacrine and epipodophyllotoxins on topoisomerase II cleavage in the human c-myc protooncogene.
    Cancer research, 1992, Jun-01, Volume: 52, Issue:11

    Topics: Amsacrine; Animals; Base Sequence; Binding Sites; Carcinoma, Small Cell; Cell Line; DNA Damage; DNA Topoisomerases, Type II; DNA, Neoplasm; Etoposide; Genes, myc; Humans; Leukemia L1210; Lung Neoplasms; Mice; Molecular Sequence Data; Promoter Regions, Genetic; Restriction Mapping; Substrate Specificity; Teniposide

1992
Cyclosporin A potentiation of VP-16: production of long-term survival in murine acute lymphatic leukemia.
    Cancer chemotherapy and pharmacology, 1992, Volume: 31, Issue:1

    Topics: Animals; Cyclosporine; Drug Synergism; Etoposide; Female; Leukemia L1210; Leukemia P388; Mice; Mice, Inbred Strains; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Survival Rate; Time Factors

1992
Arrest in late G2 or prophase of cell cycle induced by 4,4-(1,2-ethanediyl) bis (1-isobutoxycarbonyloxymethyl 2, 6-piperazinedione) (MST-16) in cultured L1210 cells.
    International journal of cancer, 1992, Jul-09, Volume: 51, Issue:5

    Topics: Animals; Antineoplastic Agents; Cell Division; DNA; Drug Interactions; Etoposide; Flow Cytometry; G2 Phase; Leukemia L1210; Mice; Piperazines; Prophase; Tumor Cells, Cultured; Vincristine

1992
Potentiation by phenylbisbenzimidazoles of cytotoxicity of anticancer drugs directed against topoisomerase II.
    European journal of cancer (Oxford, England : 1990), 1990, Volume: 26, Issue:5

    Topics: Acridines; Amsacrine; Animals; Antineoplastic Agents; Benzimidazoles; Bisbenzimidazole; Colonic Neoplasms; Doxorubicin; Drug Synergism; Etoposide; Fluorescent Dyes; Leukemia L1210; Lung Neoplasms; Melanoma; Mice; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Tumor Stem Cell Assay

1990
Effect of verapamil on the uptake and efflux of etoposide (VP16) in both sensitive and resistant cancer cells.
    Selective cancer therapeutics, 1991,Summer, Volume: 7, Issue:2

    Topics: Animals; Carcinoma, Transitional Cell; Culture Media; Drug Resistance; Etoposide; Glucose; Humans; Kinetics; Leukemia L1210; Mice; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Verapamil

1991
Development of cyclosporin A mediated immunity in L1210 leukaemia.
    British journal of cancer, 1991, Volume: 64, Issue:6

    Topics: Animals; Cyclosporine; Drug Synergism; Etoposide; Immunity; Immunization, Passive; Leukemia L1210; Mice; Spleen; Survival Analysis

1991
Trifluoperazine modulation of resistance to the topoisomerase II inhibitor etoposide in doxorubicin resistant L1210 murine leukemia cells.
    Cancer communications, 1991, Volume: 3, Issue:2

    Topics: Animals; Blotting, Western; Cell Survival; DNA; DNA Damage; DNA-Binding Proteins; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Drug Synergism; Etoposide; In Vitro Techniques; Leukemia L1210; Mice; Trifluoperazine; Tumor Cells, Cultured

1991
Different interaction of cisplatin and etoposide on in vivo and in vitro tumor systems.
    Anti-cancer drugs, 1990, Volume: 1, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dose-Response Relationship, Drug; Drug Interactions; Etoposide; Humans; Leukemia L1210; Leukemia P388; Mice; Mice, Inbred DBA; Mice, Nude; Neoplasm Transplantation; Tumor Cells, Cultured

1990
Cytotoxic synergism between trimetrexate and etoposide. Evidence that trimetrexate potentiates etoposide-induced protein-associated DNA strand breaks in L1210 leukemia cells through alterations in intracellular ATP concentrations.
    Biochemical pharmacology, 1990, Nov-01, Volume: 40, Issue:9

    Topics: Adenosine Triphosphate; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; DNA Damage; DNA, Neoplasm; Etoposide; Leukemia L1210; Mice; Quinazolines; Trimetrexate; Tumor Cells, Cultured

1990
[Etoposide-induced deoxyribonucleic acid (DNA) damage and its effects on nucleotide pools in murine leukemia L1210 cells].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1990, Volume: 110, Issue:9

    Topics: Animals; DNA Damage; DNA Repair; Etoposide; Injections, Intraperitoneal; Leukemia L1210; Mice; Nucleotides

1990
Preclinical antitumor activity of a soluble etoposide analog, BMY-40481-30.
    Investigational new drugs, 1990, Volume: 8 Suppl 1

    Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Drug Screening Assays, Antitumor; Etoposide; Humans; Leukemia L1210; Leukemia P388; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Neoplasm Transplantation; Organophosphorus Compounds; Tumor Cells, Cultured

1990
Pharmacological purging of bone marrow with drugs other than cyclophosphamide derivatives.
    Revue francaise de transfusion et immuno-hematologie, 1985, Volume: 28, Issue:5

    Topics: Animals; Antineoplastic Agents; Bleomycin; Bone Marrow; Cell Line; Cell Separation; Etoposide; Hematopoietic Stem Cells; Leukemia L1210; Leukemia, Experimental; Mice; Mice, Inbred C57BL; Podophyllotoxin

1985
Inhibition of topoisomerases by fredericamycin A.
    Cancer chemotherapy and pharmacology, 1989, Volume: 24, Issue:3

    Topics: Animals; Antibiotics, Antineoplastic; DNA Damage; DNA Polymerase II; DNA, Neoplasm; Dose-Response Relationship, Drug; Etoposide; Isoquinolines; Leukemia L1210; Mice; Spiro Compounds; Time Factors; Topoisomerase I Inhibitors; Tumor Cells, Cultured

1989
Expression of protein-associated DNA damage in the alkaline elution assay in the absence of enzymatic deproteinization.
    Cancer communications, 1989, Volume: 1, Issue:3

    Topics: Animals; Cell Line; DNA Damage; DNA Replication; DNA Topoisomerases, Type II; DNA, Neoplasm; Endopeptidase K; Etoposide; Humans; Hydrogen-Ion Concentration; Leukemia L1210; Liver Neoplasms, Experimental; Mice; Mitoxantrone; Podophyllotoxin; Protein Binding; Rats; Serine Endopeptidases; Teniposide; Tumor Cells, Cultured

1989
Progressive resistance to doxorubicin in mouse leukemia L1210 cells with multidrug resistance phenotype: reductions in drug-induced topoisomerase II-mediated DNA cleavage.
    Cancer communications, 1989, Volume: 1, Issue:4

    Topics: Amsacrine; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Nucleus; Cell Survival; DNA Topoisomerases, Type II; DNA, Viral; Doxorubicin; Drug Resistance; Etoposide; Leukemia L1210; Membrane Glycoproteins; Mice; Neoplasm Proteins; Phenotype; Simian virus 40; Tumor Cells, Cultured

1989
Lidocaine potentiation of bleomycin A2 cytotoxicity and DNA strand breakage in L1210 and human A-253 cells.
    Cancer research, 1985, Volume: 45, Issue:5

    Topics: Animals; Bleomycin; Calmodulin; Carcinoma, Squamous Cell; Cell Survival; Cells, Cultured; DNA Repair; Drug Synergism; Etoposide; Head and Neck Neoplasms; Humans; Leukemia L1210; Lidocaine; Mice

1985
Synergistic interaction between etoposide and 1-beta-D-arabinofuranosylcytosine.
    Advances in experimental medicine and biology, 1989, Volume: 253B

    Topics: Animals; Cytarabine; DNA Damage; DNA, Neoplasm; Drug Administration Schedule; Drug Synergism; Etoposide; Leukemia L1210; Male; Mice; Time Factors

1989
[Studies on the relationship between therapeutic schedule and antitumor effect of etoposide and cytosine arabinoside in murine L1210 leukemia].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1989, Volume: 109, Issue:11

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Drug Synergism; Etoposide; Leukemia L1210; Mice; Mice, Inbred Strains; Remission Induction; Survival Rate

1989
Role of proliferation in determining sensitivity to topoisomerase II-active chemotherapy agents.
    NCI monographs : a publication of the National Cancer Institute, 1987, Issue:4

    Topics: Animals; Cell Cycle; Cell Division; Cell Line; Cells, Cultured; DNA Topoisomerases, Type II; DNA, Single-Stranded; Etoposide; Flow Cytometry; Humans; Kinetics; Leukemia L1210; Leukemia, Lymphoid; Mice

1987
Effect of polyamine depletion by alpha-difluoromethylornithine or (2R,5R)-6-heptyne-2,5-diamine on drug-induced topoisomerase II-mediated DNA cleavage and cytotoxicity in human and murine leukemia cells.
    Cancer research, 1987, Dec-15, Volume: 47, Issue:24 Pt 1

    Topics: Alkynes; Amsacrine; Animals; Antineoplastic Agents; Cell Line; Cell Survival; Diamines; DNA; DNA Damage; DNA Topoisomerases, Type II; Eflornithine; Etoposide; Humans; Leukemia L1210; Leukemia, Myeloid, Acute; Mice; Ornithine Decarboxylase Inhibitors; Polyamines; Tumor Cells, Cultured

1987
Topoisomerase-II-mediated lesions in nascent DNA: comparison of the effects of epipodophyllotoxin derivatives, VM-26 and VP-16, and 9-anilinoacridine derivatives, m-AMSA and o-AMSA.
    Biochimica et biophysica acta, 1988, May-06, Volume: 950, Issue:1

    Topics: Adenosine Triphosphate; Amsacrine; Animals; Cross-Linking Reagents; DNA; DNA Damage; DNA Replication; DNA Topoisomerases, Type II; DNA, Neoplasm; Etoposide; Leukemia L1210; Mice; Novobiocin; Podophyllotoxin; Teniposide; Topoisomerase II Inhibitors

1988
Inhibition of epipodophyllotoxin cytotoxicity by interference with topoisomerase-mediated DNA cleavage.
    Biochemical pharmacology, 1985, Jul-15, Volume: 34, Issue:14

    Topics: Animals; Cell Survival; DNA; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Ethidium; Etoposide; Leukemia L1210; Mice; Podophyllotoxin

1985
Proliferation dependence of topoisomerase II mediated drug action.
    Biochemistry, 1986, Apr-22, Volume: 25, Issue:8

    Topics: Aminoacridines; Amsacrine; Animals; Cell Line; Cricetinae; Cricetulus; DNA Replication; DNA Topoisomerases, Type II; Etoposide; Female; HeLa Cells; Humans; Intercalating Agents; Kinetics; Leukemia L1210; Mice; Ovary; Plasmids; Podophyllotoxin

1986
Modulation of etoposide cytotoxicity and DNA strand scission in L1210 and 8226 cells by polyamines.
    Cancer research, 1986, Volume: 46, Issue:8

    Topics: Animals; Cell Survival; DNA Topoisomerases, Type II; DNA, Neoplasm; DNA, Single-Stranded; Eflornithine; Etoposide; Humans; Leukemia L1210; Mice; Multiple Myeloma; Nucleic Acid Conformation; Ornithine; Podophyllotoxin; Polyamines; Putrescine

1986
Effects of the bifunctional antitumor intercalator ditercalinium on DNA in mouse leukemia L1210 cells and DNA topoisomerase II.
    Cancer research, 1986, Volume: 46, Issue:11

    Topics: Amsacrine; Animals; Carbazoles; Cross-Linking Reagents; DNA Damage; DNA, Neoplasm; Etoposide; Intercalating Agents; Leukemia L1210; Mice; Nucleic Acid Conformation; Structure-Activity Relationship; Topoisomerase II Inhibitors

1986
Enhancement of etoposide-induced cytotoxicity by cyclosporin A.
    Cancer chemotherapy and pharmacology, 1986, Volume: 18, Issue:3

    Topics: Animals; Cells, Cultured; Cisplatin; Cyclosporins; Doxorubicin; Drug Interactions; Etoposide; Humans; Lethal Dose 50; Leukemia L1210; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Mice; Neoplasm Transplantation; Neoplasms, Germ Cell and Embryonal; Radiation, Ionizing

1986
Topoisomerase II-mediated DNA breaks and cytotoxicity in relation to cell proliferation and the cell cycle in NIH 3T3 fibroblasts and L1210 leukemia cells.
    Cancer research, 1987, Apr-15, Volume: 47, Issue:8

    Topics: Amsacrine; Animals; Cell Cycle; Cell Division; Cell Line; Cell Survival; DNA Damage; DNA Topoisomerases, Type I; Etoposide; Fibroblasts; Leukemia L1210; Mice; Proteins

1987
Proliferation-dependent topoisomerase II content as a determinant of antineoplastic drug action in human, mouse, and Chinese hamster ovary cells.
    Cancer research, 1987, Aug-01, Volume: 47, Issue:15

    Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Division; Cell Line; Cricetinae; Cricetulus; DNA Damage; DNA Topoisomerases, Type II; DNA, Neoplasm; Drug Resistance; Enzyme Induction; Etoposide; Female; Fibroblasts; Hematopoietic Stem Cells; Humans; Leukemia L1210; Mice; Neoplasm Proteins; Ovary

1987
Protein-linked DNA strand breaks produced by etoposide and teniposide in mouse L1210 and human VA-13 and HT-29 cell lines: relationship to cytotoxicity.
    NCI monographs : a publication of the National Cancer Institute, 1987, Issue:4

    Topics: Animals; Cell Line; Cell Survival; DNA Topoisomerases, Type II; DNA, Neoplasm; Etoposide; Humans; Kinetics; Leukemia L1210; Podophyllotoxin; Teniposide

1987
[Combination chemotherapy of UFT, etoposide and CDDP in advanced gastric cancer].
    Gan no rinsho. Japan journal of cancer clinics, 1987, Volume: 33, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia L1210; Male; Mice; Middle Aged; Radiography; Stomach Neoplasms; Tegafur; Uracil

1987
Sequence-dependent antitumor effect of VP-16 and 1-beta-D-arabinofuranosylcytosine in L1210 ascites tumor.
    European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:12

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Etoposide; Leukemia L1210; Male; Mice; Mice, Inbred Strains

1988
Verapamil potentiation of VP-16-213 in acute lymphatic leukemia and reversal of pleiotropic drug resistance.
    Cancer chemotherapy and pharmacology, 1986, Volume: 16, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Survival; Cells, Cultured; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance; Drug Synergism; Etoposide; Humans; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Leukemia, Lymphoid; Mice; Podophyllotoxin; Verapamil; Vincristine

1986
Immunocytochemical localisation of VP16-213 in normal and malignant tissues.
    Cancer letters, 1987, Oct-30, Volume: 37, Issue:2

    Topics: Animals; Etoposide; Histocytochemistry; Leukemia L1210; Mice; Neoplasms, Experimental; Tissue Distribution

1987
Vitamin A: failure to demonstrate in mice an anti-tumour effect, whether combined with cytotoxic drugs or not.
    Bulletin du cancer, 1986, Volume: 73, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cisplatin; Cyclophosphamide; Etoposide; Female; Leukemia L1210; Leukemia, Experimental; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Neoplasms, Experimental; Teniposide; Vitamin A

1986
Studies on lignan lactone antitumor agents. I. Synthesis of aminoglycosidic lignan variants related to podophyllotoxin.
    Chemical & pharmaceutical bulletin, 1986, Volume: 34, Issue:9

    Topics: Animals; Antineoplastic Agents, Phytogenic; Etoposide; Leukemia L1210; Mice; Podophyllotoxin

1986
Studies on lignan lactone antitumor agents. II. Synthesis of N-alkylamino- and 2,6-dideoxy-2-aminoglycoside lignan variants related to podophyllotoxin.
    Chemical & pharmaceutical bulletin, 1986, Volume: 34, Issue:9

    Topics: Aminoglycosides; Animals; Antineoplastic Agents, Phytogenic; Etoposide; Leukemia L1210; Mice; Podophyllotoxin

1986
Verapamil-induced augmentation of etoposide accumulation in L1210 cells in vitro.
    Cancer research, 1985, Volume: 45, Issue:4

    Topics: Animals; Cells, Cultured; DNA Repair; Drug Synergism; Etoposide; Leukemia L1210; Mice; Podophyllotoxin; Tritium; Verapamil

1985
[Antitumor effect of etoposide and its analogs].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:11

    Topics: Animals; Cell Division; Dogs; Etoposide; HeLa Cells; Humans; Leukemia L1210; Male; Mice; Podophyllotoxin; Structure-Activity Relationship

1985
Timing- and sequence-dependent synergism between etoposide and methotrexate or etoposide, methotrexate and 5-fluorouracil in advanced leukemia L1210.
    Cancer letters, 1985, Volume: 29, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Synergism; Etoposide; Female; Fluorouracil; Leukemia L1210; Methotrexate; Mice; Mice, Inbred Strains; Podophyllotoxin; Time Factors

1985