Page last updated: 2024-08-23

etoposide and Genome Instability

etoposide has been researched along with Genome Instability in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (28.00)29.6817
2010's14 (56.00)24.3611
2020's4 (16.00)2.80

Authors

AuthorsStudies
Bai, H; Dong, Y; Li, N; Liu, C; Liu, H; Xia, S; Xiao, J; Zhu, L1
Amar, L; Gantchev, J; Gill, RPK; Guerra Ordaz, DJ; Lambert, M; Lefrançois, P; Litvinov, IV; Martínez Villarreal, A; Messina-Pacheco, J; Ramchatesingh, B; Raveendra, K; Sikorski, D; Xie, P; Xu, HH1
Hashemi, F; Khadivi, F; Razavi, S1
Guo, W; Lobachev, KS; Manukyan, A; Raimer, HM; Salamon, A; Singh, S; Szlachta, K; Wang, YH1
Diao, LX; Dong, MQ; Du, LL; Lu, S; Suo, F; Wang, HT; Wei, Y1
Apel-Sarid, L; Ayyathan, DM; Blank, M; Borroni, AP; Emanuelli, A; Koganti, P; Levy-Cohen, G; Shah, PA1
Baker, K; Blackhall, F; Dive, C; Forster, M; Foy, V; Frese, KK; Gomes, F; Lallo, A; Schenk, MW1
Annala, M; Beltran, H; Chedgy, EC; Chi, KN; Donoghue, AJ; Fazli, L; Herberts, C; Hurtado-Coll, A; Konomura, S; Liew, J; Parimi, S; Ritch, E; Sboner, A; Sigouros, M; Struss, W; Vandekerkhove, G; Vergidis, J; Wyatt, AW1
Ahanonu, B; Chen, Y; Dobbin, MM; Gao, J; Kim, D; Madabhushi, R; Pan, L; Pao, PC; Qiu, Y; Tsai, LH; Zhao, Y1
Ba, X; Boldogh, I; Chen, H; Han, L; Qi, W; Wang, R; Wang, X; Xiao, T; Zeng, X1
Angeloni, C; Bocchini, M; Croco, E; Hrelia, S; Lorenzini, A; Marchionni, S; Sell, C; Stamato, T; Stefanelli, C1
Akter, S; Deshpande, RA; Furuta, R; Hoa, NN; Paull, TT; Sasanuma, H; Shimizu, T; Takeda, S; Tsuda, M; Tsutsui, K; Wang, ZQ; Zhou, ZW1
Aitkenhead, H; Amor, DJ; Drobnitzky, N; Fielden, J; Fischer, R; Freire, R; Gileadi, O; Halder, S; Kessler, BM; Lockhart, PJ; McKenna, GW; Newman, JA; Popovic, M; Ramadan, K; Singh, AN; Torrecilla, I; Vaz, B; Vendrell, I1
Aressy, B; Biard, D; Bugler, B; Ducommun, B; Valette, A1
Fattah, KR; Hendrickson, EA; Ruis, BL1
Biegel, JA; Cho, YJ; Evans, JA; Greulich, H; McKenna, ES; Moreau, LA; Pomeroy, SL; Roberts, CW; Sansam, CG; Thom, CS1
Chen, T; Hébert, J; Li, E; Richard, S; Yu, Z1
Donaldson, MM; Dornan, ES; Fisk, JC; King, LE; Melendy, T; Morgan, IM1
Bellot, GL; Koh, D; Tan, WH; Tay, LL; Wang, X1
Jiang, L; Lin, X; Liu, B; Osabe, K; Ou, X; Yang, X; Yu, Y; Zhang, C1
Karmakar, P; Mukherjee, A1
Folmes, CD; Hartjes, KA; Nelson, NG; Nelson, TJ; Oommen, S; Smith, AJ; Terzic, A1
Douglas, GR; Healy, C; Parfett, C; Polyzos, A; Yauk, CL1
Kaufmann, WK1
Hagan, CR; Rudin, CM1

Reviews

1 review(s) available for etoposide and Genome Instability

ArticleYear
Targeting DNA damage in SCLC.
    Lung cancer (Amsterdam, Netherlands), 2017, Volume: 114

    Topics: Aurora Kinases; Azepines; Benzimidazoles; Carbolines; Cell Cycle Checkpoints; Cell Proliferation; Cytotoxins; DNA Damage; DNA Repair; Etoposide; Genomic Instability; Heterocyclic Compounds, 4 or More Rings; Humans; Lung Neoplasms; Molecular Targeted Therapy; Phthalazines; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Protein Kinase Inhibitors; Pyrimidines; Rad51 Recombinase; Small Cell Lung Carcinoma

2017

Other Studies

24 other study(ies) available for etoposide and Genome Instability

ArticleYear
Altered polymerase theta expression promotes chromosomal instability in salivary adenoid cystic carcinoma.
    Journal of cellular and molecular medicine, 2022, Volume: 26, Issue:14

    Topics: Animals; Carcinoma, Adenoid Cystic; Cell Line, Tumor; Chromosomal Instability; Etoposide; Genomic Instability; Humans; Mice; Salivary Gland Neoplasms

2022
Ectopically Expressed Meiosis-Specific Cancer Testis Antigen HORMAD1 Promotes Genomic Instability in Squamous Cell Carcinomas.
    Cells, 2023, 06-14, Volume: 12, Issue:12

    Topics: Carcinoma, Squamous Cell; Cell Cycle Proteins; Cell Line, Tumor; DNA Damage; DNA Repair; Etoposide; Genomic Instability; Humans; Meiosis; Mitosis

2023
Protective effects of zinc on rat sperm chromatin integrity involvement: DNA methylation, DNA fragmentation, ubiquitination and protamination after bleomycin etoposide and cis-platin treatment.
    Theriogenology, 2020, Jan-15, Volume: 142

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chromatin; Cisplatin; Cytoprotection; DNA Fragmentation; Etoposide; Fertility Preservation; Genomic Instability; Infertility, Male; Male; Neoplasms, Germ Cell and Embryonal; Protamines; Protein Processing, Post-Translational; Rats; Rats, Wistar; Spermatozoa; Testicular Neoplasms; Ubiquitination; Zinc

2020
Topoisomerase II contributes to DNA secondary structure-mediated double-stranded breaks.
    Nucleic acids research, 2020, 07-09, Volume: 48, Issue:12

    Topics: Binding Sites; CCCTC-Binding Factor; DNA; DNA Breaks, Double-Stranded; DNA Repair; DNA Topoisomerases, Type II; Etoposide; Genome, Human; Genomic Instability; Humans; Nucleic Acid Conformation; Transcription Initiation Site

2020
SUMO-Targeted DNA Translocase Rrp2 Protects the Genome from Top2-Induced DNA Damage.
    Molecular cell, 2017, Jun-01, Volume: 66, Issue:5

    Topics: DNA Damage; DNA Helicases; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Fungal; Drug Resistance; Etoposide; Genome, Fungal; Genomic Instability; Mutation; Protein Binding; Protein Interaction Domains and Motifs; Proteolysis; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Sumoylation; Topoisomerase II Inhibitors; Ubiquitin-Protein Ligases; Ubiquitination

2017
Smurf2-Mediated Stabilization of DNA Topoisomerase IIα Controls Genomic Integrity.
    Cancer research, 2017, 08-15, Volume: 77, Issue:16

    Topics: Animals; Antigens, Neoplasm; Cell Line, Tumor; DNA Topoisomerases, Type II; DNA-Binding Proteins; Etoposide; Genomic Instability; Humans; Interphase; Mice; Mice, Knockout; Neoplasms; Ubiquitin-Protein Ligases

2017
Biallelic tumour suppressor loss and DNA repair defects in de novo small-cell prostate carcinoma.
    The Journal of pathology, 2018, Volume: 246, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carboplatin; Carcinoma, Small Cell; Cisplatin; Databases, Factual; DNA Repair; Etoposide; Gene Expression Profiling; Genes, Tumor Suppressor; Genetic Predisposition to Disease; Genomic Instability; Humans; Male; Middle Aged; Neoplasms, Complex and Mixed; Phenotype; Prostatic Neoplasms; Retrospective Studies; Time Factors; Treatment Outcome

2018
SIRT1 collaborates with ATM and HDAC1 to maintain genomic stability in neurons.
    Nature neuroscience, 2013, Volume: 16, Issue:8

    Topics: Acetylation; Amino Acid Sequence; Animals; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line; Cerebral Cortex; Comet Assay; DNA Breaks, Double-Stranded; DNA End-Joining Repair; DNA-Binding Proteins; Enzyme Activation; Etoposide; Genetic Vectors; Genomic Instability; HEK293 Cells; Hippocampus; Histone Deacetylase 1; Humans; Mice; Mice, Transgenic; Molecular Sequence Data; Neurons; Phosphorylation; Protein Interaction Mapping; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; RNA Interference; RNA, Small Interfering; Sirtuin 1; Tumor Suppressor Proteins

2013
BRG1 promotes the repair of DNA double-strand breaks by facilitating the replacement of RPA with RAD51.
    Journal of cell science, 2015, Jan-15, Volume: 128, Issue:2

    Topics: Cell Line; Chromatin Assembly and Disassembly; DNA Breaks, Double-Stranded; DNA Damage; DNA End-Joining Repair; DNA Helicases; DNA, Single-Stranded; Etoposide; Genomic Instability; Homologous Recombination; Humans; Nuclear Proteins; Rad51 Recombinase; Rad52 DNA Repair and Recombination Protein; Replication Protein A; Transcription Factors

2015
DNA Damage Detection by 53BP1: Relationship to Species Longevity.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2017, Jun-01, Volume: 72, Issue:6

    Topics: Animals; Cattle; Cell Cycle Checkpoints; Cell Line; Chiroptera; Cyclin A; Cytotoxins; DNA Damage; DNA Fragmentation; Dogs; Etoposide; Fibroblasts; Genomic Instability; Histones; Humans; Life Expectancy; Longevity; Mice; Micronuclei, Chromosome-Defective; Micronucleus Tests; NIMA-Related Kinases; Topoisomerase II Inhibitors; Tumor Suppressor p53-Binding Protein 1; Zinostatin

2017
Mre11 Is Essential for the Removal of Lethal Topoisomerase 2 Covalent Cleavage Complexes.
    Molecular cell, 2016, 11-03, Volume: 64, Issue:3

    Topics: Acid Anhydride Hydrolases; Animals; Antigens, Neoplasm; Cell Cycle Proteins; Cell Death; Cell Line, Tumor; Chickens; DNA; DNA Breaks, Double-Stranded; DNA Repair Enzymes; DNA Topoisomerases, Type II; DNA-Binding Proteins; Etoposide; Gene Expression Regulation; Genomic Instability; Humans; Lymphocytes; MRE11 Homologue Protein; Mutation; Nuclear Proteins; Phosphoric Diester Hydrolases; Poly-ADP-Ribose Binding Proteins; Recombinational DNA Repair; Signal Transduction; Topoisomerase II Inhibitors; Transcription Factors

2016
Metalloprotease SPRTN/DVC1 Orchestrates Replication-Coupled DNA-Protein Crosslink Repair.
    Molecular cell, 2016, 11-17, Volume: 64, Issue:4

    Topics: Amino Acid Sequence; Binding Sites; Cross-Linking Reagents; DNA; DNA Damage; DNA Repair; DNA Replication; DNA-Binding Proteins; Etoposide; Formaldehyde; Gene Expression; Genomic Instability; Humans; Kinetics; Mutation; Protein Binding; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Syndrome; Ultraviolet Rays

2016
Moderate variations in CDC25B protein levels modulate the response to DNA damaging agents.
    Cell cycle (Georgetown, Tex.), 2008, Jul-15, Volume: 7, Issue:14

    Topics: cdc25 Phosphatases; Cell Death; Cell Line, Tumor; DNA Damage; Doxorubicin; Etoposide; Gamma Rays; Genomic Instability; Humans; Mutagens; Spheroids, Cellular

2008
The catalytic subunit of DNA-dependent protein kinase regulates proliferation, telomere length, and genomic stability in human somatic cells.
    Molecular and cellular biology, 2008, Volume: 28, Issue:20

    Topics: Biomarkers; Catalytic Domain; Cell Cycle; Cell Proliferation; DNA Damage; DNA-Activated Protein Kinase; Etoposide; Gene Targeting; Genomic Instability; HCT116 Cells; Heterozygote; Homozygote; Humans; Telomere

2008
Loss of the epigenetic tumor suppressor SNF5 leads to cancer without genomic instability.
    Molecular and cellular biology, 2008, Volume: 28, Issue:20

    Topics: Animals; Cell Line, Tumor; Chromosomal Proteins, Non-Histone; Cisplatin; Cyclin D1; Diploidy; DNA Damage; DNA Repair; DNA-Binding Proteins; Epigenesis, Genetic; Etoposide; G2 Phase; Genomic Instability; Histones; Humans; Mice; Neoplasms; Phenotype; Polymorphism, Single Nucleotide; Protein Transport; Rhabdoid Tumor; SMARCB1 Protein; Transcription Factors

2008
A mouse PRMT1 null allele defines an essential role for arginine methylation in genome maintenance and cell proliferation.
    Molecular and cellular biology, 2009, Volume: 29, Issue:11

    Topics: Adaptor Proteins, Signal Transducing; Alleles; Animals; Arginine; Cell Proliferation; DNA; DNA Damage; DNA Repair Enzymes; DNA-Binding Proteins; Down-Regulation; Embryo, Mammalian; Etoposide; Female; Fibroblasts; Genome; Genomic Instability; Interphase; Methylation; Mice; Mice, Inbred C57BL; Mitosis; MRE11 Homologue Protein; Protein-Arginine N-Methyltransferases; Rad51 Recombinase; Radiation, Ionizing; RNA-Binding Proteins

2009
Human papillomavirus E1 and E2 mediated DNA replication is not arrested by DNA damage signalling.
    Virology, 2010, Oct-10, Volume: 406, Issue:1

    Topics: Antigens, Viral, Tumor; Cell Line; DNA Breaks, Double-Stranded; DNA Damage; DNA Replication; DNA-Binding Proteins; DNA, Viral; Etoposide; Female; Genomic Instability; Human papillomavirus 11; Humans; Papillomaviridae; Papillomavirus Infections; Signal Transduction; Uterine Cervical Neoplasms; Viral Proteins; Virus Integration; Virus Replication

2010
Reliability of tumor primary cultures as a model for drug response prediction: expression profiles comparison of tissues versus primary cultures from colorectal cancer patients.
    Journal of cancer research and clinical oncology, 2012, Volume: 138, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Cisplatin; Colorectal Neoplasms; Deoxycytidine; Down-Regulation; Doxorubicin; Etoposide; Floxuridine; Fluorescent Antibody Technique; Fluorouracil; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genomic Instability; Humans; Irinotecan; Metaphase; Paclitaxel; Polymerase Chain Reaction; Predictive Value of Tests; Protein Array Analysis; Reproducibility of Results; Tegafur; Tissue Array Analysis; Tumor Cells, Cultured; Up-Regulation; Uracil

2012
Changes in DNA methylation and transgenerational mobilization of a transposable element (mPing) by the topoisomerase II inhibitor, etoposide, in rice.
    BMC plant biology, 2012, Apr-09, Volume: 12

    Topics: Base Sequence; Cytosine; DNA Methylation; DNA Transposable Elements; Epigenesis, Genetic; Etoposide; Genes, Plant; Genetic Loci; Genomic Instability; Genotype; Inheritance Patterns; Oryza; Penetrance; Plant Cells; Seeds; Self-Fertilization; Topoisomerase II Inhibitors; Transcriptional Activation

2012
Attenuation of PTEN perturbs genomic stability via activation of Akt and down-regulation of Rad51 in human embryonic kidney cells.
    Molecular carcinogenesis, 2013, Volume: 52, Issue:8

    Topics: Antineoplastic Agents, Phytogenic; Cell Cycle Checkpoints; Cell Proliferation; Chromosome Aberrations; Drug Resistance, Neoplasm; Enzyme Activation; Etoposide; Gene Expression Regulation; Gene Knockdown Techniques; Genomic Instability; HEK293 Cells; Histones; Humans; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Rad51 Recombinase

2013
Apoptotic susceptibility to DNA damage of pluripotent stem cells facilitates pharmacologic purging of teratoma risk.
    Stem cells translational medicine, 2012, Volume: 1, Issue:10

    Topics: Animals; Annexin A5; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Cell Differentiation; Cells, Cultured; DNA Damage; Embryoid Bodies; Embryonic Stem Cells; Etoposide; Fibroblasts; Flow Cytometry; Genomic Instability; Inhibitory Concentration 50; Lentivirus; Mice; Mice, Nude; Mutagenicity Tests; Organ Specificity; Pluripotent Stem Cells; Polymerase Chain Reaction; Risk Factors; RNA, Small Interfering; Teratoma; Tumor Suppressor Proteins

2012
Instability of expanded simple tandem repeats is induced in cell culture by a variety of agents: N-Nitroso-N-ethylurea, benzo(a)pyrene, etoposide and okadaic acid.
    Mutation research, 2006, Jun-25, Volume: 598, Issue:1-2

    Topics: Animals; Benzo(a)pyrene; Cell Division; Cell Line; Ethylnitrosourea; Etoposide; Genomic Instability; Mice; Mice, Inbred C3H; Mutagenesis; Mutagens; Okadaic Acid; Polymerase Chain Reaction; Tandem Repeat Sequences

2006
Dangerous entanglements.
    Trends in molecular medicine, 2006, Volume: 12, Issue:6

    Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Transformation, Neoplastic; Chromosome Aberrations; Diketopiperazines; DNA Topoisomerases, Type II; Enzyme Inhibitors; Etoposide; G2 Phase; Genomic Instability; Humans; Piperazines; Regenerative Medicine; Stem Cell Transplantation; Stem Cells; Topoisomerase II Inhibitors

2006
DNA cleavage and Trp53 differentially affect SINE transcription.
    Genes, chromosomes & cancer, 2007, Volume: 46, Issue:3

    Topics: Antineoplastic Agents; Cisplatin; DNA Cleavage; DNA Damage; Etoposide; Genomic Instability; Humans; Paclitaxel; Short Interspersed Nucleotide Elements; Thiobarbiturates; Topoisomerase II Inhibitors; Transcription, Genetic; Tumor Suppressor Protein p53; Up-Regulation; Vincristine

2007