Page last updated: 2024-08-23

etoposide and Experimental Neoplasms

etoposide has been researched along with Experimental Neoplasms in 70 studies

Research

Studies (70)

TimeframeStudies, this research(%)All Research%
pre-199023 (32.86)18.7374
1990's12 (17.14)18.2507
2000's20 (28.57)29.6817
2010's13 (18.57)24.3611
2020's2 (2.86)2.80

Authors

AuthorsStudies
Baguley, BC; Deady, LW; Denny, WA; Rodemann, T; Zhuang, L1
Chang, LC; Goto, M; Hung, HY; Kuo, DH; Kuo, SC; Lee, KH; Liu, YQ; Morris-Natschke, SL; Nan, X; Pan, SL; Qian, K; Teng, CM; Wang, CY; Wang, MJ; Wu, TS; Wu, YC; Yang, JS; Yang, L; Yang, XM; Zhao, XB; Zhao, YL1
Chen, W; Li, Z; Lu, C; Shen, Y; Zhang, M1
Bong Oh, K; Ho Lee, G; Hong, S; Jang, K; Ju Han, H; Kook Lee, S; Kyung Kim, W; Lee, J; Park, HG; Shin, J; Sub Byun, W; Woo Ha, M; Yang, J; Yang, S1
Bist, G; Hwang, SY; Jang, H; Jeon, KH; Kadayat, TM; Kim, S; Kunwar, S; Kwon, Y; Lee, ES; Park, S; Seo, M; Sheen, N; Shrestha, A1
Ding, Z; Hai, Z; Kiran, S; Liang, G; Liu, Y; Wang, L; Zhang, H1
Ashizuka, S; Baba, Y; Harada, A; Hiramatsu, T; Kaji, S; Kanamori, D; Miyaguni, K; Ohki, T; Sugihara, T; Uchida, G; Yoshizawa, J1
Nakagawa, T; Nishimura, R; Ong, SM; Saeki, K; Tanaka, Y; Yamamoto, H; Yoshitake, R1
Dito, G; Girit, E; Humphrey, R; Hunt, JT; Jure-Kunkel, M; Lee, F; Masters, G1
Aleksandrova, LN; Bezborodova, OA; Iakubovskaia, RI; Kovalenko, AL; Nemtsova, ER; Venediktova, IuB1
Akhtar, N; Jaggi, M; Khar, RK; Talegaonkar, S1
Elner, VM; Harbour, JW; Mohney, BG; Musch, DC; Smith, AB; Smith, BD; Smith, SJ1
Broggini, M; Carrassa, L; Crippa, F; Damia, G; Ganzinelli, M; Tavecchio, M1
Aboagye, EO; Arstad, E; Glaser, M; Nguyen, QD; Perumal, M; Smith, G1
Choi, IK; Gao, R; Kaul, SC; Kaur, K; Kim, I; Morrow, G; Ryu, J; Tanguay, RM; Wadhwa, R; Yun, CO1
Bagari, R; Bansal, D; Gulbake, A; Jain, A; Jain, SK; Soni, V1
Du, XL; Liu, H; Qian, WY; Sun, DM; Wang, SL; Zhu, RR1
Cai, C; Dong, W; Fan, D; Niu, Y; Tang, X; Wu, X; Zhang, L1
Bökönyi, G; Horváth, A; Kéri, G; Szende, B1
Chen, LM; Ding, Y; Fu, LW; Liang, YJ; Pan, QC; Xiong, HY; Yang, XP1
Johnson, RS; Katschinski, DM; Mohamed, HG; Nadrowitz, R; Ressel, A; Richter, E; Unruh, A; Wenger, RH1
Kasai, S; Matsue, T; Nishizawa, M; Shiku, H; Torisawa, YS1
Astruc, J; Barret, JM; Chansard, N; Créancier, L; Duchier, C; Hill, BT; Kruczynski, A; Menon, Y; Van Hille, B1
Dwarakanath, BS; Gupta, S; Mathur, R1
Dejligbjerg, M; Hofland, KF; Jensen, LH; Jensen, PB; Kristjansen, PE; Rengtved, P; Sehested, M; Thougaard, AV1
Ka, W; Sun, D; Wen, Z; Xu, X; Yao, W; Zeng, Z; Zhou, S1
Acquaviva, AM; Acquaviva, F; Di Matola, T; di Palma, A; Leone, V; Matarese, G; Ricchi, P1
Apetoh, L; Casares, N; Castedo, M; Ciccosanti, F; Fimia, GM; Ghiringhelli, F; Kroemer, G; Larochette, N; Métivier, D; Mignot, G; Obeid, M; Panaretakis, T; Perfettini, JL; Piacentini, M; Tesniere, A; van Endert, P; Zitvogel, L1
Clarke, C; Smyth, MJ1
Adams, JM; Michalak, EM; Strasser, A; Villunger, A1
Broggini, M; Colombo, T; D'Incalci, M; Erba, E; Morasca, L; Torti, L; Ubezio, P; Vaghi, M1
D'Incalci, M; Erba, E; Morasca, L; Vaghi, M1
Achterrath, W; Niederle, N; Schmoll, HJ1
Curry, ME; Issell, BF; Tihon, C1
Arnold, AM; Whitehouse, JM1
Broggini, M; Colombo, T; D'Incalci, M; Erba, E; Torti, L1
Achterrath, W; Hilgard, P; Niederle, N; Raettig, R1
Hara, K; Iwasaka, T; Matsuo, N; Mvula, M; Nakao, Y; Sugimori, H; Yamasaki, F; Yokoyama, M1
Conti, A; Covacci, V; Maestroni, GJ1
Aoyagi, K; Kobunai, T; Oh-hara, T; Shibata, J; Sugimoto, Y; Terada, T; Tsuruo, T; Utsugi, T; Wierzba, K; Yamada, Y1
Longo, DL; Matsushima, K; Pilaro, AM; Usui, N; Wiltrout, RH1
Rose, WC1
Beijnen, JH; Borst, P; Evers, R; Krimpenfort, P; Mayer, U; Mol, CA; van der Valk, M; van Leusden, MR; Wijnholds, J; Zaman, GJ1
Aoyagi, K; Aoyagi, Y; Asao, T; Okazaki, S; Sano, M; Utsugi, T; Wierzba, K; Yamada, Y1
Ikeda, M; Levine, AJ; Lu, H; Taya, Y1
Hainsworth, JD1
Atassi, G; Chaminade, F; Decaestecker, C; Farinelle, S; Fontaine, J; Gordower, L; Kiss, R; Malonne, H; Saucier, JM1
Gurley, KE; Kemp, CJ; Sun, S1
Beauregard, DA; Brindle, KM; Davletov, B; Loizou, L; Zhao, M1
Krammer, PH; Sartorius, UA1
Asai, T; Baba, K; Irimura, K; Oku, N; Shimizu, K; Takada, M1
Carter, SK; Slavik, M1
Grieder, A; Maurer, R; Stähelin, H1
Adamson, RH; Mead, JA; Sieber, SM1
Henney, JE; Muggia, FM; Rozencweig, M; Von Hoff, DD1
Crooke, ST; Issell, BF1
Kreis, W; Soricelli, A1
Barouh, M; Carpentier, Y; Cattan, A; Cattan, E; Pourny, C2
Barlogie, B; Drewinko, B1
Maca, RD1
al-Achi, A; Herman, TS; Holden, SA; Pfeffer, MR; Teicher, BA1
Friche, E; Hansen, HH; Jensen, PB; Roed, H; Skovsgaard, T; Spang-Thomsen, M; Vindeløv, L1
Colvin, OM; Santos, GW1
Bernal, SD; Cathcart, KN; Holden, SA; Teicher, BA1
Brown, JP; Hellström, I; Hellström, KE; Hirschberg, DL; Saulnier, MG; Schreiber, GJ; Senter, PD1
Aherene, GW; Henneberry, HP; Marks, V1
Bresson, ML; Cattan, A1
Goto, A; Haji, A; Hasegawa, Y; Hattori, N; Morita, M1
Nishikawa, K; Okamoto, K; Seki, T; Shibasaki, C; Takahashi, K; Uchida, T1

Reviews

6 review(s) available for etoposide and Experimental Neoplasms

ArticleYear
Extended-schedule oral etoposide in selected neoplasms and overview of administration and scheduling issues.
    Drugs, 1999, Volume: 58 Suppl 3

    Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Clinical Trials, Phase II as Topic; Drug Administration Schedule; Etoposide; Humans; Neoplasms; Neoplasms, Experimental

1999
Investigational drugs under study by the United States National Cancer Institute.
    Cancer treatment reviews, 1976, Volume: 3, Issue:1

    Topics: Acrylates; Alkylating Agents; Ancitabine; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Chemical Phenomena; Chemistry; Chromomycins; Cisplatin; DNA, Neoplasm; Drug Evaluation, Preclinical; Etoposide; Humans; Ifosfamide; Leukemia L1210; Mice; Mitosis; National Institutes of Health (U.S.); Neoplasms; Neoplasms, Experimental; Razoxane; Tegafur; Teniposide; United States

1976
Pharmacology of antitumor agents from higher plants.
    Cancer treatment reports, 1976, Volume: 60, Issue:8

    Topics: Animals; Antineoplastic Agents, Phytogenic; Aporphines; Camptothecin; Carcinoma, Squamous Cell; Chemical Phenomena; Chemistry; Etoposide; Humans; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymphoid; Maytansine; Melanoma; Naphthoquinones; Nasopharyngeal Neoplasms; Neoplasms; Neoplasms, Experimental; Phenanthrenes; Structure-Activity Relationship; Teniposide; Vinblastine; Vincristine

1976
VM 26 and VP 16-213: a comparative analysis.
    Cancer, 1977, Volume: 40, Issue:1

    Topics: Animals; Brain Neoplasms; Drug Evaluation; Etoposide; Humans; Kinetics; Leukemia; Lung Neoplasms; Lymphoma; Neoplasms, Experimental; Podophyllotoxin; Teniposide; Urinary Bladder Neoplasms

1977
Etoposide (VP-16-213).
    Cancer treatment reviews, 1979, Volume: 6, Issue:2

    Topics: Adult; Animals; Bone Marrow; Cell Cycle; Child; Digestive System; Drug Therapy, Combination; Etoposide; Female; Humans; Leukemia; Lung Neoplasms; Lymphoma; Male; Mice; Neoplasms; Neoplasms, Experimental; Podophyllotoxin; Rats

1979
Pharmacological purging of bone marrow with reference to autografting.
    Clinics in haematology, 1986, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Animals; Bleomycin; Bone Marrow; Bone Marrow Transplantation; Cell Separation; Child; Child, Preschool; Clinical Trials as Topic; Cyclophosphamide; Drug Evaluation; Etoposide; Graft vs Host Disease; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma; Lysophosphatidylcholines; Methylprednisolone; Neoplasms, Experimental; Phospholipid Ethers; Pyrimidinones; Transplantation, Autologous; Transplantation, Isogeneic

1986

Trials

2 trial(s) available for etoposide and Experimental Neoplasms

ArticleYear
[Etoposide VP 16--213)--a podophyllotoxinderivative with high antitumor activity (author's transl)].
    Klinische Wochenschrift, 1981, Nov-02, Volume: 59, Issue:21

    Topics: Animals; Chemical Phenomena; Chemistry; Clinical Trials as Topic; DNA, Neoplasm; Drug Therapy, Combination; Etoposide; Humans; Neoplasms; Neoplasms, Experimental; Podophyllotoxin; RNA, Neoplasm

1981
Pharmacological purging of bone marrow with reference to autografting.
    Clinics in haematology, 1986, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Animals; Bleomycin; Bone Marrow; Bone Marrow Transplantation; Cell Separation; Child; Child, Preschool; Clinical Trials as Topic; Cyclophosphamide; Drug Evaluation; Etoposide; Graft vs Host Disease; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma; Lysophosphatidylcholines; Methylprednisolone; Neoplasms, Experimental; Phospholipid Ethers; Pyrimidinones; Transplantation, Autologous; Transplantation, Isogeneic

1986

Other Studies

63 other study(ies) available for etoposide and Experimental Neoplasms

ArticleYear
Synthesis and cytotoxic activity of carboxamide derivatives of benzo[b][1,6]naphthyridines.
    Journal of medicinal chemistry, 2003, Mar-13, Volume: 46, Issue:6

    Topics: Animals; Antineoplastic Agents; Cell Division; Drug Screening Assays, Antitumor; Humans; Mice; Naphthyridines; Neoplasm Transplantation; Neoplasms, Experimental; Structure-Activity Relationship; Transplantation, Heterologous; Tumor Cells, Cultured

2003
Design, synthesis, mechanisms of action, and toxicity of novel 20(s)-sulfonylamidine derivatives of camptothecin as potent antitumor agents.
    Journal of medicinal chemistry, 2014, Jul-24, Volume: 57, Issue:14

    Topics: Amidines; Animals; Antineoplastic Agents; Apoptosis; Camptothecin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Female; HCT116 Cells; Humans; KB Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Conformation; Neoplasms, Experimental; Structure-Activity Relationship; Sulfonamides; Topoisomerase I Inhibitors

2014
Design and synthesis of 2-phenylnaphthalenoids as inhibitors of DNA topoisomeraseIIα and antitumor agents.
    European journal of medicinal chemistry, 2014, Oct-30, Volume: 86

    Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Proliferation; DNA Topoisomerases, Type II; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Mice; Mice, Nude; Molecular Structure; Naphthalenes; Neoplasms, Experimental; Quantitative Structure-Activity Relationship; Topoisomerase II Inhibitors; Tumor Cells, Cultured

2014
Synthesis and biological activity of selenopsammaplin A and its analogues as antitumor agents with DOT1L inhibitory activity.
    Bioorganic & medicinal chemistry, 2021, 04-01, Volume: 35

    Topics: Animals; Antineoplastic Agents; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Female; Histone-Lysine N-Methyltransferase; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Structure-Activity Relationship

2021
Identification of new halogen-containing 2,4-diphenyl indenopyridin-5-one derivative as a boosting agent for the anticancer responses of clinically available topoisomerase inhibitors.
    European journal of medicinal chemistry, 2022, Jan-05, Volume: 227

    Topics: Animals; Antineoplastic Agents; Cell Proliferation; Cell Survival; DNA; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Halogens; Humans; Indenes; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Poly-ADP-Ribose Binding Proteins; Pyridones; Structure-Activity Relationship; Topoisomerase Inhibitors; Tumor Cells, Cultured

2022
Alkaline phosphatase-triggered assembly of etoposide enhances its anticancer effect.
    Chemical communications (Cambridge, England), 2018, Feb-15, Volume: 54, Issue:15

    Topics: Alkaline Phosphatase; Animals; Antineoplastic Agents, Phytogenic; Body Weight; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Etoposide; HeLa Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Naphthalenes; Neoplasms, Experimental; Oligopeptides; Organophosphorus Compounds; Particle Size; Structure-Activity Relationship

2018
Thalidomide potentiates etoposide-induced apoptosis in murine neuroblastoma through suppression of NF-κB activation.
    Pediatric surgery international, 2018, Volume: 34, Issue:4

    Topics: Animals; Apoptosis; Cell Line, Tumor; DNA, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Mice; Neoplasms, Experimental; Neuroblastoma; NF-kappa B; Phosphorylation; Signal Transduction; Thalidomide; Up-Regulation

2018
Anti-neoplastic effects of topoisomerase inhibitors in canine mammary carcinoma, melanoma, and osteosarcoma cell lines.
    The Japanese journal of veterinary research, 2017, Volume: 65, Issue:1

    Topics: Animals; Antineoplastic Agents; Carcinoma; Cell Line, Tumor; Dog Diseases; Dogs; Etoposide; Female; Mammary Neoplasms, Animal; Melanoma; Mice; Neoplasms, Experimental; Osteosarcoma; Topoisomerase Inhibitors

2017
Synergy between chemotherapeutic agents and CTLA-4 blockade in preclinical tumor models.
    Cancer immunology, immunotherapy : CII, 2013, Volume: 62, Issue:9

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; CTLA-4 Antigen; Deoxycytidine; Drug Synergism; Epothilones; Etoposide; Female; Gemcitabine; Ipilimumab; Mice; Mice, Inbred BALB C; Neoplasms, Experimental

2013
[Experimental study of remaxol as a drug for supportive therapy in traditional and high-dose treatment of tumors].
    Eksperimental'naia i klinicheskaia farmakologiia, 2013, Volume: 76, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Deoxycytidine; Etoposide; Gemcitabine; Methotrexate; Mice; Neoplasms, Experimental; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Succinates

2013
Self-nanoemulsifying lipid carrier system for enhancement of oral bioavailability of etoposide by P-glycoprotein modulation: in vitro cell line and in vivo pharmacokinetic investigation.
    Journal of biomedical nanotechnology, 2013, Volume: 9, Issue:7

    Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line; Cell Line, Tumor; Cell Survival; Emulsions; Etoposide; Humans; Lipids; Male; Nanocapsules; Neoplasms, Experimental; Rats; Rats, Wistar; Treatment Outcome

2013
Preclinical Acute Ocular Safety Study of Combined Intravitreal Carboplatin and Etoposide Phosphate for Retinoblastoma.
    Ophthalmic surgery, lasers & imaging retina, 2017, 02-01, Volume: 48, Issue:2

    Topics: Animals; Antineoplastic Agents; Carboplatin; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroretinography; Etoposide; Intravitreal Injections; Male; Neoplasms, Experimental; Ophthalmoscopy; Organophosphorus Compounds; Rabbits; Retina; Retinal Neoplasms; Retinoblastoma; Treatment Outcome; Visual Acuity

2017
Checkpoint kinase 1 down-regulation by an inducible small interfering RNA expression system sensitized in vivo tumors to treatment with 5-fluorouracil.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Aug-15, Volume: 14, Issue:16

    Topics: Animals; Antineoplastic Agents; Blotting, Western; Boronic Acids; Bortezomib; Cell Cycle; Cell Line, Tumor; Checkpoint Kinase 1; Down-Regulation; Doxorubicin; Etoposide; Female; Fluorescent Antibody Technique; Fluorouracil; Genes, p53; Humans; Immunohistochemistry; Mice; Mice, Nude; Neoplasms, Experimental; Paclitaxel; Protein Kinases; Pyrazines; RNA, Small Interfering; Transfection; Xenograft Model Antitumor Assays

2008
Positron emission tomography imaging of drug-induced tumor apoptosis with a caspase-3/7 specific [18F]-labeled isatin sulfonamide.
    Proceedings of the National Academy of Sciences of the United States of America, 2009, Sep-22, Volume: 106, Issue:38

    Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 7; Cell Line, Tumor; Cisplatin; Cyclophosphamide; Etoposide; Fluorodeoxyglucose F18; Humans; Isatin; Male; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Positron-Emission Tomography; Protein Binding; Radiopharmaceuticals

2009
Proproliferative functions of Drosophila small mitochondrial heat shock protein 22 in human cells.
    The Journal of biological chemistry, 2010, Feb-05, Volume: 285, Issue:6

    Topics: Animals; Antineoplastic Agents; Blotting, Western; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cellular Senescence; Drosophila Proteins; Drug Resistance, Neoplasm; Etoposide; Female; Fibroblasts; Heat-Shock Proteins; Humans; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondrial Proteins; Neoplasms, Experimental; Nocodazole; Paclitaxel; Transfection; Transplantation, Heterologous; Tumor Suppressor Protein p53

2010
Chondroitin sulfate functionalized liposomes for solid tumor targeting.
    Journal of drug targeting, 2011, Volume: 19, Issue:4

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Chondroitin Sulfates; Drug Carriers; Drug Delivery Systems; Etoposide; Female; Humans; Liposomes; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Tissue Distribution

2011
pH-sensitive strontium carbonate nanoparticles as new anticancer vehicles for controlled etoposide release.
    International journal of nanomedicine, 2012, Volume: 7

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Carbonates; Delayed-Action Preparations; Etoposide; Humans; Hydrogen-Ion Concentration; Nanocapsules; Neoplasms, Experimental; Particle Size; Strontium; Treatment Outcome

2012
A stable and practical etoposide-containing intravenous long-/medium-chain triglycerides-based lipid emulsion formulation: pharmacokinetics, biodistribution, toxicity, and antitumor efficacy.
    Expert opinion on drug delivery, 2013, Volume: 10, Issue:5

    Topics: Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Dogs; Drug Carriers; Etoposide; Fat Emulsions, Intravenous; Female; Guinea Pigs; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Experimental; Rabbits; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Tissue Distribution; Triglycerides; Tumor Cells, Cultured

2013
Effect of a novel somatostatin analogue combined with cytotoxic drugs on human tumour xenografts and metastasis of B16 melanoma.
    British journal of cancer, 2003, Jan-13, Volume: 88, Issue:1

    Topics: Animals; Antineoplastic Agents; Dacarbazine; Disease Models, Animal; Drug Therapy, Combination; Etoposide; Humans; Lymphoma; Male; Melanoma, Experimental; Mice; Mice, Inbred CBA; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Peptides, Cyclic; Somatostatin; Xenograft Model Antitumor Assays

2003
[Experimental studies on treatment of nasopharyngeal carcinoma with combination regimen of hydroxycamptothecin and etoposide].
    Ai zheng = Aizheng = Chinese journal of cancer, 2003, Volume: 22, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Survival; Disease Models, Animal; Drug Resistance, Neoplasm; Etoposide; Mice; Mice, Inbred BALB C; Mice, Nude; Nasopharyngeal Neoplasms; Neoplasm Transplantation; Neoplasms, Experimental; Topoisomerase I Inhibitors; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2003
The hypoxia-inducible factor-1 alpha is a negative factor for tumor therapy.
    Oncogene, 2003, May-22, Volume: 22, Issue:21

    Topics: Animals; Antineoplastic Agents; Apoptosis; Carboplatin; Cell Line, Transformed; DNA Repair; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Gene Deletion; Hypoxia-Inducible Factor 1, alpha Subunit; Iron Chelating Agents; Male; Mice; Mice, Nude; Neoplasms, Experimental; Topoisomerase I Inhibitors; Transcription Factors; Tumor Suppressor Protein p53

2003
Proliferation assay on a silicon chip applicable for tumors extirpated from mammalians.
    International journal of cancer, 2004, Mar-20, Volume: 109, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Division; Cisplatin; Collagen; Drug Screening Assays, Antitumor; Electrochemistry; Etoposide; Female; HL-60 Cells; Humans; Mice; Mice, SCID; Microcomputers; Microscopy; Neoplasms, Experimental; Silicon

2004
Decreased nucleotide excision repair activity and alterations of topoisomerase IIalpha are associated with the in vivo resistance of a P388 leukemia subline to F11782, a novel catalytic inhibitor of topoisomerases I and II.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, May-01, Volume: 10, Issue:9

    Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents; Blotting, Northern; Catalysis; Cell Line, Tumor; Cisplatin; DNA Repair; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA-Binding Proteins; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Leukemia; Mice; Mice, Inbred DBA; Mutation, Missense; Naphthalenes; Neoplasm Transplantation; Neoplasms, Experimental; Organophosphorus Compounds; Pyrans; RNA, Messenger; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

2004
The glycolytic inhibitor 2-deoxy-D-glucose enhances the efficacy of etoposide in ehrlich ascites tumor-bearing mice.
    Cancer biology & therapy, 2005, Volume: 4, Issue:1

    Topics: Animals; Antimetabolites; Antineoplastic Agents, Phytogenic; Carcinoma, Ehrlich Tumor; Cell Cycle; Cell Proliferation; Deoxyglucose; DNA Damage; Drug Interactions; Etoposide; Mice; Neoplasms, Experimental

2005
Combining etoposide and dexrazoxane synergizes with radiotherapy and improves survival in mice with central nervous system tumors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Sep-15, Volume: 11, Issue:18

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Central Nervous System Neoplasms; Combined Modality Therapy; DNA Damage; DNA, Neoplasm; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Etoposide; Female; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Razoxane; Survival Analysis; Time Factors; Treatment Outcome; Tumor Cells, Cultured

2005
Alterations in hemorheological properties of erythrocytes in nude mice with erythroleukemia and the treatment effects of etoposide.
    Clinical hemorheology and microcirculation, 2005, Volume: 33, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Blood Viscosity; Erythroblasts; Erythrocytes; Etoposide; Female; Hemorheology; Leukemia, Erythroblastic, Acute; Liver; Male; Mice; Mice, Nude; Neoplasms, Experimental; Spleen

2005
Aspirin reduces the outcome of anticancer therapy in Meth A-bearing mice through activation of AKT-glycogen synthase kinase signaling.
    Molecular cancer therapeutics, 2006, Volume: 5, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Aspirin; Etoposide; Female; Fibrosarcoma; Glycogen Synthase Kinases; Methylcholanthrene; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Time Factors; Tumor Cells, Cultured

2006
Calreticulin exposure dictates the immunogenicity of cancer cell death.
    Nature medicine, 2007, Volume: 13, Issue:1

    Topics: Animals; Anthracyclines; Antigens, Differentiation; Antineoplastic Agents; Apoptosis; Calreticulin; Cell Cycle Proteins; Cell Line, Tumor; Cell Membrane; Colonic Neoplasms; Dendritic Cells; Electrophoresis, Gel, Two-Dimensional; Etoposide; Immunoblotting; Mice; Mice, Inbred BALB C; Mice, Nude; Mitomycin; Neoplasms, Experimental; Phagocytosis; Protein Phosphatase 1; Protein Transport; Recombinant Proteins; RNA Interference

2007
Calreticulin exposure increases cancer immunogenicity.
    Nature biotechnology, 2007, Volume: 25, Issue:2

    Topics: Animals; Anthracyclines; Antigens, Differentiation; Antineoplastic Agents; Apoptosis; Calreticulin; Cell Cycle Proteins; Cell Line, Tumor; Cell Membrane; Colonic Neoplasms; Dendritic Cells; Electrophoresis, Gel, Two-Dimensional; Etoposide; Immunoblotting; Mice; Mice, Inbred BALB C; Mice, Nude; Mitomycin; Neoplasms, Experimental; Phagocytosis; Protein Phosphatase 1; Protein Transport; Recombinant Proteins; RNA Interference

2007
In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute.
    Cell death and differentiation, 2008, Volume: 15, Issue:6

    Topics: Adenovirus E1A Proteins; Animals; Apoptosis; Apoptosis Regulatory Proteins; Cell Transformation, Viral; Etoposide; Fibroblasts; Gamma Rays; Lymphocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; Neoplasms, Experimental; Proto-Oncogene Proteins c-bcl-2; Thymus Gland; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

2008
Flow-cytometric analysis of DNA distribution after VP16-213 treatment of Lewis lung carcinoma.
    Cancer chemotherapy and pharmacology, 1983, Volume: 10, Issue:3

    Topics: Animals; Cell Cycle; Cell Line; DNA, Neoplasm; Etoposide; Flow Cytometry; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms, Experimental; Podophyllotoxin

1983
In vitro cytotoxicity of VP 16 on primary tumor and metastasis of Lewis lung carcinoma.
    European journal of cancer & clinical oncology, 1982, Volume: 18, Issue:4

    Topics: Animals; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Etoposide; Lung Neoplasms; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasms, Experimental; Podophyllotoxin; Thymidine

1982
Etoposide (VP16-213) and teniposide (VM26) comparative in vitro activities in human tumors.
    Cancer chemotherapy and pharmacology, 1982, Volume: 7, Issue:2-3

    Topics: Antineoplastic Agents; Cells, Cultured; Etoposide; Humans; Neoplasms; Neoplasms, Experimental; Podophyllotoxin; Teniposide

1982
Interaction of VP16-213 with the DNA repair antagonist chloroquine.
    Cancer chemotherapy and pharmacology, 1982, Volume: 7, Issue:2-3

    Topics: Animals; Chloroquine; DNA Repair; Drug Interactions; Etoposide; Female; Lymphoma; Mice; Mice, Inbred CBA; Neoplasms, Experimental; Podophyllotoxin; Vincristine

1982
Pharmacokinetics of VP16-213 in Lewis lung carcinoma bearing mice.
    Cancer chemotherapy and pharmacology, 1982, Volume: 7, Issue:2-3

    Topics: Animals; Etoposide; Kinetics; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Podophyllotoxin; Tissue Distribution

1982
Etoposide--chemistry, preclinical and clinical pharmacology.
    Cancer treatment reviews, 1982, Volume: 9 Suppl

    Topics: Animals; Chemical Phenomena; Chemistry; Drug Therapy, Combination; Etoposide; Humans; Kinetics; Neoplasms, Experimental; Podophyllotoxin

1982
Effects of single and combined application of anti-cancer drugs on cervical adenocarcinoma. I. Antitumor activity in vitro.
    Acta obstetricia et gynecologica Scandinavica, 1995, Volume: 74, Issue:5

    Topics: Adenocarcinoma; Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line; Combined Modality Therapy; Etoposide; Female; Humans; In Vitro Techniques; Interferon-gamma; Mice; Mice, Nude; Middle Aged; Mitomycin; Neoplasms, Experimental; Recombinant Proteins; Uterine Cervical Neoplasms

1995
Hematopoietic rescue via T-cell-dependent, endogenous granulocyte-macrophage colony-stimulating factor induced by the pineal neurohormone melatonin in tumor-bearing mice.
    Cancer research, 1994, May-01, Volume: 54, Issue:9

    Topics: Animals; Apoptosis; Bone Marrow; Cyclophosphamide; Etoposide; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Granulocytes; Lung Neoplasms; Melatonin; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Stem Cells; T-Lymphocytes

1994
Antitumor activity of a novel podophyllotoxin derivative (TOP-53) against lung cancer and lung metastatic cancer.
    Cancer research, 1996, Jun-15, Volume: 56, Issue:12

    Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Colonic Neoplasms; DNA, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Nude; Neoplasms, Experimental; Specific Pathogen-Free Organisms; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1996
Antitumor effects of human recombinant interleukin-1 alpha and etoposide against human tumor cells: mechanism for synergism in vitro and activity in vivo.
    Biotherapy (Dordrecht, Netherlands), 1996, Volume: 9, Issue:4

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Synergism; Etoposide; Female; Humans; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Recombinant Proteins; Sialoglycoproteins; Superoxide Dismutase; Superoxides; Tumor Cells, Cultured

1996
Combination chemotherapy involving orally administered etoposide and JM-216 in murine tumor models.
    Cancer chemotherapy and pharmacology, 1997, Volume: 40, Issue:1

    Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Etoposide; Female; Leukemia P388; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms, Experimental; Organoplatinum Compounds

1997
Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein.
    Nature medicine, 1997, Volume: 3, Issue:11

    Topics: Adult; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; ATP-Binding Cassette Transporters; Bone Marrow Cells; Carrier Proteins; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Humans; Inflammation; Leukotriene C4; Membrane Transport Proteins; Mice; Mice, Knockout; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Neoplasms, Experimental; Tumor Cells, Cultured

1997
Antitumor activity of a novel quinoline derivative, TAS-103, with inhibitory effects on topoisomerases I and II.
    Japanese journal of cancer research : Gann, 1997, Volume: 88, Issue:10

    Topics: Adenocarcinoma; Aminoquinolines; Animals; Antineoplastic Agents; Camptothecin; Cisplatin; Colonic Neoplasms; DNA; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Etoposide; Humans; Indenes; Indoles; Irinotecan; Lung Neoplasms; Male; Melanoma; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Pyridines; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1997
Ultraviolet radiation, but not gamma radiation or etoposide-induced DNA damage, results in the phosphorylation of the murine p53 protein at serine-389.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, May-26, Volume: 95, Issue:11

    Topics: Animals; Antineoplastic Agents, Phytogenic; DNA Damage; Etoposide; Gamma Rays; Humans; Male; Mice; Neoplasms, Experimental; Phosphorylation; Serine; Testicular Neoplasms; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Ultraviolet Rays

1998
In vitro and in vivo pharmacological characterizations of the antitumor properties of two new olivacine derivatives, S16020-2 and S30972-1.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:9

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Division; Doxorubicin; Drug Screening Assays, Antitumor; Ellipticines; Etoposide; Female; Humans; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms, Experimental; Topoisomerase II Inhibitors; Tumor Cells, Cultured

2000
p53 induction and apoptosis in response to radio- and chemotherapy in vivo is tumor-type-dependent.
    Cancer research, 2001, Jan-01, Volume: 61, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Crosses, Genetic; DNA Damage; Doxorubicin; Etoposide; Female; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Neoplasms, Experimental; Tumor Suppressor Protein p53; Whole-Body Irradiation

2001
Non-invasive detection of apoptosis using magnetic resonance imaging and a targeted contrast agent.
    Nature medicine, 2001, Volume: 7, Issue:11

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Calcium-Binding Proteins; Cell Membrane; Contrast Media; Etoposide; Ferric Compounds; Flow Cytometry; In Vitro Techniques; Magnetic Resonance Imaging; Magnetics; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Neoplasms, Experimental; Nerve Tissue Proteins; Protein Binding; Protein Structure, Tertiary; Rats; Synaptotagmin I; Synaptotagmins

2001
Upregulation of Bcl-2 is involved in the mediation of chemotherapy resistance in human small cell lung cancer cell lines.
    International journal of cancer, 2002, Feb-10, Volume: 97, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Small Cell; Caspases; Cell Survival; Cisplatin; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Fas Ligand Protein; fas Receptor; Humans; Lung Neoplasms; Membrane Glycoproteins; Mitochondria; Neoplasms, Experimental; Oligonucleotides, Antisense; Phenotype; Proto-Oncogene Proteins c-bcl-2; Transfection; Tumor Cells, Cultured; Up-Regulation

2002
Potential usage of liposomal 4beta-aminoalkyl-4'-O-demethyl-4-desoxypodophyllotoxin (TOP-53) for cancer chemotherapy.
    Biological & pharmaceutical bulletin, 2002, Volume: 25, Issue:6

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Antineoplastic Agents; Blood Vessels; Body Weight; Enzyme Inhibitors; Etoposide; Liposomes; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Survival Analysis; Topoisomerase II Inhibitors

2002
Comparative study of early effects of epipodophyllotoxin derivatives and other cytostatic agents on mastocytoma cultures.
    Cancer research, 1977, Volume: 37, Issue:9

    Topics: Antineoplastic Agents; Bleomycin; Cell Division; Cell Line; Colchicine; Cytarabine; DNA, Neoplasm; Etoposide; Mast-Cell Sarcoma; Mechlorethamine; Mercaptopurine; Methotrexate; Mitosis; Neoplasm Proteins; Neoplasms, Experimental; Podophyllotoxin; Razoxane; RNA, Neoplasm; Teniposide; Vincristine; X-Rays

1977
Comparison of a water-soluble and a water-insoluble podophyllotoxin derivative in murine neoplasms.
    Journal of cancer research and clinical oncology, 1979, Volume: 95, Issue:3

    Topics: Animals; Body Weight; Etoposide; Liver Neoplasms, Experimental; Mice; Neoplasms, Experimental; Podophyllotoxin; Solubility; Water

1979
Effect of hemostasis modifiers of the activity of VP 16 213 on Lewis lung carcinoma.
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1977, Volume: 27, Issue:5

    Topics: Animals; Aspirin; Etoposide; Hemostasis; Heparin; Lung Neoplasms; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Podophyllotoxin; Transplantation, Homologous

1977
Antimetastasis effect of two derivatives of epiposophyllotoxin in mice.
    European journal of cancer, 1976, Volume: 12, Issue:10

    Topics: Animals; Etoposide; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Podophyllotoxin; Solvents; Teniposide; Time Factors

1976
Survival and cycle-progression delay of human lymphoma cells in vitro exposed to VP-16-213.
    Cancer treatment reports, 1976, Volume: 60, Issue:9

    Topics: Cell Division; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Etoposide; Humans; Lymphoma; Neoplasms, Experimental; Podophyllotoxin

1976
Enhancement of etoposide and methotrexate sensitivity by indomethacin in vitro.
    Anti-cancer drug design, 1991, Volume: 6, Issue:5

    Topics: Animals; Bleomycin; Drug Synergism; Etoposide; Humans; Indomethacin; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lipoxygenase Inhibitors; Lung Neoplasms; Lymphoma; Methotrexate; Neoplasms, Experimental; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostaglandins; Protein Kinase Inhibitors; Tumor Cells, Cultured

1991
The interaction of cisplatin plus etoposide with radiation +/- hyperthermia.
    International journal of radiation oncology, biology, physics, 1990, Volume: 19, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Cell Survival; Cisplatin; Combined Modality Therapy; Etoposide; Fibrosarcoma; Flow Cytometry; Hyperthermia, Induced; Male; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Radiotherapy Dosage

1990
Antitumor activity of the two epipodophyllotoxin derivatives VP-16 and VM-26 in preclinical systems: a comparison of in vitro and in vivo drug evaluation.
    Cancer chemotherapy and pharmacology, 1990, Volume: 27, Issue:3

    Topics: Animals; Drug Evaluation; Drug Resistance; Etoposide; Male; Mice; Mice, Inbred DBA; Neoplasms, Experimental; Teniposide; Tumor Stem Cell Assay

1990
Effect of fluosol-DA/carbogen on etoposide/alkylating agent antitumor activity.
    Cancer chemotherapy and pharmacology, 1988, Volume: 21, Issue:4

    Topics: Alkylating Agents; Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carbon Dioxide; Carmustine; Cell Division; Cell Survival; Drug Combinations; Etoposide; Fluorocarbons; Hydroxyethyl Starch Derivatives; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Organoplatinum Compounds; Oxygen

1988
Anti-tumor effects of antibody-alkaline phosphatase conjugates in combination with etoposide phosphate.
    Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:13

    Topics: Alkaline Phosphatase; Animals; Antibodies, Monoclonal; Biotransformation; Colonic Neoplasms; Etoposide; Female; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Pharmaceutical Preparations; Prodrugs; Transplantation, Heterologous; Tumor Cells, Cultured

1988
Immunocytochemical localisation of VP16-213 in normal and malignant tissues.
    Cancer letters, 1987, Oct-30, Volume: 37, Issue:2

    Topics: Animals; Etoposide; Histocytochemistry; Leukemia L1210; Mice; Neoplasms, Experimental; Tissue Distribution

1987
Vitamin A: failure to demonstrate in mice an anti-tumour effect, whether combined with cytotoxic drugs or not.
    Bulletin du cancer, 1986, Volume: 73, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cisplatin; Cyclophosphamide; Etoposide; Female; Leukemia L1210; Leukemia, Experimental; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Neoplasms, Experimental; Teniposide; Vitamin A

1986
[Antitumor effects of a podophyllotoxin derivative, VP 16-213].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1986, Volume: 87, Issue:1

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Etoposide; Female; Injections, Intraperitoneal; Injections, Intravenous; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Podophyllotoxin

1986
[The antitumor activity of intraperitoneally- or orally-administered etoposide in animals and its administration-schedule dependency].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:12

    Topics: Adenocarcinoma; Administration, Oral; Animals; Carcinoma, Ehrlich Tumor; Colonic Neoplasms; Drug Administration Schedule; Etoposide; Female; Leukemia, Experimental; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Podophyllotoxin

1985