Page last updated: 2024-08-23

etoposide and Down Syndrome

etoposide has been researched along with Down Syndrome in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.33)18.7374
1990's3 (10.00)18.2507
2000's14 (46.67)29.6817
2010's12 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shand, JC1
Adachi, JI; Mishima, K; Miyake, Y; Nishikawa, R; Sasaki, A; Suzuki, T1
Eisenman, K; Maloney, KW; Ross, S1
Adachi, S; Goto, H; Horibe, K; Ito, E; Iwamoto, S; Kinoshita, A; Koh, K; Kudo, K; Moritake, H; Nakahata, T; Nakayama, H; Saito, AM; Shimada, A; Taga, T; Takahashi, H; Taki, T; Tawa, A; Terui, K; Toki, T; Tomizawa, D; Watanabe, T1
Bochennek, K; Creutzig, U; Gilfert, J; Hassler, A; Lehrnbecher, T; Perner, C; Reinhardt, D; Schöning, S1
Adachi, S; Arakawa, Y; Funaki, T; Heike, T; Hiramatsu, H; Mizowaki, T; Nodomi, S; Saida, S; Ueno, H; Umeda, K1
Aguilar-Ponce, JL; Chilaca-Rosas, F; Cruz-López, JC; Martínez-Cedillo, J; Molina-Calzada, C; Vidal-Millán, S1
Campana, D; Crews, KR; Downing, JR; Gandhi, VV; Pounds, S; Pui, CH; Raimondi, SC; Razzouk, BI; Ribeiro, RC; Rubnitz, JE; Yang, S1
Britt-Marie, F; Curt, P; Frost, BM; Gudmar, L; Hasle, H; Hellebostad, M; Henrik, H; Josefine, P; Jukka, K; Kanerva, J; Kjeld, S; Lönnerholm, G; Marit, H; Palle, J; Petersson, C; Schmiegelow, K1
Domm, J; Eckrich, MJ; Frangoul, H; Ho, R; Whitlock, JA1
Blasi, F; Castagnaro, L; Crippa, MP; Ferrai, C; Iotti, G; Longobardi, E; Micali, N; Ricciardi, M1
Fujita, K; Fushimi, H; Hosomi, M; Kato, T; Nakazawa, S; Okumi, M; Takezawa, K; Tanigawa, G; Yamaguchi, S; Yoneda, S1
Abe, M; Arai, J; Katayama, N; Kato, K; Kobayashi, C; Koike, K; Mouri, Y; Shiono, J; Tsuchida, M; Yanase, K; Yoshimi, A1
Balci, TB; Berman, JN; Buck, SA; Dellaire, G; Dombkowski, AA; Edwards, H; Ge, Y; Matherly, LH; Taub, JW; Xavier, AC; Xie, C1
Alonzo, TA; Arceci, RJ; Barnard, D; Gamis, AS; Gerbing, RB; Hathaway, L; Hilden, JM; Loew, TW; Ravindranath, Y; Smith, FO; Sorrell, AD; Taub, JW; Woods, WG1
Fujii, M; Goto, H; Ideguchi, M; Nomura, S; Sadahiro, H; Sugimoto, K; Suzuki, M; Yoshikawa, K1
Creutzig, U; Kaiser, J; Klingebiel, T; Lehrnbecher, T; Reinhardt, D; Varwig, D1
Creutzig, U; Diekamp, S; Dworzak, M; Reinhardt, D; Stary, J; Zimmermann, M1
de Graaf, SS; Gibson, BE; Hann, IM; Hills, RK; O'Marcaigh, A; Rao, A; Stiller, C; Webb, DK; Wheatley, K1
Hanada, R; Kigasawa, H; Kinoshita, A; Tabuchi, K; Tomizawa, D; Tsuchida, M; Tsukimoto, I1
Britt-Marie, F; Eva, L; Frost, BM; Göran, G; Gudmar, L; Gustafsson, G; Hellebostad, M; Jukka, K; Kanerva, J; Kjeld, S; Liliemark, E; Lönnerholm, G; Marit, H; Palle, J; Schmiegelow, K1
Hamamoto, K; Hanada, R; Horibe, K; Imaizumi, M; Kigasawa, H; Kobayashi, R; Kojima, S; Kudo, K; Morimoto, A; Nakayama, H; Tabuchi, K; Tawa, A; Tsuchida, M; Tsukimoto, I; Yabe, H1
Alfaro, E; Casak, S; Cygler, A; Felice, MS; Fraquelli, L; Gallego, M; Pérez, LE; Quinteros, R; Sackmann-Muriel, F; Zubizarreta, P1
Readett, D; Richards, M; Vora, AJ; Watmore, A; Welch, J1
Akiyama, Y; Eguchi, M; Hayashi, Y; Hosoi, G; Ishii, E; Kato, K; Koike, K; Kojima, S; Nishimura, S; Ohara, A; Okamura, J; Okimoto, Y; Sako, M; Sato, T; Tsukimoto, I; Ueda, K; Yazaki, M; Yoshikawa, T1
Frost, BM; Gustafsson, G; Larsson, R; Lönnerholm, G; Nygren, P1
Eksborg, S; Frostvik-Stolt, M; Liliemark, E; Lindberg, A; Söderhäll, S1
Creutzig, U; de Vries, E; Hählen, K; Huismans, DR; Janka-Schaub, GE; Jansen, G; Kaspers, GJ; Peters, GJ; Pieters, R; Rots, MG; van Zantwijk, CH; Veerman, AJ; Zwaan, CM1
Abella, E; Alvarado, CS; Chauvenet, A; Dubowy, R; Harris, M; Inoue, S; Krischer, JP; Ravindranath, Y; Ritchey, AK; Wiley, J1
Brecher, ML; Freeman, AI; Green, DM; Sandberg, AA; Simon, JH; Tebbi, CK1

Reviews

4 review(s) available for etoposide and Down Syndrome

ArticleYear
Craniospinal Germinomas in Patient with Down Syndrome Successfully Treated with Standard-Dose Chemotherapy and Craniospinal Irradiation: Case Report and Literature Review.
    World neurosurgery, 2017, Volume: 108

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Central Nervous System Neoplasms; Craniospinal Irradiation; Down Syndrome; Etoposide; Germinoma; Humans; Magnetic Resonance Imaging; Male; Neoplasms, Multiple Primary; Positron-Emission Tomography; Treatment Outcome

2017
[A case of Down's syndrome associated with recurrent testicular tumor treated by chemotherapy successfully: review of 41 cases in Japanese literature].
    Hinyokika kiyo. Acta urologica Japonica, 2010, Volume: 56, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Down Syndrome; Etoposide; Humans; Lymphatic Metastasis; Male; Seminoma; Testicular Neoplasms

2010
Yolk sac tumor of the bilateral basal ganglia in a patient with Down syndrome.
    Brain tumor pathology, 2013, Volume: 30, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Basal Ganglia; Brain Neoplasms; Chemoradiotherapy; Cisplatin; Disease Progression; Down Syndrome; Endodermal Sinus Tumor; Etoposide; Female; Humans; Ifosfamide; Magnetic Resonance Imaging; Paresis; Treatment Outcome

2013
Acute megakaryoblastic leukemia associated with mosaic Down's syndrome.
    Cancer, 1987, Nov-15, Volume: 60, Issue:10

    Topics: Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 17; Clone Cells; Cyclophosphamide; Cytarabine; Down Syndrome; Doxorubicin; Etoposide; Female; Humans; Hydrocortisone; Infant; Leukemia, Megakaryoblastic, Acute; Methotrexate; Mosaicism; Prednisone; Thioguanine; Trisomy

1987

Trials

10 trial(s) available for etoposide and Down Syndrome

ArticleYear
Preserved High Probability of Overall Survival with Significant Reduction of Chemotherapy for Myeloid Leukemia in Down Syndrome: A Nationwide Prospective Study in Japan.
    Pediatric blood & cancer, 2016, Volume: 63, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Down Syndrome; Doxorubicin; Etoposide; Female; Humans; Induction Chemotherapy; Infant; Japan; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Prospective Studies

2016
Infectious Complications in Children With Acute Myeloid Leukemia and Down Syndrome: Analysis of the Prospective Multicenter Trial AML-BFM 2004.
    Pediatric blood & cancer, 2016, Volume: 63, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Down Syndrome; Etoposide; Female; Humans; Idarubicin; Infant; Infections; Leukemia, Myeloid, Acute; Male; Mitoxantrone

2016
Combination of cladribine and cytarabine is effective for childhood acute myeloid leukemia: results of the St Jude AML97 trial.
    Leukemia, 2009, Volume: 23, Issue:8

    Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cladribine; Combined Modality Therapy; Cytarabine; Daunorubicin; Down Syndrome; Drug Administration Schedule; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Infant; Kaplan-Meier Estimate; Leukemia, Myeloid; Myelodysplastic Syndromes; Prognosis; Proportional Hazards Models; Remission Induction; Young Adult

2009
Thioguanine pharmacokinetics in induction therapy of children with acute myeloid leukemia.
    Anti-cancer drugs, 2009, Volume: 20, Issue:1

    Topics: Administration, Oral; Adolescent; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Down Syndrome; Doxorubicin; Drug Administration Schedule; Drug Monitoring; Erythrocytes; Etoposide; Female; Guanine Nucleotides; Humans; Infant; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Registries; Scandinavian and Nordic Countries; Thioguanine; Thionucleotides; Treatment Outcome

2009
Favorable survival maintained in children who have myeloid leukemia associated with Down syndrome using reduced-dose chemotherapy on Children's Oncology Group trial A2971: a report from the Children's Oncology Group.
    Cancer, 2012, Oct-01, Volume: 118, Issue:19

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Down Syndrome; Drug Administration Schedule; Etoposide; Female; Humans; Infant; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Thioguanine; Treatment Outcome

2012
AML patients with Down syndrome have a high cure rate with AML-BFM therapy with reduced dose intensity.
    Leukemia, 2005, Volume: 19, Issue:8

    Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Down Syndrome; Etoposide; Female; Humans; Idarubicin; Infant; Leukemia, Megakaryoblastic, Acute; Leukemia, Myeloid, Acute; Male; Survival Rate; Treatment Outcome

2005
Treatment for myeloid leukaemia of Down syndrome: population-based experience in the UK and results from the Medical Research Council AML 10 and AML 12 trials.
    British journal of haematology, 2006, Volume: 132, Issue:5

    Topics: Adolescent; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Cytogenetic Analysis; Daunorubicin; Down Syndrome; Drug Administration Schedule; Etoposide; Female; Humans; Infant; Leukemia, Myeloid; Leukocyte Count; Male; Mitoxantrone; Thioguanine; Treatment Outcome; United Kingdom

2006
Repetitive cycles of high-dose cytarabine are effective for childhood acute myeloid leukemia: long-term outcome of the children with AML treated on two consecutive trials of Tokyo Children's Cancer Study Group.
    Pediatric blood & cancer, 2007, Volume: 49, Issue:2

    Topics: Acute Disease; Adolescent; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Down Syndrome; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Hydrocortisone; Infant; Infections; Japan; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Methotrexate; Mitoxantrone; Remission Induction; Survival Analysis; Transplantation, Autologous; Transplantation, Homologous; Treatment Outcome; Tretinoin; Vincristine

2007
Prospective study of a pirarubicin, intermediate-dose cytarabine, and etoposide regimen in children with Down syndrome and acute myeloid leukemia: the Japanese Childhood AML Cooperative Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Dec-01, Volume: 25, Issue:34

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Down Syndrome; Doxorubicin; Etoposide; Female; Humans; Infant; Leukemia, Megakaryoblastic, Acute; Male; Prospective Studies; Treatment Outcome

2007
An effective chemotherapeutic regimen for acute myeloid leukemia and myelodysplastic syndrome in children with Down's syndrome.
    Leukemia, 2000, Volume: 14, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cytarabine; Daunorubicin; Disease-Free Survival; Down Syndrome; Etoposide; Female; Humans; Infant; Leukemia, Megakaryoblastic, Acute; Leukemia, Myeloid, Acute; Male; Myelodysplastic Syndromes; Probability; Remission Induction; Survival Rate; Time Factors; Treatment Outcome

2000

Other Studies

16 other study(ies) available for etoposide and Down Syndrome

ArticleYear
Looking up for AML in Down syndrome.
    Blood, 2017, 06-22, Volume: 129, Issue:25

    Topics: Cytarabine; Down Syndrome; Etoposide; Humans; Leukemia, Myeloid, Acute

2017
Successful Use of EPOCH-R in 2 Young Adult Patients With Burkitt Lymphoma and Acute Kidney Injury: A Case Report.
    Journal of pediatric hematology/oncology, 2019, Volume: 41, Issue:6

    Topics: Acute Kidney Injury; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Cyclophosphamide; Down Syndrome; Doxorubicin; Etoposide; Humans; Male; Prednisone; Prognosis; Rituximab; Vincristine

2019
Efficacy of Ifosfamide-Cisplatin-Etoposide (ICE) Chemotherapy for a CNS Germinoma in a Child With Down Syndrome.
    Journal of pediatric hematology/oncology, 2017, Volume: 39, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Basal Ganglia; Cisplatin; Cranial Irradiation; Down Syndrome; Etoposide; Germinoma; Humans; Ifosfamide; Magnetic Resonance Imaging; Male; Neutropenia; Paresis; Remission Induction; Supratentorial Neoplasms

2017
Treatment experiences of testicular cancer in Hispanic patients with Down's syndrome at the National Cancer Institute of Mexico.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2008, Volume: 10, Issue:11

    Topics: Abnormalities, Multiple; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain Neoplasms; Cisplatin; Combined Modality Therapy; Cryptorchidism; Down Syndrome; Etoposide; Fatal Outcome; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Mexico; Neoplasms, Germ Cell and Embryonal; Orchiectomy; Remission Induction; Retroperitoneal Neoplasms; Seminoma; Testicular Neoplasms; Treatment Outcome; Young Adult

2008
Autologous stem cell transplant in a patient with Down syndrome and relapsed Hodgkin lymphoma.
    Pediatric blood & cancer, 2009, Dec-15, Volume: 53, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carmustine; Child; Combined Modality Therapy; Cyclophosphamide; Down Syndrome; Doxorubicin; Etoposide; Granulocyte Colony-Stimulating Factor; Hodgkin Disease; Humans; Ifosfamide; Male; Mesna; Peripheral Blood Stem Cell Transplantation; Prednisone; Procarbazine; Recurrence; Remission Induction; Transplantation Conditioning; Transplantation, Autologous; Vinblastine; Vincristine; Vinorelbine

2009
Down syndrome fibroblasts and mouse Prep1-overexpressing cells display increased sensitivity to genotoxic stress.
    Nucleic acids research, 2010, Volume: 38, Issue:11

    Topics: Animals; Apoptosis; bcl-X Protein; Cells, Cultured; Down Syndrome; Embryonal Carcinoma Stem Cells; Etoposide; Fibroblasts; Genetic Vectors; Homeodomain Proteins; Humans; Mice; Phenotype; Transcription, Genetic; Tumor Suppressor Protein p53; Ultraviolet Rays

2010
Transient abnormal myelopoiesis in a cytogenetically normal neonate.
    International journal of hematology, 2010, Volume: 92, Issue:3

    Topics: Antineoplastic Agents; Cytarabine; Cytogenetic Analysis; Down Syndrome; Etoposide; Exons; GATA1 Transcription Factor; Humans; Infant, Newborn; Karyotyping; Mutation; Myelopoiesis; Myeloproliferative Disorders

2010
A unique role of GATA1s in Down syndrome acute megakaryocytic leukemia biology and therapy.
    PloS one, 2011, Volume: 6, Issue:11

    Topics: Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytarabine; Daunorubicin; Down Syndrome; Down-Regulation; Etoposide; GATA1 Transcription Factor; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Interleukin-1alpha; Lentivirus; Leukemia, Megakaryoblastic, Acute; Megakaryocytes; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering

2011
Infectious complications in pediatric acute myeloid leukemia: analysis of the prospective multi-institutional clinical trial AML-BFM 93.
    Leukemia, 2004, Volume: 18, Issue:1

    Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Bacteria; Child; Child, Preschool; Clinical Trials as Topic; Cytarabine; Down Syndrome; Etoposide; Female; Fever; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Infant; Infant, Newborn; Leukemia, Myeloid; Male; Mitoxantrone; Neutropenia; Prospective Studies; Retrospective Studies; Thioguanine

2004
Etoposide pharmacokinetics in children treated for acute myeloid leukemia.
    Anti-cancer drugs, 2006, Volume: 17, Issue:9

    Topics: Adolescent; Alanine Transaminase; Antineoplastic Agents, Phytogenic; Child; Child, Preschool; Down Syndrome; Etoposide; Female; Humans; Infant; Male; Metabolic Clearance Rate; Precursor Cell Lymphoblastic Leukemia-Lymphoma

2006
Acute myelogenous leukemia in Down's syndrome: report of a single pediatric institution using a BFM treatment strategy.
    Leukemia research, 1998, Volume: 22, Issue:5

    Topics: Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Argentina; Bone Marrow Cells; Child, Preschool; Cytarabine; Down Syndrome; Etoposide; Female; Humans; Idarubicin; Infant; Karyotyping; Leukemia, Myeloid, Acute; Male; Retrospective Studies; Treatment Outcome

1998
Trisomy 21 associated transient neonatal myeloproliferation in the absence of Down's syndrome.
    Archives of disease in childhood. Fetal and neonatal edition, 1998, Volume: 79, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 6; Cytarabine; Down Syndrome; Etoposide; Female; Hematopoietic Stem Cells; Humans; In Situ Hybridization, Fluorescence; Infant, Newborn; Karyotyping; Male; Mitoxantrone; Myeloproliferative Disorders; Time Factors

1998
Cellular cytotoxic drug sensitivity in children with acute leukemia and Down's syndrome: an explanation to differences in clinical outcome?
    Leukemia, 2000, Volume: 14, Issue:5

    Topics: Antineoplastic Agents; Blast Crisis; Cell Survival; Child; Cytarabine; Dexamethasone; Down Syndrome; Doxorubicin; Etoposide; Humans; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thioguanine; Treatment Outcome; Tumor Cells, Cultured

2000
Plasma pharmacokinetics of etoposide (VP-16) after i.v. administration to children.
    Anti-cancer drugs, 2000, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Agents, Phytogenic; Area Under Curve; Child; Child, Preschool; Down Syndrome; Etoposide; Female; Humans; Infant; Injections, Intravenous; Male

2000
Different drug sensitivity profiles of acute myeloid and lymphoblastic leukemia and normal peripheral blood mononuclear cells in children with and without Down syndrome.
    Blood, 2002, Jan-01, Volume: 99, Issue:1

    Topics: Amsacrine; Anthracyclines; Antineoplastic Agents; Busulfan; Cell Survival; Child; Child, Preschool; Cytarabine; Down Syndrome; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Thioguanine; Vincristine

2002
Acute myeloid leukemia (AML) in Down's syndrome is highly responsive to chemotherapy: experience on Pediatric Oncology Group AML Study 8498.
    Blood, 1992, Nov-01, Volume: 80, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Azacitidine; Child; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Daunorubicin; Down Syndrome; Etoposide; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Prednisone; Remission Induction; Thioguanine; Vincristine

1992