etoposide has been researched along with Disease Models, Animal in 93 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (4.30) | 18.7374 |
| 1990's | 9 (9.68) | 18.2507 |
| 2000's | 30 (32.26) | 29.6817 |
| 2010's | 36 (38.71) | 24.3611 |
| 2020's | 14 (15.05) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, GW; Cho, MH; Churchwell, MI; Doerge, DR; Helferich, WG; Hergenrother, PJ; Hoagland, MS; Hwang, SK; Jin, H; Kwon, JT; Pearson, JM; Putt, KS; Sandhorst, JS | 1 |
| Bednarski, PJ; Gastpar, R; Kaufmann, D; Nishino, T; Pojarová, M; Reszka, P; von Angerer, E | 1 |
| Avdeef, A; Tam, KY | 1 |
| Babaev, VM; Belenok, MG; Kataev, VE; Mironov, VF; Rizvanov, IKh; Semenov, VV; Semenova, MN; Strobykina, IY | 1 |
| Avery, VM; Baell, JB; Bullen, HE; Cowman, AF; Crabb, BS; Curtis, JM; Di Rago, AE; Duffy, S; Gilson, PR; Hutton, CA; Jarman, KE; Jousset Subroux, H; Lowes, KN; Nguyen, W; Prinz, B; Sleebs, BE; Tan, C | 1 |
| Feng, Y; Lu, Z; Xu, X; Yang, Y; Zhang, J; Zhang, P; Zhang, T; Zhao, H | 1 |
| Askari, K; Ghalebandi, S; Haghparast, A; Mousavi, Z; Zareie, F | 1 |
| Fukada, J; Hongo, H; Kosaka, T; Mikami, S; Oya, M; Suzuki, Y | 1 |
| Blackhall, F; Bratt, S; Brown, S; Chaturvedi, A; Descamps, T; Dive, C; Frese, KK; Galvin, M; Greenhalgh, M; Hossain, ASMM; Humphrey, S; Kerr, A; Lallo, A; Pearce, SP; Pearsall, S; Priest, L; Revill, M; Schenk, MW; Zhou, C | 1 |
| Gandhi, K; Garg, M; Gota, V; Gurjar, M; Jadhav, SM | 1 |
| Li, Y; Li, Z; Wang, Y; Xu, R; Xu, W; Zhu, X | 1 |
| Bishayi, B; Sultana, S | 1 |
| Chiu, B; Coburn, J; Harrington, K; Ikegaki, N; Kaplan, DL; Shimada, H; Taylor, JS; Wood, L; Yavuz, B; Zeki, J | 1 |
| Borbélyová, V; Celec, P; Chovanec, M; Mego, M; Renczés, E | 1 |
| Annereau, M; Bally, M; Corvis, Y; Fleury, T; Lai-Kuen, R; Lam, A; Martin, B; Mignet, N; Neri, G; Seguin, J | 1 |
| Esperandim, TR; Fernandes, G; Furtado, RA; Nicolella, HD; Ozelin, SD; Ribeiro, AB; Rinaldi-Neto, F; Senedese, JM; Tavares, DC; Veneziani, RCS | 1 |
| Bendau, E; Bruce, JN; Canoll, P; Englander, ZK; Feldstein, NA; Jan, CI; Konofagou, EE; McQuillan, NM; Pouliopoulos, AN; Spinazzi, EF; Tazhibi, M; Upadhyayula, P; Wang, TJC; Wei, HJ; Wu, CC; Yoh, N; Zacharoulis, S | 1 |
| Gan, F; He, Y; Li, S; Luo, M; Luo, P; Xie, B; Zhang, S | 1 |
| Kluska, M; Woźniak, K | 1 |
| Aslani, F; Bergmann, M; Bhushan, S; Elsässer, HP; Fijak, M; Fröhlich, S; Keidel, M; Klug, J; Mahavadi, P; Meinhardt, A; Schuppe, HC; Sebastian, T | 1 |
| Borjihan, G; Cao, X; Fan, L; He, X; Tian, X; Wang, Q; Yan, H; Zhang, L | 1 |
| Chang, KM; Chang, SJ; Chen, TC; Chen, YT; Chuang, YJ; Lai, ZY; Yeo, HY | 1 |
| Allen, CE; Andreassen, PR; Carroll, KR; Chaturvedi, V; Elfers, EE; Greenberg, JN; Henry, MM; Hermiston, ML; Hildeman, DA; Hogan, SP; Jordan, MB; Joyce, M; Kanter, J; Katz, JD; Ladisch, S; Lakes, N; McNally, JP; Millen, SH; Terrell, CE | 1 |
| Ahola, T; An, X; Bai, M; Han, W; Hanski, L; Li, X; Mei, Q; Wu, Z | 1 |
| Akeno, N; Callahan, M; He, D; Kim, RG; Lane, A; Miller, AL; Moulton, JS; Reece, AL; Wikenheiser-Brokamp, KA | 1 |
| Aston, WJ; Hope, DE; Lake, RA; Lesterhuis, WJ; Nowak, AK; Robinson, BW | 1 |
| Aoyagi, T; Kaku, M; Kawakami, K; Oshima, K; Sato, Y; Toyama, M | 1 |
| Chen, Q; Chen, R; Guo, L; Huang, W; Jia, L; Li, Y; Wu, Y; Zhu, Y | 1 |
| Al-Bader, MM; Khan, KM; Kilarkaje, N; Mousa, AM | 1 |
| Calabrese, D; Dietsche, T; Dill, MT; Duong, FH; Heim, MH; Ketterer, S; Makowska, Z; Matter, MS; Terracciano, L | 1 |
| Al-Bader, M; Kilarkaje, N | 1 |
| Fong, BM; Ho, JC; Lam, SK; Li, YY; Mak, JC; Zheng, CY | 1 |
| Hildeman, DA; Johnson, TS; Jordan, MB; Katz, JD; Millen, SH; Terrell, CE | 1 |
| Couez, D; Delneste, Y; Donnou, S; Fremaux, I; Jarry, U; Jeannin, P; Pineau, L; Vincent, M | 1 |
| Amendolara, B; Bansal, M; Bruce, JN; Califano, A; Canoll, P; Carminucci, AS; Karan, C; Lei, L; Leung, R; Li, H; O, J; Realubit, R; Rothcock, R; Showers, C; Sonabend, AM; Yun, J | 1 |
| Baik, H; Bossis, G; Boutzen, H; Brockly, F; Kaoma, T; Kifagi, C; Manenti, S; Pelegrin, M; Piechaczyk, M; Récher, C; Ristic, M; Saland, E; Salem, T; Sarry, JE; Vallar, L; Vergez, F | 1 |
| Acab, A; Chailangkarn, T; Dietrich, A; Fernandez, TV; Griesi-Oliveira, K; Gu, X; Gupta, AR; Haddad, G; Ji, W; Lifton, RP; Marchetto, MC; Ming, GL; Muotri, AR; Murdoch, JD; Nicol, X; Nunez, Y; Passos-Bueno, MR; Pradhan, D; Sanders, SJ; Song, H; Spitzer, N; State, MW; Sunaga, DY; Vadasz, E; Walker, MF | 1 |
| Chai, AP; Mao, RR; Xu, L; Yang, YX; Yu, CL; Zhou, H | 1 |
| Airavaara, M; Anttila, J; Arumäe, U; Eesmaa, A; Galli, E; Hellman, M; Lindholm, P; Mätlik, K; Peränen, J; Permi, P; Saarma, M; Yu, LY | 1 |
| Barco, A; Galea, E; Giménez-Llort, L; Giralt, M; Golbano, A; Hidalgo, J; Jia, P; Jové, M; Masgrau, R; Pardo, L; Portero-Otin, M; Pujol, A; Ruiz, M; Schlüter, A; Valor, LM; Zhao, Z | 1 |
| Beuschlein, F; Bidlingmaier, M; Chiapponi, C; Hantel, C; Jung, S; Luconi, M; Poli, G; Reincke, M; Shapiro, I | 1 |
| Cliffe, AR; Dudley, AC; Hida, K; Klagsbrun, M; Shih, SC | 1 |
| Becker, M; Fichtner, I; Hammer, S; Hoffmann, J; Merk, J; Rolff, J; Sommer, A; Soong, R | 1 |
| Cui, K; Li, D; Wang, W; Wang, Y; Zhao, H; Zhu, Y | 1 |
| Babino, D; Crandall, KM; Gonzalez-Brito, M; Koru-Sengul, T; Kuluz, JW; Landrum, J; Padgett, KR; Petito, CK; Sandberg, DI; Solano, J | 1 |
| Chen, X; Huang, Q; Li, C; Li, J; Liu, X; Qiu, Z; Tian, Y; Wang, Y; Wolf, F; Xie, K; Xu, P; Zhang, D | 1 |
| Fu, J; Hanes, J; Tang, BC; Watkins, DN | 1 |
| Fleming, JM; Ginsburg, E; Meyer, MJ; Miller, TC; Vonderhaar, BK | 1 |
| Brown, GC; Fricker, M; Neher, JJ; Théry, C; Tolkovsky, AM; Zhao, JW | 1 |
| Amini, S; Elgart, G; Jimenez, JJ; Mauro, LM; Schachner, LA; Simon, J; Wikramanayake, TC | 1 |
| Fujita-Hamabe, W; Kishioka, S; Kobori, T; Nakamoto, K; Nawa, A; Nishida, M; Tokuyama, S | 1 |
| Jimenez, JJ; Mauro, LM; Nouri, K; Perez, CI; Schachner, LA; Villasante, AC; Wikramanayake, TC | 1 |
| Bray, IM; Bryan, K; Creevey, L; Davidoff, AM; Fay, J; Lynch, J; Meehan, M; O'Meara, A; Ryan, J; Stallings, RL; Tivnan, A; Tracey, L | 1 |
| Algül, H; Conradt, L; Henrich, A; Krämer, OH; Lesina, M; Reichert, M; Saur, D; Schmid, RM; Schneider, G; Wirth, M | 1 |
| Im, JE; Kee, C; Kim, TE; Sohn, S | 1 |
| Bajtner, E; Holmdahl, R; Jonsson, IM; Tarkowski, A; Verdrengh, M; Zaether, O | 1 |
| Flores, KG; Greer, PK; Hale, LP; McAllister, KA; Wiseman, RW | 1 |
| Bökönyi, G; Horváth, A; Kéri, G; Szende, B | 1 |
| Chen, LM; Ding, Y; Fu, LW; Liang, YJ; Pan, QC; Xiong, HY; Yang, XP | 1 |
| Gude, RP; Nagarsenker, MS; Rao, SG; Sant, VP | 1 |
| Bennaghmouch, A; Hackeng, T; Hofstra, L; Kenis, H; Lindhout, T; Narula, J; Ravassa, S; Reutelingsperger, C | 1 |
| Chang, WH; Chen, YJ; Liao, HF; Lin, CC; Lin, SC; Liu, CY; Shih, SC; Wang, TE; Yang, YC | 1 |
| Tsuruki, T; Yoshikawa, M | 1 |
| Dyer, MA; Egorin, M; Gray, JK; Laurie, NA; Leggas, M; Relling, M; Stewart, C; Zhang, J | 1 |
| Abramjuk, C; Jung, K; Krell, HW; Lein, M; Loening, SA; Rothaug, W | 1 |
| Adhikari, JS; Dwarakanath, BS; Murthy, RR; Reddy, LH; Sharma, RK | 1 |
| Butler, RN; Davidson, GP; Howarth, GS; Tooley, KL | 1 |
| Druker, BJ; Elsea, CR; Fischer, A; Nail, LM; Perrin, NA; Wood, LJ | 1 |
| Azarova, AM; Lau, JY; Lin, CP; Liu, LF; Lyu, YL; Tsai, YC; Wang, JC | 1 |
| Asoh, S; Mori, T; Nakashima-Kamimura, N; Nishimaki, K; Ohta, S | 1 |
| Abschuetz, A; Geibig, R; Kees, T; Nickles, D; Régnier-Vigouroux, A; Spiess, E; Zimmer, H | 1 |
| Blatnik, A; Matheny, RB; Niell, HB; Soloway, MS | 1 |
| Hussein, AM; Peters, WP; Stuart, A | 1 |
| Huang, JD; Leu, BL | 1 |
| Calame, W; Douwes-Idema, AE; Mattie, H; van den Barselaar, MT; van Furth, R | 1 |
| Cattan, AR; Maung, ZT | 1 |
| Collins, LV; Deng, GM; Nilsson, IM; Tarkowski, A; Verdrengh, M | 1 |
| Jia, SF; Kleinerman, ES; Worth, LL | 1 |
| Abdelwahid, E; Pelliniemi, LJ; Pöllänen, P; Salminen, E; Söderström, KO; Sundström, J; Veräjänkorva, E | 1 |
| Fortin, D; McCormick, CI; Neuwelt, EA; Nixon, R; Remsen, LG | 1 |
| Chen, L; Liu, Y | 1 |
| Ghiasi, H; Henderson, G; Inman, M; Jones, C; Nesburn, AB; Perng, GC; Wechsler, SL | 1 |
| Bagge, U; Ekman, T; Johansson, JE; Soussi, B | 1 |
| Hsiao, CL; Huang, JD; Kan, WM; Kuo, JH; Liu, YT; Shieh, CY; Su, SF | 1 |
| Keller, ET; Smith, PC | 1 |
| Feng, F; Peng, X; Zhang, W | 1 |
| Blume, KG; Chao, NJ; Kühl, JS; Sikic, BI | 1 |
| Feun, LG; Gray, K; Loo, TL; Lu, K; Savaraj, N; Wang, C | 1 |
| Calame, W; Mattie, H | 1 |
| Leijh, PC; Linde, I; van Furth, R; van't Wout, JW | 1 |
| Matthias, FR; Mueller, IR; Voss, R | 1 |
| Bailleul, F; Horvath, C; Lévi, F; Mathé, G; Mechkouri, M; Reinberg, A; Roulon, A | 1 |
2 review(s) available for etoposide and Disease Models, Animal
| Article | Year |
|---|---|
Natural Polyphenols as Modulators of Etoposide Anti-Cancer Activity.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biomarkers; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Drug Synergism; Etoposide; Humans; Neoplasms; Polyphenols; Structure-Activity Relationship; Topoisomerase II Inhibitors; Xenograft Model Antitumor Assays | 2021 |
DNA topoisomerase II inhibitors.
Topics: Amsacrine; Antineoplastic Agents; Carcinogens; Disease Models, Animal; Etoposide; Evidence-Based Medicine; Humans; Intestinal Absorption; Mitoxantrone; Neoplasms; Nucleic Acid Synthesis Inhibitors; Research Design; Risk Factors; Teniposide; Tissue Distribution; Topoisomerase II Inhibitors | 2000 |
91 other study(ies) available for etoposide and Disease Models, Animal
| Article | Year |
|---|---|
Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Caspases; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Hydrazones; In Vitro Techniques; Mice; Mice, Nude; Molecular Structure; Piperazines; Signal Transduction; Structure-Activity Relationship; Time Factors; Xenograft Model Antitumor Assays | 2006 |
[(2-Phenylindol-3-yl)methylene]propanedinitriles inhibit the growth of breast cancer cells by cell cycle arrest in G(2)/M phase and apoptosis.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase Inhibitors; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; G2 Phase; Humans; Indoles; Mammary Neoplasms, Experimental; Mice; Molecular Structure; Nitriles; Stereoisomerism; Structure-Activity Relationship; Tubulin | 2007 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Triphenylphosphonium Cations of the Diterpenoid Isosteviol: Synthesis and Antimitotic Activity in a Sea Urchin Embryo Model.
Topics: Animals; Antimitotic Agents; Antineoplastic Agents; Cations; Disease Models, Animal; Diterpenes; Diterpenes, Kaurane; Humans; Mediterranean Sea; Mitochondria; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Organophosphorus Compounds; Sea Urchins; Structure-Activity Relationship | 2015 |
Optimization of 2-Anilino 4-Amino Substituted Quinazolines into Potent Antimalarial Agents with Oral in Vivo Activity.
Topics: Administration, Oral; Animals; Antimalarials; Disease Models, Animal; Mice; Plasmodium falciparum; Quinazolines; Structure-Activity Relationship | 2017 |
Topoisomerase 2 inhibitor etoposide promotes interleukin-10 production in LPS-induced macrophages via upregulating transcription factor Maf and activating PI3K/Akt pathway.
Topics: Animals; Anti-Inflammatory Agents; Cell Line; COVID-19 Drug Treatment; Disease Models, Animal; Down-Regulation; Etoposide; Female; Interleukin-10; Interleukin-6; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-maf; Shock, Septic; Topoisomerase II Inhibitors; Tumor Necrosis Factor-alpha; Up-Regulation | 2021 |
Orexin receptors in the CA1 region of hippocampus modulate the stress-induced antinociceptive responses in an animal model of persistent inflammatory pain.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzoxazoles; CA1 Region, Hippocampal; Cyclophosphamide; Disease Models, Animal; Doxorubicin; Etoposide; Inflammation; Isoquinolines; Male; Microinjections; Naphthyridines; Orexin Receptor Antagonists; Orexin Receptors; Pain; Pain Measurement; Prednisone; Pyridines; Rats, Wistar; Stress, Psychological; Urea; Vincristine | 2022 |
Topoisomerase II alpha inhibition can overcome taxane-resistant prostate cancer through DNA repair pathways.
Topics: Animals; Bridged-Ring Compounds; Cell Line, Tumor; Disease Models, Animal; DNA Repair; DNA Topoisomerases, Type II; Drug Resistance, Neoplasm; Etoposide; Gene Expression; Humans; Immunohistochemistry; Male; Mice; Prostatic Neoplasms; Signal Transduction; Taxoids; Topoisomerase II Inhibitors; Xenograft Model Antitumor Assays | 2021 |
Soluble guanylate cyclase signalling mediates etoposide resistance in progressing small cell lung cancer.
Topics: Animals; Cyclic GMP-Dependent Protein Kinases; Disease Models, Animal; Disease Progression; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice; Neoplastic Cells, Circulating; Nitric Oxide; Nitric Oxide Synthase Type II; Receptors, Notch; Signal Transduction; Small Cell Lung Carcinoma; Soluble Guanylyl Cyclase | 2021 |
Effect of Moderate Malnutrition on the Pharmacokinetics of Etoposide and Vincristine in Freshly Weaned Rats.
Topics: Animals; Child; Child, Preschool; Disease Models, Animal; Etoposide; Humans; Malnutrition; Mice; Neoplasms; Rats; Rats, Sprague-Dawley; Vincristine | 2023 |
MicroRNA-23a-3p improves traumatic brain injury through modulating the neurological apoptosis and inflammation response in mice.
Topics: Animals; Apoptosis; Base Sequence; Brain Injuries, Traumatic; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Down-Regulation; Etoposide; Inflammation; Male; Mice, Inbred C57BL; MicroRNAs; Models, Biological; Neurons; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Signal Transduction; TOR Serine-Threonine Kinases; Up-Regulation | 2020 |
Etoposide-mediated depletion of peripheral blood monocytes post s.aureus infection attenuates septic arthritis by modulating macrophage-derived factors responsible for inflammatory destruction.
Topics: Animals; Arthritis, Infectious; Cartilage; Cytokines; Disease Models, Animal; Etoposide; Macrophages; Male; Mice; Monocytes; Staphylococcal Infections; Staphylococcus aureus | 2020 |
Enhancing sustained-release local therapy: Single versus dual chemotherapy for the treatment of neuroblastoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Delayed-Action Preparations; Disease Models, Animal; Dose-Response Relationship, Drug; Doxorubicin; Drug Delivery Systems; Etoposide; Humans; Mice; Neoplasm Transplantation; Neuroblastoma; Silk; Tumor Cells, Cultured; Vincristine | 2020 |
Transient effects of chemotherapy for testicular cancer on mouse behaviour.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Anxiety Disorders; Behavior, Animal; Bleomycin; Cisplatin; Depressive Disorder; Disease Models, Animal; Etoposide; Male; Memory Disorders; Mice; Testicular Neoplasms | 2020 |
Preparation of parenteral nanocrystal suspensions of etoposide from the excipient free dry state of the drug to enhance in vivo antitumoral properties.
Topics: Animals; Antineoplastic Agents; Biological Availability; Cell Line, Tumor; Disease Models, Animal; Dosage Forms; Drug Compounding; Etoposide; Mice; Nanoparticles; Nanotechnology; Neoplasms; Suspensions | 2020 |
Manool, a diterpene from Salvia officinalis, exerts preventive effects on chromosomal damage and preneoplastic lesions.
Topics: Animals; Anticarcinogenic Agents; Cell Line; Colonic Neoplasms; Cricetinae; Disease Models, Animal; Diterpenes; DNA Damage; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Hydrogen Peroxide; Male; Mice; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagenicity Tests; NF-kappa B; Nitric Oxide; Plant Extracts; Precancerous Conditions; Rats; Rats, Wistar; Salvia officinalis | 2021 |
Focused ultrasound mediated blood-brain barrier opening is safe and feasible in a murine pontine glioma model.
Topics: Animals; Biological Transport; Blood-Brain Barrier; Brain Stem; Brain Stem Neoplasms; Disease Models, Animal; Drug Delivery Systems; Etoposide; Evans Blue; Gadolinium; Glioma; Humans; Magnetic Resonance Imaging; Mice; Pons; Proto-Oncogene Proteins c-sis; PTEN Phosphohydrolase; Tumor Suppressor Protein p53; Ultrasonography | 2021 |
Establishment and characterization of an ovarian yolk sac tumor patient-derived xenograft model.
Topics: Animals; Antineoplastic Agents; Bleomycin; Cisplatin; Disease Models, Animal; Endodermal Sinus Tumor; Etoposide; Female; Heterografts; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Germ Cell and Embryonal; Ovarian Neoplasms; Transplantation, Heterologous; Xenograft Model Antitumor Assays | 2021 |
Resistance to apoptosis and autophagy leads to enhanced survival in Sertoli cells.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Autoimmune Diseases; Autophagy; Caspase 3; Cell Survival; Cisplatin; Cross-Sectional Studies; Cytochromes c; Disease Models, Animal; Etoposide; Fatty Alcohols; Gene Expression Regulation, Developmental; Humans; Infertility, Male; Male; Membrane Potential, Mitochondrial; Orchitis; Primary Cell Culture; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Sertoli Cells; Spermatogenesis; Staurosporine | 2017 |
The synthetic antihyperlipidemic drug potassium piperate selectively kills breast cancer cells through inhibiting G1-S-phase transition and inducing apoptosis.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Etoposide; Female; G1 Phase Cell Cycle Checkpoints; Humans; Hypolipidemic Agents; MCF-7 Cells; Mice; Piperidines; Reactive Oxygen Species; Stress, Physiological; Xenograft Model Antitumor Assays | 2017 |
PI3K inhibitor enhances the cytotoxic response to etoposide and cisplatin in a newly established neuroendocrine cervical carcinoma cell line.
Topics: Animals; Antineoplastic Agents; Apoptosis; Biomarkers; Carcinoma, Neuroendocrine; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Disease Models, Animal; DNA Damage; Drug Synergism; Etoposide; Female; Humans; Mice; Papillomavirus Infections; Phosphoinositide-3 Kinase Inhibitors; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays | 2017 |
Manipulating DNA damage-response signaling for the treatment of immune-mediated diseases.
Topics: Animals; Cell Cycle Checkpoints; Disease Models, Animal; DNA Damage; Drug Evaluation, Preclinical; Encephalomyelitis, Autoimmune, Experimental; Etoposide; Humans; Immune System Diseases; Lymphocyte Activation; Lymphohistiocytosis, Hemophagocytic; Mice; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Multiple Sclerosis; Proto-Oncogene Proteins c-mdm2; Signal Transduction; T-Lymphocytes; Tumor Suppressor Protein p53 | 2017 |
Blockade of the LRP16-PKR-NF-κB signaling axis sensitizes colorectal carcinoma cells to DNA-damaging cytotoxic therapy.
Topics: Animals; Antineoplastic Agents; Carboxylic Ester Hydrolases; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; DNA; Drug Synergism; eIF-2 Kinase; Enzyme Inhibitors; Etoposide; Heterografts; Humans; I-kappa B Kinase; Isothiocyanates; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Neoplasm Transplantation; NF-kappa B; Protein Binding; Signal Transduction; Thiourea; Treatment Outcome | 2017 |
TRP53 Mutants Drive Neuroendocrine Lung Cancer Through Loss-of-Function Mechanisms with Gain-of-Function Effects on Chemotherapy Response.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Disease Models, Animal; Disease Progression; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Lung Neoplasms; Mice; Mice, Inbred C57BL; Neuroendocrine Tumors; Sirolimus; Small Cell Lung Carcinoma; Tumor Suppressor Protein p53 | 2017 |
A systematic investigation of the maximum tolerated dose of cytotoxic chemotherapy with and without supportive care in mice.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Disease Models, Animal; Dose-Response Relationship, Drug; Etoposide; Humans; Maximum Tolerated Dose; Mice; Neoplasms | 2017 |
Etoposide and Corticosteroid Combination Therapy Improves Acute Respiratory Distress Syndrome in Mice.
Topics: Animals; Disease Models, Animal; Drug Combinations; Etoposide; Inflammation; Lipopolysaccharides; Lung; Male; Mice; Mice, Inbred C57BL; Prednisolone; Respiratory Distress Syndrome | 2019 |
[Establishment of A Patient-derived Xenotransplantation Animal Model for Small Cell Lung Cancer and Drug Resistance Model].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Disease Models, Animal; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Interleukin Receptor Common gamma Subunit; Lung Neoplasms; Mice, Inbred BALB C; Mice, Inbred NOD; Mice, Knockout; Mice, SCID; Small Cell Lung Carcinoma; Transplantation, Heterologous; Xenograft Model Antitumor Assays | 2019 |
Antioxidants enhance the recovery of three cycles of bleomycin, etoposide, and cisplatin-induced testicular dysfunction, pituitary-testicular axis, and fertility in rats.
Topics: alpha-Tocopherol; Animals; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Ascorbic Acid; Atrophy; Bleomycin; Blotting, Western; Cisplatin; Cytoprotection; Disease Models, Animal; Drug Combinations; Enzyme-Linked Immunosorbent Assay; Etoposide; Female; Fertility; Hormones; Immunohistochemistry; Male; Pituitary Gland; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Recovery of Function; Selenium; Sperm Count; Sperm Motility; Spermatogenesis; Testicular Diseases; Testis; Time Factors; Transferrin; Zinc | 2013 |
Protein phosphatase 2A promotes hepatocellular carcinogenesis in the diethylnitrosamine mouse model through inhibition of p53.
Topics: Animals; Biopsy; Carcinoma, Hepatocellular; Diethylnitrosamine; Disease Models, Animal; Etoposide; Gene Expression Regulation, Enzymologic; Hepacivirus; Hepatitis B, Chronic; Humans; Liver Neoplasms; Mice; Mice, Inbred C57BL; Mice, Transgenic; Organophosphorus Compounds; Phosphorylation; Protein Phosphatase 2; Tumor Suppressor Protein p53 | 2014 |
Effects of antioxidants on drugs used against testicular cancer-induced alterations in metastasis-associated protein 1 signaling in the rat testis.
Topics: Actins; alpha-Tocopherol; Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Ascorbic Acid; Bleomycin; Cisplatin; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Drug; Etoposide; Histone Deacetylases; Male; Proteins; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Selenium; Signal Transduction; Testicular Neoplasms; Testis; Up-Regulation | 2016 |
Combination of arsenic trioxide and chemotherapy in small cell lung cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Cell Proliferation; Cisplatin; Disease Models, Animal; DNA Damage; Drug Synergism; Etoposide; Female; Glutathione; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Mice; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Oxides; Reactive Oxygen Species; Small Cell Lung Carcinoma; Xenograft Model Antitumor Assays | 2013 |
Etoposide selectively ablates activated T cells to control the immunoregulatory disorder hemophagocytic lymphohistiocytosis.
Topics: Animals; Antigen Presentation; Apoptosis; Dendritic Cells; Disease Models, Animal; DNA-Binding Proteins; Etoposide; Interferon-gamma; Lymphocyte Activation; Lymphocytic choriomeningitis virus; Lymphohistiocytosis, Hemophagocytic; Macrophage Activation; Macrophages; Mice; Mice, Knockout; T-Lymphocytes; Topoisomerase II Inhibitors | 2014 |
Treg depletion followed by intracerebral CpG-ODN injection induce brain tumor rejection.
Topics: Adjuvants, Immunologic; Animals; Antibodies; Antigens, Ly; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Cytokines; Disease Models, Animal; Etoposide; Flow Cytometry; Gene Expression Regulation, Neoplastic; Interleukin-2 Receptor alpha Subunit; Killer Cells, Natural; Lymphoma; Memory Disorders; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; NK Cell Lectin-Like Receptor Subfamily B; Oligodeoxyribonucleotides; T-Lymphocytes, Regulatory; Time Factors; Toll-Like Receptor 9 | 2014 |
Convection-enhanced delivery of etoposide is effective against murine proneural glioblastoma.
Topics: Animals; Antigens, Neoplasm; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Convection; Disease Models, Animal; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Delivery Systems; Etoposide; Glioblastoma; Humans; Mice; Poly-ADP-Ribose Binding Proteins; Survival Analysis; Topoisomerase II Inhibitors | 2014 |
The ROS/SUMO axis contributes to the response of acute myeloid leukemia cells to chemotherapeutic drugs.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cytarabine; Daunorubicin; Disease Models, Animal; Etoposide; Female; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Male; Mice; Mice, Nude; Microarray Analysis; Reactive Oxygen Species; SUMO-1 Protein; U937 Cells; Xenograft Model Antitumor Assays | 2014 |
Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Autistic Disorder; Carboplatin; Cell Differentiation; Cell Line; Cell Proliferation; Cells, Cultured; Child; Disease Models, Animal; Embryo, Mammalian; Etoposide; Gene Expression Regulation; Humans; In Vitro Techniques; Induced Pluripotent Stem Cells; Inhibitory Postsynaptic Potentials; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitoxantrone; Mutation; Neurons; Prednisolone; Signal Transduction; TRPC Cation Channels; TRPC6 Cation Channel | 2015 |
Whole-scale neurobehavioral assessments of photothrombotic ischemia in freely moving mice.
Topics: Analysis of Variance; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Infarction; Brain Ischemia; Disease Models, Animal; Etoposide; Exercise Test; Ifosfamide; Intracranial Thrombosis; Lasers; Locomotion; Male; Methotrexate; Mice; Mice, Inbred Strains; Movement Disorders; Rotarod Performance Test; Wakefulness | 2015 |
Role of two sequence motifs of mesencephalic astrocyte-derived neurotrophic factor in its survival-promoting activity.
Topics: Amino Acid Motifs; Animals; Cell Survival; Cysteine; Disease Models, Animal; Etoposide; Ganglia, Spinal; Golgi Apparatus; Intracellular Space; Mice; Mutation; Nerve Growth Factors; Neuroprotective Agents; Protein Transport; Rats, Sprague-Dawley; Recombinant Proteins; Sequence Deletion; Stroke; Structure-Activity Relationship; Superior Cervical Ganglion | 2015 |
Targeted activation of CREB in reactive astrocytes is neuroprotective in focal acute cortical injury.
Topics: Animals; Arabidopsis Proteins; Astrocytes; Brain Injuries; Cells, Cultured; CREB-Binding Protein; Disease Models, Animal; Etoposide; Female; Gene Expression Profiling; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Inflammation; Male; Meta-Analysis as Topic; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Molecular Chaperones; Neurofilament Proteins | 2016 |
Targeting heterogeneity of adrenocortical carcinoma: Evaluation and extension of preclinical tumor models to improve clinical translation.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Animals; Biomarkers, Tumor; Cell Line, Tumor; Cisplatin; Disease Models, Animal; Doxorubicin; ErbB Receptors; Etoposide; Female; Humans; Ki-67 Antigen; Male; Mitotane; Mucin-1; Neoplasm Transplantation; RNA Splicing Factors; Tumor Cells, Cultured; Young Adult | 2016 |
Attenuated p53 activation in tumour-associated stromal cells accompanies decreased sensitivity to etoposide and vincristine.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Etoposide; Gene Expression; Genes, p53; Humans; Mice; Stromal Cells; Vincristine; Xenograft Model Antitumor Assays | 2008 |
Establishment of patient-derived non-small cell lung cancer xenografts as models for the identification of predictive biomarkers.
Topics: Adenocarcinoma; Adult; Aged; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Carboplatin; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cetuximab; Deoxycytidine; Disease Models, Animal; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Etoposide; Female; Gemcitabine; Gene Expression Profiling; Genes, ras; Humans; Immunoblotting; Lung Neoplasms; Male; Mice; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Middle Aged; Mutation; Oligonucleotide Array Sequence Analysis; Paclitaxel; Polymerase Chain Reaction; Prognosis; Protein Kinase Inhibitors; Quinazolines; Radiation-Sensitizing Agents; Small Cell Lung Carcinoma; Tumor Suppressor Protein p53; Vinblastine; Vinorelbine; Xenograft Model Antitumor Assays | 2008 |
Bushen Ningxin Decoction pharmacological serum promotes the proliferation and suppresses the apoptosis of murine osteoblasts through MAPK pathway.
Topics: Animals; Apoptosis; Bone and Bones; Bone Density Conservation Agents; Cell Proliferation; Disease Models, Animal; Drugs, Chinese Herbal; eIF-2 Kinase; Etoposide; Female; Humans; Magnoliopsida; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Osteoblasts; Osteoporosis, Postmenopausal; Ovariectomy; Phytotherapy | 2009 |
Pharmacokinetic analysis of etoposide distribution after administration directly into the fourth ventricle in a piglet model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Cell Count; Chromatography, High Pressure Liquid; Confidence Intervals; Disease Models, Animal; Etoposide; Fourth Ventricle; Infratentorial Neoplasms; Magnetic Resonance Imaging; Neurologic Examination; Swine; Time Factors | 2010 |
Enhanced pancreatic cancer gene therapy by combination of adenoviral vector expressing c-erb-B2 (Her-2/neu)-targeted immunotoxin with a replication-competent adenovirus or etoposide.
Topics: Adenocarcinoma; Adenoviridae; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Combined Modality Therapy; Disease Models, Animal; Etoposide; Gene Targeting; Genetic Therapy; Genetic Vectors; Humans; Immunotoxins; Male; Mice; Mice, Inbred C57BL; Mice, Nude; Pancreatic Neoplasms; Receptor, ErbB-2; Treatment Outcome; Virus Replication | 2010 |
Enhanced efficacy of local etoposide delivery by poly(ether-anhydride) particles against small cell lung cancer in vivo.
Topics: Animals; Cell Line, Tumor; Decanoic Acids; Dicarboxylic Acids; Disease Models, Animal; Drug Delivery Systems; Etoposide; Female; Humans; Kaplan-Meier Estimate; Kinetics; Lung Neoplasms; Mice; Microscopy, Electron, Scanning; Polyethylene Glycols; Small Cell Lung Carcinoma; Treatment Outcome; Xenograft Model Antitumor Assays | 2010 |
Local regulation of human breast xenograft models.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; DNA Methylation; Estrogens; Etoposide; Female; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Promoter Regions, Genetic; Receptors, Estrogen; Receptors, Progesterone; Transplantation, Heterologous | 2010 |
MFG-E8 mediates primary phagocytosis of viable neurons during neuroinflammation.
Topics: Amino Acid Chloromethyl Ketones; Analysis of Variance; Animals; Animals, Newborn; Annexin A5; Antigens, Surface; bcl-2-Associated X Protein; beta-Galactosidase; Cell Count; Cells, Cultured; Cerebellum; Coculture Techniques; Corpus Striatum; Cytokines; Disease Models, Animal; Encephalitis; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Etoposide; Gene Expression Regulation; Glial Fibrillary Acidic Protein; In Situ Nick-End Labeling; Integrin alphaVbeta3; Lectins; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Milk Proteins; Mutation; Neuroglia; Neurons; Peptides, Cyclic; Phagocytosis; Phosphatidylserines; Phosphopyruvate Hydratase; Rats; Signal Transduction | 2012 |
A novel rat model for chemotherapy-induced alopecia.
Topics: Alopecia; Animals; Antineoplastic Agents; Cyclophosphamide; Disease Models, Animal; Etoposide; Hair Follicle; Rats; Rats, Long-Evans | 2012 |
Etoposide modulates the effects of oral morphine analgesia by targeting the intestinal P-glycoprotein.
Topics: Administration, Oral; Analgesics, Opioid; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cyclosporine; Disease Models, Animal; Drug Administration Schedule; Drug Interactions; Etoposide; Intestinal Mucosa; Male; Mice; Morphine; Pain; Rhodamine 123; Up-Regulation | 2012 |
Low-level laser treatment accelerated hair regrowth in a rat model of chemotherapy-induced alopecia (CIA).
Topics: Alopecia; Animals; Antineoplastic Agents; Cyclophosphamide; Disease Models, Animal; Doxorubicin; Etoposide; Female; Hair; Hair Follicle; Hair Removal; Humans; Low-Level Light Therapy; Male; Mice; Rats; Wound Healing | 2013 |
MicroRNA-204 increases sensitivity of neuroblastoma cells to cisplatin and is associated with a favourable clinical outcome.
Topics: Analysis of Variance; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Cisplatin; Disease Models, Animal; Disease-Free Survival; Down-Regulation; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Membrane Glycoproteins; Mice; Mice, Inbred Strains; Mice, SCID; MicroRNAs; Neuroblastoma; Predictive Value of Tests; Proportional Hazards Models; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Real-Time Polymerase Chain Reaction; Receptor, trkB; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation | 2012 |
Mdm2 inhibitors synergize with topoisomerase II inhibitors to induce p53-independent pancreatic cancer cell death.
Topics: Amino Acid Chloromethyl Ketones; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Line, Tumor; Deoxycytidine; Disease Models, Animal; DNA Damage; Doxorubicin; Drug Synergism; Etoposide; Gemcitabine; Imidazoles; Immunohistochemistry; Immunoprecipitation; Indoles; Mice; Pancreatic Neoplasms; Piperazines; Proto-Oncogene Proteins c-mdm2; Pyrrolidinones; Topoisomerase II Inhibitors | 2013 |
Effect of heat shock protein 72 expression on etoposide-induced cell death of rat retinal ganglion cells.
Topics: Animals; Blotting, Western; Cell Death; Cell Survival; Cells, Cultured; Disease Models, Animal; DNA; Etoposide; Gene Expression Regulation; HSP72 Heat-Shock Proteins; Immunohistochemistry; Rats; Retinal Degeneration; Retinal Ganglion Cells | 2013 |
Total abrogation of collagen II-induced arthritis and the B cell response to type II collagen using suboptimal doses of a topoisomerase II antagonist.
Topics: Animals; Antibodies, Monoclonal; Arthritis, Experimental; Arthritis, Rheumatoid; B-Lymphocytes; Collagen Type II; Disease Models, Animal; Enzyme Inhibitors; Etoposide; Female; Immunization; Interferon-gamma; Interleukin-6; Lymph Nodes; Mice; Mice, Inbred DBA; Topoisomerase II Inhibitors | 2002 |
Thymic model for examining BRCA2 expression and function.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; BRCA2 Protein; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Division; Disease Models, Animal; DNA Damage; DNA Primers; Etoposide; Female; Humans; Mice; Mice, Inbred C57BL; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thymus Gland; Up-Regulation | 2002 |
Effect of a novel somatostatin analogue combined with cytotoxic drugs on human tumour xenografts and metastasis of B16 melanoma.
Topics: Animals; Antineoplastic Agents; Dacarbazine; Disease Models, Animal; Drug Therapy, Combination; Etoposide; Humans; Lymphoma; Male; Melanoma, Experimental; Mice; Mice, Inbred CBA; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Peptides, Cyclic; Somatostatin; Xenograft Model Antitumor Assays | 2003 |
[Experimental studies on treatment of nasopharyngeal carcinoma with combination regimen of hydroxycamptothecin and etoposide].
Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Survival; Disease Models, Animal; Drug Resistance, Neoplasm; Etoposide; Mice; Mice, Inbred BALB C; Mice, Nude; Nasopharyngeal Neoplasms; Neoplasm Transplantation; Neoplasms, Experimental; Topoisomerase I Inhibitors; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2003 |
Sterically stabilized etoposide liposomes: evaluation of antimetastatic activity and its potentiation by combination with sterically stabilized pentoxifylline liposomes in mice.
Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Disease Progression; Drug Therapy, Combination; Etoposide; Female; Liposomes; Lung Neoplasms; Male; Melanoma; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasm Transplantation; Pentoxifylline | 2003 |
Annexin A5 down-regulates surface expression of tissue factor: a novel mechanism of regulating the membrane receptor repertoir.
Topics: Animals; Annexin A5; Apoptosis; Carotid Artery Injuries; Cell Line; Cell Membrane; Disease Models, Animal; Down-Regulation; Endocytosis; Etoposide; Factor VII; Humans; Macrophages; Male; Mice; Phosphatidylserines; Receptors, Cell Surface; Signal Transduction; Tetradecanoylphorbol Acetate; Thromboplastin | 2005 |
Etoposide sensitizes CT26 colorectal adenocarcinoma to radiation therapy in BALB/c mice.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Colorectal Neoplasms; Combined Modality Therapy; Disease Models, Animal; Etoposide; Mice; Mice, Inbred BALB C; Radiotherapy | 2005 |
Orally administered FPRL1 receptor agonist peptide MMK-1 inhibits etoposide-induced alopecia by a mechanism different from intraperitoneally administered MMK-1.
Topics: Administration, Oral; Alopecia; Animals; Cimetidine; Disease Models, Animal; Etoposide; Female; Indomethacin; Injections, Intraperitoneal; Male; Peptides; Pyrilamine; Rats; Receptors, Formyl Peptide; Receptors, Lipoxin | 2006 |
Topotecan combination chemotherapy in two new rodent models of retinoblastoma.
Topics: Animals; Animals, Newborn; Antineoplastic Agents; Apoptosis; Carboplatin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Etoposide; Eye; Humans; Mice; Mice, Knockout; Rats; Retinal Neoplasms; Retinoblastoma; Time Factors; Topotecan; Vincristine; Xenograft Model Antitumor Assays | 2005 |
Enhanced inhibitory effect of the matrix metalloproteinase inhibitor Ro 28-2653 in combination with estramustine and etoposide on the prostate carcinoma in the rat Dunning orthotopic tumor model.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Estramustine; Etoposide; Humans; Injections, Intraperitoneal; Male; Neoplasm Invasiveness; Neoplasm Transplantation; Piperazines; Prostatic Neoplasms; Pyrimidines; Rats; Time Factors; Tissue Inhibitor of Metalloproteinases | 2007 |
Tumoricidal effects of etoposide incorporated into solid lipid nanoparticles after intraperitoneal administration in Dalton's lymphoma bearing mice.
Topics: Animals; Apoptosis; Disease Models, Animal; Etoposide; Lymphoma; Mice; Mice, Inbred BALB C; Micronucleus Tests; Nanostructures; Treatment Outcome | 2006 |
A non-invasive method for detection of intestinal mucositis induced by different classes of chemotherapy drugs in the rat.
Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breath Tests; Camptothecin; Cyclophosphamide; Disease Models, Animal; DNA Topoisomerases, Type I; Doxorubicin; Etoposide; Female; Intestine, Small; Irinotecan; Mucositis; Rats; Sucrase; Sucrose; Topoisomerase I Inhibitors | 2006 |
The cancer chemotherapy drug etoposide (VP-16) induces proinflammatory cytokine production and sickness behavior-like symptoms in a mouse model of cancer chemotherapy-related symptoms.
Topics: Analysis of Variance; Animals; Anorexia; Antineoplastic Agents, Phytogenic; Cachexia; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Monitoring; Etoposide; Fatigue; Female; Interferon-beta; Interleukin-6; Macrophages; Mice; Mice, Inbred C57BL; p38 Mitogen-Activated Protein Kinases; Quality of Life; Sick Role; Sleep Wake Disorders; Statistics, Nonparametric; Tumor Necrosis Factor-alpha | 2006 |
Roles of DNA topoisomerase II isozymes in chemotherapy and secondary malignancies.
Topics: Animals; Antineoplastic Agents; Disease Models, Animal; DNA Damage; DNA Topoisomerases, Type II; Drug Design; Etoposide; Isoenzymes; Melanoma, Experimental; Mice; Mice, Knockout; Neoplasms, Second Primary; Protease Inhibitors; Topoisomerase II Inhibitors | 2007 |
Prevention of chemotherapy-induced alopecia by the anti-death FNK protein.
Topics: Alopecia; Animals; Animals, Newborn; Antineoplastic Agents, Phytogenic; Cell Cycle Proteins; Disease Models, Animal; Dose-Response Relationship, Drug; Etoposide; Hair Follicle; Humans; Injections, Intraperitoneal; Injections, Subcutaneous; Protective Agents; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Recombinant Fusion Proteins; tat Gene Products, Human Immunodeficiency Virus | 2008 |
End-stage dying glioma cells are engulfed by mouse microglia with a strain-dependent efficacy.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cells, Cultured; Disease Models, Animal; Etoposide; Glioma; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microglia; Microscopy, Video; Phagocytosis; Species Specificity; Time Factors | 2008 |
Systemic chemotherapy of murine bladder cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cell Line; Cisplatin; Disease Models, Animal; Dose-Response Relationship, Drug; Etoposide; FANFT; Female; Methotrexate; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Urinary Bladder Neoplasms | 1984 |
Protection against chemotherapy-induced alopecia by cyclosporin A in the newborn rat animal model.
Topics: Administration, Cutaneous; Alopecia; Animals; Animals, Newborn; Antineoplastic Agents; Cyclophosphamide; Cyclosporine; Cytarabine; Disease Models, Animal; Etoposide; Injections, Intraperitoneal; Rats; Rats, Sprague-Dawley | 1995 |
Inhibition of intestinal P-glycoprotein and effects on etoposide absorption.
Topics: Adenylyl Imidodiphosphate; Animals; Antibodies, Monoclonal; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Etoposide; In Vitro Techniques; Infusions, Intravenous; Intestinal Absorption; Intestine, Small; Jejunum; Male; Microvilli; Quinidine; Rats; Rats, Sprague-Dawley | 1995 |
Influence of cytostatic agents on the pulmonary defence of mice infected with Klebsiella pneumoniae and on the efficacy of treatment with ceftriaxone.
Topics: Animals; Antineoplastic Agents; Bronchoalveolar Lavage Fluid; Ceftriaxone; Cyclophosphamide; Disease Models, Animal; Etoposide; Granulocytes; Immunosuppressive Agents; Klebsiella Infections; Klebsiella pneumoniae; Leukopenia; Lung Diseases; Macrophages, Alveolar; Male; Mice; Phagocytosis; Specific Pathogen-Free Organisms | 1994 |
A comparison of a CB17 scid mouse model and the tetrazolium-dye assay using human haematological tumour cell lines.
Topics: Animals; Antineoplastic Agents; Burkitt Lymphoma; Coloring Agents; Daunorubicin; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Female; Humans; Idarubicin; Leukemia, Experimental; Male; Mice; Mice, SCID; Multiple Myeloma; Tetrazolium Salts; Toxicity Tests; Tumor Cells, Cultured | 1996 |
Intra-articularly localized bacterial DNA containing CpG motifs induces arthritis.
Topics: Animals; Arthritis; CpG Islands; Disease Models, Animal; DNA Methylation; DNA, Bacterial; Etoposide; Injections, Intraperitoneal; Interleukin-12; Knee Joint; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Mice, SCID; Oligonucleotides; Synovial Membrane; Tumor Necrosis Factor-alpha; Vertebrates | 1999 |
A nude mouse model of human osteosarcoma lung metastases for evaluating new therapeutic strategies.
Topics: Animals; Antineoplastic Agents; Cytokines; Disease Models, Animal; Doxorubicin; Drug Screening Assays, Antitumor; Etoposide; Humans; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Osteosarcoma; Vinblastine | 1999 |
Effect of etoposide on experimental testicular teratoma in 129/SvJ mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Disease Models, Animal; DNA Fragmentation; Drug Resistance; Etoposide; Immunohistochemistry; Injections, Intraperitoneal; Male; Mice; Mice, Inbred Strains; Teratoma; Testicular Neoplasms | 2000 |
Unexpected neurotoxicity of etoposide phosphate administered in combination with other chemotherapeutic agents after blood-brain barrier modification to enhance delivery, using propofol for general anesthesia, in a rat model.
Topics: Anesthesia, General; Anesthetics, Intravenous; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Disease Models, Animal; Etoposide; Female; Neurotoxicity Syndromes; Organophosphate Poisoning; Organophosphorus Compounds; Propofol; Rats; Rats, Long-Evans | 2000 |
[Protection of hematopoietic cells against toxicity of anticancer agents by transfecting mdr1 gene into bone marrow cells].
Topics: Animals; Antineoplastic Agents; Bone Marrow Cells; Colchicine; Disease Models, Animal; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Genes, MDR; Humans; Mice; Transfection; Vincristine | 2000 |
Region of herpes simplex virus type 1 latency-associated transcript sufficient for wild-type spontaneous reactivation promotes cell survival in tissue culture.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cell Line; Cell Survival; Disease Models, Animal; Etoposide; Eye; Gene Expression Regulation; Herpes Simplex; Herpesvirus 1, Human; Introns; Male; Promoter Regions, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rabbits; RNA, Viral; Sequence Deletion; Transfection; Virus Activation; Virus Latency | 2001 |
Disturbance of purine nucleotide metabolism: a possible early key event in development of intestinal damage induced by chemotherapy.
Topics: Animals; Antineoplastic Agents; Capillary Permeability; Chromatography, High Pressure Liquid; Disease Models, Animal; Drug Evaluation, Preclinical; Energy Metabolism; Enterocytes; Etoposide; Injections, Intraperitoneal; Intestinal Diseases; Intestinal Mucosa; Leukocyte Count; Male; Purine Nucleotides; Rats; Rats, Inbred Lew; Time Factors | 2001 |
Effect of hydroxyzine on the transport of etoposide in rat small intestine.
Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Etoposide; Histamine H1 Antagonists; Hydroxyzine; In Vitro Techniques; Infusions, Intravenous; Intestinal Absorption; Intestine, Small; Jejunum; Male; Microvilli; Quinidine; Rats; Rats, Sprague-Dawley; Time Factors | 2001 |
Anti-interleukin-6 monoclonal antibody induces regression of human prostate cancer xenografts in nude mice.
Topics: Animals; Antibodies, Monoclonal; Apoptosis; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Etoposide; Humans; Immunoglobulin G; Interleukin-6; Male; Mice; Mice, Nude; Prostatic Neoplasms; Time Factors; Transplantation, Heterologous; Tumor Cells, Cultured | 2001 |
[Modulation of human small cell lung cancer cell line GLC4/ADR multidrug resistance in the inhibition of multidrug resistance-associated protein and its antisense].
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Carcinoma, Small Cell; Cell Cycle; Cell Division; Cloning, Molecular; Disease Models, Animal; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Gene Expression; Genes, MDR; Genetic Engineering; Humans; Lung Neoplasms; Mice; Mice, Nude; RNA, Antisense; Tumor Cells, Cultured | 2001 |
Use of etoposide in combination with cyclosporin for purging multidrug-resistant leukemic cells from bone marrow in a mouse model.
Topics: Animals; Bone Marrow; Bone Marrow Purging; Cyclosporine; Disease Models, Animal; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Etoposide; Leukemia, Experimental; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Tumor Cells, Cultured | 1992 |
Pharmacology of intrathecal VP-16-213 in dogs.
Topics: Animals; Carcinoma; Disease Models, Animal; Dogs; Etoposide; Injections, Spinal; Meningeal Neoplasms | 1992 |
Effect of cytostatic agents on the number of alveolar phagocytes and the efficacy of ceftriaxone in an experimental murine lung infection.
Topics: Animals; Bronchoalveolar Lavage Fluid; Ceftriaxone; Cell Count; Cyclophosphamide; Disease Models, Animal; Dose-Response Relationship, Drug; Etoposide; Klebsiella Infections; Klebsiella pneumoniae; Lung Diseases; Male; Mice; Phagocytes; Pulmonary Alveoli | 1991 |
Effect of irradiation, cyclophosphamide, and etoposide (VP-16) on number of peripheral blood and peritoneal leukocytes in mice under normal conditions and during acute inflammatory reaction.
Topics: Animals; Cyclophosphamide; Disease Models, Animal; Etoposide; Granulocytes; Inflammation; Leukocyte Count; Leukocytes; Lymphocytes; Male; Mice; Monocytes; Peritoneal Cavity | 1989 |
Effect of monocytopenia on trauma-induced atherosclerotic lesions in the rabbit ear artery.
Topics: Animals; Arteries; Arteriosclerosis; Disease Models, Animal; Etoposide; Female; Hematocrit; Leukocyte Count; Leukopenia; Monocytes; Prednisolone; Rabbits | 1988 |
Circadian rhythm in tolerance of mice for etoposide.
Topics: Animals; Body Weight; Circadian Rhythm; Disease Models, Animal; Drug Tolerance; Etoposide; Leukocyte Count; Light; Lung Diseases; Male; Mathematics; Mice; Podophyllotoxin | 1985 |