Page last updated: 2024-08-23

etoposide and Colorectal Neoplasms

etoposide has been researched along with Colorectal Neoplasms in 64 studies

Research

Studies (64)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (1.56)	18.7374
1990's	15 (23.44)	18.2507
2000's	21 (32.81)	29.6817
2010's	24 (37.50)	24.3611
2020's	3 (4.69)	2.80

Authors

Authors	Studies
Kurumurthy, C; Narsaiah, B; Pamanji, R; Sambasiva Rao, P; Santhosh Kumar, G; Shanthan Rao, P; Veera Swamy, B; Velatooru, LR; Venkateswara Rao, J	1
Abbott, JM; Abraham, AD; D'Alessandro, A; Esquer, H; Gomez, JD; Gustafson, DL; Hamill, BD; Hansen, KC; LaBarbera, DV; Li, L; Lunghofer, PJ; Messersmith, WA; Nemkov, T; Pike, LA; Ramirez, DA; Rinaldetti, S; Schaack, J; Tomlinson, N; Zhou, Q	1
Banerjee, R; Sarkar, S; Shukla, R; Tanveer Ahmed, M	1
Ahn, J; Baek, JH; Hwang, SG; Kim, EH; Kim, JS; Kim, JY; Lee, CW; Lee, J; Lee, KH; Lee, YJ; Park, JK; Song, JY; Yun, HS	1
Alijas, S; Alonso, MJ; Bouzo, BL; Conejos-Sánchez, I; de la Fuente, M; Jatal, R; Lores, S	1
Ge, Q; He, SF; Liu, LL; Meng, JY; Sun, XX; Wang, M; Wong, WK; Yang, F	1
Ahola, T; An, X; Bai, M; Han, W; Hanski, L; Li, X; Mei, Q; Wu, Z	1
Carew, M; Jaksevicius, A; Mistry, C; Modjtahedi, H; Opara, EI	1
Dong, Q; Gao, H; Huang, A; Jiang, T; Liu, H; Shi, L; Sun, X; Sun, Y; Wang, X; Wu, X	1
Arlt, VM; Feser, K; Indra, R; Mrizova, I; Phillips, DH; Sozeri, O; Stiborova, M; Willis, AJ; Wohak, LE	1
Chan, FK; Dong, YJ; He, XQ; Liang, QY; Ng, SS; Sung, JJ; Wu, CW; Yu, J	1
Gu, T; Hu, Y; Kong, W; Li, Y; Liu, C; Wu, H; Xia, Q; Yu, B; Yu, X; Zhang, H; Zhang, X	1
Gu, W; Gu, Y; He, S; He, Z; Qian, Q; Wan, D; Wang, L; Yi, B	1
Firozian, F; Hassanzadeh, F; Sadeghi-Aliabadi, H; Varshosaz, J	1
Choi, HK; Choi, KC; Choi, Y; Kwak, S; Park, SY; Yoon, HG	1
Fox, JL; Storey, A	1
Abriola, L; Fernandez, RJ; Glazer, PM; Hoyer, D; Hungerford, W; Liu, Y; Merkel, J; Peterson-Roth, E; Pike, LR; Qian, JM; Stachelek, GC	1
Al-Anbaky, QA; Ali, AA; Ali, N; Boman, BM; Fields, JZ; Hassen, S; Kilaparty, SP; Majeed, W	1
Ehrenshaft, M; Kumar, A; Mason, RP; Sinha, BK; Tokar, EJ	1
Chang, DK; Cho, YB; Ha, SY; Hong, SN; Huh, JW; Kim, HC; Kim, ST; Kim, YH; Lee, J; Lee, WY; Park, YA; Park, YS; Yun, SH	1
Bales, J; Dive, C; Hodgkinson, C; Martin-Fernandez, C; Morrow, CJ; Welham, MJ; Welman, A	1
Deutsch, E; Loriot, Y; Mordant, P; Olaussen, KA; Soria, JC	1
Cui, J; Li, J; Sun, RH; Wang, GB	1
Fakih, M; Patta, A	1
Batsuren, D; Jho, EH; Kang, JH; Kang, K; Kim, M; Nho, CW; Oh, SH; Park, KH; Tunsag, J; Yun, JH	1
Bellot, GL; Koh, D; Tan, WH; Tay, LL; Wang, X	1
Han, GS; Wang, JB; Zhang, YC; Zhuang, J	1
Fadlalla, K; Katkoori, V; Manne, U; Mosley, L; Samuel, T; Turner, T	1
Bakhanashvili, M; Bonda, E; Derech-Haim, S; Kadosh, R; Rahav, G; Sredni, B; Teiblum, G	1
Alnemri, ES; Fernandes-Alnemri, T; Hong, S; Hwang, I; Kim, YS; Lee, WK; Lee, YS; Park, S; Yu, JW	1
Diamantis, T; Dimitrakopoulos, A; Gennatas, K; Kosmas, C; Paliaros, P; Papastratis, G; Tsavaris, N; Tsipras, H; Vadiaka, M	1
Gennatas, K; Kosmas, C; Kouraklis, G; Margaris, E; Papastratis, G; Rokana, S; Skopelitis, E; Tsavaris, N; Vadiaka, M; Xila, V; Zografos, G	1
Hagimoto, T; Kanda, M; Maeda, K; Ohshima, K; Okada, M; Sakamoto, A; Sonoda, T; Suzumiya, J; Tamura, K; Wakamatsu, S	1
Liu, WM; Propper, DJ; Scott, KA; Shahin, S	1
Roemer, K; Wagner, S	1
Chang, WH; Chen, YJ; Liao, HF; Lin, CC; Lin, SC; Liu, CY; Shih, SC; Wang, TE; Yang, YC	1
Batey, MA; Calvert, AH; Cowell, IG; Curtin, NJ; Griffin, RJ; Newell, DR; Richardson, CJ; Smith, GC; Thomas, HD; Zhao, Y	1
Orzechowski, A; Pajak, B	1
Kenna, T; Mattarollo, SR; Nicol, AJ; Nieda, M	1
Diebold, J; Epanchintsev, A; Hermeking, H; Jung, P; Lodygin, D; Menssen, A; Rezaei, N; Verdoodt, B	1
Cicconetti, F; Franchi, F; Iascone, C; Ielapi, T; Nigita, G; Pastore, C; Seminara, P	1
Hirohashi, S; Honda, K; Huang, L; Ono, M; Satow, R; Shitashige, M; Tomida, A; Tsuruo, T; Yamada, T; Yun, J	1
Alimirah, F; Chen, J; Choubey, D; Ho, SM; Panchanathan, R; Zhang, X	1
Csoka, K; Larsson, R; Liliemark, J; Nygren, P	1
Barni, S; Frontini, L; Labianca, R; Luporini, G; Marini, G; Pancera, G; Zaniboni, A	1
Campbell, K; Huberman, M; Posner, M; Stuart, K	1
Abbruzzese, JL; Ajani, JA; Daugherty, K; Markowitz, AB; Patt, YZ	1
Acimovic, L; Jeremic, B; Mijatovic, L	1
Hidaka, K; Hirohashi, Y; Hisatsugu, T; Kohno, K; Kuwano, M; Sato, S	1
de Boer-Dennert, M; Planting, AS; Stoter, G; van den Bent, MJ; van der Burg, ME; Verweij, J	1
Hausamen, TU; Loeffler, TM	1
Aebi, S; Fink, D; Haas, M; Howell, SB; Kim, HK; Nebel, S; Norris, PS	1
Rowinsky, EK; Siu, LL	1
Aebi, S; Fink, D; Fink, JL; Gordon, R; Howell, SB; Kim, HK; Zheng, H	1
Boisdron-Celle, M; Boulanger, N; Gamelin, E	1
Beviacqua, M; Bordenave, RH; Novellino, PS; Rumi, LS; Trejo, YG	1
Arrigo, AP; Bruey, JM; Fromentin, A; Garrido, C; Hilpert, S; Paul, C; Solary, E	1
Herman, ZS; Machalski, M; Scieszka, M; Zielinski, M	1
Aguado, M; Fallik, D; Jacob, S; Praz, F	1
Aiba, K; Akaza, H; Blackledge, G; Boku, N; Ikeda, T; Isonishi, S; Kato, M; Kawai, K; Mikami, O; Ohashi, Y; Saeki, T; Saijo, N; Sone, S; Stribling, D; Tsukagoshi, S; Tsuruo, T	1
Boven, E; De Vries, R; Haisma, HJ; Pinedo, HM; van Muijen, M	1
Bisagni, G; Boni, C; Ceci, G; Cocconi, G; Di Blasio, B; Passalacqua, R	1
Browne, MJ; Calabresi, P; Clark, JW; Cummings, FJ; Curt, G; Posner, M; Slapak, CA; Urba, S; Weitberg, A; Wiemann, M	1
Beitz, J; Cummings, F; Posner, MR; Weitberg, AB; Zelkowitz, RS	1

Reviews

2 review(s) available for etoposide and Colorectal Neoplasms

Article	Year
Are RAS mutations predictive markers of resistance to standard chemotherapy? Nature reviews. Clinical oncology, 2009, Volume: 6, Issue:9 Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Cisplatin; Clinical Trials, Phase III as Topic; Clinical Trials, Phase IV as Topic; Colorectal Neoplasms; Combined Modality Therapy; Drug Resistance, Neoplasm; Drug Therapy; Etoposide; Genes, ras; Humans; Ifosfamide; Lung Neoplasms; Mitomycin; Mutation; Predictive Value of Tests; Prognosis; Survival Analysis; Treatment Outcome	2009
[Pharmacokinetic monitoring]. Bulletin du cancer, 2000, Volume: 87, Issue:1 Topics: Antineoplastic Agents; Body Mass Index; Camptothecin; Colorectal Neoplasms; Drug Interactions; Drug Monitoring; Etoposide; Fluorouracil; Humans; Irinotecan; Liver; Paclitaxel; Topotecan	2000

Article

Year

Are RAS mutations predictive markers of resistance to standard chemotherapy?

Nature reviews. Clinical oncology, 2009, Volume: 6, Issue:9

Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Cisplatin; Clinical Trials, Phase III as Topic; Clinical Trials, Phase IV as Topic; Colorectal Neoplasms; Combined Modality Therapy; Drug Resistance, Neoplasm; Drug Therapy; Etoposide; Genes, ras; Humans; Ifosfamide; Lung Neoplasms; Mitomycin; Mutation; Predictive Value of Tests; Prognosis; Survival Analysis; Treatment Outcome

2009

[Pharmacokinetic monitoring].

Bulletin du cancer, 2000, Volume: 87, Issue:1

Topics: Antineoplastic Agents; Body Mass Index; Camptothecin; Colorectal Neoplasms; Drug Interactions; Drug Monitoring; Etoposide; Fluorouracil; Humans; Irinotecan; Liver; Paclitaxel; Topotecan

2000

Trials

10 trial(s) available for etoposide and Colorectal Neoplasms

Article	Year
Etoposide added to weekly leucovorin (LV)/5-fluorouracil (5-FU) in LV/5-FU pre-treated patients with advanced colorectal cancer. Medical science monitor : international medical journal of experimental and clinical research, 2002, Volume: 8, Issue:9 Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Etoposide; Fluorouracil; Humans; Leucovorin; Time Factors; Treatment Outcome	2002
Etoposide, leucovorin (LV) and 5-fluorouracil (5-FU) in 5-FU+LV pre-treated patients with advanced colorectal cancer. Journal of chemotherapy (Florence, Italy), 2002, Volume: 14, Issue:4 Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Disease Progression; Etoposide; Feasibility Studies; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoplasm Staging; Safety; Salvage Therapy; Survival Rate	2002
Mitomycin C and etoposide in advanced colorectal carcinoma. A clinical and in vitro experience that focuses the problem of schedule dependence in combination therapy. Chemotherapy, 2007, Volume: 53, Issue:3 Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma; Cell Cycle; Cell Line, Tumor; Colorectal Neoplasms; Etoposide; Female; Humans; Male; Middle Aged; Mitomycin	2007
Oral etoposide as second-line chemotherapy for colorectal cancer: a GISCAD study. Gruppo Italiano Studio Carcinomi Apparato Digerente. Journal of chemotherapy (Florence, Italy), 1995, Volume: 7, Issue:3 Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Colorectal Neoplasms; Etoposide; Female; Humans; Male; Middle Aged	1995
Cisplatin and chronic oral etoposide as salvage therapy for advanced colorectal carcinoma. American journal of clinical oncology, 1995, Volume: 18, Issue:4 Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colorectal Neoplasms; Drug Administration Schedule; Etoposide; Female; Humans; Infusions, Intravenous; Male; Salvage Therapy; Survival Analysis	1995
Phase II study of etoposide and alpha-interferon in patients with advanced measurable colorectal carcinoma. Investigational new drugs, 1993, Volume: 11, Issue:1 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Synergism; Etoposide; Female; Humans; Interferon-alpha; Male; Middle Aged; Neoplasm Metastasis	1993
Carboplatin and etoposide in advanced colorectal carcinoma. A phase II study. Cancer, 1993, May-01, Volume: 71, Issue:9 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Colorectal Neoplasms; Drug Administration Schedule; Etoposide; Female; Humans; Male; Middle Aged; Neoplasm Staging	1993
Phase II study of a short course of weekly high-dose cisplatin combined with long-term oral etoposide in metastatic colorectal cancer. British journal of cancer, 1996, Volume: 73, Issue:10 Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Female; Humans; Male; Middle Aged; Neoplasm Metastasis	1996
High-dose infusional 5-fluorouracil combination therapy of metastatic gastric and colorectal cancer. The Journal of infusional chemotherapy, 1996,Summer, Volume: 6, Issue:3 Topics: Adult; Aged; Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dose-Response Relationship, Drug; Etoposide; Female; Fluorouracil; Humans; Infusions, Intravenous; Interferon-alpha; Leucovorin; Male; Middle Aged; Stomach Neoplasms; Survival Rate; Treatment Outcome	1996
Cisplatin containing chemotherapy influences HLA-DR expression on monocytes from cancer patients. Journal of experimental & clinical cancer research : CR, 1999, Volume: 18, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colorectal Neoplasms; Etoposide; Fluorouracil; HLA-DR Antigens; Humans; Lung Neoplasms; Male; Middle Aged; Monocytes; Reference Values	1999

Other Studies

52 other study(ies) available for etoposide and Colorectal Neoplasms

Article	Year
Synthesis of novel alkyltriazole tagged pyrido[2,3-d]pyrimidine derivatives and their anticancer activity. European journal of medicinal chemistry, 2011, Volume: 46, Issue:8 Topics: Alkylation; Antineoplastic Agents; Azides; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Cyclization; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Leukemia, Monocytic, Acute; Lymphoma; Pyrimidines; Structure-Activity Relationship; Triazoles	2011
Drug Design Targeting T-Cell Factor-Driven Epithelial-Mesenchymal Transition as a Therapeutic Strategy for Colorectal Cancer. Journal of medicinal chemistry, 2019, 11-27, Volume: 62, Issue:22 Topics: Adenosine Triphosphate; Animals; Binding, Competitive; Cell Line, Tumor; Colorectal Neoplasms; DNA Topoisomerases, Type II; Drug Design; Drug Screening Assays, Antitumor; Epithelial-Mesenchymal Transition; Humans; Mice; Molecular Targeted Therapy; Poly-ADP-Ribose Binding Proteins; Structure-Activity Relationship; TCF Transcription Factors; Topoisomerase II Inhibitors; Transcription, Genetic	2019
Etoposide-Entrapped Progesterone-Cationic Lipid Nanoaggregates as Selective Therapeutics against Etoposide-Resistant Colorectal Cancer Cells. Chembiochem : a European journal of chemical biology, 2023, 06-15, Volume: 24, Issue:12 Topics: Animals; Colorectal Neoplasms; Etoposide; HEK293 Cells; Humans; Lipids; Mice; Progesterone	2023
Kinesin light chain 4 as a new target for lung cancer chemoresistance via targeted inhibition of checkpoint kinases in the DNA repair network. Cell death & disease, 2020, 05-26, Volume: 11, Issue:5 Topics: Apoptosis; Cell Line, Tumor; Checkpoint Kinase 1; Checkpoint Kinase 2; Cisplatin; Colorectal Neoplasms; DNA Damage; DNA Repair; DNA-Activated Protein Kinase; Down-Regulation; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Gene Silencing; Humans; Kinesins; Lung Neoplasms; Microtubule-Associated Proteins; Molecular Targeted Therapy; Signal Transduction	2020
Sphingomyelin nanosystems loaded with uroguanylin and etoposide for treating metastatic colorectal cancer. Scientific reports, 2021, 08-26, Volume: 11, Issue:1 Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Drug Delivery Systems; Etoposide; Female; Humans; Mice, Inbred Strains; Mice, Nude; Microscopy, Electron, Scanning; Nanoparticles; Natriuretic Peptides; Neoplasm Metastasis; Particle Size; Receptors, Guanylate Cyclase-Coupled; Sphingomyelins; Tumor Burden; Xenograft Model Antitumor Assays	2021
Potential role of ZEB1 as a DNA repair regulator in colorectal cancer cells revealed by cancer-associated promoter profiling. Oncology reports, 2017, Volume: 38, Issue:4 Topics: Apoptosis; Cell Line, Tumor; Cisplatin; Colorectal Neoplasms; DNA Damage; DNA Helicases; DNA Repair; DNA-Binding Proteins; Endopeptidases; Etoposide; Gene Knockdown Techniques; Homeodomain Proteins; Humans; Promoter Regions, Genetic; RNA, Messenger; Zinc Finger E-box-Binding Homeobox 1	2017
Blockade of the LRP16-PKR-NF-κB signaling axis sensitizes colorectal carcinoma cells to DNA-damaging cytotoxic therapy. eLife, 2017, 08-18, Volume: 6 Topics: Animals; Antineoplastic Agents; Carboxylic Ester Hydrolases; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; DNA; Drug Synergism; eIF-2 Kinase; Enzyme Inhibitors; Etoposide; Heterografts; Humans; I-kappa B Kinase; Isothiocyanates; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Neoplasm Transplantation; NF-kappa B; Protein Binding; Signal Transduction; Thiourea; Treatment Outcome	2017
Inhibitory Effects of Culinary Herbs and Spices on the Growth of HCA-7 Colorectal Cancer Cells and Their COX-2 Expression. Nutrients, 2017, Sep-21, Volume: 9, Issue:10 Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Etoposide; G1 Phase Cell Cycle Checkpoints; Humans; Plants, Medicinal; Poly(ADP-ribose) Polymerases; Spices; Time Factors	2017
Silencing Artemis Enhances Colorectal Cancer Cell Sensitivity to DNA-Damaging Agents. Oncology research, 2018, Dec-27, Volume: 27, Issue:1 Topics: Bleomycin; Camptothecin; Cell Line, Tumor; Colorectal Neoplasms; DNA Damage; DNA End-Joining Repair; DNA-Binding Proteins; Endonucleases; Etoposide; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Nuclear Proteins; Radiation Tolerance; Radiation, Ionizing; Treatment Outcome	2018
The impact of chemotherapeutic drugs on the CYP1A1-catalysed metabolism of the environmental carcinogen benzo[a]pyrene: Effects in human colorectal HCT116 TP53(+/+), TP53(+/-) and TP53(-/-) cells. Toxicology, 2018, 04-01, Volume: 398-399 Topics: Activation, Metabolic; Benzo(a)pyrene; Carcinogens; Cell Survival; Cisplatin; Colorectal Neoplasms; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP3A; DNA Adducts; DNA Damage; Ellipticines; Enzyme Induction; Etoposide; Genes, p53; HCT116 Cells; Humans; Tumor Suppressor Protein p53	2018
MicroRNA-18a attenuates DNA damage repair through suppressing the expression of ataxia telangiectasia mutated in colorectal cancer. PloS one, 2013, Volume: 8, Issue:2 Topics: 3' Untranslated Regions; Aged; Aged, 80 and over; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Base Pairing; Base Sequence; Cell Cycle Proteins; Cell Line, Tumor; Colorectal Neoplasms; DNA Breaks, Double-Stranded; DNA Damage; DNA-Binding Proteins; Etoposide; Female; Gene Expression Regulation, Neoplastic; Humans; Male; MicroRNAs; Middle Aged; Neoplasm Staging; Protein Serine-Threonine Kinases; RNA Interference; Tumor Suppressor Proteins	2013
Sphere formation assay is not an effective method for cancer stem cell derivation and characterization from the Caco-2 colorectal cell line. Current stem cell research & therapy, 2014, Volume: 9, Issue:2 Topics: Animals; Antineoplastic Agents; ATP-Binding Cassette Transporters; Biomarkers, Tumor; Caco-2 Cells; Carcinogenesis; Cell Proliferation; Cell Separation; Cell Survival; Colorectal Neoplasms; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Inhibitory Concentration 50; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Transplantation; Neoplastic Stem Cells; Organoplatinum Compounds; Oxaliplatin; Spheroids, Cellular	2014
Ambra1 is an essential regulator of autophagy and apoptosis in SW620 cells: pro-survival role of Ambra1. PloS one, 2014, Volume: 9, Issue:2 Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Etoposide; Humans; Membrane Proteins; Staurosporine; Up-Regulation	2014
Uptake of etoposide in CT-26 cells of colorectal cancer using folate targeted dextran stearate polymeric micelles. BioMed research international, 2014, Volume: 2014 Topics: Binding, Competitive; Cell Death; Cell Line, Tumor; Colorectal Neoplasms; Dextrans; Etoposide; Fluorescence; Folic Acid; Humans; Inhibitory Concentration 50; Micelles; Microscopy, Electron, Transmission; Polymers; Proton Magnetic Resonance Spectroscopy; Spectroscopy, Fourier Transform Infrared; Stearates	2014
Deubiquitinase OTUD5 mediates the sequential activation of PDCD5 and p53 in response to genotoxic stress. Cancer letters, 2015, Feb-01, Volume: 357, Issue:1 Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Colorectal Neoplasms; DNA Damage; Endopeptidases; Etoposide; Gene Knockdown Techniques; HCT116 Cells; Humans; Lung Neoplasms; Mice; Neoplasm Proteins; Signal Transduction; Stress, Physiological; Transcriptional Activation; Transfection; Tumor Suppressor Protein p53; Ubiquitination	2015
BMX Negatively Regulates BAK Function, Thereby Increasing Apoptotic Resistance to Chemotherapeutic Drugs. Cancer research, 2015, Apr-01, Volume: 75, Issue:7 Topics: Antineoplastic Agents; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Breast Neoplasms; Camptothecin; Cell Line, Tumor; Colorectal Neoplasms; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Male; Phosphorylation; Prostatic Neoplasms; Protein Processing, Post-Translational; Protein Tyrosine Phosphatases, Non-Receptor; Protein-Tyrosine Kinases	2015
YU238259 Is a Novel Inhibitor of Homology-Dependent DNA Repair That Exhibits Synthetic Lethality and Radiosensitization in Repair-Deficient Tumors. Molecular cancer research : MCR, 2015, Volume: 13, Issue:10 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Bone Neoplasms; Cell Line, Tumor; Circular Dichroism; Colorectal Neoplasms; DNA Breaks, Double-Stranded; DNA Repair; Drug Synergism; Etoposide; Glioma; High-Throughput Screening Assays; Humans; Intercalating Agents; Mice; Mice, Nude; Molecular Structure; Neoplasms; Osteosarcoma; Poly(ADP-ribose) Polymerase Inhibitors; Radiation-Sensitizing Agents; Small Molecule Libraries; Sulfonamides; Xenograft Model Antitumor Assays	2015
Interdependence of DNA mismatch repair proteins MLH1 and MSH2 in apoptosis in human colorectal carcinoma cell lines. Molecular and cellular biochemistry, 2016, Volume: 412, Issue:1-2 Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Apoptosis; Caspase 3; Colorectal Neoplasms; DNA Mismatch Repair; Etoposide; Humans; MutL Protein Homolog 1; MutS Homolog 2 Protein; Nuclear Proteins; Proteolysis	2016
Nitric oxide inhibits topoisomerase II activity and induces resistance to topoisomerase II-poisons in human tumor cells. Biochimica et biophysica acta, 2016, Volume: 1860, Issue:7 Topics: Breast Neoplasms; Catalysis; Colorectal Neoplasms; DNA; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Enzyme Stability; Etoposide; Female; HT29 Cells; Humans; MCF-7 Cells; Nitric Oxide; Nitric Oxide Donors; Nucleic Acid Conformation; Protein Conformation; Topoisomerase II Inhibitors	2016
The Clinicopathologic Features and Treatment of 607 Hindgut Neuroendocrine Tumor (NET) Patients at a Single Institution. Medicine, 2016, Volume: 95, Issue:19 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Neuroendocrine; Cisplatin; Colorectal Neoplasms; Disease-Free Survival; Endoscopy, Digestive System; Etoposide; Female; Humans; Male; Middle Aged; Neuroendocrine Tumors; Octreotide; Retrospective Studies; Survival Rate; Treatment Outcome; Young Adult	2016
Blocking phosphoinositide 3-kinase activity in colorectal cancer cells reduces proliferation but does not increase apoptosis alone or in combination with cytotoxic drugs. Molecular cancer research : MCR, 2009, Volume: 7, Issue:6 Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Growth Processes; Cloning, Molecular; Colorectal Neoplasms; Enzyme Inhibitors; Etoposide; Female; HCT116 Cells; HT29 Cells; Humans; Mice; Mutation; Organoplatinum Compounds; Oxaliplatin; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Subunits; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Signal Transduction	2009
[Role of CCL21/CCR7 in invasion of colorectal carcinoma cell line SW480]. Ai zheng = Aizheng = Chinese journal of cancer, 2009, Volume: 28, Issue:7 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chemokine CCL21; Colorectal Neoplasms; Etoposide; Humans; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Receptors, CCR7	2009
First-line cisplatin plus etoposide in high-grade metastatic neuroendocrine tumors of colon and rectum (MCRC NET): review of 8 cases. Anticancer research, 2011, Volume: 31, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cisplatin; Colorectal Neoplasms; Demography; Disease-Free Survival; Etoposide; Female; Humans; Male; Middle Aged; Neuroendocrine Tumors; Retrospective Studies; Tomography, X-Ray Computed; Treatment Outcome	2011
A novel topoisomerase inhibitor, daurinol, suppresses growth of HCT116 cells with low hematological toxicity compared to etoposide. Neoplasia (New York, N.Y.), 2011, Volume: 13, Issue:11 Topics: Animals; Antineoplastic Agents; Benzodioxoles; Carcinoma; Cell Proliferation; Colorectal Neoplasms; Drugs, Investigational; Etoposide; HCT116 Cells; Hematologic Diseases; Hep G2 Cells; Humans; Male; Mice; Mice, Nude; Models, Biological; Naphthalenes; Topoisomerase Inhibitors; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2011
Reliability of tumor primary cultures as a model for drug response prediction: expression profiles comparison of tissues versus primary cultures from colorectal cancer patients. Journal of cancer research and clinical oncology, 2012, Volume: 138, Issue:3 Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Cisplatin; Colorectal Neoplasms; Deoxycytidine; Down-Regulation; Doxorubicin; Etoposide; Floxuridine; Fluorescent Antibody Technique; Fluorouracil; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genomic Instability; Humans; Irinotecan; Metaphase; Paclitaxel; Polymerase Chain Reaction; Predictive Value of Tests; Protein Array Analysis; Reproducibility of Results; Tegafur; Tissue Array Analysis; Tumor Cells, Cultured; Up-Regulation; Uracil	2012
[Diagnosis, treatment and prognosis of neuroendocrine carcinoma of the colorectum]. Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2011, Volume: 14, Issue:12 Topics: Carcinoma, Neuroendocrine; Cisplatin; Colorectal Neoplasms; Etoposide; Female; Humans; Male; Neoplasm Staging; Prognosis; Retrospective Studies; Survival Rate	2011
Dual-mode interaction between quercetin and DNA-damaging drugs in cancer cells. Anticancer research, 2012, Volume: 32, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Camptothecin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclin B1; Cyclin-Dependent Kinase Inhibitor p21; DNA Damage; Drug Synergism; Etoposide; Flow Cytometry; Fluorouracil; Humans; Inhibitor of Apoptosis Proteins; Male; Prostatic Neoplasms; Quercetin; Survivin; Tumor Stem Cell Assay; Tumor Suppressor Protein p53	2012
Ribonuclease activity of p53 in cytoplasm in response to various stress signals. Cell cycle (Georgetown, Tex.), 2012, Apr-01, Volume: 11, Issue:7 Topics: Cell Line, Tumor; Colorectal Neoplasms; Cytoplasm; Doxorubicin; Eflornithine; ELAV Proteins; Ethylenes; Etoposide; Exonucleases; Gamma Rays; Humans; Ornithine Decarboxylase Inhibitors; Phosphorylation; Ribonucleases; RNA; RNA Stability; Stress, Physiological; Tumor Suppressor Protein p53	2012
Restoration of ASC expression sensitizes colorectal cancer cells to genotoxic stress-induced caspase-independent cell death. Cancer letters, 2013, May-01, Volume: 331, Issue:2 Topics: Apoptosis; Base Sequence; CARD Signaling Adaptor Proteins; Caspases; Cell Line, Tumor; Colorectal Neoplasms; Cytoskeletal Proteins; DNA Methylation; DNA Primers; Etoposide; Fluorescent Antibody Technique; HT29 Cells; Humans; Inflammasomes; MAP Kinase Signaling System; Mitochondria; Mutagens; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction	2013
Primary colorectal T-cell lymphoma. Journal of gastroenterology, 2003, Volume: 38, Issue:4 Topics: Antineoplastic Combined Chemotherapy Protocols; Barium Sulfate; Bleomycin; Colonoscopy; Colorectal Neoplasms; Cyclophosphamide; Cytarabine; Diagnosis, Differential; Doxorubicin; Enema; Etoposide; Humans; Lymphoma, T-Cell; Male; Methotrexate; Middle Aged; Prednisone; Vincristine	2003
The in vitro effects of CRE-decoy oligonucleotides in combination with conventional chemotherapy in colorectal cancer cell lines. European journal of biochemistry, 2004, Volume: 271, Issue:13 Topics: Base Sequence; Camptothecin; Cell Division; Cell Line, Tumor; Colorectal Neoplasms; Cyclin-Dependent Kinases; Etoposide; Flow Cytometry; Fluorouracil; Humans; In Vitro Techniques; Irinotecan; Oligonucleotides	2004
Retinoblastoma protein is required for efficient colorectal carcinoma cell apoptosis by histone deacetylase inhibitors in the absence of p21Waf. Biochemical pharmacology, 2005, Apr-01, Volume: 69, Issue:7 Topics: Adenocarcinoma; Apoptosis; Butyrates; Cell Cycle Proteins; Cell Line, Tumor; Colony-Forming Units Assay; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; DNA, Neoplasm; Doxorubicin; Enzyme Inhibitors; Etoposide; Flow Cytometry; Gene Deletion; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Kinetics; Retinoblastoma Protein; Transfection	2005
Etoposide sensitizes CT26 colorectal adenocarcinoma to radiation therapy in BALB/c mice. World journal of gastroenterology, 2005, Aug-21, Volume: 11, Issue:31 Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Colorectal Neoplasms; Combined Modality Therapy; Disease Models, Animal; Etoposide; Mice; Mice, Inbred BALB C; Radiotherapy	2005
Preclinical evaluation of a potent novel DNA-dependent protein kinase inhibitor NU7441. Cancer research, 2006, May-15, Volume: 66, Issue:10 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Cell Line, Tumor; CHO Cells; Chromones; Colorectal Neoplasms; Cricetinae; DNA Damage; DNA-Activated Protein Kinase; Drug Synergism; Etoposide; Female; Histones; Humans; Mice; Mice, Nude; Morpholines; Phosphorylation; Protein Kinase Inhibitors; Radiation-Sensitizing Agents; Tissue Distribution; Xenograft Model Antitumor Assays	2006
Ethylenediaminetetraacetic acid affects subcellular expression of clusterin protein in human colon adenocarcinoma COLO 205 cell line. Anti-cancer drugs, 2007, Volume: 18, Issue:1 Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Apoptosis; Calcium; Cell Line, Tumor; Cell Survival; Chelating Agents; Clusterin; Colorectal Neoplasms; Edetic Acid; Etoposide; Homeostasis; Humans; Molecular Biology; Protein Isoforms	2007
Chemotherapy and zoledronate sensitize solid tumour cells to Vgamma9Vdelta2 T cell cytotoxicity. Cancer immunology, immunotherapy : CII, 2007, Volume: 56, Issue:8 Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Burkitt Lymphoma; Carcinoma; Cell Line, Tumor; Cisplatin; Colorectal Neoplasms; Concanavalin A; Cytotoxicity, Immunologic; Diphosphonates; Doxorubicin; Drug Screening Assays, Antitumor; Drug Synergism; Etoposide; Female; Genes, T-Cell Receptor delta; Genes, T-Cell Receptor gamma; Humans; Imidazoles; Interferon-gamma; Lovastatin; Lung Neoplasms; Male; Membrane Glycoproteins; Neoplasms; Perforin; Pore Forming Cytotoxic Proteins; Prostatic Neoplasms; Receptors, Antigen, T-Cell, gamma-delta; T-Lymphocyte Subsets; Urinary Bladder Neoplasms; Vincristine; Zoledronic Acid	2007
c-MYC delays prometaphase by direct transactivation of MAD2 and BubR1: identification of mechanisms underlying c-MYC-induced DNA damage and chromosomal instability. Cell cycle (Georgetown, Tex.), 2007, Feb-01, Volume: 6, Issue:3 Topics: Anaphase; Apoptosis; Calcium-Binding Proteins; Cell Cycle Proteins; Cell Line, Tumor; Chromatin; Chromosomal Instability; Colorectal Neoplasms; DNA Damage; E-Box Elements; Etoposide; Genes, myc; Histones; Humans; Introns; Mad2 Proteins; Mitosis; Prometaphase; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-myc; Repressor Proteins; Transcriptional Activation	2007
Functional interaction of DNA topoisomerase IIalpha with the beta-catenin and T-cell factor-4 complex. Gastroenterology, 2007, Volume: 133, Issue:5 Topics: Adenoma; Antigens, Neoplasm; beta Catenin; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; DNA Topoisomerases, Type II; DNA-Binding Proteins; Enzyme Inhibitors; Etoposide; Gene Expression Regulation, Neoplastic; Humans; RNA, Small Interfering; Signal Transduction; TCF Transcription Factors; Thiobarbiturates; Topoisomerase II Inhibitors; Transcription Factor 7-Like 2 Protein; Wnt Proteins	2007
Expression of androgen receptor is negatively regulated by p53. Neoplasia (New York, N.Y.), 2007, Volume: 9, Issue:12 Topics: 5' Untranslated Regions; Adenocarcinoma; Androgens; Bone Neoplasms; Cell Line, Tumor; Colorectal Neoplasms; Consensus Sequence; DNA, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; Male; Neoplasms, Hormone-Dependent; Osteosarcoma; Promoter Regions, Genetic; Prostatic Neoplasms; Receptors, Androgen; RNA, Small Interfering; Transfection; Tumor Suppressor Protein p53	2007
Evaluation of the cytotoxic activity of gemcitabine in primary cultures of tumor cells from patients with hematologic or solid tumors. Seminars in oncology, 1995, Volume: 22, Issue:4 Suppl 11 Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Cisplatin; Cladribine; Colorectal Neoplasms; Cytarabine; Deoxycytidine; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Female; Gemcitabine; Humans; In Vitro Techniques; Leukemia; Lung Neoplasms; Lymphoma; Ribonucleotide Reductases; Tumor Cells, Cultured; Urogenital Neoplasms	1995
Biomodulation by hyperthermia of topoisomerase II-targeting drugs in human colorectal cancer cells. Japanese journal of cancer research : Gann, 1995, Volume: 86, Issue:11 Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Cycle; Colorectal Neoplasms; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Hot Temperature; Humans; Neoplasm Proteins; Teniposide; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Tumor Stem Cell Assay; Vincristine	1995
The effect of different chemotherapeutic agents on the enrichment of DNA mismatch repair-deficient tumour cells. British journal of cancer, 1998, Volume: 77, Issue:5 Topics: Adenocarcinoma; Antineoplastic Agents; Carboplatin; Cell Separation; Cisplatin; Colorectal Neoplasms; Cyclophosphamide; DNA Repair; DNA, Neoplasm; Doxorubicin; Enzyme Inhibitors; Etoposide; Humans; Melphalan; Paclitaxel; Tamoxifen; Thioguanine; Tumor Cells, Cultured; Tumor Stem Cell Assay	1998
A risk-benefit assessment of irinotecan in solid tumours. Drug safety, 1998, Volume: 18, Issue:6 Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Cisplatin; Colorectal Neoplasms; Diarrhea; Drug Therapy, Combination; Etoposide; Fluorouracil; Humans; Irinotecan; Lung Neoplasms; Neoplasms; Risk Assessment	1998
Resistance to cytotoxic drugs in DNA mismatch repair-deficient cells. Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:10 Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Antineoplastic Agents; Carboplatin; Carrier Proteins; Cisplatin; Colorectal Neoplasms; Cyclophosphamide; DNA Adducts; DNA Damage; DNA Repair; DNA-Binding Proteins; DNA, Neoplasm; Doxorubicin; Drug Resistance, Neoplasm; Endometrial Neoplasms; Etoposide; Female; Fluorouracil; Humans; Melphalan; Methylnitronitrosoguanidine; Mutagenesis; MutL Protein Homolog 1; MutS Homolog 2 Protein; Neoplasm Proteins; Nuclear Proteins; Paclitaxel; Proto-Oncogene Proteins; Thioguanine; Tumor Cells, Cultured	1997
Differential regulation of HSP27 oligomerization in tumor cells grown in vitro and in vivo. Oncogene, 2000, Oct-05, Volume: 19, Issue:42 Topics: Amino Acid Substitution; Animals; Antineoplastic Agents; Apoptosis; Aspartic Acid; Biopolymers; Caspase 3; Caspase 9; Caspases; Cell Communication; Cell Count; Cell-Free System; Cisplatin; Colorectal Neoplasms; Coumarins; Etoposide; Heat-Shock Proteins; Mice; Molecular Weight; Mutagenesis, Site-Directed; Neoplasm Proteins; Oligopeptides; Phosphorylation; Phosphoserine; Protein Processing, Post-Translational; Rats; Recombinant Fusion Proteins; Transfection; Tumor Cells, Cultured	2000
Quality of life in cancer patients treated by chemotherapy. Neoplasma, 2000, Volume: 47, Issue:6 Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cisplatin; Colorectal Neoplasms; Epirubicin; Etoposide; Female; Fluorouracil; Humans; Leucovorin; Lung Neoplasms; Male; Middle Aged; Neoplasms; Quality of Life; Stomach Neoplasms; Surveys and Questionnaires	2000
The role of the DNA mismatch repair system in the cytotoxicity of the topoisomerase inhibitors camptothecin and etoposide to human colorectal cancer cells. Cancer research, 2001, Sep-01, Volume: 61, Issue:17 Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents, Phytogenic; Base Pair Mismatch; Camptothecin; Carrier Proteins; Cell Cycle; Colorectal Neoplasms; DNA Repair; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Resistance, Multiple; Enzyme Inhibitors; Etoposide; Humans; MutL Protein Homolog 1; MutS Homolog 2 Protein; Neoplasm Proteins; Nuclear Proteins; Proto-Oncogene Proteins; Retrospective Studies; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53	2001
[Globalization of anti-cancer therapies]. Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:2 Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Camptothecin; Carboplatin; Cisplatin; Colorectal Neoplasms; Etoposide; Female; Humans; Irinotecan; Lung Neoplasms; Male; Neoplasms; Ovarian Neoplasms; Paclitaxel; Prostatic Neoplasms; Stomach Neoplasms	2002
Analysis of a conjugate between anti-carcinoembryonic antigen monoclonal antibody and alkaline phosphatase for specific activation of the prodrug etoposide phosphate. Cancer immunology, immunotherapy : CII, 1992, Volume: 34, Issue:5 Topics: Alkaline Phosphatase; Animals; Antibodies, Monoclonal; Biotransformation; Carcinoembryonic Antigen; Cell Line; Colorectal Neoplasms; Etoposide; Mice; Mice, Inbred DBA; Mice, Nude; Organophosphorus Compounds; Prodrugs; Tissue Distribution	1992
Cisplatin and etoposide in advanced colorectal carcinoma. Annals of oncology : official journal of the European Society for Medical Oncology, 1991, Volume: 2, Issue:9 Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colorectal Neoplasms; Drug Evaluation; Etoposide; Female; Humans; Male; Middle Aged; Remission Induction	1991
A phase I-II trial of continuous-infusion cisplatin, continuous-infusion 5-fluorouracil, and VP-16 in colorectal carcinoma. American journal of clinical oncology, 1990, Volume: 13, Issue:5 Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colorectal Neoplasms; Drug Evaluation; Etoposide; Female; Fluorouracil; Humans; Infusions, Intravenous; Leukopenia; Male; Middle Aged; Remission Induction; Thrombocytopenia	1990
A phase I/II trial of 5-fluorouracil and etoposide in metastatic colorectal carcinoma. American journal of clinical oncology, 1989, Volume: 12, Issue:6 Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Evaluation; Drug Synergism; Etoposide; Female; Fluorouracil; Humans; Male; Middle Aged	1989