Page last updated: 2024-08-23

etoposide and Colonic Neoplasms

etoposide has been researched along with Colonic Neoplasms in 126 studies

Research

Studies (126)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (7.94)	18.7374
1990's	42 (33.33)	18.2507
2000's	36 (28.57)	29.6817
2010's	36 (28.57)	24.3611
2020's	2 (1.59)	2.80

Authors

Authors	Studies
Chu, DT; Clement, JJ; Klein, LL; McDonald, EJ; Plattner, JJ; Yeung, CM	1
Clardy, J; Wagenaar, MM	1
Chaudhary, S; González-Sarrias, A; Harding, WW; Ponnala, S; Seeram, NP	1
Kim, SH; Lee, SH; Lee, SK; Oh, DC; Oh, KB; Shin, J; Shin, Y	1
Bae, SY; Hong, JY; Jung, C; Kang, SS; Lee, SK; Park, HJ	1
Fischer, C; Hetterling, G; Kliem, M; Micikas, RJ; Plauth, A; Rousseau, M; Sauer, S; Schroeder, FC; Siems, K; Weidner, C; Wowro, SJ	1
Islam, MS; Kadi, AA; Kwon, Y; Park, S; Rahman, AF; Song, C	1
Hosono, M; Namikoshi, M; Rotinsulu, H; Sumilat, DA; Tatsuta, T; Wewengkang, DS; Yamazaki, H	1
Alía Navarro, V; Barrill Corpa, AM; De Frutos González, B; Ferreiro Monteagudo, R; Ferrer Gómez, A; Martínez Delfrade, Í; Morón García, B; Peñas García, B; Perna Monroy, C; Sotoca Rubio, P	1
Esperandim, TR; Fernandes, G; Furtado, RA; Nicolella, HD; Ozelin, SD; Ribeiro, AB; Rinaldi-Neto, F; Senedese, JM; Tavares, DC; Veneziani, RCS	1
Fukuda, M; Hosokawa, M; Iwakawa, S; Masuda, A; Tanaka, S; Ueda, K	1
Chen, W; Clement, S; Deng, W; Engel, A; Goldys, EM; Guller, A; Zhao, Z	1
Choi, KC; Han, EJ; Jeong, MH; Kwak, S; Lee, SH; Park, SH; Park, SY; Seo, J; Sung, GJ; Yoo, JY; Yoon, HG	1
Park, HR; Yoon, SB	1
Chi, SG; Kim, HJ; Lee, CK; Moon, JR; Oh, SJ	1
Boutzios, G; Chatzellis, E; Kaltsas, G; Koumarianou, A; Tsavaris, N	1
Bharatam, PV; Choudhuri, M; Das, D; Guchhait, SK; Jain, V; Kandekar, S; Kashyap, M; Kundu, CN; Mohapatra, P; Preet, R; Renu Prasad, MU; Satapathy, SR; Siddharth, S	1
Amiri, F; Jeddi-Tehrani, M; Koohdani, F; Vafa, M; Zand, H; Zarnani, AH	1
Han, Y; Ma, DH; Wang, ZH; Xing, Y	1
Jain, CK; Majumder, HK; Roychoudhury, S	1
Chen, Y; Ding, J; Huan, XJ; Miao, ZH; Song, SS; Sun, YM; Tian, QT; Wang, W; Wang, YQ; Yang, CH; Yi, JM; Zhang, XF	1
Abdullah, A; Branick, KA; Freeling, JL; Rezvani, K; Sane, S; Wang, H; Zhang, D	1
Hassan, U; Mozayani, B; Wong, NA	1
Agama, K; Brünner, N; Doroshow, JH; Jensen, NF; Knudsen, BR; Pfister, TD; Pommier, Y; Roy, A; Rømer, MU; Smith, DH; Stenvang, J; Zhang, HL	1
Armbruester, V; Heyne, K; Mestres, P; Mueller, D; Roemer, K; Schmitt, K	1
Cho, BJ; Hong, SW; Hwang, YI; Jin, DH; Jung, DJ; Kang, JS; Kim, D; Kim, JE; Lee, WJ; Shin, JS	1
Ju, S; Ni, H; Wang, H; Wang, X; Xu, J; Zhu, J	1
Hayashi, H; Kakimoto, T; Kurai, H; Mihara, A; Nakazato, T; Sanada, Y; Suzuki, K; Tachikawa, N; Yoshida, S; Yoshimura, Y	1
Bi, F; Lang, N; Liu, M; Liu, Z; Qiu, M; Tang, QL	1
Fabian, I; Halperin, D; Priel, E; Reuveni, D; Shalit, I	1
Baguley, BC; Chen, YY; Finlay, GJ; Kirker, JA; Marshall, ES; Richardson, E	1
Asanuma, H; Hasegawa, T; Hirata, K; Hirohashi, Y; Inoda, S; Ishitani, K; Kondo, T; Morita, R; Nakatsugawa, M; Nishizawa, S; Sato, N; Takahashi, A; Tamura, Y; Terui, T; Torigoe, T; Tsuruma, T	1
Akiyama, S; Gamoh, M; Narasaka, T; Niitani, T; Ohto, T	1
Bollag, WB; Liu, F; Liu, K; Liu, Q; Robertson, K; Wu, P; Yang, D	1
Delalande, F; Domon-Dell, C; Duluc, I; Freund, JN; Gross, I; Martin, E; Renouf, B; Saandi, T; Soret, C; Vanier, M	1
Aragon-Ching, JB; El-Ayass, W; Karcher, DS; Yu, EM	1
Balzer, E; Grabias, B; Kontrogianni-Konstantopoulos, A; Mameza, MG; Perry, NA; Shriver, M	1
Choe, W; Chung, SH; Ha, J; Kang, I; Kim, HS; Kim, SS; Lee, S; Lim, JS; Wannatung, T; Yang, WK	1
Hollingsworth, J; Koh, GY; Liu, Z; Russo, PS; Stout, RW; Zhang, F	1
Hasegawa, K; Hidaka, K; Hieda, N; Hiramoto, S; Honjo, H; Kakiuchi, N; Kawanami, C; Kondo, M; Kuriyama, K; Matsunaga, Y; Miyake, N; Mizota, A; Mizuguchi, A; Nishida, Y; Nishikawa, K; Shirase, T; Sogabe, Y; Tanabe, W; Yasumura, S; Yoshioka, A; Zaima, C	1
Callegari-Jacques, SM; da Silva, VD; Filippi-Chiela, EC; Jurkovski, B; Lenz, G; Oliveira, MM	1
Bozko, P; Larsen, AK; Raymond, E; Skladanowski, A	1
Krüger, I; Lindenfelser, R; Scherwitz, P	1
Bolton, M; Copur, S; Frankforter, S; Fruehling, RM; Ledakis, P; Mleczko, KL; Muhvic, J; Norvell, M; Novinski, D; VanWie, E	1
Kamata, J; Kitoh, K; Kotake, Y; Koyanagi, N; Nagasu, T; Nakamura, K; Niijima, J; Okada, T; Sugumi, H; Uenaka, T; Yamaguchi, A; Yoshimatsu, K; Yoshino, H	1
Funahashi, Y; Nakamura, K; Taniguchi, T; Yoshimatsu, K	1
Kamata, J; Kitoh, K; Kotake, Y; Koyanagi, N; Nagasu, T; Nakamura, K; Niijima, J; Okada, T; Sugumi, H; Taniguchi, T; Uenaka, T; Yamaguchi, A; Yoshimatsu, K; Yoshino, H	1
Bernardi, R; Brison, O; Counis, MF; Denegri, M; Donzelli, M; Gorrini, C; Negri, C; Ranzani, GN; Scovassi, AI; Supino, R; Torriglia, A	1
El-Deiry, WS; Wang, S	1
Casares, N; Droin, N; Fromentin, A; Garrido, C; Ghiringhelli, F; Gurbuxani, S; Hamai, A; Hammann, A; Kroemer, G; Moutet, M; Parcellier, A; Pequignot, M; Schmitt, E; Solary, E	1
Belcourt, MF; Cory, JG; Lin, ZP; Sartorelli, AC	1
Jothy, S; Lakshman, M; Rubenthiran, U; Subramaniam, V	1
Beaudoin, A; De Gramont, A; El Mesbahi, O; Louvet, C	1
Kobayashi, S	1
Alberts, SR; Erlichman, C; Furth, A; Lathia, CD; Molina, JR; Reid, JM; Safgren, SL; Sloan, JA	1
Blandino, G; Bossi, G; Lapi, E; Rinaldo, C; Sacchi, A; Strano, S	1
Chimenti, D; Iorio, M; Maurich, T; Turchi, G	1
Kroemer, G; Larochette, N; Massard, C; Métivier, D; Pauleau, AL; Sabatier, L; Soria, JC; Zermati, Y	1
Apetoh, L; Casares, N; Castedo, M; Ciccosanti, F; Fimia, GM; Ghiringhelli, F; Kroemer, G; Larochette, N; Métivier, D; Mignot, G; Obeid, M; Panaretakis, T; Perfettini, JL; Piacentini, M; Tesniere, A; van Endert, P; Zitvogel, L	1
Clarke, C; Smyth, MJ	1
Cha, MR; Cho, SM; Choo, SJ; Hwang, JH; Hwang, YI; Kim, JY; Park, HR; Ryoo, IJ; Shin-Ya, K; Tomida, A; Tsukumo, Y; Yoo, ID	1
Castro, MA; Gelain, DP; Grivicich, I; Klamt, F; Moreira, JC; Passos, DT	1
Alberts, DS; Dorr, RT	1
Fujimura, T; Fujita, H; Fushida, S; Hirono, Y; Itoh, H; Kaji, M; Kinami, S; Nakagawara, H; Nakai, M; Yonemura, Y	1
Iigo, M; Sagawa, K; Shimamura, M; Tsuda, H	1
Iigo, M; Moriyama, M; Tsuda, H	1
Elliott, WL; Howard, CT; Leopold, WR; Roberts, BJ	1
Casazza, AM; Long, BH	1
Lorico, A; Rappa, G; Sartorelli, AC	1
Inaba, M; Kawada, S; Mitsuhashi, J; Nakano, H	1
Donahue, JP; Dulmadge, EA; Vasanthakumar, G; Wilkoff, LJ	1
Arakawa, H; Iguchi, T; Kurama, M; Mano, E; Nakagawa, S; Okura, A; Tanaka, N; Yoshinari, T	1
Basson, MD; Rashid, Z	1
Aoyagi, K; Kobunai, T; Oh-hara, T; Shibata, J; Sugimoto, Y; Terada, T; Tsuruo, T; Utsugi, T; Wierzba, K; Yamada, Y	1
Anderson, NR; Lokich, JJ; Moore, CL	1
Fujimura, T; Fushida, S; Hirono, Y; Kawamura, T; Kinami, S; Minami, M; Miwa, K; Miyazaki, I; Nishimura, G; Noguchi, M; Nojima, N; Sato, T; Shiobara, S; Yonemura, Y	1
Crilly, R; Fromm, D; Kessel, D; Luo, Y; Webber, J	1
Arita, D; Ishioka, C; Kambe, M; Kanamaru, R	1
Cowan, KH; Fukuda, M; Ikeda, K; Kohno, S; Matsuo, I; Nakano, R; Narasaki, F; Oka, M; Soda, H; Takatani, H; Terashi, K; Tomonaga, M	1
El-Deiry, WS; Somasundaram, K	1
Berger, NA; Gordon, NH; Mackay, W; Whitacre, CM; Zborowska, E	1
Aebi, S; de las Alas, MM; Fink, D; Howell, SB; Los, G	1
Aoyagi, K; Aoyagi, Y; Asao, T; Okazaki, S; Sano, M; Utsugi, T; Wierzba, K; Yamada, Y	1
El-Deiry, WS; Peters, C; Saftig, P; Wu, GS	1
Bréard, J; Dimanche-Boitrel, MT; Droin, N; Dubrez, L; Eymin, B; Renvoizé, C; Solary, E	1
Cheshire, PJ; Hallman, JD; Houghton, JA; Houghton, PJ; Li, Y; Luo, X; Lutz, L	1
Ciesielski, MJ; Fenstermaker, RA	1
Akutsu, M; Kano, Y; Mori, K; Suzuki, K; Tsunoda, S; Yazawa, Y	1
Asano, M; Higashi, S; Hosono, Y; Kane, T; Kato, C; Matsumoto, K; Sakoda, M; Sakumoto, H; Sumiyoshi, K; Takahahsi, T; Takahashi, M; Yamamoto, A	1
Bigg, DC; Bronckart, Y; Chaboteaux, C; da Costa, PM; Decaestecker, C; Gordover, L; Harper, L; Kiss, R; Lavergne, O; Lesueur-Ginot, L; Malonne, H; Philippart, P	1
Kojima, T; Naruse, T; Tokunaga, Y	1
Filipeanu, CM; Klappe, K; Kok, JW; Koning, H; Müller, M; Veldman, RJ	1
Banáth, JP; Johnston, PJ; MacPhail, SH; Olive, PL; Oloumi, A	1
Kobayashi, A; Yamaguchi, M	1
Aikou, T; Akiyama, S; Furukawa, T; Ikeda, R; Kitazono, M; Nagayama, S; Okumura, H; Seto, K; Sumizawa, T	1
Baguley, BC; Baker, M; Bootle, D; Charlton, PA; Dangerfield, W; Denny, WA; Kofler, B; Mistry, P; Okiji, S; Stewart, AJ	1
Goehle, S; Lamb, JR; Ludlow, C; Simon, JA	1
Mahyar-Roemer, M; Roemer, K	1
Andreassen, PR; Lacroix, FB; Lohez, OD; Margolis, RL	1
Funato, T; Kaku, M; Kozawa, K; Sasaki, T	1
Bernis, C; de La Cámara, R; Osorio, S	1
Ashkenazi, A; Fong, S; Lawrence, D; LeBlanc, H; Morlan, J; Schow, P; Schwall, R; Sinicropi, D; Totpal, K; Varfolomeev, E	1
Brill, S; Halpern, Z; Khaikin, M; Kouniavsky, G; Papa, M; Zippel, D; Zvibel, I	1
Hartmann, D; Obrecht, JP; Stalder, GA	1
Carbone, PP; Douglass, HO; Evans, JT; Lavin, PT; Mittelman, A	1
Hahn, RG; Moertel, CG; Perry, MC; Reitemeier, RJ; Schutt, AJ	1
Bertrand, R; Kerrigan, D; O'Connor, PM; Pommier, Y	1
Banáth, JP; Olive, PL	1
Hasegawa, E; Hirakawa, S; Momose, K; Ohmura, G; Watanabe, H	1
Altermatt, HJ; Donatsch, P; Hiestand, PC; Keller, RP; Laissue, JA; Zihlmann, H	1
de Vries, EG; Meijer, C; Mulder, NH; Mulder, PO; Nanninga, AG; Uges, DR; van der Graaf, WT; Vellenga, E	1
Baguley, BC; Finlay, GJ	1
Brattain, MG; Casazza, AM; Long, BH; Lorico, A; Wang, L; Wang, RC	1
Bertrand, R; Jenkin, J; Kerrigan, D; Pommier, Y; Sarang, M	1
Ekimoto, H; Ishii, T; Kusama, K; Okamoto, K; Takahashi, K	1
Harstrick, A; Köhne-Wömpner, CH; Poliwoda, H; Schmoll, HJ; Schöber, C; Wilke, H	1
Izumi, R; Kobayashi, K; Matsui, O; Miyazaki, I; Shimizu, K; Watanabe, T	1
Creger, RJ; Fox, RM; Lazarus, HM	1
Senter, PD	1
Basler, GA; Casazza, AM; Crosswell, AR; Rose, WC; Saulnier, M; Trail, PA	1
Imamura, Y; Matsusita, K; Okutani, T; Ono, S; Oya, M; Tokisue, M; Yasutake, K; Yoshimura, Y	1
Kashani-Sabet, M; Scanlon, KJ; Sowers, LC	1
Peters, W; Souhami, R	1
Brown, JP; Hellström, I; Hellström, KE; Hirschberg, DL; Saulnier, MG; Schreiber, GJ; Senter, PD	1
Atkins, JN; Capizzi, RL; Caponera, ME; Craig, JB; Jackson, DV; Muss, HB; Powell, BL; Richards, F; White, DR; Zekan, PJ	1
Nishikawa, K; Okamoto, K; Seki, T; Shibasaki, C; Takahashi, K; Uchida, T	1

Reviews

4 review(s) available for etoposide and Colonic Neoplasms

Article	Year
Current concepts in the diagnosis and management of poorly differentiated gastrointestinal neuroendocrine carcinomas. Endokrynologia Polska, 2013, Volume: 64, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Large Cell; Carcinoma, Neuroendocrine; Colonic Neoplasms; Diagnosis, Differential; Diagnostic Imaging; Etoposide; Gastrointestinal Neoplasms; Humans; Lung Neoplasms; Platinum Compounds; Prognosis; Receptors, Somatostatin; Retrospective Studies; Small Cell Lung Carcinoma	2013
Complete response to EPOCH in a patient with HIV and extracavitary primary effusion lymphoma involving the colon: a case report and review of literature. Clinical lymphoma, myeloma & leukemia, 2012, Volume: 12, Issue:2 Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Cyclophosphamide; Doxorubicin; Etoposide; HIV Infections; Humans; Lymphoma, Primary Effusion; Male; Middle Aged; Positron-Emission Tomography; Prednisone; Treatment Outcome; Vincristine	2012
Modulation of cytotoxic drug activity by dipyridamole. Cancer treatment reviews, 1990, Volume: 17 Suppl A Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Cytarabine; Dipyridamole; Drug Interactions; Etoposide; Fluorouracil; Humans; Leucovorin; Methotrexate	1990
High dose chemotherapy in solid tumours in adults. Clinics in haematology, 1986, Volume: 15, Issue:1 Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Breast Neoplasms; Carcinoma, Small Cell; Carmustine; Cell Separation; Cisplatin; Colonic Neoplasms; Cyclophosphamide; Etoposide; Glioma; Humans; Lung Neoplasms; Male; Melanoma; Melphalan; Neoplasms; Testicular Neoplasms; Whole-Body Irradiation	1986

Trials

4 trial(s) available for etoposide and Colonic Neoplasms

Article	Year
A phase I and pharmacokinetic study of the selective, non-peptidic inhibitor of matrix metalloproteinase BAY 12-9566 in combination with etoposide and carboplatin. Anti-cancer drugs, 2005, Volume: 16, Issue:9 Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Biphenyl Compounds; Carboplatin; Cohort Studies; Colonic Neoplasms; Enzyme Inhibitors; Etoposide; Female; Humans; Male; Matrix Metalloproteinase Inhibitors; Melanoma; Middle Aged; Neoplasms; Neoplasms, Unknown Primary; Neutropenia; Organic Chemicals; Phenylbutyrates; Thrombocytopenia; Thymoma; Treatment Outcome; Vomiting	2005
[Arterial infusion therapy with implantable port for inoperable hepatobiliary tumors]. Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:12 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neoplasms; Cisplatin; Colonic Neoplasms; Drug Administration Schedule; Epirubicin; Etoposide; Female; Fluorouracil; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Mitomycin; Prognosis; Stomach Neoplasms	1999
Phase II evaluation of diglycoaldehyde, VP-16-213, and the combination of methyl-CCNU and beta-2'-deoxythioguanosine in previously treated patients with colorectal cancer: an Eastern Cooperative Oncology Group study (EST-1275). Cancer treatment reports, 1979, Volume: 63, Issue:8 Topics: Aldehydes; Colonic Neoplasms; Deoxyguanosine; Drug Evaluation; Drug Therapy, Combination; Etoposide; Female; Humans; Inosine; Male; Nitrosourea Compounds; Podophyllotoxin; Rectal Neoplasms; Semustine; Thionucleosides	1979
Phase II studies of dianhydrogalactitol and VP-16-213 in colorectal cancer. Cancer treatment reports, 1976, Volume: 60, Issue:9 Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Clinical Trials as Topic; Colonic Neoplasms; Drug Evaluation; Ethers, Cyclic; Etoposide; Female; Galactitol; Humans; Male; Middle Aged; Podophyllotoxin; Rectal Neoplasms; Sugar Alcohols	1976

Other Studies

118 other study(ies) available for etoposide and Colonic Neoplasms

Article	Year
Synthesis and antitumor activity of structural analogues of the epipodophyllotoxins. Journal of medicinal chemistry, 1991, Volume: 34, Issue:3 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma; Chemical Phenomena; Chemistry; Colonic Neoplasms; Etoposide; Humans; Indans; Leukemia P388; Lung Neoplasms; Mice; Molecular Structure; Podophyllotoxin; Structure-Activity Relationship; Tumor Cells, Cultured	1991
Dicerandrols, new antibiotic and cytotoxic dimers produced by the fungus Phomopsis longicolla isolated from an endangered mint. Journal of natural products, 2001, Volume: 64, Issue:8 Topics: Antibiotics, Antineoplastic; Ascomycota; Bacillus subtilis; Colonic Neoplasms; Florida; Geotrichum; Humans; Lamiaceae; Lung Neoplasms; Magnetic Resonance Spectroscopy; Molecular Structure; Saccharomyces cerevisiae; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Staphylococcus aureus; Stereoisomerism; Tumor Cells, Cultured; Xanthenes; Xanthones	2001
Cytotoxicity of aporphines in human colon cancer cell lines HCT-116 and Caco-2: an SAR study. Bioorganic & medicinal chemistry letters, 2011, Aug-01, Volume: 21, Issue:15 Topics: Aporphines; Caco-2 Cells; Colonic Neoplasms; Drug Screening Assays, Antitumor; HCT116 Cells; Humans; Structure-Activity Relationship	2011
Salternamides A-D from a Halophilic Streptomyces sp. Actinobacterium. Journal of natural products, 2015, Apr-24, Volume: 78, Issue:4 Topics: Actinobacteria; Antineoplastic Agents; Circular Dichroism; Colonic Neoplasms; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Molecular Structure; Polyenes; Polyunsaturated Alkamides; Republic of Korea; Salt-Tolerant Plants; Sodium-Potassium-Exchanging ATPase; Streptomyces	2015
Antitumor Activity of Americanin A Isolated from the Seeds of Phytolacca americana by Regulating the ATM/ATR Signaling Pathway and the Skp2-p27 Axis in Human Colon Cancer Cells. Journal of natural products, 2015, Dec-24, Volume: 78, Issue:12 Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; CDC2 Protein Kinase; Checkpoint Kinase 1; Checkpoint Kinase 2; Colonic Neoplasms; Dioxins; G2 Phase Cell Cycle Checkpoints; HCT116 Cells; Humans; Mice; Mice, Nude; Molecular Structure; Phytolacca americana; Protein Kinases; Seeds; Signal Transduction; Tumor Suppressor Protein p53	2015
Amorfrutin C Induces Apoptosis and Inhibits Proliferation in Colon Cancer Cells through Targeting Mitochondria. Journal of natural products, 2016, Jan-22, Volume: 79, Issue:1 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Caspases; Cell Cycle Checkpoints; Cell Proliferation; Colonic Neoplasms; Drug Screening Assays, Antitumor; Female; G1 Phase Cell Cycle Checkpoints; Glycyrrhiza; HT29 Cells; Humans; Inhibitory Concentration 50; Male; Membrane Potential, Mitochondrial; Mitochondria; Molecular Structure; Morocco; Peroxisome Proliferator-Activated Receptors; Plant Roots; Reactive Oxygen Species; Salicylates; Structure-Activity Relationship	2016
Fluorescein hydrazones: A series of novel non-intercalative topoisomerase IIα catalytic inhibitors induce G1 arrest and apoptosis in breast and colon cancer cells. European journal of medicinal chemistry, 2017, Jan-05, Volume: 125 Topics: Animals; Antigens, Neoplasm; Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA-Binding Proteins; Dose-Response Relationship, Drug; Female; Fluorescein; G1 Phase Cell Cycle Checkpoints; Humans; Hydrazones; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors	2017
Lissoclibadin 1, a Polysulfur Aromatic Alkaloid from the Indonesian Ascidian Lissoclinum cf. badium, Induces Caspase-Dependent Apoptosis in Human Colon Cancer Cells and Suppresses Tumor Growth in Nude Mice. Journal of natural products, 2017, 02-24, Volume: 80, Issue:2 Topics: Adenocarcinoma; Alkaloids; Animals; Antineoplastic Agents; Apoptosis; Caspases; Cell Proliferation; Colonic Neoplasms; Female; HeLa Cells; Humans; Indonesia; MCF-7 Cells; Mice; Mice, Nude; Molecular Structure; Urochordata	2017
Localized Colonic Small-Cell Carcinoma with Pathological Complete Response after Neoadjuvant Cisplatin and Etoposide: A Case Report. Current oncology (Toronto, Ont.), 2023, 09-14, Volume: 30, Issue:9 Topics: Aged; Carcinoma, Small Cell; Cisplatin; Colonic Neoplasms; Etoposide; Humans; Male; Neoadjuvant Therapy; Neoplasm Recurrence, Local	2023
Manool, a diterpene from Salvia officinalis, exerts preventive effects on chromosomal damage and preneoplastic lesions. Mutagenesis, 2021, 05-31, Volume: 36, Issue:2 Topics: Animals; Anticarcinogenic Agents; Cell Line; Colonic Neoplasms; Cricetinae; Disease Models, Animal; Diterpenes; DNA Damage; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Hydrogen Peroxide; Male; Mice; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagenicity Tests; NF-kappa B; Nitric Oxide; Plant Extracts; Precancerous Conditions; Rats; Rats, Wistar; Salvia officinalis	2021
Monophosphorylation by deoxycytidine kinase affects apparent cellular uptake of decitabine in HCT116 colon cancer cells. Drug metabolism and pharmacokinetics, 2017, Volume: 32, Issue:6 Topics: Antimetabolites, Antineoplastic; Azacitidine; Camptothecin; Colonic Neoplasms; Cytarabine; Decitabine; Deoxycytidine; Deoxycytidine Kinase; Equilibrative Nucleoside Transporter 1; Etoposide; Gemcitabine; HCT116 Cells; Humans; Irinotecan; Phosphorylation	2017
Controlled gene and drug release from a liposomal delivery platform triggered by X-ray radiation. Nature communications, 2018, 07-13, Volume: 9, Issue:1 Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Combined Modality Therapy; Delayed-Action Preparations; Doxorubicin; Drug Liberation; Etoposide; Fluoresceins; Folic Acid; Gene Silencing; Gold; HCT116 Cells; Humans; Liposomes; Metal Nanoparticles; Mice; Oligoribonucleotides, Antisense; PC12 Cells; Photochemotherapy; Photosensitizing Agents; Rats; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I; Singlet Oxygen; Verteporfin; X-Rays; Xenograft Model Antitumor Assays	2018
Serine/threonine kinase 31 promotes PDCD5-mediated apoptosis in p53-dependent human colon cancer cells. Journal of cellular physiology, 2019, Volume: 234, Issue:3 Topics: Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; DNA Damage; Etoposide; Humans; Neoplasm Proteins; Protein Serine-Threonine Kinases; Tumor Suppressor Protein p53	2019
Arctigenin Inhibits Etoposide Resistance in HT-29 Colon Cancer Cells during Microenvironmental Stress. Journal of microbiology and biotechnology, 2019, Apr-28, Volume: 29, Issue:4 Topics: Antineoplastic Agents; Apoptosis; Cell Survival; Colonic Neoplasms; Colony-Forming Units Assay; DNA Topoisomerases, Type II; Drug Resistance, Neoplasm; Endoplasmic Reticulum Chaperone BiP; Etoposide; Furans; Heat-Shock Proteins; HT29 Cells; Humans; Lignans; Stress, Physiological; Tumor Microenvironment	2019
TGF-β1 protects colon tumor cells from apoptosis through XAF1 suppression. International journal of oncology, 2019, Volume: 54, Issue:6 Topics: Adaptor Proteins, Signal Transducing; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Disease Progression; Down-Regulation; Drug Resistance, Neoplasm; Etoposide; Fluorouracil; Gamma Rays; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Neoplasm Proteins; Promoter Regions, Genetic; ras Proteins; Transforming Growth Factor beta1	2019
Structural elaboration of a natural product: identification of 3,3'-diindolylmethane aminophosphonate and urea derivatives as potent anticancer agents. ChemMedChem, 2013, Volume: 8, Issue:11 Topics: Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Etoposide; Humans; Immunohistochemistry; Indoles; Kidney Neoplasms; Molecular Structure; Organophosphorus Compounds	2013
Synergistic anti-proliferative effect of resveratrol and etoposide on human hepatocellular and colon cancer cell lines. European journal of pharmacology, 2013, Oct-15, Volume: 718, Issue:1-3 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Drug Synergism; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Resveratrol; Stilbenes; Tumor Suppressor Protein p53	2013
FTY720 enhances chemosensitivity of colon cancer cells to doxorubicin and etoposide via the modulation of P-glycoprotein and multidrug resistance protein 1. Journal of digestive diseases, 2014, Volume: 15, Issue:5 Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Survival; Chemotherapy, Adjuvant; Colonic Neoplasms; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Fingolimod Hydrochloride; Gene Expression; Humans; Immunosuppressive Agents; Propylene Glycols; Sphingosine	2014
Selective killing of G2 decatenation checkpoint defective colon cancer cells by catalytic topoisomerase II inhibitor. Biochimica et biophysica acta, 2015, Volume: 1853, Issue:5 Topics: Biocatalysis; Cell Cycle Checkpoints; Cell Death; Cell Line, Tumor; Cell Survival; Chromosomes, Human; Colonic Neoplasms; Diketopiperazines; Etoposide; G2 Phase; HEK293 Cells; Humans; Mitosis; Mitotic Index; Piperazines; Topoisomerase II Inhibitors; Tumor Stem Cell Assay	2015
Dual targeting of microtubule and topoisomerase II by α-carboline derivative YCH337 for tumor proliferation and growth inhibition. Oncotarget, 2015, Apr-20, Volume: 6, Issue:11 Topics: Animals; Apoptosis; Binding Sites; Binding, Competitive; Carbolines; Cell Line, Tumor; Colchicine; Colonic Neoplasms; DNA Breaks, Double-Stranded; DNA Topoisomerases, Type II; DNA, Neoplasm; DNA, Superhelical; Drug Interactions; Drug Screening Assays, Antitumor; Etoposide; Humans; Inhibitory Concentration 50; Metaphase; Mice; Mice, Nude; Microtubules; Molecular Structure; Neoplasm Proteins; Paclitaxel; Topoisomerase II Inhibitors; Tubulin; Tubulin Modulators; Vincristine	2015
A plant alkaloid, veratridine, potentiates cancer chemosensitivity by UBXN2A-dependent inhibition of an oncoprotein, mortalin-2. Oncotarget, 2015, Sep-15, Volume: 6, Issue:27 Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Cytoplasm; Disease Progression; Enhancer Elements, Genetic; Etoposide; Female; Fluorouracil; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Green Fluorescent Proteins; HCT116 Cells; HSP70 Heat-Shock Proteins; Humans; Hyaluronan Receptors; Mice; Mice, Nude; Mitochondrial Proteins; Neoplasm Transplantation; Plant Extracts; Protein Array Analysis; Tumor Suppressor Protein p53; Ubiquitin; Ubiquitins; Veratridine	2015
Primary combined neuroendocrine carcinoma (small-cell type) and squamous cell carcinoma of the colon. Histopathology, 2016, Volume: 68, Issue:5 Topics: Aged; Antineoplastic Agents, Phytogenic; Carcinoma, Neuroendocrine; Carcinoma, Squamous Cell; Colon; Colonic Neoplasms; Etoposide; Fatal Outcome; Humans; Male; Platinum; Point Mutation; Proto-Oncogene Proteins p21(ras); Tomography, X-Ray Computed	2016
Characterization of DNA topoisomerase I in three SN-38 resistant human colon cancer cell lines reveals a new pair of resistance-associated mutations. Journal of experimental & clinical cancer research : CR, 2016, Mar-31, Volume: 35 Topics: Benzodioxoles; Binding Sites; Camptothecin; Cell Line, Tumor; Chromosome Deletion; Colonic Neoplasms; DNA Topoisomerases, Type I; Drug Resistance, Neoplasm; Epirubicin; Etoposide; Gene Dosage; Guanidines; HCT116 Cells; HT29 Cells; Humans; Hydrazones; Irinotecan; Isoquinolines; Mutation	2016
Resistance of mitochondrial p53 to dominant inhibition. Molecular cancer, 2008, Jun-12, Volume: 7 Topics: Alpha-Amanitin; Antineoplastic Agents; Apoptosis; Cell Proliferation; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; DNA-Binding Proteins; Etoposide; Fluorouracil; Gene Expression Regulation, Neoplastic; Genes, Dominant; HCT116 Cells; Humans; Mitochondria; Mutation; Nuclear Proteins; Promoter Regions, Genetic; Protein Binding; Time Factors; Transcriptional Activation; Tumor Protein p73; Tumor Suppressor Protein p53; Tumor Suppressor Proteins	2008
Foxp3 expression in p53-dependent DNA damage responses. The Journal of biological chemistry, 2010, Mar-12, Volume: 285, Issue:11 Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Death; Cell Division; Colonic Neoplasms; DNA Damage; Doxorubicin; Etoposide; Female; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Imidazoles; Phosphorylation; Piperazines; Proto-Oncogene Proteins c-mdm2; Tumor Suppressor Protein p53	2010
Livin gene plays a role in drug resistance of colon cancer cells. Clinical biochemistry, 2010, Volume: 43, Issue:7-8 Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Line, Tumor; Colonic Neoplasms; Drug Resistance, Neoplasm; Etoposide; Fluorouracil; Humans; Inhibitor of Apoptosis Proteins; Neoplasm Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Vincristine	2010
[Successful treatment with hyper-CVAD and highly active anti-retroviral therapy (HAART) for AIDS-related Burkitt lymphoma]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 2010, Volume: 51, Issue:3 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Antiretroviral Therapy, Highly Active; Burkitt Lymphoma; Colonic Neoplasms; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Etoposide; Humans; Lymphoma, AIDS-Related; Male; Methotrexate; Prednisone; Treatment Outcome; Vincristine	2010
Establishment and biological characteristics of oxaliplatin-resistant human colon cancer cell lines. Chinese journal of cancer, 2010, Volume: 29, Issue:7 Topics: AC133 Antigen; Antibiotics, Antineoplastic; Antigens, CD; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Cycle; Cell Line, Tumor; Cisplatin; Colonic Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Epirubicin; Etoposide; Fluorouracil; Glycoproteins; Humans; Hyaluronan Receptors; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organoplatinum Compounds; Oxaliplatin; Peptides; Vincristine	2010
Moxifloxacin enhances etoposide-induced cytotoxic, apoptotic and anti-topoisomerase II effects in a human colon carcinoma cell line. International journal of oncology, 2010, Volume: 37, Issue:2 Topics: Antineoplastic Agents; Apoptosis; Aza Compounds; Carcinoma; Cell Cycle; Cell Line, Tumor; Colonic Neoplasms; Cytotoxins; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Enzyme Inhibitors; Etoposide; Fluoroquinolones; HT29 Cells; Humans; Moxifloxacin; Quinolines; Topoisomerase II Inhibitors	2010
In vivo and in vitro assessment of the action of SN 28049, a benzonaphthyridine derivative targeting topoisomerase II, on the murine Colon 38 carcinoma. Investigational new drugs, 2011, Volume: 29, Issue:6 Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Colonic Neoplasms; DNA Damage; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Etoposide; Female; Flow Cytometry; In Situ Nick-End Labeling; In Vitro Techniques; Mice; Mice, Inbred C57BL; Naphthyridines; Phosphorylation	2011
Cytotoxic T lymphocytes efficiently recognize human colon cancer stem-like cells. The American journal of pathology, 2011, Volume: 178, Issue:4 Topics: Animals; Antigens; Antineoplastic Agents; Benzimidazoles; Camptothecin; Cell Line, Tumor; Colonic Neoplasms; Etoposide; Humans; Irinotecan; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Transplantation; Neoplastic Stem Cells; Peptides; T-Lymphocytes, Cytotoxic	2011
[Poorly-differentiated neuroendocrine carcinoma of ascending colon with liver metastases successfully treated with carboplatin and etoposide]. Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:7 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Neuroendocrine; Cell Differentiation; Colonic Neoplasms; Combined Modality Therapy; Etoposide; Female; Humans; Liver Neoplasms	2011
Verticillin A overcomes apoptosis resistance in human colon carcinoma through DNA methylation-dependent upregulation of BNIP3. Cancer research, 2011, Nov-01, Volume: 71, Issue:21 Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cisplatin; Colonic Neoplasms; DNA Methylation; Drug Resistance, Neoplasm; Etoposide; Fas Ligand Protein; Female; Gene Expression Regulation, Neoplastic; Humans; Indoles; Liver Neoplasms; Membrane Proteins; Mice; Mice, Nude; Neoplasm Proteins; Promoter Regions, Genetic; Proto-Oncogene Proteins; Recombinant Proteins; RNA Interference; RNA, Small Interfering; TNF-Related Apoptosis-Inducing Ligand; Up-Regulation; Xenograft Model Antitumor Assays	2011
Cdx2 homeoprotein inhibits non-homologous end joining in colon cancer but not in leukemia cells. Nucleic acids research, 2012, Volume: 40, Issue:8 Topics: Antigens, Nuclear; CDX2 Transcription Factor; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; DNA End-Joining Repair; DNA-Activated Protein Kinase; DNA-Binding Proteins; Etoposide; Homeodomain Proteins; Humans; Ku Autoantigen; Leukemia; Protein Interaction Domains and Motifs; Transcription, Genetic; Tumor Suppressor Proteins	2012
Loss of giant obscurins promotes breast epithelial cell survival through apoptotic resistance. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2012, Volume: 26, Issue:7 Topics: Apoptosis; Base Sequence; Breast; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Nucleus; Cell Survival; Cell Transformation, Neoplastic; Colonic Neoplasms; DNA Damage; Epithelial Cells; Etoposide; Female; Gene Expression; Guanine Nucleotide Exchange Factors; Humans; Muscle Proteins; Protein Isoforms; Protein Serine-Threonine Kinases; Rho Guanine Nucleotide Exchange Factors; RNA, Messenger; RNA, Neoplasm; RNA, Small Interfering; Skin Neoplasms	2012
Quercetin enhances hypoxia-mediated apoptosis via direct inhibition of AMPK activity in HCT116 colon cancer. Apoptosis : an international journal on programmed cell death, 2012, Volume: 17, Issue:9 Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Cell Hypoxia; Cell Line, Tumor; Cisplatin; Colonic Neoplasms; Etoposide; Genes, Reporter; Humans; Hypoxia-Inducible Factor 1; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Quercetin; Signal Transduction; Xenograft Model Antitumor Assays	2012
Reformulation of etoposide with solubility-enhancing rubusoside. International journal of pharmaceutics, 2012, Sep-15, Volume: 434, Issue:1-2 Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Dimethyl Sulfoxide; Diterpenes, Kaurane; Drug Stability; Drug Storage; Etoposide; Excipients; Female; Glucosides; Humans; Light; Male; Microscopy, Electron, Transmission; Nanoparticles; Particle Size; Prostatic Neoplasms; Scattering, Radiation; Solubility; Temperature	2012
[A case of endocrine carcinoma of the cecum treated with CDDP/VP-16]. Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:8 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cecum; Cisplatin; Colonic Neoplasms; Endocrine Gland Neoplasms; Etoposide; Humans; Male; Tomography, X-Ray Computed	2012
Nuclear morphometric analysis (NMA): screening of senescence, apoptosis and nuclear irregularities. PloS one, 2012, Volume: 7, Issue:8 Topics: Annexins; Apoptosis; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cell Nucleus; Cellular Senescence; Cisplatin; Colonic Neoplasms; Etoposide; HeLa Cells; Humans; Mitosis; Phenotype; Principal Component Analysis; Vincristine	2012
Influence of G2 arrest on the cytotoxicity of DNA topoisomerase inhibitors toward human carcinoma cells with different p53 status. Acta biochimica Polonica, 2002, Volume: 49, Issue:1 Topics: Alkaloids; Antineoplastic Agents; Apoptosis; Camptothecin; Carcinoma; Cell Cycle; Colonic Neoplasms; Etoposide; Humans; Staurosporine; Topoisomerase Inhibitors; Tumor Suppressor Protein p53	2002
[Localization of primary small cell carcinoma with liver metastasis: a rare combination of colonic adenocarcinoma and undifferentiated small cell carcinoma]. Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2002, Volume: 73, Issue:8 Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Colectomy; Colon; Colonic Neoplasms; Docetaxel; Doxorubicin; Etoposide; Female; Humans; Immunohistochemistry; Liver; Liver Neoplasms; Neoplasms, Multiple Primary; Neoplasms, Unknown Primary; Paclitaxel; Taxoids; Time Factors; Vincristine	2002
Squamous cell carcinoma of the colon with an elevated serum squamous cell carcinoma antigen responding to combination chemotherapy. Clinical colorectal cancer, 2001, Volume: 1, Issue:1 Topics: Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cisplatin; Colonic Neoplasms; Etoposide; Fatal Outcome; Fluorouracil; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Serpins; Tomography, X-Ray Computed	2001
Antitumor activity of ER-37328, a novel carbazole topoisomerase II inhibitor. Molecular cancer therapeutics, 2002, Volume: 1, Issue:3 Topics: Amsacrine; Animals; Antineoplastic Agents; Carbazoles; Colonic Neoplasms; Cross-Linking Reagents; DNA, Neoplasm; Doxorubicin; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Female; Humans; In Vitro Techniques; Leukemia P388; Mice; Mice, Inbred C57BL; Pyrimidines; Topoisomerase II Inhibitors; Tumor Cells, Cultured	2002
Effects of ER-37328 on primary tumor, liver metastasis, and life span in a murine colon 38 orthotopic transplantation model. Molecular cancer therapeutics, 2003, Volume: 2, Issue:1 Topics: Animals; Carbazoles; Cell Division; Colonic Neoplasms; Etoposide; Female; Humans; Liver Neoplasms; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Neoplasm Metastasis; Pyrimidines; Survival Analysis; Time Factors; Transplantation, Heterologous	2003
A novel carbazole topoisomerase II poison, ER-37328: potent tumoricidal activity against human solid tumors in vitro and in vivo. Cancer science, 2003, Volume: 94, Issue:1 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Carbazoles; Colonic Neoplasms; DNA Damage; DNA, Neoplasm; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etoposide; Female; Humans; Lung Neoplasms; Macromolecular Substances; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Protein Binding; Pyrimidines; Stomach Neoplasms; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2003
Effect of apoptogenic stimuli on colon carcinoma cell lines with a different c-myc expression level. International journal of molecular medicine, 2003, Volume: 11, Issue:6 Topics: Antineoplastic Agents; Apoptosis; Bleomycin; Cell Line, Tumor; Cholecalciferol; Colonic Neoplasms; Doxorubicin; Endodeoxyribonucleases; Enzyme Activation; Etoposide; fas Receptor; Gene Expression; Genes, myc; Humans; Transfection	2003
Requirement of p53 targets in chemosensitization of colonic carcinoma to death ligand therapy. Proceedings of the National Academy of Sciences of the United States of America, 2003, Dec-09, Volume: 100, Issue:25 Topics: Adenoviridae; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Base Pair Mismatch; bcl-2-Associated X Protein; Camptothecin; Carcinoma; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cell Death; Cell Line; Cell Line, Tumor; Colonic Neoplasms; DNA Damage; DNA Repair; Enzyme Inhibitors; Etoposide; Flow Cytometry; Humans; Irinotecan; Luciferases; Membrane Glycoproteins; Mice; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; RNA, Small Interfering; Time Factors; TNF-Related Apoptosis-Inducing Ligand; Transcription, Genetic; Transfection; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53	2003
Increased immunogenicity of colon cancer cells by selective depletion of cytochrome C. Cancer research, 2004, Apr-15, Volume: 64, Issue:8 Topics: Animals; Apoptosis; Cisplatin; Colonic Neoplasms; Cytochromes c; DNA, Antisense; Down-Regulation; Doxorubicin; Etoposide; HCT116 Cells; HT29 Cells; Humans; Macrophages; Mice; Rats; Staurosporine; Transfection	2004
Stable suppression of the R2 subunit of ribonucleotide reductase by R2-targeted short interference RNA sensitizes p53(-/-) HCT-116 colon cancer cells to DNA-damaging agents and ribonucleotide reductase inhibitors. The Journal of biological chemistry, 2004, Jun-25, Volume: 279, Issue:26 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cisplatin; Colonic Neoplasms; Deoxyribonucleotides; DNA Damage; Down-Regulation; Doxorubicin; Enzyme Inhibitors; Etoposide; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Hydroxyurea; Intracellular Signaling Peptides and Proteins; Protein Subunits; Proto-Oncogene Proteins; Pyridines; Recombinant Proteins; Ribonucleotide Reductases; RNA, Small Interfering; Thiosemicarbazones; Tumor Suppressor Protein p53; Vincristine	2004
CD44 promotes resistance to apoptosis in human colon cancer cells. Experimental and molecular pathology, 2004, Volume: 77, Issue:1 Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Cell Adhesion; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; DNA Fragmentation; Drug Resistance, Neoplasm; Etoposide; Humans; Hyaluronan Receptors; Protein Isoforms; Transfection	2004
[Tumor lysis syndrome after chemotherapy for colon small cell carcinoma]. La Revue de medecine interne, 2004, Volume: 25, Issue:10 Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Colectomy; Colonic Neoplasms; Combined Modality Therapy; Etoposide; Female; Hearing Loss; Humans; Liver Neoplasms; Middle Aged; Postoperative Care; Tumor Lysis Syndrome	2004
Colonic T-cell leukemia mimicking colon carcinoma. American journal of surgery, 2005, Volume: 189, Issue:2 Topics: Aged; Antineoplastic Agents, Phytogenic; Carcinoma; Colectomy; Colonic Neoplasms; Diagnosis, Differential; Disease Progression; Etoposide; Humans; Leukemia, T-Cell; Male	2005
Mutant p53 gain of function: reduction of tumor malignancy of human cancer cell lines through abrogation of mutant p53 expression. Oncogene, 2006, Jan-12, Volume: 25, Issue:2 Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Proliferation; Cisplatin; Colonic Neoplasms; Colony-Forming Units Assay; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Mice; Mice, Nude; Mutation; Radiation-Sensitizing Agents; Transplantation, Heterologous; Tumor Cells, Cultured; Tumor Suppressor Protein p53	2006
Erybraedin C and bitucarpin A, two structurally related pterocarpans purified from Bituminaria bituminosa, induced apoptosis in human colon adenocarcinoma cell lines MMR- and p53-proficient and -deficient in a dose-, time-, and structure-dependent fashion Chemico-biological interactions, 2006, Feb-01, Volume: 159, Issue:2 Topics: Adenocarcinoma; Apoptosis; Cell Division; Cell Line, Tumor; Colonic Neoplasms; DNA-Binding Proteins; Dose-Response Relationship, Drug; Etoposide; Fabaceae; Humans; MutS Homolog 3 Protein; Pterocarpans; Structure-Activity Relationship; Thioguanine; Tumor Suppressor Protein p53	2006
hTERT: a novel endogenous inhibitor of the mitochondrial cell death pathway. Oncogene, 2006, Aug-03, Volume: 25, Issue:33 Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Catalytic Domain; Cell Line, Tumor; Cell Survival; Cisplatin; Colonic Neoplasms; DNA-Binding Proteins; Etoposide; fas Receptor; Female; Humans; Mitochondria; Mitomycin; Reactive Oxygen Species; Telomerase; Uterine Cervical Neoplasms	2006
Calreticulin exposure dictates the immunogenicity of cancer cell death. Nature medicine, 2007, Volume: 13, Issue:1 Topics: Animals; Anthracyclines; Antigens, Differentiation; Antineoplastic Agents; Apoptosis; Calreticulin; Cell Cycle Proteins; Cell Line, Tumor; Cell Membrane; Colonic Neoplasms; Dendritic Cells; Electrophoresis, Gel, Two-Dimensional; Etoposide; Immunoblotting; Mice; Mice, Inbred BALB C; Mice, Nude; Mitomycin; Neoplasms, Experimental; Phagocytosis; Protein Phosphatase 1; Protein Transport; Recombinant Proteins; RNA Interference	2007
Calreticulin exposure increases cancer immunogenicity. Nature biotechnology, 2007, Volume: 25, Issue:2 Topics: Animals; Anthracyclines; Antigens, Differentiation; Antineoplastic Agents; Apoptosis; Calreticulin; Cell Cycle Proteins; Cell Line, Tumor; Cell Membrane; Colonic Neoplasms; Dendritic Cells; Electrophoresis, Gel, Two-Dimensional; Etoposide; Immunoblotting; Mice; Mice, Inbred BALB C; Mice, Nude; Mitomycin; Neoplasms, Experimental; Phagocytosis; Protein Phosphatase 1; Protein Transport; Recombinant Proteins; RNA Interference	2007
Etoposide-resistant HT-29 human colon carcinoma cells during glucose deprivation are sensitive to piericidin A, a GRP78 down-regulator. Journal of cellular physiology, 2008, Volume: 215, Issue:1 Topics: Anti-Bacterial Agents; Antineoplastic Agents, Phytogenic; Caspase 7; Cell Death; Colonic Neoplasms; Down-Regulation; Drug Resistance, Neoplasm; Endoplasmic Reticulum Chaperone BiP; Enzyme Activation; Etoposide; Glucose; Heat-Shock Proteins; HT29 Cells; Humans; Molecular Chaperones; Pyridines; Up-Regulation	2008
Inhibition of MDR1 expression by retinol treatment increases sensitivity to etoposide (VP16) in human neoplasic cell line. Toxicology in vitro : an international journal published in association with BIBRA, 2008, Volume: 22, Issue:4 Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Colonic Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation; HT29 Cells; Humans; Polymerase Chain Reaction; Vitamin A	2008
Skin ulceration potential without therapeutic anticancer activity for epipodophyllotoxin commercial diluents. Investigational new drugs, 1983, Volume: 1, Issue:2 Topics: Adenocarcinoma; Animals; Cell Survival; Colonic Neoplasms; Etoposide; Humans; Leukemia P388; Leukemia, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Podophyllotoxin; Skin Ulcer; Solvents; Teniposide; Tumor Stem Cell Assay	1983
[Chemohyperthermic peritoneal perfusion and subtotal peritonectomy for peritonitis carcinomatosa in gastroenteric cancer]. Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:11 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Combined Modality Therapy; Etoposide; Female; Humans; Hyperthermia, Induced; Male; Middle Aged; Mitomycin; Neoplasm Invasiveness; Perfusion; Peritoneal Lavage; Peritoneal Neoplasms; Peritoneum; Peritonitis; Stomach Neoplasms	1995
Characteristics of the inhibitory effect of mitoxantrone and pirarubicin on lung metastases of colon carcinoma 26. Japanese journal of cancer research : Gann, 1995, Volume: 86, Issue:9 Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cell Division; Colonic Neoplasms; Dose-Response Relationship, Drug; Doxorubicin; Drug Screening Assays, Antitumor; Endothelium, Vascular; Etoposide; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Mitoxantrone; Neoplasm Transplantation; Neovascularization, Pathologic; Rats	1995
Enhanced therapeutic effects of anti-tumour agents against growth and metastasis of colon carcinoma 26 when given in combination with interferon and interleukin-2. Clinical & experimental metastasis, 1994, Volume: 12, Issue:6 Topics: Animals; Carcinoma; Cisplatin; Colonic Neoplasms; Drug Therapy, Combination; Etoposide; Interferon-beta; Interleukin-2; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Neoplasm Metastasis	1994
Chemotherapy with [SP-4-3-(R)]-[1,1-cyclobutanedicarboxylato(2-)](2- methyl-1,4-butanediamine-N,N')platinum (CI-973, NK121) in combination with standard agents against murine tumors in vivo. Cancer research, 1994, Aug-15, Volume: 54, Issue:16 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Colonic Neoplasms; Cyclophosphamide; Doxorubicin; Drug Screening Assays, Antitumor; Etoposide; Ifosfamide; Leukemia P388; Mammary Neoplasms, Animal; Melanoma, Experimental; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Mitomycin; Sarcoma, Experimental; Vinblastine	1994
Structure-activity relationships of VP-16 analogues. Cancer chemotherapy and pharmacology, 1994, Volume: 34 Suppl Topics: Cell Line; Cell Survival; Colonic Neoplasms; DNA Topoisomerases, Type II; DNA, Viral; Etoposide; Humans; Kinetics; Molecular Structure; Structure-Activity Relationship; Topoisomerase II Inhibitors; Tumor Cells, Cultured	1994
Reversal of etoposide resistance in non-P-glycoprotein expressing multidrug resistant tumor cell lines by novobiocin. Cancer research, 1993, Nov-15, Volume: 53, Issue:22 Topics: Adenocarcinoma; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Colonic Neoplasms; DNA Topoisomerases, Type II; DNA, Neoplasm; Drug Resistance; Etoposide; Flow Cytometry; Humans; Leukemia L1210; Lung Neoplasms; Membrane Glycoproteins; Mice; Novobiocin; Tumor Cells, Cultured	1993
Different modes of cell-killing action between DNA topoisomerase I and II inhibitors revealed by kinetic analysis. Japanese journal of cancer research : Gann, 1994, Volume: 85, Issue:2 Topics: Amsacrine; Antineoplastic Agents; Camptothecin; Carbazoles; Cell Cycle; Colonic Neoplasms; Diterpenes; DNA Replication; Dose-Response Relationship, Drug; Etoposide; Flow Cytometry; G2 Phase; Humans; Indoles; Mitosis; Quinones; S Phase; Teniposide; Time Factors; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Tumor Stem Cell Assay	1994
Etoposide-resistant human colon and lung adenocarcinoma cell lines exhibit sensitivity to homoharringtonine. Cancer chemotherapy and pharmacology, 1993, Volume: 33, Issue:2 Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Colonic Neoplasms; Drug Resistance; Etoposide; Harringtonines; Homoharringtonine; Humans; Lung Neoplasms; Tumor Cells, Cultured	1993
Stereo (C7)-dependent topoisomerase II inhibition and tumor growth suppression by a new quinolone, BO-2367. Japanese journal of cancer research : Gann, 1993, Volume: 84, Issue:7 Topics: Animals; Anti-Infective Agents; Carcinoma; Colonic Neoplasms; DNA Topoisomerases, Type II; DNA, Neoplasm; DNA, Superhelical; Drug Screening Assays, Antitumor; Enzyme Induction; Etoposide; Female; Fluoroquinolones; Leukemia L1210; Leukemia P388; Mice; Mice, Inbred Strains; Quinolones; Stereoisomerism; Topoisomerase II Inhibitors	1993
Topoisomerase II inhibition differentially modulates Caco-2 intestinal epithelial cell phenotype. Biochemical and biophysical research communications, 1996, Feb-06, Volume: 219, Issue:1 Topics: Alkaline Phosphatase; Analysis of Variance; Antineoplastic Agents, Phytogenic; Caco-2 Cells; Cell Differentiation; Cell Division; Cell Movement; Colonic Neoplasms; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelium; Etoposide; Humans; Kinetics; Microvilli; Phenotype; Topoisomerase II Inhibitors; Tumor Cells, Cultured	1996
Antitumor activity of a novel podophyllotoxin derivative (TOP-53) against lung cancer and lung metastatic cancer. Cancer research, 1996, Jun-15, Volume: 56, Issue:12 Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Colonic Neoplasms; DNA, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Nude; Neoplasms, Experimental; Specific Pathogen-Free Organisms; Topoisomerase II Inhibitors; Tumor Cells, Cultured	1996
Comparison of costs for infusion versus bolus chemotherapy administration: analysis of five standard chemotherapy regimens in three common tumors--Part one. Model projections for cost based on charges. Cancer, 1996, Jul-15, Volume: 78, Issue:2 Topics: Antibiotics, Antineoplastic; Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colonic Neoplasms; Costs and Cost Analysis; Cyclophosphamide; Disposable Equipment; Doxorubicin; Drug Costs; Etoposide; Fees, Medical; Fees, Pharmaceutical; Female; Fluorouracil; Humans; Infusions, Intravenous; Injections, Intravenous; Leucovorin; Lymphoma, Non-Hodgkin; Methotrexate; Models, Economic; Prednisone; Survival Rate; Vincristine	1996
[Chemohyperthermic peritoneal perfusion and high-dose chemotherapy followed by peripheral blood stem cell transplantation in advanced colon cancer--a case report]. Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:11 Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Colonic Neoplasms; Combined Modality Therapy; Cyclophosphamide; Drug Administration Schedule; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Hyperthermia, Induced; Liver Neoplasms; Lung Neoplasms; Middle Aged; Mitomycin; Perfusion; Peritoneum	1996
An apoptotic response to photodynamic therapy with endogenous protoporphyrin in vivo. Journal of photochemistry and photobiology. B, Biology, 1996, Volume: 35, Issue:3 Topics: Animals; Apoptosis; Carmustine; Colonic Neoplasms; DNA Fragmentation; Doxorubicin; Etoposide; Mice; Paclitaxel; Photochemotherapy; Protoporphyrins	1996
Induction of p53-independent apoptosis associated with G2M arrest following DNA damage in human colon cancer cell lines. Japanese journal of cancer research : Gann, 1997, Volume: 88, Issue:1 Topics: Apoptosis; Cell Survival; Colonic Neoplasms; DNA Damage; DNA Fragmentation; Etoposide; G2 Phase; Gamma Rays; Humans; Mitosis; Tumor Cells, Cultured; Tumor Suppressor Protein p53	1997
The multidrug resistance-associated protein gene confers drug resistance in human gastric and colon cancers. Japanese journal of cancer research : Gann, 1996, Volume: 87, Issue:12 Topics: Antineoplastic Agents; Camptothecin; Cisplatin; Colonic Neoplasms; Doxorubicin; Etoposide; Genes, MDR; Humans; Irinotecan; Mitomycin; Polymerase Chain Reaction; RNA, Messenger; Stomach Neoplasms; Tumor Cells, Cultured; Verapamil; Vincristine	1996
Inhibition of p53-mediated transactivation and cell cycle arrest by E1A through its p300/CBP-interacting region. Oncogene, 1997, Mar-06, Volume: 14, Issue:9 Topics: Acetyltransferases; Adenovirus E1A Proteins; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Cycle Proteins; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA Damage; DNA, Neoplasm; Doxorubicin; Enzyme Inhibitors; Etoposide; Histone Acetyltransferases; Humans; Lung Neoplasms; p300-CBP Transcription Factors; Retinoblastoma; Transcription Factors; Transcriptional Activation; Tumor Cells, Cultured; Tumor Suppressor Protein p53	1997
Topotecan increases topoisomerase IIalpha levels and sensitivity to treatment with etoposide in schedule-dependent process. Cancer research, 1997, Apr-15, Volume: 57, Issue:8 Topics: Animals; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Screening Assays, Antitumor; Enzyme Induction; Etoposide; Female; Humans; Isoenzymes; Mice; Mice, Nude; Neoplasm Proteins; Topoisomerase II Inhibitors; Topotecan; Transplantation, Heterologous; Tumor Cells, Cultured; Up-Regulation	1997
Loss of DNA mismatch repair: effects on the rate of mutation to drug resistance. Journal of the National Cancer Institute, 1997, Oct-15, Volume: 89, Issue:20 Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Carrier Proteins; Cell Survival; Chromosome Mapping; Chromosomes, Human, Pair 2; Chromosomes, Human, Pair 3; Cisplatin; Colonic Neoplasms; DNA Repair; Drug Resistance, Multiple; Etoposide; Humans; Mutagenesis; MutL Protein Homolog 1; Neoplasm Proteins; Nuclear Proteins; Paclitaxel; Repetitive Sequences, Nucleic Acid; Tumor Cells, Cultured	1997
Antitumor activity of a novel quinoline derivative, TAS-103, with inhibitory effects on topoisomerases I and II. Japanese journal of cancer research : Gann, 1997, Volume: 88, Issue:10 Topics: Adenocarcinoma; Aminoquinolines; Animals; Antineoplastic Agents; Camptothecin; Cisplatin; Colonic Neoplasms; DNA; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Etoposide; Humans; Indenes; Indoles; Irinotecan; Lung Neoplasms; Male; Melanoma; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Pyridines; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured	1997
Potential role for cathepsin D in p53-dependent tumor suppression and chemosensitivity. Oncogene, 1998, Apr-30, Volume: 16, Issue:17 Topics: Animals; Apoptosis; Cathepsin D; Cell Line; Colonic Neoplasms; DNA Damage; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Female; Fibroblasts; Genes, p53; Humans; Mice; Ovarian Neoplasms; Pepstatins; RNA, Messenger; Transcriptional Activation; Tumor Cells, Cultured; Up-Regulation	1998
Upregulation of CASP genes in human tumor cells undergoing etoposide-induced apoptosis. Oncogene, 1998, Jun-04, Volume: 16, Issue:22 Topics: Apoptosis; Bone Marrow; Caspase 2; Caspase 3; Caspase 7; Caspases; Colonic Neoplasms; Cysteine Endopeptidases; Etoposide; HL-60 Cells; HT29 Cells; Humans; Leukemia, Myeloid, Acute; Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured; Up-Regulation	1998
Evaluation of irinotecan in combination with 5-fluorouracil or etoposide in xenograft models of colon adenocarcinoma and rhabdomyosarcoma. Clinical cancer research : an official journal of the American Association for Cancer Research, 1996, Volume: 2, Issue:1 Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Etoposide; Female; Fluorouracil; Humans; Irinotecan; Mice; Mice, Inbred CBA; Neoplasm Transplantation; Rhabdomyosarcoma; Transplantation, Heterologous	1996
Synergistic cytotoxicity, apoptosis and protein-linked DNA breakage by etoposide and camptothecin in human U87 glioma cells: dependence on tyrosine phosphorylation. Journal of neuro-oncology, 1999, Volume: 41, Issue:3 Topics: Brain Neoplasms; Camptothecin; Cell Survival; Colonic Neoplasms; DNA Damage; Drug Synergism; Etoposide; Glioblastoma; Glioma; Humans; Mitotic Index; Phosphotyrosine; Tumor Cells, Cultured; Tumor Suppressor Protein p53	1999
Schedule-dependent interactions between paclitaxel and etoposide in human carcinoma cell lines in vitro. Cancer chemotherapy and pharmacology, 1999, Volume: 44, Issue:5 Topics: Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Division; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Interactions; Drug Screening Assays, Antitumor; Etoposide; Female; Humans; Lung Neoplasms; Ovarian Neoplasms; Paclitaxel; Time Factors; Tumor Cells, Cultured	1999
Homocamptothecin, an E-ring-modified camptothecin, exerts more potent antiproliferative activity than other topoisomerase I inhibitors in human colon cancers obtained from surgery and maintained in vitro under histotypical culture conditions. Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:4 Topics: Antineoplastic Agents; Biopsy; Camptothecin; Cell Division; Colon; Colonic Neoplasms; Culture Techniques; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Inhibitors; Etoposide; Humans; Irinotecan; Thymidine; Topoisomerase I Inhibitors; Topotecan; Tritium; Tumor Cells, Cultured	2000
Antitumor effect of oxycellulose as a hemostatic during operation. Cancer biotherapy & radiopharmaceuticals, 1998, Volume: 13, Issue:6 Topics: Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; DNA, Neoplasm; Erythrocytes; Etoposide; Female; Fibrosarcoma; Hemostatics; Hypromellose Derivatives; Injections, Intraperitoneal; Liver Neoplasms, Experimental; Methylcellulose; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mitomycin; Tumor Cells, Cultured	1998
Differential expression of sphingolipids in MRP1 overexpressing HT29 cells. International journal of cancer, 2000, Jul-15, Volume: 87, Issue:2 Topics: Antineoplastic Agents; ATP-Binding Cassette Transporters; Cell Survival; Ceramides; Colchicine; Colonic Neoplasms; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Etoposide; Fluoresceins; Galactosylceramides; Glucosylceramides; HT29 Cells; Humans; Immunoblotting; Immunohistochemistry; Microscopy, Confocal; Microtubules; Mitosis; Multidrug Resistance-Associated Proteins; Paclitaxel; Propionates; Quinolines; Signal Transduction; Sphingolipids; Vincristine	2000
Changes in subcellular distribution of topoisomerase IIalpha correlate with etoposide resistance in multicell spheroids and xenograft tumors. Cancer research, 2000, Oct-15, Volume: 60, Issue:20 Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; Colonic Neoplasms; Cricetinae; Cricetulus; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Resistance, Neoplasm; Etoposide; Female; Fibroblasts; Glioma; Humans; Isoenzymes; Mice; Mice, Inbred NOD; Mice, SCID; Spheroids, Cellular; Subcellular Fractions; Tumor Cells, Cultured; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays	2000
[Three cases of liver metastasis of colon cancer responding to systemic combination chemotherapy utilizing CPT-11]. Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:14 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Colonic Neoplasms; Doxorubicin; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Irinotecan; Liver Neoplasms; Male; Tegafur; Uracil	2000
Reversal of LRP-associated drug resistance in colon carcinoma SW-620 cells. International journal of cancer, 2001, Jan-01, Volume: 91, Issue:1 Topics: Alkaloids; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Benzylisoquinolines; Butyrates; Carcinoma; Cell Nucleus; Colonic Neoplasms; Coloring Agents; Cyclic P-Oxides; Cytoplasm; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Humans; Microscopy, Fluorescence; Neoplasm Proteins; Nicotinic Acids; RNA, Catalytic; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured; Vault Ribonucleoprotein Particles	2001
Antitumor activity of XR5944, a novel and potent topoisomerase poison. Anti-cancer drugs, 2001, Volume: 12, Issue:4 Topics: Aminoquinolines; Animals; Antigens, Neoplasm; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Colonic Neoplasms; DNA; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Indenes; Inhibitory Concentration 50; Injections, Intraperitoneal; Injections, Intravenous; Isoenzymes; Lung Neoplasms; Mice; Mice, Nude; Phenazines; Remission Induction; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Topotecan; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2001
Thymidine incorporation is highly predictive of colony formation and can be used for high-throughput screening. BioTechniques, 2001, Volume: 30, Issue:5 Topics: Animals; Antineoplastic Agents; Cell Division; Cell Survival; Chickens; CHO Cells; Colonic Neoplasms; Colony-Forming Units Assay; Cricetinae; Drug Screening Assays, Antitumor; Etoposide; Humans; Hydroxyurea; Kidney Neoplasms; Lung Neoplasms; Paclitaxel; Sensitivity and Specificity; Thymidine; Tritium; Tumor Cells, Cultured	2001
p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents. Oncogene, 2001, Jun-07, Volume: 20, Issue:26 Topics: Adenocarcinoma; Alleles; Amino Acid Chloromethyl Ketones; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Benzothiazoles; Butyrates; Cisplatin; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Proteinase Inhibitors; Demecolcine; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Fluorouracil; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; Intracellular Membranes; Membrane Potentials; Mitochondria; Neoplasm Proteins; Recombination, Genetic; Resveratrol; Stilbenes; Thiazoles; Toluene; Tumor Cells, Cultured; Tumor Suppressor Protein p53	2001
Neither p21WAF1 nor 14-3-3sigma prevents G2 progression to mitotic catastrophe in human colon carcinoma cells after DNA damage, but p21WAF1 induces stable G1 arrest in resulting tetraploid cells. Cancer research, 2001, Oct-15, Volume: 61, Issue:20 Topics: 14-3-3 Proteins; Antineoplastic Agents; Biomarkers, Tumor; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA Damage; DNA, Neoplasm; Doxorubicin; Etoposide; Exonucleases; Exoribonucleases; G2 Phase; Humans; Microscopy, Confocal; Mitosis; Mitotic Index; Neoplasm Proteins; Nocodazole; Ploidies; Proteins; Tumor Cells, Cultured	2001
Modification of the sensitivity to cisplatin with c-myc over-expression or down-regulation in colon cancer cells. Anti-cancer drugs, 2001, Volume: 12, Issue:10 Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Division; Cisplatin; Colonic Neoplasms; DNA Damage; DNA Primers; Drug Resistance, Neoplasm; Etoposide; Humans; In Situ Nick-End Labeling; Oligonucleotides, Antisense; Proto-Oncogene Proteins c-myc; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Transfection; Tumor Cells, Cultured	2001
Lactic Acidosis in Non-Hodgkin's Lymphoma and response to Chemotherapy. Haematologica, 2002, Volume: 87, Issue:2 Topics: Acidosis, Lactic; Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Colonic Neoplasms; Cyclophosphamide; Doxorubicin; Etoposide; Fatal Outcome; Humans; Lactates; Liver; Lymphoma, Large B-Cell, Diffuse; Male; Neoplasms, Second Primary; Prednisone; Sodium Bicarbonate; Vincristine	2002
Tumor-cell resistance to death receptor--induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax. Nature medicine, 2002, Volume: 8, Issue:3 Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; BH3 Interacting Domain Death Agonist Protein; Camptothecin; Carrier Proteins; Caspase 8; Caspase 9; Caspases; Colonic Neoplasms; Enzyme Activation; Etoposide; Fas-Associated Death Domain Protein; Female; Flow Cytometry; Humans; Membrane Glycoproteins; Mice; Mice, Nude; Mitochondria; Mutation; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Random Allocation; Receptors, Tumor Necrosis Factor; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand; Transplantation, Heterologous; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha	2002
Stromal extracellular matrix reduces chemotherapy-induced apoptosis in colon cancer cell lines. Clinical & experimental metastasis, 2002, Volume: 19, Issue:1 Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; bcl-X Protein; Camptothecin; Collagen; Colonic Neoplasms; Enzyme Inhibitors; Etoposide; Extracellular Matrix; Extracellular Matrix Proteins; Fibroblasts; Fibronectins; Fluorouracil; Genes, bcl-2; Hepatocytes; Humans; Neoplasm Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Inbred F344; Rats, Wistar; Stromal Cells; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured	2002
[Clinical and therapeutic study (phase II) using VP-16/213 and methyl-CCNU in patients with inoperable, recurring or metastasizing carcinomas of the gastriointestinal tract]. Onkologie, 1978, Volume: 1, Issue:5 Topics: Adult; Aged; Colonic Neoplasms; Drug Therapy, Combination; Etoposide; Female; Follow-Up Studies; Humans; Lomustine; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Nitrosourea Compounds; Podophyllotoxin; Stomach Neoplasms; Terminal Care; Time Factors	1978
Sequential administration of camptothecin and etoposide circumvents the antagonistic cytotoxicity of simultaneous drug administration in slowly growing human colon carcinoma HT-29 cells. European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A, Issue:4-5 Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Division; Colonic Neoplasms; DNA Damage; DNA, Neoplasm; DNA, Single-Stranded; Drug Administration Schedule; Drug Interactions; Etoposide; Humans; Kinetics; RNA, Neoplasm; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured	1992
Growth fraction measured using the comet assay. Cell proliferation, 1992, Volume: 25, Issue:5 Topics: Animals; Bromodeoxyuridine; Cell Division; Colonic Neoplasms; DNA Damage; DNA, Neoplasm; Etoposide; Fluorescent Antibody Technique; Humans; Mice; Mice, Nude; Microscopy, Fluorescence; Tumor Cells, Cultured	1992
[Intraperitoneal chemotherapy of metastatic ovarian cancer]. Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:10 Suppl Topics: Cisplatin; Colonic Neoplasms; Drug Administration Schedule; Etoposide; Female; Fluorouracil; Humans; Infusions, Parenteral; Middle Aged; Ovarian Neoplasms; Stomach Neoplasms	1992
Pharmacologic interactions between the resistance-modifying cyclosporine SDZ PSC 833 and etoposide (VP 16-213) enhance in vivo cytostatic activity and toxicity. International journal of cancer, 1992, May-28, Volume: 51, Issue:3 Topics: Adenocarcinoma; Adult; Animals; Colonic Neoplasms; Cyclosporins; Drug Administration Schedule; Drug Interactions; Drug Screening Assays, Antitumor; Etoposide; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Specific Pathogen-Free Organisms	1992
In vitro and in vivo modulation of multi-drug resistance with amiodarone. International journal of cancer, 1991, Jun-19, Volume: 48, Issue:4 Topics: Adult; Amiodarone; Biological Transport; Carcinoma, Small Cell; Cell Line; Cell Survival; Colonic Neoplasms; DNA Damage; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Etoposide; Female; Humans; Kinetics; Lung Neoplasms; Male; Neoplasms; Tumor Stem Cell Assay; Vincristine	1991
Potentiation by phenylbisbenzimidazoles of cytotoxicity of anticancer drugs directed against topoisomerase II. European journal of cancer (Oxford, England : 1990), 1990, Volume: 26, Issue:5 Topics: Acridines; Amsacrine; Animals; Antineoplastic Agents; Benzimidazoles; Bisbenzimidazole; Colonic Neoplasms; Doxorubicin; Drug Synergism; Etoposide; Fluorescent Dyes; Leukemia L1210; Lung Neoplasms; Melanoma; Mice; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Tumor Stem Cell Assay	1990
Mechanisms of resistance to etoposide and teniposide in acquired resistant human colon and lung carcinoma cell lines. Cancer research, 1991, Oct-01, Volume: 51, Issue:19 Topics: Adenocarcinoma; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Cell Line; Colonic Neoplasms; DNA; DNA Damage; DNA Probes; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Etoposide; Humans; Immunoblotting; Lung Neoplasms; Membrane Glycoproteins; Molecular Sequence Data; Neoplasm Proteins; Porfiromycin; RNA; Teniposide	1991
Differential induction of secondary DNA fragmentation by topoisomerase II inhibitors in human tumor cell lines with amplified c-myc expression. Cancer research, 1991, Dec-01, Volume: 51, Issue:23 Pt 1 Topics: Adenocarcinoma; Colonic Neoplasms; DNA Damage; DNA Repair; DNA, Neoplasm; Etoposide; Gene Amplification; Genes, myc; Humans; Leukemia, Promyelocytic, Acute; Teniposide; Tumor Cells, Cultured; Tumor Stem Cell Assay	1991
[Antitumor activity by long-term administration of low-dose etoposide]. Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:6 Topics: Adenocarcinoma; Administration, Oral; Animals; Colonic Neoplasms; Etoposide; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL	1991
[Intra-hepato-arterial infusion chemotherapy using catheter inserted and placed in hepatic artery via the left radial artery on liver malignancy]. Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:3 Pt 1 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Catheterization; Cisplatin; Colonic Neoplasms; Embolization, Therapeutic; Etoposide; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Mitomycin; Mitomycins; Stomach Neoplasms	1990
Infusion of high doses of undiluted etoposide through central venous catheters during preparation for bone marrow transplantation. Cancer investigation, 1990, Volume: 8, Issue:1 Topics: Adenocarcinoma; Adolescent; Adult; Aged; Bone Marrow Transplantation; Carcinoma, Non-Small-Cell Lung; Catheterization, Central Venous; Colonic Neoplasms; Drug Administration Schedule; Etoposide; Humans; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma; Middle Aged; Neoplasms	1990
Antitumor effects of antibody enzyme conjugates in combination with prodrugs. Frontiers of radiation therapy and oncology, 1990, Volume: 24 Topics: Alkaline Phosphatase; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Cattle; Colonic Neoplasms; Combined Modality Therapy; Etoposide; Humans; Immunotoxins; Lung Neoplasms; Mice; Mitomycins; Organophosphorus Compounds; Prodrugs; Tumor Cells, Cultured	1990
Preclinical antitumor activity of a soluble etoposide analog, BMY-40481-30. Investigational new drugs, 1990, Volume: 8 Suppl 1 Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Drug Screening Assays, Antitumor; Etoposide; Humans; Leukemia L1210; Leukemia P388; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Neoplasm Transplantation; Organophosphorus Compounds; Tumor Cells, Cultured	1990
[A study of combined chemotherapy with MMC, ADM, CDDP, VP-16 and 5'DFUR (MAC-VD) in advanced cancers of digestive organs]. Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:7 Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Floxuridine; Gallbladder Neoplasms; Humans; Infusions, Intravenous; Male; Middle Aged; Mitomycin; Mitomycins; Splenic Neoplasms; Stomach Neoplasms	1989
Overexpression of DNA replication and repair enzymes in cisplatin-resistant human colon carcinoma HCT8 cells and circumvention by azidothymidine. Cancer communications, 1989, Volume: 1, Issue:4 Topics: Cell Line; Cisplatin; Colonic Neoplasms; DNA Polymerase I; DNA Polymerase II; DNA Repair; DNA Replication; Drug Resistance; Etoposide; Floxuridine; Fluorouracil; Humans; Methotrexate; Tetrahydrofolate Dehydrogenase; Thymidine Kinase; Thymidylate Synthase; Tumor Cells, Cultured; Zidovudine	1989
Anti-tumor effects of antibody-alkaline phosphatase conjugates in combination with etoposide phosphate. Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:13 Topics: Alkaline Phosphatase; Animals; Antibodies, Monoclonal; Biotransformation; Colonic Neoplasms; Etoposide; Female; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Pharmaceutical Preparations; Prodrugs; Transplantation, Heterologous; Tumor Cells, Cultured	1988
Phase I study of high-dose cytosine arabinoside and etoposide in patients with advanced malignancies. Cancer chemotherapy and pharmacology, 1987, Volume: 19, Issue:3 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Cytarabine; Drug Evaluation; Etoposide; Female; Genital Neoplasms, Female; Head and Neck Neoplasms; Hematologic Diseases; Humans; Kidney Neoplasms; Lymphoma, Non-Hodgkin; Middle Aged	1987
[The antitumor activity of intraperitoneally- or orally-administered etoposide in animals and its administration-schedule dependency]. Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:12 Topics: Adenocarcinoma; Administration, Oral; Animals; Carcinoma, Ehrlich Tumor; Colonic Neoplasms; Drug Administration Schedule; Etoposide; Female; Leukemia, Experimental; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Podophyllotoxin	1985