etoposide has been researched along with Chromosomal Translocation in 147 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (1.36) | 18.7374 |
| 1990's | 54 (36.73) | 18.2507 |
| 2000's | 54 (36.73) | 29.6817 |
| 2010's | 32 (21.77) | 24.3611 |
| 2020's | 5 (3.40) | 2.80 |
| Authors | Studies |
|---|---|
| Morotomi-Yano, K; Yano, KI | 1 |
| Alexeyevsky, DA; Artemov, AV; Gavrilov, AA; Lomov, NA; Razin, SV; Rubtsov, MA; Ulianov, SV; Viushkov, VS | 1 |
| Ando, T; Katsuya, H; Kidoguchi, K; Kimura, S; Kishimori, C; Kizuka-Sano, H; Kubota, Y; Nishioka, A; Ohno, H; Yamaguchi, K | 1 |
| Berman, C; Emmanuel, F; Goodenow, D; Richardson, C; Sahyouni, M | 1 |
| Behrens, YL; Ganser, A; Göhring, G; Kreipe, HH; Schünemann, C; Thol, F | 1 |
| Barth, TFE; Bernd, HW; Cogliatti, S; Feller, AC; Hansmann, ML; Hartmann, S; Horn, H; Hummel, M; Klapper, W; Lenz, G; Lenze, D; Löffler, M; Möller, P; Ott, G; Pfreundschuh, M; Rosenwald, A; Schmitz, N; Scott, DW; Staiger, AM; Stein, H; Szczepanowski, M; Trümper, L; Ziepert, M | 1 |
| Fuji, S; Ohno, N; Shimada, N; Suzuki, Y; Tanosaki, R; Tojo, A; Uchimaru, K; Yuji, K | 1 |
| Chen, SN; Dai, HP; Ding, C; Drexler, HG; Macleod, RAF; Nagel, S; Sun, AN; Wu, DP | 1 |
| Adams, T; Al-Kateb, H; Anwer, F; Fuchs, D; Johnstone, L; Lau, BM; McGhan, L; Shadoan, PK | 1 |
| Fukuto, A; Harata, M; Horikoshi, Y; Ikura, M; Ikura, T; Kanaar, R; Kinomura, A; Oma, Y; Shi, L; Sun, J; Tashiro, S | 1 |
| Bishop, MR; Cohen, KS; Godfrey, JK; Karmali, R; Karrison, T; Kline, JP; Nabhan, C; Rapoport, AP; Smith, SM; Stadler, WM; Venugopal, P | 1 |
| Hirakawa, Y; Iwai, T; Kawaji, Y; Kobayashi, T; Kuriyama, K; Kuroda, J; Muramatsu, A; Nagata, H; Ohshiro, M; Uchiyama, H; Urata, Y | 1 |
| Caldecott, KW; Callen, E; Canela, A; Day, A; Huang, SN; Maman, Y; Nussenzweig, A; Peters, JM; Pommier, Y; Tang, W; Wong, N; Wutz, G; Zagnoli-Vieira, G | 1 |
| Abramson, JS | 1 |
| Sun, B; Wang, Y; Xu, X; Zhang, L; Zhang, Q; Zhang, Y | 1 |
| Alexeevski, AV; Alexeyevsky, DA; Glukhov, SI; Iarovaia, OV; Razin, SV; Rubtsov, MA | 1 |
| Austin, CA; Cowell, IG; Smith, KA; Sondka, Z; Zhang, Y | 1 |
| Costello, BA; Dronca, RS; French, CA; Hilton, J; Marks, RS; Molina, JR; Nerby, CL; Parikh, SA; Peddareddigari, VG; Roden, AC; Shapiro, GI | 1 |
| Amin, HM; Ok, CY; Wang, SA | 1 |
| Jacobson, C; LaCasce, A | 1 |
| Basso, G; Beqiri, V; Bisio, V; Buldini, B; Fagioli, F; Locatelli, F; Manara, E; Masetti, R; Pession, A; Pigazzi, M; Putti, MC; Rizzari, C; Rondelli, R; Tregnago, C | 1 |
| Gill Super, HJ | 1 |
| Fujimi, A; Hamaguchi, K; Hashimoto, A; Hayasaka, N; Iwasaki, S; Kamihara, Y; Kanisawa, Y; Kato, J; Matsumoto, T; Minami, S; Nakajima, C; Okuda, T; Shibata, T; Yamada, S | 1 |
| Alonzo, T; Auvrignon, A; Balwierz, W; Beverloo, HB; Bongers, M; Cloos, J; Creutzig, U; De Moerloose, B; Dworzak, M; Forestier, E; Fynn, A; Gibson, B; Harrison, CJ; Hirsch, B; Johnston, D; Kaspers, G; Klein, K; Lee, V; Pession, A; Popa, A; Raimondi, S; Reedijk, A; Reinhardt, D; Rubnitz, J; Salgado, C; Taga, T; Tawa, A; Zapotocky, M; Zeller, B; Zimmerman, M | 1 |
| Almadana Pacheco, V; Benito Bernáldez, C; Romero Muñoz, C | 1 |
| Cornelissen, JJ; Schnog, JB; Van Hest, RM; Van't Veer, MB | 1 |
| Bourgeois, JM; Hodson, I; Macdonald, P; Midia, M; Mullah-Ali, A; Portwine, C; Ramsay, JA | 1 |
| Burke, BA; Carroll, M; Dierov, J; Padilla-Nash, H; Putt, ME; Ried, T; Sanchez, PV | 1 |
| Brassesco, MS; Camparoto, ML; Gras, DE; Martinez-Rossi, NM; Montaldi, AP; Sakamoto-Hojo, ET; Scrideli, CA; Tone, LG | 1 |
| Barretto, NN; Bennett, CA; Hemenway, CS; Winters, AC | 1 |
| Chen, WT; Choy, CO; Chu, JS; Chu, KL; Din, R; Hsu, HL; Huang, SF; Kasiappan, R; Liu, HP; Shih, HJ; Shu, CL | 1 |
| Al Balushi, Z; Bulduc, S; Lallier, M; Mulleur, C | 1 |
| Kurokawa, M; Nagai, S; Nannya, Y; Takahashi, T | 1 |
| Chen, X; Lei, P; Li, Y; Liu, L; Zhai, Y; Zhang, Y | 1 |
| Harata, M; Ikura, T; Kanaar, R; Kinomura, A; Kono, K; Mizutani, S; Oma, Y; Shima, H; Sun, J; Suzuki, H; Tashiro, S | 1 |
| Ozdemirli, M; Sathiyamoorthy, S; Shad, A | 1 |
| de Meis, E; Dobbin, JA; Emerenciano, M; Macedo-Silva, ML; Marschalek, R; Meyer, C; Pombo-de-Oliveira, MS | 1 |
| Akao, Y; Horiike, S; Kobayashi, S; Kobayashi, T; Kuroda, J; Matsumoto, Y; Nagoshi, H; Nishida, K; Sasaki, N; Shimura, Y; Taki, T; Taniwaki, M; Tsutsumi, Y; Yamamoto, M | 1 |
| Amant, F; Coenegrachts, L; Debiec-Rychter, M; Decloedt, J; Moerman, P; Tousseyn, T | 1 |
| Bain, BJ; Innes, A; May, PC; Pavlů, J | 1 |
| Ferreri, AJ; Govi, S; Pileri, SA; Savage, KJ | 1 |
| Adachi, N; Austin, CA; Cowell, IG; Jackson, GH; Lee, KC; Manville, CM; Padget, K; Rance, HA; Sidorczuk-Lesthuruge, M; Smith, K; Sondka, Z | 1 |
| Creutzig, U; Reinhardt, D; Sander, A; Von Neuhoff, C | 1 |
| Austin, CA; Cowell, IG | 1 |
| Hamaguchi, H; Morita, Y; Nagata, K; Yamamoto, K | 1 |
| Creutzig, U; Hählen, K; Harbott, J; Huismans, DR; Kaspers, GJ; Pieters, R; Slater, RM; Veerman, AJ; Zimmermann, M; Zwaan, CM | 1 |
| Borker, A; Ode, D; Yu, L | 1 |
| Cheshenko, N; Herold, BC; Lehrer, RI; Sinha, S | 1 |
| Takeuchi, M; Yoshida, I | 1 |
| Antonelli, A; Biroccio, A; Elli, R; Gabellini, C; Marcucci, L; Nigro, G; Petrinelli, P; Russo, G; Zupi, G | 1 |
| Kondo, T; Mikami, M; Nakanishi, H; Otsuki, T; Suemori, S; Suetsugu, Y; Sugihara, T; Tsujioka, T; Wada, H; Yamamori, S | 1 |
| Boehden, GS; Marschalek, R; Restle, A; Stocking, C; Wiesmüller, L | 1 |
| Kitawaki, T; Nishikori, M; Ohno, H; Uchiyama, T; Ueda, C | 1 |
| Hosokawa, Y; Seto, M; Suzuki, H; Suzuki, Y; Takahashi, R | 1 |
| Forestier, E; Frost, BM; Gustafsson, G; Hellebostad, M; Jonsson, OG; Kanerva, J; Larsson, R; Lönnerholm, G; Nygren, P; Schmiegelow, K | 1 |
| Felix, CA; Libura, J; Richardson, C; Slater, DJ | 1 |
| Boehlke, I; Bokemeyer, C; Hartmann, JT; Kanz, L; Kollmannsberger, C; Kuczyk, M; Metzner, B; Schleicher, J; Schleucher, N; Wierecky, J | 1 |
| Adès, L; Blair, IA; Cassinat, B; Chomienne, C; Cross, NC; Felix, CA; Fenaux, P; Grimwade, D; Lafage-Pochitaloff, M; Mason, A; Mistry, AR; Osheroff, N; Parry, A; Peniket, AJ; Reiter, A; Segal, MR; Solomon, E; Walz, C; Whitmarsh, RJ; Wiemels, JL | 1 |
| Cabanillas, F; Cox, JD; Ha, CS; Lee, MS; McLaughlin, P; Mesina, OM; Rodriguez, MA; Romaguera, JE; Tucker, SL; Younes, A | 1 |
| Hayashi, Y; Kanazawa, T; Morikawa, A; Ogawa, C; Taketani, T; Taki, T | 1 |
| Döhner, H; Döhner, K; Eiwen, K; Fröhling, S; Schlenk, RF; Scholl, C | 1 |
| Imoto, I; Inazawa, J; Katsuki, Y; Mizutani, S; Nagasawa, M; Nakada, S; Yokoyama, T | 1 |
| Mochiduki, Y; Muramoto, S | 1 |
| Blennow, E; Ernberg, I; Fadeel, B; Henter, JI; Karpova, MB; Nordenskjöld, M; Schoumans, J; Smirnov, AF | 1 |
| Brichard, B; Chantrain, C; De Potter, P; Gala, JL; Sibille, C; Vermylen, C | 1 |
| Brandalise, SR; Matsuda, EI; Nowill, AE; Oliveira, SN; Rodrigues, PC; Viana, MB; Yunes, JA | 1 |
| Martin, PL; McLean, TW; White, MS | 1 |
| Alfaro, EM; Alonso, CN; Baro, C; Corral, Mdel P; Felice, MS; Gallego, MS; Rossi, J; Solé, F; Villa, O | 1 |
| Barjesteh van Waalwijk van Doorn-Khosrovani, S; Godschalk, RW; Janssen, J; Maas, LM; Nijhuis, JG; van Schooten, FJ | 1 |
| Fujishima, M; Fujishima, N; Hirokawa, M; Inomata, M; Kameoka, Y; Saitoh, H; Saitoh, K; Sawada, K; Takahashi, N; Yamanaka, Y; Yoshioka, T | 1 |
| Bogni, A; Cheng, C; Dolan, ME; Fan, Y; Hartford, C; Liu, W; Neale, G; Pounds, S; Pui, CH; Raimondi, SC; Relling, MV; Treviño, L; Yang, W | 1 |
| Afanasyeva, EA; Bahram, F; Guzhova, IV; Komarova, EY; Larsson, LG; Margulis, BA | 1 |
| Caracciolo, F; Focosi, D; Galimberti, S; Papineschi, F; Petrini, M | 1 |
| Abla, O; Dror, Y; Shago, M | 1 |
| Iarovaia, OV; Razin, SV; Rubtsov, MA; Terekhov, SM | 1 |
| Cheung, NK; Choi, JK; Felix, CA; Jhanwar, SC; Kolaris, CP; Osheroff, N; Robinson, BW | 1 |
| Basecke, J; Becker, A; Glass, B; Griesinger, F; Haase, D; Podleschny, M; Schmitz, N; Schwiers, I; Schwiers, R; Seiffert, E; Trumper, L | 1 |
| Barlogie, B; Cabanillas, F; Freireich, EJ; Keating, M | 1 |
| Brown, BW; Chao, NJ; Horning, SJ; Hoyle, C; Hu, WW; Kusnierz-Glaz, CR; Long, GD; Negrin, RS; Schriber, JR; Still, BJ | 1 |
| Anastasi, J; Hayashi, Y; McGavran, L; Nucifora, G; Roulston, D; Rowley, JD; Rudinsky, R; Tsuchida, M; Zeleznik-Le, N | 1 |
| Amadori, S; Avvisati, G; Cedrone, M; Cimino, G; Mancini, F; Mandelli, F; Moleti, ML; Testi, AM; Todisco, E | 1 |
| Aster, JC; Inhorn, RC; Roach, SA; Slapak, CA; Soiffer, R; Stone, RM; Tantravahi, R | 1 |
| Breeden, ES; Einhorn, LH; Loehrer, PJ; Nichols, CR; Williams, SD | 1 |
| Felix, CA; Hosler, MR; Lange, BJ; Masterson, M; Wilson, AE; Winick, NJ | 1 |
| Egeler, RM | 1 |
| Berger, R; Bernard, O; Derré, J; Flexor, M; Hillion, J; Jonveaux, P; Larsen, CJ; Le Coniat, M | 1 |
| Castel, V; Esquembre, C; Ferris, J; López-Andreu, JA; Verdeguer, A | 1 |
| Baruchel, A; Berger, R; Daniel, MT; Derré, J; Hillion, J; Le Coniat, M; Leblanc, T | 1 |
| Fujita, N; Goto, H; Inaba, T; Moriguchi, T; Seto, M; Shimazaki, C; Tatsumi, T; Ueda, R; Yamagata, N; Yamamoto, K | 1 |
| Ishizaki, T; Itoyama, T; Kuriyama, K; Nakamura, H; Sadamori, N; Soda, H; Tomonaga, M; Yamada, Y; Yoshida, Y | 1 |
| Corey, SJ; Gollin, SM; Locker, J; Oliveri, DR; Penchansky, L; Redner, RL; Shekhter-Levin, S | 1 |
| Iida, H; Iida, M; Kodera, Y; Minami, S; Seto, M; Sugihara, T; Suzuki, R; Taji, H; Ueda, R; Yamamoto, K | 1 |
| Barnett, MJ; Bredeson, CN; Dalal, BI; Horsman, DE; Phillips, GL; Ragaz, J | 1 |
| Hossfeld, DK; Shi, G; Weh, HJ | 1 |
| Egi, S; Horibe, K; Katayama, I; Kitabayashi, T; Matsushita, T; Miyajima, Y; Numata, S; Sekiguchi, N; Yanai, M | 1 |
| Amess, J; Bower, M; Evans, GA; Gibbons, B; Lister, TA; Parry, P; Young, BD | 1 |
| Bowman, WP; Croce, CM; Felix, CA; Lange, BJ; Negrini, M; Winick, NJ | 1 |
| Comelli, A; De Bernardi, B; Haupt, R; Rosanda, C; Sessarego, M | 1 |
| Ambra, R; Antonelli, A; Barbieri, C; Elli, R; Marcucci, L; Petrinelli, P | 1 |
| Broeker, PL; Pomykala, H; Rowley, JD; Super, HG; Tanabe, S; Thirman, MJ; Yonebayashi, Y; Zeleznik-Le, N | 1 |
| Deguchi, S; Fujita, M; Honda, K; Kikuchi, T; Miyata, A | 1 |
| Kearns, P; Majumdar, G; Partridge, F; Richardson, W; Wilcox, R | 1 |
| Mahendra, P; Marcus, RE; Nacheva, E; Richards, EM; Sinclair, P | 1 |
| Kakihara, T; Kataoka, S; Kishi, K; Okada, R; Tanaka, A; Uchiyama, M; Watanabe, A; Yamamoto, K | 1 |
| Ando, T; Ariyoshi, K; Hikiji, K; Kobayashi, M; Shinohara, K; Toyosawa, M | 1 |
| De Terlizzi, M; Fears, TR; Gadner, H; Haupt, R; Heise, A; Loiacono, G; Tucker, MA | 1 |
| Aplan, PD; Chervinsky, DS; Stanulla, M; Wang, J | 1 |
| Bayle, C; Carde, P; Macintyre, E; Nasr, F; Ribrag, V; Venuat, AM | 1 |
| Aplan, PD; Chervinsky, DS; Stanulla, M; Thandla, S; Wang, J | 1 |
| Horibe, K; Kudo, K; Naoe, T; Ohno, R; Yoshida, H | 1 |
| Fujita, M; Murata, M; Nagai, M; Ohmori, M; Takahara, J | 1 |
| Darroudi, F; Mosesso, P; Natarajan, AT; Palitti, F; van den Berg, M; Vermeulen, S | 1 |
| Advani, SH; Chougule, A; Gladstone, B; Kadam, PR; Kapoor, G | 1 |
| Ariyoshi, K; Kameda, N; Shinohara, K; Takeda, K | 1 |
| Fusaoka, T; Kataoka, A; Tunamoto, K; Wakazono, Y | 1 |
| Fuscoe, JC; Hanley, NM; Knapp, GW; Pui, CH; Relling, MV; Sandlund, JT; Setzer, RW | 1 |
| Brugières, L; Deley, MC; Delsol, G; Devalck, C; Hartmann, O; Leverger, G; Meguerian-Bedoyan, Z; Pacquement, H; Pondarré, C; Robert, A; Rodary, C; Terrier-Lacombe, MJ | 1 |
| Hotta, T; Imaizumi, S; Motoyama, T; Ogose, A; Takahashi, HE | 1 |
| Astori, C; Bernasconi, C; Bernasconi, P; Boni, M; Calatroni, S; Caresana, M; Cavigliano, PM; Malcovati, L | 1 |
| Chillón, C; García, JL; González, M; Gutiérrez, NC; Hernández, JM; Muntión, S | 1 |
| Buonaiuto, MR; De Renzo, A; Luciano, L; Notaro, R; Pane, F; Rotoli, B; Santoro, LF | 1 |
| Mollee, PN; Rodwell, R; Taylor, D; Taylor, KM; Williams, B | 1 |
| Ikeda, K; Ikeda, T; Kawakami, K; Sasaki, K; Takahara, J | 1 |
| Barnett, M; Connors, JM; Gascoyne, RD; Horsman, D; Klasa, R; Lesack, D; Macpherson, N | 1 |
| Felgenhauer, J; Hawkins, D; Radich, J; Thomson, B | 1 |
| Fuscoe, JC; Hagmar, L; Hellgren, D; Lambert, B; Meydan, D; Nilsson, T; Törnblom, M | 1 |
| Andoh, T | 1 |
| Engel, R; Gump, JL; Sullivan, DM; Valkov, NI | 1 |
| Addya, K; Cheung, NK; Felix, CA; Jones, DH; Kushner, BH; Lange, BJ; Leonard, DG; Megonigal, MD; Nowell, PC; Rappaport, EF; Williams, TM; Wilson, RB | 1 |
| Arai, Y; Iwata, M; Kawano, A; Nakao, K; Nishino, M; Ohki, M; Takeuchi, K | 1 |
| Camitta, B; Carroll, AJ; Chang, M; Gresik, MV; Raimondi, SC; Ravindranath, Y; Steuber, CP; Weinstein, H | 1 |
| Eguchi, M; Eguchi-Ishimae, M; Ishii, E; Kamada, N; Miyazaki, S; Mizutani, S; Ueda, K | 1 |
| Blair, IA; Burden, DA; Felix, CA; Lovett, BD; Megonigal, MD; Osheroff, N; Pang, S; Pommier, YG; Rappaport, EF; Rebbeck, TR; Strumberg, D | 1 |
| Bishop, JB; Generoso, WM; Hozier, J; Lowe, X; Marchetti, F; Wyrobek, AJ | 1 |
| Bernasconi, P; Boni, M; Castoldi, GL; Ciolli, S; Clavio, M; Cox, MC; Cuneo, A; Del Poeta, G; Dini, D; Falzetti, D; Fanin, R; Gobbi, M; Isidori, A; Leoni, F; Liso, V; Malagola, M; Mandelli, F; Martinelli, G; Mecucci, C; Petti, MC; Piccaluga, PP; Rondelli, R; Russo, D; Sessarego, M; Specchia, G; Testoni, N; Torelli, G; Tura, S; Visani, G | 1 |
| Blair, IA; Felix, CA; Lo Nigro, L; Lovett, BD; Megonigal, MD; Nowell, PC; Osheroff, N; Rappaport, EF; Williams, WR; Zheng, N | 1 |
| Eguchi, M; Hayashi, Y; Hibi, S; Hongo, T; Imaizumi, M; Ishii, E; Isoyama, K; Kamada, N; Kawasaki, H; Kinukawa, N; Kosaka, Y; Mizutani, S; Nishimura, S; Oda, M; Oda, T; Okamura, T; Okawa, H; Tsukimoto, I | 1 |
| Hara, T; Kanemura, N; Moriwaki, H; Naito, T; Sawada, M; Tsurumi, H; Yamada, T | 1 |
| Fukuda, N; Muraki, K; Ota, I; Shimohakamada, Y; Shinohara, K | 1 |
| Case, D; Damon, LE; Linker, CA; Navarro, WA; Ries, CA; Wolf, JL | 1 |
| Brito, G; Fernandez, T; Klumb, C; Land, MG; Maradei, S; Otero, L; Pombo-de-Oliveira, MS; Silva, ML; Veith, M | 1 |
| Mitchell, DC; Win, N | 1 |
| Cerrillo, M; Cervantes, G; Gagnière, M; Gorodezky, G; Mohar, A; Neyra, O; Osornio, A; Reynoso, E; Salles, MT; Taja, L | 1 |
| Elliott, S; Marlton, P; Meagher, D; Rodwell, R; Taylor, D; Taylor, K; Timms, P; White, S; Wiley, J; Wright, S | 1 |
| Challis, J; Farag, S; Garson, OM; White, J | 1 |
| Kaneko, Y; Kawai, S; Kondo, M; Mimaya, J; Tonouchi, T; Toyoda, Y; Ueda, R | 1 |
| Akiyama, Y; Kubota, M; Mikawa, H; Tabata, Y; Yoshigi, M | 1 |
12 review(s) available for etoposide and Chromosomal Translocation
| Article | Year |
|---|---|
Hitting back at lymphoma: How do modern diagnostics identify high-risk diffuse large B-cell lymphoma subsets and alter treatment?
Topics: Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Biphenyl Compounds; Cyclophosphamide; Doxorubicin; Enhancer of Zeste Homolog 2 Protein; Etoposide; Gene Expression Profiling; Humans; Immunotherapy, Adoptive; Lymphoma, Large B-Cell, Diffuse; Mediastinal Neoplasms; Molecular Diagnostic Techniques; Morpholines; Mutation; Prednisone; Programmed Cell Death 1 Receptor; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-bcl-6; Proto-Oncogene Proteins c-myc; Pyridones; Receptors, Chimeric Antigen; Risk; Rituximab; Translocation, Genetic; Vincristine | 2019 |
Double-hit and triple-hit lymphomas arising from follicular lymphoma following acquisition of MYC: report of two cases and literature review.
Topics: Adult; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Cell Transformation, Neoplastic; Cisplatin; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Humans; Lymphoma, B-Cell; Lymphoma, Follicular; Methylprednisolone; Middle Aged; Prednisone; Proto-Oncogene Proteins c-myc; Radiotherapy; Rituximab; Translocation, Genetic; Treatment Outcome; Vincristine; Whole-Body Irradiation | 2013 |
A role for epigenetics in the formation of chromosome translocations in acute leukemia.
Topics: Chromatin Assembly and Disassembly; Daunorubicin; DNA Breaks, Double-Stranded; Epigenesis, Genetic; Etoposide; Histone-Lysine N-Methyltransferase; Humans; Leukemia, Myeloid, Acute; Myeloid-Lymphoid Leukemia Protein; Translocation, Genetic | 2015 |
Paraspinal synovial sarcoma as an unusual postradiation complication in pediatric abdominal neuroblastoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 18; Chromosomes, Human, X; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dacarbazine; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Infant; Lumbar Vertebrae; Mechlorethamine; Muscle Neoplasms; Neoplasms, Radiation-Induced; Neoplasms, Second Primary; Neuroblastoma; Oncogene Proteins, Fusion; Remission Induction; Retroperitoneal Neoplasms; Sarcoma, Synovial; Spinal Stenosis; Translocation, Genetic; Vincristine | 2008 |
Anaplastic large cell lymphoma, ALK-positive.
Topics: Anaplastic Lymphoma Kinase; Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Leucovorin; Lymphoma, Large-Cell, Anaplastic; Methotrexate; Prednisolone; Prednisone; Receptor Protein-Tyrosine Kinases; Stem Cell Transplantation; T-Lymphocytes; Translocation, Genetic; Vincristine | 2012 |
Long-term propylthiouracil use and acute myeloid leukemia: a case report and review of the literature.
Topics: Adult; Antimetabolites; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 2; Chromosomes, Human, Pair 21; Cytarabine; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Iodide Peroxidase; Leukemia, Myeloid, Acute; Peroxidase; Propylthiouracil; Remission Induction; Time Factors; Translocation, Genetic; Transplantation, Homologous | 2008 |
The hematologic malignancies. Leukemia, lymphoma, and myeloma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Interferons; Leukemia; Lymphoma; Mechlorethamine; Multiple Myeloma; Prednisone; Procarbazine; Prognosis; Translocation, Genetic; Vincristine | 1984 |
Therapy-related acute leukemia associated with t(11q23) after primary acute myeloid leukemia with t(8;21): a report of two cases.
Topics: Anemia, Refractory, with Excess of Blasts; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cell Lineage; Child; Child, Preschool; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Enzyme Inhibitors; Etoposide; Fatal Outcome; Female; Humans; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Mitoxantrone; Neoplasms, Second Primary; Oncogenes; Topoisomerase II Inhibitors; Translocation, Genetic | 1995 |
A syndrome of lymphoblastic lymphoma, eosinophilia, and myeloid hyperplasia/malignancy associated with t(8;13)(p11;q11): description of a distinctive clinicopathologic entity.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Carboplatin; Chromosomes, Human, Pair 13; Chromosomes, Human, Pair 8; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Eosinophilia; Etoposide; Fatal Outcome; Female; Humans; Hydroxyurea; Hyperplasia; Ifosfamide; Leukemia, Myeloid; Lymph Nodes; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Pregnancy; Pregnancy Complications, Neoplastic; Remission Induction; Syndrome; Translocation, Genetic; Vincristine | 1995 |
Acute myeloid leukaemia with t(9;11)(p22;q23) in a patient treated for adult T cell leukaemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 9; Cyclophosphamide; Etoposide; Humans; Karyotyping; Leukemia, Myeloid, Acute; Leukemia, T-Cell; Male; Neoplasms, Second Primary; Translocation, Genetic | 1994 |
The prognostic value of cytogenetics is reinforced by the kind of induction/consolidation therapy in influencing the outcome of acute myeloid leukemia--analysis of 848 patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosome Deletion; Chromosome Inversion; Chromosomes, Human; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Hepatomegaly; Humans; Idarubicin; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Prognosis; Remission Induction; Retrospective Studies; Splenomegaly; Survival Analysis; Translocation, Genetic; Treatment Outcome | 2001 |
Therapy-related myelodysplastic syndrome in a case of cutaneous adult T-cell lymphoma.
Topics: Acute Disease; Aged; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chromosome Aberrations; Combined Modality Therapy; Cyclophosphamide; Disease Progression; Doxorubicin; Etoposide; Fatal Outcome; HTLV-I Infections; Human T-lymphotropic virus 1; Humans; Japan; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myeloid; Lymphoma, T-Cell, Cutaneous; Male; Nitrosourea Compounds; Prednisolone; Proviruses; Radiotherapy; Remission Induction; Translocation, Genetic; Vincristine | 2002 |
7 trial(s) available for etoposide and Chromosomal Translocation
| Article | Year |
|---|---|
Clinical Impact of the Cell-of-Origin Classification and the MYC/ BCL2 Dual Expresser Status in Diffuse Large B-Cell Lymphoma Treated Within Prospective Clinical Trials of the German High-Grade Non-Hodgkin's Lymphoma Study Group.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Etoposide; Female; Germany; Germinal Center; Humans; Lymphoma, Large B-Cell, Diffuse; Male; Middle Aged; Prednisone; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-bcl-6; Proto-Oncogene Proteins c-myc; Rituximab; Survival Rate; Translocation, Genetic; Vincristine; Young Adult | 2017 |
Phase 1 study of lenalidomide plus dose-adjusted EPOCH-R in patients with aggressive B-cell lymphomas with deregulated MYC and BCL2.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Feasibility Studies; Female; Humans; Lenalidomide; Lymphoma, Large B-Cell, Diffuse; Maintenance Chemotherapy; Male; Maximum Tolerated Dose; Middle Aged; Prednisone; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Rituximab; Translocation, Genetic; Treatment Outcome; Vincristine | 2019 |
A prospective randomized study to compare the molecular response rates between central lymphatic irradiation and intensive alternating triple chemotherapy in the treatment of stage I-III follicular lymphoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Etoposide; Genes, bcl-2; Humans; Lymphoma, Follicular; Methylprednisolone; Middle Aged; Mitoxantrone; Polymerase Chain Reaction; Prednisone; Procarbazine; Prospective Studies; Translocation, Genetic; Vincristine | 2005 |
Therapy-associated genetic aberrations in patients treated for non-Hodgkin lymphoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Middle Aged; Prednisolone; Prognosis; Prospective Studies; Reverse Transcriptase Polymerase Chain Reaction; Translocation, Genetic; Vincristine | 2008 |
Transplantation of enriched and purged peripheral blood progenitor cells from a single apheresis product in patients with non-Hodgkin's lymphoma.
Topics: Adolescent; Adult; Antigens, CD; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Blood Component Removal; Bone Marrow Purging; Carmustine; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 18; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Etoposide; Female; Graft Survival; Granulocyte Colony-Stimulating Factor; Hematopoiesis; Hematopoietic Stem Cell Transplantation; Humans; Lymphoma, Non-Hodgkin; Male; Middle Aged; Neoplastic Stem Cells; Polymerase Chain Reaction; Remission Induction; Salvage Therapy; Translocation, Genetic; Treatment Outcome; Whole-Body Irradiation | 1995 |
CD30(+) anaplastic large-cell lymphoma in children: analysis of 82 patients enrolled in two consecutive studies of the French Society of Pediatric Oncology.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bleomycin; Child; Chromosomes, Human, Pair 2; Chromosomes, Human, Pair 5; Cyclophosphamide; Doxorubicin; Etoposide; Follow-Up Studies; France; Humans; Immunophenotyping; Lymphoma, Large-Cell, Anaplastic; Methotrexate; Prednisone; Prognosis; Protein-Tyrosine Kinases; Remission Induction; Retrospective Studies; Risk Factors; Survival Analysis; Survival Rate; Translocation, Genetic; Treatment Outcome; Vinblastine; Vincristine | 1998 |
Superior outcome of infant acute myeloid leukemia with intensive chemotherapy: results of the Japan Infant Leukemia Study Group.
Topics: Aclarubicin; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 11; Cytarabine; Disease-Free Survival; DNA-Binding Proteins; Doxorubicin; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Histone-Lysine N-Methyltransferase; Humans; Immunophenotyping; Infant; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Myeloid-Lymphoid Leukemia Protein; Prognosis; Proto-Oncogenes; Remission Induction; Survival Rate; Transcription Factors; Translocation, Genetic; Treatment Outcome; Vincristine | 2001 |
128 other study(ies) available for etoposide and Chromosomal Translocation
| Article | Year |
|---|---|
Nucleolar translocation of human DNA topoisomerase II by ATP depletion and its disruption by the RNA polymerase I inhibitor BMH-21.
Topics: Adenosine Triphosphate; Cell Nucleolus; DNA Topoisomerases, Type II; Enzyme Inhibitors; Etoposide; HeLa Cells; Heterocyclic Compounds, 4 or More Rings; Humans; Poly-ADP-Ribose Binding Proteins; RNA Polymerase I; Topoisomerase II Inhibitors; Translocation, Genetic | 2021 |
Recurrent Translocations in Topoisomerase Inhibitor-Related Leukemia Are Determined by the Features of DNA Breaks Rather Than by the Proximity of the Translocating Genes.
Topics: DNA; DNA Breaks, Double-Stranded; Etoposide; Humans; In Situ Hybridization, Fluorescence; Leukemia, Myeloid, Acute; Topoisomerase II Inhibitors; Translocation, Genetic | 2022 |
Epstein-Barr virus-positive diffuse large B cell lymphoma, not otherwise specified, carrying a t(19;22)(q13;q11) translocation.
Topics: Abnormal Karyotype; Aged; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Chromosomes, Human, Pair 19; Chromosomes, Human, Pair 22; Cisplatin; Cyclophosphamide; Cytarabine; Doxorubicin; Epstein-Barr Virus Infections; Etoposide; Humans; Lymphoma, Large B-Cell, Diffuse; Male; Methylprednisolone; Prednisone; Rituximab; RNA, Neoplasm; RNA, Viral; Translocation, Genetic; Vincristine | 2020 |
Bioflavonoids cause DNA double-strand breaks and chromosomal translocations through topoisomerase II-dependent and -independent mechanisms.
Topics: Animals; Cell Line; Chromosome Breakpoints; Chromosomes, Mammalian; Dexrazoxane; DNA; DNA Breaks, Double-Stranded; DNA Repair; DNA Topoisomerases, Type II; Etoposide; Flavonoids; Genistein; Histones; Kaempferols; Luteolin; Mice; Mouse Embryonic Stem Cells; Quercetin; Topoisomerase II Inhibitors; Translocation, Genetic | 2020 |
Histiocytic sarcoma progressing from follicular lymphoma and mimicking acquired hemophagocytic lymphohistiocytosis.
Topics: Antigens, CD; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Marrow; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 18; Cyclophosphamide; Dexamethasone; Diagnosis, Differential; Disease Progression; Doxorubicin; Etoposide; Female; Histiocytic Sarcoma; Humans; Lymph Nodes; Lymphohistiocytosis, Hemophagocytic; Lymphoma, Follicular; Middle Aged; Prednisolone; Rituximab; Translocation, Genetic; Vincristine | 2020 |
Therapy-related Acute Myeloid Leukemia after the Long-term Administration of Low-dose Etoposide for Chronic-type Adult T-cell Leukemia-lymphoma: A Case Report and Literature Review.
Topics: Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myeloid, Acute; Middle Aged; Translocation, Genetic | 2017 |
MiR-130a is aberrantly overexpressed in adult acute myeloid leukemia with t(8;21) and its suppression induces AML cell death.
Topics: Adult; Apoptosis; Cell Line, Tumor; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Core Binding Factor Alpha 2 Subunit; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; MicroRNAs; Oncogene Proteins, Fusion; RUNX1 Translocation Partner 1 Protein; Translocation, Genetic | 2018 |
Unexpected favorable outcome in a patient with high grade B-cell lymphoma with abnormalities of MYC, BCL6 and BCL2 loci.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chromosome Inversion; Chromosomes, Human, Pair 18; Chromosomes, Human, Pair 3; Cyclophosphamide; Doxorubicin; Etoposide; Female; Gene Expression Profiling; Gene Order; Genes, myc; Humans; In Situ Hybridization, Fluorescence; Lymphoma, B-Cell; MDS1 and EVI1 Complex Locus Protein; Middle Aged; Neoplasm Grading; Prednisone; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-bcl-6; Proto-Oncogene Proteins c-myc; Remission Induction; Sequence Analysis, RNA; Translocation, Genetic; Treatment Outcome; Vincristine | 2018 |
Distinct roles of ATM and ATR in the regulation of ARP8 phosphorylation to prevent chromosome translocations.
Topics: Ataxia Telangiectasia Mutated Proteins; ATPases Associated with Diverse Cellular Activities; Cell Line; DNA Helicases; DNA Repair; DNA-Binding Proteins; Etoposide; Humans; Microfilament Proteins; Phosphorylation; Protein Processing, Post-Translational; Rad51 Recombinase; Translocation, Genetic | 2018 |
Diffuse large B cell lymphoma with chromosomal translocation t(14;19)(q32;q13) occurring in IgG4-related disease.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 19; Dexamethasone; Etoposide; Female; Humans; Ifosfamide; Immunoglobulin G4-Related Disease; Lymphoma, Large B-Cell, Diffuse; Positron-Emission Tomography; Rituximab; Salvage Therapy; Translocation, Genetic | 2019 |
Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity.
Topics: Chromosome Breakage; Chromosomes; DNA; DNA Breaks, Double-Stranded; DNA Repair; DNA Topoisomerases, Type II; DNA-Binding Proteins; Etoposide; Gene Conversion; HCT116 Cells; Humans; Kinetics; Multiprotein Complexes; Poly-ADP-Ribose Binding Proteins; Topoisomerase II Inhibitors; Torsion, Mechanical; Transcription, Genetic; Translocation, Genetic | 2019 |
The broken MLL gene is frequently located outside the inherent chromosome territory in human lymphoid cells treated with DNA topoisomerase II poison etoposide.
Topics: Chromosomes, Human, Pair 11; DNA Cleavage; DNA Topoisomerases, Type II; Etoposide; Histone-Lysine N-Methyltransferase; Humans; Imaging, Three-Dimensional; In Situ Hybridization, Fluorescence; Jurkat Cells; Lymphocytes; Microscopy, Confocal; Models, Molecular; Myeloid-Lymphoid Leukemia Protein; Translocation, Genetic | 2013 |
The role of topoisomerase II beta on breakage and proximity of RUNX1 to partner alleles RUNX1T1 and EVI1.
Topics: Antineoplastic Agents; Base Sequence; Cell Line, Tumor; Chromatin; Chromosome Breakage; Core Binding Factor Alpha 2 Subunit; DNA Breaks, Double-Stranded; DNA Topoisomerases, Type II; DNA-Binding Proteins; Etoposide; Humans; MDS1 and EVI1 Complex Locus Protein; Molecular Sequence Data; Poly-ADP-Ribose Binding Proteins; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogene Proteins; Proto-Oncogenes; RUNX1 Translocation Partner 1 Protein; Transcription Factors; Translocation, Genetic | 2014 |
NUT midline carcinoma: an aggressive intrathoracic neoplasm.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Etoposide; Gene Rearrangement; Humans; Ifosfamide; In Situ Hybridization, Fluorescence; Male; Nuclear Proteins; Oncogene Proteins, Fusion; Prognosis; Thoracic Neoplasms; Translocation, Genetic | 2013 |
Leukemic phase of ALK(+) anaplastic large-cell lymphoma, small-cell variant: clinicopathologic pitfalls of a rare entity.
Topics: Anaplastic Lymphoma Kinase; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Marrow; Cyclophosphamide; Doxorubicin; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunohistochemistry; Immunophenotyping; In Situ Hybridization, Fluorescence; Karyotype; Lymphocytes; Lymphoma, Large-Cell, Anaplastic; Prednisone; Receptor Protein-Tyrosine Kinases; Translocation, Genetic; Transplantation, Homologous; Treatment Outcome; Vincristine; Young Adult | 2014 |
How I treat Burkitt lymphoma in adults.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Humans; Ifosfamide; Male; Methotrexate; Nasopharyngeal Neoplasms; Prednisone; Prognosis; Translocation, Genetic; Vincristine | 2014 |
Minimal residual disease monitored after induction therapy by RQ-PCR can contribute to tailor treatment of patients with t(8;21) RUNX1-RUNX1T1 rearrangement.
Topics: Antineoplastic Agents; Biomarkers, Tumor; Child; Child, Preschool; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Core Binding Factor Alpha 2 Subunit; Cytarabine; Drug Monitoring; Etoposide; Female; Humans; Idarubicin; Induction Chemotherapy; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Mutation; Neoplasm, Residual; Proto-Oncogene Proteins; RUNX1 Translocation Partner 1 Protein; Survival Analysis; Transcription Factors; Translocation, Genetic | 2015 |
[Successful treatment with dose-adjusted EPOCH-R for triple-hit lymphoma having BCL2, BCL6 and MYC translocations].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytogenetic Analysis; DNA-Binding Proteins; Doxorubicin; Etoposide; Humans; Lymphoma, B-Cell; Male; Prednisone; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-bcl-6; Proto-Oncogene Proteins c-myc; Translocation, Genetic; Vincristine | 2015 |
Clinical Impact of Additional Cytogenetic Aberrations, cKIT and RAS Mutations, and Treatment Elements in Pediatric t(8;21)-AML: Results From an International Retrospective Study by the International Berlin-Frankfurt-Münster Study Group.
Topics: Adolescent; Anthracyclines; Antineoplastic Agents; Child; Child, Preschool; Chromosome Aberrations; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Disease-Free Survival; Etoposide; Female; Germany; Hematopoietic Stem Cell Transplantation; Humans; Incidence; Induction Chemotherapy; International Cooperation; Kaplan-Meier Estimate; Karyotype; Leukemia, Myeloid, Acute; Male; Molecular Targeted Therapy; Mutation; Predictive Value of Tests; Proto-Oncogene Proteins c-kit; ras Proteins; Retrospective Studies; Translocation, Genetic; Transplantation, Homologous; Treatment Outcome | 2015 |
NUT midline carcinoma of the lung, a rare form of lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chromosomes, Human, Pair 15; Cisplatin; Etoposide; Fatal Outcome; Humans; Lung Neoplasms; Male; Neoplasm Proteins; Nuclear Proteins; Oncogene Proteins; Palliative Care; Pneumonectomy; Positron-Emission Tomography; Proteins; Tomography, X-Ray Computed; Translocation, Genetic; Young Adult | 2016 |
Extremely slow methotrexate elimination in a patient with t(9;22) positive acute lymphoblastic leukemia treated with imatinib.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Chromosomes, Human, Pair 22; Chromosomes, Human, Pair 9; Cytarabine; Drug Interactions; Edema; Etoposide; Female; Humans; Imatinib Mesylate; Leucovorin; Methotrexate; Middle Aged; Piperazines; Pleural Effusion, Malignant; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Pyrimidines; Sodium Potassium Chloride Symporter Inhibitors; Translocation, Genetic | 2008 |
BCR/ABL induces chromosomal instability after genotoxic stress and alters the cell death threshold.
Topics: Cell Death; Cell Survival; Chromosomal Instability; DNA Breaks, Double-Stranded; DNA Damage; DNA Repair; Etoposide; Fusion Proteins, bcr-abl; Hematopoietic Stem Cells; Humans; Translocation, Genetic; Tumor Cells, Cultured | 2009 |
Cytogenetic and molecular analysis of MLL rearrangements in acute lymphoblastic leukaemia survivors.
Topics: Adolescent; Adult; Base Sequence; Case-Control Studies; Child; Child, Preschool; Chromosomes, Human, Pair 11; Cytogenetic Analysis; Etoposide; Gene Rearrangement; Humans; Molecular Sequence Data; Myeloid-Lymphoid Leukemia Protein; Polymerase Chain Reaction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Survivors; Teniposide; Translocation, Genetic | 2009 |
Molecular targeting of MLL-rearranged leukemia cell lines with the synthetic peptide PFWT synergistically enhances the cytotoxic effect of established chemotherapeutic agents.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Cycle; Cell Proliferation; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 4; Chromosomes, Human, Pair 9; Colony-Forming Units Assay; Cytarabine; DNA-Binding Proteins; Drug Synergism; Etoposide; Gene Rearrangement; Histone-Lysine N-Methyltransferase; Humans; Leukemia; Myeloid-Lymphoid Leukemia Protein; Necrosis; Nuclear Proteins; Peptide Fragments; Transcriptional Elongation Factors; Translocation, Genetic; Tumor Cells, Cultured | 2009 |
Loss of p53 and MCT-1 overexpression synergistically promote chromosome instability and tumorigenicity.
Topics: Aneuploidy; Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Cell Adhesion; Cell Cycle Proteins; Cell Movement; Cell Proliferation; Chromosomal Instability; Cytogenetic Analysis; Drug Synergism; Etoposide; Female; Flow Cytometry; Humans; Immunoblotting; Immunoenzyme Techniques; Lung Neoplasms; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Mutagens; Oncogene Proteins; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Translocation, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2009 |
Desmoplastic small round cell tumor in children: a new therapeutic approach.
Topics: Abdominal Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carboplatin; Child; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 22; Combined Modality Therapy; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Liver Neoplasms; Lung Neoplasms; Male; Neoadjuvant Therapy; Oncogene Proteins, Fusion; Pelvic Neoplasms; Radiotherapy, Adjuvant; Sarcoma, Small Cell; Splenic Neoplasms; Translocation, Genetic; Transplantation, Autologous; Vincristine | 2009 |
Jumping translocation involving 1q21 during long-term complete remission of acute myeloid leukemia.
Topics: Adult; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 1; Cytarabine; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Recurrence; Time Factors; Translocation, Genetic | 2010 |
Biphenotypic hematologic malignancy: a case report of the 8p11 myeloproliferative syndrome in a child.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Chromosomes, Human, Pair 13; Chromosomes, Human, Pair 8; Cyclophosphamide; Dexamethasone; Doxorubicin; Etoposide; Humans; Male; Myeloproliferative Disorders; Phenotype; Precancerous Conditions; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Syndrome; Translocation, Genetic; Vincristine | 2010 |
ATM modulates the loading of recombination proteins onto a chromosomal translocation breakpoint hotspot.
Topics: Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Chromosomes, Human, Pair 11; DNA-Binding Proteins; Etoposide; Histone-Lysine N-Methyltransferase; Humans; Myeloid-Lymphoid Leukemia Protein; Protein Binding; Protein Serine-Threonine Kinases; Rad51 Recombinase; Recombination, Genetic; Replication Protein A; Translocation, Genetic; Tumor Suppressor Proteins | 2010 |
Acute promyelocytic leukemia following chemotherapy for EBV-associated hemophagocytic lymphohistiocytosis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cyclosporine; Dexamethasone; Epstein-Barr Virus Infections; Etoposide; Herpesvirus 4, Human; Humans; In Situ Hybridization, Fluorescence; Infant; Karyotyping; Leukemia, Promyelocytic, Acute; Lymphatic Diseases; Lymphohistiocytosis, Hemophagocytic; Male; Oncogene Proteins, Fusion; Translocation, Genetic | 2011 |
Backtracking to birth of the NUP98-HOXD13 gene fusion in an infant acute myeloid leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Base Sequence; Bone Marrow Cells; Chromosome Banding; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 2; Cytarabine; Etoposide; Humans; Idarubicin; Infant; Infant, Newborn; Leukemia, Myelomonocytic, Acute; Male; Molecular Sequence Data; Neonatal Screening; Oncogene Proteins, Fusion; Remission Induction; Reverse Transcriptase Polymerase Chain Reaction; Translocation, Genetic | 2011 |
Bcl-2 is a better therapeutic target than c-Myc, but attacking both could be a more effective treatment strategy for B-cell lymphoma with concurrent Bcl-2 and c-Myc overexpression.
Topics: Aniline Compounds; Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Cell Survival; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 18; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Lymphoma, Large B-Cell, Diffuse; MicroRNAs; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Reverse Transcriptase Polymerase Chain Reaction; Spectral Karyotyping; Sulfonamides; Thiazoles; Translocation, Genetic | 2011 |
Case report of a poorly differentiated uterine tumour with t(10;17) translocation and neuroectodermal phenotype.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cell Differentiation; Chromosomes, Human, Pair 10; Chromosomes, Human, Pair 17; Cisplatin; Etoposide; Female; Humans; Neuroectodermal Tumors; Phenotype; Sarcoma, Endometrial Stromal; Translocation, Genetic; Uterine Neoplasms | 2011 |
Unexpected pancytopenia following treatment of acute lymphoblastic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Chromosomes, Human, Pair 6; Chromosomes, Human, Pair 9; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Daunorubicin; Erythropoiesis; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Maintenance Chemotherapy; Mercaptopurine; Methotrexate; Middle Aged; Neoplasms, Second Primary; Oncogene Proteins, Fusion; Pancytopenia; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Translocation, Genetic; Vincristine | 2012 |
Model for MLL translocations in therapy-related leukemia involving topoisomerase IIβ-mediated DNA strand breaks and gene proximity.
Topics: Chromatin Immunoprecipitation; DNA Breaks, Double-Stranded; DNA Topoisomerases, Type II; DNA-Binding Proteins; Etoposide; Fluorescence; Humans; In Situ Hybridization, Fluorescence; Leukemia, Myeloid, Acute; Micronucleus Tests; Models, Biological; Myeloid-Lymphoid Leukemia Protein; Neoplasms, Second Primary; Translocation, Genetic | 2012 |
[Genetic prognostic factors in childhood acute myeloid leukemia].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Chromosome Aberrations; Chromosome Deletion; Chromosome Disorders; Chromosomes, Human, Pair 7; Cytarabine; DNA Mutational Analysis; Etoposide; Female; fms-Like Tyrosine Kinase 3; Genes, Wilms Tumor; Genetic Markers; Humans; Idarubicin; Infant; Kaplan-Meier Estimate; Karyotyping; Leukemia, Myeloid, Acute; Male; Myelodysplastic Syndromes; Nuclear Proteins; Nucleophosmin; Prognosis; Survival Rate; Translocation, Genetic | 2012 |
Do transcription factories and TOP2B provide a recipe for chromosome translocations in therapy-related leukemia?
Topics: Anthracyclines; DNA Breaks, Double-Stranded; DNA Topoisomerases, Type II; DNA-Binding Proteins; Epirubicin; Etoposide; Humans; Leukemia; Mitoxantrone; Models, Genetic; Neoplasms, Second Primary; Poly-ADP-Ribose Binding Proteins; Translocation, Genetic | 2012 |
[Successful treatment with G-CSF and continuous infusion of low-dose cytarabine and etoposide for therapy-related acute myeloid leukemia developed during chemotherapy for malignant lymphoma].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 9; Cytarabine; Etoposide; Granulocyte Colony-Stimulating Factor; Humans; Infusions, Intravenous; Leukemia, Myelomonocytic, Acute; Lymphoma, Non-Hodgkin; Male; Neoplasms, Second Primary; Remission Induction; Translocation, Genetic | 2002 |
Cellular drug resistance in childhood acute myeloid leukemia is related to chromosomal abnormalities.
Topics: Acute Disease; Adolescent; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Chromosome Aberrations; Chromosome Inversion; Chromosomes, Human; Cladribine; Cytarabine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Infant; Leukemia, Myeloid; Male; Neoplastic Stem Cells; Recurrence; Remission Induction; Tetrazolium Salts; Thiazoles; Translocation, Genetic; Trisomy | 2002 |
Blast crisis of chronic myeloid leukemia: diagnosis prompted by T(8;9).
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Bone Marrow Transplantation; Child, Preschool; Chromosomes, Human, Pair 8; Chromosomes, Human, Pair 9; Combined Modality Therapy; Cytarabine; Daunorubicin; Ethmoid Sinus; Etoposide; Fusion Proteins, bcr-abl; Humans; Karyotyping; Leukemia, Myeloid, Accelerated Phase; Male; Meninges; Mitoxantrone; Remission Induction; Sacrococcygeal Region; Sarcoma, Myeloid; Thioguanine; Translocation, Genetic | 2002 |
NP-1, a rabbit alpha-defensin, prevents the entry and intercellular spread of herpes simplex virus type 2.
Topics: Acyclovir; alpha-Defensins; Amino Acid Sequence; Animals; Antiviral Agents; Chlorocebus aethiops; Etoposide; Herpes Genitalis; Herpesvirus 2, Human; Translocation, Genetic; Vero Cells | 2003 |
[De novo acute lymphocytic leukemia with t(14;18) complicated by tumor lysis syndrome].
Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 18; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Etoposide; Fatal Outcome; Humans; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Rituximab; Translocation, Genetic; Treatment Failure; Tumor Lysis Syndrome; Vincristine | 2003 |
Telomerase activity, apoptosis and cell cycle progression in ataxia telangiectasia lymphocytes expressing TCL1.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Ataxia Telangiectasia; Cell Cycle; Cell Transformation, Neoplastic; Chromosomes, Human, Pair 14; Clone Cells; DNA-Binding Proteins; Etoposide; Gene Expression Regulation; Humans; Preleukemia; Proto-Oncogene Proteins; T-Lymphocytes; Telomerase; Telomere; Transcription Factors; Translocation, Genetic | 2003 |
MLL/AF-1p fusion in therapy-related early pre-B acute lymphoblastic leukemia with t(1;11)(p32;q23) translocation developing in the relapse phase of acute promyelocytic leukemia.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 11; Cytarabine; Daunorubicin; Enzyme Inhibitors; Etoposide; Fatal Outcome; Humans; Idarubicin; In Situ Hybridization, Fluorescence; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Mitoxantrone; Myeloid-Lymphoid Leukemia Protein; Neoplasm Proteins; Neoplasms, Second Primary; Oncogene Proteins, Fusion; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Topoisomerase II Inhibitors; Translocation, Genetic; Tretinoin | 2003 |
Recombination at chromosomal sequences involved in leukaemogenic rearrangements is differentially regulated by p53.
Topics: Animals; Baculoviridae; Cell Line; Chromosomes; Cloning, Molecular; COS Cells; DNA; Down-Regulation; Enzyme Inhibitors; Etoposide; Gene Deletion; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; Leukemia; Models, Genetic; Mutation; Phenotype; Receptors, Retinoic Acid; Recombination, Genetic; Retinoic Acid Receptor alpha; Time Factors; Translocation, Genetic; Tumor Suppressor Protein p53 | 2004 |
Coexistent rearrangements of c-MYC, BCL2, and BCL6 genes in a diffuse large B-cell lymphoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chromosomes, Human; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 18; Chromosomes, Human, Pair 22; Chromosomes, Human, Pair 3; Chromosomes, Human, Pair 8; Combined Modality Therapy; Dexamethasone; DNA-Binding Proteins; Etoposide; Genes, bcl-2; Genes, myc; Humans; Ifosfamide; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Male; Middle Aged; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-6; Proto-Oncogenes; Radiotherapy, Adjuvant; Remission Induction; Transcription Factors; Translocation, Genetic | 2004 |
Antiapoptotic function of apoptosis inhibitor 2-MALT1 fusion protein involved in t(11;18)(q21;q21) mucosa-associated lymphoid tissue lymphoma.
Topics: Amino Acid Sequence; Apoptosis; Apoptosis Regulatory Proteins; Carrier Proteins; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 18; Electrophoresis, Polyacrylamide Gel; Etoposide; Humans; Intracellular Signaling Peptides and Proteins; Lymphoma, B-Cell, Marginal Zone; Mitochondrial Proteins; Molecular Sequence Data; Oncogene Proteins, Fusion; Precipitin Tests; Protein Binding; Spectrometry, Mass, Electrospray Ionization; Translocation, Genetic; Ultraviolet Rays | 2004 |
Translocation t(12;21) is related to in vitro cellular drug sensitivity to doxorubicin and etoposide in childhood acute lymphoblastic leukemia.
Topics: Adolescent; Cell Line, Tumor; Child; Child, Preschool; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 21; Core Binding Factor Alpha 2 Subunit; Diploidy; DNA-Binding Proteins; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; ETS Translocation Variant 6 Protein; Female; Gene Order; Humans; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ets; Repressor Proteins; Transcription Factors; Translocation, Genetic | 2004 |
Therapy-related acute myeloid leukemia-like MLL rearrangements are induced by etoposide in primary human CD34+ cells and remain stable after clonal expansion.
Topics: Acute Disease; Antigens, CD34; Cell Proliferation; Cells, Cultured; Clone Cells; DNA-Binding Proteins; Etoposide; Fetal Blood; Gene Rearrangement; Hematopoietic Stem Cells; Histone-Lysine N-Methyltransferase; Humans; Leukemia, Myeloid; Myeloid-Lymphoid Leukemia Protein; Neoplasms, Second Primary; Proto-Oncogenes; Transcription Factors; Translocation, Genetic | 2005 |
Secondary leukemia after first-line high-dose chemotherapy for patients with advanced germ cell cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials, Phase II as Topic; Etoposide; Follow-Up Studies; Germany; Germinoma; Humans; Ifosfamide; Leukemia, Myeloid, Acute; Male; Mediastinal Neoplasms; Multicenter Studies as Topic; Myelodysplastic Syndromes; Neoplasms, Second Primary; Paclitaxel; Peripheral Blood Stem Cell Transplantation; Testicular Neoplasms; Translocation, Genetic; Transplantation, Autologous | 2005 |
DNA topoisomerase II in therapy-related acute promyelocytic leukemia.
Topics: Antineoplastic Agents; DNA Damage; DNA Repair; DNA Topoisomerases, Type II; DNA, Neoplasm; Doxorubicin; Etoposide; Humans; In Vitro Techniques; Leukemia, Promyelocytic, Acute; Mitoxantrone; Neoplasms, Second Primary; Polymerase Chain Reaction; Sequence Analysis, DNA; Topoisomerase II Inhibitors; Translocation, Genetic | 2005 |
TLS/FUS-ERG fusion gene in acute lymphoblastic leukemia with t(16;21)(p11;q22) and monitoring of minimal residual disease.
Topics: Antineoplastic Combined Chemotherapy Protocols; Base Sequence; Chromosome Mapping; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 21; Cytarabine; Etoposide; Exons; Humans; Idarubicin; Infant; Male; Neoplasm, Residual; Oncogene Proteins, Fusion; Precursor Cell Lymphoblastic Leukemia-Lymphoma; RNA-Binding Protein FUS; Translocation, Genetic; Treatment Outcome | 2005 |
The prognostic value of MLL-AF9 detection in patients with t(9;11)(p22;q23)-positive acute myeloid leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 9; Cohort Studies; Combined Modality Therapy; Cytarabine; Etoposide; Humans; Idarubicin; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Multicenter Studies as Topic; Myeloid-Lymphoid Leukemia Protein; Neoplasm, Residual; Oncogene Proteins, Fusion; Peripheral Blood Stem Cell Transplantation; Polymerase Chain Reaction; Prognosis; Randomized Controlled Trials as Topic; Recurrence; Remission Induction; Survival Analysis; Translocation, Genetic; Treatment Outcome; Tretinoin | 2005 |
Early G2/M checkpoint failure as a molecular mechanism underlying etoposide-induced chromosomal aberrations.
Topics: Bone Neoplasms; Cell Cycle; Cell Division; Cell Line; Cell Line, Tumor; Chromosome Aberrations; Chromosome Banding; Chromosomes, Human, Pair 11; Cloning, Molecular; Etoposide; G2 Phase; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Humans; Myeloid-Lymphoid Leukemia Protein; Osteosarcoma; Translocation, Genetic | 2006 |
[Therapy-related acute promyelocytic leukemia with a t(9;22)(q34;q11) and t(15;17)(q22;q11 to approximately 12) subclone].
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 22; Chromosomes, Human, Pair 9; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Karyotyping; Leukemia, Promyelocytic, Acute; Prednisolone; Remission Induction; Translocation, Genetic; Tretinoin; Vincristine | 2005 |
Combined spectral karyotyping, comparative genomic hybridization, and in vitro apoptyping of a panel of Burkitt's lymphoma-derived B cell lines reveals an unexpected complexity of chromosomal aberrations and a recurrence of specific abnormalities in chemo
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; B-Lymphocytes; Burkitt Lymphoma; Cell Line, Tumor; Chromosome Aberrations; Chromosome Banding; Chromosome Breakage; DNA, Neoplasm; Drug Resistance, Neoplasm; Etoposide; Female; Genome, Human; Humans; Male; Nucleic Acid Hybridization; Polymerase Chain Reaction; Spectral Karyotyping; Translocation, Genetic | 2006 |
Retinoblastoma and deletion of the long arm of chromosome 13: an underestimated diagnosis?
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chromosome Deletion; Chromosomes, Human, Pair 13; Chromosomes, Human, Pair 8; Combined Modality Therapy; Etoposide; Eye Enucleation; False Negative Reactions; Female; Genes, Retinoblastoma; Humans; Hyperthermia, Induced; In Situ Hybridization, Fluorescence; Infant; Neoplasms, Multiple Primary; Remission Induction; Retinal Neoplasms; Retinoblastoma; Skull; Translocation, Genetic; Vincristine | 2008 |
Prognostic significance of WT1 gene expression in pediatric acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brazil; Child; Child, Preschool; Chromosome Inversion; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Daunorubicin; Etoposide; Female; Follow-Up Studies; Gene Expression Regulation, Leukemic; Genes, Wilms Tumor; Humans; Infant; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Male; Neoplasm Proteins; Prognosis; Proportional Hazards Models; Reverse Transcriptase Polymerase Chain Reaction; Survival Analysis; Translocation, Genetic; WT1 Proteins | 2007 |
Acute myelogenous leukemia associated with Ollier disease.
Topics: Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 21; Cytarabine; Daunorubicin; Enchondromatosis; Etoposide; Gemtuzumab; Graft vs Host Disease; Humans; Infant; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Neoplastic Syndromes, Hereditary; Translocation, Genetic | 2008 |
Complex chromosome 8;21 translocation with associated hyperdiploidy in acute myeloid leukemia (FAB-M2).
Topics: Aneuploidy; Antineoplastic Combined Chemotherapy Protocols; Child; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Core Binding Factor Alpha 2 Subunit; Cytarabine; Cytogenetic Analysis; Etoposide; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Nucleic Acid Hybridization; Oncogene Proteins, Fusion; Polymerase Chain Reaction; RUNX1 Translocation Partner 1 Protein; Translocation, Genetic | 2008 |
Dietary flavonoids induce MLL translocations in primary human CD34+ cells.
Topics: Antigens, CD34; Cells, Cultured; Dietary Supplements; DNA Breaks, Double-Stranded; Etoposide; Flavonoids; Genistein; Histone-Lysine N-Methyltransferase; Humans; Kaempferols; Leukemia; Leukocytes, Mononuclear; Myeloid-Lymphoid Leukemia Protein; Quercetin; Translocation, Genetic | 2007 |
[Early relapse of Burkitt's lymphoma with t(8;14) and t(14;18) after rituximab-combined CODOX-M and IVAC therapy].
Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 8; Cyclophosphamide; Cytarabine; Disease Progression; Doxorubicin; Etoposide; Fatal Outcome; Female; Humans; Ifosfamide; Methotrexate; Recurrence; Remission Induction; Rituximab; Translocation, Genetic; Vincristine | 2007 |
Genome scan implicates adhesion biological pathways in secondary leukemia.
Topics: Adolescent; Case-Control Studies; Cell Adhesion; Child; Child, Preschool; Cohort Studies; Etoposide; Female; Gene Frequency; Genome, Human; Humans; Infant; Leukemia; Loss of Heterozygosity; Male; Polymorphism, Single Nucleotide; Translocation, Genetic | 2007 |
Drug-induced Myc-mediated apoptosis of cancer cells is inhibited by stress protein Hsp70.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Camptothecin; Caspases; Cytochromes c; Enzyme Activation; Enzyme Inhibitors; Estrogens; Etoposide; Gene Expression Regulation, Neoplastic; HSP70 Heat-Shock Proteins; Humans; Lymphoma, Large B-Cell, Diffuse; Oncogene Proteins, Fusion; Proto-Oncogene Proteins c-myc; Translocation, Genetic; U937 Cells; Up-Regulation | 2007 |
Translocation (X;10) in a child with therapy-related acute myeloid leukemia following chemotherapy for Ewing's Sarcoma.
Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 10; Chromosomes, Human, X; Cyclophosphamide; Etoposide; Female; Humans; Ifosfamide; Leukemia, Myeloid, Acute; Sarcoma, Ewing; Translocation, Genetic | 2007 |
Repositioning of ETO gene in cells treated with VP-16, an inhibitor of DNA-topoisomerase II.
Topics: Cell Nucleus; Chromosome Breakage; Core Binding Factor Alpha 2 Subunit; DNA-Binding Proteins; Etoposide; Fibroblasts; Gene Rearrangement; Humans; Male; Myosins; Proto-Oncogene Proteins; RUNX1 Translocation Partner 1 Protein; Topoisomerase II Inhibitors; Transcription Factors; Translocation, Genetic | 2008 |
Prospective tracing of MLL-FRYL clone with low MEIS1 expression from emergence during neuroblastoma treatment to diagnosis of myelodysplastic syndrome.
Topics: Alkylating Agents; Animals; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Child, Preschool; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 4; Combined Modality Therapy; DNA Topoisomerases, Type II; Drosophila melanogaster; Etoposide; Gene Expression Regulation, Neoplastic; Granulocyte-Macrophage Colony-Stimulating Factor; Histone-Lysine N-Methyltransferase; Homeodomain Proteins; Humans; Male; Myelodysplastic Syndromes; Myeloid Ecotropic Viral Integration Site 1 Protein; Myeloid-Lymphoid Leukemia Protein; Neoplasm Proteins; Neuroblastoma; Oncogene Proteins, Fusion; Peripheral Blood Stem Cell Transplantation; Prospective Studies; Sequence Homology, Amino Acid; Topoisomerase II Inhibitors; Translocation, Genetic; Transplantation, Autologous | 2008 |
Therapy-related acute myelomonocytic leukemia following successful treatment for acute promyelocytic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 10; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cytarabine; Etoposide; Female; Humans; Idarubicin; Karyotyping; Leukemia, Myelomonocytic, Acute; Leukemia, Promyelocytic, Acute; Mercaptopurine; Methotrexate; Mitoxantrone; Neoplasms, Second Primary; Remission Induction; Thioguanine; Translocation, Genetic | 1995 |
Secondary leukemia associated with a conventional dose of etoposide: review of serial germ cell tumor protocols.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 4; Cisplatin; Clinical Trials as Topic; Etoposide; Humans; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Neoplasms, Germ Cell and Embryonal; Neoplasms, Second Primary; Retrospective Studies; Salvage Therapy; Testicular Neoplasms; Translocation, Genetic | 1993 |
ALL-1 gene rearrangements in DNA topoisomerase II inhibitor-related leukemia in children.
Topics: Acute Disease; Adolescent; Bone Marrow Transplantation; Child; Child, Preschool; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, Pair 11; Combined Modality Therapy; Dactinomycin; DNA-Binding Proteins; Etoposide; Female; Genes; Histone-Lysine N-Methyltransferase; Humans; Infant; Leukemia; Leukemia, Myeloid; Leukemia, Radiation-Induced; Male; Myelodysplastic Syndromes; Myeloid-Lymphoid Leukemia Protein; Neoplasm Proteins; Neoplasms; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogenes; Radiotherapy; Teniposide; Topoisomerase II Inhibitors; Transcription Factors; Translocation, Genetic; Whole-Body Irradiation | 1995 |
Acute promyelocytic leukemia with t(15;17) abnormality after chemotherapy containing etoposide for Langerhans cell histiocytosis.
Topics: Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Registries; Translocation, Genetic | 1995 |
Distinct MLL gene rearrangements associated with successive acute monocytic and lymphoblastic leukemias in the same patient.
Topics: Adult; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 4; Chromosomes, Human, Pair 6; Etoposide; Gene Rearrangement; Humans; In Situ Hybridization, Fluorescence; Leukemia, Monocytic, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Translocation, Genetic | 1994 |
Acute promyelocytic leukemia with t(15;17) abnormality after chemotherapy containing etoposide for Langerhans' cell histiocytosis.
Topics: Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Etoposide; Histiocytosis, Langerhans-Cell; Humans; Leukemia, Promyelocytic, Acute; Translocation, Genetic | 1994 |
Translocation t(11;11)(q13;q23) and HRX gene rearrangement associated with therapy-related leukemia in a child previously treated with VP16.
Topics: Adolescent; Blotting, Southern; Chromosomes, Human, Pair 11; DNA-Binding Proteins; Etoposide; Female; Gene Rearrangement; Histone-Lysine N-Methyltransferase; Humans; In Situ Hybridization, Fluorescence; Karyotyping; Leukemia, Monocytic, Acute; Leukemia, Myelomonocytic, Acute; Myeloid-Lymphoid Leukemia Protein; Neoplasms, Second Primary; Proto-Oncogenes; Transcription Factors; Translocation, Genetic | 1994 |
Acute myelomonocytic leukemia after treatment with chronic oral etoposide: are MLL and LTG9 genes targets for etoposide?
Topics: Administration, Oral; Aged; Base Sequence; Carcinoma, Small Cell; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 9; Drug Administration Schedule; Etoposide; Genes; Humans; Leukemia, Myelomonocytic, Acute; Lung Neoplasms; Male; Molecular Sequence Data; Neoplasms, Second Primary; Polymerase Chain Reaction; Translocation, Genetic | 1994 |
A non-classical translocation involving 17q12 (retinoic acid receptor alpha) in acute promyelocytic leukemia (APML) with atypical features.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Child, Preschool; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Karyotyping; Leukemia, Promyelocytic, Acute; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Thioguanine; Translocation, Genetic | 1994 |
[Secondary leukemia after etoposide treatment involved MLL gene rearrangement].
Topics: Chromosomes, Human, Pair 11; Etoposide; Gene Rearrangement; Humans; Leukemia, Myeloid, Acute; Lymphoma, T-Cell; Male; Middle Aged; Neoplasms, Second Primary; Translocation, Genetic | 1994 |
Therapy-related acute myelogenous leukemia associated with 11q23 chromosomal abnormalities and topoisomerase II inhibitors: report of four additional cases and brief commentary.
Topics: Adult; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 9; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Middle Aged; Neoplasms, Second Primary; Topoisomerase II Inhibitors; Translocation, Genetic | 1993 |
Translocation (2;4)(p23;q25): an additional case of a new recurrent anomaly in acute myeloid leukemia.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Banding; Chromosomes, Human, Pair 2; Chromosomes, Human, Pair 4; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Translocation, Genetic | 1993 |
Acute promyelocytic leukemia with t(15;17) abnormality after chemotherapy containing etoposide for Langerhans cell histiocytosis.
Topics: Child, Preschool; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Etoposide; Female; Histiocytosis, Langerhans-Cell; Humans; Infant; Leukemia, Promyelocytic, Acute; Translocation, Genetic | 1993 |
Human trithorax gene rearrangements in therapy-related acute leukaemia after etoposide treatment.
Topics: Adult; Aged; Animals; Blotting, Southern; Chromosomes, Human, Pair 11; Drosophila; Etoposide; Female; Gene Rearrangement; Genes, Regulator; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasms, Second Primary; Sequence Homology, Nucleic Acid; Translocation, Genetic | 1994 |
Common region of ALL-1 gene disrupted in epipodophyllotoxin-related secondary acute myeloid leukemia.
Topics: Child, Preschool; Chromosomes, Human, Pair 11; DNA-Cytosine Methylases; DNA, Neoplasm; Etoposide; Humans; Leukemia, Monocytic, Acute; Male; Neoplasms, Second Primary; Podophyllotoxin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Translocation, Genetic | 1993 |
Acute myeloid leukemia after single-agent treatment with etoposide for Langerhans' cell histiocytosis of bone.
Topics: Acute Disease; Bone Diseases; Child; Etoposide; Female; Histiocytosis, Langerhans-Cell; Humans; Leukemia, Myeloid; Translocation, Genetic | 1993 |
VP16 hypersensitivity and increased faulty recombination in ataxia telangiectasia lymphocytes characterized by the tandem translocation t(14;14)(q11;q32).
Topics: Adolescent; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Ataxia Telangiectasia; Bleomycin; Chromosomes, Human, Pair 14; Etoposide; Female; Humans; Sister Chromatid Exchange; T-Lymphocytes; Translocation, Genetic | 1996 |
Distribution of 11q23 breakpoints within the MLL breakpoint cluster region in de novo acute leukemia and in treatment-related acute myeloid leukemia: correlation with scaffold attachment regions and topoisomerase II consensus binding sites.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents, Phytogenic; Base Sequence; Binding Sites; Centromere; Child; Child, Preschool; Chromatin; Chromosomes, Human, Pair 11; Consensus Sequence; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Neoplasm; Etoposide; Female; Histone-Lysine N-Methyltransferase; Humans; Infant; Leukemia; Male; Middle Aged; Molecular Sequence Data; Myeloid-Lymphoid Leukemia Protein; Neoplasms, Second Primary; Proto-Oncogenes; Telomere; Teniposide; Topoisomerase II Inhibitors; Transcription Factors; Translocation, Genetic; Tumor Cells, Cultured | 1996 |
[Therapy-related AML(M2) with t(8;21) that developed three years after chemotherapy for hepatocellular carcinoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Hepatocellular; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Doxorubicin; Epirubicin; Etoposide; Humans; Leukemia, Myeloid, Acute; Liver Neoplasms; Male; Middle Aged; Neoplasms, Second Primary; Translocation, Genetic | 1996 |
Marked bone marrow eosinophilia at the time of relapse of acute myeloblastic leukaemia in association with the appearance of translocation t(12;20)(q24;q11).
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 20; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Daunorubicin; Eosinophilia; Etoposide; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Neoplasm Recurrence, Local; Remission Induction; Translocation, Genetic | 1996 |
t(9;13)(q34;q12) chromosomal translocation persisting 4 years post autologous bone marrow transplantation for secondary AML despite morphological remission.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Benzene; Bone Marrow; Bone Marrow Transplantation; Carmustine; Chromosomes, Human, Pair 13; Chromosomes, Human, Pair 9; Combined Modality Therapy; Etoposide; Follow-Up Studies; Humans; Leukemia, Myeloid; Male; Melphalan; Myelodysplastic Syndromes; Neoplastic Stem Cells; Occupational Diseases; Occupational Exposure; Pancytopenia; Remission Induction; Solvents; Translocation, Genetic; Transplantation, Homologous | 1996 |
Differentiation induction therapy with all-trans retinoic acid (ATRA) in a patient with secondary 11q23 leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, Pair 11; Cytarabine; Drug Resistance, Multiple; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Male; Translocation, Genetic; Tretinoin | 1996 |
[The detection of minimal residual disease by DEK/CAN chimeric m-RNA in a case of AML M2 with translocation t(6;9) (p23;q34) after chemotherapy and peripheral blood stem cell transplantation].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 6; Chromosomes, Human, Pair 9; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Mitoxantrone; Neoplasm, Residual; Oncogene Proteins; Oncogene Proteins, Fusion; Polymerase Chain Reaction; Prednisolone; Recombinant Fusion Proteins; RNA, Messenger; Translocation, Genetic | 1997 |
Risk of secondary leukemia after treatment with etoposide (VP-16) for Langerhans' cell histiocytosis in Italian and Austrian-German populations.
Topics: Adolescent; Adult; Age Factors; Austria; Child; Child, Preschool; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cohort Studies; Etoposide; Female; Follow-Up Studies; Germany; Histiocytosis, Langerhans-Cell; Humans; Infant; Infant, Newborn; Italy; Leukemia, Myeloid, Acute; Male; Netherlands; Risk Assessment; Sex Factors; Switzerland; Translocation, Genetic | 1997 |
Topoisomerase II inhibitors induce DNA double-strand breaks at a specific site within the AML1 locus.
Topics: Amsacrine; Antineoplastic Agents; Base Sequence; Cell Line; Dactinomycin; DNA Damage; DNA, Neoplasm; Doxorubicin; Etoposide; Genes, abl; Humans; Leukemia, Myeloid, Acute; Molecular Sequence Data; Monocytes; Restriction Mapping; Topoisomerase II Inhibitors; Translocation, Genetic | 1997 |
Translocation t(4;11)(q21;q23) and MLL gene rearrangement in acute lymphoblastic leukemia secondary to anti topoisomerase II anticancer agents.
Topics: Adult; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 11; DNA-Binding Proteins; Drug Resistance, Neoplasm; Etoposide; Female; Gene Rearrangement; Histone-Lysine N-Methyltransferase; Humans; Myeloid-Lymphoid Leukemia Protein; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogenes; Recurrence; Remission Induction; Topoisomerase II Inhibitors; Transcription Factors; Translocation, Genetic | 1997 |
DNA cleavage within the MLL breakpoint cluster region is a specific event which occurs as part of higher-order chromatin fragmentation during the initial stages of apoptosis.
Topics: Animals; Antineoplastic Agents; Apoptosis; Core Binding Factor Alpha 2 Subunit; DNA Fragmentation; DNA-Binding Proteins; Enzyme Inhibitors; Etoposide; Histone-Lysine N-Methyltransferase; Humans; Mice; Myeloid-Lymphoid Leukemia Protein; Proto-Oncogene Proteins; Proto-Oncogenes; Restriction Mapping; Species Specificity; Topoisomerase II Inhibitors; Transcription Factors; Translocation, Genetic; Tumor Cells, Cultured | 1997 |
Molecular analysis of the t(15;17) translocation in de novo and secondary acute promyelocytic leukemia.
Topics: Antineoplastic Agents, Phytogenic; Base Sequence; Blotting, Southern; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Consensus Sequence; Etoposide; Humans; Introns; Leukemia, Promyelocytic, Acute; Neoplasm Proteins; Neoplasms, Second Primary; Nuclear Proteins; Promyelocytic Leukemia Protein; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Transcription Factors; Translocation, Genetic; Tumor Suppressor Proteins | 1997 |
Calphostin C synergistically induces apoptosis with VP-16 in lymphoma cells which express abundant phosphorylated Bcl-2 protein.
Topics: Apoptosis; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 18; DNA Fragmentation; Drug Synergism; Etoposide; Humans; Lymphoma; Naphthalenes; Phosphoproteins; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Tetradecanoylphorbol Acetate; Translocation, Genetic; Tumor Cells, Cultured; Up-Regulation | 1997 |
Induction of chromosomal aberrations (unstable and stable) by inhibitors of topoisomerase II, m-AMSA and VP16, using conventional Giemsa staining and chromosome painting techniques.
Topics: Amsacrine; Azure Stains; Chromosome Aberrations; Chromosome Banding; Etoposide; Humans; Male; Staining and Labeling; Topoisomerase II Inhibitors; Translocation, Genetic | 1998 |
Secondary ANLL with t(11;19)(q23;p13) following etoposide and cisplatin for ovarian germ cell tumor.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 19; Cisplatin; Etoposide; Female; Germinoma; Humans; Leukemia, Myeloid, Acute; Ovarian Neoplasms; Translocation, Genetic | 1997 |
A case of therapy-related acute myeloblastic leukemia with t(16;21)(q24;q22) after chemotherapy with DNA-topoisomerase II inhibitors, etoposide and mitoxantrone, and the alkylating agent, cyclophosphamide.
Topics: Alkylating Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blotting, Southern; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 21; Cosmids; Cyclophosphamide; DNA Probes; DNA Topoisomerases, Type II; Etoposide; Female; Gene Deletion; Humans; In Situ Hybridization, Fluorescence; Leukemia, Myeloid, Acute; Leukemia, Radiation-Induced; Middle Aged; Mitoxantrone; Prednisone; Topoisomerase II Inhibitors; Translocation, Genetic | 1998 |
[Successful treatment with idarubicin in a pediatric case of t(8;21) acute myelogenous leukemia with additional chromosomal abnormalities at relapse].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Combined Modality Therapy; Cytarabine; Etoposide; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Recurrence; Remission Induction; Translocation, Genetic; Treatment Outcome | 1998 |
The frequency of illegitimate V(D)J recombinase-mediated mutations in children treated with etoposide-containing antileukemic therapy.
Topics: Base Sequence; Child; Child, Preschool; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 18; DNA Nucleotidyltransferases; Etoposide; Humans; Lymphocytes; Polymerase Chain Reaction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Translocation, Genetic; VDJ Recombinases | 1998 |
Characterization and chemosensitivity of two human malignant peripheral nerve sheath tumour cell lines derived from a patient with neurofibromatosis type 1.
Topics: Adult; Animals; DNA Primers; Doxorubicin; Drug Screening Assays, Antitumor; Etoposide; Female; Humans; Immunoenzyme Techniques; Karyotyping; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neurofibromatosis 1; Peripheral Nervous System Neoplasms; Polymerase Chain Reaction; Retroperitoneal Neoplasms; S100 Proteins; Translocation, Genetic; Tretinoin; Tumor Cells, Cultured | 1998 |
A novel t(Y;11) translocation with MLL gene rearrangement in a case of acute myelomonocytic leukemia (AML-M4)
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chromosome Banding; Chromosomes, Human, Pair 11; Cytarabine; DNA-Binding Proteins; Etoposide; Gene Rearrangement; Histone-Lysine N-Methyltransferase; Humans; In Situ Hybridization, Fluorescence; Karyotyping; Leukemia, Myelomonocytic, Acute; Male; Myeloid-Lymphoid Leukemia Protein; Proto-Oncogenes; Transcription Factors; Translocation, Genetic; Y Chromosome | 1999 |
Cryptic insertion (15;17) in a case of acute promyelocytic leukemia detected by fluorescence in situ hybridization.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cytarabine; Etoposide; Fatal Outcome; Hematopoietic Stem Cell Transplantation; Humans; In Situ Hybridization, Fluorescence; Leukemia, Promyelocytic, Acute; Male; Mitoxantrone; Neoplasm Proteins; Oncogene Proteins, Fusion; Reverse Transcriptase Polymerase Chain Reaction; Translocation, Genetic; Tretinoin | 1999 |
Acute promyelocytic leukemia after treatment for non-Hodgkin's lymphoma with drugs targeting topoisomerase II.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Bone Marrow; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Enzyme Inhibitors; Etoposide; Female; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Lymphoma, Non-Hodgkin; Middle Aged; Receptors, Retinoic Acid; Recurrence; Topoisomerase II Inhibitors; Translocation, Genetic; Tretinoin | 1999 |
Long-term molecular remission in promyelocytic transformation of myeloproliferative disease.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cytarabine; Daunorubicin; Disease Progression; Etoposide; Female; Humans; Idarubicin; Karyotyping; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Neoplasm Proteins; Oncogene Proteins, Fusion; Polycythemia Vera; Preleukemia; Prognosis; Remission Induction; Thrombocythemia, Essential; Thrombophilia; Translocation, Genetic; Tretinoin | 1999 |
The inv(11)(p15q22) chromosome translocation of therapy-related myelodysplasia with NUP98-DDX10 and DDX10-NUP98 fusion transcripts.
Topics: Cell Transformation, Neoplastic; Chromosomes, Human, Pair 11; Etoposide; Humans; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Male; Middle Aged; Neoplasms, Germ Cell and Embryonal; Neoplasms, Second Primary; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Transcription, Genetic; Translocation, Genetic | 1999 |
Small noncleaved, non-Burkitt's (Burkit-Like) lymphoma: cytogenetics predict outcome and reflect clinical presentation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Transplantation; Cyclophosphamide; Doxorubicin; Etoposide; Female; Gene Rearrangement; Genes, myc; Humans; Immunophenotyping; Karyotyping; Lymphoma, Non-Hodgkin; Male; Middle Aged; Prednisolone; Prednisone; Prognosis; Proto-Oncogene Proteins c-bcl-2; Survival Rate; Translocation, Genetic; Vincristine | 1999 |
RT-PCR evaluation of peripheral blood, bone marrow and peripheral blood stem cells in children and adolescents undergoing VACIME chemotherapy for Ewing's sarcoma and alveolar rhabdomyosarcoma.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Purging; Bone Neoplasms; Child; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 13; Chromosomes, Human, Pair 2; Chromosomes, Human, Pair 22; Combined Modality Therapy; Cyclophosphamide; DNA-Binding Proteins; Doxorubicin; Etoposide; Female; Forkhead Box Protein O1; Forkhead Transcription Factors; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Ifosfamide; Male; Mesna; Neoplasm Proteins; Neoplastic Cells, Circulating; Oncogene Proteins, Fusion; Paired Box Transcription Factors; PAX3 Transcription Factor; Proto-Oncogene Protein c-fli-1; Reverse Transcriptase Polymerase Chain Reaction; Rhabdomyosarcoma, Alveolar; RNA-Binding Protein EWS; Sarcoma, Ewing; Sensitivity and Specificity; Soft Tissue Neoplasms; Transcription Factors; Translocation, Genetic; Vincristine | 1999 |
The frequency of illegitimate TCRbeta/gamma gene recombination in human lymphocytes: influence of age, environmental exposure and cytostatic treatment, and correlation with frequencies of t(14;18) and hprt mutation.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 18; Etoposide; Gene Rearrangement, beta-Chain T-Cell Antigen Receptor; Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor; Humans; Hypoxanthine Phosphoribosyltransferase; Lymphocytes; Male; Middle Aged; Mutation; Testicular Neoplasms; Translocation, Genetic | 1999 |
[Mechanism of occurrence of secondary tumors by antitumor drugs].
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; DNA Repair; DNA Topoisomerases, Type II; DNA-Binding Proteins; Doxorubicin; Etoposide; Histone-Lysine N-Methyltransferase; Humans; Leukemia; Myeloid-Lymphoid Leukemia Protein; Neoplasms, Second Primary; Proto-Oncogenes; Topoisomerase II Inhibitors; Transcription Factors; Translocation, Genetic | 1999 |
Cell density-dependent VP-16 sensitivity of leukaemic cells is accompanied by the translocation of topoisomerase IIalpha from the nucleus to the cytoplasm.
Topics: Antineoplastic Agents, Phytogenic; Blotting, Western; Cell Nucleus; Cytoplasm; DNA Topoisomerases, Type I; Drug Resistance, Neoplasm; Etoposide; Flow Cytometry; Humans; Leukemia; Multiple Myeloma; Phenotype; Translocation, Genetic; Tumor Cells, Cultured | 2000 |
Detection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Base Sequence; Blotting, Southern; Chromosomes, Human, Pair 11; Cisplatin; Cyclophosphamide; DNA-Binding Proteins; Doxorubicin; Etoposide; Exons; Fatal Outcome; Histone-Lysine N-Methyltransferase; Humans; Leukemia, Myeloid; Male; Molecular Sequence Data; Myeloid-Lymphoid Leukemia Protein; Nerve Tissue Proteins; Neuroblastoma; Polymerase Chain Reaction; Proto-Oncogenes; Time Factors; Topoisomerase II Inhibitors; Transcription Factors; Translocation, Genetic; Vincristine | 2000 |
Fusion of the nucleoporin gene, NUP98, and the putative RNA helicase gene, DDX10, by inversion 11 (p15q22) chromosome translocation in a patient with etoposide-related myelodysplastic syndrome.
Topics: Antineoplastic Agents, Phytogenic; Artificial Gene Fusion; Chromosome Inversion; Chromosomes, Human, Pair 11; Cytogenetics; Enzyme Inhibitors; Etoposide; Germinoma; Humans; Male; Membrane Proteins; Middle Aged; Myelodysplastic Syndromes; Nuclear Pore Complex Proteins; Nuclear Proteins; Nucleic Acid Synthesis Inhibitors; Retroperitoneal Neoplasms; RNA Helicases; Topoisomerase II Inhibitors; Translocation, Genetic | 2000 |
Prognostic factors in children and adolescents with acute myeloid leukemia (excluding children with Down syndrome and acute promyelocytic leukemia): univariate and recursive partitioning analysis of patients treated on Pediatric Oncology Group (POG) Study
Topics: Adolescent; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bone Marrow Transplantation; Child; Chromosome Aberrations; Chromosome Inversion; Chromosomes, Human; Cohort Studies; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Life Tables; Male; Multicenter Studies as Topic; Prognosis; Proportional Hazards Models; Randomized Controlled Trials as Topic; Remission Induction; Risk Assessment; Risk Factors; Survival Analysis; Thioguanine; Translocation, Genetic; Treatment Failure; Treatment Outcome; United States | 2000 |
Breakage and fusion of the TEL (ETV6) gene in immature B lymphocytes induced by apoptogenic signals.
Topics: Aminophylline; Apoptosis; B-Lymphocytes; Base Sequence; Chromosome Breakage; Chromosome Mapping; Core Binding Factor Alpha 2 Subunit; Culture Media, Serum-Free; Etoposide; Humans; Hydrogen Peroxide; Infant, Newborn; Molecular Sequence Data; Oncogene Proteins, Fusion; Precursor Cell Lymphoblastic Leukemia-Lymphoma; RNA, Messenger; Salicylic Acid; Transcription, Genetic; Translocation, Genetic; Tumor Cells, Cultured | 2001 |
Etoposide metabolites enhance DNA topoisomerase II cleavage near leukemia-associated MLL translocation breakpoints.
Topics: Catechols; Chromosome Breakage; DNA Damage; DNA Topoisomerases, Type II; DNA-Binding Proteins; Enzyme Stability; Etoposide; Histone-Lysine N-Methyltransferase; Humans; Introns; Leukemia, Lymphoid; Leukemia, Myeloid; Myeloid-Lymphoid Leukemia Protein; Oligonucleotides; Proto-Oncogenes; Quinones; Substrate Specificity; Transcription Factors; Translocation, Genetic | 2001 |
Etoposide induces heritable chromosomal aberrations and aneuploidy during male meiosis in the mouse.
Topics: Aneuploidy; Animals; Antineoplastic Agents, Phytogenic; Chromosome Aberrations; Chromosomes; Etoposide; Karyotyping; Male; Meiosis; Metaphase; Mice; Spermatocytes; Translocation, Genetic | 2001 |
Near-precise interchromosomal recombination and functional DNA topoisomerase II cleavage sites at MLL and AF-4 genomic breakpoints in treatment-related acute lymphoblastic leukemia with t(4;11) translocation.
Topics: Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Catechols; Child; Chromosome Breakage; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 4; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Neoplasm; Etoposide; Female; Histone-Lysine N-Methyltransferase; Humans; Ifosfamide; Isoenzymes; Models, Genetic; Molecular Sequence Data; Myeloid-Lymphoid Leukemia Protein; Neoplasm Proteins; Neoplasms, Second Primary; Nuclear Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogenes; Radiotherapy, Adjuvant; Recombination, Genetic; Rhabdomyosarcoma, Alveolar; Soft Tissue Neoplasms; Transcription Factors; Transcriptional Elongation Factors; Translocation, Genetic; Vincristine | 2001 |
Acute myeloid leukemia with t(11;19)(q23;p13) developing in an adult T-cell leukemia patient treated with combined chemotherapy including etoposide.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 19; Etoposide; Female; Humans; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myeloid; Middle Aged; Neoplasms, Second Primary; Translocation, Genetic | 2001 |
Autologous stem cell transplantation for advanced acute myeloid leukemia.
Topics: Adult; Aged; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cell Count; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cytarabine; Cytogenetics; Disease-Free Survival; Etoposide; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Middle Aged; Prognosis; Translocation, Genetic; Transplantation, Autologous | 2002 |
Translocation (11;11)(p13- p15;q23) in a child with therapy-related acute myeloid leukemia following chemotherapy with DNA-topoisomerase II inhibitors for Langerhans cell histiocytosis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Chromosomes, Human, Pair 11; Cytarabine; Drug Therapy, Combination; Enzyme Inhibitors; Etoposide; Fatal Outcome; Histiocytosis, Langerhans-Cell; Humans; Idarubicin; Karyotyping; Leukemia, Myelomonocytic, Acute; Male; Neoplasms, Second Primary; Nuclear Pore Complex Proteins; Prednisolone; Topoisomerase II Inhibitors; Translocation, Genetic; Vinblastine | 2002 |
Patchy polyneuropathy in acute promyelocytic leukaemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Combined Modality Therapy; Cytarabine; Daunorubicin; Disseminated Intravascular Coagulation; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Male; Paraneoplastic Syndromes; Peripheral Nervous System Diseases; Remission Induction; Translocation, Genetic; Transplantation, Homologous | 1992 |
Constitutional translocation (8;13) in a patient with non-Hodgkin's lymphoma.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow; Chromosome Banding; Chromosomes, Human, Pair 13; Chromosomes, Human, Pair 8; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Karyotyping; Lymphoma, Non-Hodgkin; Male; Prednisone; Translocation, Genetic; Vincristine | 1992 |
Proof of differentiative mode of action of all-trans retinoic acid in acute promyelocytic leukemia using X-linked clonal analysis.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Blotting, Southern; Bone Marrow; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Clone Cells; Cytarabine; Daunorubicin; DNA, Neoplasm; Etoposide; Female; Genetic Linkage; Humans; Leukemia, Promyelocytic, Acute; Translocation, Genetic; Tretinoin; X Chromosome | 1992 |
Novel translocation (2;4) with consistent involvement of 2p23 in acute nonlymphocytic leukemia (M2).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 2; Chromosomes, Human, Pair 4; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Remission Induction; Translocation, Genetic | 1992 |
Successful treatment of acute leukemia with t(4;11) in an infant with congenital hypothyroidism.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Differentiation; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 4; Congenital Hypothyroidism; Cranial Irradiation; Cytarabine; Doxorubicin; Etoposide; Female; Humans; Hypothyroidism; Infant; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Translocation, Genetic; Vincristine | 1990 |
Acute nonlymphocytic leukemia with basophilic differentiation and t(9,11)(p22,q23) in a child.
Topics: Antineoplastic Combined Chemotherapy Protocols; Basophils; Cell Differentiation; Chromosome Banding; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 9; Etoposide; Humans; Infant; Leukemia, Myeloid, Acute; Male; Translocation, Genetic | 1989 |