etoposide has been researched along with Chromosomal Breakage in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 13 (61.90) | 29.6817 |
| 2010's | 6 (28.57) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Brazina, J; Caldecott, KW; Huybrechts, W; Molenaers, G; Van Den Bogaert, K; Van Esch, H; Zagnoli-Vieira, G | 1 |
| Caldecott, KW; Callen, E; Canela, A; Day, A; Huang, SN; Maman, Y; Nussenzweig, A; Peters, JM; Pommier, Y; Tang, W; Wong, N; Wutz, G; Zagnoli-Vieira, G | 1 |
| Austin, CA; Cowell, IG; Smith, KA; Sondka, Z; Zhang, Y | 1 |
| Filipic, M; Knasmueller, S; Mišík, M; Nersesyan, A; Pichler, C; Rainer, B | 1 |
| Lehman, CE; Pierce, LC; Thys, RG; Wang, YH | 1 |
| Mizutani, S; Nanya, M; Sato, M; Takagi, M; Tanimoto, K; Tozuka, M | 1 |
| Brooks, CF; Croken, MM; Francia, ME; Gissot, M; Kim, K; Striepen, B | 1 |
| Eguchi, M; Eguchi-Ishimae, M; Fujita, I; Hamasaki, Y; Ishii, E; Miyazaki, S; Mizutani, S; Oda, M; Yoshida, N; Zaitsu, M | 1 |
| Beck, JD; Borkhardt, A; Creutzig, U; Harbott, J; Jacobs, U; Langer, T; Leis, T; Metzler, M; Rascher, W; Reichel, M; Reinhardt, D; Repp, R; Ritter, J; Schrappe, M; Stanulla, M; Viehmann, S | 1 |
| Distel, L; Grabenbauer, G; Holter, W; Neubauer, S; Varon, R | 1 |
| Bender, RP; Burden, DA; Lindsey, RH; Osheroff, N | 1 |
| Cassina, G; Di-Tomaso, MV; Folle, GA; Martínez-López, W; Méndez-Acuña, L; Obe, G; Palitti, F | 1 |
| Blennow, E; Ernberg, I; Fadeel, B; Henter, JI; Karpova, MB; Nordenskjöld, M; Schoumans, J; Smirnov, AF | 1 |
| Kulms, D; Pöppelmann, B; Schwarz, T; Strozyk, E | 1 |
| Libura, J; Richardson, C; Sung, PA | 1 |
| Kantidze, OL; Razin, SV | 1 |
| Iarovaia, OV; Razin, SV; Rubtsov, MA; Terekhov, SM | 1 |
| Eckardt-Schupp, F; Friedl, AA; Jaspers, NG; Klein, B; Kraakman-van der Zwet, M; Lohman, PH; Midro, AT; Overkamp, WJ; Verhaegh, GW; Zdzienicka, MZ | 1 |
| Eguchi, M; Eguchi-Ishimae, M; Ishii, E; Kamada, N; Miyazaki, S; Mizutani, S; Ueda, K | 1 |
| Blair, IA; Burden, DA; Felix, CA; Lovett, BD; Megonigal, MD; Osheroff, N; Pang, S; Pommier, YG; Rappaport, EF; Rebbeck, TR; Strumberg, D | 1 |
| Blair, IA; Felix, CA; Lo Nigro, L; Lovett, BD; Megonigal, MD; Nowell, PC; Osheroff, N; Rappaport, EF; Williams, WR; Zheng, N | 1 |
1 review(s) available for etoposide and Chromosomal Breakage
| Article | Year |
|---|---|
Etoposide and illegitimate DNA double-strand break repair in the generation of MLL translocations: new insights and new questions.
Topics: Antineoplastic Agents, Phytogenic; Chromosome Breakage; Chromosomes, Human, Pair 11; DNA Damage; DNA Repair; DNA Topoisomerases, Type II; Etoposide; Histone-Lysine N-Methyltransferase; Humans; Leukemia, Myeloid, Acute; Models, Genetic; Myeloid-Lymphoid Leukemia Protein; Sensitivity and Specificity; Topoisomerase II Inhibitors | 2006 |
20 other study(ies) available for etoposide and Chromosomal Breakage
| Article | Year |
|---|---|
Inactivating TDP2 missense mutation in siblings with congenital abnormalities reminiscent of fanconi anemia.
Topics: Chromosome Breakage; DNA; DNA Topoisomerases, Type II; DNA-Binding Proteins; Etoposide; Fanconi Anemia; Humans; Mutation, Missense; Phosphoric Diester Hydrolases; Siblings | 2023 |
Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity.
Topics: Chromosome Breakage; Chromosomes; DNA; DNA Breaks, Double-Stranded; DNA Repair; DNA Topoisomerases, Type II; DNA-Binding Proteins; Etoposide; Gene Conversion; HCT116 Cells; Humans; Kinetics; Multiprotein Complexes; Poly-ADP-Ribose Binding Proteins; Topoisomerase II Inhibitors; Torsion, Mechanical; Transcription, Genetic; Translocation, Genetic | 2019 |
The role of topoisomerase II beta on breakage and proximity of RUNX1 to partner alleles RUNX1T1 and EVI1.
Topics: Antineoplastic Agents; Base Sequence; Cell Line, Tumor; Chromatin; Chromosome Breakage; Core Binding Factor Alpha 2 Subunit; DNA Breaks, Double-Stranded; DNA Topoisomerases, Type II; DNA-Binding Proteins; Etoposide; Humans; MDS1 and EVI1 Complex Locus Protein; Molecular Sequence Data; Poly-ADP-Ribose Binding Proteins; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogene Proteins; Proto-Oncogenes; RUNX1 Translocation Partner 1 Protein; Transcription Factors; Translocation, Genetic | 2014 |
Acute toxic and genotoxic activities of widely used cytostatic drugs in higher plants: Possible impact on the environment.
Topics: Allium; Aneuploidy; Chromosome Breakage; Cyclophosphamide; Cytostatic Agents; Etoposide; Fluorouracil; Micronucleus Tests; No-Observed-Adverse-Effect Level; Organoplatinum Compounds; Plant Roots; Pollen; Toxicity Tests; Tradescantia; Vincristine | 2014 |
Environmental and chemotherapeutic agents induce breakage at genes involved in leukemia-causing gene rearrangements in human hematopoietic stem/progenitor cells.
Topics: Benzene; Bone Marrow Cells; Chromosome Breakage; Core Binding Factor beta Subunit; Diethylnitrosamine; DNA Damage; DNA Topoisomerases, Type II; Doxorubicin; Etoposide; Gene Rearrangement; Genome, Human; Hematopoietic Stem Cells; Histone-Lysine N-Methyltransferase; Humans; Leukemia; Myeloid-Lymphoid Leukemia Protein; Primary Cell Culture | 2015 |
Dysregulation of the DNA Damage Response and KMT2A Rearrangement in Fetal Liver Hematopoietic Cells.
Topics: Animals; Bone Marrow Cells; Carcinogenesis; Cell Cycle; Chromosome Breakage; DNA Breaks, Double-Stranded; DNA Damage; Etoposide; Female; Fetus; Gene Rearrangement; Hematopoietic Stem Cells; Histone-Lysine N-Methyltransferase; Histones; Injections, Intraperitoneal; Leukemia; Liver; Maternal Exposure; Mice, Inbred C57BL; Mice, Knockout; Myeloid-Lymphoid Leukemia Protein | 2015 |
Toxoplasma gondii sequesters centromeres to a specific nuclear region throughout the cell cycle.
Topics: Cell Cycle; Centromere; Chromatin Immunoprecipitation; Chromosome Breakage; Etoposide; Fluorescent Antibody Technique; Histones; Humans; Lysine; Methylation; Mitosis; Oligonucleotide Array Sequence Analysis; Reproducibility of Results; Toxoplasma | 2011 |
In vitro cleavage of the MLL gene by topoisomerase II inhibitor (etoposide) in normal cord and peripheral blood mononuclear cells.
Topics: Child; Child, Preschool; Chromosome Breakage; DNA-Binding Proteins; Enzyme Inhibitors; Etoposide; Fetal Blood; Gene Rearrangement; Histone-Lysine N-Methyltransferase; Humans; Infant; Infant, Newborn; Myeloid-Lymphoid Leukemia Protein; Proto-Oncogenes; Topoisomerase II Inhibitors; Transcription Factors | 2002 |
Analysis of t(9;11) chromosomal breakpoint sequences in childhood acute leukemia: almost identical MLL breakpoints in therapy-related AML after treatment without etoposides.
Topics: Acute Disease; Adolescent; Amino Acid Sequence; Child; Child, Preschool; Chromosome Breakage; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 9; DNA-Binding Proteins; Etoposide; Female; Histone-Lysine N-Methyltransferase; Humans; Infant; Leukemia, Myeloid; Male; Molecular Sequence Data; Myeloid-Lymphoid Leukemia Protein; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Nuclear Proteins; Oncogene Proteins, Fusion; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogenes; Transcription Factors; Tumor Cells, Cultured | 2003 |
Fatal toxicity following radio- and chemotherapy of medulloblastoma in a child with unrecognized Nijmegen breakage syndrome.
Topics: Abnormalities, Multiple; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Cell Cycle Proteins; Child; Chromosome Breakage; Cisplatin; Cytarabine; Death, Sudden, Cardiac; Etoposide; Fatal Outcome; Humans; Ifosfamide; Infratentorial Neoplasms; Male; Medulloblastoma; Methotrexate; Nuclear Proteins; Polymerase Chain Reaction; Syndrome | 2003 |
N-acetyl-p-benzoquinone imine, the toxic metabolite of acetaminophen, is a topoisomerase II poison.
Topics: Acetaminophen; Antigens, Neoplasm; Antineoplastic Agents; Benzoquinones; Cell Line, Tumor; Chromosome Breakage; DNA Damage; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA-Binding Proteins; Etoposide; Humans; Imines; Mutagens; Topoisomerase II Inhibitors | 2004 |
Distribution of breakpoints induced by etoposide and X-rays along the CHO X chromosome.
Topics: Animals; CHO Cells; Chromatids; Chromosome Aberrations; Chromosome Breakage; Chromosome Mapping; Cricetinae; Cricetulus; DNA; DNA Damage; Enzyme Inhibitors; Etoposide; Female; S Phase; Topoisomerase II Inhibitors; X Chromosome | 2004 |
Combined spectral karyotyping, comparative genomic hybridization, and in vitro apoptyping of a panel of Burkitt's lymphoma-derived B cell lines reveals an unexpected complexity of chromosomal aberrations and a recurrence of specific abnormalities in chemo
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; B-Lymphocytes; Burkitt Lymphoma; Cell Line, Tumor; Chromosome Aberrations; Chromosome Banding; Chromosome Breakage; DNA, Neoplasm; Drug Resistance, Neoplasm; Etoposide; Female; Genome, Human; Humans; Male; Nucleic Acid Hybridization; Polymerase Chain Reaction; Spectral Karyotyping; Translocation, Genetic | 2006 |
Differential effects of NF-kappaB on apoptosis induced by DNA-damaging agents: the type of DNA damage determines the final outcome.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Chromosome Breakage; Cisplatin; Comet Assay; DNA Damage; Doxorubicin; Etoposide; Gamma Rays; Gene Expression Regulation; Humans; I-kappa B Kinase; I-kappa B Proteins; Interleukin-1; Interleukin-6; KB Cells; Leupeptins; NF-kappa B; NF-KappaB Inhibitor alpha; Nitriles; Proteasome Inhibitors; Receptors, Tumor Necrosis Factor, Type I; RNA, Messenger; Sulfones; Transcription, Genetic; Tumor Necrosis Factor-alpha; Ultraviolet Rays | 2006 |
Chemotherapy-related secondary leukemias: A role for DNA repair by error-prone non-homologous end joining in topoisomerase II - Induced chromosomal rearrangements.
Topics: Antineoplastic Agents, Phytogenic; Chromatin Immunoprecipitation; Chromosome Aberrations; Chromosome Breakage; Core Binding Factor Alpha 2 Subunit; DNA Breaks, Double-Stranded; DNA Repair; DNA Topoisomerases, Type II; Drug-Related Side Effects and Adverse Reactions; Etoposide; Humans; Jurkat Cells; Leukemia; Neoplasms; Protein Binding; Rad52 DNA Repair and Recombination Protein; Recombination, Genetic; Topoisomerase II Inhibitors | 2007 |
Repositioning of ETO gene in cells treated with VP-16, an inhibitor of DNA-topoisomerase II.
Topics: Cell Nucleus; Chromosome Breakage; Core Binding Factor Alpha 2 Subunit; DNA-Binding Proteins; Etoposide; Fibroblasts; Gene Rearrangement; Humans; Male; Myosins; Proto-Oncogene Proteins; RUNX1 Translocation Partner 1 Protein; Topoisomerase II Inhibitors; Transcription Factors; Translocation, Genetic | 2008 |
Immortalization and characterization of Nijmegen Breakage syndrome fibroblasts.
Topics: Abnormalities, Multiple; Antineoplastic Agents; Bleomycin; Camptothecin; Cell Line; Cell Line, Transformed; Cell Survival; Cell Transformation, Viral; Child, Preschool; Chromosome Breakage; DNA; DNA Damage; DNA Repair; Etoposide; Fibroblasts; HeLa Cells; Humans; Mitomycin; Mutation; Syndrome; X-Rays | 1999 |
Breakage and fusion of the TEL (ETV6) gene in immature B lymphocytes induced by apoptogenic signals.
Topics: Aminophylline; Apoptosis; B-Lymphocytes; Base Sequence; Chromosome Breakage; Chromosome Mapping; Core Binding Factor Alpha 2 Subunit; Culture Media, Serum-Free; Etoposide; Humans; Hydrogen Peroxide; Infant, Newborn; Molecular Sequence Data; Oncogene Proteins, Fusion; Precursor Cell Lymphoblastic Leukemia-Lymphoma; RNA, Messenger; Salicylic Acid; Transcription, Genetic; Translocation, Genetic; Tumor Cells, Cultured | 2001 |
Etoposide metabolites enhance DNA topoisomerase II cleavage near leukemia-associated MLL translocation breakpoints.
Topics: Catechols; Chromosome Breakage; DNA Damage; DNA Topoisomerases, Type II; DNA-Binding Proteins; Enzyme Stability; Etoposide; Histone-Lysine N-Methyltransferase; Humans; Introns; Leukemia, Lymphoid; Leukemia, Myeloid; Myeloid-Lymphoid Leukemia Protein; Oligonucleotides; Proto-Oncogenes; Quinones; Substrate Specificity; Transcription Factors; Translocation, Genetic | 2001 |
Near-precise interchromosomal recombination and functional DNA topoisomerase II cleavage sites at MLL and AF-4 genomic breakpoints in treatment-related acute lymphoblastic leukemia with t(4;11) translocation.
Topics: Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Catechols; Child; Chromosome Breakage; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 4; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Neoplasm; Etoposide; Female; Histone-Lysine N-Methyltransferase; Humans; Ifosfamide; Isoenzymes; Models, Genetic; Molecular Sequence Data; Myeloid-Lymphoid Leukemia Protein; Neoplasm Proteins; Neoplasms, Second Primary; Nuclear Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogenes; Radiotherapy, Adjuvant; Recombination, Genetic; Rhabdomyosarcoma, Alveolar; Soft Tissue Neoplasms; Transcription Factors; Transcriptional Elongation Factors; Translocation, Genetic; Vincristine | 2001 |