etoposide has been researched along with Carcinoma, Oat Cell in 1349 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 286 (21.20) | 18.7374 |
1990's | 613 (45.44) | 18.2507 |
2000's | 365 (27.06) | 29.6817 |
2010's | 73 (5.41) | 24.3611 |
2020's | 12 (0.89) | 2.80 |
Authors | Studies |
---|---|
Feringa, BL; Jansen, JF; Kellogg, RM; Konings, AW; Middel, O; Pras, N; van Oeveren, A; van Uden, W; Woerdenbag, HJ | 1 |
Chen, AY; Cheng, CC; Chou, TC; Dong, Q; Liu, DF; Liu, LF; Luo, YL; Savaraj, N; Yu, C | 1 |
Hara, S; Hata, A; Komatsu, M; Ninomaru, T | 1 |
Bal, A; Gupta, N; Gupta, P; Khosla, D; Shastri, M; Singh, N; Srinivasan, R | 1 |
Ando, T; Hanai, K; Kamitani, R; Kashizaki, F; Mizuno, R; Sekido, Y; Tanaka, A | 1 |
Huang, Z; Zhang, Y | 1 |
Kimura, T; Kurita, T; Miyoshi, AI; Ueda, Y; Yoshino, K | 1 |
Al Tamimi, NS; Belbaraka, R; Bennouna, Y; El Fadli, M | 1 |
Alía Navarro, V; Barrill Corpa, AM; De Frutos González, B; Ferreiro Monteagudo, R; Ferrer Gómez, A; Martínez Delfrade, Í; Morón García, B; Peñas García, B; Perna Monroy, C; Sotoca Rubio, P | 1 |
Gunturu, KS; Ho, D; Raibagkar, P; Srinivasan, J | 1 |
Difilippantonio, S; Huang, SN; James, A; Marzi, L; Pommier, Y; Sun, Y | 1 |
Alexandre, J; Bello-Roufai, D; Berton, D; Blanc-Durand, F; Chaltiel, D; Collard, O; Dupre, PF; Fabbro, M; Faller, É; Floquet, A; Genestie, C; Guillemet, C; Hardy-Bressard, AC; Kalbacher, E; Lefeuvre-Plesse, C; Meriaux, É; Pautier, P; Provansal, M; Ray-Coquard, I | 1 |
Fuchigami, Y; Iguchi, R; Magaribuchi, T; Naito, H; Ota, H; Shibasaki, N; Terai, A; Tsuruta, M; Yamaguchi, T | 1 |
Jiao, N; Shi, L; Wang, B | 1 |
Al-Hanayneh, M; Bilal, M; Shabot, JM; Simoes, C | 1 |
Chen, X; Wang, XX; Xue, LW; Yin, DD | 1 |
Hashizume, A; Jikuya, R; Kawai, M; Kishida, T; Mizuno, N; Muraoka, K; Tatenuma, T; Umemoto, S; Washimi, K; Yasui, M | 1 |
Cheng, Y; He, T; Pei, X; Wu, X; Xiang, L; Yang, H; Yang, W; Ye, S | 1 |
Filipiak, KJ; Kowalik, R; Płatek, AE; Szymanski, FM | 1 |
Annala, M; Beltran, H; Chedgy, EC; Chi, KN; Donoghue, AJ; Fazli, L; Herberts, C; Hurtado-Coll, A; Konomura, S; Liew, J; Parimi, S; Ritch, E; Sboner, A; Sigouros, M; Struss, W; Vandekerkhove, G; Vergidis, J; Wyatt, AW | 1 |
Hattori, H; Inagaki, H; Murakami, S; Nakamura, Y; Nakayama, M; Ozaki, S; Suzuki, M; Yokota, M | 1 |
Binninger, A; Dille, S; Elender, C; Hutzschenreuter, U; Jänicke, M; Marschner, N; Spring, L; Steffens, CC | 1 |
Akhtar, T; Mangla, A | 1 |
Abonyi-Tóth, Z; Katona, L; Kovács, G; Moldvay, J; Rokszin, G | 1 |
Jett, JR; Kalemkerian, GP; Kesler, KA; Schild, SE | 1 |
Brasch, F; Gehl, HB; Görner, M; Hirnle, P; Scholtz, LU; Sudhoff, H; Wegehenkel, K | 1 |
Al-Jiffry, BO; Al-Malki, O | 1 |
Hosokawa, S; Mineta, H; Okamura, J; Takizawa, Y | 1 |
Bakalos, G; Doxani, C; Miligkos, M; Mpoulimari, I; Rodopoulou, P; Zintzaras, E | 1 |
Liu, H; Shan, Y; Tian, YT; Wang, CF; Xie, YB; Xu, Q; Yuan, XH; Zhang, JW; Zhao, DB; Zhou, ZX | 1 |
Feng, R; Jiang, S; Meng, X; Wang, R; Xu, X; Yan, H; Zhu, K | 1 |
Harada, M; Hida, T; Imamura, F; Ishikura, S; Kawahara, M; Kubota, K; Matsui, K; Mizusawa, J; Nakagawa, K; Negoro, S; Nishio, M; Okamoto, H; Saijo, N; Sakai, H; Shibata, T; Shinkai, T; Takeda, K; Tamura, T; Yamamoto, N; Yokoyama, A | 1 |
Chohnabayashi, N; Ishikawa, G; Jinta, T; Kitamura, A; Mochizuki, S; Nishimura, N; Suzuki, K; Tomishima, Y; Yamano, Y | 1 |
Bryant, CM; Dang, LH; Gilbert, SM; Morris, CG; Stechmiller, BK; Zlotecki, RA | 1 |
Cheng, XL; Huang, L; Liao, LM; Lin, JX; Liu, AW; Wu, JB; Zheng, M | 1 |
Bahri, M; Ben Amar, M; Ben Salah, H; Daoud, J; Kallel, N; Lahmar, R | 1 |
Bellefqih, S; Benjaafar, N; Kebdani, T; Khalil, J; Mezouri, I | 1 |
Buil-Bruna, N; López-Picazo, JM; Martín-Algarra, S; Moreno-Jiménez, M; Ribba, B; Trocóniz, IF | 1 |
Liu, SX; Wang, HY; Yan, JQ; Zhou, GY; Zou, J | 1 |
Akhurst, T; Cullinane, C; Eu, P; Hicks, RJ; Lewin, J; Mileshkin, L; Rao, A; Waldeck, K; Watkins, DN | 1 |
Akahane, K; Fujii, M; Kawada, K; Murata, T; Oda, K; Ohama, T; Yatabe, Y | 1 |
Haba, R; Hoshikawa, H; Miyashita, T; Shibata, T; Takahashi, S; Togami, T | 1 |
Ambrosio, F; Ardizzoni, A; Baldini, E; Boni, L; Camerini, A; Cinieri, S; Crino, L; D'Alessandro, V; Dazzi, C; Defraia, E; Passalacqua, R; Riccardi, F; Tibaldi, C; Tiseo, M; Turolla, GM; Vitale, MG; Zanelli, F; Zilembo, N | 1 |
Bentayeb, H; Cotrel, R; Dayen, C; Douadi, Y; Garoute, C; Iacob, E; Lecuyer, E; Plouvier, N; Suguenot, R | 1 |
Komune, S; Nakashima, T; Toh, S; Yamauchi, M; Yasumatsu, R | 1 |
Asari, Y; Itoga, M; Kayaba, H; Morimoto, T; Nakamura, K; Okumura, K; Taima, K; Takanashi, S; Tanaka, H; Tanaka, Y | 1 |
Fang, J; Liu, LF; Wu, MJ; Yin, ZM; Yu, AJ; Yu, H; Zhu, JQ | 1 |
Koo, DH; Lee, HS; Lee, SS; Lee, YG; Lim, SY; Nam, H; Oh, S; Song, JU | 1 |
Allendorf, DJ; Bordoni, RE; Dixon, PM; Grant, SC; Jerome, ML; Miley, DK; Reddy, VB; Robert, F; Saleh, MN; Singh, KP | 1 |
Bonventre, JV; Ichimura, T; Ikemi, Y; Kim, YH; Masuda, S; Matsubara, K; Mishima, M; Ozawa, A; Sato, T; Shinke, H; Togashi, Y | 1 |
Arora, S; Baghmar, S; Bhasker, S; Chander, S; Gogia, A; Kumar, R; Nath, D; Sahai, P; Sikka, K | 1 |
Akimoto, Y; Harada, R; Hata, H; Horiguchi, S; Kato, H; Matsumoto, K; Noma, Y; Okada, H; Sakae, H; Tomoda, T; Tsutsumi, K; Uchida, D; Yagi, T; Yamamoto, K; Yamamoto, N; Yanai, H | 1 |
Hirai, M; Kobayashi, Y; Konishi, T; Miyagawa, T; Nokubi, M; Saito, K; Washino, S | 1 |
Deng, W; Li, N; Luo, S; Shen, W; Wei, C | 1 |
Arai, H; Honda, M; Kobayashi, Y; Ueda, N; Yoshida, K | 1 |
Jang, TW; Jeong, JH; Kim, KS; Kim, SY; Kim, YC; Lee, HK; Lee, JE; Lee, KH; Lee, KY; Lee, SY; Oh, IJ; Park, CK; Shin, KC | 1 |
Jeong, JS; Kim, SR; Lee, JH; Lee, YC | 1 |
Heidegger, I; Horninger, W; Pichler, R; Schäfer, G; Tulchiner, G | 1 |
Asakura, T; Nin, M; Okada, T; Satoh, M; Tsujihata, M; Yumiba, S | 1 |
Ito, N; Kamba, T; Kamoto, T; Kanematsu, A; Masui, K; Nakamura, E; Nishiyama, H; Ogawa, O; Soda, T; Watanabe, J; Yoshimura, K | 1 |
Aschroft, L; Baka, S; Blackhall, F; Califano, R; Faivre-Finn, C; Ferraldeschi, R; Lorigan, P; Taylor, P; Thatcher, N | 1 |
Azad, A; Chionh, F; Lee, C | 1 |
Aasebø, U; Bergman, B; Bremnes, R; Ek, L; Fluge, S; Hermes, A; Sederholm, C; Sörenson, S; Sundstrøm, S; Thaning, L; Vilsvik, J | 1 |
Antoniou, D; Athanasiadis, A; Dimitroulis, J; Giamboudakis, P; Karaindros, D; Katis, K; Koutantos, J; Rapti, A; Rigatos, S; Stathopoulos, GP; Stathopoulos, J; Toumbis, M; Tsikritsaki, K | 1 |
Hirami, Y; Kawagoe, N; Mandai, M; Mio, T; Mishima, M; Sakuma, K; Takahashi, M; Yoshimura, N | 1 |
Abu-Rustum, NR; Aghajanian, C; Alektiar, K; Chi, DS; Diaz, JP; Konner, J; Leitao, MM; Park, KJ; Zhao, H; Zivanovic, O | 1 |
Sun, YK; Wang, JW; Zhan, XK; Zhang, W | 1 |
Arcaro, A; Dhillon, T; Lane, HA; Lemoine, NR; Marinov, M; Mauri, FA; Pardo, OE; Seckl, MJ; Tan, LT; Zangemeister-Wittke, U; Ziogas, A | 1 |
Bernardo, P; Horn, L; Johnson, DH; Levitan, N; Levitt, ML; Sandler, A; Wagner, H | 1 |
Chikugo, T; Kitano, M; Komaki, T; Kudo, M; Noda, K; Sakamoto, H | 1 |
Dinney, CP; Grossman, HB; Kamat, AM; Millikan, RE; Qiao, W; Siefker-Radtke, AO; Thall, PF; Williams, DL | 1 |
Egan, A; Khan, MF; Martin, ST; Ryan, RS; Tobbia, I; Waldron, R; Walshe, T | 1 |
Castellino, SM; Hurt, G; Martinez-Borges, AR; Petty, JK; Press, JZ; Stribling, JT | 1 |
Grün, R; Koch, B; Tannapfel, A; Vieth, M | 1 |
Abe, H; Aizawa, R; Aizawa, Y; Kitahara, T; Kubo, Y; Matsuoka, M; Tajiri, H; Takakura, K; Yoshizawa, K | 1 |
Chao, Y; Kuo, SC; Lee, KC; Lee, RC; Li, AF; Li, CP; Luo, JC; Wu, CW | 1 |
Bilgrami, SF; Pazooki, M; Usmani, S | 1 |
Fujita, H; Matono, S; Murata, K; Nagano, T; Nishimura, K; Shirouzu, K; Tanaka, T; Yamana, H | 1 |
He, J; Song, Y; Wang, JW; Wang, LH; Wu, LY | 1 |
Atsumi, K; Hirata, H; Honda, H; Isoyama, Y; Matsuura, S; Nomoto, S; Nonoshita, T; Ohga, S; Onishi, K; Shioyama, Y; Terashima, K | 1 |
Chu, Z; Huang, L; Huang, R; Jiang, J; Liang, X; Zhan, Q; Zhou, X | 1 |
Batum, O; Emin Erbaycu, A; Gunduz, A; Tuksavul, F; Zeki Guclu, S; Zeren Ucar, Z | 1 |
Chan, JK; Chen, LM; Cohen, JG; Kapp, DS; Osann, K; Sherman, AE; Shin, JY; Urban, R | 1 |
Bernard, S; Chiu, M; Davies, JM; Dees, EC; Dhruva, NS; Hayes, DN; Hilbun, LR; Ivanova, A; Keller, K; Kim, WY; Socinski, MA; Stinchcombe, TE; Walko, CM | 1 |
Gruellich, C; Hasskarl, J; Schroettner, P; Waller, CF | 1 |
Bamberg, M; Eckert, F; Fehm, T; Müller, AC | 1 |
Davis, D; Guha, S; Richards, D; Yan, P | 1 |
Cantor, A; Miley, D; Reddy, V; Robert, F; Rossman, J | 1 |
Aguero, EG; Garrett-Mayer, E; Sharma, AK; Sherman, CA; Shirai, K; Silvestri, GA; Wahlquist, AE; Watkins, JM; Zauls, AJ | 1 |
Bell, MC; Muirhead, DM; Nelsen, LL | 1 |
Peng, XS; Qin, BF; Wei, Q; Zhou, FX; Zhou, ZT; Zou, LY | 1 |
Brammer, JE; Lulla, P; Lynch, GR | 1 |
Futagami, M; Mizunuma, H; Yokoyama, Y | 1 |
Descourt, R; Noel-Savina, E; Paleiron, N; Quéré, G; Tromeur, C | 1 |
Barbera, S; Barletta, E; Ceribelli, A; De Maio, E; Di Maio, M; Favaretto, A; Filipazzi, V; Gallo, C; Gamucci, T; Gridelli, C; Iaffaioli, RV; Isa, L; Maione, P; Morabito, A; Perrone, F; Piccirillo, MC; Rocco, G; Rossi, A; Signoriello, S; Vecchione, A | 1 |
Ayyathurai, R; Kanagarajah, P; Manoharan, M; Saleem, U | 1 |
Cufer, T; Kern, I; Knez, L; Ovčariček, T; Sadikov, A; Sodja, E | 1 |
Chan, JK; Cohen, JG; Kapp, DS | 1 |
Matsunaga, M; Miwa, K; Noguchi, T; Sasaki, Y | 1 |
Ktenidis, K; Papanikolaou, A; Pervana, S; Tsolakidis, D | 1 |
Di Maio, M; Martelli, O; Rossi, A | 1 |
Du, XH; Mao, WM; Wang, SY; Xu, YP; Zhang, SZ | 1 |
Spigel, DR | 1 |
Ito, K; Kaiho-Sakuma, M; Kurosawa, H; Nagai, T; Nagase, S; Niikura, H; Otsuki, T; Takano, T; Tanaka, S; Tokunaga, H; Toyoshima, M; Utsunomiya, H; Yaegashi, N; Yoshinaga, K | 1 |
Daliani, DD; Logothetis, CJ; Papandreou, CN; Reyes, A; Thall, PF; Troncoso, P; Tu, SM; Wang, X | 1 |
Ding, L; Lang, W; Wang, H; Xiao, L | 1 |
Arance, A; Ashcroft, L; Burgers, JA; Hodgetts, J; Lomax, L; Thatcher, N | 1 |
Brown, JM; Peters, KB | 1 |
Chak, K; Chan, AT; Johnson, P; Lee, TW; Leung, TW; Mok, TS; Wong, H; Yeo, W; Yim, A; Yu, KH; Zee, B | 1 |
Ekedahl, J; Grigoriev, MY; Joseph, B; Lewensohn, R; Magnusson, C; Müller, M; Zhivotovsky, B | 1 |
Ellis, PA; Galani, E; Harper, PG | 1 |
Ardizzoni, A; Biesma, B; Buchholz, E; Burghouts, J; Debruyne, C; Dziadziuszko, R; Gans, S; Giaccone, G; Karnicka-Mlodkowska, H; Legrand, C; Manegold, C; Postmus, PE; Tjan-Heijnen, VC; Van Meerbeeck, JP | 1 |
Asai, M; Iwahori, K; Komuta, K; Kouga, K; Minami, S; Nishiyama, A | 1 |
Agelidou, M; Ferdoutsis, E; Georgoulias, V; Kalbakis, K; Kouroussis, Ch; Magkanas, E; Mavroudis, D; Samonis, G; Souglakos, J; Toumbis, M; Tselepatiotis, E; Tzanakis, N; Veslemes, M; Ziotopoulos, P | 1 |
Berdel, WE; Dölken, G; Kienast, J; Klinke, F; Macha, H; Mohr, M; Oelmann, E; Schmidt, EW; Serve, H; Thomas, M; Zühlsdorf, M | 1 |
Bisset, D; Jaehde, U; Kloft, C; McLeod, HL; Nicolson, MC; Reid, M; Reif, S | 1 |
Buyukberber, S; Camci, C; Elbeyli, L; Sari, I; Sivrikoz, C; Tuncozgur, B; Turk, HM | 1 |
Krüger, I; Lindenfelser, R; Scherwitz, P | 1 |
Hagiwara, N; Makino, H; Maruyama, H; Miyashita, M; Nagasawa, S; Nomura, T; Onda, M; Sasajima, K; Tajiri, T; Takubo, K; Tsuchiya, Y; Yamashita, K | 1 |
Berardi, R; Cappelletti, C; Cellerino, R; Latini, L; Lippe, P; Massacesi, C; Mattioli, R | 1 |
Krystal, GW; Litz, J; Sulanke, G | 1 |
Benchekroun, A; Iken, A; Jira, M; Kasmaoui, el H; Nouini, Y; Zannoud, M | 1 |
Johnson, DH | 5 |
Aamdal, S; Aasebø, U; Boye, N; Bremnes, RM; Dahle, R; Hannisdal, E; Hatlevoll, R; Kaasa, S; Skovlund, E; Sundstrøm, S; Vigander, T; Vilsvik, J; Wang, M | 1 |
Gatzemeier, U; Grunwald, F; Hessler, S; Jagos, U; Kaukel, E; Koschel, G; Reck, M; von Pawel, J | 1 |
Agelaki, S; Androulakis, N; Apostolopoulou, F; Blazoyiannakis, G; Georgoulias, V; Kakolyris, S; Kouroussis, Ch; Magkanas, E; Mavroudis, D; Pavlakou, G; Samonis, G; Vardakis, N; Veslemes, M | 1 |
Antón, LM; Constenla, M; Domínguez, S; Dorta, J; Esteban, E; García-Girón, C; Gómez Aldavarí, JL; Gonzalez-Barón, M; Gracia, M; Lacave, AJ; López, E; López, R; Martín, G; Mel, JR; Peláez, I; Rodríguez, R; Sevilla, I; Valladares, M; Vieitez, JM | 1 |
Fietkau, R; Sauer, R | 1 |
Fan, Y; Huang, ZY; Sun, L; Zhang, YP | 1 |
Turrisi, AT | 4 |
Smit, EF | 1 |
Baker, J; Hand, S; Macbeth, FR; Smith, AP | 1 |
Ardizzoni, A; Biesma, B; Buccholz, E; Burghouts, JT; Caleo, S; Crott, R; Debruyne, C; Giaccone, G; Gorlia, T; Manegold, C; Postmus, PE; Tjan-Heijnen, VC | 1 |
Ebert, BL; Niemierko, E; Salgia, R; Shaffer, K | 1 |
Ariganello, O; Cipri, A; Cortesi, E; De Marinis, F; Gamucci, T; Gasperoni, S; Martelli, O; Migliorino, MR; Nelli, F; Paoluzzi, L; Portalone, L | 1 |
Fujita, S; Kitani, K; Morimoto, T; Nakahira, S; Nomura, T; Okuda, H; Shibata, N; Takeda, M; Tanaka, T; Tsujie, M | 1 |
Lachmann, E; Lin, JT | 1 |
Eguchi, K; Goto, K; Hojo, F; Kakinuma, R; Kodama, T; Kubota, K; Kunitoh, H; Matsumoto, T; Nishiwaki, Y; Ohe, Y; Ohmatsu, H; Saijo, N; Sekine, I; Shinkai, T; Tamura, T; Yoshimura, K | 1 |
Joe, H; Lesperance, M; Lim, J; Ludbrook, JJ; MacNeil, MV; Martins, H; Truong, PT; Webber, A | 1 |
Ohtsuka, M; Satoh, H; Sekizawa, K | 1 |
Munck, JN | 1 |
Fukuoka, M; Kudoh, S; Matsui, K; Mori, K; Nakano, T; Negoro, S; Nishiwaki, Y; Noda, K; Ohsaki, Y; Saijo, N; Sekine, I; Yokoyama, A | 1 |
Adachi, W; Amano, J; Hiraguri, M; Kishimoto, K; Koide, N; Miyabayashi, H; Nakamura, T; Terai, N | 1 |
Hansen, LT; Helleday, T; Lundin, C; Petersen, LN; Poulsen, HS; Spang-Thomsen, M; Sørensen, CS | 1 |
Hansen, LT; Helleday, T; Lundin, C; Petersen, LN; Spang-Thomsen, M | 1 |
al Rabi, N; Artibani, W; Dalpiaz, O; Ficarra, V; Galfano, A; Martignoni, G | 1 |
Bauman, MD; Hatfield, AK; Hillman, S; Jett, JR; Kugler, JW; Levitt, R; Mailliard, JA; Marks, RS; Morton, RF | 1 |
Miyamoto, T; Mukai, S; Nakagawa, T; Ryomoto, M; Tanaka, H; Yamamura, M; Yao, H; Yoshioka, Y | 1 |
Coldman, BJ; Fossella, FV; Glisson, BS; Komaki, R; Kurie, JM; Lee, JS; Lu, C; Palmer, JL; Pisters, KM; Shin, DM | 1 |
Bauman, MD; Ebbert, LP; Kugler, JW; Mahoney, MR; Mailliard, JA; Marks, RS; Schaefer, PL; Sloan, JA; Tazelaar, HD; Wiesenfeld, M | 1 |
Snee, MP | 1 |
Fujita, T; Honoki, H; Inomata, M; Kashii, T; Kawagishi, Y; Kobayashi, M; Maruyama, M; Matsui, S; Miwa, T; Oda, H | 1 |
Harada, M; Hiraki, S; Hiraki, Y; Hiyama, J; Kiura, K; Moritaka, T; Segawa, Y; Tabata, M; Takigawa, N; Tanimoto, M; Ueoka, H; Watanabe, Y; Yonei, T | 1 |
Erturk, D; Unsal, M | 1 |
Blumenschein, GR; Fossella, FV; Glisson, BS; Johnson, FM; Komaki, R; Kurie, JM; Papadimitrakopoulou, VA; Peeples, BO; Pisters, KM | 1 |
Chuang, CY; Kao, A; Kuo, TH; Liu, FY; Wang, JJ; Wu, HS | 1 |
Johnson, DH; Laskin, J; Sandler, A | 1 |
Bonnet, R; Deppermann, KM; Gatzemeier, U; Hessler, S; Kaukel, E; Macha, HN; Reck, M; Ulm, K; von Pawel, J | 2 |
Davey, MW; Davey, RA; Locke, VL | 1 |
Aquino-Parsons, C; Hoskins, PJ; Lee, N; Lim, P; Pike, JA; Swenerton, KD; Wong, F | 1 |
Grassin, F; Guigay, J; L'her, P; Le Moulec, S; Margery, J; Vaylet, F | 1 |
Bamberg, M; Jeremic, B; Molls, M; Zimmermann, FB | 1 |
Changlai, SP; Ding, HJ; Hsu, WH; Huang, WT; Kao, A; Tsai, CS | 1 |
Dar, AR; Stitt, LW; Truong, PT; Videtic, GM; Yu, EW | 1 |
Bavieri, M; Cavazza, A; Crinò, L; Facciolongo, N; Longo, L; Marchioni, A; Migaldi, M; Petruzzelli, S; Rossi, G; Tamberi, S | 1 |
Arcaro, A; Downward, J; Lemoine, NR; Lesay, A; Lopes, R; McNeish, IA; Mehmet, H; Ng, BL; Pardo, OE; Seckl, MJ; Tetley, TD; Warne, PH | 1 |
Greco, FA | 1 |
Eckardt, J; Green, M; Thatcher, N | 1 |
Hasinoff, BB; Hofland, KF; Jensen, PB; Langer, SW; Schroeder, PE; Sehested, M | 1 |
Blumenschein, GR; Feng, L; Fossella, FV; Glisson, BS; Johnson, FM; Komaki, R; Kurie, JM; Lee, JJ; Papadimitrakopoulou, VA; Peeples, BO; Pisters, KM | 1 |
Brega-Massone, PP; Cataldo, I; Conti, B; Ferro, F; Lequaglie, C | 1 |
Hazama, K; Katoh, H; Kondoh, S; Suzuki, Y; Takahashi, M; Takahashi, Y; Takano, S; Yoshioka, T | 1 |
Goto, H; Hanibuchi, M; Miki, T; Sone, S; Uehara, H; Yano, S; Zhang, H | 1 |
Dietrich, PY; Kaiser, L; Kurt, AM; Matthes, T; Weber, D | 1 |
Saijo, N | 2 |
Gomi, K; Inoue, A; Kikuchi, T; Maemondo, M; Miki, M; Nukiwa, T; Saijo, Y; Sato, T; Suzuki, T | 1 |
Chansky, K; Crowley, J; Edelman, MJ; Gandara, DR; Gaspar, LE; Leigh, B; Livingston, R; Taylor, SA; Weiss, GR | 1 |
Hammerschmidt, S; Pohlink, C; Rother, T; Wirtz, H | 1 |
Antoch, G; Debatin, JF; Gutzeit, A | 1 |
Braig, G; Brueck, M; Kramer, W; Vogel, S; Waeger, S | 1 |
Azevedo, CH; Fernandes, DC; Lo Prete, AC; Maranhão, RC; Rodrigues, DG; Valduga, CJ | 1 |
Bartling, B; Lewensohn, R; Michod, D; Widmann, C; Yang, JY; Zhivotovsky, B | 1 |
Ahn, YC; Im, YH; Jung, CW; Kang, WK; Kim, HJ; Kim, K; Kim, WS; Lee, KE; Lee, MH; Lee, SH; Lee, SI; Lim, DH; Nam, E; Park, J; Park, JO; Park, K; Park, SH | 1 |
Edelman, MJ; Hoffman, PC; Karnauskas, R; Kozloff, M; Rudin, CM; Szeto, L; Tomek, R; Vokes, EE | 1 |
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Dahrouge, S; Evans, WK; Goss, G; Logan, DM; Maroun, JA; Martins, H; Radwi, A; Stewart, DJ; Tomiak, E | 1 |
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Anderson, H; Bleehen, NM; Girling, DJ; Lallemand, G; Machin, D; Stephens, RJ; Thatcher, N | 1 |
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de Campos, E; Dougal, M; Milroy, R; Radford, J; Steward, W; Swindell, R; Testa, N; Thatcher, N | 1 |
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Broxterman, HJ; de Vries, EG; Kuiper, CM; Mulder, NH; Scheper, RJ; Versantvoort, CH; Withoff, S | 1 |
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Ettinger, DS; Finkelstein, DM; Johnson, DH; Sarma, RP | 1 |
Belani, CP; Greco, FA; Hainsworth, JD; Levitan, N; Randolph, J; Schacter, LP; Seyedsadr, MS; Wampler, GL | 1 |
Engelholm, SA; Jensen, PB; Petersen, LN; Spang-Thomsen, M; Sørensen, BS | 1 |
Ihde, DC | 1 |
Bacchi, M; Bernhard, J; Cerny, T; Hürny, C; Joss, RA; Leyvraz, S; Martinelli, G; Senn, HJ; Siegenthaler, P; Stahel, R | 1 |
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Gromova, II; Razin, SV; Thomsen, B | 1 |
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Bitran, JD; Green, M; Herndon, JE; Hollis, DR; Perry, M | 1 |
Burt, P; Hicks, F; Leahy, B; Lorigan, P; Prendiville, J; Stout, R; Thatcher, N | 1 |
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Horikawa, S; Katagami, N; Kobayashi, H; Maekawa, N; Matsumoto, H; Matsunaga, K; Nishiyama, H; Okazaki, M; Sugita, T; Suzuki, Y | 1 |
Bleehen, NM; Falk, SJ; Gottlieb, T; Osborne, RJ; Smith, PJ; Souès, S; Watson, JV | 1 |
Fujita, N; Goto, H; Inaba, T; Moriguchi, T; Seto, M; Shimazaki, C; Tatsumi, T; Ueda, R; Yamagata, N; Yamamoto, K | 1 |
Kanzawa, F; Kondo, H; Nishio, K; Saijo, N; Saito, S | 1 |
Deigert, FA; Eagan, RT; Jett, JR; Maksymiuk, AW; Shaw, EG; Su, JQ | 1 |
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Cuffie, C; Fisher, RI; Hamm, J; Kaiser, G; Oken, M; Schiller, JH; Shepherd, F | 1 |
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Cole, SP; Danks, MK; Evans, CD; Mirski, SE | 1 |
Gemba, K; Hiraki, S; Hiyama, J; Kamei, H; Kimura, I; Miyatake, K; Ohnoshi, T; Shibayama, T; Tabata, M; Ueoka, H | 1 |
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Ettinger, DS; Gradishar, W; Johnson, DH; Larson, MM; Merkel, D; Schiller, JH | 1 |
Kim, HJ; Kim, HK; Kim, SJ; Lee, DY; Paik, HC | 1 |
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Greco, FA; Hainsworth, JD; Hande, KR; Holzmer, M; Thompson, DS | 1 |
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Kimura, T; Onodera, K; Sato, T | 1 |
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Cheson, BD; Feigal, EG; Phillips, PH | 1 |
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Kirkpatrick, A; Postmus, PE; Smit, EF; Splinter, TA | 1 |
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Harada, T; Jinnai, H; Ohe, T; Saegusa, S; Suzuki, Y; Ueno, N | 1 |
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Fayers, PM; Girling, DJ; Parmar, MK; Qian, W; Sambrook, RJ; Stephens, RJ | 1 |
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Hochstenbag, MM; ten Velde, GP; Twijnstra, A; Wilmink, JT; Wouters, EF | 1 |
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Crosby, L; Dowlati, A; Levitan, N; Makkar, V; Remick, SC | 1 |
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Ponarska, A; Rogala, E; Rogińska, E; Rowińska-Zakrzewska, E; Szopiński, J | 1 |
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Aasebø, U; Bremnes, RM; Sundstrøm, S; Vilsvik, J | 1 |
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Albertini, MR; Becker, BN; Bodvarsson, S; Burlingham, W; Hafez, GR; Kusaka, S; Pintar, T; Sollinger, HW | 1 |
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Krammer, PH; Sartorius, UA | 1 |
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Giaccone, G; Huisman, C; Postmus, PE; Smit, EF | 1 |
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Ardizzoni, A; Postmus, PE; Tjan-Heijnen, VC | 1 |
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Aisner, J; Budman, DR; Perry, M; Propert, K; Strauss, G; Van Echo, DA; Whitacre, MY | 1 |
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Bao, YH | 1 |
Moore, SR; Reinberg, Y; Zhang, G | 1 |
Bergman, B; Sörenson, S; Sullivan, M | 1 |
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Berendsen, HH; Haaxma-Reiche, H; Postmus, PE; Smit, EF | 1 |
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Alpeter, MD; Glisson, BS | 1 |
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Griffin, JP; Miller, AA; Niell, HB; Stewart, CF; Tolley, EA | 1 |
García Arroyo, R; García Gómez, R; González del Val, R; Martínez del Prado, P; Meana García, A; Pérez Manga, G | 1 |
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Loehrer, PJ | 1 |
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Chang, TC; Hsu, JJ; Hsueh, S; Soong, YK | 1 |
Fukuoka, M; Itoh, K; Kudoh, S; Kusunoki, Y; Masuda, N; Matsui, K; Negoro, S; Nishioka, M; Takifugi, N; Tanaka, H | 1 |
Harrell, JH; Miller, KL | 1 |
Fukuoka, M; Furuse, K; Masuda, N | 1 |
Smith, IE | 1 |
Kennedy, A; Khansur, T | 1 |
de Vries, EG; Meijer, C; Mulder, NH; Mulder, PO; Nanninga, AG; Uges, DR; van der Graaf, WT; Vellenga, E | 1 |
Enokibori, T; Kato, H; Katsura, A; Mori, A; Watanabe, K | 1 |
Arimoto, T; Asakawa, M; Fujikane, T; Kawakami, Y; Miyamoto, H; Nakabayashi, T; Onodera, S; Shimizu, T; Suzuki, A; Yasuda, S | 1 |
Ash, CM; Geddes, D; Goldman, J; Harper, PG; Souhami, RL; Spiro, SG; Tobias, JS; Twelves, CJ | 1 |
Ball, D; Bishop, J; Bull, C; Duval, P; Laidlaw, C; Matthews, J; Ngan, S | 1 |
Fukuoka, M; Furuse, K; Ikegami, H; Nishiwaki, Y; Saijo, N; Shimoyama, M; Suemasu, K; Tamura, T | 1 |
Becker, H; Drings, P; Flechtner, H; Hans, K; Heim, M; Hruska, D; Mende, S; Pritsch, M; Schroeder, M; Wolf, M | 1 |
Eguchi, K; Goya, T; Kojima, A; Kondou, H; Ohe, Y; Saijo, N; Sasaki, Y; Shinkai, T; Tamura, T; Yamada, K | 1 |
Ahlgren, JD; Ellison, NM; Fryer, JG; Heim, WJ; Wampler, GL | 1 |
Burt, P; Prendiville, J; Radford, J; Ranson, M; Steward, W; Stout, R; Thatcher, N | 1 |
Cherryman, G; Hoskin, PJ; Parton, D; Smith, IE; Yarnold, JR | 1 |
Furuse, K | 2 |
Hooi, LM; Iredale, JP; Kerr, KM; Sudlow, MF; Wathen, CG | 1 |
Bergman, B; Bork, E; Dombernowsky, P; Ersbøll, J; Hansen, HH; Hansen, M | 1 |
Fairey, R; Goddard, K; Grafton, C; Karsai, H; Murray, N; Osoba, D; Page, R; Shah, A; Voss, N | 1 |
Ash, CM; Earl, HM; Eraut, D; Geddes, DM; Harper, PG; James, LE; Law, CS; Rudd, RM; Spiro, SG; Tobias, JS | 1 |
Hirata, Y; Mitsugi, K; Mori, T; Nakano, S; Niho, Y; Otuka, T; Tamari, Y; Tsuda, Y | 1 |
de Jong, S; de Vries, EG; Mulder, NH; Zijlstra, JG | 2 |
Levine, PA; Tabbara, IA | 1 |
Ellerbroek, NA; Glisson, BS; Holoye, PY; Hong, WK; Komaki, R; Pang, AC; Roth, JA; Ryan, MB; Zatopek, NK | 1 |
Achterrath, W; Drings, P; Goerg, C; Havemann, K; Tessen, HW; Wolf, M | 1 |
Ehrlich, L; Goldberg, GL; Jones, JG; O'Hanlan, KA; Rodriguez-Rodriguez, L; Runowicz, CD | 1 |
Ikeda, S; Ishida, H; Kado, M; Kusume, K; Matsubara, Y; Matsui, Y; Ohshima, S; Satake, N; Yamamoto, Y | 1 |
Angeletti, CA; Balbarini, A; Del Tacca, M; Macchiarini, P; Mariani, M; Mariotti, R; Mengozzi, G; Palagi, C; Petronio, AS; Squartini, F | 1 |
Aoki, Y; Hiura, K; Katoh, O; Kuroki, S; Yamada, H | 1 |
Fujisue, M; Fukuoka, M; Kudoh, S; Kusunoki, Y; Masuda, N; Matsui, K; Morino, H; Nakagawa, K; Negoro, S; Takifuji, N | 1 |
Atikachai, B; Jiemsripong, K; Phothirat, C; Thongprasert, S | 1 |
Anderson, H; Prendiville, J; Radford, JA; Swindell, R; Thatcher, N | 1 |
Bellmunt, J; Bodi, R; Jolis, L; Mur, E; Navarro, M; Rubio, D; Solé, LA | 1 |
Airoma, G; Bianco, AR; Contegiacomo, A; De Placido, S; Ferrante, G; Gentile, M; Gridelli, C; Lauria, R; Perrone, F | 1 |
Horio, Y; Minami, H; Saka, H; Sakai, S; Shimokata, K | 1 |
Chanda, ER; Cole, SP; Dicke, FP; Gerlach, JH; Mirski, SE | 1 |
Prins, E; Splinter, TA; Van Der Gaast, A; Verwey, J | 1 |
Fukuoka, M; Ito, K; Kudoh, S; Masuda, N; Matsui, K; Negoro, S; Ryu, S; Sakai, N; Takada, M; Takifuji, N | 1 |
Dimbeck, H; Schmoll, HJ; Vallée, D; von Pawel, J; Wilke, H | 1 |
Fukuoka, M; Kudo, S; Masuda, N; Negoro, S; Takada, M | 1 |
Brambilla, C; Brambilla, E; Brichon, PY; Gazzeri, S; Jacrot, M; Morel, F; Moro, D; Nagy-Mignotte, H | 1 |
Crawford, J; Grous, J; Johnson, D; Kris, M; Lyman, G; Ozer, H; Picozzi, V; Rausch, G; Stoller, R; Tabbara, I | 1 |
DeConti, RC; Johnson, DH; Kallas, GJ; Keller, JH; Lee, J; Lyman, GH; Macdonald, J; Patterson, WP; Ringenberg, QS; Ruckdeschel, JC | 1 |
Ishikawa, S; Kawaji, K; Mukai, J; Ogura, T; Okubo, A; Sano, T; Shimizu, E; Tani, K; Yamashita, T | 1 |
Ash, CM; Earl, HM; Harper, PG; James, L; Miles, DW; Rudd, R; Souhami, RL; Spiro, SG; Tobias, JS; Trask, CW | 1 |
Einhorn, LH | 4 |
Fujii, S; Masakane, I | 1 |
Armstrong, JG; Fass, DE; Kris, MG; Rosenstein, MM; Scher, HI; Zelefsky, MJ | 1 |
Albain, K; Crowley, J; Goodman, GE; Livingston, RB; McCulloch, JH; Rivkin, SE | 1 |
Coldman, AJ; Klasa, RJ; Murray, N | 1 |
Evans, WK; Feld, R; Ginsberg, RJ; Johansen, E; Shepherd, FA | 1 |
Dombernowsky, P; Hansen, HH; Hansen, M; Hirsch, FR; Osterlind, K; Pedersen, AG; Sörenson, S | 1 |
Adachi, N; Fujii, T; Haraguchi, M; Komatsu, T; Kurihara, N; Nakaoka, Y; Ota, K | 1 |
Abratt, RP; de Groot, M; Goodman, HT; Jansen, ER; Salton, DG; Willcox, PA | 1 |
Angeletti, CA; Basolo, F; Bruno, J; Hardin, M; Macchiarini, P | 1 |
Morgan, SA; Smith, PJ; Watson, JV | 1 |
Berendsen, HH; Postmus, PE; Sleyfer, DT; Smit, EF | 1 |
Anderson, G; Bowen, DR; Chappell, G; Smith, AP | 1 |
Clancy, L; Daly, P; Kelly, P; O'Brien, AA | 1 |
Asamoto, H; Fujii, H; Kawaguchi, H; Kawakami, A; Ozawa, Y; Sawano, T; Tsutsumi, T | 1 |
Bessonnat, JF; Brune, J; Gharib, C; Ploton, C; Sassolas, G; Trillet, V; Yoanidis, I | 1 |
Ebe, T; Hatakeyama, S; Kohmura, K | 1 |
Greifenberg, B; Kaukel, E; Koschel, G; Patzer, DC | 1 |
Arnaud, A; Balmes, P; Bonnaud, F; Kleisbauer, JP; Poirier, R; Targhetta, R; Taytard, A; Thomas, P; Touron, D; Vergeret, J | 1 |
Gazdar, AF; Ihde, DC; Kadoyama, C; Tsai, CM; Venzon, D | 1 |
Bureau, G; Dabouis, G; Klastersky, J; Lecomte, J; Libert, P; Michel, J; Ravez, P; Sculier, JP; Thiriaux, J; Vandermoten, G | 1 |
Andersen, M; Hansen, HH; Kristjansen, PE | 1 |
Fujiwara, Y; Kanzawa, F; Minato, K; Nakagawa, K; Nishio, K; Saijo, N | 1 |
Comis, RL; Graziano, SL; Green, M; Hayes, DM; Lee, K; Propert, KJ; Tinsley, R | 1 |
Brunk, SF; Dalton, RJ; Everson, L; Jett, JR; Krook, JE; Mailliard, JA; Marschke, RF; Therneau, TM; Twito, DI; Veeder, MH | 1 |
Beck, TM; Blasko, JC; Bukowski, RM; Crowley, JJ; Demattia, MD; Goodman, GE; Livingston, RB | 1 |
Amino, Y; Asada, Y; Fujita, J; Irino, S; Kobayashi, M; Nagai, M; Takigawa, K; Wakana, M | 1 |
Ash, CM; Earl, HM; Geddes, DM; Harper, PG; Quinn, H; Souhami, RL; Spiro, SG; Tobias, JS; Twelves, CJ | 1 |
Coltman, CA; Crowley, JJ; Epstein, RB; Kim, PN; Neilan, B; O'Bryan, RM; Pazdur, R; Stuckey, WJ | 1 |
Abeloff, MD; Aisner, SC; Eggleston, JC; Ettinger, DS; Finkelstein, DM; Ruckdeschel, JC | 1 |
Binaschi, M; Capranico, G; De Isabella, P; Mariani, M; Supino, R; Tinelli, S; Zunino, F | 1 |
Einhorn, LH; McClean, J; Pennington, K | 1 |
Lind, M; Thatcher, N | 1 |
Berendsen, HH; Carney, DN; Grogan, L; Harford, P; Postmus, PE; Smit, EF | 1 |
Greco, FA; Hainsworth, JD; Johnson, DH | 1 |
Miller, AA; Stewart, CF; Tolley, EA | 1 |
Ball, D; Bishop, JF; Bull, C; Friedlander, M; Kefford, R; Olver, IN; Raghavan, D; Stuart-Harris, R; Yuen, K; Zalcberg, J | 1 |
Asakawa, M; Fujita, A; Honda, R; Inoue, Y; Ohshima, S; Suzuki, A; Tagaki, S | 1 |
Asamoto, H; Fujii, H; Kawakami, A; Ozawa, Y; Tsutsumi, T | 1 |
Kajanti, M; Mattson, K; Niiranen, A; Tammilehto, L | 1 |
Creger, RJ; Lazarus, HM; Spitzer, TR | 1 |
Anderson, H; Carroll, KB; Lind, MJ; Swindell, R; Thatcher, N; Woodcock, A | 1 |
Baker, LH; Crowley, JJ; Giri, PG; Gordon, W; Janaki, LM; Kuebler, JP; Mansouri, A; McCracken, JD; Taylor, SA; Weiss, GB | 1 |
Ashley, SA; Ford, HT; Forgeson, GV; Perren, TJ; Smith, IE; Woodiwiss, J; Yarnold, JR | 1 |
Demant, EJ; Hansen, HH; Jensen, PB; Jensen, PS; Sehested, M; Sørensen, BS; Vindeløv, L | 1 |
Bernard, JP; Brune, J; Champel, F; Chauvin, F; Clavel, M; Cordier, JF; Emonot, A; Guérin, JC; Kalb, JC; Trillet, V | 1 |
Leung, WT; Pang, JC; Shiu, WC | 1 |
Horiguchi, T; Kawahara, S; Kiura, K; Mima, Y; Moritaka, T; Nishii, K; Numata, T; Ohnoshi, T; Ueoka, H; Yonei, T | 1 |
Gatzemeier, U; Heckmayr, M; Hossfeld, DK; Koschel, G; Thies, F; Zschaber, R | 1 |
Eich, F; Emser, W; Sybrecht, GW | 1 |
Achterrath, W; Gatzemeier, U; Heckmayr, M; Hossfeld, DK; Neuhauss, R; Reck, M; Zschaber, R | 1 |
Arnold, A; Figueredo, A; Findlay, B; Goodyear, M; Jones, A; Neville, A; Normandeau, R | 1 |
Blotta, A; Boltri, B; Busutti, L; Casadio, M; Falcone, F; Giordani, S; Lelli, G; Pannuti, F; Ramini, R | 1 |
Chasen, MR; Falkson, G; Falkson, HC | 1 |
Cellerino, R; Dazzi, C; Guidi, F; Isidori, P; Rossi, A; Torresi, U; Tummarello, D | 1 |
Jakobsson, M; Järvinen, M; Liippo, K; Nikkanen, V; Nordman, E; Ojala, A; Paloheimo, S | 1 |
Bronchud, MH; Kamthan, AG; Lind, MJ; Ranson, MR; Steward, WP; Stout, R; Thatcher, N | 1 |
Cheson, BD | 1 |
Ando, T; Hao, K; Miyashita, M; Onda, M; Sasajima, K; Takubo, K; Watanabe, M; Yamashita, K | 1 |
Slevin, ML | 1 |
Greco, FA; Hainsworth, JD; Hande, KR; Johnson, DH; Strupp, J | 1 |
Benedetto, P; Feun, LG; Hussein, AM; Otrakji, CL; Sridhar, KS; Waldman, S | 1 |
Doyle, LA; Goldstein, LH; Hamburger, AW; Park, HJ | 1 |
Angeletti, CA; Chella, A; Macchiarini, P; Mengozzi, G; Riva, A; Silvano, G; Solfanelli, S | 1 |
Arriagada, R; Baldeyrou, P; Cerrina, ML; Chomy, P; De Cremoux, H; le Chevalier, T; Martin, M; Pellae-Cosset, B; Ruffie, P; Tarayre, M | 1 |
Choi, NC | 1 |
Glover, DJ; Turrisi, AT | 1 |
Ardizzoni, A; Baldini, E; Corcione, A; Ferrarini, M; Intra, E; Mazzanti, P; Pennucci, MC; Pistoia, V; Rosso, R; Sertoli, MR | 1 |
Bielat, K; Castillo, NB; Lele, SB; Patsner, B; Piver, MS; Tsukada, Y | 1 |
Ito, M | 1 |
Cole, SP; Gerlach, JH; Mirski, SE | 1 |
Dombrowski, H; Drings, P; Hans, K; Harms, V; Havemann, K; Holle, R; Victor, N; Wolf, M | 1 |
Alton, NK; Bronchud, M; Crowther, D; Dexter, TM; Scarffe, JH; Souza, LM; Testa, NG; Thatcher, N | 1 |
Herbst, AL; Senekjian, EK; Talerman, A; Weiser, PA | 1 |
Carney, DN; Harford, P; Postmus, PE; Sleijfer, DT; Smit, EF | 1 |
Bisagni, G; Boni, C; Ceci, G; Cocconi, G; Peracchia, G | 1 |
Hasegawa, K; Hino, M; Kobayashi, K; Kurane, S; Niitani, H; Tuboi, E; Yamano, Y; Yano, T | 1 |
Postmus, PE; Sleijfer, DT; Smit, EF | 1 |
Comis, R; Goodlow, J; Hong, WK; Hurtubise, M; Lanzotti, V; Lawson, R; Luedke, D; Maroun, JA; Nicaise, C; Speer, J | 1 |
Haaxma-Reiche, H; Kirkpatrick, A; Kleisbauer, JP; McVie, JG; Postmus, PE; Sleijfer, DT | 1 |
Berendsen, HH; Haaxma-Reiche, H; Postmus, PE; Sleijfer, DT | 1 |
Becker, H; Drings, P; Flechtner, H; Goerg, R; Hans, K; Havemann, K; Holle, R; Schroeder, M; Wolf, M | 1 |
Bibby, RJ; Edge, JR; Horsfield, N; Johnson, CE; McIllmurray, MB; O'Reilly, JF; Ormerod, LP; Taylor, BE; Willey, RF; Wolstenholme, RJ | 1 |
Jett, JR; Krook, JE; Little, C | 1 |
Ash, CM; Eraut, D; Geddes, DM; Harper, PG; Partridge, M; Quinn, H; Souhami, RL; Spiro, SG; Tobias, JS | 1 |
Alciato, P; Cantone, PA; Fico, D; Gagliardini, R; Petrella, V | 1 |
Hiraki, S; Kawahara, S; Kiura, K; Kozuka, A; Nishii, K; Numata, T; Ohnoshi, T; Ueoka, H; Yamashta, H; Yonei, T | 1 |
Collins, C; Griffin, BR; Higano, CS; Keppen, MD; Livingston, RB; Miller, TP | 1 |
Hiraki, S; Kawahara, S; Kiura, K; Moritaka, T; Nishii, K; Numata, T; Ohnoshi, T; Ueoka, H; Yamashita, H; Yonei, T | 1 |
Bungo, M; Fujita, J; Futami, H; Hashimoto, Y; Hata, Y; Irino, S; Iuchi, Y; Kamei, M; Nakamura, H; Yamaji, Y | 1 |
Ash, CM; Earl, HM; Geddes, DM; Harper, PG; Morittu, L; Souhami, RL; Spiro, SG; Tobias, JS | 1 |
Banham, SW; Milroy, R; Shapiro, D; Shenkin, A | 1 |
Dhingra, HM; Glisson, BS; Holoye, PY; Hong, WK; Lee, JS; Murphy, WK | 1 |
Gazdar, AF; Ihde, DC; Linnoila, RI; Oie, HK; Russell, EK; Steinberg, SM; Stevenson, HC | 1 |
Granger, E; Hammer, BD; Negron, FJ; Paglen, PG; Spaide, RF | 1 |
Ihde, DC; Viallet, J | 1 |
Chahinian, AP; Comis, RL; Hirsh, V; Holland, JF; Kopel, S; Perry, MC; Propert, KJ; Skarin, A; Ware, JH; Zimmer, B | 1 |
Cullinan, SA; Dalton, RJ; Everson, LK; Gerstner, JB; Jett, JR; Krook, JE; Mailliard, JA; Morton, RF; O'Fallon, JR; Tschetter, LK | 1 |
Ash, CM; Earl, HM; Geddes, DM; Goldstone, AH; Hajichristou, HT; Harper, PG; Miles, DW; Souhami, RL; Spiro, SG; Tobias, JS | 1 |
Benfield, GF; Collins, FJ; Cullen, MH; Matthews, HR; Watson, DC | 1 |
Abrams, J; Aisner, J | 1 |
Cerny, T; Lind, M; Stout, R; Swindell, R; Thatcher, N | 1 |
Clark, PI; Gregory, WM; Joel, SP; Lowe, DG; Malik, S; Osborne, RJ; Reznek, RH; Slevin, ML; Wrigley, PF | 1 |
Davis, MP; Minton, JP; Murthy, MS; Simon, J; Wise, H | 1 |
Ohnoshi, T | 1 |
Arriagada, R; de Cremoux, H; de The, H; Dewar, J; Duroux, P; Le Chevalier, T; Martin, M; Ruffie, P; Sancho-Garnier, H; Thomas, F | 1 |
Amadori, D; Ardizzone, A; Cruciani, G; Fiorentini, G; Leoni, M; Marangolo, M; Ravaioli, A; Rosti, G; Sebastiani, L; Tienghi, A | 1 |
Kelsen, DP; Nichols, GL | 1 |
Della Valentina, M; Errante, D; Figoli, F; Magri, MD; Monfardini, S; Talamini, R; Trovo, MG; Veronesi, A; Zagonel, V | 1 |
Kawano, Y; Mukai, J; Nakamura, Y; Nakanishi, M; Ogura, T; Shimizu, E; Sone, S; Takaue, Y; Watanabe, T | 1 |
Campbell, C; Carroll, KB; Lind, M; Moussalli, H; Payne, C; Stout, R; Thatcher, N | 1 |
Bruckner, HW; Morant, R | 1 |
Adachi, M; Fujii, S; Nakajima, K; Sugai, Y; Ueno, K | 1 |
Borges, M; Doyle, LA; Giangiulo, D; Hussain, A; Park, HJ; Yen, RW | 1 |
Alberti, W; Budach, V; Eberhardt, W; Hirche, H; Niederle, N; Schmidt, CG; Schütte, J; Seeber, S | 1 |
Beauduin, M; Bosly, A; Delaunois, L; Duprez, P; Francis, C; Gailly, C; Humblet, Y; Machiels, J; Majois, F; Weynants, P | 1 |
Errington, RD; Green, JA; Hardman, PD; Myint, S; Warenius, HM | 1 |
Bagshawe, KD; Begent, RH; Crawford, SM; Glaser, MG; Newlands, ES; Parker, D; Rustin, GJ; Southcott, BM; Ward, AJ | 1 |
Carney, DN; Grogan, L; Harford, P; Kearns, F | 1 |
Janic, G; Jassem, J; Karnicka-Młodkowska, H; Roszkowski, K; Rowińska-Zakrzewska, E; Szczepek, B; Traczyk, K; Zych, J | 1 |
McVie, G; Muggia, FM | 1 |
Clark, DA; Coy, P; Evans, WK; Feld, R; Levitt, M; MacDonald, A; Murray, N; Osoba, D; Shepherd, FA; Willan, A | 1 |
Evans, WK; Feld, R; MacCormick, R; Shepherd, FA; Yau, JC | 1 |
Fletcher, J; Gilson, D; Morgan, DA | 1 |
Lankelma, J; Pinedo, HM; Stam, J; van Hoogenhuijze, J | 1 |
Aroney, R; Bishop, JF; Gianoutsos, P; Kefford, R; Lee, J; Morstyn, G; Olver, IN; Raghavan, D; Stuart-Harris, R; Yuen, K | 1 |
Buchanan, R; Herbert, A; Jefferys, M; Lea, R; McMillan, I; Mead, G; Sweetenham, J; Thompson, J; Whitehouse, JM; Williams, CJ | 1 |
Bitran, JD; Hoffman, PC; Kaminer, LS; Larson, RA; Le Beau, MM; Purl, S; Ratain, MJ; Skosey, C; Vardiman, JW; Wade, J | 1 |
Anderson, H; Barber, PV; Barnes, P; Cerny, T; Deiraniya, A; Stout, R; Thatcher, N; Wolstenholme, RJ | 1 |
Kajisa, T; Shimazu, H; Tanabe, G; Yoshida, A | 1 |
Chikata, E; Hara, K; Ito, F; Kado, M; Kanda, T; Matsui, Y; Nakayama, M; Oshima, S; Sakai, S; Shimokata, K | 1 |
Bai, L; Feng, FY; Qiu, Q; Song, SZ; Sun, Y; Wang, JW; Wang, QL; Yin, WB; Zhou, JC | 1 |
Bakker, W; Berendsen, HH; Burghouts, JT; Postmus, PE; Splinter, TA; van Zandwijk, N | 1 |
Carey, RW; Choi, N; Green, M; Kwiatkowski, DJ; Propert, KJ | 1 |
Dommes, M; Drings, P; Gropp, C; Hans, K; Havemann, K; Heim, M; Holle, R; Mende, S; Schroeder, M; Wolf, M | 1 |
Lebeau, B | 1 |
Sculier, JP | 1 |
Arriagada, R; Baume, D; Beaujean, F; Gouyette, A; Hayat, M; Le Chevalier, T; Ostronoff, M; Pico, JL; Rebattu, P | 1 |
Calciati, A; Donadio, M; Ferrati, P; Giaccone, G; Testore, F | 1 |
Coy, P; Evans, WK; Feld, R; Hodson, I; MacDonald, AS; Osoba, D; Pater, JL; Payne, DG | 1 |
Ito, K; Kanamori, K; Kanno, M; Kobayashi, K; Kondo, K; Matsuda, T; Nakamura, S; Nakazumi, Y; Yoshida, T | 1 |
Brincker, H; Hansen, PV; Hindberg, J | 1 |
Farmer, ER; Friedman, KJ; Hood, AF; Yokel, BK | 1 |
Birch, R; Crawford, J; Einhorn, LH; Greco, FA; Johnson, DH; Omura, G | 1 |
Bonomi, P; Lee, MS; Maffey, S; Reddy, S; Rowland, KM; Taylor, SG | 1 |
Bandou, H; Doi, H; Fukuta, K; Kinoshita, S; Matsuura, A; Nakamura, T; Ogura, T; Shimizu, E; Yamasaki, K; Yamashita, T | 1 |
Bozzino, JM; Cantwell, BM; Corris, P; Harris, AL | 1 |
Ardizzoni, A; Bruschi, G; Canobbio, L; Figoli, F; Lo Re, G; Mazza, F; Monfardini, S; Rosso, R; Veronesi, A; Zagonel, V | 1 |
Higuchi, Y; Hisa, S; Hoshi, K; Kimura, K; Moriya, H; Satoh, T; Suzuki, S | 1 |
Cellerino, R; Guidi, F; Isidori, P; Porfiri, E; Raspugli, M; Tummarello, D | 1 |
Engelhardt, R | 1 |
Becquart, D; Klastersky, J; Libert, P; Longeval, E; Ravez, P; Rocmans, P; Sculier, JP; Thiriaux, J; van Houtte, P; Vandermoten, G | 1 |
Baba, M; Kimura, H; Momiki, S; Ogawa, T; Yamaguchi, Y | 1 |
Fukuoka, M; Kusunoki, Y; Masuda, N; Matsui, K; Negoro, S; Ryu, S; Sakai, N; Takada, M; Takifuji, N; Yamamoto, H | 1 |
Glover, DJ; Mason, BA; Turrisi, AT | 2 |
Creagan, ET; Kovach, JS; Richardson, RL | 1 |
Einhorn, LH; Greco, FA; Loehrer, PJ | 1 |
Ishizuka, T; Minato, K; Saito, R; Tsuchiya, S | 1 |
Ashley, SE; Cherryman, G; Glaholm, J; Magrini, S; Repetto, L; Smith, IE; Yarnold, JR | 1 |
Akman, S; Carr, B; Doroshow, J; Leong, L; Margolin, K | 1 |
Banham, SW; Blackie, RB; Cummings, J; Cunningham, D; Kaye, SB; McTaggart, L; Soukop, M | 1 |
Evans, WK; Feld, R; Goodwin, PJ; Pater, J | 1 |
Achterrath, W; Gunzer, U; Lenaz, L; Preusser, P; Schmoll, HJ; Wilke, H | 1 |
Itoh, K; Kokado, Y; Kyakuno, M; Sagawa, S; Sakai, H; Shin, T | 1 |
Ayoub, J; Eisenhauer, E; Evans, WK; Feld, R; Hughes, P; Maroun, JA; Shepherd, FA | 1 |
Beaujean, F; Benard, J; Bettan-Renaud, L; Gavoille, A; Lopez, M; Pico, JL; Riou, G | 1 |
Becker, H; Bülzebruck, H; Djawid, N; Drings, P; Ruchalla, E; Stiefel, P; Tessen, HW | 1 |
Gatzemeier, U; Heilmann, HP; Hossfeld, DK; Kaukel, E; Koschel, G; Zschaber, R | 1 |
Berendsen, HH; Haaxma-Reiche, H; Postmus, PE | 1 |
Green, JA; Tarpey, AW; Warenius, HM | 1 |
Brust, J; Paschke, R; Queisser, W; Worst, P | 1 |
Coy, P; Feld, R; Hodson, I; Payne, D | 1 |
Høst, H; Kaasa, S; Olsnes, BT; Thorud, E | 1 |
Figueredo, AT; Frank, G; Hryniuk, WM; Rendell, S; Strautmanis, I | 1 |
Bazos, MJ; DeBoer, G; Evans, WK; Feld, R; Osoba, D; Shepherd, FA | 1 |
Anderson, PN; Baker, LH; Comis, RL; Daniels, JR; Einhorn, LH; Harvey, HA; Issell, BF; Lanzotti, VA; Lawson, RD; Wampler, GL | 1 |
Greco, FA; Grosh, WW; Hainsworth, JD; Hande, KR; Johnson, DH; Porter, LL; Wolff, SN | 1 |
Carr, DT; Chiuten, DF; Dhingra, HM; Farha, P; Murphy, WK; Spitzer, G; Umsawasdi, T; Valdivieso, M | 1 |
Abeloff, MD; Berkman, AW; Markman, M; Waterfield, WC | 1 |
Abratt, RP; Levin, W | 1 |
Alonso, MT; Leyland-Jones, B; Marsoni, S; O'Dwyer, PJ; Wittes, RE | 1 |
Ahmedzai, S; Banham, S; Burnett, A; Cunningham, D; Dorward, A; Hutcheon, A; Kaye, S; Lucie, N; Soukop, M | 1 |
Greco, FA; Hainsworth, JD; Hande, KR; Johnson, DH; Porter, LL; Wolff, SN | 2 |
Bateman, NT; Bellamy, D; Calman, FM; Costello, J; Farebrother, M; Rubens, RD; Slevin, ML; Timothy, AR | 1 |
Drings, P; Manke, HG | 1 |
Holoye, PY | 1 |
Finkel, H; Grapski, RT; Krikorian, JG; Lopez, JA; Mann, J; Nassif, E; Vannicola, P | 1 |
Becquart, D; Dalesio, O; Dumont, JP; Klastersky, J; Longeval, E; Michel, J; Rocmans, P; Sculier, JP; Vandermoten, G | 1 |
Adelstein, DJ; Hines, JD | 1 |
Greco, FA; Hainsworth, JD; Hande, KR; Johnson, DH; Porter, LL | 1 |
Danigel, H; Dellbrügge, J; Jungclas, H; Pflüger, KH; Schmidt, L | 1 |
Barber, PV; Carroll, KB; Feinmann, D; James, RD; Lawson, BA; Steward, WP; Thatcher, N | 1 |
Cate, CC; Curphey, TJ; Douple, EB; Maurer, LH; Pettengill, OS; Sorenson, GD | 1 |
Bonomi, P; Bunting, N; Creech, RH; O'Reilly, W; Ruckdeschel, JC; Stolbach, L; Vogl, SE | 1 |
Chikata, E; Hara, K; Ito, F; Kado, M; Kanda, T; Matsui, Y; Nakayama, M; Ohshima, S; Sakai, S; Shimokata, K | 1 |
Bassett, H; Carroll, KB; Grötte, G; Smith, DB; Stout, R; Thatcher, N; Winson, M | 1 |
Harvey, VJ; Joel, SP; Johnston, A; Slevin, ML; Wrigley, PF | 2 |
Kimura, K; Niitani, H | 1 |
Ahmedzai, S; Banham, SW; Cunningham, D; Dorward, A; Hutcheon, AH; Kaye, SB; Soukop, M; Stack, BR; Stevenson, RD; Tansey, P | 1 |
Hansen, HH; Hansen, M; Osterlind, K; Pedersen, AG; Pedersen-Bjergaard, J; Philip, P | 1 |
Harvey, VJ; Joel, SP; Johnston, A; Slevin, ML; Smythe, MM; Wrigley, PF | 1 |
Anderson, G; Chappell, AG; James, KW; Littlewood, TJ; Smith, AP | 1 |
Hara, K; Kado, M; Kanda, T; Matsui, Y; Oshima, S; Shima, K; Shimokata, K; Takenaka, S | 1 |
Evans, BD; Smith, IE | 1 |
Coy, P; Fryer, C; Goldie, J; Gudauskas, G; Hadzic, E; Klimo, P; Murray, N; Shah, A; Voss, N; Wilson, K | 1 |
Bakaert, AB; De Broe, ME; Holthuis, JJ; Van de Vyver, FL; van Oort, WJ; Verleun, H | 1 |
Livingston, RB | 1 |
de Vries, EG; de Vries-Hospers, HG; Maas, A; Meinesz, AF; Mulder, NH; Mulder, PO; Postmus, PE; Sleijfer, DT | 1 |
Chak, LY; Cox, RS; Kushlan, PD; Porzig, KJ; Sikic, BI; Wasserstein, P; Zatz, LM | 1 |
Hiraga, Y; Ito, T; Konno, K; Nagahama, F; Nakabayashi, T; Nakai, Y; Oizumi, K; Sato, M; Takebe, K; Tamura, M | 1 |
Peters, W; Souhami, R | 1 |
Kinameri, K; Kurita, Y; Matsuura, N; Sano, K; Yokoyama, A | 1 |
Hara, K; Ikebe, A; Ishizaki, T; Iwasaki, H; Kanda, T; Koteda, T; Nakano, M; Oka, M; Okuno, K; Tsutsumi, T | 1 |
Birch, R; Greco, FA; Sarma, P; Wolff, SN | 1 |
Batist, G; Bunn, PA; Carney, DN; Cowan, KH; Gilliom, M; Ihde, DC; Veach, SR | 1 |
Fukuda, Y; Homma, T; Nakata, M; Noguchi, Y; Yoneda, S; Yoshida, S | 1 |
Colozza, MA; Crinò, L; Davis, S; Grignani, F; Lubansky, K; Tonato, M | 1 |
Brattain, MG; Long, BH; Musial, ST | 1 |
Kerstjens, HA; Lo, GT; Meinesz, AF; Postmus, PE; Sleijfer, DT; Sluiter, HJ | 1 |
Bentley, DP; Littlewood, TJ; Smith, AP | 2 |
Alberto, P; Cavalli, F; Joss, R; Kaplan, S; Martz, G; Mermillod, B; Obrecht, JP | 1 |
Hoshino, T; Kimura, K; Moriya, H; Yaginuma, K | 1 |
Cummings, J; Cunningham, D; Forrest, GJ; McTaggart, L; Soukop, M; Stuart, JF | 1 |
Coy, P; Evans, WK; Feld, R; Hodson, I; Levitt, M; Murray, N; Osoba, D; Pater, J; Shelley, W; Willan, A | 1 |
DeBoer, G; Evans, WK; Feld, R; Osoba, D; Shepherd, FA | 1 |
Band, P; Brown, E; Goldie, J; Kostashuk, E; Laukkanen, E; Murphy, K; Murray, N; Shah, A; Sparling, T; Van den Hoek, J | 1 |
Crowley, J; Giri, PG; Gordon, W; Janaki, LM; McCracken, JD; Taylor, SB; Vance, RB; Weiss, GB | 1 |
Bunn, PA; Einhorn, L; Greco, FA | 1 |
Abrams, J; Aisner, J; Propert, K; Whitacre, M | 1 |
Evans, TL | 1 |
Hayashibe, A; Hino, M; Honda, R; Kitaya, T; Matsuyama, T; Nishiwaki, Y; Yano, H | 1 |
Ahmedzai, S; Banham, SW; Cunningham, D; Dorward, AJ; Gregor, A; Hutcheon, AW; Kaye, SB; Mackay, NS; Soukop, M; Stack, BH | 1 |
Meyer, JA | 1 |
Budd, GT; Coltman, CA; Crowley, JP; Grever, MR; Harker, G; Livingston, RB; Mira, JG; Rivkin, SE; Schulman, S; Vogel, S | 1 |
Dixon, RH; Gottleib, RJ; Harvey, HA; Hoffman, SL; Lipton, A; Messeih, AA; Ricci, JA; Schweitzer, JM; Simmonds, MA; Stryker, JA | 1 |
Díaz-Rubio García, E; González Larriba, JL; Martín Jiménez, M; Sangro Gómez-Acebo, B; Vila Borrajo, C | 1 |
Barkley, HT; Benjamin, RS; Bodey, GP; Frankmann, C; Jeffries, DG; McMurtrey, MJ; Murphy, WK; Valdivieso, M; Welch, SR | 1 |
Ardizzoni, A; Baracco, F; Benvenuto, F; Canobbio, L; Faravelli, B; Nosenzo, M; Pronzato, P; Repetto, L; Serrano, J; Simonassi, C | 1 |
Evans, BD; Ford, HT; Gore, ME; Repetto, L; Smith, IE; Vincent, MD; Yarnold, JR | 1 |
Drings, P; Gropp, C; Hans, K; Havemann, K; Heim, M; Holle, R; Manke, HG; Schroeder, M; Victor, N; Wolf, M | 1 |
Aisner, J; Poplin, E; Thompson, B; Whitacre, M | 1 |
Abel, U; Bülzebruck, H; Drings, P; Kleckow, M; Manke, HG; Stiefel, P | 1 |
Eguchi, K; Nakajima, T; Ochi, H; Saijo, N; Sakurai, M; Sasaki, Y; Shinkai, T; Suemasu, K; Suga, J; Tominaga, K | 1 |
Coles, DT; Creagan, ET; Eagan, RT; Frytak, S; Jett, JL; Lee, RE; Richardson, RL | 1 |
Dombernowsky, P; Hansen, HH; Hansen, M; Hirsch, FR; Osterlind, K; Sørensson, S; Vindeløv, LL | 1 |
Chen, TT; Coltman, CA; Crowley, JJ; Grozea, PN; Kies, MS; Livingston, RB; Mira, JG; Pazdur, R; Rivkin, SE; Ward, JH | 1 |
Creagan, ET; Eagan, RT; Frytak, S; Lee, RE; Richardson, RL; Therneau, TM | 1 |
Green, MR; Luikart, SD; Modeas, CR; Perry, MC; Propert, KJ | 1 |
Buchanan, RB; Mead, GM; Sweetenham, JW; Thompson, J; Whitehouse, JM; Williams, CJ | 1 |
Abeloff, MD; Adelstein, DJ; Baker, RR; Eggleston, JC; Ettinger, DS; McKneally, MF; Ruckdeschel, JD; Woll, J | 1 |
DeLeo, MJ; Greco, FA; Hainsworth, JD; Hande, KR; Johnson, DH; Wolff, SN | 1 |
Neville, AJ; Remick, SC; Willson, JK | 1 |
Balice, A; Basilico, L; Morera, E; Nuzzo, A; Peretti, G; Ursini, LA | 1 |
Dalesio, O; Kirkpatrick, A; McVie, JG; van Zandwijk, N | 1 |
Haaxma-Reiche, H; Kirkpatrick, A; Kleisbauer, JP; Postmus, PE; Sleijfer, DT; ten Velde, G | 1 |
Clamon, GH; Glauber, J | 1 |
Klastersky, J; Sculier, JP | 1 |
Bien, R; Keohane, M; Papac, RJ; Son, Y; Tiedemann, D; Yesner, R | 1 |
Abratt, RP; Hewitson, RH; Willcox, PA | 1 |
Coy, P; Evans, WK; Feld, R; Hodson, I; MacDonald, AS; Osoba, D; Pater, JL; Payne, D; Shelley, W | 1 |
165 review(s) available for etoposide and Carcinoma, Oat Cell
Article | Year |
---|---|
Recent Advances in the Management of Small Cell Carcinoma of the Uterine Cervix.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Neuroendocrine; Carcinoma, Small Cell; Cervix Uteri; Cisplatin; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Neoplasm Staging; Platinum; Rare Diseases; Small Cell Lung Carcinoma; Uterine Cervical Neoplasms | 2023 |
Metastatic Small Cell Carcinoma of a Male Breast: A Case Report and Review of the Literature.
Topics: Breast Neoplasms; Carcinoma, Neuroendocrine; Carcinoma, Small Cell; Etoposide; Humans; Male; Middle Aged; Prognosis | 2023 |
Worsening of anti-Hu paraneoplastic neurological syndrome related to anti-PD-1 treatment: Case report and review of literature.
Topics: Antibodies, Antinuclear; Antibodies, Neoplasm; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Autoantigens; Carboplatin; Carcinoma, Small Cell; Cerebellar Neoplasms; Combined Modality Therapy; Disease Progression; ELAV Proteins; Etoposide; Female; Humans; Lung Neoplasms; Middle Aged; Nivolumab; Paraneoplastic Syndromes, Nervous System; Programmed Cell Death 1 Receptor; Radiotherapy, Adjuvant; Treatment Outcome | 2020 |
Sinonasal inverted papilloma associated with small cell neuroendocrine carcinoma: A case report and literature review of rare malignancies associated with inverted papilloma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Neuroendocrine; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Maxillary Sinus Neoplasms; Nasal Obstruction; Nasal Polyps; Nose Neoplasms; Otorhinolaryngologic Surgical Procedures; Papilloma, Inverted; Radiotherapy, Intensity-Modulated | 2019 |
Neuroendocrine small cell rectal cancer metastasizing to the liver: a unique treatment strategy, case report, and review of the literature.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Carcinoma, Neuroendocrine; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Liver Neoplasms; Male; Middle Aged; Prognosis; Rectal Neoplasms; Review Literature as Topic; Somatostatin; Tomography, X-Ray Computed | 2013 |
Assessing the relative effectiveness and tolerability of treatments in small cell lung cancer: a network meta-analysis.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Epirubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Randomized Controlled Trials as Topic | 2013 |
[Clinical analysis of 17 cases of gastric small cell carcinoma].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Etoposide; Female; Follow-Up Studies; Gastrectomy; Humans; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplastic Cells, Circulating; Retrospective Studies; Stomach Neoplasms; Survival Rate | 2013 |
[Small cell neuroendocrine carcinoma of the uterine cervix: Report of six cases and a review of the literature].
Topics: Adult; Antineoplastic Agents; Carcinoma, Neuroendocrine; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Etoposide; Female; Humans; Hysterectomy; Lymph Node Excision; Middle Aged; Neoplasm Metastasis; Radiotherapy, Adjuvant; Retrospective Studies; Uterine Cervical Neoplasms | 2014 |
Primary small cell neuroendocrine carcinoma of the tonsil: a case report and review of the literature.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Biopsy; Carcinoma, Neuroendocrine; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Immunohistochemistry; Male; Middle Aged; Mitotic Index; Neoplasm Recurrence, Local; Time Factors; Tomography, X-Ray Computed; Tonsillar Neoplasms; Treatment Outcome; Tumor Burden | 2014 |
Accelerated hyperfractionated radiotherapy for small cell carcinoma of the nasopharynx.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chemoradiotherapy; Cisplatin; Dose Fractionation, Radiation; Etoposide; Follow-Up Studies; Humans; Male; Middle Aged; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; Neoplasm Staging; Risk Assessment; Treatment Outcome | 2015 |
[Intravesical Recurrence of Small Cell Carcinoma of the Ureter: A Case Report].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Humans; Male; Middle Aged; Nephrectomy; Recurrence; Ureteral Neoplasms; Urinary Bladder Neoplasms | 2016 |
Carboplatin and etoposide combined with radiotherapy for limited-stage small-cell esophageal carcinoma: three cases and review of the literature.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Esophageal Neoplasms; Etoposide; Female; Humans; Male; Middle Aged; Radiation Injuries | 2010 |
A meta-analysis of randomized controlled trials comparing irinotecan/platinum with etoposide/platinum in patients with previously untreated extensive-stage small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carboplatin; Carcinoma, Small Cell; Cisplatin; Disease-Free Survival; Etoposide; Humans; Irinotecan; Lung Neoplasms; Randomized Controlled Trials as Topic | 2010 |
Small cell carcinoma of the cervix: treatment and survival outcomes of 188 patients.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Etoposide; Female; Humans; Hysterectomy; Kaplan-Meier Estimate; Lymph Node Excision; Lymphatic Metastasis; Middle Aged; Multivariate Analysis; Neoplasm Recurrence, Local; Radiotherapy, Adjuvant; Registries; Uterine Cervical Neoplasms | 2010 |
Unusual case of small cell gastric carcinoma: case report and literature review.
Topics: Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Carboplatin; Carcinoma, Small Cell; Chromogranins; Diabetes Mellitus, Type 2; Endoscopy; Etoposide; Female; Humans; Hypoglycemic Agents; Male; Middle Aged; Prognosis; Stomach Neoplasms; Synaptophysin; Tretoquinol | 2011 |
Small cell carcinoma arising from the bulbar urethra: a case report and literature review.
Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Biopsy; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Immunohistochemistry; Male; Treatment Outcome; Urethra; Urethral Neoplasms | 2012 |
The management of small-cell carcinomas of the gynecologic tract.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Etoposide; Female; Genital Neoplasms, Female; Humans; Molecular Targeted Therapy; Neoplasm Recurrence, Local; Organoplatinum Compounds | 2012 |
Primary ovarian small cell carcinoma of pulmonary type with enlarged paraaortic lymph node masses: a case report and review of the literature.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Carboplatin; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Etoposide; Female; Humans; Lymphatic Metastasis; Middle Aged; Ovarian Neoplasms | 2012 |
Treatment of patients with small-cell lung cancer: from meta-analyses to clinical practice.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Etoposide; Humans; Lung Neoplasms; Meta-Analysis as Topic | 2013 |
Desmoplastic small round cell tumour: a description of two cases and review of the literature.
Topics: Abdominal Neoplasms; Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Fatal Outcome; Humans; Liver Neoplasms; Male; Prognosis; Salvage Therapy | 2003 |
Limited stage small cell lung cancer: treatment and therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Etoposide; Humans; Irinotecan; Lung Neoplasms; Prognosis; Treatment Outcome | 2003 |
[A patient with stage IVb small cell carcinoma of the esophagus who survived 23 months after systemic cancer chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Esophageal Neoplasms; Etoposide; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Staging; Survivors | 2003 |
Lambert-eaton myasthenic syndrome: a case report and review of the literature.
Topics: Aged; Antineoplastic Agents; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Lambert-Eaton Myasthenic Syndrome; Lung Neoplasms; Respiratory Distress Syndrome | 2002 |
Do age and comorbidity impact treatment allocation and outcomes in limited stage small-cell lung cancer? a community-based population analysis.
Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; British Columbia; Carcinoma, Small Cell; Cisplatin; Cohort Studies; Combined Modality Therapy; Comorbidity; Cranial Irradiation; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Life Tables; Lung Neoplasms; Male; Middle Aged; Palliative Care; Patient Selection; Prognosis; Proton Therapy; Radiotherapy, High-Energy; Retrospective Studies; Risk Factors; Survival Analysis; Treatment Outcome; Vincristine | 2003 |
Small cell carcinoma of the bladder: a case report and a literature review.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carboplatin; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cystectomy; Doxorubicin; Etoposide; Fatal Outcome; Humans; Ifosfamide; Life Tables; Liver Neoplasms; Male; Middle Aged; Stevens-Johnson Syndrome; Survival Analysis; Urinary Bladder Neoplasms; Vincristine | 2003 |
An advance in small-cell lung cancer treatment--more or less.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Greece; Humans; Lung Neoplasms; Multicenter Studies as Topic; Paclitaxel; Randomized Controlled Trials as Topic; Survival Analysis; Treatment Outcome; United States; Vincristine | 2003 |
Limited-disease small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Dose Fractionation, Radiation; Etoposide; Humans; Lung Neoplasms; Neoplasm Staging; Prognosis | 2003 |
Progress in treatment of small-cell lung cancer: role of CPT-11.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Etoposide; Female; Humans; Irinotecan; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Topoisomerase I Inhibitors | 2003 |
[Molecular pathogenesis of lung cancers and the preservative therapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Cycle Proteins; Cisplatin; Enzyme Inhibitors; Etoposide; Gefitinib; Gene Targeting; Genes, bcl-2; Genes, p53; Genetic Therapy; Humans; Lung Neoplasms; Mass Screening; Mutation; Paclitaxel; Protein-Tyrosine Kinases; Quinazolines; Radiotherapy, Adjuvant | 2004 |
Chemotherapy of small cell lung cancer: state of the art.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Dose-Response Relationship, Drug; Etoposide; Humans; Ifosfamide; Irinotecan; Lung Neoplasms; Quality of Life; Survival Rate; Treatment Outcome | 2004 |
The impact of dose per cycle of etoposide and cisplatin on outcomes in patients with extensive small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials, Phase II as Topic; Etoposide; Humans; Leukopenia; Lung Neoplasms; Neoplasm Staging; Neutropenia; Randomized Controlled Trials as Topic; Survival Analysis; Thrombocytopenia; Treatment Outcome | 2004 |
Small cell lung cancer: the importance of the extracellular matrix.
Topics: Apoptosis; Carcinoma, Small Cell; Cell Adhesion; Cell Movement; Etoposide; Extracellular Matrix; Fibronectins; Humans; Integrins; Lung Neoplasms | 2004 |
Treatment options for small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzamides; Camptothecin; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Imatinib Mesylate; Irinotecan; Lung Neoplasms; Male; Neoplasm Staging; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Radiotherapy, Adjuvant; Risk Factors; Sex Distribution; Smoking; Survival Rate; Treatment Outcome; United States | 2004 |
[A case of well controlled renal small cell carcinoma with metastasis treated by intensive therapy].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Etoposide; Humans; Kidney Neoplasms; Male; Nephrectomy | 2004 |
Primary small cell neuroendocrine carcinoma of the vagina: a clinicopathologic study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brachytherapy; Carcinoma, Small Cell; Chromogranin A; Chromogranins; Cisplatin; Combined Modality Therapy; Etoposide; Fatal Outcome; Female; Hemorrhage; Humans; Keratins; Middle Aged; Neoplasm Proteins; Nuclear Proteins; Radioisotope Teletherapy; Synaptophysin; Thyroid Nuclear Factor 1; Transcription Factors; Vaginal Diseases; Vaginal Neoplasms | 2004 |
Analysis of treatment for small cell cancer of the bladder and report of three cases.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Biomarkers, Tumor; Bone Neoplasms; Carboplatin; Carcinoma, Small Cell; Carcinoma, Transitional Cell; Cisplatin; Combined Modality Therapy; Cystectomy; Deoxycytidine; Disease Progression; Etoposide; Gemcitabine; Humans; Life Tables; Liver Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Neoplasms, Second Primary; Prostatectomy; Retrospective Studies; Treatment Outcome; Urinary Bladder Neoplasms; Urinary Diversion | 2004 |
In vivo efficacy of STI571 in xenografted human small cell lung cancer alone or combined with chemotherapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzamides; Carcinoma, Small Cell; Cell Proliferation; Etoposide; Humans; Ifosfamide; Imatinib Mesylate; Immunoenzyme Techniques; Lung Neoplasms; Mice; Mice, Nude; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Receptor, Platelet-Derived Growth Factor beta; Topotecan; Transplantation, Heterologous | 2005 |
Combined modality therapy for limited-disease small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Etoposide; Humans; Lung Neoplasms; Prognosis; Radiotherapy, Adjuvant | 2005 |
Lung cancer.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Combined Modality Therapy; Etoposide; Humans; Lung Neoplasms; Palliative Care | 2004 |
Small-cell lung cancer: current therapy and novel agents.
Topics: Adult; Age Factors; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Etoposide; Humans; Irinotecan; Lung Neoplasms; Middle Aged; Neoplasm Staging; Prognosis | 2005 |
[Treatment of small cell lung cancer].
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Dose Fractionation, Radiation; Drug Administration Schedule; Etoposide; Humans; Irinotecan; Lung Neoplasms; Survival Analysis | 2005 |
[A case of granulocyte-colony stimulating factor producing small cell carcinoma of esophagus].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Esophageal Neoplasms; Etoposide; Granulocyte Colony-Stimulating Factor; Humans; Male; Remission Induction | 2005 |
[A case of small cell carcinoma of kidney; solitary splenic metastasis].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Etoposide; Humans; Kidney Neoplasms; Lymph Nodes; Lymphatic Metastasis; Male; Nephrectomy; Splenic Neoplasms | 2005 |
Thoracic radiation therapy for limited-stage small-cell lung cancer: unanswered questions.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Etoposide; Humans; Lung Neoplasms; Neoplasm Staging; Prognosis; Radiation Tolerance | 2005 |
[Chemotherapy for lung cancer patients].
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Docetaxel; Erlotinib Hydrochloride; Etoposide; Evidence-Based Medicine; Gefitinib; Humans; Irinotecan; Lung Neoplasms; Protein Kinase Inhibitors; Quinazolines; Randomized Controlled Trials as Topic; Taxoids | 2006 |
Available treatment options for the management of Lambert-Eaton myasthenic syndrome.
Topics: 4-Aminopyridine; Antineoplastic Agents; Carcinoma, Small Cell; Cholinesterase Inhibitors; Cisplatin; Etoposide; Guanidine; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; Immunotherapy; Lambert-Eaton Myasthenic Syndrome; Lung Neoplasms; Parasympathomimetics; Plasmapheresis; Potassium Channel Blockers; Prednisolone; Pyridostigmine Bromide; Randomized Controlled Trials as Topic | 2006 |
Early compared with late radiotherapy in combined modality treatment for limited disease small-cell lung cancer: a London Lung Cancer Group multicenter randomized clinical trial and meta-analysis.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Cranial Irradiation; Cyclophosphamide; Dose Fractionation, Radiation; Doxorubicin; Etoposide; Female; Humans; London; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Radiotherapy, Adjuvant; Survival Analysis; Time Factors; Treatment Outcome; Vincristine | 2006 |
[Evaluation of clinical practice in pulmonary oncology: a review of the literature].
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Bronchial Neoplasms; Carcinoma, Small Cell; Cisplatin; Cost-Benefit Analysis; Etoposide; France; Humans; Neoplasm Staging; PubMed; Risk Factors; Sex Factors; Socioeconomic Factors; Survival Analysis; Treatment Outcome | 2006 |
[Lung cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Docetaxel; Drug Administration Schedule; Etoposide; Glutamates; Guanine; Humans; Irinotecan; Lung Neoplasms; Pemetrexed; Taxoids | 2007 |
Chemotherapy for relapsed small cell lung cancer: a systematic review and practice guideline.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials, Phase III as Topic; Etoposide; Female; Humans; Infusions, Intravenous; Lomustine; Lung Neoplasms; Male; Maximum Tolerated Dose; Melphalan; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Ontario; Practice Guidelines as Topic; Prognosis; Randomized Controlled Trials as Topic; Salvage Therapy; Survival Analysis; Topotecan | 2007 |
Pemetrexed in small-cell lung cancer: background and review of the ongoing GALES pivotal trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Etoposide; Glutamates; Guanine; Humans; Lung Neoplasms; Mesothelioma; Pemetrexed; Randomized Controlled Trials as Topic | 2007 |
Safety of irinotecan/cisplatin versus etoposide/cisplatin for patients with extensive-stage small-cell lung cancer: a metaanalysis.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Diarrhea; Etoposide; Female; Hematologic Diseases; Humans; Irinotecan; Lung Neoplasms; Male; Middle Aged; Nausea; Neoplasm Staging; Randomized Controlled Trials as Topic; Vomiting | 2007 |
[Etoposide. A new highly effective cytostatic agent in anaplastic small-cell bronchial carcinoma, other solid tumors and hemoblastoses].
Topics: Bronchial Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Small Cell; Cell Division; Choriocarcinoma; Etoposide; Female; Humans; Leukemia; Liver Neoplasms; Lung Neoplasms; Male; Ovarian Neoplasms; Podophyllotoxin; Pregnancy; Testicular Neoplasms; Uterine Neoplasms | 1981 |
[Short-term induction and cyclic maintenance therapy in inoperable small cell bronchial cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Middle Aged; Prognosis; Vincristine | 1982 |
Chemotherapy of metastatic non-small cell bronchogenic carcinoma.
Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Doxorubicin; Drug Therapy, Combination; Etoposide; Humans; Lung Neoplasms; Prognosis; Vinblastine; Vindesine | 1983 |
Etoposide (VP-16) in the treatment of lung cancer.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Drug Evaluation; Etoposide; Humans; Lung Neoplasms; Podophyllotoxin; Time Factors | 1983 |
Combined platinum etoposide with radiation therapy in limited stage small cell lung cancer: an effective treatment strategy.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Etoposide; Humans; Lung Neoplasms; Neoplasm Staging; Radiotherapy Dosage; Randomized Controlled Trials as Topic; Survival Rate | 1995 |
Oral therapy for small cell lung cancer.
Topics: Administration, Oral; Altretamine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Etoposide; Humans; Ifosfamide; Infusions, Intravenous; Lomustine; Lung Neoplasms; Methotrexate; Procarbazine | 1995 |
Carboplatin/etoposide combination chemotherapy in the treatment of poor prognosis patients with small cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Etoposide; Humans; Lung Neoplasms; Neoplasm Staging; Prognosis; Radiography; Survival Rate | 1995 |
[Mega-dose chemotherapy with peripheral blood stem cell transplantation (PBS-CT) for small cell lung cancer (SCLC)].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Lung Neoplasms; Male; Middle Aged | 1995 |
Chemotherapy with vincristine/ifosfamide/carboplatin/etoposide in small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Clinical Trials as Topic; Etoposide; Humans; Ifosfamide; Lung Neoplasms; Vincristine | 1995 |
Small cell lung cancer. State-of-the-art therapy 1994.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Etoposide; Humans; Lung Neoplasms; Survival Rate | 1995 |
[A case of small cell lung cancer associated with fulminant hepatitis B].
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Hepatitis B; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged | 1994 |
The place of ifosfamide in chemotherapy of small cell lung cancer: the Eastern Cooperative Oncology Group experience and a selected literature update.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Ifosfamide; Lung Neoplasms; Salvage Therapy; Teniposide; Vincristine | 1995 |
Taxol (paclitaxel) in the treatment of lung cancer: the Eastern Cooperative Oncology Group experience.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Clinical Trials, Phase II as Topic; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Randomized Controlled Trials as Topic; Salvage Therapy | 1994 |
[Small cell lung carcinoma: role of thoracic irradiation and its timing in relation to chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Follow-Up Studies; Humans; Lung Neoplasms; Radiotherapy Dosage; Survival Rate; Time Factors; Vincristine | 1994 |
[CAV-PVP chemotherapy and sequential thoracic irradiation (TI) for patients with limited (LD) small cell lung cancer (SCLC)].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Radiotherapy Dosage; Vincristine | 1993 |
Small cell lung cancer and chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Neoplasm Staging; Vincristine | 1994 |
Intensive combined-modality therapy in small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Clinical Trials as Topic; Etoposide; Humans; Ifosfamide; Lung Neoplasms; Vincristine | 1994 |
Prolonged administration of low-daily-dose etoposide: a superior dosing schedule?
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials, Phase II as Topic; Drug Administration Schedule; Etoposide; Humans; Lung Neoplasms; Neoplasms; Pilot Projects; Time Factors | 1994 |
Etoposide: current status and future perspectives in the management of malignant neoplasms.
Topics: Acquired Immunodeficiency Syndrome; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Etoposide; Germinoma; Humans; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma; Neoplasms; Sarcoma, Kaposi; Stomach Neoplasms | 1994 |
Teniposide: overview of its therapeutic potential in adult cancers.
Topics: Acquired Immunodeficiency Syndrome; Adult; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Clinical Trials as Topic; Clinical Trials, Phase I as Topic; Etoposide; Female; Genital Neoplasms, Female; Hodgkin Disease; Humans; Leukemia; Lung Neoplasms; Lymphoma; Lymphoma, Non-Hodgkin; Neoplasms; Sarcoma, Kaposi; Teniposide | 1994 |
Etoposide dosage and pharmacodynamics.
Topics: Carcinoma, Small Cell; Clinical Trials, Phase I as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Humans; Kidney; Kidney Function Tests; Liver; Liver Function Tests; Lung Neoplasms; Lymphoma | 1994 |
Etoposide in the treatment of elderly/poor-prognosis patients with small-cell lung cancer.
Topics: Adult; Aged; Carcinoma, Small Cell; Etoposide; Humans; Incidence; Lung Neoplasms; Prognosis; Survival Rate; United States | 1994 |
Combined modality therapy in small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Contraindications; Cranial Irradiation; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Radiotherapy Dosage; Randomized Controlled Trials as Topic; Treatment Failure | 1994 |
Surgical treatment of stage III lung cancer after chemotherapy and radiotherapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Fluorouracil; Follow-Up Studies; Humans; Iodine Radioisotopes; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Pneumonectomy; Radiotherapy Dosage; Remission Induction | 1994 |
Treatment of the elderly patient with small-cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Etoposide; Female; Humans; Incidence; Lung Neoplasms; Male; United States | 1993 |
Incorporation of radiotherapy fractionation in the combined-modality treatment of limited small-cell lung cancer.
Topics: Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Etoposide; Humans; Lung Neoplasms; Radiation Dosage; Time Factors | 1993 |
Recent developments in chemotherapy treatment of small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Drug Administration Schedule; Drugs, Investigational; Etoposide; Humans; Lung Neoplasms | 1993 |
Roentgenographically occult small-cell lung cancer: case report and review of the literature.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bronchoscopy; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Male; Radiography; Vincristine | 1996 |
Ifosfamide in the treatment of small cell lung cancer.
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Ifosfamide; Lung Neoplasms; Randomized Controlled Trials as Topic; Remission Induction; Survival Rate | 1996 |
[Chemotherapy of small cell lung cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Humans; Lung Neoplasms; Vincristine | 1996 |
[Three cases of secondary acute myeloid leukemia after long-term treatment with oral etoposide].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Phytogenic; Carcinoma, Small Cell; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma, Non-Hodgkin; Male; Neoplasms, Second Primary | 1996 |
[Etoposide in the treatment of small-cell lung cancer].
Topics: Administration, Oral; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials, Phase II as Topic; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Humans; Infusions, Intravenous; Lung Neoplasms | 1996 |
Etoposide phosphate: what, why, where, and how?
Topics: Antineoplastic Agents; Carcinoma, Small Cell; Clinical Trials as Topic; Etoposide; Humans; Lung Neoplasms; Organophosphorus Compounds; Podophyllotoxin | 1996 |
The North American experience with paclitaxel combined with cisplatin or carboplatin in lung cancer.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Lung Neoplasms; Neutropenia; Paclitaxel; Thrombocytopenia; Treatment Outcome | 1996 |
Paraneoplastic subacute cutaneous lupus erythematosus: report of a case associated with cancer of the lung.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Dermatologic Agents; Doxorubicin; Etoposide; Female; Humans; Hydroxychloroquine; Lung Neoplasms; Lupus Erythematosus, Cutaneous; Middle Aged; Paraneoplastic Syndromes | 1997 |
Small cell carcinoma of the esophagus: a case report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Carcinoma, Small Cell; Cisplatin; Disease-Free Survival; Esophageal Neoplasms; Esophagoscopy; Esophagus; Etoposide; Humans; Male; Middle Aged; Tomography, X-Ray Computed | 1997 |
[Concomitant radiochemotherapy for locally advanced bronchial cancers: current results and prospects].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Etoposide; Humans; Lung Neoplasms; Neoplasm Recurrence, Local; Neoplasm Staging; Radiotherapy Dosage; Survival Rate; Treatment Outcome | 1997 |
Small cell lung cancer in the elderly patient.
Topics: Age Factors; Aged; Antineoplastic Agents; Carcinoma, Small Cell; Etoposide; Humans; Lung Neoplasms; Survival Rate | 1997 |
[Adjuvant chemotherapy of lung cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Dactinomycin; Etoposide; Humans; Lung Neoplasms; Mitomycin; Neoplasm Recurrence, Local; Vincristine | 1987 |
[Multimodality therapy for small-cell lung cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Radiotherapy Dosage; Survival Analysis; Vincristine | 1997 |
["State-of-the-art" chemotherapy for small-cell lung cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Deoxycytidine; Docetaxel; Doxorubicin; Drug Administration Schedule; Etoposide; Gemcitabine; Humans; Irinotecan; Lung Neoplasms; Paclitaxel; Taxoids; Topotecan; Vincristine | 1997 |
[International consensus for lung cancer treatment].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Decision Making; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Radiotherapy Dosage; Vincristine | 1997 |
[Small cell carcinoma of the urinary bladder: a case report and review of the Japanese literature].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Etoposide; Humans; Ifosfamide; Male; Middle Aged; Urinary Bladder Neoplasms | 1997 |
[Dose-effect of chemotherapy in bronchial small-cell cancer].
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carcinoma, Small Cell; Carmustine; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Etoposide; Humans; Lung Neoplasms; Randomized Controlled Trials as Topic; Time Factors | 1997 |
The role of carboplatin in the treatment of small-cell lung cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Clinical Trials as Topic; Dose-Response Relationship, Drug; Etoposide; Humans; Lung Neoplasms; Paclitaxel | 1998 |
Etoposide plus ifosfamide plus cisplatin in the treatment of small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Etoposide; Humans; Ifosfamide; Lung Neoplasms | 1998 |
[Small cell lung cancer associated with nephrotic syndrome: remission after chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Glomerulonephritis, IGA; Humans; Lung Neoplasms; Male; Middle Aged; Proteinuria; Remission Induction | 1998 |
[Recent issue in the treatment of small-cell lung cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Drug Administration Schedule; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Lung Neoplasms | 1998 |
[Chemotherapy of small cell bronchogenic carcinoma in a patient on hemodialysis for chronic renal failure. Apropos of a case].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Humans; Kidney Failure, Chronic; Lung Neoplasms; Male; Middle Aged; Renal Dialysis | 1998 |
[Irinotecan-containing combinations in solid tumors, except colonic carcinomas].
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Diarrhea; Docetaxel; Enzyme Inhibitors; Etoposide; Female; Genital Neoplasms, Female; Humans; Irinotecan; Lung Neoplasms; Lymphoma, Non-Hodgkin; Male; Neoplasm Proteins; Neoplasms; Neutropenia; Paclitaxel; Stomach Neoplasms; Taxoids; Topoisomerase I Inhibitors; Treatment Outcome | 1998 |
Concurrent paclitaxel-containing regimens and thoracic radiation therapy for limited-disease small cell lung cancer.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Clinical Trials as Topic; Combined Modality Therapy; Etoposide; Humans; Lung Neoplasms; Paclitaxel | 1999 |
[Small cell neuroendocrine carcinoma of the urinary bladder: a case report].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Neuroendocrine; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cystectomy; Etoposide; Humans; Lymphatic Metastasis; Male; Middle Aged; Urinary Bladder Neoplasms | 1999 |
Combined chemoradiation therapy for limited-stage small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Drug Administration Schedule; Etoposide; Humans; Lung Neoplasms; Radiation-Sensitizing Agents; Radiotherapy Dosage | 1999 |
Management of small cell lung cancer: current state of the art.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cranial Irradiation; Dose Fractionation, Radiation; Etoposide; Humans; Lung Neoplasms; Neoplasm Recurrence, Local; Neoplasm Staging; Radiotherapy Dosage; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Remission Induction; Treatment Outcome | 1999 |
Current role of oral etoposide in the management of small cell lung cancer.
Topics: Administration, Oral; Antineoplastic Agents, Phytogenic; Carcinoma, Small Cell; Etoposide; Humans; Lung Neoplasms | 1999 |
Cyclophosphamide and etoposide for non-small cell and small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Clinical Trials as Topic; Cyclophosphamide; Etoposide; Humans; Lung Neoplasms | 1999 |
Chest radiotherapy in limited-stage small cell lung cancer: facts, questions, prospects.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Etoposide; Humans; Lung Neoplasms; Neoplasm Recurrence, Local; Radiotherapy Dosage; Randomized Controlled Trials as Topic; Retrospective Studies; Survival Rate; Time Factors; Treatment Outcome | 2000 |
Is there a case for cisplatin in the treatment of small-cell lung cancer? A meta-analysis of randomized trials of a cisplatin-containing regimen versus a regimen without this alkylating agent.
Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Etoposide; Female; Humans; Lung Neoplasms; Male; Odds Ratio; Randomized Controlled Trials as Topic; Remission Induction; Risk; Survival Analysis; Treatment Outcome | 2000 |
[Recent topics in chemotherapy for elderly patients with lung cancer].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Lung Neoplasms; Middle Aged | 2000 |
[Treatment of lung cancer--state of the art in 2000].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Survival Analysis; Vincristine | 2000 |
Irinotecan in small-cell lung cancer--Japanese trials.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Etoposide; Humans; Irinotecan; Japan; Lung Neoplasms; Radiation-Sensitizing Agents | 2000 |
A systematic review of the role of etoposide and cisplatin in the chemotherapy of small cell lung cancer with methodology assessment and meta-analysis.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Lung Neoplasms; Prognosis; Randomized Controlled Trials as Topic; Survival Analysis | 2000 |
New state of the art in small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Etoposide; Humans; Irinotecan; Lung Neoplasms; Prognosis; Survival Rate | 2001 |
[Meta-analysis of the value of cisplatin in primary therapy of small-cell bronchial carcinoma].
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Carcinoma, Small Cell; Cisplatin; Data Interpretation, Statistical; Etoposide; Female; Humans; Lung Neoplasms; Male; Quality of Life; Retrospective Studies; Time Factors | 2001 |
Paclitaxel added to the cisplatin/etoposide regimen in extensive-stage small cell lung cancer -- the use of complete response rate as the primary endpoint in phase II trials.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Endpoint Determination; Etoposide; Feasibility Studies; Humans; Lung Neoplasms; Multicenter Studies as Topic; Paclitaxel; Prognosis; Randomized Controlled Trials as Topic; Remission Induction; Survival Rate; Treatment Failure | 2001 |
[A case of small cell carcinoma of the pancreas].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Liver Neoplasms; Middle Aged; Pancreatic Neoplasms; Phosphopyruvate Hydratase | 2001 |
Paclitaxel-based three-drug combinations for the treatment of small cell lung cancer: a review of the Sarah Cannon Cancer Center experience.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Clinical Trials, Phase II as Topic; Etoposide; Humans; Lung Neoplasms; Paclitaxel; Topotecan | 2001 |
Role of topoisomerase I inhibitors in small-cell lung cancer.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Enzyme Inhibitors; Etoposide; Humans; Irinotecan; Lung Neoplasms; Survival Analysis; Topoisomerase I Inhibitors | 2001 |
Current standards of care in small-cell and non-small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Prognosis; Survival Analysis; Treatment Outcome; Vincristine | 2001 |
[Combination chemotherapy with VP-16 in the treatment of lung cancer and malignant lymphoma].
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Clinical Trials, Phase II as Topic; Cytarabine; Etoposide; Humans; Ifosfamide; Lung Neoplasms; Lymphoma; Mesna; Methylprednisolone; Mitoxantrone | 2001 |
Small-cell carcinoma of the esophagus: report of three cases and review of the literature with emphasis on therapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Esophageal Neoplasms; Etoposide; Female; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Radiotherapy, Adjuvant; Retrospective Studies; Treatment Outcome | 2001 |
Carboplatin-etoposide combination in small cell lung cancer patients older than 70 years: a phase II trial.
Topics: Administration, Oral; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Female; Humans; Lung Neoplasms; Male; Neoplasm Staging; Neutropenia; Survival Rate; Treatment Outcome | 2002 |
Irinotecan therapy for small-cell lung cancer.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Enzyme Inhibitors; Etoposide; Humans; Irinotecan; Japan; Lung Neoplasms; Survival Analysis; Topoisomerase I Inhibitors; United States | 2002 |
Limited stage small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cost-Benefit Analysis; Cranial Irradiation; Etoposide; Humans; Lung Neoplasms; Neoplasm Staging | 2001 |
[Irinotecan].
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Etoposide; Humans; Irinotecan; Lung Neoplasms | 2002 |
[Recent progress in the treatment of ED small cell lung cancer].
Topics: Anthracyclines; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Camptothecin; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Imatinib Mesylate; Irinotecan; Lung Neoplasms; Piperazines; Pyrimidines; Vincristine | 2002 |
[Chemotherapy for elderly patients with lung cancer].
Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Deoxycytidine; Docetaxel; Doxorubicin; Etoposide; Gemcitabine; Humans; Lung Neoplasms; Paclitaxel; Taxoids; Vinblastine; Vincristine; Vinorelbine | 2002 |
Small cell carcinoma of prostate: effectiveness of hormonal versus chemotherapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chlorotrianisene; Cyclophosphamide; Diethylstilbestrol; Doxorubicin; Etoposide; Humans; Leuprolide; Male; Middle Aged; Prostatectomy; Prostatic Neoplasms | 1992 |
Carboplatin/etoposide in small cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Hematopoietic Cell Growth Factors; Humans; Lung Neoplasms | 1992 |
The role of chemotherapy in the treatment of lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Combined Modality Therapy; Etoposide; Humans; Lung Neoplasms; Nursing Diagnosis | 1992 |
Lung cancer: a review of current therapeutic modalities.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Neoplasm Staging; Peptichemio; Radiotherapy; Vincristine | 1992 |
Oral etoposide in oncology: an evolving role.
Topics: Administration, Oral; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Humans; Lung Neoplasms | 1992 |
[Small-cell lung cancer: survival analysis over the last 10 years: 1980-1990].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Etoposide; Humans; Lung Neoplasms; Survival Analysis | 1992 |
Chronic oral etoposide in the treatment of lung cancer.
Topics: Administration, Oral; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Clinical Trials as Topic; Drug Administration Schedule; Etoposide; Humans; Lung Neoplasms | 1992 |
Oral etoposide in small cell lung cancer.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Topic; Etoposide; Humans; Lung Neoplasms; Survival Analysis; Treatment Outcome | 1992 |
Chronic oral etoposide: trials at Indiana University and with the Hoosier Oncology Group.
Topics: Administration, Oral; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Clinical Trials as Topic; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Neoplasms; Neoplasms, Germ Cell and Embryonal; Testicular Neoplasms | 1992 |
Developments in therapy for extensive-disease small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Topic; Drug Administration Schedule; Etoposide; Humans; Lung Neoplasms | 1992 |
Adjuvant therapy for neuroendocrine small cell carcinoma of the cervix: review of the literature.
Topics: Adult; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Endocrine Gland Neoplasms; Etoposide; Female; Humans; Middle Aged; Nervous System Neoplasms; Uterine Cervical Neoplasms | 1991 |
[Dose intensity chemotherapy in lung cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Doxorubicin; Drug Administration Schedule; Etoposide; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Mitomycin; Mitomycins; Progesterone; Recombinant Proteins; Remission Induction; Vinblastine; Vincristine | 1990 |
Current status of etoposide in the management of small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Etoposide; Humans; Lung Neoplasms | 1991 |
Dose-intensity meta-analysis of chemotherapy regimens in small-cell carcinoma of the lung.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Evaluation; Etoposide; Humans; Lung Neoplasms; Meta-Analysis as Topic; Podophyllotoxin; Vincristine | 1991 |
[A myelo dysplastic syndrome (refractory anemia with excess of blasts) occurred in a patient with small cell lung cancer during complete response].
Topics: Aged; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Remission Induction; Vincristine | 1990 |
Second-line chemotherapy in small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Resistance; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Remission Induction | 1990 |
Phase II trial of etoposide and cisplatin for refractory small cell lung cancer: a Cancer and Leukemia Group B Study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Multicenter Studies as Topic; Remission Induction; Survival Rate; Time Factors | 1990 |
Carboplatin in small cell lung cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Humans; Lung Neoplasms; Organoplatinum Compounds | 1990 |
[Small cell lung carcinoma. Value of the evaluation of extension for the therapeutic strategy].
Topics: Adrenal Gland Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Topic; Combined Modality Therapy; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Multicenter Studies as Topic; Neoplasm Staging; Prognosis; Prospective Studies; Spinal Cord Neoplasms | 1990 |
Combination chemotherapy and radiotherapy for small-cell carcinoma of the esophagus. A case report of long-term survival and review of the literature.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Esophageal Neoplasms; Etoposide; Female; Humans; Prognosis; Remission Induction; Vincristine | 1990 |
Ifosfamide in small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Ifosfamide; Lung Neoplasms | 1989 |
Cisplatin for small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Lung Neoplasms; Remission Induction | 1989 |
[Recent trends of chemotherapy in small cell lung cancer: a slow but steady progress].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Vincristine | 1989 |
[Chemotherapy of small cell lung cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Organoplatinum Compounds; Vincristine | 1988 |
Cisplatin plus etoposide in small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Lung Neoplasms | 1988 |
Small cell carcinoma of the urinary bladder: a case of remarkable remission with combined chemotherapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Lymphatic Metastasis; Male; Remission Induction; Tomography, X-Ray Computed; Urinary Bladder Neoplasms | 1988 |
Etoposide (VP-16-213). Current status of an active anticancer drug.
Topics: Animals; Carcinoma, Small Cell; Clinical Trials as Topic; DNA; Drug Administration Schedule; Drug Evaluation; Drug Evaluation, Preclinical; Drug Resistance; Etoposide; Female; Hodgkin Disease; Humans; Leukemia; Lung Neoplasms; Lymphoma; Male; Mice; Podophyllotoxin; Testicular Neoplasms; Tissue Distribution | 1985 |
Current chemotherapy of small cell lung cancer.
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Complement Membrane Attack Complex; Complement System Proteins; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Humans; Lomustine; Lung Neoplasms; Methotrexate; Mitomycin; Mitomycins; Podophyllotoxin; Procarbazine; Prognosis; Time Factors; Vincristine | 1986 |
High dose chemotherapy in solid tumours in adults.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Breast Neoplasms; Carcinoma, Small Cell; Carmustine; Cell Separation; Cisplatin; Colonic Neoplasms; Cyclophosphamide; Etoposide; Glioma; Humans; Lung Neoplasms; Male; Melanoma; Melphalan; Neoplasms; Testicular Neoplasms; Whole-Body Irradiation | 1986 |
The use of VP-16 plus cisplatin during induction chemotherapy for small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Prospective Studies; Random Allocation; Remission Induction; Vincristine | 1986 |
Cisplatin plus VP-16 in small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Lung Neoplasms | 1986 |
Clinical trials of cyclophosphamide, etoposide, and vincristine in the treatment of small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Random Allocation; Vincristine | 1986 |
Initial therapy with cisplatin plus VP-16 in small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Prospective Studies; Random Allocation; Remission Induction; Vincristine | 1986 |
Doxorubicin, cyclophosphamide, etoposide and platinum, doxorubicin, cyclophosphamide and etoposide for small-cell carcinoma of the lung.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Prognosis; Remission Induction | 1986 |
Oral etoposide in small-cell lung cancer.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Topic; Etoposide; Humans; Lung Neoplasms | 1986 |
Outpatient administration of VP-16 and cisplatin.
Topics: Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Lung Neoplasms | 1986 |
529 trial(s) available for etoposide and Carcinoma, Oat Cell
Article | Year |
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Etoposide and cisplatin versus irinotecan and cisplatin in patients with limited-stage small-cell lung cancer treated with etoposide and cisplatin plus concurrent accelerated hyperfractionated thoracic radiotherapy (JCOG0202): a randomised phase 3 study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Chemoradiotherapy; Cisplatin; Dose Fractionation, Radiation; Etoposide; Female; Humans; Irinotecan; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging | 2014 |
Italian multicenter phase III randomized study of cisplatin-etoposide with or without bevacizumab as first-line treatment in extensive stage small cell lung cancer: treatment rationale and protocol design of the GOIRC-AIFA FARM6PMFJM trial.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carcinoma, Small Cell; Cisplatin; Clinical Protocols; Etoposide; Female; Humans; Italy; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Research Design; Survival Analysis; Treatment Outcome; Young Adult | 2015 |
Phase I/IIa study of sequential chemotherapy regimen of bendamustine/irinotecan followed by etoposide/carboplatin in untreated patients with extensive disease small cell lung cancer (EDSCLC).
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Biomarkers, Tumor; Brain Diseases, Metabolic; Camptothecin; Carboplatin; Carcinoma, Small Cell; Disease-Free Survival; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Administration Schedule; Endonucleases; Etoposide; Fatigue; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Irinotecan; Kaplan-Meier Estimate; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Mitosis; Multiple Organ Failure; Pneumonia; Treatment Outcome; Weight Loss | 2015 |
Urinary kidney injury molecule-1 and monocyte chemotactic protein-1 are noninvasive biomarkers of cisplatin-induced nephrotoxicity in lung cancer patients.
Topics: Acute Kidney Injury; Acute-Phase Proteins; Adenocarcinoma; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; beta 2-Microglobulin; Biomarkers; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Chemokine CCL2; Cisplatin; Creatinine; Etoposide; Female; Hepatitis A Virus Cellular Receptor 1; Humans; Lipocalin-2; Lipocalins; Lung Neoplasms; Male; Membrane Glycoproteins; Middle Aged; Neoplasm Proteins; Proto-Oncogene Proteins; Receptors, Virus; ROC Curve; Vinblastine; Vinorelbine | 2015 |
Belotecan/cisplatin versus etoposide/cisplatin in previously untreated patients with extensive-stage small cell lung carcinoma: a multi-center randomized phase III trial.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Disease-Free Survival; Etoposide; Female; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged | 2016 |
Phase III randomised trial of doxorubicin-based chemotherapy compared with platinum-based chemotherapy in small-cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Monitoring, Physiologic; Survival Analysis | 2008 |
Irinotecan plus carboplatin versus oral etoposide plus carboplatin in extensive small-cell lung cancer: a randomized phase III trial.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carboplatin; Carcinoma, Small Cell; Etoposide; Female; Humans; Irinotecan; Lung Neoplasms; Male; Middle Aged; Prognosis; Survival Analysis | 2008 |
Comparison of cisplatin-paclitaxel combination versus cisplatin-etoposide in patients with small-cell lung cancer: a Phase III study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Patient Compliance | 2008 |
A phase II study of paclitaxel + etoposide + cisplatin + concurrent radiation therapy for previously untreated limited stage small cell lung cancer (E2596): a trial of the Eastern Cooperative Oncology Group.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Etoposide; Humans; Lung Neoplasms; Middle Aged; Neoplasm Staging; Paclitaxel | 2009 |
Phase II clinical trial of neoadjuvant alternating doublet chemotherapy with ifosfamide/doxorubicin and etoposide/cisplatin in small-cell urothelial cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Cystectomy; Disease-Free Survival; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Kaplan-Meier Estimate; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Prospective Studies; Time Factors; Treatment Outcome; Urinary Bladder Neoplasms; Urothelium | 2009 |
[Pre-treatment and treatment-induced neuron-specific enolase in patients with small-cell lung cancer: an open prospective study].
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carboplatin; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Disease-Free Survival; Etoposide; Humans; Lung Neoplasms; Neoplasm Proteins; Phosphopyruvate Hydratase; Prospective Studies; Remission Induction; Survival Analysis; Tomography, X-Ray Computed; Treatment Outcome; Tumor Burden | 2010 |
A phase I trial of sorafenib combined with cisplatin/etoposide or carboplatin/pemetrexed in refractory solid tumor patients.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Glutamates; Guanine; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Niacinamide; Pemetrexed; Phenylurea Compounds; Pyridines; Sorafenib; Treatment Outcome | 2011 |
Phase II study of cisplatin/etoposide and endostar for extensive-stage small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Disease-Free Survival; Endostatins; Etoposide; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Recombinant Proteins; Survival Rate; Treatment Outcome | 2011 |
Phase I-II trial of gemcitabine-based first-line chemotherapies for small cell lung cancer in elderly patients with performance status 0-2: the G-STEP trial.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Deoxycytidine; Disease-Free Survival; Etoposide; Female; Gemcitabine; Humans; Lung Neoplasms; Male; Multivariate Analysis; Prognosis; Proportional Hazards Models; Quality of Life; Treatment Outcome; Vinblastine; Vinorelbine | 2012 |
Small cell carcinoma of the uterine cervix: clinical outcome of concurrent chemoradiotherapy with a multidrug regimen.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chemoradiotherapy; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Endpoint Determination; Etoposide; Female; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Middle Aged; Neutropenia; Prednisone; Treatment Outcome; Uterine Cervical Neoplasms; Vincristine | 2013 |
Results of a phase II study with doxorubicin, etoposide, and cisplatin in patients with fully characterized small-cell carcinoma of the prostate.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Small Cell; Cisplatin; Disease Progression; Doxorubicin; Drug Administration Schedule; Etoposide; Humans; Infusions, Intravenous; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Multivariate Analysis; Proportional Hazards Models; Prostatic Neoplasms; Survival Analysis; Treatment Outcome | 2002 |
A Phase I-II study of sequential administration of topotecan and oral etoposide (toposiomerase I and II inhibitors) in the treatment of patients with small cell lung carcinoma.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Neutropenia; Topotecan | 2002 |
Standard versus intensified chemotherapy with granulocyte colony-stimulating factor support in small-cell lung cancer: a prospective European Organization for Research and Treatment of Cancer-Lung Cancer Group Phase III Trial-08923.
Topics: Adult; Aged; Antibiotic Prophylaxis; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Europe; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Statistics, Nonparametric; Survival Rate; Treatment Outcome | 2002 |
Cisplatin-etoposide alternating with topotecan in patients with extensive stage small cell lung cancer (SCLC). A multicenter phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Disease Progression; Drug Administration Schedule; Etoposide; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Neutropenia; Survival; Thrombocytopenia; Topotecan; Treatment Outcome | 2002 |
Early tandem high-dose ifosfamide, carboplatin, etoposide therapy with stem cell rescue for small-cell lung cancer: brief report on the results of a phase-I/II trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Dose-Response Relationship, Drug; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Hematologic Diseases; Hematopoietic Stem Cells; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Survival Rate | 2002 |
Effect of grapefruit juice intake on etoposide bioavailability.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Phytogenic; Area Under Curve; Beverages; Biological Availability; Carcinoma, Small Cell; Chromatography, High Pressure Liquid; Citrus paradisi; Cross-Over Studies; Etoposide; Female; Food-Drug Interactions; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Pilot Projects | 2002 |
Cisplatin and etoposide regimen is superior to cyclophosphamide, epirubicin, and vincristine regimen in small-cell lung cancer: results from a randomized phase III trial with 5 years' follow-up.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Epirubicin; Etoposide; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Quality of Life; Remission Induction; Survival Rate; Vincristine | 2002 |
Long-term survival in SCLC after treatment with paclitaxel, carboplatin and etoposide--a phase II study.
Topics: Adult; Aged; Carboplatin; Carcinoma, Small Cell; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Survival Analysis; Time Factors; Treatment Outcome | 2003 |
Sequential administration of cisplatin-etoposide followed by topotecan in patients with extensive stage small cell lung cancer. A multicenter phase II study.
Topics: Adult; Aged; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Time Factors; Topotecan; Treatment Outcome | 2003 |
Phase II study of carboplatin and 1-h intravenous etoposide and paclitaxel in a novel sequence as first-line treatment of patients with small-cell lung cancer.
Topics: Adult; Aged; Carboplatin; Carcinoma, Small Cell; Etoposide; Female; Humans; Injections, Intravenous; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Survival Rate; Time Factors; Treatment Outcome | 2003 |
[Teniposide and cisplatin compared with etoposide and cisplatin for treatment of small cell lung cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Teniposide; Treatment Outcome | 2002 |
Outpatient intensive chemotherapy for small cell lung cancer: five years experience of modified 'ICE' ifosfamide carboplatin and etoposide.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Mesna; Middle Aged; Outpatients; Prognosis; Survival | 2002 |
Economic evaluation of antibiotic prophylaxis in small-cell lung cancer patients receiving chemotherapy: an EORTC double-blind placebo-controlled phase III study (08923).
Topics: Administration, Oral; Adult; Aged; Antibiotic Prophylaxis; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cost Savings; Cost-Benefit Analysis; Cyclophosphamide; Double-Blind Method; Doxorubicin; Etoposide; Female; Fever; Granulocyte Colony-Stimulating Factor; Health Care Costs; Hospitalization; Humans; Incidence; Leukopenia; Lung Neoplasms; Male; Middle Aged; Placebos; Risk Factors; Survival | 2003 |
Phase I/II trial of gemcitabine plus cisplatin and etoposide in patients with small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Deoxycytidine; Etoposide; Female; Gemcitabine; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Survival; Treatment Outcome | 2003 |
Phase I/II trial of weekly cisplatin, etoposide, and irinotecan chemotherapy for metastatic lung cancer: JCOG 9507.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Diarrhea; Dose-Response Relationship, Drug; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Infusions, Intravenous; Irinotecan; Leukopenia; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neutropenia; Survival; Thrombocytopenia | 2003 |
Randomized phase II study of cisplatin, irinotecan and etoposide combinations administered weekly or every 4 weeks for extensive small-cell lung cancer (JCOG9902-DI).
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Etoposide; Female; Humans; Irinotecan; Male; Middle Aged; Prospective Studies; Survival Rate | 2003 |
Alternating chemotherapy with etoposide plus cisplatin and topotecan plus paclitaxel in patients with untreated, extensive-stage small cell lung carcinoma: a phase II trial of the North Central Cancer Treatment Group.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Etoposide; Female; Humans; Illinois; Indiana; Iowa; Lung Neoplasms; Male; Middle Aged; Minnesota; Nebraska; Neoplasm Staging; North Dakota; Paclitaxel; South Dakota; Survival Analysis; Topotecan; Treatment Outcome | 2003 |
A phase I study of topotecan/paclitaxel alternating with etoposide/cisplatin and thoracic irradiation in patients with limited small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Recurrence, Local; Paclitaxel; Topotecan | 2003 |
Randomized phase II study of daily versus continuous-infusion schedules of topotecan in the treatment of extensive-stage small cell lung cancers.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Etoposide; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Survival Analysis; Topotecan; Treatment Outcome | 2003 |
Phase I/II study of altered schedule of cisplatin and etoposide administration and concurrent accelerated hyperfractionated thoracic radiotherapy for limited-stage small-cell lung cancer.
Topics: Aged; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Carcinoma, Small Cell; Cisplatin; Cohort Studies; Combined Modality Therapy; Drug Administration Schedule; Etoposide; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Treatment Outcome | 2003 |
Cisplatin and etoposide alternating ifosfamide, vincristine, epirubicin in small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Epirubicin; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Saudi Arabia; Survival Rate; Vincristine | 2003 |
Dose-dense therapy with a novel irinotecan regimen for small-cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Female; Humans; Irinotecan; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Treatment Outcome | 2003 |
To predict response chemotherapy using technetium-99m tetrofosmin chest images in patients with untreated small cell lung cancer and compare with p-glycoprotein, multidrug resistance related protein-1, and lung resistance-related protein expression.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biomarkers, Tumor; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Injections, Intravenous; Lung Neoplasms; Male; Middle Aged; Neoplasm Proteins; Organophosphorus Compounds; Organotechnetium Compounds; Prognosis; Radionuclide Imaging; Radiopharmaceuticals; Thorax; Treatment Outcome; Vault Ribonucleoprotein Particles | 2003 |
Randomized phase III trial of paclitaxel, etoposide, and carboplatin versus carboplatin, etoposide, and vincristine in patients with small-cell lung cancer.
Topics: Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Disease Progression; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Hematologic Diseases; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Paclitaxel; Patient Selection; Prognosis; Proportional Hazards Models; Risk Factors; Survival Analysis; Treatment Outcome; Vincristine | 2003 |
Pharmacokinetics of etoposide in cancer patients treated with high-dose etoposide and with dexrazoxane (ICRF-187) as a rescue agent.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Brain Neoplasms; Carcinoma, Small Cell; Catheters, Indwelling; Chromatography, High Pressure Liquid; Etoposide; Humans; Infusions, Intravenous; Lung Neoplasms; Razoxane | 2004 |
Phase I study of weekly alternating therapy with irinotecan/cisplatin and etoposide/cisplatin for patients with small-cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Infusions, Intravenous; Injections, Subcutaneous; Irinotecan; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Prognosis; Survival Analysis; Treatment Outcome | 2003 |
Phase II trial of cisplatin/etoposide and concurrent radiotherapy followed by paclitaxel/carboplatin consolidation for limited small-cell lung cancer: Southwest Oncology Group 9713.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Etoposide; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Treatment Outcome | 2004 |
Early concurrent chemoradiotherapy with prolonged oral etoposide and cisplatin for limited-stage small-cell lung cancer.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged | 2003 |
Phase I study of G3139, a bcl-2 antisense oligonucleotide, combined with carboplatin and etoposide in patients with small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Disease-Free Survival; Dose-Response Relationship, Drug; Etoposide; Female; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Oligonucleotides, Antisense; Proto-Oncogene Proteins c-bcl-2; Survival Rate; Thionucleotides; United States | 2004 |
Phase II study of oral etoposide and intravenous paclitaxel in extensive-stage small cell lung cancer.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Drug Synergism; Etoposide; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Paclitaxel; Survival Analysis; Treatment Outcome | 2004 |
[Concurrent radiotherapy combined with carboplatin and etoposide in limited stage small cell lung cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Etoposide; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Radiotherapy, High-Energy; Survival Rate | 2004 |
Long-term results of a phase III trial comparing once-daily radiotherapy with twice-daily radiotherapy in limited-stage small-cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Dose Fractionation, Radiation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Radiotherapy; Survival Analysis | 2004 |
Topoisomerase I inhibitors in small-cell lung cancer. The Japanese experience.
Topics: Aged; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Enzyme Inhibitors; Etoposide; Female; Humans; Irinotecan; Japan; Lung Neoplasms; Male; Middle Aged; Remission Induction; Survival Rate; Topoisomerase I Inhibitors | 2004 |
Irinotecan in advanced lung cancer: focus on North American trials.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Deoxycytidine; Enzyme Inhibitors; Etoposide; Gemcitabine; Humans; Irinotecan; Lung Neoplasms; North America; Radiotherapy, Adjuvant; Ribonucleotide Reductases; Survival Rate; Taxoids; Topoisomerase I Inhibitors; Vindesine | 2004 |
Multi-institutional phase II trial of irinotecan, cisplatin, and etoposide for sensitive relapsed small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Irinotecan; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Neutropenia; Salvage Therapy; Survival Analysis; Thrombocytopenia; Treatment Outcome | 2004 |
Phase I study of tirapazamine plus cisplatin/etoposide and concurrent thoracic radiotherapy in limited-stage small cell lung cancer (S0004): a Southwest Oncology Group study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Esophagitis; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neutropenia; Radiation-Sensitizing Agents; Radiotherapy Dosage; Tirapazamine; Triazines; Vomiting | 2004 |
Prospective randomized phase III trial of etoposide/cisplatin versus high-dose epirubicin/cisplatin in small-cell lung cancer.
Topics: Adult; Aged; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cranial Irradiation; Dose-Response Relationship, Drug; Drug Administration Schedule; Epirubicin; Erythrocyte Transfusion; Etoposide; Female; Hospitalization; Humans; Lung Neoplasms; Male; Middle Aged; Platelet Transfusion; Prospective Studies; Radiotherapy, Adjuvant | 2004 |
Cisplatin/etoposide chemotherapy combined with twice daily thoracic radiotherapy for limited small-cell lung cancer: a clinical phase II trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Etoposide; Feasibility Studies; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Radiotherapy; Radiotherapy Dosage | 2005 |
A multicenter, randomized, Phase II study of cisplatin, etoposide, and gemcitabine or cisplatin plus gemcitabine as first-line treatment in patients with poor-prognosis small cell lung carcinoma.
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Deoxycytidine; Etoposide; Female; Gemcitabine; Humans; Lung Neoplasms; Male; Middle Aged; Survival Analysis; Treatment Outcome | 2005 |
Platinum-etoposide chemotherapy in elderly patients with small-cell lung cancer: results of a randomized multicenter phase II study assessing attenuated-dose or full-dose with lenograstim prophylaxis--a Forza Operativa Nazionale Italiana Carcinoma Polmona
Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Dose-Response Relationship, Drug; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Infusions, Intravenous; Lenograstim; Lung Neoplasms; Male; Recombinant Proteins; Treatment Outcome | 2005 |
Vindesine and etoposide: A practical and well-tolerated therapy for elderly patients or patients in reduced clinical condition with extensive-stage small-cell lung cancer (SCLC).
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Small Cell; Drug Therapy, Combination; Etoposide; Female; Humans; Male; Middle Aged; Neoplasm Staging; Survival Rate; Vindesine | 2005 |
A phase III trial evaluating the combination of cisplatin, etoposide, and radiation therapy with or without tamoxifen in patients with limited-stage small cell lung cancer: Cancer and Leukemia Group B Study (9235).
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Cranial Irradiation; Dose Fractionation, Radiation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Survival Analysis; Tamoxifen | 2005 |
Second-line chemotherapy in recurrent small cell lung cancer. Results from a crossover schedule after primary treatment with cisplatin and etoposide (EP-regimen) or cyclophosphamide, epirubicin, and vincristin (CEV-regimen).
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cross-Over Studies; Cyclophosphamide; Drug Resistance, Neoplasm; Epirubicin; Etoposide; Female; Health Status; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Multivariate Analysis; Neoplasm Recurrence, Local; Palliative Care; Prognosis; Treatment Outcome; Vincristine | 2005 |
Split-course versus continuous thoracic radiation therapy for limited-stage small-cell lung cancer: final report of a randomized phase III trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dose Fractionation, Radiation; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Survival Analysis; Vincristine | 2005 |
Results of combined-modality therapy for limited-stage small cell lung carcinoma in the elderly.
Topics: Adult; Age Distribution; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Radiotherapy Dosage; Survival Rate; Treatment Outcome | 2005 |
Phase II trial of postoperative adjuvant cisplatin and etoposide in patients with completely resected stage I-IIIa small cell lung cancer: the Japan Clinical Oncology Lung Cancer Study Group Trial (JCOG9101).
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Etoposide; Female; Follow-Up Studies; Humans; Japan; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Pneumonectomy; Postoperative Care; Proportional Hazards Models; Survival Analysis; Treatment Outcome | 2005 |
Randomized phase III trial of dose-dense chemotherapy supported by whole-blood hematopoietic progenitors in better-prognosis small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Ifosfamide; Incidence; Lung Neoplasms; Male; Middle Aged; Neutropenia; Prognosis; Recombinant Proteins; Severity of Illness Index; Survival Analysis; Transplantation, Autologous; Treatment Outcome | 2005 |
Phase I study of thoracic radiation dose escalation with concurrent chemotherapy for patients with limited small-cell lung cancer: Report of Radiation Therapy Oncology Group (RTOG) protocol 97-12.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Endpoint Determination; Esophagitis; Etoposide; Female; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Nausea; Radiotherapy Dosage; Survival Rate; Vomiting | 2005 |
Topotecan and etoposide as first-line therapy for extensive disease small cell lung cancer: a phase II trial of a platinum-free regimen.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Etoposide; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Neutropenia; Survival Analysis; Thrombocytopenia; Topotecan; Treatment Outcome | 2005 |
Phase II study of irinotecan plus cisplatin induction followed by concurrent twice-daily thoracic irradiation with etoposide plus cisplatin chemotherapy for limited-disease small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Dose-Response Relationship, Radiation; Etoposide; Female; Follow-Up Studies; Humans; Irinotecan; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Radiotherapy Dosage; Radiotherapy, Adjuvant; Remission Induction; Risk Assessment; Survival Analysis; Treatment Outcome | 2005 |
Randomized phase III intergroup trial of etoposide and cisplatin with or without paclitaxel and granulocyte colony-stimulating factor in patients with extensive-stage small-cell lung cancer: Cancer and Leukemia Group B Trial 9732.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Disease Progression; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Paclitaxel; Prospective Studies; Recombinant Proteins; Survival Rate; Time Factors | 2005 |
Study of paclitaxel, etoposide, and cisplatin chemotherapy combined with twice-daily thoracic radiotherapy for patients with limited-stage small-cell lung cancer: a Radiation Therapy Oncology Group 9609 phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Disease Progression; Etoposide; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Survival Analysis | 2005 |
Phase I study of etoposide, cisplatin and irinotecan triplet in patients with advanced-stage small-cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brain Neoplasms; Camptothecin; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Survival Analysis | 2005 |
A randomised phase II study of the efficacy and safety of intravenous topotecan in combination with either cisplatin or etoposide in patients with untreated extensive disease small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Survival Rate; Topotecan; Treatment Outcome | 2005 |
Irinotecan and etoposide for previously untreated extensive-disease small cell lung cancer: a phase II trial of West Japan Thoracic Oncology Group.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Etoposide; Female; Humans; Infusions, Intravenous; Irinotecan; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Survival Rate; Treatment Outcome | 2005 |
Pilot study of concurrent etoposide and cisplatin plus accelerated hyperfractionated thoracic radiotherapy followed by irinotecan and cisplatin for limited-stage small cell lung cancer: Japan Clinical Oncology Group 9903.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Dose Fractionation, Radiation; Etoposide; Female; Humans; Irinotecan; Lung Neoplasms; Male; Middle Aged; Pilot Projects; Time Factors; Treatment Outcome | 2005 |
[The effect of chemo-radiotherapy on the remission and survival in patients with limited stage small cell lung cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Esophagitis; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Pneumonia; Radiotherapy, Adjuvant; Remission Induction; Survival Analysis; Treatment Outcome | 2005 |
A phase I/II study of docetaxel, etoposide, and carboplatin before concurrent chemoradiotherapy with cisplatin and etoposide in limited-stage small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Docetaxel; Etoposide; Female; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Neutropenia; Taxoids; Treatment Outcome | 2006 |
A phase I trial defining the maximum tolerated systemic exposure of topotecan in combination with Carboplatin and Etoposide in extensive stage small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carboplatin; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Survival; Topotecan; Treatment Outcome | 2005 |
Double-cycle, high-dose ifosfamide, carboplatin, and etoposide followed by peripheral blood stem-cell transplantation for small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Diarrhea; Etoposide; Female; Humans; Ifosfamide; Kidney; Leukocyte Count; Lung Neoplasms; Male; Radiotherapy Dosage; Stem Cell Transplantation; Survival Analysis; Treatment Outcome | 2005 |
Paclitaxel/carboplatin/etoposide versus paclitaxel/topotecan for extensive-stage small cell lung cancer: a Minnie Pearl Cancer Research Network randomized, prospective phase II trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Organophosphorus Compounds; Paclitaxel; Topotecan | 2005 |
Prevention of chemotherapy-induced febrile neutropenia by prophylactic antibiotics plus or minus granulocyte colony-stimulating factor in small-cell lung cancer: a Dutch Randomized Phase III Study.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antibiotic Prophylaxis; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Ciprofloxacin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Fever; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Middle Aged; Neutropenia; Risk Factors; Roxithromycin; Treatment Outcome | 2005 |
Ifosfamide, carboplatin, and etoposide with midcycle vincristine versus standard chemotherapy in patients with small-cell lung cancer and good performance status: clinical and quality-of-life results of the British Medical Research Council multicenter ran
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Prospective Studies; Quality of Life; Statistics, Nonparametric; Survival Analysis; United Kingdom; Vincristine | 2005 |
Second-line chemotherapy with weekly paclitaxel and gemcitabine in patients with small-cell lung cancer pretreated with platinum and etoposide: a single institution phase II trial.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Deoxycytidine; Etoposide; Female; Gemcitabine; Humans; Lung Neoplasms; Male; Middle Aged; Paclitaxel | 2006 |
Sequential versus alternating administration of cisplatin/etoposide and topotecan as first-line treatment in extensive-stage small-cell lung cancer: preliminary results of a Phase III Trial of the Hellenic Oncology Research Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Etoposide; Female; Humans; Injections, Intravenous; Lung Neoplasms; Male; Middle Aged; Survival Analysis; Topotecan | 2005 |
A randomized phase II trial of irinotecan plus carboplatin versus etoposide plus carboplatin treatment in patients with extended disease small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carboplatin; Carcinoma, Small Cell; Etoposide; Female; Humans; Irinotecan; Lung Neoplasms; Male; Middle Aged | 2006 |
A phase I trial of carboplatin and etoposide for elderly (>or=75 year-old) patients with small-cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carboplatin; Carcinoma, Small Cell; Creatinine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Eruptions; Etoposide; Female; Gastrointestinal Tract; Humans; Injections, Intravenous; Liver Function Tests; Lung Neoplasms; Male; Nausea; Neutropenia; Survival Analysis; Thrombocytopenia; Treatment Outcome; Vomiting | 2006 |
Concurrent chemotherapy (carboplatin, paclitaxel, etoposide) and involved-field radiotherapy in limited stage small cell lung cancer: a Dutch multicenter phase II study.
Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Etoposide; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Prognosis; Radiation Injuries; Survival Analysis; Treatment Outcome | 2006 |
Phase I study of hypofractionated dose-escalated thoracic radiotherapy for limited-stage small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Dose Fractionation, Radiation; Etoposide; Female; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Radiotherapy, Conformal; Treatment Outcome | 2006 |
Epirubicin/paclitaxel/etoposide in extensive-stage small-cell lung cancer: a phase I-II study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Epirubicin; Etoposide; Female; Humans; Infusions, Intravenous; Injections, Intravenous; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Paclitaxel; Treatment Outcome | 2006 |
Randomized phase III trial of cisplatin/irinotecan versus cisplatin/etoposide in patients with extensive-stage small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Irinotecan; Lung Neoplasms; Survival Rate | 2006 |
Randomized phase III trial comparing irinotecan/cisplatin with etoposide/cisplatin in patients with previously untreated extensive-stage disease small-cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Irinotecan; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging | 2006 |
Open-label, multicenter, randomized, phase III study comparing oral topotecan/cisplatin versus etoposide/cisplatin as treatment for chemotherapy-naive patients with extensive-disease small-cell lung cancer.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Quality of Life; Topotecan | 2006 |
Efficient palliation in patients with small-cell lung cancer by a combination of paclitaxel, etoposide and carboplatin: quality of life and 6-years'-follow-up results from a randomised phase III trial.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Prognosis; Prospective Studies; Quality of Life; Survival Rate; Vincristine | 2006 |
A novel metronomic chemotherapy regimen of weekly platinum and daily oral etoposide in high-risk non-small cell lung cancer patients.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged | 2006 |
Evaluation of curative and palliative radiotherapy efficacy in extensive stage small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Dose Fractionation, Radiation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Palliative Care; Survival Analysis; Turkey | 2006 |
Tc-99m MIBI SPECT in prediction of prognosis in patients with small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Outcome Assessment, Health Care; Prognosis; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Survival Analysis; Survival Rate; Technetium Tc 99m Sestamibi; Tomography, Emission-Computed, Single-Photon; Treatment Outcome; Turkey | 2006 |
Early compared with late radiotherapy in combined modality treatment for limited disease small-cell lung cancer: a London Lung Cancer Group multicenter randomized clinical trial and meta-analysis.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Cranial Irradiation; Cyclophosphamide; Dose Fractionation, Radiation; Doxorubicin; Etoposide; Female; Humans; London; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Radiotherapy, Adjuvant; Survival Analysis; Time Factors; Treatment Outcome; Vincristine | 2006 |
Phase II study of amrubicin in previously untreated patients with extensive-disease small cell lung cancer: West Japan Thoracic Oncology Group (WJTOG) study.
Topics: Adult; Aged; Anthracyclines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Etoposide; Female; Humans; Infusions, Intravenous; Japan; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Salvage Therapy; Time Factors; Treatment Outcome | 2007 |
Phase I and pharmacologic study of sequential topotecan-carboplatin-etoposide in patients with extensive stage small cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Enzyme Inhibitors; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Topotecan; Treatment Outcome | 2006 |
Phase II study of etoposide and cisplatin with concurrent twice-daily thoracic radiotherapy followed by irinotecan and cisplatin in patients with limited-disease small-cell lung cancer: West Japan Thoracic Oncology Group 9902.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Diarrhea; Disease-Free Survival; Etoposide; Female; Fever; Humans; Infections; Irinotecan; Japan; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Neutropenia; Radiotherapy Dosage; Radiotherapy, Adjuvant; Severity of Illness Index; Survival Analysis; Treatment Outcome | 2006 |
A phase I study of dose-dense topotecan given upfront to standard therapy in patients with small cell lung cancer.
Topics: Anorexia; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Hematologic Diseases; Humans; Karnofsky Performance Status; Lung Neoplasms; Male; Middle Aged; Nausea; Neoplasm Staging; Radiotherapy, Adjuvant; Remission Induction; Survival Rate; Topotecan; Treatment Outcome | 2006 |
Phase I North Central Cancer Treatment Group Trial-N9923 of escalating doses of twice-daily thoracic radiation therapy with amifostine and with alternating chemotherapy in limited stage small-cell lung cancer.
Topics: Adult; Aged; Amifostine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Quality Control; Quality of Life; Radiation-Sensitizing Agents; Radiotherapy Dosage; Topotecan | 2007 |
A phase II trial of cisplatin and irinotecan alternating with doxorubicin, cyclophosphamide and etoposide in previously untreated patients with extensive-disease small-cell lung cancer.
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Diarrhea; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Injections, Intravenous; Irinotecan; Lung Neoplasms; Male; Middle Aged; Neutropenia; Prospective Studies; Survival Analysis; Thrombocytopenia; Treatment Outcome | 2007 |
Standard versus dose-intensified chemotherapy with sequential reinfusion of hematopoietic progenitor cells in small cell lung cancer patients with favorable prognosis.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Disease Progression; Erythrocyte Transfusion; Etoposide; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Platelet Transfusion; Prognosis; Recombinant Proteins; Survival Rate | 2007 |
[Randomised phase II study evaluating oral combination chemotherapy (CCNU, cyclophosphamide, etoposide) and intravenous chemotherapy as second-line treatment for relapsed small cell bronchial carcinoma (Trial GFPC0501)].
Topics: Administration, Oral; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bronchial Neoplasms; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Health Resources; Humans; Injections, Intravenous; Lomustine; Neoplasm Recurrence, Local; Quality of Life; Remission Induction; Survival Rate; Treatment Outcome; Vincristine | 2007 |
Randomised phase III trial of carboplatin plus etoposide vs split doses of cisplatin plus etoposide in elderly or poor-risk patients with extensive disease small-cell lung cancer: JCOG 9702.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Treatment Outcome | 2007 |
Phase II trial of paclitaxel-topotecan-etoposide followed by consolidation chemoradiotherapy for limited-stage small cell lung cancer: CALGB 30002.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Dose-Response Relationship, Drug; Etoposide; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Retrospective Studies; Severity of Illness Index; Survival Rate; Topotecan; Treatment Outcome | 2007 |
Results of a phase II study of high-dose thoracic radiation therapy with concurrent cisplatin and etoposide in limited-stage small-cell lung cancer (NCCTG 95-20-53).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Etoposide; Female; Humans; Immunohistochemistry; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Prognosis; Radiotherapy, High-Energy; Risk Assessment; Survival Analysis; Treatment Outcome | 2007 |
Combination chemotherapy with cisplatin, etoposide and irinotecan in patients with extensive small-cell lung cancer: A phase II study of the Hellenic Co-operative Oncology Group.
Topics: Adult; Aged; Camptothecin; Carcinoma, Small Cell; Cisplatin; Disease Progression; Dose-Response Relationship, Drug; Drug Therapy, Combination; Etoposide; Female; Humans; Irinotecan; Lung Neoplasms; Male; Middle Aged; Survival Rate | 2007 |
Phase III study of cyclophosphamide, doxorubicin, and etoposide compared with carboplatin and paclitaxel in patients with extensive disease small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cause of Death; Cyclophosphamide; Doxorubicin; Drug Resistance; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Survival Analysis | 2007 |
Phase II trial of thalidomide with chemotherapy and as maintenance therapy for patients with poor prognosis small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Disease Progression; Etoposide; Female; Humans; Lung Neoplasms; Male; Prognosis; Survival Rate; Thalidomide; Treatment Outcome | 2008 |
A randomized, phase II trial of two dose levels of temsirolimus (CCI-779) in patients with extensive-stage small-cell lung cancer who have responding or stable disease after induction chemotherapy: a trial of the Eastern Cooperative Oncology Group (E1500)
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Follow-Up Studies; Humans; Irinotecan; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Protein Kinase Inhibitors; Remission Induction; Sirolimus; Survival Rate; Treatment Outcome | 2007 |
Neurocognitive function in patients with small cell lung cancer : effect of prophylactic cranial irradiation.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cognition; Cognition Disorders; Combined Modality Therapy; Cranial Irradiation; Dose-Response Relationship, Radiation; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Psychomotor Performance; Speech | 2008 |
Randomised phase II trial of irinotecan plus cisplatin vs irinotecan, cisplatin plus etoposide repeated every 3 weeks in patients with extensive-disease small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Irinotecan; Lung Neoplasms; Male; Middle Aged; Prospective Studies; Survival Rate | 2008 |
Randomized phase II Study of carboplatin and etoposide with or without the bcl-2 antisense oligonucleotide oblimersen for extensive-stage small-cell lung cancer: CALGB 30103.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Disease-Free Survival; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Multivariate Analysis; Neoplasm Staging; Odds Ratio; Thionucleotides; Treatment Outcome | 2008 |
A threefold dose intensity treatment with ifosfamide, carboplatin, and etoposide for patients with small cell lung cancer: a randomized trial.
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Female; Hematologic Diseases; Humans; Ifosfamide; Incidence; Lung Neoplasms; Male; Middle Aged; Odds Ratio; Prognosis; Research Design; Survival Analysis; Treatment Outcome | 2008 |
A phase III randomised study of concomitant induction radiochemotherapy testing two modalities of radiosensitisation by cisplatin (standard versus daily) for limited small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Radiation-Sensitizing Agents | 2008 |
Combination chemotherapy for non-small cell lung cancer with doxorubicin and mitomycin or cisplatin and etoposide.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Mitomycins | 1984 |
Combination chemotherapy in small cell lung carcinoma. A randomized study of two intensive regimens.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Vincristine | 1984 |
VP-16-213 in combination chemotherapy with chest irradiation for small-cell lung cancer: a randomized trial of the Piedmont Oncology Association.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Podophyllotoxin; Vincristine | 1984 |
Chemoimmunotherapy of small cell bronchogenic carcinoma with VP-16-213, ifosfamide, vincristine, adriamycin, and Corynebacterium parvum.
Topics: Adult; Aged; Antineoplastic Agents; Bacterial Vaccines; Brain; Carcinoma, Small Cell; Clinical Trials as Topic; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Propionibacterium acnes; Vincristine | 1981 |
An evaluation of low-dose cisplatin as part of combined modality therapy of limited small cell lung cancer.
Topics: Adult; Aged; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Time Factors; Vincristine | 1981 |
Combination chemotherapy for small cell carcinoma of the lung: continuous versus alternating non-cross-resistant combinations.
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Etoposide; Female; Humans; Leukopenia; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Procarbazine; Vincristine | 1982 |
VP-16-213 (etoposide): the mandrake root from Issyk-Kul.
Topics: Animals; Breast Neoplasms; Carcinoma, Small Cell; Cell Cycle; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Dysgerminoma; Etoposide; Female; Humans; Leukemia; Lung Neoplasms; Lymphoma; Mice; Podophyllotoxin | 1982 |
Phase III study of CCNU, cyclophosphamide, adriamycin, vincristine, and VP-16 in small-cell carcinoma of the lung.
Topics: Aged; Antineoplastic Agents; Carcinoma, Small Cell; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Lomustine; Lung Neoplasms; Male; Middle Aged; Probability; Vincristine | 1982 |
Doxorubicin, Cyclophosphamide and VP16-213 (ACE) in the treatment of small cell lung cancer.
Topics: Adult; Aged; Brain Neoplasms; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1982 |
Parenteral intravenous nutrition (PIVN) as an adjunct to chemotherapy in small cell anaplastic lung carcinoma.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Bone Marrow; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Gastrointestinal Diseases; Humans; Ifosfamide; Lung Neoplasms; Male; Methotrexate; Middle Aged; Parenteral Nutrition; Procarbazine; Random Allocation; Vincristine | 1981 |
[Short-term induction and cyclic maintenance therapy in inoperable small cell bronchial cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Middle Aged; Prognosis; Vincristine | 1982 |
Chemotherapy of metastatic non-small cell bronchogenic carcinoma.
Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Doxorubicin; Drug Therapy, Combination; Etoposide; Humans; Lung Neoplasms; Prognosis; Vinblastine; Vindesine | 1983 |
Lack of potentiation of vincristine-induced neurotoxicity by VP-16-213.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nervous System Diseases; Podophyllotoxin; Random Allocation; Vincristine | 1983 |
Early crossover of induction chemotherapy in small cell lung carcinoma.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Procarbazine; Prospective Studies; Vincristine | 1983 |
Continuous versus alternating combination chemotherapy for advanced small cell carcinoma of the lung.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Etoposide; Follow-Up Studies; Humans; Lomustine; Lung Neoplasms; Neoplasm Metastasis; Prognosis; Vincristine | 1983 |
Treatment of extensive stage small cell bronchogenic carcinoma. Effects of variation in intensity of induction chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Postoperative Complications; Prognosis; Vincristine | 1983 |
Trimethoprim/sulfamethoxazole versus placebo: a double-blind comparison of infection prophylaxis in patients with small cell carcinoma of the lung.
Topics: Adult; Aged; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Carcinoma, Small Cell; Clinical Trials as Topic; Cyclophosphamide; Double-Blind Method; Doxorubicin; Etoposide; Female; Humans; Leukocyte Count; Lung Neoplasms; Male; Middle Aged; Random Allocation; Sulfamethoxazole; Trimethoprim | 1983 |
Combined modality treatment of extensive small cell lung cancer: a Southwest Oncology Group study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Brain Neoplasms; Carcinoma, Small Cell; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Etoposide; Humans; Leukopenia; Lung Neoplasms; Methotrexate; Random Allocation; Stomatitis; Vincristine | 1984 |
A phase I study of cisplatin, etoposide, and paclitaxel in small cell lung cancer: a University of Colorado Cancer Center study.
Topics: Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Hematologic Diseases; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Paclitaxel; Premedication; Taxoids; Treatment Outcome | 1995 |
[Induction chemotherapy followed by adjuvant surgery (IC-AS) in patients with stage I-II small cell lung cancer (SCLC)].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Nimustine; Salvage Therapy; Vincristine | 1995 |
[Five-day continuous intravenous infusion of cisplatin and etoposide for extensive stage small cell lung cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged | 1995 |
A prospective randomised study in limited disease small cell carcinoma--doxorubicin and vincristine plus either cyclophosphamide or etoposide.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Prospective Studies; Survival Rate; Vincristine | 1995 |
A randomised trial of three or six courses of etoposide cyclophosphamide methotrexate and vincristine or six courses of etoposide and ifosfamide in small cell lung cancer (SCLC). II: Quality of life. Medical Research Council Lung Cancer Working Party.
Topics: Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Anxiety; Carcinoma, Small Cell; Cyclophosphamide; Depression; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Female; Humans; Ifosfamide; Infusions, Intravenous; Lung Neoplasms; Male; Medical Records; Methotrexate; Middle Aged; Nausea; Palliative Care; Patient Compliance; Quality of Life; Self-Assessment; Vincristine; Vomiting | 1993 |
Dose-intensive chemotherapy in extensive-stage small cell lung cancer.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Middle Aged; Recombinant Proteins; Survival Rate; Vincristine | 1994 |
[Chemotherapy for small cell lung cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Recombinant Proteins; Vincristine | 1993 |
Phase II trial of megestrol in the supportive care of patients receiving dose-intensive chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Etoposide; Female; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Megestrol; Middle Aged; Mitomycins; Vincristine; Weight Loss | 1994 |
Positively selected autologous blood CD34+ cells and unseparated peripheral blood progenitor cells mediate identical hematopoietic engraftment after high-dose VP16, ifosfamide, carboplatin, and epirubicin.
Topics: Adult; Antigens, CD; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Bleomycin; Blood Transfusion, Autologous; Breast Neoplasms; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Epirubicin; Etoposide; Feasibility Studies; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Neoplasms; Predictive Value of Tests; Vincristine | 1994 |
Phase I and pharmacologic study of irinotecan and etoposide with recombinant human granulocyte colony-stimulating factor support for advanced lung cancer.
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Diarrhea; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Half-Life; Humans; Irinotecan; Leukopenia; Lung Neoplasms; Male; Middle Aged; Recombinant Proteins; Remission Induction; Thrombocytopenia | 1994 |
Multicyclic, dose-intensive chemotherapy supported by sequential reinfusion of hematopoietic progenitors in whole blood.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion, Autologous; Carboplatin; Carcinoma, Small Cell; Cause of Death; Combined Modality Therapy; Etoposide; Feasibility Studies; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Ifosfamide; Leukapheresis; Lung Neoplasms; Male; Middle Aged; Pilot Projects; Platelet Transfusion | 1995 |
Use of high-dose etoposide/ifosfamide/carboplatin/epirubicin and peripheral blood progenitor cell transplantation in limited-disease small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Epirubicin; Etoposide; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Ifosfamide; Lung Neoplasms; Middle Aged; Survival Analysis | 1995 |
[Radiotherapy of limited pulmonary microcytoma in current clinical practice].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nimustine; Patient Selection; Peplomycin; Radiotherapy Dosage; Survival Rate; Time Factors; Treatment Outcome; Vinblastine; Vincristine | 1994 |
Can cytotoxic dose-intensity be increased by using granulocyte colony-stimulating factor? A randomized controlled trial of lenograstim in small-cell lung cancer.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Ifosfamide; Lenograstim; Leukocyte Count; Lung Neoplasms; Male; Middle Aged; Neutropenia; Neutrophils; Prognosis; Recombinant Proteins; Survival Rate; Vincristine | 1995 |
Oral etoposide and carboplatin. Effective therapy for elderly patients with small cell lung cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Etoposide; Female; Frail Elderly; Humans; Lung Neoplasms; Male; Middle Aged; Palliative Care; Remission Induction; Survival Rate | 1995 |
Quality versus quantity of life in the treatment of patients with advanced small-cell lung cancer? A randomized phase III comparison of weekly carboplatin and teniposide versus cisplatin, adriamycin, etoposide alternating with cyclophosphamide, methotrexa
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Palliative Care; Prospective Studies; Quality of Life; Surveys and Questionnaires; Survival Rate; Teniposide; Vincristine | 1995 |
[Clinical study of recombinant human granulocyte colony-stimulating factor (RHG-CSF) on leucopenia induced by chemotherapy with CE regimen on lung cancer patients].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cross-Over Studies; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Neutropenia; Recombinant Proteins | 1994 |
A phase I study of ifosfamide/carboplatin/etoposide/paclitaxel in advanced lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cohort Studies; Drug Tolerance; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Ifosfamide; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Neutropenia; Paclitaxel; Remission Induction; Thrombocytopenia | 1995 |
Etoposide phosphate or etoposide with cisplatin in the treatment of small cell lung cancer: randomized phase II trial.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Organophosphorus Compounds; Treatment Outcome | 1995 |
Cisplatin plus etoposide with and without ifosfamide in extensive small-cell lung cancer: a Hoosier Oncology Group study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; Humans; Ifosfamide; Injections, Intravenous; Lung Neoplasms; Male; Middle Aged; Proportional Hazards Models; Radiography; Regression Analysis; Survival Rate | 1995 |
Single fraction prophylactic cranial irradiation for small cell carcinoma of the lung.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Carcinoma, Small Cell; Cisplatin; Cognition; Combined Modality Therapy; Cranial Irradiation; Etoposide; Female; Follow-Up Studies; Humans; Ifosfamide; Lung Neoplasms; Male; Memory; Psychomotor Performance; Radiotherapy Dosage; Remission Induction; Retrospective Studies; Survival Rate; Vincristine | 1995 |
Phase II study of ifosfamide, carboplatin, and oral etoposide chemotherapy for extensive-disease small-cell lung cancer: an Eastern Cooperative Oncology Group pilot study.
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Pilot Projects; Remission Induction; Survival Rate | 1995 |
Clinical and in vitro effects of recombinant human erythropoietin in patients receiving intensive chemotherapy for small-cell lung cancer.
Topics: Adult; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Colony-Forming Units Assay; Drug Administration Schedule; Erythrocyte Transfusion; Erythropoietin; Etoposide; Female; Granulocytes; Hemoglobin A; Humans; Ifosfamide; Iron; Leukocyte Count; Lung Neoplasms; Macrophages; Male; Mesna; Middle Aged; Platelet Count; Platelet Transfusion; Recombinant Proteins; Vincristine | 1995 |
Chemoradiotherapy with or without granulocyte-macrophage colony-stimulating factor in the treatment of limited-stage small-cell lung cancer: a prospective phase III randomized study of the Southwest Oncology Group.
Topics: Adult; Aged; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Etoposide; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Neutropenia; Prospective Studies; Thrombocytopenia | 1995 |
Combination chemotherapy with cyclophosphamide, vincristine, cisplatin and etoposide (COPE) combined with radiotherapy for small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Drug Combinations; Etoposide; Humans; Leukopenia; Life Tables; Lung Neoplasms; Middle Aged; Radiotherapy, Adjuvant; Retrospective Studies; Survival Analysis; Vincristine | 1995 |
Schedule dependency of 21-day oral versus 3-day intravenous etoposide in combination with intravenous cisplatin in extensive-stage small-cell lung cancer: a randomized phase III study of the Cancer and Leukemia Group B.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Carcinoma, Small Cell; Chi-Square Distribution; Cisplatin; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Proportional Hazards Models; Remission Induction; Survival Rate; United States | 1995 |
Prospective multimodality treatment of SCLC--experience during the past 18 years.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Methotrexate; Pneumonectomy; Postoperative Care; Prednisone; Procarbazine; Radiotherapy Dosage; Vincristine | 1995 |
Recombinant granulocyte colony stimulating factor reduces the infectious complications of cytotoxic chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Carcinoma, Small Cell; Cyclophosphamide; Double-Blind Method; Doxorubicin; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Middle Aged; Neutropenia; Recombinant Proteins | 1993 |
Combined-modality treatment of small-cell lung cancer: randomized comparison of three induction chemotherapies followed by maintenance chemotherapy with or without radiotherapy to the chest. Swiss Group for Clinical Cancer Research (SAKK).
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Contraindications; Cranial Irradiation; Cyclophosphamide; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Prospective Studies; Radiotherapy; Radiotherapy, Adjuvant; Regression Analysis; Remission Induction; Switzerland; Thorax; Vincristine | 1994 |
Phase II study of daily oral etoposide plus ifosfamide plus cisplatin for previously treated recurrent small-cell lung cancer: a Hoosier Oncology Group Trial.
Topics: Administration, Oral; Aged; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Hematologic Diseases; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Remission Induction; Survival Analysis | 1995 |
Phase II study of paclitaxel in patients with extensive-disease small-cell lung cancer: an Eastern Cooperative Oncology Group study.
Topics: Adult; Aged; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Female; Humans; Infusions, Intravenous; Leukopenia; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Remission Induction; Salvage Therapy; Survival Analysis | 1995 |
Phase II randomized study of cisplatin plus etoposide phosphate or etoposide in the treatment of small-cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Organophosphorus Compounds; Survival Analysis | 1995 |
Early versus late alternating chemotherapy in small-cell lung cancer. Swiss Group for Clinical Cancer Research (SAKK).
Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Patient Acceptance of Health Care; Quality of Life; Remission Induction; Survivors; Treatment Outcome; Vincristine | 1995 |
[Pilot study of sequential chemotherapy and radiation therapy using of liniac and fast neutron for limited small cell lung cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Fast Neutrons; Female; Humans; Lung Neoplasms; Male; Middle Aged; Pilot Projects; Radiotherapy Dosage; Vincristine | 1995 |
Combination chemotherapy with cyclophosphamide, epirubicin and etoposide in small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Epirubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged | 1994 |
Carboplatin and etoposide in extensive small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Survival Analysis; Treatment Outcome | 1994 |
Priming low-dose chest radiotherapy followed by chemotherapy for limited small-cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Radiotherapy Dosage | 1994 |
Cisplatin and etoposide versus cyclophosphamide, epirubicin and vincristine in small cell lung cancer: a randomised study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Epirubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Vincristine | 1994 |
Ifosfamide, doxorubicin, vincristine, and etoposide in small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Pilot Projects; Survival Analysis; Vincristine | 1995 |
Induction chemotherapy with ifosfamide, etoposide, and anthracycline for small cell lung cancer: experience of the European Lung Cancer Working Party.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Doxorubicin; Epirubicin; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Prospective Studies; Survival Analysis | 1995 |
The place of ifosfamide in chemotherapy of small cell lung cancer: the Eastern Cooperative Oncology Group experience and a selected literature update.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Ifosfamide; Lung Neoplasms; Salvage Therapy; Teniposide; Vincristine | 1995 |
Hoosier Oncology Group studies in extensive and recurrent small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Survival Analysis | 1995 |
A phase II study of recombinant interferon-gamma following combination chemotherapy for patients with extensive small cell lung cancer. CALGB.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Infusions, Intravenous; Interferon-gamma; Lung Neoplasms; Male; Middle Aged; Recombinant Proteins; Survival Analysis; Treatment Outcome | 1995 |
Interdigitating versus concurrent chemotherapy and radiotherapy for limited small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Recurrence, Local; Remission Induction; Treatment Failure; Vincristine | 1995 |
[Small cell lung carcinoma: role of thoracic irradiation and its timing in relation to chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Follow-Up Studies; Humans; Lung Neoplasms; Radiotherapy Dosage; Survival Rate; Time Factors; Vincristine | 1994 |
Small cell carcinoma of the cervix treated with concurrent radiotherapy, cisplatin, and etoposide.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Humans; Middle Aged; Uterine Cervical Neoplasms | 1995 |
Prospective randomized comparison of high-dose and standard-dose etoposide and cisplatin chemotherapy in patients with extensive-stage small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Etoposide; Female; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Proportional Hazards Models; Prospective Studies; Remission Induction; Survival Rate; Thrombocytopenia; Weight Loss | 1994 |
[Phase II study of a continuous five-day intravenous infusion of cisplatin and etoposide with concurrent chest radiation therapy in limited stage small cell lung cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Etoposide; Female; Humans; Infusions, Intravenous; Leukopenia; Lung Neoplasms; Male; Middle Aged; Prognosis | 1994 |
Prophylactic cranial irradiation in complete responders with small-cell lung cancer: analysis of the Mayo Clinic and North Central Cancer Treatment Group data bases.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Cisplatin; Cranial Irradiation; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Multivariate Analysis; Prognosis; Prospective Studies; Survival Rate; Thoracic Neoplasms; Vincristine | 1994 |
Concurrent cisplatin-etoposide chemotherapy plus thoracic radiotherapy for limited-stage small cell lung cancer. Japanese Lung Cancer Chemotherapy Group in Japanese Clinical Oncology Group.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Drug Administration Schedule; Etoposide; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Radiotherapy; Remission Induction; Treatment Outcome | 1994 |
A randomized clinical trial in bronchogenic small-cell carcinoma evaluating alternating maintenance therapy of vincristine, adriamycin, procarbazine, and etoposide (VAPE) with cyclophosphamide, CCNU, and methotrexate (CCM) versus CCM maintenance alone in
Topics: Aged; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Mitomycin; Procarbazine; Remission Induction; Vinblastine; Vincristine | 1994 |
Dose-ranging study of recombinant human granulocyte-macrophage colony-stimulating factor in small-cell lung carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Infections; Lung Neoplasms; Male; Middle Aged; Neutropenia; Remission Induction; Survival Analysis | 1994 |
[Phase I/II study of a combination regimen composed of cisplatin, carboplatin and etoposide against small cell lung cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged | 1994 |
Randomized comparison of etoposide-cisplatin vs. etoposide-carboplatin and irradiation in small-cell lung cancer. A Hellenic Co-operative Oncology Group study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Etoposide; Female; Follow-Up Studies; Greece; Humans; Lung Neoplasms; Male; Middle Aged; Remission Induction; Survival Rate | 1994 |
High dose-intense chemotherapy alone or in combination with interleukin-2 for small cell lung cancer: a pilot study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cohort Studies; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Drug Synergism; Etoposide; Female; Humans; Immunotherapy; Infusions, Intravenous; Interleukin-2; Lung Neoplasms; Lymphocyte Count; Male; Middle Aged; Pilot Projects; Vincristine | 1994 |
[CAV-PVP chemotherapy and sequential thoracic irradiation (TI) for patients with limited (LD) small cell lung cancer (SCLC)].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Radiotherapy Dosage; Vincristine | 1993 |
Can long-term survival be improved in patients with small-cell lung cancer (SCLC) and good performance status? Medical Research Council Lung Cancer Working Party.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Humans; Lung Neoplasms; Proportional Hazards Models; Radiotherapy Dosage; Radiotherapy, High-Energy; Survival Analysis; Survival Rate | 1994 |
A randomized trial of two etoposide schedules in small-cell lung cancer: the influence of pharmacokinetics on efficacy and toxicity.
Topics: Adult; Aged; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Regression Analysis; Survival Analysis; Treatment Outcome | 1994 |
[Small cell bronchial cancer. Comparison of results of weekly polychemotherapy using multiple drugs with standard chemotherapy. European Lung Cancer Working Party].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Prognosis; Survival Rate; Vincristine; Vindesine | 1994 |
Cisplatin/etoposide versus carboplatin/etoposide chemotherapy and irradiation in small cell lung cancer: a randomized phase III study. Hellenic Cooperative Oncology Group for Lung Cancer Trials.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Remission Induction; Survival Analysis | 1994 |
Etoposide/vincristine-based chemotherapy with or without carboplatin in extensive-stage small cell lung cancer: a prospective randomized phase III trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Prospective Studies; Remission Induction; Survival Analysis; Vincristine | 1994 |
Limited disease small cell lung cancer: alternating combination of doxorubicin, etoposide, ifosfamide and hyperfractionated radiotherapy. Final results of a multicentric pilot study for the Groupe Lyonnias d'Oncologie Thoracique (GLOT).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Pilot Projects; Radiotherapy | 1993 |
Carboplatin plus epirubicin plus VP-16, concurrent 'split course' radiotherapy and adjuvant surgery for limited small cell lung cancer. Gruppo Oncologico Centro-Sud-Isole (GOCSI).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Digestive System Diseases; Epirubicin; Etoposide; Humans; Kidney Diseases; Life Tables; Lung Neoplasms; Middle Aged; Neoplasm Recurrence, Local; Pneumonectomy; Survival Analysis | 1994 |
Randomized trial comparing weekly versus 3-week chemotherapy in small-cell lung cancer: a Cancer Research Campaign trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Remission Induction; Survival Rate; Vincristine | 1994 |
Alternating radiotherapy and chemotherapy in limited small cell lung cancer: the IGR protocols. French FNCLCC Lung Cancer Study Group.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Radiotherapy Dosage; Remission Induction; Survival Rate; Treatment Failure | 1994 |
Cisplatin-VP16 alternating with cyclophosphamide-epirubicin versus cyclophosphamide-epirubicin-vincristine in small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Epirubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Survival Rate; Vincristine | 1993 |
Urinary-derived monocyte-colony stimulating factor (P-100) following treatment with carboplatin and etoposide in small cell lung cancer (SCLC).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Remission Induction; Survival Rate; Treatment Outcome | 1993 |
Phase II trial of oral etoposide plus cisplatin in extensive stage small cell carcinoma of the lung: an Eastern Cooperative Oncology Group study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Thrombocytopenia; Treatment Outcome | 1994 |
Prolonged administration of low dose infusional etoposide in patients with advanced malignancies. A phase I/II study.
Topics: Adult; Bone Marrow; Carcinoma, Small Cell; Drug Administration Schedule; Drug Tolerance; Erythrocyte Transfusion; Etoposide; Female; Humans; Infusions, Parenteral; Lung Neoplasms; Lymphoma, Non-Hodgkin; Male; Middle Aged; Neoplasms; Platelet Transfusion | 1994 |
CVM versus ACE in the treatment of small cell lung cancer.
Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carboplatin; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Infant, Newborn; Infections; Leukopenia; Lung Neoplasms; Male; Methotrexate; Middle Aged; Thrombocytopenia; Treatment Outcome; Vinblastine | 1993 |
Initial chemotherapeutic doses and survival in patients with limited small-cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Prospective Studies | 1993 |
A randomised trial of three or six courses of etoposide cyclophosphamide methotrexate and vincristine or six courses of etoposide and ifosfamide in small cell lung cancer (SCLC). I: Survival and prognostic factors. Medical Research Council Lung Cancer Wor
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cause of Death; Chi-Square Distribution; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Female; Humans; Ifosfamide; Infusions, Intravenous; Lung Neoplasms; Male; Methotrexate; Middle Aged; Prognosis; Proportional Hazards Models; Regression Analysis; Survival Analysis; Survival Rate; Treatment Outcome; Vincristine | 1993 |
Sequencing and schedule effects of cisplatin plus etoposide in small-cell lung cancer: results of a North Central Cancer Treatment Group randomized clinical trial.
Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Etoposide; Female; Humans; Infusions, Intravenous; Injections, Intravenous; Lung Neoplasms; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Survival Analysis; Treatment Outcome | 1994 |
Testing the possible non-cross resistance of two equipotent combination chemotherapy regimens against small-cell lung cancer: a phase II study of the EORTC Lung Cancer Cooperative Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Resistance; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Mesna; Middle Aged; Prognosis; Vincristine | 1993 |
Interleukin-2 activity in patients with extensive small-cell lung cancer: a phase II trial of Cancer and Leukemia Group B.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Interleukin-2; Lung Neoplasms; Male; Middle Aged; Prospective Studies | 1993 |
No effect of an antiaggregant treatment with aspirin in small cell lung cancer treated with CCAVP16 chemotherapy. Results from a randomized clinical trial of 303 patients. The "Petites Cellules" Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lomustine; Lung Neoplasms; Male; Melphalan; Middle Aged; Platelet Aggregation; Prednisone; Survival Rate | 1993 |
Phase I/II trial of etoposide and carboplatin in extensive small-cell lung cancer. A report from the Cancer and Leukemia Group B.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Survival Analysis | 1993 |
A randomized study comparing cyclophosphamide, doxorubicin, vincristine (CAV) with cyclophosphamide, etoposide, vincristine, methotrexate (CEVM) in patients with small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Vincristine | 1993 |
Tumour markers for prediction of survival and monitoring of remission in small cell lung cancer.
Topics: Adult; Aged; Analysis of Variance; Biomarkers, Tumor; Carcinoembryonic Antigen; Carcinoma, Small Cell; Chromogranin A; Chromogranins; Etoposide; Female; Humans; L-Lactate Dehydrogenase; Lung Neoplasms; Male; Middle Aged; Phosphopyruvate Hydratase; Predictive Value of Tests; Prognosis; Recurrence | 1993 |
Alternating chemotherapy and twice-daily thoracic radiotherapy in limited-stage small-cell lung cancer: a pilot study of the Eastern Cooperative Oncology Group.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Pilot Projects | 1993 |
A randomised study of bolus vs continuous pump infusion of ifosfamide and doxorubicin with oral etoposide for small cell lung cancer.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Ifosfamide; Infusion Pumps; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Quality of Life | 1993 |
Combination chemotherapy with or without thoracic radiotherapy in limited-stage small-cell lung cancer: a randomized trial of the Southeastern Cancer Study Group.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Prospective Studies; Radiotherapy; Survival Analysis; Thorax; Treatment Failure; Vincristine | 1993 |
Maintenance chemotherapy in small-cell lung cancer: long-term results of a randomized trial. European Organization for Research and Treatment of Cancer Lung Cancer Cooperative Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Regression Analysis; Survival Analysis; Treatment Outcome | 1993 |
Granulocyte-macrophage colony-stimulating factor increases dose intensity of chemotherapy in small cell lung cancer. Relationship between clinical results, peripheral blood cell modifications, and bone marrow kinetics.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cell Count; Cisplatin; Dose-Response Relationship, Drug; Epirubicin; Etoposide; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Middle Aged; Treatment Outcome | 1993 |
Predictors of survival following relapse or progression of small cell lung cancer. Southwest Oncology Group Study 8605 report and analysis of recurrent disease data base.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Cytarabine; Drug Administration Schedule; Ethylnitrosourea; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Survival Rate; Thiotepa; Vincristine | 1993 |
Pilot study of cyclophosphamide-doxorubicin-vincristine-cisplatin-etoposide hybrid chemotherapy in small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Pilot Projects; Remission Induction; Survival Rate; Vincristine | 1993 |
Combination chemotherapy for small cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Malaysia; Male; Middle Aged; Prognosis; Prospective Studies; Quality of Life | 1993 |
A randomised clinical study of verapamil in addition to combination chemotherapy in small cell lung cancer. West of Scotland Lung Cancer Research Group, and the Aberdeen Oncology Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Pressure; Carcinoma, Small Cell; Doxorubicin; Drug Administration Schedule; Drug Resistance; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Survival Analysis; Verapamil; Vincristine | 1993 |
Role of recombinant interferon alfa-2a maintenance in patients with limited-stage small-cell lung cancer responding to concurrent chemoradiation: a Southwest Oncology Group study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Female; Humans; Interferon alpha-2; Interferon-alpha; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Prospective Studies; Recombinant Proteins; Remission Induction | 1995 |
Phase II study of infusional cisplatin in combination with etoposide in the treatment of small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Survival Rate | 1995 |
Dose intensification of carboplatin and etoposide as first-line combination chemotherapy in small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cranial Irradiation; Etoposide; Humans; Lung Neoplasms; Middle Aged; Pilot Projects | 1995 |
Randomized double-blind placebo-controlled trial of cisplatin and etoposide plus megestrol acetate/placebo in extensive-stage small-cell lung cancer: a North Central Cancer Treatment Group study.
Topics: Anorexia; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cachexia; Carcinoma, Small Cell; Cisplatin; Double-Blind Method; Drug Administration Schedule; Etoposide; Humans; Lung Neoplasms; Megestrol; Megestrol Acetate; Pain Measurement; Quality of Life; Survival Analysis; Survival Rate; Thromboembolism | 1996 |
Predicting etoposide toxicity: relationship to organ function and protein binding.
Topics: Adult; Aged; Carcinoma, Small Cell; Chromatography, High Pressure Liquid; Creatinine; Etoposide; Female; Half-Life; Hematologic Diseases; Humans; Kidney Function Tests; Leukocyte Count; Liver Function Tests; Lung Neoplasms; Male; Middle Aged; Neutrophils; Predictive Value of Tests; Protein Binding; Regression Analysis | 1996 |
Randomised trial of four-drug vs less intensive two-drug chemotherapy in the palliative treatment of patients with small-cell lung cancer (SCLC) and poor prognosis. Medical Research Council Lung Cancer Working Party.
Topics: Activities of Daily Living; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Etoposide; Female; Humans; Male; Methotrexate; Middle Aged; Palliative Care; Patient Compliance; Quality of Life; Stress, Psychological; Survival Analysis; Vincristine | 1996 |
Increasing and planned dose intensity of doxorubicin, cyclophosphamide and etoposide (ACE) by adding recombinant human methionyl granulocyte colony-stimulating factor (G-CSF; filgrastim) in the treatment of small cell lung cancer (SCLC). Medical Research
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Middle Aged; Neutropenia; Recombinant Proteins | 1995 |
Desmoplastic small round cell tumors: results of a four-drug chemotherapy regimen in five adult patients.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Male; Peritoneal Neoplasms; Salvage Therapy; Treatment Outcome | 1996 |
Infusion cisplatin chemotherapy and hyperfractionated thoracic radiotherapy for small-cell lung cancer.
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Cause of Death; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Etoposide; Follow-Up Studies; Humans; Infusions, Intravenous; Leukopenia; Lung; Lung Neoplasms; Neoplasm Staging; Radiation Pneumonitis; Remission Induction; Survival Rate; Thrombocytopenia | 1996 |
Patients with limited-stage small-cell lung cancer treated with concurrent twice-daily chest radiotherapy and etoposide/cisplatin followed by cyclophosphamide, doxorubicin, and vincristine.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Cause of Death; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Radiotherapy Dosage; Remission Induction; Vincristine | 1996 |
Dose escalation study of carboplatin with fixed-dose etoposide plus granulocyte-colony stimulating factor in patients with small cell lung carcinoma. A study of the Lung Cancer Study Group of West Japan.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Dose-Response Relationship, Drug; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Middle Aged; Survival Analysis; Thrombocytopenia | 1996 |
Prospective evaluation of the feasibility of cisplatin-based chemotherapy for elderly lung cancer patients with normal organ functions.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Etoposide; Feasibility Studies; Female; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Neoplasms, Multiple Primary; Neutropenia; Prospective Studies; Remission Induction; Vindesine | 1995 |
Paclitaxel, carboplatin, and extended schedule etoposide in the treatment of small cell lung carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Outpatients; Paclitaxel; Survival Analysis | 1996 |
Point mutations of the topoisomerase IIalpha gene in patients with small cell lung cancer treated with etoposide.
Topics: Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Base Sequence; Carcinoma, Small Cell; Codon; DNA Topoisomerases, Type II; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Sequence Analysis, DNA | 1996 |
Paclitaxel in lung cancer: 1-hour infusions given alone or in combination chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Etoposide; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Paclitaxel; Remission Induction | 1995 |
Phase II study of intensive CEV (carboplatin, epirubicin and VP-16) plus G-CSF (granulocyte-colony stimulating factor) in extensive small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Carmustine; Cyclophosphamide; Epirubicin; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Middle Aged | 1995 |
Therapeutic monitoring of continuous infusion etoposide in small-cell lung cancer.
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Small Cell; Drug Monitoring; Etoposide; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Time Factors | 1996 |
A randomised trial of low-dose/high-frequency chemotherapy as palliative treatment of poor-prognosis small-cell lung cancer: a Cancer research Campaign trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Palliative Care; Prognosis; Quality of Life; Vincristine | 1996 |
Analysis of thrombocytopenia due to carboplatin combined with etoposide in elderly patients with lung cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Etoposide; Evaluation Studies as Topic; Female; Humans; Lung Neoplasms; Male; Retrospective Studies; Thrombocytopenia | 1996 |
[Clinical trial of oral etoposide in the treatment of malignancies].
Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Child; Etoposide; Female; Humans; Lung Neoplasms; Lymphoma; Male; Middle Aged; Ovarian Neoplasms; Prospective Studies | 1995 |
Randomized trial comparing induction chemotherapy versus induction chemotherapy followed by maintenance chemotherapy in small-cell lung cancer. European Lung Cancer Working Party.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Disease-Free Survival; Doxorubicin; Epirubicin; Etoposide; Europe; Female; Humans; Ifosfamide; Karnofsky Performance Status; Lung Neoplasms; Male; Middle Aged; Multivariate Analysis; Remission Induction; Survival Rate; Vindesine | 1996 |
Phase II study of topotecan in patients with extensive-stage small-cell carcinoma of the lung: an Eastern Cooperative Oncology Group Trial.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Neutropenia; Remission Induction; Salvage Therapy; Survival Rate; Topotecan; United States | 1996 |
Intensified VICE regimen may improve SCLC survival.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Disease-Free Survival; Etoposide; Humans; Ifosfamide; Lung Neoplasms; Vincristine | 1996 |
Pilot study of ambulatory infusional delivery of a multidrug regimen: ifosfamide, carboplatin and etoposide (ICE).
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Ambulatory Care; Anemia; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Etoposide; Female; Humans; Ifosfamide; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Neutropenia; Thrombocytopenia | 1996 |
Phase II study of recombinant human interleukin 3 administration following carboplatin and etoposide chemotherapy in small-cell lung cancer patients. SDZ ILE 964 (IL-3) Study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Dose-Response Relationship, Drug; Etoposide; Female; Humans; Interleukin-3; Lung Neoplasms; Male; Middle Aged; Recombinant Proteins; Thrombocytopenia | 1996 |
Comparison of oral etoposide and standard intravenous multidrug chemotherapy for small-cell lung cancer: a stopped multicentre randomised trial. Medical Research Council Lung Cancer Working Party.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Female; Humans; Injections, Intravenous; Lung Neoplasms; Male; Middle Aged; Palliative Care; Survival Analysis; Treatment Failure | 1996 |
The limits of chemotherapy dose intensification using granulocyte colony stimulating factor alone in extensive small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Feasibility Studies; Female; Granulocyte Colony-Stimulating Factor; Humans; Ifosfamide; Leukocyte Count; Lung Neoplasms; Male; Neutropenia; Prospective Studies | 1996 |
Correlation of in vitro drug sensitivity testing results with response to chemotherapy and survival: comparison of non-small cell lung cancer and small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carmustine; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Evaluation Studies as Topic; Humans; Lomustine; Lung Neoplasms; Mechlorethamine; Methotrexate; Palliative Care; Predictive Value of Tests; Prospective Studies; Specimen Handling; Survival Analysis; Treatment Outcome; Tumor Cells, Cultured; Vincristine | 1996 |
Phase I study of simultaneous dose escalation and schedule acceleration of cyclophosphamide-doxorubicin-etoposide using granulocyte colony-stimulating factor with or without antimicrobial prophylaxis in patients with small-cell lung cancer.
Topics: Antibiotic Prophylaxis; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Survival Analysis; Treatment Outcome | 1996 |
Interferon alpha-2a and combined chemotherapy as first line treatment in SCLC patients: a randomized trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Drug Administration Schedule; Drug Synergism; Epirubicin; Etoposide; Female; Humans; Ifosfamide; Interferon alpha-2; Interferon-alpha; Lung Neoplasms; Male; Middle Aged; Recombinant Proteins; Remission Induction | 1996 |
A phase I/II trial of etoposide and cisplatin in extensive small cell lung cancer: a cancer and leukemia group B study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged | 1996 |
Phase I/II study of combination chemotherapy with cisplatin, carboplatin and etoposide in small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Middle Aged | 1996 |
Dose-escalation study of oral etoposide and carboplatin in patients with advanced lung cancer.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged | 1996 |
Sequential high-dose ICE chemotherapy with circulating progenitor cells (CPC) in small cell lung cancer: an EBMT study.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Etoposide; Europe; Female; Hematopoietic Stem Cell Transplantation; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged | 1996 |
Standard versus alternating non-cross-resistant chemotherapy in extensive small cell lung cancer: an EORTC Phase III trial.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Blood Cells; Carboplatin; Carcinoma, Small Cell; Cyclophosphamide; Disease Progression; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Mesna; Middle Aged; Multivariate Analysis; Survival Analysis; Vincristine | 1996 |
Phase I study of chemotherapy with carboplatin, epirubicin, and escalating dose of VP-16 with G-CSF support in extensive small cell lung cancer.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carboplatin; Carcinoma, Small Cell; Cause of Death; Dose-Response Relationship, Drug; Drug Tolerance; Epirubicin; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Middle Aged; Neutropenia; Sepsis; Thrombocytopenia | 1996 |
Etoposide phosphate infusion with therapeutic drug monitoring in combination with carboplatin dosed by area under the curve: a cancer research campaign phase I/II committee study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carboplatin; Carcinoma, Small Cell; Drug Monitoring; Etoposide; Feasibility Studies; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Organophosphorus Compounds; Prodrugs | 1996 |
Clinical studies with etoposide phosphate.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Hematologic Diseases; Humans; Lung Neoplasms; Male; Middle Aged; Organophosphorus Compounds; Remission Induction | 1996 |
Combinations of paclitaxel and etoposide in the treatment of lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Drug Screening Assays, Antitumor; Etoposide; Humans; Lung Neoplasms; Middle Aged; Paclitaxel; Tumor Cells, Cultured | 1996 |
Paclitaxel, carboplatin, and oral etoposide in the treatment of small cell lung cancer.
Topics: Administration, Oral; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Paclitaxel; Survival Rate; Treatment Outcome | 1996 |
Phase I study of cisplatin, etoposide, and paclitaxel in patients with extensive-stage small cell lung cancer: a University of Colorado Cancer Center study.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neutropenia; Paclitaxel; Survival Rate; Thrombocytopenia | 1996 |
The North American experience with paclitaxel combined with cisplatin or carboplatin in lung cancer.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Lung Neoplasms; Neutropenia; Paclitaxel; Thrombocytopenia; Treatment Outcome | 1996 |
CODE chemotherapy with and without granulocyte colony-stimulating factor in small-cell lung cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Middle Aged; Survival Analysis; Vincristine | 1997 |
[Treatment of broncho-pulmonary cancer using carboplatin/etoposide: survival analysis].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Retrospective Studies; Survival Analysis | 1996 |
Phase I trial of etoposide, carboplatin, and GM-CSF in extensive small-cell lung cancer: a Cancer and Leukemia Group B study (CALGB 8832).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Middle Aged; Remission Induction; Survival Analysis | 1997 |
Adjunctive interferon-alpha-2c in stage IIIB/IV small-cell lung cancer: a phase III trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Interferon Type I; Lung Neoplasms; Male; Middle Aged; Recombinant Proteins; Remission Induction; Survival Rate; Vincristine | 1997 |
Initial versus delayed accelerated hyperfractionated radiation therapy and concurrent chemotherapy in limited small-cell lung cancer: a randomized study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Radiotherapy Dosage; Survival Analysis | 1997 |
Dose-intense therapy with etoposide, ifosfamide, cisplatin, and epirubicin (VIP-E) in 100 consecutive patients with limited- and extensive-disease small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Carboplatin; Carcinoma, Small Cell; Cardiovascular Diseases; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Epirubicin; Etoposide; Feasibility Studies; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pneumonectomy; Remission Induction; Survival Analysis; Transplantation Conditioning; Treatment Outcome | 1997 |
Ifosfamide, cisplatin and etoposide (ICE) combined chemotherapy with recombinant human granulocyte colony-stimulating factor support in small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Feasibility Studies; Female; Granulocyte Colony-Stimulating Factor; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Recombinant Proteins; Survival Rate | 1997 |
A pilot phase 2 study of surgical treatment after induction chemotherapy for resectable stage I to IIIA small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Lymph Node Excision; Male; Middle Aged; Pilot Projects | 1997 |
Five-day oral etoposide treatment for advanced small-cell lung cancer: randomized comparison with intravenous chemotherapy.
Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Palliative Care; Quality of Life; Survival Analysis; Treatment Outcome; Vincristine | 1997 |
Phase II study of ifosfamide and etoposide chemotherapy for extensive-disease small-cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Female; Humans; Ifosfamide; Leukopenia; Lung Neoplasms; Male; Middle Aged; Neutropenia; Sepsis; Survival Analysis | 1997 |
Dose-intensity of a four-drug chemotherapy regimen with or without recombinant human granulocyte-macrophage colony-stimulating factor in extensive-stage small-cell lung cancer: a multicenter randomized phase III study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Drug Administration Schedule; Epirubicin; Etoposide; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Middle Aged; Recombinant Proteins; Survival Analysis | 1997 |
Gemcitabine and etoposide in small cell lung cancer: phase I and II trials.
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Deoxycytidine; Etoposide; Female; Gemcitabine; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Ribonucleotide Reductases | 1997 |
[A study on treatment of lung cancer by combined therapy of traditional Chinese medicine and chemotherapy].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Diagnosis, Differential; Drugs, Chinese Herbal; Etoposide; Female; Humans; Lung Neoplasms; Male; Medicine, Chinese Traditional; Middle Aged; Mitomycin; Survival Rate; Vindesine | 1996 |
Phase I study of paclitaxel and oral etoposide in previously untreated non-small-cell and extensive small-cell lung cancer.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Paclitaxel | 1997 |
Prognostic factors and prognostic staging system for small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; L-Lactate Dehydrogenase; Lung Neoplasms; Male; Middle Aged; Multivariate Analysis; Neoplasm Staging; Prognosis; Radiotherapy Dosage; Regression Analysis; Survival Rate; Vincristine | 1997 |
Randomized trial of alternating versus sequential radiotherapy/chemotherapy in limited-disease patients with small-cell lung cancer: a European Organization for Research and Treatment of Cancer Lung Cancer Cooperative Group Study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Survival Rate | 1997 |
Dose-intensive chemotherapy in extensive-stage small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Incidence; Lung Neoplasms; Male; Middle Aged; Neutropenia; Treatment Outcome; Vincristine | 1997 |
Randomized study of initial versus late chest irradiation combined with chemotherapy in limited-stage small-cell lung cancer. Aarhus Lung Cancer Group.
Topics: Actuarial Analysis; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Leukocyte Count; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Platelet Count; Radiography; Radiotherapy Dosage; Radiotherapy, Adjuvant; Survival Analysis; Time Factors; Treatment Outcome; Vincristine | 1997 |
Outpatient treatment with epirubicin and oral etoposide in patients with small-cell lung cancer.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Epirubicin; Etoposide; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Outpatients; Survival Rate | 1997 |
Ifosfamide/carboplatin/etoposide/paclitaxel in advanced lung cancer: update and preliminary survival analysis.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Paclitaxel; Survival Analysis | 1997 |
A phase II study evaluating the efficacy of carboplatin, etoposide, and paclitaxel with granulocyte colony-stimulating factor in patients with stage IIIB and IV non-small cell lung cancer and extensive small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Etoposide; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Neoplasm Staging; Paclitaxel; Pilot Projects | 1997 |
A randomized study of etoposide and carboplatin with or without paclitaxel in the treatment of small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Cranial Irradiation; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Paclitaxel; Radiotherapy Dosage | 1997 |
A phase I study of cisplatin, etoposide, and paclitaxel in small cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Survival Analysis | 1997 |
Paclitaxel, carboplatin, and oral etoposide: a phase II trial in limited-stage small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Paclitaxel | 1997 |
[Chemotherapy versus chemoradiotherapy in patients with limited small cell lung carcinoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Survival Rate; Vincristine | 1997 |
Randomized trial of chemotherapy and radiation therapy with or without warfarin for limited-stage small-cell lung cancer: a Cancer and Leukemia Group B study.
Topics: Adult; Aged; Amsacrine; Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Disease-Free Survival; Etoposide; Female; Hemorrhage; Humans; Lung Neoplasms; Male; Middle Aged; Recurrence; Survival Analysis; Warfarin | 1997 |
A randomized study of chemotherapy with cisplatin plus etoposide versus chemoendocrine therapy with cisplatin, etoposide and the pineal hormone melatonin as a first-line treatment of advanced non-small cell lung cancer patients in a poor clinical state.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Lung Neoplasms; Male; Melatonin; Middle Aged; Prognosis; Remission Induction | 1997 |
Paclitaxel, carboplatin, and extended-schedule etoposide in the treatment of small-cell lung cancer: comparison of sequential phase II trials using different dose-intensities.
Topics: Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Female; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Survival Analysis; Thrombocytopenia | 1997 |
A randomized, controlled phase III study of cyclophosphamide, doxorubicin, and vincristine with etoposide (CAV-E) or teniposide (CAV-T), followed by recombinant interferon-alpha maintenance therapy or observation, in small cell lung carcinoma patients wit
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Interferon alpha-2; Interferon-alpha; Lung Neoplasms; Male; Middle Aged; Recombinant Proteins; Survival Analysis; Teniposide; Treatment Outcome; Vincristine | 1997 |
Re: five-day oral etoposide treatment for advanced small-cell lung cancer: randomized comparison with intravenous chemotherapy.
Topics: Administration, Oral; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Humans; Infusions, Intravenous; Lung Neoplasms; Middle Aged; Palliative Care; Survival Analysis; Treatment Outcome | 1997 |
The impact of Filgrastim schedule variation on hematopoietic recovery post-chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Hematopoiesis; Humans; Infusions, Intravenous; Injections, Subcutaneous; Lung Neoplasms; Male; Middle Aged; Neutropenia; Recombinant Proteins; Time Factors | 1997 |
Cisplatin, ifosfamide, and prolonged oral etoposide in the treatment of patients with extensive small cell lung carcinoma.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Disease-Free Survival; Etoposide; Female; Granulocytes; Humans; Ifosfamide; Leukocyte Count; Lung Neoplasms; Male; Middle Aged; Nausea; Neoplasm Staging; Neutropenia; Remission Induction; Survival Rate; Thrombocytopenia; Vomiting | 1998 |
Integration of filgrastim into chemoradiation for limited small cell lung cancer: a Phase I study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cohort Studies; Combined Modality Therapy; Disease-Free Survival; Etoposide; Female; Fever; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Neutropenia; Recombinant Proteins; Thrombocytopenia | 1998 |
Intervention with the hypoxic tumor cell sensitizer etanidazole in the combined modality treatment of limited stage small-cell lung cancer. A one-institution study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etanidazole; Etoposide; Humans; Lung Neoplasms; Peripheral Nervous System Diseases; Radiation-Sensitizing Agents; Vincristine | 1998 |
Effects of granulocyte-macrophage colony-stimulating factor and dose intensification of V-ICE chemotherapy in small-cell lung cancer: a prospective randomized study of 300 patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Double-Blind Method; Etoposide; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Prospective Studies; Survival Rate; Vincristine | 1998 |
Preliminary study of efficacy of intravenous cisplatin plus oral etoposide in small cell lung cancer.
Topics: Administration, Oral; Aged; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Etoposide; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Treatment Outcome | 1998 |
Results of a phase III, double-blind, placebo-controlled trial of megestrol acetate modulation of P-glycoprotein-mediated drug resistance in the first-line management of small-cell lung carcinoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Disease Progression; Disease-Free Survival; Double-Blind Method; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Lung Neoplasms; Male; Megestrol Acetate; Middle Aged; Neoplasm Proteins; Vincristine | 1998 |
Carboplatin, etoposide, and accelerated hyperfractionated radiotherapy for elderly patients with limited small cell lung carcinoma: a phase II study.
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Etoposide; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Radiotherapy Dosage; Survival Analysis | 1998 |
A phase II study of carboplatin and prolonged administration of oral etoposide in patients with small-cell lung cancer.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neutropenia; Survival Rate; Thrombocytopenia | 1997 |
Paclitaxel, carboplatin, and extended-schedule oral etoposide for small-cell lung cancer.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Treatment Outcome | 1998 |
Phase I study of paclitaxel and etoposide for metastatic or recurrent malignancies.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Female; Filgrastim; Germinoma; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Recombinant Proteins | 1998 |
Concurrent cisplatin, prolonged oral etoposide, and vincristine plus chest and brain irradiation for limited small cell lung cancer: a phase II study of the Southwest Oncology Group (SWOG-9229).
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Survival Analysis; Vincristine | 1998 |
Phase II trial of combination chemotherapy with cisplatin, carboplatin and etoposide in stage IIIB and IV small-cell lung cancer. Fukuoka Lung Cancer Study Group.
Topics: Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Hematologic Diseases; Humans; Lung Neoplasms; Male; Middle Aged; Nausea; Neoplasm Staging; Survival Rate; Treatment Outcome; Vomiting | 1998 |
Phase II trial of recombinant IFN-alpha2a with etoposide/cisplatin induction and interferon/megestrol acetate maintenance in extensive small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Interferon alpha-2; Interferon-alpha; Lung Neoplasms; Male; Megestrol Acetate; Middle Aged; Recombinant Proteins | 1998 |
High pre-treatment serum level of vascular endothelial growth factor (VEGF) is associated with poor outcome in small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Endothelial Growth Factors; Etoposide; Female; Humans; Interferon alpha-2; Interferon-alpha; Lung Neoplasms; Lymphokines; Male; Middle Aged; Prognosis; Recombinant Proteins; Survival Analysis; Time Factors; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1998 |
New combination of the old drugs for elderly patients with small-cell lung cancer: a phase II study of the PAVE regimen.
Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Prognosis; Survival Rate; Vincristine | 1998 |
Psychologic and neuropsychologic functioning of patients with limited small-cell lung cancer treated with chemotherapy and radiation therapy with or without warfarin: a study by the Cancer and Leukemia Group B.
Topics: Adult; Aged; Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cognition; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Doxorubicin; Emotions; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neuropsychological Tests; Trail Making Test; Warfarin | 1998 |
Optimal duration of chemotherapy in small cell lung cancer: a randomized study of 4 versus 6 cycles of cisplatin-etoposide.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Dose-Response Relationship, Drug; Etoposide; Female; Hematologic Diseases; Humans; Kidney Diseases; Lung Neoplasms; Male; Middle Aged; Nausea; Remission Induction; Survival Analysis | 1998 |
Phase III study of intensive weekly chemotherapy with recombinant human granulocyte colony-stimulating factor versus standard chemotherapy in extensive-disease small-cell lung cancer. The Japan Clinical Oncology Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Middle Aged; Neutropenia; Recombinant Proteins; Recurrence; Survival Rate; Treatment Outcome; Vincristine | 1998 |
Does chemotherapy-induced leukopenia predict a response in small-cell lung cancer?
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Epirubicin; Etoposide; Female; Humans; Leukocyte Count; Leukopenia; Male; Middle Aged; Predictive Value of Tests; Prognosis; Prospective Studies; Regression Analysis; Treatment Outcome; Vincristine | 1998 |
Phase II trial of carboplatin plus oral etoposide for elderly patients with small-cell lung cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Female; Humans; Lung Neoplasms; Male | 1998 |
A randomized trial of hybrid administration of cyclophosphamide, doxorubicin, and vincristine (CAV)/cisplatin and etoposide (PVP) versus sequential administration of CAV-PVP for the treatment of patients with small cell lung carcinoma: results of long ter
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Survival Analysis; Treatment Outcome; Vincristine | 1998 |
Prognostic factors in surgically treated small cell cervical carcinoma followed by adjuvant chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Etoposide; Female; Humans; Middle Aged; Neoplasm Staging; Prognosis; Prospective Studies; Uterine Cervical Neoplasms; Vinblastine; Vincristine | 1998 |
A phase II study of all-trans-retinoic acid plus cisplatin and etoposide in patients with extensive stage small cell lung carcinoma: an Eastern Cooperative Oncology Group Study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Survival Analysis; Tretinoin | 1998 |
Radiotherapy with/without cisplatin following chemotherapy in limited small-cell lung cancer.
Topics: Antineoplastic Agents; Carboplatin; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lung Neoplasms | 1998 |
Pharmacology of 21-day oral etoposide given in combination with i.v. cisplatin in patients with extensive-stage small cell lung cancer: a cancer and leukemia group B study (CALGB 9062).
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carcinoma, Small Cell; Cisplatin; Disease-Free Survival; Etoposide; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Regression Analysis; Time Factors | 1997 |
Phase I study to determine the maximum-tolerated dose of radiation in standard daily and hyperfractionated-accelerated twice-daily radiation schedules with concurrent chemotherapy for limited-stage small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Dose Fractionation, Radiation; Esophagitis; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Radiotherapy Dosage; Survival Rate; Treatment Outcome | 1998 |
Modified ice study: a phase II study of an intensive, modified ICE regimen (ifosfamide, carboplatin and etoposide) in patients with better prognosis, small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Female; Follow-Up Studies; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Patient Compliance; Prognosis; Quality of Life | 1998 |
A randomised, concentration-controlled, comparison of standard (5-day) vs. prolonged (15-day) infusions of etoposide phosphate in small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Organophosphorus Compounds | 1998 |
Phase II study of hyperfractionated radiotherapy and concurrent weekly alternating chemotherapy in limited-stage small cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Drug Administration Schedule; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Radiation-Sensitizing Agents; Radiotherapy, Adjuvant; Survival Analysis; Treatment Outcome; Vincristine | 1998 |
Cisplatin plus oral etoposide in the treatment of patients with advanced small cell lung cancer. Japan Clinical Oncology Group.
Topics: Administration, Oral; Adult; Aged; Alopecia; Anemia; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Etoposide; Female; Humans; Infusions, Intravenous; Leukopenia; Lung Neoplasms; Male; Middle Aged; Nausea; Thrombocytopenia; Vomiting | 1998 |
Twice-daily compared with once-daily thoracic radiotherapy in limited small-cell lung cancer treated concurrently with cisplatin and etoposide.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Dose Fractionation, Radiation; Etoposide; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Radiotherapy; Radiotherapy Dosage; Survival Rate | 1999 |
Dipyridamole modulated Tc-99m sestamibi lung SPECT in small cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Small Cell; Cisplatin; Dipyridamole; Drug Resistance, Multiple; Etoposide; Female; Humans; Lung; Lung Neoplasms; Male; Middle Aged; Radiopharmaceuticals; Technetium Tc 99m Sestamibi; Tomography, Emission-Computed, Single-Photon | 1999 |
Weekly alternating non-cross-resistant chemotherapy for small cell lung cancer with a good prognosis: a study of the Hellenic Cooperative Oncology Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cranial Irradiation; Drug Administration Schedule; Epirubicin; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Prognosis; Survival Analysis | 1999 |
A phase I study of gemcitabine/cisplatin/etoposide in the treatment of small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Deoxycytidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Female; Gemcitabine; Humans; Lung Neoplasms; Male; Middle Aged | 1998 |
Combination chemotherapy with low doses of weekly Carboplatin and oral Etoposide in poor risk small cell lung cancer.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Disease Progression; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Prognosis; Risk Assessment; Survival Analysis | 1999 |
Double-blind randomized study on the myeloprotective effect of melatonin in combination with carboplatin and etoposide in advanced lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cross-Over Studies; Cytoprotection; Double-Blind Method; Etoposide; Female; Hematologic Tests; Humans; Leukopoiesis; Lung Neoplasms; Male; Melatonin; Middle Aged; Protective Agents; Treatment Outcome | 1999 |
Standard- and high-dose etoposide, ifosfamide, carboplatin, and epirubicin in 100 patients with small-cell lung cancer: a mature follow-up report.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Disease-Free Survival; Epirubicin; Etoposide; Female; Follow-Up Studies; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Neoplasms, Second Primary | 1999 |
Standard combination versus alternating chemotherapy in small cell lung cancer: a randomised clinical trial including 394 patients. 'Petites Cellules' Group.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Resistance, Neoplasm; Etoposide; Female; Heparin; Humans; Lomustine; Lung Neoplasms; Male; Middle Aged; Prospective Studies; Survival Rate | 1999 |
Modifying the ICE regimen for better prognosis small cell lung cancer--an update.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Ifosfamide; Lung Neoplasms; Pilot Projects; Prognosis; Survival Rate | 1999 |
A randomized clinical trial comparing concurrent and alternating thoracic irradiation for patients with limited small cell lung carcinoma. "Petites Cellules" Group.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neutropenia; Pulmonary Fibrosis; Radiotherapy; Radiotherapy Dosage; Survival Analysis; Survival Rate; Time Factors; Treatment Outcome; Vindesine | 1999 |
Phase II study of area under the plasma-concentration-versus-time curve-based carboplatin plus standard-dose intravenous etoposide in elderly patients with small-cell lung cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carboplatin; Carcinoma, Small Cell; Dose-Response Relationship, Drug; Etoposide; Female; Humans; Lung Neoplasms; Male; Multivariate Analysis; Survival Rate; Time Factors | 1999 |
Multiple courses of high-dose ifosfamide, carboplatin, and etoposide with peripheral-blood progenitor cells and filgrastim for small-cell lung cancer: A feasibility study by the European Group for Blood and Marrow Transplantation.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Dose-Response Relationship, Drug; Etoposide; Europe; Feasibility Studies; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Ifosfamide; Logistic Models; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Recombinant Proteins | 1999 |
Treatment of poor-prognosis extensive disease small-cell lung cancer with an all-oral regimen of etoposide and cyclophosphamide - a Southwest Oncology Group clinical and pharmacokinetic study.
Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Metabolic Clearance Rate; Middle Aged; Neoplasm Staging; Prognosis; Regression Analysis | 1999 |
Cisplatin, etoposide, and paclitaxel in the treatment of patients with extensive small-cell lung carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neutropenia; Paclitaxel | 1999 |
Randomized study of CODE versus alternating CAV/EP for extensive-stage small-cell lung cancer: an Intergroup Study of the National Cancer Institute of Canada Clinical Trials Group and the Southwest Oncology Group.
Topics: Antineoplastic Combined Chemotherapy Protocols; Canada; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Female; Humans; Logistic Models; Lung Neoplasms; Male; Middle Aged; Prognosis; Survival Analysis; United States; Vincristine | 1999 |
Phase III comparison of twice-daily split-course irradiation versus once-daily irradiation for patients with limited stage small-cell lung carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Disease Progression; Dose Fractionation, Radiation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Radiation Injuries; Sensitivity and Specificity; Survival Analysis | 1999 |
Moderate dose-escalation of combination chemotherapy with concomitant thoracic radiotherapy in limited-disease small-cell lung cancer: prolonged intrathoracic tumor control and high central nervous system relapse rate. Groupe d'Oncologie-Pneumologie Clini
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Epirubicin; Etoposide; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Nervous System Neoplasms; Neutropenia; Recurrence; Survival Rate; Thoracic Neoplasms; Thrombocytopenia; Treatment Outcome | 1999 |
A phase I study of paclitaxel, etoposide, and cisplatin in extensive stage small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Neutropenia; Paclitaxel; Survival Rate; Time Factors | 1999 |
The addition of cisplatin to cyclophosphamide-doxorubicin-etoposide combination chemotherapy in the treatment of patients with small cell lung carcinoma: A randomized study of 457 patients. "Petites Cellules" Group.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Middle Aged; Survival Analysis; Treatment Outcome | 1999 |
[Combined alternating radiochemotherapy in stage III (TNM) (limited disease) small cell bronchial carcinoma: a phase II study with carboplatin/etoposide/vincristine and alternating radiotherapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Combined Modality Therapy; Dose Fractionation, Radiation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Survival Analysis; Vincristine | 1999 |
Improving survival without reducing quality of life in small-cell lung cancer patients by increasing the dose-intensity of chemotherapy with granulocyte colony-stimulating factor support: results of a British Medical Research Council Multicenter Randomize
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Disease-Free Survival; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Middle Aged; Neutropenia; Quality of Life; Thrombocytopenia | 2000 |
A phase I dose escalation study of multicyclic, dose-intensive chemotherapy with peripheral blood stem cell support for small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Etoposide; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Ifosfamide; Infusions, Intravenous; Injections, Subcutaneous; Leukapheresis; Lung Neoplasms; Male; Middle Aged; Radiotherapy; Recombinant Proteins; Transplantation, Autologous; Treatment Outcome | 2000 |
Significance of neuron-specific enolase levels before and during therapy for small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Disease Progression; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Megestrol; Middle Aged; Neoplasm Staging; Phosphopyruvate Hydratase; Survival Rate; Time Factors | 2000 |
Multi-institutional phase I/II trial of paclitaxel, cisplatin, and etoposide with concurrent radiation for limited-stage small-cell lung carcinoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Etoposide; Feasibility Studies; Female; Humans; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Survival Analysis | 2000 |
Concurrent cisplatin/etoposide chemotherapy plus twice daily thoracic radiotherapy in limited stage small cell lung cancer: a phase II study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Etoposide; Female; Humans; Injections, Intravenous; Lung Neoplasms; Male; Middle Aged; Prospective Studies; Survival Analysis; Treatment Outcome | 2000 |
Phase II trial of up-front accelerated thoracic radiotherapy combined with chemotherapy and optional up-front prophylactic cranial irradiation in limited small-cell lung cancer. Groupe d'Oncologie Thoracique des Régions Alpines.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Dose Fractionation, Radiation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Radiation Injuries; Radiotherapy Dosage; Survival Rate | 2000 |
A phase II study of combined chemoradiotherapy for limited disease-small-cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Doxorubicin; Esophagitis; Etoposide; Female; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Survival Analysis; Thrombocytopenia; Treatment Outcome | 2000 |
Interferon-alpha and 13-cis-retinoic acid as maintenance therapy after high-dose combination chemotherapy with growth factor support for small cell lung cancer--a feasibility study.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Drug Administration Schedule; Etoposide; Feasibility Studies; Female; Finland; Humans; Ifosfamide; Injections, Subcutaneous; Interferon-alpha; Isotretinoin; Lung Neoplasms; Male; Middle Aged | 2000 |
Reduction of oral mucositis by filgrastim (r-metHuG-CSF) in patients receiving chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Middle Aged; Mouth Mucosa; Necrosis; Neutropenia; Proportional Hazards Models; Prospective Studies; Recombinant Proteins; Stomatitis; Survival Analysis | 1999 |
Phase II study of ifosfamide, carboplatin, etoposide and GM-CSF in small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Dose-Response Relationship, Drug; Etoposide; Female; Follow-Up Studies; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Survival Rate | 2000 |
[Peripheral blood stem cell harvest in patients with limited stage small-cell lung cancer].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Blood Component Removal; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Lung Neoplasms; Male; Middle Aged | 2000 |
[Evaluation of nervous system disorders during the course of gastric carcinoma on the basis of clinical electrophysiologic analysis].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Electrophysiology; Epirubicin; Etoposide; Evoked Potentials, Auditory; Evoked Potentials, Auditory, Brain Stem; Evoked Potentials, Visual; Female; Fluorouracil; Humans; Male; Middle Aged; Nervous System Diseases; Paraneoplastic Syndromes; Stomach Neoplasms | 1999 |
Cisplatin, ifosfamide, oral etoposide, and concurrent accelerated hyperfractionated thoracic radiation for patients with limited small-cell lung carcinoma: results of radiation therapy oncology group trial 93-12.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Disease-Free Survival; Dose Fractionation, Radiation; Esophagitis; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Neutropenia; Treatment Outcome | 2000 |
[Pilot study of dose intensive weekly chemotherapy followed by cisplatin plus etoposide with concurrent thoracic irradiation for limited-disease small-cell lung cancer. West Japan Thoracic Oncology Group].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Pilot Projects; Survival Rate | 2000 |
[Combination of irinotecan hydrochloride and etoposide for treatment of refractory or relapsed small-cell lung cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Etoposide; Female; Humans; Irinotecan; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local | 2000 |
Lenograstim as support for ACE chemotherapy of small-cell lung cancer: a phase III, multicenter, randomized study.
Topics: Adjuvants, Immunologic; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Lenograstim; Leukocyte Count; Lung Neoplasms; Male; Middle Aged; Neutrophils; Recombinant Proteins; Remission Induction; Survival Rate | 2000 |
Sample sizes for cancer trials where Health Related Quality of Life is the primary outcome.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Etoposide; Humans; Lung Neoplasms; Methotrexate; Normal Distribution; Quality of Life; Randomized Controlled Trials as Topic; Sample Size; Statistics as Topic; Surveys and Questionnaires; Vincristine | 2000 |
Analysis of messy longitudinal data from a randomized clinical trial. MRC Lung Cancer Working Party.
Topics: Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cytarabine; Data Interpretation, Statistical; Etoposide; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Models, Statistical; Quality of Life; Randomized Controlled Trials as Topic; Time Factors | 2000 |
Population pharmacokinetics of doxorubicin, etoposide and ifosfamide in small cell lung cancer patients: results of a multicentre study.
Topics: Aged; Antineoplastic Agents; Carcinoma, Small Cell; Doxorubicin; Etoposide; Humans; Ifosfamide; Lung Neoplasms; Middle Aged | 2000 |
Feasibility and preliminary results of intensive chemotherapy and extensive irradiation in selected patients with limited small-cell lung carcinoma--results of three consecutive phase II programs.
Topics: Antineoplastic Agents; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Feasibility Studies; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Radiotherapy Dosage; Survival Analysis; Treatment Outcome; Vindesine | 2000 |
Effect of chemotherapy on pulmonary epithelial permeability in lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Gas Analysis; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Membrane Permeability; Cisplatin; Doxorubicin; Etoposide; Forced Expiratory Volume; Humans; Ifosfamide; Lung; Lung Neoplasms; Male; Metabolic Clearance Rate; Middle Aged; Mitomycin; Mucociliary Clearance; Respiratory Mucosa; Technetium Tc 99m Pentetate; Vital Capacity | 2000 |
A randomized trial of amifostine as a cytoprotective agent in patients receiving chemotherapy for small cell lung cancer.
Topics: Adult; Aged; Amifostine; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Neutropenia; Survival Analysis; Thrombocytopenia | 2001 |
Phase I study of a weekly infusion of irinotecan hydrochloride (CPT-11) and a 14-day continuous infusion of etoposide in patients with lung cancer: JCOG trial 9408.
Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Drug Administration Schedule; Etoposide; Female; Humans; Infusions, Intravenous; Irinotecan; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged | 2000 |
Use of hematopoietic progenitors in whole blood to support dose-dense chemotherapy: a randomized phase II trial in small-cell lung cancer patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Platelets; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Dose-Response Relationship, Drug; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Ifosfamide; Lung Neoplasms; Male; Mesna; Middle Aged; Platelet Count; Quality of Life | 2001 |
Etoposide plus cisplatin with or without the combination of 4'-epidoxorubicin plus cyclophosphamide in treatment of extensive small-cell lung cancer: a French Federation of Cancer Institutes multicenter phase III randomized study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; France; Humans; Lung Neoplasms; Male; Middle Aged; Proportional Hazards Models; Quality of Life; Risk; Surveys and Questionnaires; Survival Analysis; Treatment Outcome | 2001 |
A phase II study of VP-16-fosfamide-cisplatin combination chemotherapy plus early concurrent thoracic irradiation for previously untreated limited small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Survival Analysis; Thorax | 2000 |
Topotecan versus observation after cisplatin plus etoposide in extensive-stage small-cell lung cancer: E7593--a phase III trial of the Eastern Cooperative Oncology Group.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Quality of Life; Survival Analysis; Topotecan; Treatment Outcome | 2001 |
Paclitaxel added to the cisplatin/etoposide regimen in extensive-stage small cell lung cancer -- the use of complete response rate as the primary endpoint in phase II trials.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Endpoint Determination; Etoposide; Feasibility Studies; Humans; Lung Neoplasms; Multicenter Studies as Topic; Paclitaxel; Prognosis; Randomized Controlled Trials as Topic; Remission Induction; Survival Rate; Treatment Failure | 2001 |
A phase II study of weekly alternating chemotherapy in extensive-stage small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Drug Administration Schedule; Etoposide; Female; Humans; Ifosfamide; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Survival Analysis; Treatment Outcome; Vincristine | 2001 |
Combination chemotherapy for extensive small cell lung cancer -- experience from India.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Drug Administration Schedule; Drug Costs; Etoposide; Female; Follow-Up Studies; Humans; Ifosfamide; India; Lung Neoplasms; Male; Mesna; Middle Aged; Patient Compliance; Poverty; Survival Analysis; Survival Rate; Treatment Outcome; Vincristine | 2001 |
A multicenter randomized clinical trial comparing paclitaxel-cisplatin-etoposide versus cisplatin-etoposide as first-line treatment in patients with small-cell lung cancer.
Topics: Adult; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Fatigue; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nausea; Neutropenia; Paclitaxel; Survival Rate; Thrombocytopenia; Treatment Outcome; Vomiting | 2001 |
[The effect of small cell lung cancer extension on secretion of interleukin-2 (IL-2) and interferon gamma (IFM gamma) in whole blood culture stimulated with mitogens].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Epirubicin; Etoposide; Female; Glucuronates; Humans; Ifosfamide; Interferon-gamma; Interleukin-2; Lung Neoplasms; Male; Middle Aged; Radiotherapy, Adjuvant; Remission Induction | 2001 |
Multicenter phase II trial of paclitaxel, cisplatin, and etoposide with concurrent radiation for limited-stage small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Paclitaxel | 2001 |
Gemcitabine plus etoposide in chemonaive extensive disease small-cell lung cancer: a multi-centre phase II study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Deoxycytidine; Etoposide; Female; Gemcitabine; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Survival Analysis; Treatment Outcome | 2001 |
Cisplatin, etoposide, and paclitaxel with granulocyte colony-stimulating factor in untreated patients with extensive-stage small cell lung cancer: a phase II trial of the Southwest Oncology Group.
Topics: Adult; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Fatigue; Female; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Middle Aged; Nausea; Neutropenia; Paclitaxel; Survival Analysis; Thrombocytopenia; Treatment Outcome; Vomiting | 2001 |
Carboplatin calculated with Chatelut's formula plus etoposide for elderly patients with small-cell lung cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Female; Humans; Leukopenia; Lung Neoplasms; Male; Neutropenia; Severity of Illness Index; Thrombocytopenia; Treatment Outcome | 2001 |
Gemcitabine/carboplatin versus cisplatin/etoposide for patients with poor-prognosis small cell lung cancer: a phase III randomized trial with quality-of-life evaluation.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Deoxycytidine; Etoposide; Female; Gemcitabine; Humans; Lung Neoplasms; Male; Middle Aged; Quality of Life; Survival Analysis | 2001 |
Etoposide phosphate with carboplatin in the treatment of elderly patients with small-cell lung cancer: a phase II study.
Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Female; Humans; Lung Neoplasms; Male; Organophosphorus Compounds; Survival Analysis; Treatment Outcome | 2001 |
A phase I trial of a 5-day schedule of intravenous topotecan and etoposide in previously untreated patients with small-cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Survival Rate; Topotecan; Treatment Outcome | 2001 |
Randomized comparison of early versus late hyperfractionated thoracic irradiation concurrently with chemotherapy in limited disease small-cell lung cancer: a randomized phase II study of the Hellenic Cooperative Oncology Group (HeCOG).
Topics: Adult; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Disease Progression; Dose Fractionation, Radiation; Etoposide; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Neutropenia; Survival Analysis; Thrombocytopenia; Treatment Outcome | 2001 |
A three-arm phase III randomised trial assessing, in patients with extensive-disease small-cell lung cancer, accelerated chemotherapy with support of haematological growth factor or oral antibiotics.
Topics: Administration, Oral; Adult; Aged; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Endpoint Determination; Etoposide; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Prognosis; Survival Rate; Time Factors; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination; Vindesine | 2001 |
Carboplatin-etoposide combination in small cell lung cancer patients older than 70 years: a phase II trial.
Topics: Administration, Oral; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Female; Humans; Lung Neoplasms; Male; Neoplasm Staging; Neutropenia; Survival Rate; Treatment Outcome | 2002 |
Commentary on "carboplatin-etoposide association in small cell lung cancer patients older than 70 years: a phase II trial".
Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Humans; Lung Neoplasms; Neoplasm Staging; Survival Rate; Treatment Outcome | 2002 |
Reduction of chemotherapy-induced febrile leucopenia by prophylactic use of ciprofloxacin and roxithromycin in small-cell lung cancer patients: an EORTC double-blind placebo-controlled phase III study.
Topics: Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophylaxis; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Double-Blind Method; Doxorubicin; Etoposide; Female; Fever; Fluoroquinolones; Granulocyte Colony-Stimulating Factor; Hospitalization; Humans; Infections; Infusions, Intravenous; Lung Neoplasms; Macrolides; Male; Middle Aged; Neutropenia; Placebos; Survival Analysis; Treatment Outcome | 2001 |
Irinotecan plus cisplatin compared with etoposide plus cisplatin for extensive small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Disease-Free Survival; Etoposide; Female; Humans; Irinotecan; Lung Neoplasms; Male; Middle Aged; Survival Analysis | 2002 |
Long-term results of a phase I/II study of high-dose thoracic radiotherapy with concomitant cisplatin and etoposide in limited stage small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Disease-Free Survival; Dose Fractionation, Radiation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged | 2001 |
A phase I study of sequential intravenous topotecan and etoposide in lung cancer patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Inhibitors; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neutropenia; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Topotecan; Treatment Outcome | 2001 |
Etoposide, ifosfamide and cisplatin (VIP) plus concurrent radiation therapy for previously untreated limited small cell lung cancer (SCLC): a Hoosier Oncology Group (HOG) phase II study.
Topics: Adult; Aged; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Etoposide; Female; Humans; Ifosfamide; Male; Middle Aged; Prognosis; Survival Rate | 2002 |
Maintenance daily oral etoposide versus no further therapy following induction chemotherapy with etoposide plus ifosfamide plus cisplatin in extensive small-cell lung cancer: a Hoosier Oncology Group randomized study.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Disease Progression; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Survival Rate; Time Factors | 2002 |
Intensive chemotherapy with whole blood stem-cell support and concurrent chest radiotherapy in small cell lung cancer: a phase I/II trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Chi-Square Distribution; Combined Modality Therapy; Disease Progression; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Prospective Studies; Radiotherapy Dosage; Survival Analysis; Treatment Outcome | 2002 |
[Combination chemotherapy with carboplatin and etoposide for elderly patients aged 76 years or older with small cell lung cancer].
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Survival Rate | 2002 |
Thymosin fraction V and intensive combination chemotherapy. Prolonging the survival of patients with small-cell lung cancer.
Topics: Antineoplastic Agents; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Ifosfamide; Lomustine; Lung Neoplasms; Male; Methotrexate; Procarbazine; Thymosin; Thymus Hormones; Vincristine | 1979 |
Cyclic alternating combination chemotherapy for small cell bronchogenic carcinoma.
Topics: Antineoplastic Agents; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Etoposide; Humans; Ifosfamide; Lomustine; Lung Neoplasms; Methotrexate; Procarbazine; Remission, Spontaneous; Vincristine | 1979 |
Therapeutic trials with VP-16-213 and VM-26: active agents in small cell lung cancer, non-Hodgkin's lymphomas, and other malignancies.
Topics: Alopecia; Carcinoma, Small Cell; Clinical Trials as Topic; Drug Evaluation; Etoposide; Humans; Leukemia; Leukopenia; Lung Neoplasms; Lymphoma; Podophyllotoxin; Teniposide | 1979 |
A phase II trial of cisplatin and prolonged administration of oral etoposide in extensive-stage small cell lung cancer.
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Survival Analysis; Treatment Outcome | 1992 |
Etoposide, ifosfamide, and cisplatin in extensive small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Treatment Outcome | 1992 |
Randomized study of cyclophosphamide, doxorubicin, and vincristine versus etoposide and cisplatin versus alternation of these two regimens in extensive small-cell lung cancer: a phase III trial of the Southeastern Cancer Study Group.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Evaluation; Etoposide; Female; Humans; Logistic Models; Lung Neoplasms; Male; Middle Aged; Survival Analysis; Vincristine | 1992 |
Phase I trial of granulocyte-macrophage colony-stimulating factor with high-dose cisplatin and etoposide for treatment of small-cell lung cancer: a study of the National Cancer Institute of Canada Clinical Trials Group.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Evaluation; Etoposide; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Middle Aged | 1992 |
Intensive chemotherapy for extensive-stage small-cell lung cancer (SCLC)
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Etoposide; Follow-Up Studies; Humans; Lung Neoplasms; Vincristine | 1992 |
[A phase II trial of pirarubicin in untreated disseminated small cell lung cancer. A cooperative study of the French Pneumo-Cancerology Group].
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Invasiveness; Remission Induction; Survival Rate | 1992 |
Comparison of two carboplatin-containing regimens with standard chemotherapy for small cell lung cancer in a randomised phase II study. The EORTC Lung Cancer Cooperative group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Evaluation; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Random Allocation; Time Factors; Vincristine | 1992 |
Cisplatin, doxorubicin, cyclophosphamide, and etoposide combination chemotherapy for small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Pilot Projects | 1992 |
Combination chemotherapy with carboplatin, etoposide, and vincristine as first-line treatment in small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Survival Analysis; Treatment Outcome; Vincristine | 1992 |
Six vs twelve cycles for complete responders to chemotherapy in small cell lung cancer: definitive results of a randomized clinical trial. The "Petites Cellules" Group.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; France; Humans; Lomustine; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging | 1992 |
Calculation of received dose intensity for combinations of drugs using small-cell lung carcinoma treatment regimens as examples.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Methotrexate; Numerical Analysis, Computer-Assisted; Vincristine | 1992 |
Phase II feasibility study of high dose epirubicin plus etoposide and cisplatin (HDEEC) regimen in small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Drug Evaluation; Epirubicin; Etoposide; Feasibility Studies; Humans; Lung Neoplasms; Male; Middle Aged; Treatment Outcome | 1992 |
Carboplatin/etoposide/vincristine therapy in small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Drug Evaluation; Epirubicin; Etoposide; Female; Follow-Up Studies; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Recurrence; Thrombocytopenia; Time Factors; Vincristine | 1992 |
Prolonged administration of oral etoposide plus cisplatin in extensive stage small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Leukocyte Count; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Platelet Count | 1992 |
Oral etoposide in oncology: an evolving role.
Topics: Administration, Oral; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Humans; Lung Neoplasms | 1992 |
Second-line carboplatin-based chemotherapy for small cell lung cancer: the Groningen experience.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Carcinoma, Small Cell; Clinical Trials, Phase II as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Mesna; Middle Aged; Pilot Projects; Remission Induction; Survival Rate; Vincristine | 1992 |
Phase II and III studies with carboplatin in small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carboplatin; Carcinoma, Small Cell; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Etoposide; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Remission Induction; Survival Rate; Vincristine | 1992 |
Treatment of small cell carcinoma of the cervix with cisplatin, doxorubicin, and etoposide.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Female; Humans; Hysterectomy; Infusions, Intravenous; Middle Aged; Neoplasm Staging; Prospective Studies; Uterine Cervical Neoplasms | 1992 |
A phase III comparison of etoposide/cisplatin with or without added ifosfamide in small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Survival Rate | 1992 |
Carboplatin and etoposide (CarE) combined with radiotherapy and vincristine, doxorubicin and cyclophosphamide (VAC) in limited small cell lung cancer. A phase II study.
Topics: Adolescent; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Etoposide; Female; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Radiography; Time Factors; Treatment Outcome; Vincristine | 1992 |
A phase II study of ifosfamide in combination with etoposide and cisplatin in the treatment of extensive small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Survival Analysis | 1992 |
Combination chemotherapy with oral etoposide.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Survival Analysis; Treatment Outcome | 1992 |
The activity of 10-, 14-, and 21-day schedules of single-agent etoposide in previously untreated patients with extensive small cell lung cancer.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Treatment Outcome | 1992 |
Cyclophosphamide, epirubicin, etoposide, cis platinum (CEVP) in combination with radiotherapy: evaluation of a protocol adopted for 6 years in 148 cases of small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Epirubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Survival Analysis | 1992 |
Extensive small-cell lung cancer. A randomized comparison of two chemotherapy programs with early crossover in instances of failure. Association pour le Traitement des Tumeurs Intra-Thoraciques (ATTIT).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Vincristine | 1992 |
Etoposide versus methotrexate in small cell bronchial carcinoma. A randomized study of two types of four-drug chemotherapy regimens.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Prospective Studies; Vincristine | 1992 |
[Studies of the possibility of long-term survival of patients with small cell lung cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Prognosis; Remission Induction; Survival Rate | 1992 |
[Comparison of 2 cisplatin and etoposide dosages in relapsing small cell lung cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Dose-Response Relationship, Drug; Etoposide; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Survival Analysis; Thrombocytopenia | 1992 |
CODE chemotherapy with or without recombinant human granulocyte colony-stimulating factor in extensive-stage small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Etoposide; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Hemoglobins; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Recombinant Proteins; Time Factors; Treatment Outcome; Vincristine | 1992 |
Carboplatin in small cell lung cancer: the Royal Marsden Hospital experience.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Combined Modality Therapy; Cranial Irradiation; Etoposide; Humans; Ifosfamide; Lung Neoplasms; Mesothelioma; Middle Aged; Palliative Care; Pleural Neoplasms; Remission Induction; Survival Rate | 1992 |
[Cisplatin etoposide versus cisplatin/etoposide/ifosfamide combination chemotherapy in small-cell lung cancer: a multicenter randomized controlled study. Hokkaido Study Group of Treatment for Small-Cell Lung Cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Ifosfamide; Japan; Lung Neoplasms; Male; Middle Aged; Remission Induction; Survival Rate | 1991 |
Sequential chemotherapy in good-prognosis patients with small-cell lung cancer.
Topics: Adult; Aged; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Methotrexate; Middle Aged; Prognosis; Vincristine; Vindesine | 1991 |
Randomized trial of cyclophosphamide, doxorubicin, and vincristine versus cisplatin and etoposide versus alternation of these regimens in small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Vincristine | 1991 |
Cyclic-alternating versus response-oriented chemotherapy in small-cell lung cancer: a German multicenter randomized trial of 321 patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Quality of Life; Survival Rate; Vincristine | 1991 |
Comparison of cyclophosphamide, doxorubicin, and vincristine with an alternating regimen of methotrexate, etoposide, and cisplatin/cyclophosphamide, doxorubicin, and vincristine in the treatment of extensive-disease small-cell lung carcinoma: a Mid-Atlant
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Prognosis; Proportional Hazards Models; Survival Rate; Vincristine | 1991 |
Teniposide and etoposide in previously untreated small-cell lung cancer: a randomized study.
Topics: Aged; Aged, 80 and over; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Prospective Studies; Teniposide | 1991 |
A randomised trial of planned versus as required chemotherapy in small cell lung cancer: a Cancer Research Campaign trial.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Quality of Life; Vincristine | 1991 |
A Medical Research Council phase II trial of alternating chemotherapy and radiotherapy in small-cell lung cancer. The Medical Research Council Lung Cancer Working Party.
Topics: Activities of Daily Living; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Feasibility Studies; Female; Humans; Lung Neoplasms; Male; Middle Aged; Radiotherapy Dosage; Remission Induction | 1991 |
Effective new low toxicity chemotherapy with carboplatin, vinblastine and methotrexate for small cell lung cancer: a randomised trial against doxorubicin, cyclophosphamide and etoposide.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Prognosis; Vinblastine | 1991 |
Small-cell carcinoma of the head and neck. A novel treatment regimen.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Evaluation; Etoposide; Female; Humans; Laryngeal Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Pilot Projects; Radiotherapy Dosage; Remission Induction; Tongue Neoplasms; Vincristine | 1991 |
Determining carboplatin/etoposide dosage in extensive stage small-cell lung cancer (SCLC).
Topics: Aged; Carboplatin; Carcinoma, Small Cell; Dose-Response Relationship, Drug; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging | 1991 |
Establishment of tumor cell lines as an independent prognostic factor for survival time in patients with small-cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cell Division; Cisplatin; Combined Modality Therapy; Culture Techniques; Cyclophosphamide; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Prognosis; Proportional Hazards Models; Tumor Cells, Cultured; Vincristine | 1991 |
Treatment of small cell lung cancer: experience at Maharaj Nakhon Chiang Mai Hospital.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Thailand; Vincristine | 1991 |
A randomised study of intravenous bolus versus continuous infusion of ifosfamide and doxorubicin with oral etoposide for small-cell lung cancer.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Survival Analysis | 1991 |
Reduction by granulocyte colony-stimulating factor of fever and neutropenia induced by chemotherapy in patients with small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Double-Blind Method; Doxorubicin; Drug Administration Schedule; Etoposide; Fever; Granulocyte Colony-Stimulating Factor; Humans; Infection Control; Length of Stay; Lung Neoplasms; Neutropenia; Recombinant Proteins; Survival Rate | 1991 |
A randomized trial to compare intravenous and oral etoposide in combination with cisplatin for the treatment of small cell lung cancer.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Confidence Intervals; Drug Administration Schedule; Etoposide; Female; Humans; Injections, Intravenous; Lung Neoplasms; Male; Middle Aged; Remission Induction | 1991 |
Daily oral etoposide in the treatment of cancer.
Topics: Administration, Oral; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Humans; Lung Neoplasms; Neoplasms; Neoplasms, Germ Cell and Embryonal | 1991 |
Carboplatin in small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Survival Rate; Vincristine | 1991 |
Limited small cell lung cancer: prognostic significance of a complete response to the induction phase of chemotherapy followed by thoracic irradiation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Prognosis; Radiotherapy, High-Energy; Vincristine | 1991 |
Treatment of limited small-cell lung cancer with concurrent etoposide/cisplatin and radiotherapy followed by intensification with high-dose cyclophosphamide: a Southwest Oncology Group study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Pilot Projects; Prognosis | 1991 |
Dose-intensity meta-analysis of chemotherapy regimens in small-cell carcinoma of the lung.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Evaluation; Etoposide; Humans; Lung Neoplasms; Meta-Analysis as Topic; Podophyllotoxin; Vincristine | 1991 |
Combination chemotherapy of limited-stage small-cell lung cancer. A controlled trial on 221 patients comparing two alternating regimens.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Hematologic Diseases; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Staging; Prospective Studies; Recurrence; Remission Induction; Survival Rate; Vincristine | 1991 |
Prospective study of etoposide scheduling in combination chemotherapy for limited disease small cell lung carcinoma.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Injections, Intravenous; Lung Neoplasms; Male; Middle Aged; Prospective Studies; Vincristine | 1991 |
Adjuvant chemotherapy for T1-2NOMO small cell lung cancer: single-agent or combination chemotherapy?
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Epirubicin; Etoposide; Female; Heart Failure; Humans; Lung Neoplasms; Male; Middle Aged; Nausea; Vomiting | 1991 |
Does the substitution of cisplatin in a standard four drug regimen improve survival in small cell carcinoma of the lung? A comparison of two chemotherapy regimens.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Survival Rate; Vincristine | 1991 |
Phase I study with combination therapy of pirarubicin, etoposide, and vincristine in small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Doxorubicin; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Remission Induction; Survival Rate; Vincristine | 1990 |
Pirarubicin phase II study in untreated metastatic small-cell lung carcinoma. A cooperative study of the Groupe Français de Pneumo-Cancérologie (GFPC).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Remission Induction; Survival Rate | 1990 |
A randomized study comparing etoposide and vindesine with or without cisplatin as induction therapy for small cell lung cancer. EORTC Lung Cancer Working Party.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Survival Rate; Vindesine | 1990 |
Phase II trial of etoposide and cisplatin for refractory small cell lung cancer: a Cancer and Leukemia Group B Study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Multicenter Studies as Topic; Remission Induction; Survival Rate; Time Factors | 1990 |
Treatment of limited-stage small-cell lung cancer with cyclophosphamide, doxorubicin, and vincristine with or without etoposide: a randomized trial of the North Central Cancer Treatment Group.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Middle Aged; Neoplasm Staging; Radiotherapy Dosage; Radiotherapy, High-Energy; Randomized Controlled Trials as Topic; Time Factors; Vincristine | 1990 |
Treatment of limited small-cell lung cancer with etoposide and cisplatin alternating with vincristine, doxorubicin, and cyclophosphamide versus concurrent etoposide, vincristine, doxorubicin, and cyclophosphamide and chest radiotherapy: a Southwest Oncolo
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Resistance; Etoposide; Humans; Lung Neoplasms; Lymphatic Metastasis; Neoplasm Recurrence, Local; Radiotherapy Dosage; Randomized Controlled Trials as Topic; Remission Induction; Survival Analysis; Vincristine | 1990 |
The response of cerebral metastases in small cell lung cancer to systemic chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Cyclophosphamide; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Multicenter Studies as Topic; Prospective Studies; Randomized Controlled Trials as Topic; Vincristine | 1990 |
Comparison of etoposide and cisplatin with bis-chloro-ethylnitrosourea, thiotepa, vincristine, and cyclophosphamide for salvage treatment in small cell lung cancer. A Southwest Oncology Group Study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Carmustine; Cisplatin; Cyclophosphamide; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Randomized Controlled Trials as Topic; Thiotepa; Vincristine | 1990 |
A randomized comparison of standard chemotherapy versus alternating chemotherapy and maintenance versus no maintenance therapy for extensive-stage small-cell lung cancer: a phase III study of the Eastern Cooperative Oncology Group.
Topics: Aged; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Multicenter Studies as Topic; Prospective Studies; Random Allocation; Remission Induction; Survival Rate; Vincristine | 1990 |
The clinical effect of medroxyprogesterone (MPA) in elderly patients with lung cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Lung Neoplasms; Male; Medroxyprogesterone; Randomized Controlled Trials as Topic; Remission Induction; Survival Analysis | 1990 |
Concurrent chemotherapy/radiotherapy for limited small-cell lung carcinoma: a Southwest Oncology Group Study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Drug Evaluation; Etoposide; Female; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Multicenter Studies as Topic; Remission Induction; Survival Rate; United States; Vincristine | 1990 |
[Small cell lung carcinoma. Value of the evaluation of extension for the therapeutic strategy].
Topics: Adrenal Gland Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Topic; Combined Modality Therapy; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Multicenter Studies as Topic; Neoplasm Staging; Prognosis; Prospective Studies; Spinal Cord Neoplasms | 1990 |
[Progress and obstacles in chemotherapy and combined modality treatment of small cell lung cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Procarbazine; Survival Rate; Vincristine | 1990 |
[Cisplatin-Vepeside versus Endoxan-Vepeside in the treatment of small cell bronchial cancer. A randomized study].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Etoposide; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Randomized Controlled Trials as Topic | 1990 |
Induction chemo-radiotherapy and maintenance alternating chemotherapy for small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Procarbazine; Vincristine | 1990 |
Vincristine, doxorubicin and cyclophosphamide with and without etoposide in limited small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Vincristine | 1990 |
Phase II feasibility study of high dose epirubicin-based regimens for untreated patients with small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Drug Administration Schedule; Epirubicin; Etoposide; Feasibility Studies; Female; Humans; Lung Neoplasms; Male; Middle Aged; Remission Induction | 1990 |
Alternating radiotherapy and chemotherapy in 173 consecutive patients with limited small cell lung carcinoma. GROP and the French Cancer Center's Lung Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; France; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Survival Rate | 1990 |
Thoracic radiotherapy variables: influence on local control in small cell lung cancer limited disease.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Etoposide; Humans; Lung Neoplasms; Radiotherapy Dosage; Survival Rate | 1990 |
[Clinical results of carboplatin in the treatment of malignant tumors. Clinical Cooperative Group of Carboplatin].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Ovarian Neoplasms | 1990 |
Accelerated chemotherapy with or without GM-CSF for small cell lung cancer: a non-randomised pilot study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukocyte Count; Leukopenia; Lung Neoplasms; Middle Aged; Pilot Projects; Platelet Count; Recombinant Proteins; Time Factors; Vincristine | 1990 |
The prognostic value of response to the first cycle of chemotherapy in small cell lung cancer. Results of a multicenter German trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Small Cell; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Lomustine; Lung Neoplasms; Male; Methotrexate; Nimustine; Nitrosourea Compounds; Peplomycin; Prognosis; Random Allocation; Vincristine; Vindesine | 1987 |
[A comparative randomized phase II study of CDDP, CDDP-carboquone (CQ) and CDDP-etoposide as second-line chemotherapy in small cell lung cancer (SCLC)].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carbazilquinone; Carcinoma, Small Cell; Cisplatin; Drug Evaluation; Etoposide; Female; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Random Allocation; Remission Induction | 1989 |
Etoposide combined with cyclophosphamide plus vincristine compared with doxorubicin plus cyclophosphamide plus vincristine and with high-dose cyclophosphamide plus vincristine in the treatment of small-cell carcinoma of the lung: a randomized trial of the
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; England; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Multicenter Studies as Topic; Random Allocation; Vincristine | 1989 |
Experience of a German multicenter study group with ifosfamide in small cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Germany, West; Humans; Ifosfamide; Lung Neoplasms; Male; Multicenter Studies as Topic; Neoplasm Staging; Random Allocation; Remission Induction; Vincristine | 1989 |
Etoposide compared with the combination of vincristine, doxorubicin, and cyclophosphamide in the treatment of small cell lung cancer.
Topics: Actuarial Analysis; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Vincristine | 1989 |
Duration of chemotherapy in small cell lung cancer: a Cancer Research Campaign trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Multicenter Studies as Topic; Random Allocation; Vincristine | 1989 |
Controlled trial of twelve versus six courses of chemotherapy in the treatment of small-cell lung cancer. Report to the Medical Research Council by its Lung Cancer Working Party.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Multicenter Studies as Topic; Prognosis; Quality of Life; Random Allocation; Vincristine | 1989 |
[Small cell lung cancer: a retrospective analysis of results of chemotherapy and combined modality treatment].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Nimustine; Procarbazine; Random Allocation; Remission Induction; Retrospective Studies; Vincristine | 1989 |
Primary chemotherapy of brain metastasis in small-cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Prospective Studies; Vincristine | 1989 |
Lack of relationship between in vitro tumor cell growth and prognosis in extensive-stage small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cell Division; Cisplatin; Clinical Trials as Topic; Etoposide; Female; Humans; Lung Neoplasms; Male; Prognosis; Prospective Studies; Random Allocation; Tumor Cells, Cultured | 1989 |
A randomized trial of anticoagulation with warfarin and of alternating chemotherapy in extensive small-cell lung cancer by the Cancer and Leukemia Group B.
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Prognosis; Random Allocation; Remission Induction; Warfarin | 1989 |
Alternating chemotherapy with or without VP-16 in extensive-stage small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lomustine; Lung Neoplasms; Methotrexate; Neoplasm Staging; Random Allocation; Remission Induction; Time Factors; Vincristine | 1989 |
Chemotherapy plus adjuvant surgery for local small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Leucovorin; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Staging; Pneumonectomy; Preoperative Care; Remission Induction; Vincristine | 1989 |
A randomized trial to evaluate the effect of schedule on the activity of etoposide in small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Half-Life; Humans; Lung Neoplasms; Metabolic Clearance Rate; Random Allocation; Vincristine | 1989 |
[Sequential induction chemotherapy and radiation treatment of inoperable small cell bronchial cancer. Results of a prospective randomized study].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Prospective Studies; Randomized Controlled Trials as Topic; Vincristine | 1989 |
Carboplatin in association with etoposide and either adriamycin or epirubicin for untreated small cell lung cancer: a dose escalation study of carboplatin. UCL Clinical Oncology Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carboplatin; Carcinoma, Small Cell; Doxorubicin; Epirubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Multicenter Studies as Topic; Neoplasm Staging; Organoplatinum Compounds | 1989 |
Treatment of small cell lung cancer with induction chemotherapy followed by late intensification.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Methotrexate; Middle Aged; Multicenter Studies as Topic; Neoplasm Staging; Remission Induction; Survival Rate; Vincristine | 1989 |
[Evaluation of the second line of treatment of patients with small cell carcinoma of the lung].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Remission Induction | 1989 |
Superiority of alternating non-cross-resistant chemotherapy in extensive small cell lung cancer. A multicenter, randomized clinical trial by the National Cancer Institute of Canada.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Resistance; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Prognosis; Prospective Studies; Random Allocation; Vincristine | 1987 |
A phase II trial of cyclophosphamide, etoposide, and cisplatin with combined chest and brain radiotherapy in limited small-cell lung cancer: a Cancer and Leukemia Group B Study.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Thorax | 1987 |
Cisplatin/etoposide versus ifosfamide/etoposide combination chemotherapy in small-cell lung cancer: a multicenter German randomized trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Resistance; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Random Allocation; Vincristine | 1987 |
The importance of dose and dose intensity in lung cancer chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Clinical Trials as Topic; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Vincristine | 1987 |
[Global approach to the treatment of small cell bronchial cancers].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Carcinoma, Small Cell; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Lomustine; Lung Neoplasms; Male; Middle Aged; Random Allocation | 1987 |
[Therapeutic results in the treatment of small cell bronchial cancer: experience of the EORTC Lung Cancer Working Party (Belgium)].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Humans; Lung Neoplasms; Pilot Projects; Vincristine | 1987 |
The effect of dose of thoracic irradiation on recurrence in patients with limited stage small cell lung cancer. Initial results of a Canadian Multicenter Randomized Trial.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Deglutition Disorders; Dose-Response Relationship, Radiation; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Radiation Dosage; Random Allocation; Vincristine | 1988 |
[Clinical trial of high-dose etoposide].
Topics: Adult; Aged; Carcinoma, Small Cell; Clinical Trials as Topic; Drug Evaluation; Etoposide; Female; Hodgkin Disease; Humans; Lung Neoplasms; Lymphoma, Non-Hodgkin; Male; Middle Aged | 1988 |
Cyclic alternating polychemotherapy with or without upper and lower half-body irradiation in small cell anaplastic lung cancer. A randomized study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Etoposide; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Random Allocation; Time Factors; Vincristine | 1987 |
Cisplatin plus etoposide consolidation following cyclophosphamide, doxorubicin, and vincristine in limited small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Resistance; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Vincristine | 1988 |
[Randomized comparative study of CE (CDDP plus etoposide) and CE-AVN (ACNU, VCR plus procarbazine) as combined anticancer chemotherapy in small cell cancer of the lung].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Etoposide; Humans; Lung Neoplasms; Nimustine; Nitrosourea Compounds; Procarbazine; Prognosis; Random Allocation; Vincristine | 1988 |
Cisplatin and etoposide as second-line chemotherapy in patients with small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Etoposide; Follow-Up Studies; Humans; Lung Neoplasms | 1988 |
A preliminary report: concurrent twice-daily radiotherapy plus platinum-etoposide chemotherapy for limited small cell lung cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Radiotherapy Dosage | 1988 |
Cost-effectiveness of cancer chemotherapy: an economic evaluation of a randomized trial in small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Canada; Carcinoma, Small Cell; Cisplatin; Cost-Benefit Analysis; Cyclophosphamide; Doxorubicin; Etoposide; Hospitalization; Humans; Lung Neoplasms; Outpatient Clinics, Hospital; Prognosis; Random Allocation; Retrospective Studies; Vincristine | 1988 |
[Phase III therapy study in patients with small cell bronchial cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Prospective Studies; Random Allocation; Vindesine | 1988 |
Complications of treatment of small cell carcinoma of the lung. Experience from a recent Canadian trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Vincristine | 1988 |
Co-trimoxazole prophylaxis during high-dose chemotherapy of small-cell lung cancer.
Topics: Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cats; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Combinations; Etoposide; Female; Humans; Infection Control; Lung Neoplasms; Male; Middle Aged; Nausea; Neutropenia; Random Allocation; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Vincristine; Vomiting | 1985 |
Randomized trial of three combinations of cisplatin with vindesine and/or VP-16-213 in the treatment of advanced non-small-cell lung cancer.
Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Drug Administration Schedule; Etoposide; Humans; Lung Neoplasms; Male; Middle Aged; Prognosis; Random Allocation; Vinblastine; Vindesine | 1985 |
Etoposide (VP-16-213). Current status of an active anticancer drug.
Topics: Animals; Carcinoma, Small Cell; Clinical Trials as Topic; DNA; Drug Administration Schedule; Drug Evaluation; Drug Evaluation, Preclinical; Drug Resistance; Etoposide; Female; Hodgkin Disease; Humans; Leukemia; Lung Neoplasms; Lymphoma; Male; Mice; Podophyllotoxin; Testicular Neoplasms; Tissue Distribution | 1985 |
Combination chemotherapy with adriamycin, etoposide, and cyclophosphamide for small cell carcinoma of the lung. A study by the EORTC Lung Cancer Working Party (Belgium).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Belgium; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Female; Follow-Up Studies; Hematologic Diseases; Humans; Lung Neoplasms; Male; Middle Aged | 1985 |
Randomized dose-response evaluation of etoposide in small cell carcinoma of the lung: a Southeastern Cancer Study Group Trial.
Topics: Carcinoma, Small Cell; Clinical Trials as Topic; Dose-Response Relationship, Drug; Etoposide; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Podophyllotoxin; Random Allocation | 1986 |
Combination chemotherapy with c-DDP, cyclophosphamide, etoposide and prednisolone in small cell carcinoma of the lung.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Prednisolone | 1985 |
The use of VP-16 plus cisplatin during induction chemotherapy for small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Prospective Studies; Random Allocation; Remission Induction; Vincristine | 1986 |
Clinical trials of cyclophosphamide, etoposide, and vincristine in the treatment of small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Random Allocation; Vincristine | 1986 |
Cyclophosphamide, doxorubicin, and etoposide as first-line therapy in the treatment of small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Prognosis; Random Allocation; Remission Induction; Vincristine | 1986 |
Initial therapy with cisplatin plus VP-16 in small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Prospective Studies; Random Allocation; Remission Induction; Vincristine | 1986 |
Doxorubicin, cyclophosphamide, etoposide and platinum, doxorubicin, cyclophosphamide and etoposide for small-cell carcinoma of the lung.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Prognosis; Remission Induction | 1986 |
Oral etoposide in small-cell lung cancer.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Topic; Etoposide; Humans; Lung Neoplasms | 1986 |
Combined alkylators and multiple-site irradiation for extensive small cell lung cancer: a Southwest Oncology Group Study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Drug Administration Schedule; Etoposide; Hematologic Diseases; Humans; Liver Neoplasms; Lung Neoplasms; Random Allocation | 1986 |
Addition of etoposide to cyclophosphamide, doxorubicin, and vincristine for remission induction and survival in patients with small cell lung cancer.
Topics: Actuarial Analysis; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Random Allocation; Vincristine | 1987 |
Carboplatin (Paraplatin; JM8) and etoposide (VP-16) as first-line combination therapy for small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Clinical Trials as Topic; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Time Factors | 1987 |
Alternating versus sequential chemotherapy in small cell lung cancer. A randomized German multicenter trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Ifosfamide; Lomustine; Lung Neoplasms; Male; Methotrexate; Prognosis; Vincristine; Vindesine | 1987 |
The superiority of combination chemotherapy including etoposide based on in vivo cell cycle analysis in the treatment of extensive small-cell lung cancer: a randomized trial of 288 consecutive patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Autopsy; Carcinoma, Small Cell; Clinical Trials as Topic; Drug Administration Schedule; Etoposide; Female; Hematologic Diseases; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Random Allocation | 1987 |
Multimodal therapy for limited small-cell lung cancer: a randomized study of induction combination chemotherapy with or without thoracic radiation in complete responders; and with wide-field versus reduced-field radiation in partial responders: a Southwes
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Etoposide; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Radiotherapy; Random Allocation; Vincristine | 1987 |
No routine role for vincristine, adriamycin, and cyclophosphamide (VAC) or thoracic radiation therapy in extensive stage small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Etoposide; Humans; Lomustine; Lung Neoplasms; Random Allocation; Remission Induction; Vincristine | 1987 |
Extensive stage small cell carcinoma of the bronchus. A randomised study of etoposide given orally by one-day or five-day schedule together with intravenous adriamycin and cyclophosphamide.
Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Bronchial Neoplasms; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Injections, Intravenous; Male; Middle Aged | 1987 |
Phase II trial evaluating continuous infusion of etoposide, cisplatin, and hexamethylmelamine in extensive-disease small cell carcinoma of the lung.
Topics: Adult; Aged; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Remission Induction | 1987 |
Small cell lung cancer trials in the EORTC.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lung Neoplasms | 1987 |
Canadian multicenter randomized trial comparing sequential and alternating administration of two non-cross-resistant chemotherapy combinations in patients with limited small-cell carcinoma of the lung.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Resistance; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Random Allocation; Vincristine | 1987 |
674 other study(ies) available for etoposide and Carcinoma, Oat Cell
Article | Year |
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Synthesis and cytotoxicity of novel lignans.
Topics: Antineoplastic Agents; Carcinoma, Small Cell; Humans; Lignans; Lung Neoplasms; Tumor Cells, Cultured | 1995 |
Design of antineoplastic agents on the basis of the "2-phenylnaphthalene-type" structural pattern. 2. Synthesis and biological activity studies of benzo]b]naphtho[2,3-d]furan-6,11-dione derivatives.
Topics: Antineoplastic Agents; Carcinoma, Small Cell; Cisplatin; DNA Topoisomerases, Type II; Furans; Humans; Leukemia, Promyelocytic, Acute; Naphthoquinones; Structure-Activity Relationship; Tumor Cells, Cultured | 1993 |
Heterogeneity or transformation? A whack-a-mole case of EGFR-mutant lung adenocarcinoma and small cell carcinoma: A case report.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Carcinoma, Small Cell; Drug Resistance, Neoplasm; ErbB Receptors; Etoposide; Humans; Lung Neoplasms; Mutation; Platinum; Protein Kinase Inhibitors; Small Cell Lung Carcinoma | 2022 |
Sequential small cell transformation and T790M mutation in an epidermal growth factor-mutant lung adenocarcinoma: A rare occurrence with significant management implications.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Aged; Carboplatin; Carcinoma, Small Cell; Drug Resistance, Neoplasm; Epidermal Growth Factor; ErbB Receptors; Etoposide; Female; Gefitinib; Humans; Lung Neoplasms; Mutation; Protein Kinase Inhibitors | 2022 |
Long-term complete response in small cell bladder carcinoma treated with carboplatin, etoposide, and atezolizumab.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Humans; Lung Neoplasms; Male; Urinary Bladder; Urinary Bladder Neoplasms | 2022 |
Iris metastasis as resistance mechanism to atezolizumab, carboplatin, and etoposide but responds to additional irinotecan and anlotinib in a small cell lung cancer patient.
Topics: Antineoplastic Combined Chemotherapy Protocols; Blindness; Carboplatin; Carcinoma, Small Cell; Etoposide; Female; Humans; Irinotecan; Iris; Lung Neoplasms; Small Cell Lung Carcinoma | 2023 |
Localized Colonic Small-Cell Carcinoma with Pathological Complete Response after Neoadjuvant Cisplatin and Etoposide: A Case Report.
Topics: Aged; Carcinoma, Small Cell; Cisplatin; Colonic Neoplasms; Etoposide; Humans; Male; Neoadjuvant Therapy; Neoplasm Recurrence, Local | 2023 |
The Indenoisoquinoline LMP517: A Novel Antitumor Agent Targeting both TOP1 and TOP2.
Topics: Animals; Camptothecin; Carcinoma, Small Cell; Cell Line, Tumor; Chickens; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Etoposide; Female; Histones; Humans; Indans; Isoquinolines; Lung Neoplasms; Lymphoma; Mice; Mice, Nude; Molecular Targeted Therapy; Neoplasm Proteins; Poultry Diseases; Random Allocation; Recombinant Proteins; Substrate Specificity; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Xenograft Model Antitumor Assays | 2020 |
Dose-intensive regimen treatment for small-cell carcinoma of the ovary of hypercalcemic type (SCCOHT).
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chemoradiotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Cytoreduction Surgical Procedures; Disease-Free Survival; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Female; Humans; Hypercalcemia; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Ovarian Neoplasms; Ovary; Prospective Studies; Retrospective Studies; Stem Cell Transplantation; Transplantation, Autologous; Young Adult | 2020 |
[A Case of Small Cell Carcinoma of the Bladder].
Topics: Aged; Carcinoma, Small Cell; Cystectomy; Etoposide; Humans; Male; Urinary Bladder Neoplasms | 2020 |
A case report of advanced gastric small cell carcinoma with neoadjuvant chemotherapy followed by radical total gastrectomy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Etoposide; Gastrectomy; Humans; Male; Middle Aged; Neoadjuvant Therapy; Quality of Life; Stomach Neoplasms; Treatment Outcome | 2020 |
Primary gastric small cell carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cardia; CD56 Antigen; Cisplatin; Etoposide; Gastric Fundus; Gastroscopy; Humans; Immunohistochemistry; Keratin-7; Male; Middle Aged; Stomach Neoplasms; Synaptophysin | 2017 |
Report: Small cell neuroendocrine carcinoma (SCNEC) of the tongue: A case report.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Humans; Male; Neoplasm Metastasis; Positron Emission Tomography Computed Tomography; Tongue Neoplasms | 2017 |
[A Case of Long Survival in Aggressively Growing Small Cell Carcinoma of the Bladder Successfully Treated by Combined Chemotherapy of Methotrexate, Etoposide and Cisplatin].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Magnetic Resonance Imaging; Male; Methotrexate; Time Factors; Urinary Bladder Neoplasms | 2017 |
Cycles of cisplatin and etoposide affect treatment outcomes in patients with FIGO stage I-II small cell neuroendocrine carcinoma of the cervix.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Neuroendocrine; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Drug Administration Schedule; Etoposide; Female; Humans; Kaplan-Meier Estimate; Neoplasm Staging; Retrospective Studies; Uterine Cervical Neoplasms | 2017 |
Giant small-cell neuroendocrine carcinoma infiltrating the heart.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Neuroendocrine; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Male; Mediastinal Neoplasms; Middle Aged | 2018 |
Biallelic tumour suppressor loss and DNA repair defects in de novo small-cell prostate carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carboplatin; Carcinoma, Small Cell; Cisplatin; Databases, Factual; DNA Repair; Etoposide; Gene Expression Profiling; Genes, Tumor Suppressor; Genetic Predisposition to Disease; Genomic Instability; Humans; Male; Middle Aged; Neoplasms, Complex and Mixed; Phenotype; Prostatic Neoplasms; Retrospective Studies; Time Factors; Treatment Outcome | 2018 |
Treatment and outcome of 432 patients with extensive-stage small cell lung cancer in first, second and third line - Results from the prospective German TLK cohort study.
Topics: Aged; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cohort Studies; Etoposide; Female; Germany; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Platinum Compounds; Prospective Studies; Survival Analysis; Treatment Outcome | 2019 |
A Common Purpuric Rash With Uncommon Association in a Woman With Pedal Edema.
Topics: Aged; Antineoplastic Agents; Carcinoma, Small Cell; Cisplatin; Edema; Etoposide; Fatal Outcome; Female; Humans; Lung Neoplasms; Purpura; Vasculitis, Leukocytoclastic, Cutaneous | 2019 |
[Analysis of drug therapy of lung cancer in Hungary].
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Databases, Factual; Deoxycytidine; Docetaxel; Drug Administration Schedule; Erlotinib Hydrochloride; Etoposide; Gemcitabine; Glutamates; Guanine; Humans; Hungary; Inpatients; Insurance, Health; Lung Neoplasms; Paclitaxel; Pemetrexed; Prescription Drugs; Quinazolines; Retrospective Studies; Taxoids; Topotecan | 2013 |
Treatment of small cell lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines.
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Combined Modality Therapy; Etoposide; Evidence-Based Medicine; Humans; Irinotecan; Lung Neoplasms; Neoplasm Staging; Patient Selection; Platinum Compounds; Positron-Emission Tomography | 2013 |
Multimodality treatment for poorly differentiated neuroendocrine head and neck carcinomas--a single institution experience.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Neuroendocrine; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Etoposide; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Retrospective Studies; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome | 2013 |
Long-term survival of a patient with primary small cell neuroendocrine carcinoma of the maxillary sinus: a case report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Neuroendocrine; Carcinoma, Small Cell; Chemoradiotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Etoposide; Humans; Induction Chemotherapy; Male; Maxillary Sinus Neoplasms; Middle Aged | 2013 |
NSE can predict the sensitivity to definitive chemoradiotherapy of small cell carcinoma of esophagus.
Topics: Aged; Antigens, Neoplasm; Biomarkers, Tumor; Carcinoembryonic Antigen; Carcinoma, Small Cell; Chemoradiotherapy; Cisplatin; Endosonography; Esophageal Neoplasms; Etoposide; Female; Humans; Keratin-19; Lymphatic Metastasis; Male; Middle Aged; Phosphopyruvate Hydratase; Positron-Emission Tomography; Predictive Value of Tests; Tomography, X-Ray Computed; Treatment Outcome | 2014 |
Long-term survival of a patient with extensive small cell carcinoma of unknown primary etiology complicated by nephrotic syndrome.
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Cranial Irradiation; Edema; Etoposide; Glomerulonephritis, Membranous; Humans; Irinotecan; Lymphatic Metastasis; Neoplasms, Unknown Primary; Nephrotic Syndrome; Paraneoplastic Syndromes; Pleural Effusion, Malignant; Proteinuria; Radiotherapy, Adjuvant; Remission Induction; Tomography, X-Ray Computed | 2014 |
Treatment of Small Cell Carcinoma of the Bladder With Chemotherapy and Radiation after Transurethral Resection of a Bladder Tumor.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Carcinoma, Transitional Cell; Chemoradiotherapy, Adjuvant; Cisplatin; Cohort Studies; Cystoscopy; Disease-Free Survival; Etoposide; Female; Humans; Male; Middle Aged; Neoplasm Staging; Neoplasms, Complex and Mixed; Organ Sparing Treatments; Retrospective Studies; Urinary Bladder; Urinary Bladder Neoplasms; Vinblastine; Vinorelbine | 2016 |
Analysis of the impact of platinum-based combination chemotherapy in small cell cervical carcinoma: a multicenter retrospective study in Chinese patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asian People; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Follow-Up Studies; Humans; Middle Aged; Paclitaxel; Retrospective Studies; Taxoids; Uterine Cervical Neoplasms; Young Adult | 2014 |
[Small cell carcinoma of the ovary].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Hysterectomy; Lymph Node Excision; Ovarian Neoplasms; Ovariectomy; Pelvic Pain; Radiotherapy, Adjuvant | 2014 |
A population pharmacodynamic model for lactate dehydrogenase and neuron specific enolase to predict tumor progression in small cell lung cancer patients.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carboplatin; Carcinoma, Small Cell; Cisplatin; Disease Progression; Disease-Free Survival; Etoposide; Humans; L-Lactate Dehydrogenase; Lung Neoplasms; Models, Biological; Phosphopyruvate Hydratase; Population; Predictive Value of Tests | 2014 |
Peptide receptor chemoradionuclide therapy in small cell carcinoma: from bench to bedside.
Topics: Animals; Antineoplastic Agents; Carboplatin; Carcinoma, Small Cell; Cell Line, Tumor; Etoposide; Female; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Octreotide; Organometallic Compounds; Radiopharmaceuticals; Receptors, Somatostatin; Small Cell Lung Carcinoma; Translational Research, Biomedical | 2015 |
Multidisciplinary management of small cell carcinoma of the breast: a case report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Breast Neoplasms; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Epirubicin; Etoposide; Female; Humans; Lymphatic Metastasis; Magnetic Resonance Imaging; Mastectomy, Modified Radical; Middle Aged; Neoadjuvant Therapy; Radiotherapy, Adjuvant; Time Factors; Treatment Outcome; Ultrasonography, Mammary | 2014 |
[Severe hyponatremia during chemotherapy for small cell carcinoma].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Coma; Etoposide; Humans; Hyponatremia; Inappropriate ADH Syndrome; Lung Neoplasms; Male; Recurrence; Tomography, X-Ray Computed | 2015 |
Extrapulmonary small cell carcinoma in head and neck.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Chemoradiotherapy; Chemotherapy, Adjuvant; Cisplatin; Disease Progression; Drug Combinations; Etoposide; Female; Head and Neck Neoplasms; Humans; Irinotecan; Male; Middle Aged; Neoplasm Staging; Oxonic Acid; Radiotherapy, Adjuvant; Survival Rate; Tegafur | 2015 |
Sepsis caused by Listeria monocytogenes during chemotherapy for small cell carcinoma of the thymus.
Topics: Aged; Ampicillin; Anti-Bacterial Agents; Antineoplastic Agents; Carboplatin; Carcinoma, Small Cell; Cefepime; Cephalosporins; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Listeria monocytogenes; Listeriosis; Meropenem; Neoplasm Recurrence, Local; Sepsis; Thienamycins; Thymus Gland; Thymus Neoplasms; Treatment Outcome | 2015 |
Effects and toxicity of neoadjuvant chemotherapy preoperative followed by adjuvant chemoradiation in small cell neurdendocrine cervical carcinoma.
Topics: Adult; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Neuroendocrine; Carcinoma, Small Cell; Chemoradiotherapy, Adjuvant; Cisplatin; Doxorubicin; Etoposide; Female; Hepatic Insufficiency; Humans; Hysterectomy; Ifosfamide; Middle Aged; Neoadjuvant Therapy; Neutropenia; Paclitaxel; Renal Insufficiency; Thrombocytopenia; Treatment Outcome; Uterine Cervical Neoplasms; Vincristine | 2015 |
Efficacy and safety of ifosfamide in combination with carboplatin and etoposide in small cell lung cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Disease-Free Survival; Etoposide; Febrile Neutropenia; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Ifosfamide; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Peripheral Nervous System Diseases; Treatment Outcome | 2015 |
Extrapulmonary Small Cell Carcinoma - a Case Series of Oropharyngeal and Esophageal Primary Sites Treated with Chemo-Radiotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chemoradiotherapy; Chemotherapy, Adjuvant; Cisplatin; Esophageal Neoplasms; Etoposide; Female; Humans; Male; Middle Aged; Neoadjuvant Therapy; Oropharyngeal Neoplasms; Palliative Care | 2015 |
[Radical surgery after successful chemotherapy in a case of primary small cell carcinoma of the liver].
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Etoposide; Female; Humans; Liver Neoplasms; Middle Aged | 2015 |
[SMALL CELL CARCINOMA OF THE PROSTATE: A CASE REPORT OF RELATIVE LONG-TERM SURVIVAL].
Topics: Aged; Anthracyclines; Antineoplastic Agents; Carboplatin; Carcinoma, Small Cell; Etoposide; Fatal Outcome; Humans; Lymphatic Metastasis; Male; Multimodal Imaging; Positron-Emission Tomography; Prostatic Neoplasms; Time Factors; Tomography, X-Ray Computed | 2015 |
[Prognostic impact of different chemotherapy strategies on small cell esophageal carcinoma].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Chi-Square Distribution; Cisplatin; Esophageal Neoplasms; Etoposide; Humans; Multivariate Analysis; Prognosis; Proportional Hazards Models; Retrospective Studies; Survival Rate; Treatment Outcome | 2015 |
Small cell carcinoma of the pyriform sinus successfully treated with concurrent chemo-radiotherapy: A case report.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chemoradiotherapy; Cisplatin; Etoposide; Humans; Hypopharyngeal Neoplasms; Lung Neoplasms; Male; Neoplasms, Second Primary; Pyriform Sinus; Small Cell Lung Carcinoma | 2016 |
Long term disease free survival with multimodal therapy in small cell bladder cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cystectomy; Disease-Free Survival; Etoposide; Humans; Lymph Node Excision; Male; Middle Aged; Prostatectomy; Treatment Outcome; Urinary Bladder Neoplasms | 2016 |
[Etoposide and Carboplatin Effective for Treatment of Small Cell Carcinoma of Prostate : A Report of Two Cases].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Humans; Male; Prostatic Neoplasms; Tomography, X-Ray Computed | 2016 |
[A case of small cell carcinoma of the ureter].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Etoposide; Humans; Irinotecan; Male; Ureteral Neoplasms | 2008 |
Small cell carcinoma of unknown primary presenting with disease confined to the central nervous system.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Central Nervous System Neoplasms; Combined Modality Therapy; Disease-Free Survival; Etoposide; Female; Humans; Male; Middle Aged; Neoplasms, Unknown Primary; Radiography; Radiotherapy Dosage | 2009 |
[Case of cancer-associated retinopathy in which immediate treatment succeeded].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Etoposide; Fatal Outcome; Humans; Lung Neoplasms; Male; Methylprednisolone; Paraneoplastic Syndromes; Prednisolone; Pulse Therapy, Drug; Retinal Diseases; Treatment Outcome | 2008 |
Small cell neuroendocrine carcinoma of the cervix: Analysis of outcome, recurrence pattern and the impact of platinum-based combination chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Neuroendocrine; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Retrospective Studies; Treatment Outcome; Uterine Cervical Neoplasms | 2009 |
[Clinical analysis of 81 cases with primary small cell carcinoma of the esophagus].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Esophageal Neoplasms; Esophagectomy; Etoposide; Female; Follow-Up Studies; Humans; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Neoplastic Cells, Circulating; Proportional Hazards Models; Retrospective Studies; Survival Rate | 2008 |
AKT/mTOR pathway activation and BCL-2 family proteins modulate the sensitivity of human small cell lung cancer cells to RAD001.
Topics: Animals; Antineoplastic Agents; Carcinoma, Small Cell; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Drug Resistance, Neoplasm; Etoposide; Everolimus; Humans; Lung Neoplasms; Mice; Protein Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Sirolimus; Stem Cell Factor; TOR Serine-Threonine Kinases | 2009 |
Small cell carcinoma of the pancreas: role of EUS-FNA and subsequent effective chemotherapy using carboplatin and etoposide.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Biopsy, Fine-Needle; Carboplatin; Carcinoma, Small Cell; Endosonography; Etoposide; Female; Humans; Male; Middle Aged; Pancreatic Neoplasms; Tomography, X-Ray Computed; Ultrasonography, Interventional | 2009 |
Isolated pancreatic metastases from a bronchogenic small cell carcinoma.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Bronchial Neoplasms; Carboplatin; Carcinoma, Small Cell; Etoposide; Female; Humans; Middle Aged; Pancreatic Neoplasms; Radiography; Ultrasonography | 2009 |
Familial small cell carcinoma of the ovary.
Topics: Abdominal Pain; Adult; Age of Onset; Anticipation, Genetic; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Child; Cisplatin; Combined Modality Therapy; Diseases in Twins; Etoposide; Family Health; Female; Hormone Replacement Therapy; Humans; Hypercalcemia; Incidence; Menopause, Premature; Ovarian Neoplasms; Ovariectomy; Pedigree; Radiotherapy, Adjuvant; Remission Induction | 2009 |
[Gastric metastasis from small cell lung cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Fatal Outcome; Female; Humans; Lung Neoplasms; Middle Aged; Neoplasm Metastasis; Pneumonia; Stomach Neoplasms; Vincristine | 2009 |
[A case of primary small cell carcinoma of the esophagus responding remarkably to carboplatin (CBDCA) + etoposide (VP-16) combination therapy and radiation therapy].
Topics: Aged; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Esophageal Neoplasms; Etoposide; Humans; Male | 2009 |
Primary small cell carcinoma of the stomach successfully treated with cisplatin and etoposide.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Male; Stomach Neoplasms; Tomography, X-Ray Computed | 2009 |
Small cell carcinoma of the gall bladder: role of adjuvant chemotherapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cholecystectomy, Laparoscopic; Cisplatin; Combined Modality Therapy; Etoposide; Female; Gallbladder Neoplasms; Humans; Neoplasm Staging; Radiotherapy | 2010 |
Surgical management for small cell carcinoma of the esophagus.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Esophageal Neoplasms; Esophagectomy; Etoposide; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Retrospective Studies; Treatment Outcome | 2010 |
[Treatment and prognosis of extrapulmonary small cell carcinoma of 243 cases].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Esophageal Neoplasms; Etoposide; Female; Follow-Up Studies; Gastrointestinal Neoplasms; Head and Neck Neoplasms; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Radiotherapy, High-Energy; Survival Rate; Urogenital Neoplasms; Young Adult | 2010 |
Achievement of a continuous complete remission in a kidney transplant patient with advanced donor-derived small cell carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cadaver; Carboplatin; Carcinoma, Small Cell; Etoposide; Glomerulonephritis; Humans; Immunosuppressive Agents; Immunotherapy; Kidney Transplantation; Male; Middle Aged; Neoplasm Metastasis; Tissue Donors | 2010 |
Small cell carcinoma of vulva: curative multimodal treatment in face of resistance to initial standard chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Disease-Free Survival; Etoposide; Female; Humans; Hyperthermia, Induced; Magnetic Resonance Imaging; Radiography; Tomography, Emission-Computed; Vulvar Neoplasms | 2010 |
Phase II study of dose-intense chemotherapy with sequential topoisomerase-targeting regimens with irinotecan/oxaliplatin followed by etoposide/carboplatin in chemotherapy naive patients with extensive small cell lung cancer.
Topics: Aged; Aged, 80 and over; Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carboplatin; Carcinoma, Small Cell; Disease-Free Survival; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA-Binding Proteins; Endonucleases; Etoposide; Female; Gene Expression Regulation, Neoplastic; Humans; Irinotecan; Lung Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Survival Analysis | 2011 |
Involved-field radiotherapy with concurrent chemotherapy for limited-stage small-cell lung cancer: disease control, patterns of failure and survival.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Dose Fractionation, Radiation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Proportional Hazards Models; Radiotherapy Dosage; Retrospective Studies; Survival Rate; Treatment Outcome | 2010 |
Ovarian small cell carcinoma, hypercalcemic type exhibiting a response to high-dose chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Etoposide; Female; Genes, BRCA1; Humans; Hypercalcemia; Lymphatic Metastasis; Neoplasm Staging; Ovarian Neoplasms; Paraneoplastic Syndromes; Peripheral Blood Stem Cell Transplantation | 2010 |
Complete remission in a patient with metastatic mixed adenocarcinoma/extrapulmonary small cell carcinoma of the prostate.
Topics: Adenocarcinoma; Androgen Antagonists; Bone Neoplasms; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Etoposide; Humans; Lung Neoplasms; Male; Middle Aged; Prostatic Neoplasms; Remission Induction | 2011 |
Presentation of a patient with pT2bN1M0 small cell carcinoma of the uterine cervix who obtained long-term survival with maintenance chemotherapy, and literature-based discussion.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Neoplasm Staging; Uterine Cervical Neoplasms | 2011 |
[Pneumocystis and Staphylococcus aureus pulmonary co-infection after chemotherapy for lung cancer].
Topics: Aged; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Ceftriaxone; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Etoposide; Fatal Outcome; Female; Humans; Immunocompromised Host; Lung Neoplasms; Opportunistic Infections; Pneumonia, Pneumocystis; Pneumonia, Staphylococcal; Staphylococcus aureus; Trimethoprim, Sulfamethoxazole Drug Combination | 2011 |
Impact of ERCC1 expression on treatment outcome in small-cell lung cancer patients treated with platinum-based chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chemoradiotherapy; Cisplatin; Disease-Free Survival; DNA Repair; DNA-Binding Proteins; DNA, Neoplasm; Endonucleases; Epirubicin; Etoposide; Female; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Neoplasm Proteins; Pilot Projects; Prognosis; Retrospective Studies; Single-Blind Method; Slovenia; Topotecan; Treatment Outcome; Vincristine | 2012 |
Small cell carcinoma of gastro-oesophageal junction with remarkable response to chemo-radiotherapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Chemoradiotherapy, Adjuvant; Cisplatin; Esophageal Neoplasms; Esophagogastric Junction; Etoposide; Humans; Male; Neoplasm Recurrence, Local; Positron-Emission Tomography; Remission Induction; Stomach Neoplasms; Tomography, X-Ray Computed; Treatment Outcome | 2012 |
The 2002 AJCC TNM classification is a better predictor of primary small cell esophageal carcinoma outcome than the VALSG staging system.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Esophageal Neoplasms; Esophagectomy; Etoposide; Female; Humans; Lymph Node Excision; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Paclitaxel; Radiotherapy, High-Energy; Retrospective Studies; Societies, Medical; Survival Rate; United States | 2013 |
Treatment update in small-cell lung cancer: from limited to extensive disease.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Etoposide; Humans; Lung Neoplasms; Neoplasm Metastasis; Neoplasm Staging; Paclitaxel; Small Cell Lung Carcinoma; Topotecan | 2012 |
Protein kinase C-epsilon promotes survival of lung cancer cells by suppressing apoptosis through dysregulation of the mitochondrial caspase pathway.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Small Cell; Caspases; Cell Survival; DNA, Antisense; DNA, Complementary; Drug Resistance, Neoplasm; Enzyme Activation; Etoposide; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Lung Neoplasms; Mitochondria; Phenotype; Protein Kinase C; Protein Kinase C-epsilon; Transcription, Genetic; Tumor Cells, Cultured | 2002 |
Identical chemotherapy schedules given on and off trial protocol in small cell lung cancer: response and survival results.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Topic; Clinical Trials, Phase III as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Life Tables; Lung Neoplasms; Male; Middle Aged; Patient Acceptance of Health Care; Patient Selection; Prognosis; Randomized Controlled Trials as Topic; Remission Induction; Retrospective Studies; Survival Analysis; Treatment Refusal | 2002 |
Tirapazamine: a hypoxia-activated topoisomerase II poison.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Hypoxia; DNA Damage; DNA Topoisomerases, Type II; DNA, Neoplasm; Enzyme Inhibitors; Etoposide; HeLa Cells; Humans; Lung Neoplasms; Tirapazamine; Topoisomerase II Inhibitors; Triazines | 2002 |
Expression of inhibitor of apoptosis proteins in small- and non-small-cell lung carcinoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Fractionation; Etoposide; Gamma Rays; Humans; Inhibitor of Apoptosis Proteins; Lung Neoplasms; Proteins; Tumor Cells, Cultured; Ubiquitin-Protein Ligases; X-Linked Inhibitor of Apoptosis Protein | 2002 |
Small-cell lung cancer, high growth rate, high response rate to chemotherapy: ideal for high-dose chemotherapy?
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Survival Analysis | 2002 |
[Outpatient chemotherapy for small cell lung cancer in our hospital].
Topics: Aged; Aged, 80 and over; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Survival Analysis; Treatment Outcome | 2002 |
Superior vena cava syndrome caused by chemotherapy-induced fibrosis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Fibrosis; Follow-Up Studies; Humans; Lung Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Superior Vena Cava Syndrome; Vena Cava, Superior | 2002 |
[Localization of primary small cell carcinoma with liver metastasis: a rare combination of colonic adenocarcinoma and undifferentiated small cell carcinoma].
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Colectomy; Colon; Colonic Neoplasms; Docetaxel; Doxorubicin; Etoposide; Female; Humans; Immunohistochemistry; Liver; Liver Neoplasms; Neoplasms, Multiple Primary; Neoplasms, Unknown Primary; Paclitaxel; Taxoids; Time Factors; Vincristine | 2002 |
Effectiveness of preoperative chemotherapy using carboplatin (CBDCA) and surgery against an esophageal small cell carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Carboplatin; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Esophageal Neoplasms; Esophagectomy; Esophagoscopy; Etoposide; Follow-Up Studies; Humans; Immunohistochemistry; Lymph Nodes; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Preoperative Care; Tomography, X-Ray Computed; Treatment Outcome | 2002 |
Inhibition of phosphatidylinositol 3-kinase-Akt signaling blocks growth, promotes apoptosis, and enhances sensitivity of small cell lung cancer cells to chemotherapy.
Topics: Alleles; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Carcinoma, Small Cell; Cell Death; Cell Division; Cell Survival; Chromones; Doxycycline; Enzyme Inhibitors; Etoposide; Genes, Dominant; Genetic Vectors; Humans; In Situ Nick-End Labeling; Inhibitory Concentration 50; Insulin-Like Growth Factor I; Lung Neoplasms; Morpholines; Mutation; Phosphoinositide-3 Kinase Inhibitors; Precipitin Tests; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Stem Cell Factor; Time Factors; Tumor Cells, Cultured | 2002 |
[Small cell carcinoma of the prostate: a case report].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Fatal Outcome; Humans; Male; Prostatic Neoplasms; Radiotherapy, Adjuvant | 2002 |
"The guard dies, it does not surrender!" progress in the management of small-cell lung cancer?
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Epirubicin; Etoposide; Humans; Lung Neoplasms; Vincristine | 2002 |
[Early irradiation with radiochemotherapy for limited-stage small cell lung cancer is superior to late irradiation].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Etoposide; Humans; Lung Neoplasms; Neoplasm Staging; Outcome and Process Assessment, Health Care; Randomized Controlled Trials as Topic; Survival Rate | 2002 |
[New data presented at ASCO 2002 concerning small cell bronchial cancer].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Carboplatin; Carcinoma, Small Cell; Cisplatin; Deoxycytidine; Etoposide; Gemcitabine; Humans; Imatinib Mesylate; Lung Neoplasms; Piperazines; Prognosis; Pyrimidines; Quinolones; Smoking; Smoking Prevention; Survival Analysis; Treatment Outcome | 2002 |
Use of temozolomide with other cytotoxic chemotherapy in the treatment of patients with recurrent brain metastases from lung cancer.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Combined Modality Therapy; Dacarbazine; Etoposide; Female; Humans; Lung Neoplasms; Middle Aged; Prognosis; Temozolomide; Treatment Outcome | 2003 |
Chemotherapy for elderly SCLC patients.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Clinical Trials as Topic; Etoposide; Humans; Lung Neoplasms; Treatment Outcome | 2003 |
Shorter is not better.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Etoposide; Humans; Lung Neoplasms; Lymphoma, Non-Hodgkin; Survival Analysis; Treatment Outcome | 2003 |
Small cell carcinoma of the esophagus with reference to alternating multiagent chemotherapy: report of two cases.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Brain Neoplasms; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Fatal Outcome; Female; Humans; Liver Neoplasms; Male; Middle Aged; Peptide Fragments; Vincristine | 2003 |
DNA repair rate and etoposide (VP16) resistance of tumor cell subpopulations derived from a single human small cell lung cancer.
Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Small Cell; DNA Damage; DNA Repair; DNA Topoisomerases, Type II; DNA-Activated Protein Kinase; DNA-Binding Proteins; DNA, Neoplasm; Drug Resistance, Neoplasm; Endodeoxyribonucleases; Etoposide; Exodeoxyribonucleases; Humans; Lung Neoplasms; Nuclear Proteins; Protein Serine-Threonine Kinases; Rad51 Recombinase; Saccharomyces cerevisiae Proteins; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2003 |
The role of RAD51 in etoposide (VP16) resistance in small cell lung cancer.
Topics: Carcinoma, Small Cell; DNA Repair; DNA-Activated Protein Kinase; DNA-Binding Proteins; Drug Resistance, Neoplasm; Etoposide; Humans; Lung Neoplasms; Nuclear Proteins; Protein Serine-Threonine Kinases; Rad51 Recombinase; Tumor Cells, Cultured | 2003 |
[Thymic carcinoma (mixed small cell undifferentiated squamous cell carcinoma); report of a case].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Etoposide; Humans; Male; Neoplasms, Multiple Primary; Thymectomy; Thymus Neoplasms | 2003 |
Modified Ifosphamide/CarboPlatin/Etoposide.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Humans; Ifosfamide; Lung Neoplasms; Neoplasm Staging; Patient Selection; Prognosis; Randomized Controlled Trials as Topic | 2003 |
[Marked improvement of Lambert-Eaton myasthenic syndrome resulting from treatment for small cell lung carcinoma].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Drug Administration Schedule; Etoposide; Humans; Inappropriate ADH Syndrome; Lambert-Eaton Myasthenic Syndrome; Lung Neoplasms; Male | 2003 |
Modulation of drug and radiation resistance in small cell lung cancer cells by paclitaxel.
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Small Cell; Cisplatin; Drug Resistance, Neoplasm; Etoposide; Glutathione; Humans; Lung Neoplasms; Paclitaxel; Tumor Cells, Cultured | 2003 |
Small-cell carcinoma of the cervix: fourteen years of experience at a single institution using a combined-modality regimen of involved-field irradiation and platinum-based combination chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Etoposide; Female; Humans; Middle Aged; Paclitaxel; Radiotherapy Dosage; Survival Rate; Uterine Cervical Neoplasms | 2003 |
[Maintenance chemotherapy for small-cell lung cancer. A new publication].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Etoposide; Humans; Ifosfamide; Lung Neoplasms; Practice Guidelines as Topic; Randomized Controlled Trials as Topic | 2003 |
Using technetium-99m methoxyisobutylisonitrile lung single-photon-emission computed tomography to predict response to chemotherapy and compare with P-glycoprotein expression in patients with untreated small cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Radiopharmaceuticals; Retrospective Studies; Technetium Tc 99m Sestamibi; Tomography, Emission-Computed, Single-Photon | 2003 |
Shifting from hypofractionated to "conventionally" fractionated thoracic radiotherapy: a single institution's 10-year experience in the management of limited-stage small-cell lung cancer using concurrent chemoradiation.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Dose Fractionation, Radiation; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Multivariate Analysis; Neoplasm Staging; Retrospective Studies; Survival Rate; Vincristine | 2003 |
Kit expression in small cell carcinomas of the lung: effects of chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Follow-Up Studies; Humans; Immunoenzyme Techniques; Lung Neoplasms; Male; Middle Aged; Proto-Oncogene Mas; Proto-Oncogene Proteins c-kit; Survival Rate | 2003 |
Fibroblast growth factor 2-mediated translational control of IAPs blocks mitochondrial release of Smac/DIABLO and apoptosis in small cell lung cancer cells.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Small Cell; Carrier Proteins; Caspases; Cell Death; Cell Line, Tumor; Culture Media, Serum-Free; Cytochromes c; Enzyme Activation; Etoposide; Fibroblast Growth Factor 2; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 1; Mitochondria; Mitochondrial Proteins; Mitogen-Activated Protein Kinase Kinases; Nucleic Acid Synthesis Inhibitors; Protein Biosynthesis; Protein Serine-Threonine Kinases; Proteins; X-Linked Inhibitor of Apoptosis Protein | 2003 |
Topotecan as first-line therapy for small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Carcinoma, Small Cell; Cisplatin; Etoposide; Forecasting; Humans; Lung Neoplasms; Paclitaxel; Platinum; Topotecan | 2003 |
Options for first- and second-line therapy in small cell lung cancer--a workshop discussion.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Etoposide; Humans; Lung Neoplasms; Neoplasm Recurrence, Local | 2003 |
[The role of surgical therapy for esophageal microcytoma. Experience of there clinical cases and results analysis].
Topics: Aged; Anastomosis, Surgical; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Combined Modality Therapy; Esophageal Neoplasms; Esophagectomy; Esophagoplasty; Esophagoscopy; Etoposide; Fatal Outcome; Female; Humans; Laparotomy; Lymph Node Excision; Male; Middle Aged; Mitomycin; Remission Induction; Stomach; Thoracotomy; Vinblastine; Vinorelbine | 2003 |
Primary small cell carcinoma of the common bile duct, in which surgical treatment was performed after neoadjuvant chemotherapy: report of a case.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Common Bile Duct Neoplasms; Etoposide; Follow-Up Studies; Humans; Immunohistochemistry; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Pancreaticoduodenectomy; Risk Assessment; Treatment Outcome | 2003 |
Combined therapy with a new bisphosphonate, minodronate (YM529), and chemotherapy for multiple organ metastases of small cell lung cancer cells in severe combined immunodeficient mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Bone Neoplasms; Carcinoma, Small Cell; Cell Division; Diphosphonates; Drug Combinations; Etoposide; Humans; Imidazoles; Kidney Neoplasms; Killer Cells, Natural; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Mice; Mice, Inbred ICR; Mice, SCID; Osteoclasts; Parathyroid Hormone-Related Protein; Survival Rate; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A | 2003 |
Cytomegalovirus colitis--a severe complication after standard chemotherapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Colitis; Cytomegalovirus Infections; Etoposide; Humans; Lung Neoplasms; Male | 2002 |
Pharmacokinetic analysis of combination chemotherapy with carboplatin and etoposide in small-cell lung cancer patients undergoing hemodialysis.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Female; Humans; Kidney Failure, Chronic; Lung Neoplasms; Male; Middle Aged; Renal Dialysis | 2004 |
[Alternating electric heart axis in a patient with small cell lung cancer].
Topics: Abdominal Pain; Antineoplastic Agents; Carboplatin; Carcinoma, Small Cell; Echocardiography; Electrocardiography; Etoposide; Heart Conduction System; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Pericardial Effusion; Pericardiocentesis | 2004 |
[Tumor staging with PET/CT. Detection of a second tumor].
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Biopsy; Bronchoscopy; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Etoposide; Humans; Hypopharyngeal Neoplasms; Hypopharynx; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Neoplasms, Second Primary; Radiography, Thoracic; Radiotherapy, Adjuvant; Tomography, Emission-Computed; Tomography, X-Ray Computed | 2004 |
[Lambert-Eaton myasthenic syndrome with acute respiratory failure associated with small cell lung cancer].
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bronchoscopy; Carcinoma, Small Cell; Cisplatin; Diagnosis, Differential; Electromyography; Etoposide; Fatal Outcome; Female; Humans; Immunization, Passive; Inappropriate ADH Syndrome; Lambert-Eaton Myasthenic Syndrome; Lung; Lung Neoplasms; Middle Aged; Neurologic Examination; Palliative Care; Respiratory Insufficiency; Tomography, X-Ray Computed | 2004 |
Use of a cholesterol-rich microemulsion that binds to low-density lipoprotein receptors as vehicle for etoposide.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Small Cell; Chromatography, High Pressure Liquid; Emulsions; Etoposide; Lethal Dose 50; Lung Neoplasms; Mice; Mice, Inbred C57BL; Receptors, LDL; Structure-Activity Relationship; Tumor Cells, Cultured | 2003 |
RasGTPase-activating protein is a target of caspases in spontaneous apoptosis of lung carcinoma cells and in response to etoposide.
Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Caspases; Cell Line, Tumor; Enzyme Activation; Etoposide; Humans; Lung Neoplasms; ras GTPase-Activating Proteins | 2004 |
Down-regulation of Bcl-2 is associated with cisplatin resistance in human small cell lung cancer H69 cells.
Topics: Acetophenones; Antineoplastic Agents, Phytogenic; Apoptosis; Benzopyrans; Blotting, Western; Carcinoma, Small Cell; Caspase 3; Caspase 9; Caspases; Cell Death; Cell Line, Tumor; Cisplatin; Down-Regulation; Drug Resistance, Neoplasm; Enzyme Activation; Enzyme Inhibitors; Etoposide; Flow Cytometry; Humans; Immunoblotting; Lung Neoplasms; Membrane Potentials; Mitochondria; Paclitaxel; Phosphorylation; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; Time Factors | 2004 |
Mantle cell lymphoma in lymph nodes with metastatic small cell carcinoma of lung: a diagnostic and treatment dilemma.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antigens, CD20; Carcinoma, Small Cell; CD3 Complex; Cisplatin; Etoposide; Female; Humans; Immunohistochemistry; In Situ Hybridization, Fluorescence; Lung Neoplasms; Lymph Nodes; Lymphatic Metastasis; Lymphoma, Mantle-Cell; Middle Aged; Remission Induction; Rituximab | 2004 |
Stage IIIC small cell carcinoma of the ovary: survival with conservative surgery and chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Fallopian Tubes; Female; Humans; Neoplasm Staging; Ovarian Neoplasms; Ovariectomy; Vinblastine | 2004 |
Population-based outcomes for SCLC.
Topics: Administration, Oral; Antineoplastic Agents; Carcinoma, Small Cell; Etoposide; Humans; Lung Neoplasms; Outcome Assessment, Health Care | 2004 |
[Chemotherapy for small cell lung cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Irinotecan; Lung Neoplasms | 2004 |
Endogenously released Smac is insufficient to mediate cell death of human lung carcinoma in response to etoposide.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carrier Proteins; Caspases; Cell Line, Tumor; Cell Membrane; Cytochromes c; DNA Fragmentation; Down-Regulation; Etoposide; HeLa Cells; High-Temperature Requirement A Serine Peptidase 2; Humans; Inhibitor of Apoptosis Proteins; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Membrane Potentials; Mitochondria; Mitochondrial Proteins; Peptides; Protein Transport; Proteins; RNA, Small Interfering; Serine Endopeptidases | 2004 |
[Tumor lysis syndrome after chemotherapy for colon small cell carcinoma].
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Colectomy; Colonic Neoplasms; Combined Modality Therapy; Etoposide; Female; Hearing Loss; Humans; Liver Neoplasms; Middle Aged; Postoperative Care; Tumor Lysis Syndrome | 2004 |
[A case of cT0N2M0 small cell lung cancer with Lambert-Eaton myasthenic syndrome].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Autoantibodies; Calcium Channels; Carboplatin; Carcinoma, Small Cell; Electromyography; Etoposide; Humans; Lambert-Eaton Myasthenic Syndrome; Lung Neoplasms; Male | 2004 |
[A case report of esophageal small cell carcinoma: a long-term survival by radio-chemotherapy with carboplatin and etoposide].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Drug Administration Schedule; Esophageal Neoplasms; Etoposide; Humans; Male; Middle Aged; Radiotherapy, High-Energy; Remission Induction; Survivors | 2004 |
[Clinical pathway based on evidence-based medicine (EBM) for chemotherapy for lung cancer].
Topics: Acute Kidney Injury; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Critical Pathways; Etoposide; Evidence-Based Medicine; Female; Humans; Irinotecan; Leukopenia; Lung Neoplasms; Male; Middle Aged; Vomiting | 2004 |
Small cell carcinoma of bladder: a single-center prospective study of 25 cases treated in analogy to small cell lung cancer.
Topics: Age Factors; Aged; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Comorbidity; Cyclophosphamide; Cystectomy; Doxorubicin; Etoposide; Feasibility Studies; Female; Humans; Ifosfamide; Male; Methotrexate; Middle Aged; Palliative Care; Prognosis; Prospective Studies; Radiotherapy, Adjuvant; Survival Analysis; Treatment Outcome; Urinary Bladder Neoplasms; Vinblastine | 2005 |
Double-platinum chemotherapy combined with etoposide in metastatic brain tumor from small cell lung carcinoma.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antineoplastic Protocols; Brain Neoplasms; Carboplatin; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Etoposide; Humans; Lung Neoplasms; Male; Middle Aged; Radiotherapy, Adjuvant; Treatment Outcome | 2005 |
The insulin-like growth factor-I receptor kinase inhibitor, NVP-ADW742, sensitizes small cell lung cancer cell lines to the effects of chemotherapy.
Topics: Antineoplastic Agents; Apoptosis; Carboplatin; Carcinoma, Small Cell; Cell Division; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Etoposide; Gene Expression Regulation, Neoplastic; Humans; In Situ Nick-End Labeling; Insulin-Like Growth Factor I; Lung Neoplasms; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Receptor, IGF Type 1; RNA, Messenger; Vascular Endothelial Growth Factor A | 2005 |
CXCR4 chemokine receptor and integrin signaling co-operate in mediating adhesion and chemoresistance in small cell lung cancer (SCLC) cells.
Topics: Apoptosis; Carcinoma, Small Cell; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Chemokine CXCL12; Chemokines, CXC; Collagen; Drug Resistance, Neoplasm; Etoposide; Fibronectins; Humans; Integrins; Lung Neoplasms; Peptides; Phosphotyrosine; Receptors, CXCR4; rho GTP-Binding Proteins; Signal Transduction | 2005 |
'Successful' chemo- and radiotherapy prior to radical cystectomy does not necessarily correlate with clinical course in small cell carcinoma of the bladder.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cystectomy; Doxorubicin; Etoposide; Follow-Up Studies; Humans; Male; Preoperative Care; Treatment Outcome; Urinary Bladder Neoplasms | 2005 |
Cytogenetic damage in lymphocytes of patients undergoing therapy for small cell lung cancer and ovarian carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Dose-Response Relationship, Drug; Etoposide; Female; Humans; Kinetics; Leukocyte Count; Lung Neoplasms; Lymphocytes; Male; Micronuclei, Chromosome-Defective; Micronucleus Tests; Middle Aged; Ovarian Neoplasms; Paclitaxel | 2005 |
Primary small-cell carcinoma of the breast.
Topics: Antineoplastic Agents; Axilla; Breast Neoplasms; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Lymph Node Excision; Mastectomy, Segmental; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Postmenopause; Radiotherapy; Treatment Outcome | 2005 |
Efficacy of two different platinum- or anthracycline-containing chemotherapy regimens for the treatment of small cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Chi-Square Distribution; Epirubicin; Etoposide; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Probability; Proportional Hazards Models; Retrospective Studies; Risk Assessment; Survival Analysis; Treatment Outcome | 2005 |
Hypopharyngeal small cell carcinoma: a case report.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Female; Humans; Hypopharyngeal Neoplasms; Photomicrography; Tomography, X-Ray Computed; Treatment Outcome | 2005 |
[Chemotherapy in extended small-cell lung cancer. Retrospective analysis of two different series of patients treated with carboplatin and etoposide or ciclophosphamide-epidoxorubicin and etoposide].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Epirubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Retrospective Studies | 2005 |
Ramifications of severe organ dysfunction in newly diagnosed patients with small cell lung cancer: contemporary experience from a single institution.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bilirubin; Carboplatin; Carcinoma, Small Cell; Cisplatin; Creatinine; Cyclophosphamide; Decision Making; Etoposide; Female; Humans; Lung Neoplasms; Male; Medical Records; Middle Aged; Multiple Organ Failure; Neoplasm Staging; Paclitaxel; Platelet Count; Survival Rate; Treatment Outcome | 2005 |
Clinical responses of large cell neuroendocrine carcinoma of the lung to cisplatin-based chemotherapy.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Large Cell; Carcinoma, Neuroendocrine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Mitomycin; Neoplasm Staging; Treatment Outcome; Vindesine | 2005 |
[Small cell carcinoma of the urinary bladder: a case report].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Carcinoma, Transitional Cell; Cisplatin; Combined Modality Therapy; Etoposide; Female; Humans; Lymph Nodes; Lymphatic Metastasis; Urinary Bladder Neoplasms | 2005 |
Prophylactic cranial irradiation in limited-stage small-cell lung cancer: a retrospective analysis.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Etoposide; Female; Hospitals, Community; Humans; Lung Neoplasms; Male; Middle Aged; North Dakota; Paclitaxel; Prognosis; Remission Induction; Retrospective Studies; Treatment Outcome; Treatment Refusal | 2004 |
Potent inhibition of small-cell lung cancer cell growth by simvastatin reveals selective functions of Ras isoforms in growth factor signalling.
Topics: Animals; Antineoplastic Agents, Phytogenic; Base Sequence; Carcinoma, Small Cell; Cell Proliferation; Etoposide; Extracellular Signal-Regulated MAP Kinases; Growth Substances; Humans; Lung Neoplasms; MAP Kinase Kinase Kinases; Membrane Microdomains; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-kit; ras Proteins; Signal Transduction; Simvastatin; Tumor Cells, Cultured; Up-Regulation | 2006 |
[Combined radiochemotherapy in localised small-cell lung cancer. Concurrent treatment protocols?].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Disease-Free Survival; Esophagitis; Etoposide; Humans; Lung Neoplasms; Male; Middle Aged; Neutropenia; Radiation Pneumonitis; Radiotherapy; Remission Induction; Retrospective Studies; Survival Analysis; Treatment Outcome | 2005 |
[Small cell carcinoma of the bladder: a case report].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Carcinoma, Transitional Cell; Combined Modality Therapy; Cystectomy; Drug Administration Schedule; Etoposide; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasms, Multiple Primary; Urinary Bladder Neoplasms; Urinary Diversion | 2005 |
Is radiotherapy optimally combined with chemotherapy in elderly patients with limited-stage small-cell lung cancer?
Topics: Aged; Antineoplastic Agents; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Etoposide; Humans; Lung Neoplasms; Middle Aged; Treatment Outcome | 2005 |
ECM overrides DNA damage-induced cell cycle arrest and apoptosis in small-cell lung cancer cells through beta1 integrin-dependent activation of PI3-kinase.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Small Cell; Cell Adhesion; Cell Cycle; Cell Line, Tumor; DNA Damage; Etoposide; Extracellular Matrix; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Integrin beta1; Laminin; Lung Neoplasms; Mutation; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Vanadates | 2006 |
[A case of small-cell lung cancer effectively treated by bi-weekly administration of amrubicin].
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Camptothecin; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Etoposide; Humans; Irinotecan; Lung Neoplasms; Male; Middle Aged | 2006 |
Third-line chemotherapy for small cell lung cancer.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Retrospective Studies; Salvage Therapy; Survival Rate; Time Factors | 2006 |
Reponses to topoisomerase-I inhibitors in extensive small-cell lung cancer: chance or chromosomes?
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Enzyme Inhibitors; Etoposide; Humans; Lung Neoplasms; Topoisomerase I Inhibitors; Topotecan | 2006 |
Syndrome of inappropriate antidiuretic hormone secretion in a patient with cryptococcal meningoencephalitis: a hidden mediastinal small cell carcinoma.
Topics: Carcinoma, Small Cell; Cisplatin; Etoposide; Fluconazole; Humans; Hyponatremia; Inappropriate ADH Syndrome; Male; Mediastinal Neoplasms; Meningitis, Cryptococcal; Meningoencephalitis; Middle Aged; Positron-Emission Tomography | 2006 |
Cost effectiveness of increasing the dose intensity of chemotherapy with granulocyte colony-stimulating factor in small-cell lung cancer: based on data from the Medical Research Council LU19 trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cost-Benefit Analysis; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Middle Aged; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Retrospective Studies; State Medicine; Survival Analysis | 2006 |
Intravascular hemolysis as a complication of clostridium perfringens sepsis.
Topics: Anemia, Hemolytic; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Carcinoma, Small Cell; Cisplatin; Clostridium Infections; Clostridium perfringens; Etoposide; Hemolysis; Humans; Jaundice, Obstructive; Liver Neoplasms; Male; Middle Aged; Neuroendocrine Tumors; Pancreatic Neoplasms; Systemic Inflammatory Response Syndrome | 2006 |
Cisplatin plus etoposide chemotherapy followed by thoracic irradiation and paclitaxel plus cisplatin consolidation therapy for patients with limited stage small cell lung carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Etoposide; Female; Humans; Lung; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Paclitaxel; Survival Rate; Treatment Outcome | 2006 |
[From ASCO and WCLC 2005 to clinical practice: "conventional" treatments].
Topics: Administration, Oral; Age Factors; Aged; Angiogenesis Inhibitors; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Clinical Trials, Phase III as Topic; Deoxycytidine; Docetaxel; Etoposide; Follow-Up Studies; Gemcitabine; Humans; Irinotecan; Lung; Lung Neoplasms; Mediastinoscopy; Meta-Analysis as Topic; Middle Aged; Neoplasm Staging; Palliative Care; Pneumonectomy; Radiotherapy Dosage; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Taxoids; Time Factors; Topotecan | 2006 |
[Collision cancer of squamous cell carcinoma and small cell carcinoma of the lung; report of a case].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Etoposide; Humans; Irinotecan; Lung Neoplasms; Lymph Node Excision; Male; Neoplasms, Multiple Primary; Pneumonectomy | 2006 |
FGF-2 protects small cell lung cancer cells from apoptosis through a complex involving PKCepsilon, B-Raf and S6K2.
Topics: Antineoplastic Agents; Apoptosis; bcl-X Protein; Carcinoma, Small Cell; Cell Line; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Etoposide; Extracellular Signal-Regulated MAP Kinases; Fibroblast Growth Factor 2; Humans; Lung Neoplasms; Phosphorylation; Protein Kinase C-epsilon; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-raf; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; X-Linked Inhibitor of Apoptosis Protein | 2006 |
Small-cell lung cancer with lymphadenopathy in an 18-year-old female nonsmoker.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Diagnosis, Differential; Etoposide; Female; Humans; Lung Neoplasms; Lymph Node Excision; Lymphatic Diseases; Lymphatic Metastasis; Mediastinal Neoplasms; Neoplasm Staging; Pneumonectomy; Radiotherapy, Adjuvant; Smoking | 2006 |
[A case of inoperable gastric small cell carcinoma effectively treated by chemotherapy and radiotherapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Drug Administration Schedule; Drug Combinations; Etoposide; Humans; Irinotecan; Lymph Nodes; Lymphatic Metastasis; Male; Oxonic Acid; Paclitaxel; Stomach Neoplasms; Tegafur | 2006 |
[Lung cancer with bone metastasis].
Topics: Analgesics; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Diphosphonates; Docetaxel; Drug Administration Schedule; Etoposide; Fractures, Bone; Gefitinib; Humans; Irinotecan; Lung Neoplasms; Paclitaxel; Pain, Intractable; Prognosis; Quinazolines; Radiotherapy Dosage; Taxoids | 2006 |
Thoracic radiation therapy in limited stage small-cell lung cancer: timing is everything...isn't it?
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Dose Fractionation, Radiation; Doxorubicin; Etoposide; Humans; London; Lung Neoplasms; Meta-Analysis as Topic; Multicenter Studies as Topic; Neoplasm Staging; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Survival Analysis; Time Factors; Treatment Outcome; Vincristine | 2006 |
Multidrug resistance in small cell lung cancer: expression of P-glycoprotein, multidrug resistance protein 1 and lung resistance protein in chemo-naive patients and in relapsed disease.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Small Cell; Cisplatin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Recurrence, Local; Prospective Studies; Vault Ribonucleoprotein Particles | 2006 |
Protocol consisting of cisplatin, etoposide and irinotecan induced complete pathological remission of primary small cell carcinoma of the bladder.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cisplatin; Etoposide; Humans; Irinotecan; Male; Neoadjuvant Therapy; Remission Induction; Urinary Bladder Neoplasms | 2006 |
[Chemotherapy treatment for anti-Hu paraneoplastic syndrome without active malignancy].
Topics: Antibodies; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Encephalitis; Etoposide; Humans; Infant; Lung Neoplasms; Male; Middle Aged; Paraneoplastic Cerebellar Degeneration; Treatment Outcome | 2006 |
The association of chemotherapy induced neutropenia on treatment outcomes in small cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Female; Fever; Humans; Lung Neoplasms; Male; Middle Aged; Neutropenia; Treatment Outcome | 2006 |
Influence of Bcl-2 family members on the cellular response of small-cell lung cancer cell lines to ABT-737.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Biphenyl Compounds; Carboplatin; Carcinoma, Small Cell; Cell Growth Processes; Cell Line, Tumor; Down-Regulation; Drug Synergism; Etoposide; Humans; Lung Neoplasms; Membrane Proteins; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Nitrophenols; Piperazines; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering; Sulfonamides; Transfection; Up-Regulation | 2007 |
Mid-course thoracic radiotherapy with cisplatin-etoposide chemotherapy in limited-stage small-cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Dose Fractionation, Radiation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Radiotherapy; Retrospective Studies; Survival Analysis; Survival Rate | 2006 |
[A case of recurrent Helicobacter cinaedi-associated bacteremia in a small cell lung cancer patient during chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Drug Administration Schedule; Etoposide; Helicobacter Infections; Humans; Immunocompromised Host; Lung Neoplasms; Male; Middle Aged; Recurrence | 2007 |
Identification of uPAR-positive chemoresistant cells in small cell lung cancer.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Neoplasms; Brain Neoplasms; Carcinoma, Small Cell; Cisplatin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Flow Cytometry; Fluorouracil; Humans; Hyaluronan Receptors; Lung Neoplasms; Neoplasm Proteins; Neoplastic Stem Cells; Phenotype; Receptors, Urokinase Plasminogen Activator; Tumor Cells, Cultured; Tumor Stem Cell Assay; Urokinase-Type Plasminogen Activator | 2007 |
Small cell carcinoma of the nasopharynx.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Carmustine; Cisplatin; Cyclophosphamide; Etoposide; Fatal Outcome; Humans; Male; Nasopharyngeal Neoplasms; Radiotherapy, Adjuvant | 2007 |
Addition of topotecan to standard cisplatin/etoposide combination in patients with extended stage small cell lung carcinoma.
Topics: Aged; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Etoposide; Feasibility Studies; Female; Follow-Up Studies; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Neutropenia; Survival Analysis; Thrombocytopenia; Time Factors; Topotecan | 2007 |
Adjuvant surgery after carboplatin and VP16 in resectable small cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Pneumonectomy; Positron-Emission Tomography; Prospective Studies; Survival Analysis | 2007 |
Syndrome of inappropriate antidiuretic hormone secretion and ectopic ACTH production in small cell lung carcinoma.
Topics: ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Female; Humans; Immunohistochemistry; Inappropriate ADH Syndrome; Lung Neoplasms; Middle Aged; Radiography; Remission Induction | 2007 |
[Outpatient chemotherapy for lung cancer].
Topics: Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Deoxycytidine; Docetaxel; Drug Administration Schedule; Etoposide; Gefitinib; Gemcitabine; Humans; Informed Consent; Irinotecan; Lung Neoplasms; Neutropenia; Paclitaxel; Quality of Life; Quinazolines; Taxoids; Vinblastine; Vinorelbine | 2007 |
Unexpected dementia following prophylactic cranial irradiation for small cell lung cancer: case report.
Topics: Aged; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Carboplatin; Carcinoma, Small Cell; Central Nervous System Neoplasms; Combined Modality Therapy; Dementia; Etoposide; Female; Humans; Lung Neoplasms; Memory Disorders; Radiotherapy | 2007 |
A case of small cell carcinoma of the kidney.
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Etoposide; Humans; Irinotecan; Kidney Neoplasms; Lymph Nodes; Lymphatic Metastasis; Male; Middle Aged; Piperidines | 2007 |
[Small-cell lung cancer diagnostic and therapeutic recommendations of Polish Lung Cancer Group].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Etoposide; Humans; Lung Neoplasms; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasms, Multiple Primary; Pneumonectomy; Prognosis; Remission Induction | 2007 |
Isolated metastasis of lung cancer to the thyroid gland.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Large Cell; Carcinoma, Small Cell; CD56 Antigen; Chemotherapy, Adjuvant; Chromogranin A; Cisplatin; Combined Modality Therapy; Etoposide; Humans; Irinotecan; Lung Neoplasms; Male; Thyroid Neoplasms | 2007 |
Combination of topotecan and etoposide as a salvage treatment for patients with recurrent small cell lung cancer following irinotecan and platinum first-line chemotherapy.
Topics: Aged; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Combined Modality Therapy; Endpoint Determination; Etoposide; Female; Hematologic Diseases; Humans; Irinotecan; Lung Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Patient Compliance; Salvage Therapy; Topotecan | 2008 |
Does small-cell phenotype predict the natural history of prostate cancer? A case study in disease behavior.
Topics: Adenocarcinoma; Androgen Antagonists; Anilides; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Docetaxel; Estramustine; Etoposide; Flutamide; Gonadotropin-Releasing Hormone; Humans; Male; Middle Aged; Nephrostomy, Percutaneous; Nitriles; Phenotype; Prostate-Specific Antigen; Prostatic Neoplasms; Taxoids; Tosyl Compounds; Transurethral Resection of Prostate; Urinary Diversion | 2007 |
Case report: clozapine given in the context of chemotherapy for lung cancer.
Topics: Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Antipsychotic Agents; Carcinoma, Small Cell; Cisplatin; Clozapine; Comorbidity; Cooperative Behavior; Drug Interactions; Etoposide; Humans; Leukocyte Count; Lung Neoplasms; Neoplasm Staging; Palliative Care; Patient Care Team; Quality of Life; Referral and Consultation; Remission Induction; Schizophrenia, Paranoid | 2008 |
Accelerated hyperfractionated radiotherapy and concomitant chemotherapy in small cell lung cancer limited-disease. Dose response, feasibility and outcome for patients treated in western Sweden, 1998-2004.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cause of Death; Combined Modality Therapy; Dose Fractionation, Radiation; Dose-Response Relationship, Radiation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Retrospective Studies; Survival Analysis; Sweden; Treatment Outcome | 2007 |
Advanced small cell carcinoma of the ovary in a seventeen-year-old female, successfully treated with surgery and multi-agent chemotherapy.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Bleomycin; Carcinoma, Small Cell; Celecoxib; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Imatinib Mesylate; Lymph Nodes; Lymphatic Metastasis; Ovarian Neoplasms; Piperazines; Pyrazoles; Pyrimidines; Sulfonamides; Thalidomide; Vinblastine | 2008 |
Successful treatment of small cell lung cancer during pregnancy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Lung Neoplasms; Pregnancy; Pregnancy Complications | 2008 |
[A case of long-term survival of postoperative brain metastasis of small cell lung cancer effectively treated with chemotherapy, whole brain radiotherapy and stereotactic radiosurgery].
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Irinotecan; Lung Neoplasms; Magnetic Resonance Imaging; Middle Aged; Radiosurgery; Time Factors; Tomography, X-Ray Computed | 2008 |
Costs associated with intravenous chemotherapy administration in patients with small cell lung cancer: a retrospective claims database analysis.
Topics: Administration, Oral; Aged; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carboplatin; Carcinoma, Small Cell; Cisplatin; Cost-Benefit Analysis; Cyclophosphamide; Doxorubicin; Etoposide; Female; Health Care Costs; Humans; Infusions, Intravenous; Insurance Claim Review; Irinotecan; Male; Middle Aged; Retrospective Studies; Topotecan; United States; Vincristine | 2008 |
[Chemotherapy of the small cell lung cancer using polyplatillen].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; DNA Adducts; Drug Administration Schedule; Etoposide; Female; Humans; Male; Middle Aged; Treatment Outcome | 2007 |
[A patient with small cell lung cancer who developed a drug eruption due to concomitant therapy with carboplatin and etoposide].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Drug Eruptions; Etoposide; Humans; Lung Neoplasms; Male | 2008 |
Small cell carcinoma of the gallbladder successfully treated by surgery and adjuvant chemotherapy.
Topics: Aged; Antineoplastic Agents; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Etoposide; Female; Gallbladder Neoplasms; Humans | 2008 |
Therapeutic efficacy of ABT-737, a selective inhibitor of BCL-2, in small cell lung cancer.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biphenyl Compounds; Carcinoma, Small Cell; Caspase 3; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Activation; Etoposide; Humans; Lung Neoplasms; Mice; Mice, Nude; Nitrophenols; Piperazines; Proto-Oncogene Proteins c-bcl-2; Sulfonamides; Xenograft Model Antitumor Assays | 2008 |
Caecal metastasis from a primary small-cell lung carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Brain Stem Neoplasms; Carboplatin; Carcinoma, Small Cell; Cecal Neoplasms; Cecum; Colonoscopy; Combined Modality Therapy; Cranial Irradiation; Etoposide; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged | 2008 |
Diseases desperate grown.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Humans; Ifosfamide; Lung Neoplasms; Randomized Controlled Trials as Topic; Research Design; Sample Size; Treatment Outcome | 2008 |
[Erythropoietic protein supportive treatment in small cell lung cancer].
Topics: Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Erythropoietin; Etoposide; Female; Hematinics; Hemoglobins; Humans; Lung Neoplasms; Male; Middle Aged; Retrospective Studies; Treatment Outcome | 2008 |
Prostate small cell carcinoma and skin metastases: a rare entity.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Fatal Outcome; Humans; Male; Middle Aged; Prognosis; Prostatic Neoplasms; Skin Neoplasms; Vincristine | 2008 |
Primary small cell carcinoma of the breast.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Camptothecin; Carboplatin; Carcinoma, Small Cell; Etoposide; Fatal Outcome; Female; Humans; Irinotecan; Liver Neoplasms; Mastectomy; Middle Aged; Neoplasm Recurrence, Local; Thoracic Wall | 2009 |
Cyclophosphamide and VP 16-213 with autologous bone marrow transplantation. A dose escalation study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasms; Neoplasms, Germ Cell and Embryonal; Ovarian Neoplasms; Transplantation, Autologous | 1984 |
[3 multicenter phase II studies of the treatment of small cell bronchogenic carcinoma (incl. AIO studies BI + BII)].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Evaluation; Etoposide; Female; Humans; Ifosfamide; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Vinblastine; Vincristine; Vindesine | 1984 |
[A combination chemotherapy consisting of vincristine, etoposide and cyclophosphamide (VEC) for small cell carcinoma of the lung].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Vincristine | 1984 |
Remission of brain metastases from small-cell lung cancer after high-dose chemotherapy.
Topics: Brain Neoplasms; Carcinoma, Small Cell; Etoposide; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1984 |
Pilot studies of superfractionated radiotherapy and combination chemotherapy in limited oat cell carcinoma of the bronchus.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Lomustine; Lung Neoplasms; Male; Middle Aged; Procarbazine; Radiotherapy Dosage; Vincristine | 1984 |
Phase II trial of etoposide in previously treated small cell carcinoma of the lung.
Topics: Carcinoma, Small Cell; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Podophyllotoxin | 1984 |
Feasibility of high dose VP 16-213 as single agent or in combination with cyclophosphamide and autologous bone marrow transplantation (ABMT).
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasms, Germ Cell and Embryonal; Podophyllotoxin | 1984 |
Adriamycin, cyclophosphamide, and etoposide (VP-16-213) in extensive-stage small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis | 1984 |
Cisplatin and etoposide combination in the treatment of bronchogenic carcinoma.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cisplatin; Etoposide; Humans; Lung Neoplasms; Middle Aged | 1984 |
Phase II trial of vindesine and VP16-213 in the palliation of poor-prognosis patients and elderly patients with small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Palliative Care; Prognosis; Vinblastine; Vindesine | 1984 |
Smoking abstinence and small cell lung cancer survival. An association.
Topics: Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Etoposide; Humans; Lung Neoplasms; Prognosis; Smoking; Thymosin; Vincristine | 1980 |
Chemotherapy versus chemoimmunotherapy for small-cell undifferentiated carcinoma of the lung.
Topics: Aged; Agranulocytosis; Alopecia; Antineoplastic Agents; BCG Vaccine; Brain Neoplasms; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nausea; Prognosis; Prospective Studies; Vomiting | 1980 |
Cis-dichlorodiammineplatinum (II) and VP 16-213 combination chemotherapy for non-small cell lung cancer.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cisplatin; Drug Evaluation; Drug Therapy, Combination; Etoposide; Female; Humans; Injections, Intravenous; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1981 |
VP-16-213 therapy in patients with small-cell carcinoma of the lung after failure on combination chemotherapy.
Topics: Adult; Aged; Carcinoma, Small Cell; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1981 |
Treatment of small cell carcinoma of lung with combined high dose mediastinal irradiation, whole brain prophylaxis and chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Mediastinal Neoplasms; Middle Aged; Radiotherapy, High-Energy; Vincristine | 1981 |
Possible enhancement of vincristine neuropathy by VP-16.
Topics: Aged; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Electrophysiology; Etoposide; Humans; Lung Neoplasms; Male; Middle Aged; Muscles; Nervous System Diseases; Peripheral Nerves; Podophyllotoxin; Vincristine | 1982 |
Tumor size, response rate, and prognosis in small cell carcinoma of the bronchus treated by combination chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Small Cell; Cyclophosphamide; Drug Therapy, Combination; Etoposide; Female; Humans; Inappropriate ADH Syndrome; Leucovorin; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged | 1982 |
Alternating non-cross-resistant combination chemotherapy for small cell anaplastic carcinoma of the lung.
Topics: Antineoplastic Agents; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Etoposide; Humans; Lung Neoplasms; Methotrexate; Vincristine | 1982 |
Non-cross-resistant chemotherapy and consolidation radiotherapy for small cell carcinoma of the lung.
Topics: Adult; Aged; Altretamine; Antineoplastic Agents; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Prognosis; Vincristine | 1982 |
Epipodophyllotoxin (VP16-213) in small cell carcinoma of the Bronchus resistant to initial combination chemotherapy.
Topics: Bronchial Neoplasms; Carcinoma, Small Cell; Drug Resistance; Drug Therapy, Combination; Etoposide; Humans; Podophyllotoxin | 1982 |
Treatment of small cell lung cancer with a combination of VP16-213 and cyclophosphamide with cisplatin or radiotherapy.
Topics: Adult; Aged; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Time Factors | 1982 |
Vincristine, Adriamycin, cyclophosphamide, and etoposide (VP16-213) in small-cell anaplastic carcinoma of the lung.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Vincristine | 1982 |
VP16-213 combined with cis-platinum (CDDP) in the treatment of small cell carcinoma of the lung (SCLC).
Topics: Adult; Aged; Carcinoma, Small Cell; Cisplatin; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1982 |
Chemotherapy combination with cyclophosphamide (CTX) adriamycin (ADM), vincristine (VCR), and VP16-213 in small cell carcinoma of the lung (SCCL).
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Hematologic Diseases; Humans; Lung Neoplasms; Male; Middle Aged; Vincristine | 1982 |
Cisplatin, adriamycin, and etoposide (CAV) for remission induction of small-cell bronchogenic carcinoma.
Topics: Adult; Aged; Agranulocytosis; Bone Marrow Transplantation; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Leukocyte Count; Male; Middle Aged; Pilot Projects; Podophyllotoxin; Thrombocytopenia | 1982 |
[Prevention of recurrence of small-cell lung cancer by adjuvant polychemotherapy (author's transl)].
Topics: Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Humans; Ifosfamide; Lomustine; Lung Neoplasms; Methotrexate; Neoplasm Recurrence, Local; Vincristine | 1982 |
Enhanced radiation reaction following combination chemotherapy for small cell carcinoma of the lung, possibly secondary to VP16-213.
Topics: Aged; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Etoposide; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Radiotherapy; Vincristine | 1982 |
VP16-213 in combined modality treatment of small cell carcinoma of the lung.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Etoposide; Humans; Lung Neoplasms; Methotrexate; Nausea; Neoplasm Staging; Podophyllotoxin | 1982 |
Small-cell bronchogenic carcinoma--primary and relapse therapy with etoposide (VP-16), methotrexate and CCNU.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Drug Therapy, Combination; Etoposide; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Podophyllotoxin | 1982 |
Etoposide after ACO treatment for small-cell bronchogenic carcinoma.
Topics: Aged; Antineoplastic Agents; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Middle Aged; Podophyllotoxin; Vincristine | 1982 |
Etoposide as single agent and in combination chemotherapy of bronchogenic carcinoma.
Topics: Antineoplastic Agents; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Cisplatin; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1982 |
Combination cis-platinum and etoposide in small-cell lung cancer.
Topics: Adult; Aged; Carcinoma, Small Cell; Cisplatin; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1982 |
Combination chemotherapy of small-cell bronchogenic carcinoma with etoposide (VP-16), ifosfamide and vindesine (VPIV), and with adriamycin, cis-platinum and vincristine (APO).
Topics: Antineoplastic Agents; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Podophyllotoxin; Vinblastine; Vincristine; Vindesine | 1982 |
Small cell lung cancer. Serial bronchofiberscopy and photographic documentation--the bridge sign.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bronchoscopy; Carcinoma, Small Cell; Cicatrix; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Etoposide; Fiber Optic Technology; Humans; Ifosfamide; Lomustine; Lung Neoplasms; Methotrexate; Prospective Studies; Vincristine | 1983 |
VP-16 plus cyclophosphamide in the treatment of advanced lung cancer.
Topics: Adult; Aged; Carcinoma, Small Cell; Cyclophosphamide; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Probability | 1983 |
[Late intensive chemotherapy with bone marrow autograft. Pilot study in small cell bronchial cancer].
Topics: Adult; Antineoplastic Agents; Bone Marrow Transplantation; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Pilot Projects | 1983 |
High-dose chemotherapy and autologous bone marrow transplantation for the treatment of small cell lung carcinoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Arrhythmias, Cardiac; Bone Marrow Transplantation; Brain Neoplasms; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Vincristine | 1983 |
Etoposide in small cell lung cancer resistant to prior chemotherapy.
Topics: Carcinoma, Small Cell; Drug Resistance; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1983 |
High-dose etoposide as single-agent chemotherapy for small cell carcinoma of the lung.
Topics: Adult; Aged; Carcinoma, Small Cell; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1983 |
VP-16 alone and in combination with cisplatin in previously treated patients with small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Evaluation; Etoposide; Female; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Thrombocytopenia; Time Factors | 1984 |
Penetration of VP 16-213 into cerebrospinal fluid after high-dose intravenous administration.
Topics: Adult; Aged; Blood-Brain Barrier; Brain Neoplasms; Carcinoma, Small Cell; Drug Evaluation; Etoposide; Humans; Injections, Intravenous; Lung Neoplasms; Middle Aged; Podophyllotoxin; Tomography, X-Ray Computed | 1984 |
Effects of intensive induction chemotherapy for extensive-disease small cell bronchogenic carcinoma in protected environment-prophylactic antibiotic units.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Environment, Controlled; Etoposide; Female; Humans; Ifosfamide; Leukocyte Count; Lung Neoplasms; Male; Mediastinal Neoplasms; Methotrexate; Middle Aged; Procarbazine; Vincristine | 1984 |
[Multidisciplinary treatment for small cell lung cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Mitomycin; Mitomycins; Nimustine; Nitrosourea Compounds; Vincristine | 1984 |
Cyclic alternating combination chemotherapy for small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Time Factors; Vincristine | 1984 |
Etoposide (VP 16-213; VePesid).
Topics: Carcinoma, Small Cell; Etoposide; Humans; Lung Neoplasms; Male; Podophyllotoxin; Testicular Neoplasms | 1984 |
[Effects of oral etoposide in small cell carcinoma of the lung].
Topics: Administration, Oral; Adult; Aged; Capsules; Carcinoma, Small Cell; Etoposide; Humans; Leukopenia; Lung Neoplasms; Male; Nausea; Podophyllotoxin; Thrombocytopenia | 1984 |
Etoposide infusions for treatment of metastatic lung cancer.
Topics: Carcinoma, Small Cell; Chromatography, High Pressure Liquid; Etoposide; Follow-Up Studies; Humans; Infusions, Parenteral; Kinetics; Lung Neoplasms; Neoplasm Metastasis; Podophyllotoxin | 1984 |
Experimental basis and clinical experience with non-cross-resistant combinations in solid tumours.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Carcinoma, Ehrlich Tumor; Carcinoma, Small Cell; Cell Line; Cisplatin; Cyclophosphamide; Dacarbazine; Doxorubicin; Drug Administration Schedule; Drug Resistance; Etoposide; Humans; Ifosfamide; Male; Naphthacenes; Sarcoma; Teratoma; Testicular Neoplasms; Vinca Alkaloids; Vincristine | 1984 |
[Treatment of bronchopulmonary small cell carcinoma with a combination of cyclophosphamide and VP-16].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1984 |
Patient with extensive small cell lung cancer given moderately dose-intensified chemotherapy and peripheral blood stem cell support.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Fatal Outcome; Hematopoietic Stem Cell Transplantation; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Vincristine | 1995 |
[Lhermitte's sign and cancer].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Head; Humans; Lung Neoplasms; Male; Movement; Radiotherapy, Adjuvant | 1995 |
Long-term survival associated with metastatic small cell carcinoma of the esophagus treated by chemotherapy, autologous bone marrow transplantation, and adjuvant radiation therapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carboplatin; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Esophageal Neoplasms; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Liver Neoplasms; Lymphatic Metastasis; Melphalan; Prognosis; Radiotherapy Dosage; Transplantation, Autologous; Vincristine | 1994 |
The feasibility of using glycosylated recombinant human granulocyte colony-stimulating factor (G-CSF) to increase the planned dose intensity of doxorubicin, cyclophosphamide and etoposide (ACE) in the treatment of small cell lung cancer. Medical Research
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Feasibility Studies; Female; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Middle Aged; Neutropenia; Palliative Care; Thrombocytopenia | 1995 |
Etoposide protein binding in cancer patients.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Agents, Phytogenic; Carcinoma, Small Cell; Chromatography, High Pressure Liquid; Drug Administration Schedule; Etoposide; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasms; Ovarian Neoplasms; Protein Binding; Regression Analysis | 1995 |
Early alternating chemotherapy and radiotherapy schedule in limited disease stage small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Survival Analysis; Treatment Outcome | 1995 |
Chemotherapy of human small-cell gastrointestinal carcinoma xenografts in nude mice.
Topics: Aged; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Esophageal Neoplasms; Etoposide; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Mitomycin; Neoplasm Transplantation; Phosphopyruvate Hydratase; Remission Induction; Stomach Neoplasms; Transplantation, Heterologous | 1995 |
Fatal pulmonary toxicity following oral etoposide therapy.
Topics: Administration, Oral; Carcinoma, Small Cell; Etoposide; Fatal Outcome; Humans; Lung Neoplasms; Male; Middle Aged; Pulmonary Fibrosis | 1995 |
Ifosfamide, carboplatin and etoposide for good prognosis small cell lung cancer: are four courses inadequate? West of Scotland Lung Cancer Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Female; Humans; Ifosfamide; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Prognosis; Survival Analysis; Treatment Outcome | 1995 |
An etoposide-resistant lung cancer subline overexpresses the multidrug resistance-associated protein.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Carcinoma, Small Cell; DNA Topoisomerases, Type II; Drug Resistance; Drug Resistance, Multiple; Etoposide; Gene Expression; Humans; Lung Neoplasms; Male; Membrane Proteins; Middle Aged; Multidrug Resistance-Associated Proteins; Phenotype; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1995 |
[Chemotherapy for older cancer patients].
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Female; Floxuridine; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Lymphoma, Non-Hodgkin; Male; Neoplasms; Neoplasms, Multiple Primary; Palliative Care; Quality of Life | 1993 |
A limited sampling method for estimation of the etoposide area under the curve.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Lung Neoplasms; Male; Models, Biological; Regression Analysis | 1993 |
Is carboplatin and oral etoposide an effective and feasible regimen in patients with small cell lung cancer?
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Female; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Radiotherapy, Adjuvant; Thrombocytopenia | 1995 |
Extrapulmonary small cell carcinoma: a single-institution experience and review of the literature.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Etoposide; Female; Humans; Laryngeal Neoplasms; Male; Middle Aged; Prostatic Neoplasms; Remission Induction; Retrospective Studies; Urinary Bladder Neoplasms | 1994 |
Dose intensity of the CAVE regimen in small cell lung cancer correlates to response rate.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Retrospective Studies; Survival Analysis; Vincristine | 1994 |
[A case of small cell lung cancer with renal insufficiency effectively treated with oral etoposide administration].
Topics: Administration, Oral; Aged; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Female; Heart Failure; Humans; Lung Neoplasms; Remission Induction; Renal Insufficiency | 1995 |
Resistance-associated factors in human small-cell lung-carcinoma GLC4 sub-lines with increasing adriamycin resistance.
Topics: ATP-Binding Cassette Transporters; Base Sequence; Biological Transport; Carcinoma, Small Cell; Cell Division; Cell Line; Cell Membrane; Daunorubicin; DNA Primers; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance, Multiple; Etoposide; Gene Expression; Humans; Lung Neoplasms; Membrane Proteins; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Phosphorylation; Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Vincristine | 1995 |
Surgical treatment of small cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Prognosis; Retrospective Studies; Survival Rate; Vincristine | 1995 |
Postincubation with aclarubicin reverses topoisomerase II mediated DNA cleavage, strand breaks, and cytotoxicity induced by VP-16.
Topics: Aclarubicin; Animals; Carcinoma, Small Cell; DNA Damage; DNA, Neoplasm; Etoposide; Humans; Lung Neoplasms; Mice; Time Factors; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1994 |
SEQPWR and SEQOPR: computer programs for design of maximum information trials based on group sequential logrank tests.
Topics: Algorithms; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Clinical Trials, Phase III as Topic; Data Interpretation, Statistical; Etoposide; Feasibility Studies; Follow-Up Studies; Humans; Linear Models; Lung Neoplasms; Programming Languages; Research Design; Sensitivity and Specificity; Software; Survival Rate; Topotecan | 1995 |
[Response rate of small cell lung cancer treated with CE-CAP alternating chemotherapy].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged | 1994 |
Reversible myocardial ischaemia following vincristine containing chemotherapy.
Topics: Carcinoma, Small Cell; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Middle Aged; Myocardial Ischemia; Vincristine | 1994 |
Different topoisomerase II antitumor drugs direct similar specific long-range fragmentation of an amplified c-MYC gene locus in living cells and in high-salt-extracted nuclei.
Topics: Amsacrine; Antineoplastic Agents; Carcinoma, Small Cell; Cell Fractionation; Cell Line; Cell Nucleus; DNA Damage; DNA Topoisomerases, Type II; DNA, Neoplasm; Etoposide; Exons; Genes, myc; Humans; Lung Neoplasms; Restriction Mapping; Saline Solution, Hypertonic; Teniposide; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1995 |
[Small cell bronchial cancer in a 17-year-old young man].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lung; Lung Neoplasms; Lymph Node Excision; Lymphatic Metastasis; Male; Neoplasm Metastasis; Pneumonectomy | 1994 |
Sequential coexpression of the multidrug resistance genes MRP and mdr1 and their products in VP-16 (etoposide)-selected H69 small cell lung cancer cells.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Carcinoma, Small Cell; Cell Line; Drug Resistance, Multiple; Etoposide; Gene Expression; Humans; Immunoblotting; Immunohistochemistry; Lung Neoplasms; Multidrug Resistance-Associated Proteins; Polymerase Chain Reaction; Proteins; Tumor Cells, Cultured | 1995 |
Therapy for small cell lung cancer using carboplatin, ifosfamide, etoposide (without dose reduction), mid-cycle vincristine with thoracic and cranial irradiation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Prospective Studies; Treatment Outcome; Vincristine | 1994 |
[Therapeutic effect of carboplatin and etoposide combinative therapy on 123 lung cancer cases].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Etoposide; Humans; Leukopenia; Lung Neoplasms; Middle Aged; T-Lymphocyte Subsets | 1994 |
Response of a multidrug-resistant human small-cell lung cancer xenograft to chemotherapy.
Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Small Cell; Carrier Proteins; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Resistance; Etoposide; Female; Flow Cytometry; Humans; Lung Neoplasms; Male; Membrane Glycoproteins; Mice; Mice, Nude; Neoplasm Proteins; Neoplasm Transplantation; Time Factors; Verapamil | 1993 |
A metastatic neuroendocrine anaplastic small cell tumor in a patient with multiple endocrine neoplasia type 1 syndrome. Assessment of disease status and response to doxorubicin, cyclophosphamide, etoposide chemotherapy through scintigraphic imaging with 1
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Disease Progression; Doxorubicin; Etoposide; Fatal Outcome; Female; Humans; Indium Radioisotopes; Middle Aged; Multiple Endocrine Neoplasia Type 1; Radionuclide Imaging; Salvage Therapy; Somatostatin | 1994 |
Etoposide-induced cell cycle delay and arrest-dependent modulation of DNA topoisomerase II in small-cell lung cancer cells.
Topics: Bromodeoxyuridine; Carcinoma, Small Cell; Cell Cycle; DNA Damage; DNA Topoisomerases, Type II; Etoposide; Flow Cytometry; G1 Phase; Genes, p53; Humans; Kinetics; Lung Neoplasms; Mutation; S Phase; Tumor Cells, Cultured | 1994 |
Acute myelomonocytic leukemia after treatment with chronic oral etoposide: are MLL and LTG9 genes targets for etoposide?
Topics: Administration, Oral; Aged; Base Sequence; Carcinoma, Small Cell; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 9; Drug Administration Schedule; Etoposide; Genes; Humans; Leukemia, Myelomonocytic, Acute; Lung Neoplasms; Male; Molecular Sequence Data; Neoplasms, Second Primary; Polymerase Chain Reaction; Translocation, Genetic | 1994 |
In vitro and in vivo effects of cisplatin and etoposide in combination on small cell lung cancer cell lines.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Lung Neoplasms; Male; Mice; Mice, Nude; Neoplasm Transplantation; Transplantation, Heterologous; Tumor Cells, Cultured | 1994 |
Reduced levels of topoisomerase II alpha and II beta in a multidrug-resistant lung-cancer cell line.
Topics: Blotting, Northern; Carcinoma, Small Cell; DNA Probes; DNA Topoisomerases, Type II; Drug Resistance; Etoposide; Humans; Lung Neoplasms; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured | 1994 |
[Immunohistochemical study and treatment result of small cell lung carcinoma using combination chemotherapy].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chromogranin A; Chromogranins; Combined Modality Therapy; Cyclophosphamide; Etoposide; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Phosphopyruvate Hydratase; Prednisone; Prognosis; Remission Induction; Vincristine | 1994 |
Multifocal osteonecrosis following chemotherapy and short-term corticosteroid therapy in a patient with small-cell bronchogenic carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone and Bones; Carboplatin; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Dexamethasone; Etoposide; Humans; Lung Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Osteonecrosis; Radionuclide Imaging | 1994 |
[Successful treatment of refractory extensive small cell lung cancer by oral etoposide].
Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged | 1994 |
Enhanced expression of HLA-A,B,C and inducibility of TAP-1, TAP-2, and HLA-A,B,C by interferon-gamma in a multidrug-resistant small cell lung cancer line.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 2; ATP Binding Cassette Transporter, Subfamily B, Member 3; ATP-Binding Cassette Transporters; Base Sequence; Breast Neoplasms; Carcinoma, Small Cell; Carrier Proteins; Cytotoxicity, Immunologic; DNA Primers; Drug Resistance; Etoposide; Female; Gene Expression; HLA Antigens; Humans; Interferon-gamma; Killer Cells, Lymphokine-Activated; Lung Neoplasms; Molecular Sequence Data; Ovarian Neoplasms; Recombinant Proteins; Tumor Cells, Cultured | 1994 |
Effect of intravenous immunoglobulin in Lambert-Eaton myasthenic syndrome with small-cell lung cancer: correlation with the titer of anti-voltage-gated calcium channel antibody.
Topics: Action Potentials; Aged; Antineoplastic Combined Chemotherapy Protocols; Calcium Channels; Carcinoma, Small Cell; Cyclophosphamide; Etoposide; Humans; Immunoglobulin G; Immunoglobulins, Intravenous; Lambert-Eaton Myasthenic Syndrome; Lung Neoplasms; Male; Muscles; Plasmapheresis | 1994 |
Consolidative thoracic radiotherapy and prophylactic cranial irradiation in limited disease small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Doxorubicin; Epirubicin; Etoposide; Lomustine; Lung Neoplasms; Methotrexate; Remission Induction; Survival Analysis; Thorax; Treatment Outcome; Vincristine | 1993 |
Teniposide for meningeal carcinomatosis of small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carboplatin; Carcinoma, Small Cell; Cyclophosphamide; Dexamethasone; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Immunologic Factors; Injections, Spinal; Interferon-gamma; Lung Neoplasms; Meningeal Neoplasms; Middle Aged; Morphine; Teniposide; Vincristine | 1993 |
The prognostic significance of bone marrow metastases in small cell lung cancer patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Prognosis; Proportional Hazards Models; Survival Analysis | 1993 |
A Bayesian analysis of institutional effects in a multicenter cancer clinical trial.
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Bayes Theorem; Biometry; Carcinoma, Small Cell; Cyclophosphamide; Data Interpretation, Statistical; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Methotrexate; Multicenter Studies as Topic; Probability; Proportional Hazards Models; Randomized Controlled Trials as Topic; Vincristine | 1994 |
Considerations on radiotherapy dose intensity for limited small cell lung cancer.
Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Clinical Trials as Topic; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Etoposide; Humans; Lung Neoplasms; Platinum; Radiotherapy Dosage; Time Factors | 1994 |
Differential cytotoxicity of 19 anticancer agents in wild type and etoposide resistant small cell lung cancer cell lines.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Small Cell; Daunorubicin; DNA Topoisomerases, Type II; Drug Resistance; Drug Screening Assays, Antitumor; Etoposide; Humans; Lung Neoplasms; Membrane Glycoproteins; Tumor Cells, Cultured | 1993 |
Altered topoisomerase II alpha in a drug-resistant small cell lung cancer cell line selected in VP-16.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Carcinoma, Small Cell; Carrier Proteins; Cell Line; Chromosome Banding; DNA Topoisomerases, Type II; Drug Resistance; Electrophoresis, Polyacrylamide Gel; Etoposide; Gene Deletion; Genetic Markers; Humans; Isoenzymes; Karyotyping; Lung Neoplasms; Membrane Glycoproteins; RNA, Messenger; Tumor Cells, Cultured | 1993 |
Carboplatin, epirubicin, and VP-16 chemotherapy in the treatment of small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Epirubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Remission Induction; Survival Rate | 1994 |
Targeting the cytotoxicity of topoisomerase II-directed epipodophyllotoxins to tumor cells in acidic environments.
Topics: Amsacrine; Animals; Carcinoma, Small Cell; Chloroquine; DNA Damage; DNA Topoisomerases, Type II; DNA, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Etoposide; Humans; Hydrogen-Ion Concentration; Leukemia L1210; Lung Neoplasms; Mice; Tumor Cells, Cultured | 1994 |
Etoposide-related acral erythema.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Erythema; Etoposide; Hand; Humans; Lung Neoplasms; Male; Middle Aged; Recurrence | 1994 |
VP-16, ifosfamide and cisplatin (VIP) for extensive small cell lung cancer.
Topics: Adult; Aged; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Treatment Outcome | 1994 |
[Neoadjuvant chemotherapy effective for small cell lung cancer in a nephrectomized patient].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Renal Cell; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Male; Neoplasms, Second Primary; Nephrectomy | 1993 |
Clinical significance of DNA measurements in small cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bronchi; Carcinoma, Small Cell; Cisplatin; DNA, Neoplasm; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Ploidies; Probability; Prognosis; Remission Induction; Sensitivity and Specificity | 1993 |
Clinical trials referral resource. Small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Etoposide; Humans; Lung Neoplasms; Tamoxifen | 1993 |
A simulated sequential analysis based on data from two MRC trials.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Data Interpretation, Statistical; Etoposide; Humans; Lung Neoplasms; Methotrexate; Proportional Hazards Models; Radiotherapy, High-Energy; Randomized Controlled Trials as Topic; Regression Analysis; Research Design; Survival Analysis; Survival Rate; Vincristine | 1993 |
Treatment of small cell lung cancer in the elderly.
Topics: Activities of Daily Living; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Comorbidity; Cyclophosphamide; Doxorubicin; Effect Modifier, Epidemiologic; Etoposide; Female; Geriatric Assessment; Humans; Lung Neoplasms; Male; Neoplasm Staging; Prognosis; Proportional Hazards Models; Retrospective Studies; Selection Bias; Survival Rate; Treatment Outcome; Vincristine | 1994 |
Small cell carcinoma of the esophagus with an esophago-mediastinal fistula successfully treated by chemoradiation therapy and intubation: a case report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cobalt Radioisotopes; Combined Modality Therapy; Esophageal Fistula; Esophageal Neoplasms; Etoposide; Fistula; Fluorouracil; Humans; Intubation; Lymphatic Metastasis; Male; Mediastinal Diseases; Middle Aged; Radiotherapy Dosage | 1993 |
Apoptosis induced by etoposide in small-cell lung cancer cell lines.
Topics: Apoptosis; Carcinoma, Small Cell; DNA, Neoplasm; Endonucleases; Etoposide; Humans; Lung Neoplasms; Tumor Cells, Cultured | 1994 |
[A case of metastatic cancer of the stomach from small cell carcinoma of the lung].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Male; Stomach Neoplasms; Vincristine | 1993 |
Patient compliance with prolonged low-dose oral etoposide for small cell lung cancer.
Topics: Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Patient Compliance | 1993 |
Influence of platelet-derived microparticles on coagulation in a lung cancer patient receiving chemotherapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Coagulation; Blood Platelets; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Male; Vincristine | 1993 |
[In vitro comparison of podophyllotoxin analogues; etoposide, teniposide and NK 611 using human lung cancer cell lines].
Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cell Division; Drug Resistance; Drug Screening Assays, Antitumor; Etoposide; Humans; Lung Neoplasms; Podophyllotoxin; Teniposide; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1993 |
Management of small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Etoposide; Humans; Ifosfamide; Lung Neoplasms; Neoplasm Staging; Paraneoplastic Syndromes; Survival Rate | 1993 |
High dose-intensity chemotherapy, with accelerated cyclophosphamide-doxorubicin-etoposide and granulocyte-macrophage colony stimulating factor, in the treatment of small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Feasibility Studies; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Thrombocytopenia; Time Factors | 1993 |
An unusual case of haematuria.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Hematuria; Humans; Ifosfamide; Male; Mesna; Quadriplegia; Urinary Bladder Neoplasms | 1993 |
[Cytotoxic effect of topoisomerase II inhibitors against adriamycin- and etoposide-resistant small cell lung cancer sublines].
Topics: Carcinoma, Small Cell; Doxorubicin; Drug Resistance; Etoposide; Humans; Lung Neoplasms; Polymerase Chain Reaction; RNA, Messenger; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1993 |
Prolonged, alternating chemotherapy for extensive small cell lung cancer. A Southwest oncology Group study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Remission Induction; Vincristine | 1993 |
Unusual presentation and course of Cushing's syndrome due to ectopic ACTH secretion by a bronchial carcinoma.
Topics: ACTH Syndrome, Ectopic; Adult; Carcinoma, Small Cell; Cisplatin; Cushing Syndrome; Dexamethasone; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms | 1993 |
[Assessment of antitumor activity rhizoxin for human lung cancer cell lines: a potent new drug for drug-resistant lung cancer].
Topics: Antibiotics, Antineoplastic; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Drug Resistance; Drug Screening Assays, Antitumor; Etoposide; Humans; Lactones; Lung Neoplasms; Macrolides; Tumor Cells, Cultured | 1993 |
[Antigen phenotype of lung cancer and its relation to chemo-radiosensitivity].
Topics: Antibodies, Monoclonal; Antigens, Neoplasm; Antineoplastic Agents; Carcinoma, Small Cell; Cell Survival; Etoposide; Humans; Immunohistochemistry; Immunophenotyping; Lung Neoplasms; Radiotherapy Dosage; Tumor Cells, Cultured | 1993 |
Prolonged oral etoposide in small cell lung cancer.
Topics: Administration, Oral; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Humans; Lung Neoplasms | 1993 |
Chronic oral etoposide in small-cell lung cancer: clinical and pharmacokinetic results.
Topics: Administration, Oral; Aged; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neutropenia | 1993 |
Etoposide and secondary haematological malignancies: coincidence or causality?
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Chromosome Aberrations; Chromosome Disorders; Etoposide; Female; Hematologic Diseases; Hodgkin Disease; Humans; Karyotyping; Lung Neoplasms; Male; Middle Aged; Neoplasms, Second Primary | 1993 |
Prospective evaluation of the effect on initial brain metastases from small cell lung cancer of platinum-etoposide based induction chemotherapy followed by an alternating multidrug regimen.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Prospective Studies; Remission Induction; Survival Analysis; Tomography, X-Ray | 1993 |
[Antiemetic efficacy of granisetron in patients receiving 5-day continuous infusion of cisplatin].
Topics: Adenocarcinoma; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Etoposide; Female; Granisetron; Humans; Indazoles; Infusions, Intra-Arterial; Lung Neoplasms; Male; Middle Aged; Nausea; Vindesine; Vomiting | 1993 |
Surgical treatment of small cell carcinoma of the lung: advantage of preoperative chemotherapy.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasm Staging; Prednisone; Preoperative Care; Prognosis; Retrospective Studies; Vincristine | 1995 |
Antitumor activity of treosulfan in human lung carcinomas.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Busulfan; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Ifosfamide; Lung Neoplasms; Male; Mice; Mice, Nude; Mitomycin; Neoplasm Transplantation; Time Factors | 1996 |
Adding a reverser (verapamil) to combined chemotherapy overrides resistance in small cell lung cancer xenografts.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Transplantation, Heterologous; Verapamil | 1995 |
[Leukoencephalopathy in a patient being treated for small cell lung cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Cisplatin; Cranial Irradiation; Etoposide; Humans; Leukoencephalopathy, Progressive Multifocal; Lung Neoplasms; Male; Middle Aged; Radiotherapy | 1995 |
Serum cytokine level fluctuations in chemotherapy-induced myelosuppression.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bone Marrow; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Fluorouracil; Granulocyte Colony-Stimulating Factor; Humans; Interleukin-1; Interleukin-3; Interleukin-6; Lung Neoplasms; Male; Middle Aged; Neoplasms, Unknown Primary; Stem Cell Factor | 1996 |
Influence of age on the treatment of limited-stage small-cell lung cancer.
Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Child; Child, Preschool; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Infant; Lung Neoplasms; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Retrospective Studies; Survival Analysis; Vincristine | 1996 |
Extensive stage small cell lung cancer: determining suitability for outpatient management of febrile neutropenia.
Topics: Adrenal Gland Neoplasms; Ambulatory Care; Anti-Bacterial Agents; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Decision Making; Etoposide; Female; Fever; Hospitalization; Humans; Liver Neoplasms; Lung Neoplasms; Middle Aged; Neutropenia | 1996 |
Mechanisms of resistance of human small cell lung cancer lines selected in VP-16 and cisplatin.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cadmium; Cadmium Chloride; Carcinoma, Small Cell; Cell Line; Chlorides; Cisplatin; Cross Reactions; DNA; DNA Topoisomerases, Type II; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Humans; Lung Neoplasms; Metallothionein; Platinum Compounds; Podophyllotoxin; Teniposide; Tumor Cells, Cultured; Vinca Alkaloids | 1996 |
MRP is frequently expressed in human lung-cancer cell lines, in non-small-cell lung cancer and in normal lungs.
Topics: Antineoplastic Agents; ATP-Binding Cassette Transporters; Biological Transport; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; DNA, Complementary; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Fluoresceins; Gene Expression Regulation, Neoplastic; Humans; Lung; Lung Neoplasms; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Tumor Cells, Cultured | 1996 |
[A case report of small cell carcinoma of the esophagus with remarkable response to neoadjuvant chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Drug Administration Schedule; Esophageal Neoplasms; Esophagectomy; Etoposide; Fluorouracil; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged | 1996 |
Full chemotherapy in elderly patients with small cell bronchial carcinoma.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bronchial Neoplasms; Carcinoma, Small Cell; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Etoposide; Female; Humans; Lomustine; Male; Methotrexate; Middle Aged; Multivariate Analysis; Radiotherapy, Adjuvant; Sepsis; Survival Rate; Vincristine | 1996 |
Vasospastic angina after chemotherapy by with carboplatin and etoposide in a patient with lung cancer.
Topics: Aged; Angina Pectoris; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Coronary Vasospasm; Etoposide; Humans; Lung Neoplasms; Male | 1996 |
Oral etoposide and palliative treatment for small-cell lung cancer.
Topics: Administration, Oral; Aged; Antineoplastic Agents; Carcinoma, Small Cell; Etoposide; Humans; Lung Neoplasms; Palliative Care; Survival Rate | 1996 |
Higher in vivo protein binding of etoposide in children compared with adult cancer patients.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Carcinoma, Small Cell; Child; Child, Preschool; Etoposide; Female; Histiocytic Sarcoma; Humans; Infant; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma; Male; Middle Aged; Multiple Myeloma; Oligodendroglioma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Binding; Reference Values; Serum Albumin | 1996 |
Resolution of superior vena cava obstruction in small cell lung cancer patients treated with chemotherapy.
Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Neoplastic Cells, Circulating; Remission Induction; Survival Rate; Time Factors; Vena Cava, Superior; Vincristine | 1995 |
Effect of v-rasH on sensitivity of NCI-H82 human small cell lung cancer cells to cisplatin, etoposide, and camptothecin.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Small Cell; Cell Survival; Cisplatin; Drug Resistance; Etoposide; Genes, ras; Humans; Lung Neoplasms; Metallothionein; Phenotype; RNA, Messenger; RNA, Transfer; Sulfhydryl Compounds; Transfection; Tumor Cells, Cultured | 1995 |
Treatment of patients with small-cell lung cancer refractory to etoposide and cisplatin with the topoisomerase I poison topotecan.
Topics: Adult; Aged; Aged, 80 and over; Agranulocytosis; Antineoplastic Agents; Camptothecin; Carcinoma, Small Cell; Cisplatin; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Thrombocytopenia; Topotecan | 1996 |
Treatment of small cell lung cancer: a single institutional experience.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Survival Rate; Vincristine | 1996 |
Reduced expression of DNA topoisomerase II confers resistance to etoposide (VP-16) in small cell lung cancer cell lines established from a refractory tumor of a patient and by in vitro selection.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance, Neoplasm; Enzyme Induction; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Neoplasm Proteins; Piperazines; Selection, Genetic; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Vincristine | 1996 |
Characterization of the protein kinase C signal transduction pathway in cisplatin-sensitive and -resistant human small cell lung carcinoma cells.
Topics: Antineoplastic Agents; Bleomycin; Bryostatins; Carcinoma; Carcinoma, Small Cell; Cisplatin; Drug Resistance, Neoplasm; Enzyme Activation; Etoposide; Female; Head and Neck Neoplasms; Herpes Simplex Virus Protein Vmw65; Humans; Lactones; Lung Neoplasms; Macrolides; Ovarian Neoplasms; Paclitaxel; Phorbol 12,13-Dibutyrate; Protein Kinase C; Signal Transduction; Tumor Cells, Cultured | 1996 |
Comparison of carboplatin/etoposide/vincristine with cisplatin/etoposide as combination chemotherapy for small cell lung cancer.
Topics: Antineoplastic Agents; Carboplatin; Carcinoma, Small Cell; Drug Therapy, Combination; Etoposide; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Vincristine | 1995 |
Dose-intensive weekly chemotherapy for treatment of relapsed small-cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Middle Aged; Remission Induction; Vincristine | 1997 |
Topoisomerase II alpha content and topoisomerase II catalytic activity cannot explain drug sensitivities to topoisomerase II inhibitors in lung cancer cell lines.
Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cell; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Neoplasm; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Humans; Isoenzymes; Lung Neoplasms; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1997 |
A pharmacoeconomic evaluation of cisplatin in combination with either etoposide or etoposide phosphate in small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Costs and Cost Analysis; Economics, Pharmaceutical; Etoposide; Humans; Lung Neoplasms; Models, Economic; Organophosphorus Compounds | 1996 |
[A case of small cell lung carcinoma associated with pneumoconiosis who responded well to the over twenty chemotherapy treatments, resulting in prolonged survival].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Humans; Lung Neoplasms; Male; Middle Aged; Pneumoconiosis; Survivors; Vincristine | 1997 |
Annamycin circumvents resistance mediated by the multidrug resistance-associated protein (MRP) in breast MCF-7 and small-cell lung UMCC-1 cancer cell lines selected for resistance to etoposide.
Topics: Antibiotics, Antineoplastic; ATP-Binding Cassette Transporters; Blotting, Western; Breast Neoplasms; Carcinoma, Small Cell; Cell Survival; DNA Damage; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Fluorescent Antibody Technique, Indirect; Humans; Immunohistochemistry; Multidrug Resistance-Associated Proteins; Tumor Cells, Cultured | 1997 |
[Etoposide-induced pneumonitis].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Etoposide; Humans; Lung Neoplasms; Male; Pneumonia | 1997 |
Evaluation of synergism by a novel three-dimensional model for the combined action of cisplatin and etoposide on the growth of a human small-cell lung-cancer cell line, SBC-3.
Topics: Antineoplastic Agents; Carcinoma, Small Cell; Cell Division; Cisplatin; Drug Synergism; Etoposide; Humans; Lung Neoplasms; Models, Theoretical; Probability; Tumor Cells, Cultured | 1997 |
Tolerability and efficacy of GM-CSF [Leucomax] in patients with small cell lung cancer treated with intensive chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chi-Square Distribution; Cisplatin; Drug Resistance, Neoplasm; Etoposide; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Middle Aged; Neutropenia; Survival Analysis | 1996 |
Two COOH-terminal truncated cytoplasmic forms of topoisomerase II alpha in a VP-16-selected lung cancer cell line result from partial gene deletion and alternative splicing.
Topics: Amino Acid Sequence; Base Composition; Base Sequence; Blotting, Northern; Carcinoma, Small Cell; Cloning, Molecular; Cytoplasm; DNA Topoisomerases, Type II; Etoposide; Gene Deletion; Humans; Lung Neoplasms; Molecular Sequence Data; Molecular Weight; Polymerase Chain Reaction; Restriction Mapping; RNA-Directed DNA Polymerase; RNA, Messenger; Sequence Analysis, DNA; Tumor Cells, Cultured | 1997 |
Expression of the multidrug resistance-associated protein gene in refractory lymphoma: quantitation by a validated polymerase chain reaction assay.
Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biopsy; Breast Neoplasms; Carcinoma, Small Cell; Cyclophosphamide; DNA, Neoplasm; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Lung Neoplasms; Lymphoma; Neoplasm Proteins; Polymerase Chain Reaction; Prednisone; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured; Verapamil; Vincristine | 1997 |
[Investigation of chemotherapy combined with peripheral blood stem cell transplantation (PBSCT) both in elderly and in recurred patients with small cell lung cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Drug Administration Schedule; Etoposide; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Lung Neoplasms; Male; Middle Aged; Platelet Count; Recombinant Proteins | 1997 |
[Case of ectopic ACTH-producing small cell carcinoma of the lung: a reduction in tumor size after chemotherapy in spite of a marked rise in the plasma ACTH level].
Topics: Adrenocorticotropic Hormone; Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Hormones, Ectopic; Humans; Lung Neoplasms | 1997 |
[Small cell lung cancer with acute monocytic leukemia after combined chemotherapy including etoposide].
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Etoposide; Female; Humans; Leukemia, Monocytic, Acute; Lung Neoplasms; Middle Aged; Neoplasms, Second Primary | 1997 |
Multidrug-resistant gene expression in small-cell lung cancer.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Northern; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Female; Gene Expression Regulation, Neoplastic; Genes, MDR; Humans; Immunoblotting; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Polymerase Chain Reaction; Survival Analysis; Survival Rate; Transcription, Genetic; Treatment Failure; Tumor Cells, Cultured; Vincristine | 1997 |
Advanced-stage small cell carcinoma of the ovary in pregnancy: long-term survival after surgical debulking and multiagent chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Etoposide; Female; Humans; Neoplasm Staging; Ovarian Neoplasms; Pregnancy; Pregnancy Complications, Neoplastic; Vinblastine | 1997 |
New drugs for small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Deoxycytidine; Doxorubicin; Etoposide; Gemcitabine; Humans; Irinotecan; Lung Neoplasms; Paclitaxel; Vincristine | 1997 |
Mutation frequency and spectrum in lymphocytes of small cell lung cancer patients receiving etoposide chemotherapy.
Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Small Cell; Clone Cells; DNA Damage; DNA, Neoplasm; Enzyme Inhibitors; Etoposide; Female; Humans; Hypoxanthine Phosphoribosyltransferase; Lung Neoplasms; Male; Mutagenesis; Point Mutation; Polymerase Chain Reaction; T-Lymphocytes; Topoisomerase II Inhibitors | 1997 |
Limited-stage small cell lung cancer: a case report.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bronchoscopy; Carboplatin; Carcinoma, Small Cell; Etoposide; Humans; Lung Neoplasms; Male; Neoplasm Staging; Radiotherapy, Adjuvant | 1997 |
Experience with ifosfamide and etoposide combination chemotherapy in extensive-disease small-cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Etoposide; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged | 1997 |
Loss of amino acids 1490Lys-Ser-Lys1492 in the COOH-terminal region of topoisomerase IIalpha in human small cell lung cancer cells selected for resistance to etoposide results in an extranuclear enzyme localization.
Topics: Amino Acid Sequence; Amino Acid Substitution; Antigens, Neoplasm; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Carcinoma, Small Cell; Cell Nucleus; Consensus Sequence; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Humans; Isoenzymes; Lung Neoplasms; Lysine; Molecular Sequence Data; Molecular Weight; Multidrug Resistance-Associated Proteins; Peptide Fragments; Point Mutation; Polymerase Chain Reaction; RNA, Messenger; Sequence Deletion; Serine; Tumor Cells, Cultured | 1997 |
[A case report of coronary artery bypass graft surgery and subsequent chemotherapy for the patient with unstable angina and small cell lung cancer].
Topics: Aged; Angina, Unstable; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Coronary Artery Bypass; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Vincristine | 1994 |
Technetium-99m-MIBI uptake in small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Case-Control Studies; Cisplatin; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Radiopharmaceuticals; Technetium Tc 99m Sestamibi; Tomography, Emission-Computed, Single-Photon | 1998 |
Metastatic small-cell carcinoma of rectum responding dramatically to combination chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Male; Rectal Neoplasms; Remission Induction | 1998 |
Multidrug resistance modulation in rhabdomyosarcoma and neuroblastoma cell lines.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Small Cell; Cell Survival; Cisplatin; Cyclophosphamide; Cyclosporine; Doxorubicin; Drug Resistance, Multiple; Etoposide; Humans; Kinetics; Lung Neoplasms; Methotrexate; Neuroblastoma; Rhabdomyosarcoma; Time Factors; Tumor Cells, Cultured; Verapamil; Vincristine | 1998 |
Induction of broad drug resistance in small cell lung cancer cells and its reversal by paclitaxel.
Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bacterial Proteins; Carcinoma, Small Cell; Chlorambucil; Cisplatin; Drug Interactions; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Humans; Lung Neoplasms; Paclitaxel; RNA, Messenger; Serine Endopeptidases; Tumor Cells, Cultured; Vinblastine | 1998 |
Management of chemotherapy-related anaemia with low-dose recombinant human erythropoietin in patients with small cell lung cancer.
Topics: Anemia; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Erythropoietin; Etoposide; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Recombinant Proteins; Retrospective Studies | 1997 |
[Evaluation of polychemotherapy of small cell lung carcinoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Retrospective Studies; Vincristine | 1995 |
Monitoring of p53 autoantibodies in lung cancer during therapy: relationship to response to treatment.
Topics: Antibody Formation; Antibody Specificity; Antineoplastic Combined Chemotherapy Protocols; Autoantibodies; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Enzyme-Linked Immunosorbent Assay; Etoposide; Genes, p53; Humans; Lung Neoplasms; Monitoring, Immunologic; Neoplasm Staging; Prognosis; Radiotherapy; Survival Rate; Tumor Suppressor Protein p53 | 1998 |
[Endoscopic findings of esophagitis in concurrent chemo-radiotherapy for lung cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Esophagitis; Esophagoscopy; Etoposide; Humans; Lung Neoplasms; Middle Aged; Mitomycin; Radiation Injuries; Radiotherapy; Vindesine | 1998 |
[A case of binocular blindness in small cell lung cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Blindness; Carcinoma, Small Cell; Cyclophosphamide; Epirubicin; Etoposide; Fatal Outcome; Humans; Lung Neoplasms; Male; Paraneoplastic Syndromes | 1998 |
Predictive factors of tumor response and prognostic factors of survival during lung cancer chemotherapy.
Topics: Analysis of Variance; Antibiotics, Antineoplastic; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Etoposide; Humans; Keratin-19; Keratins; L-Lactate Dehydrogenase; Lung Neoplasms; Phosphopyruvate Hydratase; Prognosis; Regression Analysis; Tissue Polypeptide Antigen | 1998 |
Enhanced myelotoxicity due to granulocyte colony-stimulating factor administration until 48 hours before the next chemotherapy course in patients with small-cell lung carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carboplatin; Carcinoma, Small Cell; Cyclophosphamide; Epirubicin; Etoposide; Granulocyte Colony-Stimulating Factor; Humans; Ifosfamide; Lung Neoplasms; Mesna; Prospective Studies; Recombinant Proteins; Vincristine | 1998 |
Multidrug resistance genes (MRP) and MDR1 expression in small cell lung cancer xenografts: relationship with response to chemotherapy.
Topics: Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Genes, MDR; Humans; Lung Neoplasms; Male; Mice; Mice, Nude; Middle Aged; Neoplasm Transplantation; RNA, Messenger; Transplantation, Heterologous | 1998 |
Abbreviated treatment for elderly, infirm, or noncompliant patients with limited-stage small-cell lung cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Survival Rate; Treatment Refusal; Vincristine | 1998 |
Combination of irinotecan and etoposide for treatment of refractory or relapsed small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Etoposide; Female; Humans; Irinotecan; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Survival Analysis | 1998 |
Synergistic cytotoxicity of bcl-2 antisense oligodeoxynucleotides and etoposide, doxorubicin and cisplatin on small-cell lung cancer cell lines.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Drug Synergism; Etoposide; Humans; Lung Neoplasms; Oligonucleotides, Antisense; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured | 1998 |
Clinical pharmacology of chronic oral etoposide in patients with small cell and non-small cell lung cancer.
Topics: Administration, Oral; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Agents, Phytogenic; Biological Availability; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neutropenia; Thrombocytopenia | 1995 |
Decreased metastasis and improved survival with early thoracic radiotherapy and prophylactic cranial irradiation in combined-modality treatment of limited-stage small cell lung cancer.
Topics: Aged; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Combined Modality Therapy; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Multivariate Analysis; Platinum Compounds; Predictive Value of Tests; Survival Analysis; Treatment Outcome | 1998 |
Bcl-2 expression correlates with apoptosis induction but not loss of clonogenic survival in small cell lung cancer cell lines treated with etoposide.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Small Cell; Cell Survival; Culture Media; Cystine; Etoposide; Gene Expression; Genes, bcl-2; Humans; Lung Neoplasms; Methionine; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured | 1998 |
Long term results of surgery and chemotherapy in small cell lung cancer.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Cranial Irradiation; Cyclophosphamide; Doxorubicin; Epirubicin; Etoposide; Female; Follow-Up Studies; Humans; Longitudinal Studies; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Pneumonectomy; Postoperative Complications; Prospective Studies; Radiotherapy, Adjuvant; Survival Rate; Vincristine | 1998 |
Chemotherapy for small cell lung carcinoma: the Greenlane Hospital experience 1993-1995.
Topics: Actuarial Analysis; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; New Zealand; Retrospective Studies; Survival Analysis; Treatment Outcome; Vincristine | 1998 |
Pharmacodynamic profile of prolonged etoposide administration in patients with small cell lung cancer and non-Hodgkin's lymphoma.
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Carcinoma, Small Cell; Drug Evaluation; Drug Monitoring; Etoposide; Humans; Lung Neoplasms; Lymphoma, Non-Hodgkin; Middle Aged | 1999 |
Activity of fenretinide plus chemotherapeutic agents in small-cell lung cancer cell lines.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cell Division; Cisplatin; Dose-Response Relationship, Drug; Drug Interactions; Etoposide; Fenretinide; Humans; Lung Neoplasms; Paclitaxel; Tumor Cells, Cultured | 1999 |
[A case of small cell carcinoma of the stomach with multiple liver and lung metastases successfully treated by combined chemotherapy with cisplatin and etoposide].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Etoposide; Gastrectomy; Humans; Liver Neoplasms; Lung Neoplasms; Lymph Node Excision; Male; Middle Aged; Splenectomy; Stomach Neoplasms | 1999 |
The influence of age on the delivery, tolerance, and efficacy of thoracic irradiation in the combined modality treatment of limited stage small cell lung cancer.
Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Patient Compliance; Radiation Pneumonitis; Radiotherapy Dosage; Randomized Controlled Trials as Topic; Retrospective Studies; Vincristine | 1999 |
Monocyte chemoattractant protein-1 gene modification of multidrug-resistant human lung cancer enhances antimetastatic effect of therapy with anti-P-glycoprotein antibody in SCID mice.
Topics: Animals; Antibodies, Monoclonal; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Small Cell; Chemokine CCL2; Clone Cells; Drug Resistance, Multiple; Etoposide; Humans; Immunotherapy; Lung Neoplasms; Mice; Mice, SCID; Neoplasm Metastasis; Organ Specificity; Recombinant Proteins; Transfection; Tumor Cells, Cultured | 1999 |
Hepatic artery administration of paclitaxel.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cimetidine; Combined Modality Therapy; Dexamethasone; Diphenhydramine; Etoposide; Hepatic Artery; Humans; Injections, Intra-Arterial; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Premedication | 1999 |
[Association of celiac disease and esophageal small cell carcinoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Celiac Disease; Cisplatin; Clinical Protocols; Esophageal Neoplasms; Etoposide; Humans; Male; Middle Aged; Remission Induction | 1999 |
Cost comparison between PAV and ICE treatment with peripheral blood progenitor cells (PBPC) reinfusion in small-cell lung cancer (SCLC)
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Etoposide; Health Care Costs; Hematopoietic Stem Cell Transplantation; Humans; Ifosfamide; Lung Neoplasms; Middle Aged | 1999 |
[Nedaplatin and etoposide combination chemotherapy in a patient with small cell carcinoma undergoing hemodialysis].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Humans; Kidney Failure, Chronic; Lung Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Remission Induction; Renal Dialysis | 1999 |
[Successful combination chemotherapy for a case of small cell carcinoma of the rectum with multiple liver metastasis].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chemoembolization, Therapeutic; Cisplatin; Doxorubicin; Etoposide; Hepatic Artery; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Iodized Oil; Liver Neoplasms; Male; Rectal Neoplasms | 1999 |
Potential cost savings of oral versus intravenous etoposide in the treatment of small cell lung cancer.
Topics: Administration, Oral; Carcinoma, Small Cell; Cisplatin; Cost Savings; Cost-Benefit Analysis; Etoposide; Health Care Costs; Humans; Infusions, Intravenous; Lung Neoplasms | 1992 |
Markov model and markers of small cell lung cancer: assessing the influence of reversible serum NSE, CYFRA 21-1 and TPS levels on prognosis.
Topics: Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Epirubicin; Etoposide; Humans; Keratin-19; Keratins; Lung Neoplasms; Markov Chains; Prognosis; Proportional Hazards Models; Prospective Studies; Tissue Polypeptide Antigen | 1999 |
Effect of vesnarinone in combination with anti-cancer drugs on lung cancer cell lines.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cell Division; Cisplatin; Coloring Agents; Deoxycytidine; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Flow Cytometry; Gemcitabine; Humans; Lung Neoplasms; Pyrazines; Quinolines; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1999 |
Enhanced sensitivity of small cell lung cancer cell lines to cisplatin and etoposide after infection with adeno-associated virus type 2.
Topics: Adenovirus Infections, Human; Animals; Antineoplastic Agents; Blotting, Southern; Carcinoma, Small Cell; Cell Division; Cisplatin; Dependovirus; Etoposide; Female; HeLa Cells; Humans; Lung Neoplasms; Mice; Mice, Nude; Tumor Cells, Cultured | 1999 |
Etoposide phosphate: new preparation. Makes outpatient therapy easier.
Topics: Antineoplastic Agents; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Drug Evaluation; Etoposide; France; Humans; Lung Neoplasms; Organophosphorus Compounds | 1998 |
Pharmacokinetics of etoposide after intrathoracic instillation to lung cancer patients with pleural effusion.
Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Phytogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Chromatography, High Pressure Liquid; Etoposide; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Pleural Effusion, Malignant | 1999 |
Severe muscle weakness due to hypokalemia as a manifestation of small-cell carcinoma.
Topics: ACTH Syndrome, Ectopic; Antineoplastic Agents; Carboplatin; Carcinoma, Small Cell; Etoposide; Humans; Hypokalemia; Lung Neoplasms; Male; Middle Aged; Muscle Weakness | 1999 |
Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo.
Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Bradykinin; Carcinoma, Small Cell; Caspase 3; Caspase Inhibitors; Caspases; Cell Adhesion; Cell Division; Collagen; Cyclophosphamide; Doxorubicin; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Extracellular Matrix Proteins; Fibronectins; Galanin; Humans; Integrin beta1; Laminin; Lung Neoplasms; Protein-Tyrosine Kinases; Tenascin; Tumor Cells, Cultured; Tyrphostins | 1999 |
Small cell carcinoma of the cervix complicated by pregnancy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Diagnosis, Differential; Etoposide; Female; Humans; Pregnancy; Pregnancy Complications, Neoplastic; Remission Induction; Uterine Cervical Neoplasms | 1999 |
[Accelerated hyperfractionated compared with conventional radiotherapy in limited small-cell lung carcinoma, with concurrent chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Dose Fractionation, Radiation; Etoposide; Humans; Lung Neoplasms; Radiotherapy; Radiotherapy Dosage | 1999 |
Vasospastic angina likely related to cisplatin-containing chemotherapy and thoracic irradiation for lung cancer.
Topics: Adenocarcinoma; Aged; Angina Pectoris, Variant; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Electrocardiography; Etoposide; Heart; Humans; Lung Neoplasms; Male; Middle Aged; Myocardial Ischemia; Neoplasm Staging; Radiation Injuries; Radiotherapy; Vindesine | 1999 |
Neuron-specific enolase, thymidine kinase, and tissue polypeptide-specific antigen in diagnosis and response to chemotherapy of small-cell lung cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Female; Humans; Immunoradiometric Assay; Lung Neoplasms; Male; Middle Aged; Phosphopyruvate Hydratase; Prospective Studies; Thymidine Kinase; Tissue Polypeptide Antigen; Treatment Outcome | 1999 |
Human small cell lung cancer NYH cells selected for resistance to the bisdioxopiperazine topoisomerase II catalytic inhibitor ICRF-187 demonstrate a functional R162Q mutation in the Walker A consensus ATP binding domain of the alpha isoform.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Amino Acid Substitution; Amsacrine; Animals; Antineoplastic Agents; Binding Sites; Carcinoma, Small Cell; Catalysis; CHO Cells; Consensus Sequence; Cricetinae; Cricetulus; DNA Damage; DNA Mutational Analysis; DNA Topoisomerases, Type II; DNA, Neoplasm; DNA, Single-Stranded; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Humans; Lung Neoplasms; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Protein Isoforms; Razoxane; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Thiobarbiturates; Topoisomerase II Inhibitors; Tumor Stem Cell Assay | 1999 |
Primary small cell carcinoma of the esophagus with achalasia in a patient in whom pro-gastrin-releasing peptide and neuron-specific enolase levels reflected the clinical course during chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Esophageal Achalasia; Esophageal Neoplasms; Esophagoscopy; Etoposide; Humans; Male; Middle Aged; Peptide Fragments; Peptides; Phosphopyruvate Hydratase; Prognosis; Recombinant Proteins; Sensitivity and Specificity; Tomography, X-Ray Computed; Treatment Outcome | 1999 |
Cancer-associated retinopathy during treatment for small-cell lung carcinoma.
Topics: Adrenal Cortex Hormones; Aged; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Calcium-Binding Proteins; Carboplatin; Carcinoma, Small Cell; Etoposide; Eye Proteins; Female; Hippocalcin; Humans; Immunosuppressive Agents; Lipoproteins; Lung Neoplasms; Nerve Tissue Proteins; Paraneoplastic Syndromes; Recoverin; Retinal Diseases; Vision, Low; Visual Acuity | 1999 |
Sodium and potassium excretion changes and bone marrow recovery after chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carcinoma, Small Cell; Carmustine; Cyclophosphamide; Cytarabine; Etoposide; Female; Hodgkin Disease; Humans; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma, Non-Hodgkin; Male; Multiple Myeloma; Potassium; Sodium | 1999 |
Marked increase in plasma ACTH with tumor reduction after chemotherapy in ectopic ACTH syndrome.
Topics: ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Adult; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Fatal Outcome; Female; Humans; Lung Neoplasms; Pyridines; Radiography; Suicide | 1999 |
[Atypical paraneoplastic myasthenic syndrome: Lambert-Eaton syndrome or myasthenia?].
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Carboplatin; Carcinoma, Neuroendocrine; Carcinoma, Small Cell; Combined Modality Therapy; Diagnosis, Differential; Etoposide; Female; Humans; Lambert-Eaton Myasthenic Syndrome; Lung; Lung Neoplasms; Middle Aged; Myasthenia Gravis; Paraneoplastic Syndromes; Radiotherapy Dosage; Tomography, X-Ray Computed | 1999 |
Delayed administration of sodium thiosulfate in animal models reduces platinum ototoxicity without reduction of antitumor activity.
Topics: Animals; Antidotes; Auditory Threshold; Carboplatin; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Ear, Middle; Etoposide; Female; Guinea Pigs; Humans; Lung Neoplasms; Male; Rats; Rats, Long-Evans; Rats, Nude; Thiosulfates; Tumor Cells, Cultured | 2000 |
[Evidence based chemotherapy for lung cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Etoposide; Evidence-Based Medicine; Humans; Lung Neoplasms; Survival Analysis | 2000 |
[A long-term survivor of extensive-stage small cell lung cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Lung Neoplasms; Male; Middle Aged; Mitomycin; Remission Induction; Survivors; Vindesine | 2000 |
Establishment and characterization of a prostatic small-cell carcinoma cell line (PSK-1) derived from a patient with Klinefelter syndrome.
Topics: Adult; Animals; Antineoplastic Agents; Carcinoma, Small Cell; Cell Division; Cisplatin; Dacarbazine; Doxorubicin; Etoposide; Fluorouracil; Humans; Karyotyping; Klinefelter Syndrome; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Phosphopyruvate Hydratase; Prostatic Neoplasms; Tumor Cells, Cultured | 2000 |
Extrapulmonary small-cell carcinoma: report of three cases and update of therapy and prognosis.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Esophageal Neoplasms; Etoposide; Humans; Male; Middle Aged; Pancreatic Neoplasms; Prognosis; Prostatic Neoplasms; Radiotherapy, Adjuvant | 2000 |
[Long-term results of small cell lung cancer treated by surgery combined with postoperative chemotherapy: a report of 65 patients].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Postoperative Period; Survival Rate; Vincristine | 1997 |
[Intra-abdominal desmoplastic small round-cell tumors. An entity among peritoneal carcinomatoses in young adults].
Topics: Abdominal Neoplasms; Abdominal Pain; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Doxorubicin; Etoposide; Fatal Outcome; Humans; Ifosfamide; Male; Middle Aged; Treatment Outcome | 2000 |
[VP-16 and VM-26 plus platinum drugs combined with radiotherapy in the treatment of small cell lung cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Cobalt Radioisotopes; Combined Modality Therapy; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Teniposide | 1998 |
Distinctive potentiating effects of cisplatin and/or ifosfamide combined with etoposide in human small cell lung carcinoma xenografts.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cell Division; Cisplatin; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Etoposide; Female; Gene Expression Regulation, Neoplastic; Humans; Ifosfamide; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Time Factors; Transplantation, Heterologous; Treatment Outcome | 2000 |
[Relapse of small cell carcinoma of the lung with metastasis to iris].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Iris Neoplasms; Lung Neoplasms; Male; Middle Aged; Radiotherapy, Adjuvant; Treatment Outcome | 2000 |
[Small cell carcinoma of the urinary bladder: a case report].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Cystectomy; Drug Administration Schedule; Etoposide; Humans; Male; Middle Aged; Neoplasm Staging; Treatment Outcome; Urinary Bladder Neoplasms | 2000 |
[Arg(6), D-Trp(7,9), N(me)Phe(8)]-substance P (6-11) (antagonist G) induces AP-1 transcription and sensitizes cells to chemotherapy.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Small Cell; Cell Division; CHO Cells; Cricetinae; Drug Synergism; Etoposide; Free Radical Scavengers; Glutathione; Growth Inhibitors; JNK Mitogen-Activated Protein Kinases; Lipid Peroxidation; Lung Neoplasms; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase Kinases; Oligopeptides; Oxidation-Reduction; Reactive Oxygen Species; Stimulation, Chemical; Transcription Factor AP-1; Transcription, Genetic; Tumor Cells, Cultured | 2000 |
[Combined chemotherapy after prolonged oral etoposide maintenance therapy in patients with small-cell lung cancer].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Phytogenic; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Remission Induction; Survival Analysis; Treatment Outcome | 2000 |
Similar outcome of elderly patients in intergroup trial 0096: Cisplatin, etoposide, and thoracic radiotherapy administered once or twice daily in limited stage small cell lung carcinoma.
Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Etoposide; Female; Humans; Lung Neoplasms; Male; Radiotherapy Dosage; Retrospective Studies; Survival Rate | 2000 |
DNA damage after chemotherapy correlates with tumor response and survival in small cell lung cancer patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Base Sequence; Carboplatin; Carcinoma, Small Cell; DNA Damage; DNA Primers; DNA, Neoplasm; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Mutation; Polymerase Chain Reaction; Prognosis; Pseudogenes | 2000 |
Asymptomatic brain metastases (BM) in small cell lung cancer (SCLC): MR-imaging is useful at initial diagnosis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Magnetic Resonance Imaging; Radiography; Reproducibility of Results; Retrospective Studies; Survival Analysis; Time Factors | 2000 |
Differential sensitivity to etoposide (VP-16)-induced S phase delay in a panel of small-cell lung carcinoma cell lines with G1/S phase checkpoint dysfunction.
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Small Cell; DNA Fragmentation; Etoposide; G1 Phase; Genes, p53; Humans; Lung Neoplasms; S Phase; Tumor Cells, Cultured | 2001 |
Small cell lung cancer as a cause of acute renal failure secondary to bilateral renal infiltration.
Topics: Acute Kidney Injury; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cytarabine; Etoposide; Humans; Liver; Lung Neoplasms; Male; Middle Aged; Tomography, X-Ray Computed; Treatment Outcome; Ultrasonography | 2000 |
[Determination of etoposide (VP16) in human serum by high performance liquid chromatography].
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Small Cell; Chromatography, High Pressure Liquid; Etoposide; Female; Humans; Lung Neoplasms; Male | 1998 |
Defective caspase-3 relocalization in non-small cell lung carcinoma.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Caspase 3; Caspase 8; Caspase 9; Caspases; Cell Nucleus; Cytochrome c Group; Cytosol; Enzyme Precursors; Etoposide; Fas Ligand Protein; Gamma Rays; Lung Neoplasms; Membrane Glycoproteins; Nucleic Acid Synthesis Inhibitors; Poly(ADP-ribose) Polymerases; Protein Transport; Proteins; Signal Transduction; Tumor Cells, Cultured | 2001 |
A new quinoline derivative MS-209 reverses multidrug resistance and inhibits multiorgan metastases by P-glycoprotein-expressing human small cell lung cancer cells.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Small Cell; Doxorubicin; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Etoposide; Humans; Lung Neoplasms; Male; Mice; Mice, SCID; Neoplasm Metastasis; Quinolines; Vincristine; Xenograft Model Antitumor Assays | 2001 |
[Outpatient chemotherapy for advanced lung cancer].
Topics: Adenocarcinoma; Adult; Aged; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Docetaxel; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Survival Rate; Taxoids | 2001 |
Donor-derived small cell lung carcinoma in a kidney transplant recipient.
Topics: Adrenocorticotropic Hormone; Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cushing Syndrome; Etoposide; Female; Humans; Hydrocortisone; Immunosuppressive Agents; Kidney Neoplasms; Kidney Transplantation; Tissue Donors | 2001 |
Improvement of anti-Hu-associated paraneoplastic sensory neuropathy after chemoradiotherapy in a small cell lung cancer patient.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Autoantibodies; Carboplatin; Carcinoma, Small Cell; Etoposide; Humans; Lung Neoplasms; Male; Paraneoplastic Polyneuropathy; Treatment Outcome | 2001 |
Editorial comments on 'Reduction of chemotherapy-induced febrile leucopenia by prophylactic use of ciprofloxacin and roxithromycin in small-cell lung cancer patients: an EORTC double-blind placebo-controlled phase III study'.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophylaxis; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Ciprofloxacin; Cyclophosphamide; Doxorubicin; Endpoint Determination; Etoposide; Fever; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Neutropenia; Palliative Care; Randomized Controlled Trials as Topic; Research Design; Roxithromycin | 2001 |
Lung cancer--time to move on from chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Irinotecan; Lung Neoplasms; Smoking; Survival Rate | 2002 |
Upregulation of Bcl-2 is involved in the mediation of chemotherapy resistance in human small cell lung cancer cell lines.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Small Cell; Caspases; Cell Survival; Cisplatin; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Fas Ligand Protein; fas Receptor; Humans; Lung Neoplasms; Membrane Glycoproteins; Mitochondria; Neoplasms, Experimental; Oligonucleotides, Antisense; Phenotype; Proto-Oncogene Proteins c-bcl-2; Transfection; Tumor Cells, Cultured; Up-Regulation | 2002 |
[Modulation of human small cell lung cancer cell line GLC4/ADR multidrug resistance in the inhibition of multidrug resistance-associated protein and its antisense].
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Carcinoma, Small Cell; Cell Cycle; Cell Division; Cloning, Molecular; Disease Models, Animal; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Gene Expression; Genes, MDR; Genetic Engineering; Humans; Lung Neoplasms; Mice; Mice, Nude; RNA, Antisense; Tumor Cells, Cultured | 2001 |
Technetium-99m methoxyisobutylisonitrile chest imaging for small-cell lung cancer. Relationship to chemotherapy response (six courses of combination of cisplatin and etoposide) and p-glycoprotein or multidrug resistance related protein expression.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Immunoenzyme Techniques; Lung Neoplasms; Male; Middle Aged; Multidrug Resistance-Associated Proteins; Prognosis; Radiopharmaceuticals; Technetium Tc 99m Sestamibi; Tomography, Emission-Computed, Single-Photon | 2001 |
[Chemotherapy for small-cell lung cancer (SCLC) patients with renal failure].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Humans; Kidney Neoplasms; Lung Neoplasms; Male; Middle Aged; Paraneoplastic Polyneuropathy; Renal Dialysis; Renal Insufficiency | 2002 |
Reply to the article "Editorial comments on 'reduction of chemotherapy-induced febrile leucopenia by prophylactic use of ciprofloxacin and roxithromycin in small-cell lung cancer patients: an EORTC double-blind placebo-controlled phase III study'", by P.
Topics: Antibiotic Prophylaxis; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Ciprofloxacin; Clinical Trials, Phase III as Topic; Cyclophosphamide; Double-Blind Method; Doxorubicin; Drug Therapy, Combination; Etoposide; Fever; Humans; Lung Neoplasms; Neutropenia; Palliative Care; Randomized Controlled Trials as Topic; Roxithromycin | 2002 |
Bradykinin antagonist dimer, CU201, inhibits the growth of human lung cancer cell lines in vitro and in vivo and produces synergistic growth inhibition in combination with other antitumor agents.
Topics: Animals; Antineoplastic Agents; Area Under Curve; Bradykinin; Bradykinin Receptor Antagonists; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Division; Cisplatin; Dimerization; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Etoposide; Gefitinib; Humans; Infusion Pumps; Injections, Intralesional; Injections, Intraperitoneal; Injections, Subcutaneous; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Oligopeptides; Paclitaxel; Quinazolines; Time Factors; Tumor Cells, Cultured; Vinblastine; Vinorelbine; Xenograft Model Antitumor Assays | 2002 |
Severe gustatory disorder caused by cisplatin and etoposide.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Lung Neoplasms; Middle Aged; Taste Disorders; Taste Threshold | 2002 |
The health-related quality of life and survival of small-cell lung cancer patients: results of a companion study to CALGB 9033.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Monitoring; Etoposide; Female; Humans; Linear Models; Male; Middle Aged; Prognosis; Proportional Hazards Models; Quality of Life; Surveys and Questionnaires; Survival Rate | 2002 |
[Therapeutic experiences using the new podophyllotoxin derivative VP 16-213 in malignant human tumors].
Topics: Adenocarcinoma; Bronchial Neoplasms; Carcinoma; Carcinoma, Small Cell; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Lung Neoplasms; Male; Middle Aged; Neoplasms; Ovarian Neoplasms; Podophyllotoxin; Prostatic Neoplasms; Remission, Spontaneous | 1975 |
Treatment of small cell anaplastic carcinoma of the lung with the oral solution of VP-16-213 (NSC 141540, 4'-demethylepipodophyllotoxin 9-(4,6-O-ethylidene-beta-D-glucopyranoside).
Topics: Administration, Oral; Aged; Carcinoma, Small Cell; Etoposide; Female; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Remission, Spontaneous; Solutions | 1977 |
Chemotherapy of small cell carcinoma of the lung with V.P. 16-213.
Topics: Bone Marrow; Carcinoma, Small Cell; Disability Evaluation; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Podophyllotoxin; Recurrence; Remission, Spontaneous; Time Factors | 1978 |
Radiation recall associated with VP-16-213 therapy.
Topics: Carcinoma, Small Cell; Erythema; Etoposide; Female; Humans; Lung Neoplasms; Middle Aged; Podophyllotoxin; Radiation Injuries; Radiation-Sensitizing Agents; Time Factors | 1979 |
Intensive induction therapy for small cell carcinoma of the lung.
Topics: Aged; Antineoplastic Agents; Bone Marrow; Carcinoma, Small Cell; Carmustine; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Procarbazine; Remission, Spontaneous; Vincristine | 1979 |
[Etoposide and cisplatin combination chemotherapy in a patient with small cell lung carcinoma under artificial hemodialysis].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Infusions, Intravenous; Kidney Failure, Chronic; Lung Neoplasms; Male; Renal Dialysis | 1992 |
Determinants of response to the DNA topoisomerase II inhibitors doxorubicin and etoposide in human lung cancer cell lines.
Topics: Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance; Etoposide; Humans; Lung Neoplasms; Tumor Cells, Cultured | 1992 |
Intrathecal administration of etoposide in the treatment of malignant meningitis: feasibility and pharmacokinetic data.
Topics: Adult; Carcinoma, Small Cell; Etoposide; Feasibility Studies; Humans; Injections, Spinal; Lung Neoplasms; Male; Meningitis; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1992 |
[Advances in the treatment of small cell lung cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Lung Neoplasms | 1992 |
A pilot study of intensive weekly chemotherapy for extensive disease small-cell lung carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Humans; Leucovorin; Lung Neoplasms; Methotrexate; Neoplasm Metastasis; Pilot Projects; Recurrence; Treatment Outcome; Vincristine | 1992 |
Multidrug sensitivity phenotype of human lung cancer cells associated with topoisomerase II expression.
Topics: Adenocarcinoma; Antineoplastic Agents; Blotting, Northern; Blotting, Southern; Camptothecin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Line; Cell Survival; Cisplatin; DNA Topoisomerases, Type II; DNA, Neoplasm; Doxorubicin; Drug Screening Assays, Antitumor; Etoposide; Fluorouracil; Humans; Lung Neoplasms; Phenotype; Restriction Mapping; RNA, Neoplasm; Teniposide | 1992 |
[Clinical study of etoposide (NK 171s, miniaturized capsule) in advanced small cell lung cancer].
Topics: Administration, Oral; Aged; Capsules; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged | 1992 |
[High dose chemotherapy with autologous bone marrow rescue for small cell lung cancer].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Bone Marrow Transplantation; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Etoposide; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Transplantation, Autologous; Vincristine | 1992 |
Quality of life during chemotherapy for small cell lung cancer. II. A longitudinal study of the EORTC Core Quality of Life Questionnaire and comparison with the Sickness Impact Profile.
Topics: Aged; Attitude to Health; Carcinoma, Small Cell; Etoposide; Follow-Up Studies; Humans; Longitudinal Studies; Lung Neoplasms; Neoplasm Staging; Probability; Quality of Life; Surveys and Questionnaires; Teniposide | 1992 |
Differential effects of amsacrine and epipodophyllotoxins on topoisomerase II cleavage in the human c-myc protooncogene.
Topics: Amsacrine; Animals; Base Sequence; Binding Sites; Carcinoma, Small Cell; Cell Line; DNA Damage; DNA Topoisomerases, Type II; DNA, Neoplasm; Etoposide; Genes, myc; Humans; Leukemia L1210; Lung Neoplasms; Mice; Molecular Sequence Data; Promoter Regions, Genetic; Restriction Mapping; Substrate Specificity; Teniposide | 1992 |
[Pilot phase II trial of high-dose etoposide combined with cisplatin in the treatment of refractory lung cancer].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Metastasis; Pilot Projects; Sarcoma | 1992 |
Treatment of relapse of small cell lung cancer in selected patients with the initial combination chemotherapy carboplatin, etoposide, and epirubicin.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Epirubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Tomography, X-Ray Computed | 1992 |
Antitumor activity of magainin analogues against human lung cancer cell lines.
Topics: Antimicrobial Cationic Peptides; Antineoplastic Agents; Carcinoma, Small Cell; Cisplatin; Etoposide; Fibroblasts; Humans; Lung Neoplasms; Peptides; Tumor Cells, Cultured | 1992 |
[The effect of combination chemotherapy with cisplatin, vincristine, doxorubicin and etoposide (Tokushima-CODE: T-CODE) against lung cancer].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Drug Administration Schedule; Etoposide; Humans; Lung Neoplasms; Middle Aged; Pilot Projects; Vincristine | 1992 |
[A case with delayed-onset radiation pneumonitis suspected to be induced by oral etoposide].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Etoposide; Humans; Lung Neoplasms; Male; Middle Aged; Pneumonia; Radiation Injuries; Radiotherapy, High-Energy | 1992 |
Carboplatin-containing regimens for small cell lung cancer: implications for management in the elderly.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Clinical Protocols; Cyclophosphamide; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neutropenia; Remission Induction; Survival Rate; Vincristine | 1992 |
Treatment of relapse of small cell lung cancer in selected patients with the initial combination chemotherapy with carboplatin, etoposide and epirubicin.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Epirubicin; Etoposide; Humans; Lung Neoplasms | 1992 |
Multidrug resistance in a small cell lung cancer line: rapid selection with etoposide and differential chemosensitization with cyclosporin A.
Topics: Alkalies; Biological Transport; Carcinoma, Small Cell; Cell Division; Cell Nucleus; Cyclosporine; DNA Topoisomerases, Type II; Drug Resistance; Etoposide; Lung Neoplasms; Organelles; Phenotype; Ribonucleases; Tumor Cells, Cultured | 1992 |
Small cell carcinoma of the gallbladder: clinical course and response to chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Etoposide; Gallbladder Neoplasms; Humans; Male; Middle Aged | 1992 |
[A case of small cell undifferentiated carcinoma (SCUC) of the rectum treated with etoposide, cis-platinum and radiotherapy].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Etoposide; Female; Humans; Radiotherapy Dosage; Rectal Neoplasms; Remission Induction | 1992 |
Relationships between various uses of antineoplastic drug-interaction terms.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Synergism; Etoposide; Humans; Leukemia P388; Lung Neoplasms; Terminology as Topic; Tumor Cells, Cultured | 1992 |
Pharmacodynamics of three daily infusions of etoposide in patients with extensive-stage small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Etoposide; Hematologic Diseases; Humans; Lung Neoplasms; Metabolic Clearance Rate; Middle Aged; Models, Statistical | 1992 |
[Chemotherapy with cisplatin, adriamycin, etoposide and ifosfamide in microcytic lung carcinoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged | 1992 |
An adriamycin-resistant subline is more sensitive than the parent human small cell lung cancer cell line to lonidamine.
Topics: Antineoplastic Agents; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Etoposide; Humans; Indazoles; Lung Neoplasms; Tumor Cells, Cultured | 1992 |
[The treatment of small cell lung cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cyclophosphamide; Etoposide; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Prednisone; Procarbazine; Prospective Studies; Survival Rate; Vincristine | 1992 |
Establishment and characterization of an etoposide-resistant human small cell lung cancer cell line.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Small Cell; DNA Topoisomerases, Type II; Drug Resistance; Etoposide; Glutathione; Humans; Lung Neoplasms; Membrane Glycoproteins; RNA, Messenger; Tumor Cells, Cultured | 1992 |
Doxorubicin sensitivity pattern in a panel of small-cell lung-cancer cell lines: correlation to etoposide and vincristine sensitivity and inverse correlation to carmustine sensitivity.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Small Cell; Carmustine; Cell Division; Cisplatin; Cytarabine; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Etoposide; Humans; Lung Neoplasms; Membrane Glycoproteins; Tumor Cells, Cultured | 1992 |
Cardiac tamponade resulting from recurrent small-cell carcinoma of the uterine cervix temporarily responding to CE/CAV chemotherapy: report of a case.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cardiac Tamponade; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Neoplasm Recurrence, Local; Uterine Cervical Neoplasms; Vincristine | 1992 |
Weekly dose-intensive chemotherapy in patients with small-cell lung cancer: a pilot study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Middle Aged; Pilot Projects; Recombinant Proteins; Remission Induction; Survival Analysis; Vincristine | 1992 |
Obstructing endobronchial bands complicating radiation therapy for lung carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bronchi; Bronchoscopy; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Fibrosis; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Prednisone; Radiotherapy; Radiotherapy Dosage; Vincristine | 1992 |
Case report: cisplatin-induced hemolytic uremic syndrome.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Carcinoma, Small Cell; Cisplatin; Etoposide; Hemolytic-Uremic Syndrome; Humans; Lung Neoplasms; Male; Middle Aged; Spinal Neoplasms | 1991 |
In vitro and in vivo modulation of multi-drug resistance with amiodarone.
Topics: Adult; Amiodarone; Biological Transport; Carcinoma, Small Cell; Cell Line; Cell Survival; Colonic Neoplasms; DNA Damage; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Etoposide; Female; Humans; Kinetics; Lung Neoplasms; Male; Neoplasms; Tumor Stem Cell Assay; Vincristine | 1991 |
[Surgical treatment of esophago-pleural fistula caused by chemotherapy for lung cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Esophageal Fistula; Esophagoplasty; Etoposide; Female; Fistula; Humans; Lung Neoplasms; Pleural Diseases | 1991 |
Limited small cell lung cancer: the effect of radiotherapy on local control following response to chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Australia; Carboplatin; Carcinoma, Small Cell; Cyclophosphamide; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Prospective Studies; Survival Analysis; Survival Rate; Vincristine | 1991 |
A retrospective analysis of patients receiving surgery after chemotherapy for small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Nimustine; Pneumonectomy; Prognosis; Retrospective Studies; Survival Rate; Vincristine | 1991 |
Intensive therapy for small-cell lung cancer using carboplatin alternating with cisplatin, ifosfamide, etoposide, mid-cycle vincristine, and radiotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Survival Rate; Vincristine | 1991 |
Intercalated radio-chemotherapy in small cell lung cancer: toxicity and implications for future regimens.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Pulmonary Fibrosis; Radiation Injuries; Radiotherapy Dosage | 1991 |
[Phase II study of lung cancer--evaluation of new drug in small cell lung cancer (SCLC) and phase II testing of analogues].
Topics: Antineoplastic Agents; Carcinoma, Small Cell; Cisplatin; Drug Evaluation; Drug Resistance; Etoposide; Humans; Lung Neoplasms | 1991 |
Vindesine and etoposide chemotherapy in the management of patients with small cell lung cancer and poor prognosis.
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Injections, Intravenous; Lung Neoplasms; Male; Middle Aged; Prognosis; Remission Induction; Retrospective Studies; Serum Albumin; Survival Rate; Vincristine; Vindesine | 1991 |
Intensive weekly chemotherapy for the treatment of extensive-stage small-cell lung cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Pilot Projects; Survival Rate; Vincristine | 1991 |
[Successful treatment of a pretreated elderly case of small-cell lung carcinoma with continuous five-day intravenous infusion of cisplatin plus etoposide].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Etoposide; Humans; Infusions, Intravenous; Lung Neoplasms; Lymphatic Metastasis; Male | 1991 |
Lack of cross-resistance to fostriecin in a human small-cell lung carcinoma cell line showing topoisomerase II-related drug resistance.
Topics: Alkenes; Antibiotics, Antineoplastic; Carcinoma, Small Cell; Cell Line; Cell Nucleus; DNA Topoisomerases, Type II; Drug Resistance; Drug Screening Assays, Antitumor; Etoposide; Humans; Lung Neoplasms; Methotrexate; Polyenes; Pyrones; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1991 |
Resectability of small-cell lung cancer following induction chemotherapy in patients with limited disease (stage II-IIIb).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Feasibility Studies; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prospective Studies; Vincristine | 1991 |
[A pilot study of etoposide, split-dose cisplatin and THP in small cell lung cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Drug Administration Schedule; Etoposide; Humans; Lung Neoplasms; Pilot Projects; Survival Rate | 1991 |
[The evaluation of the cardiotoxicity of 4'-epidoxorubicin at high doses].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Dose-Response Relationship, Drug; Echocardiography; Epirubicin; Etoposide; Female; Heart; Humans; Lung Neoplasms; Male; Middle Aged; Myocardium | 1991 |
Clinical pharmacology and toxicity of low daily administration of oral etoposide in advanced lung cancer patients.
Topics: Adenocarcinoma; Administration, Oral; Aged; Aged, 80 and over; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged | 1991 |
[Alternating chemotherapeutic treatment in patients with localized undifferentiated small-cell carcinoma of the lung].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lomustine; Lung Neoplasms; Methotrexate; Procarbazine; Remission Induction; Time Factors; Vincristine | 1991 |
Salvage chemotherapy with CCNU and methotrexate for small cell lung cancer resistant to CAV/PE alternating chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Resistance; Etoposide; Female; Humans; Leukopenia; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Remission Induction; Salvage Therapy; Vincristine | 1991 |
Pharmacokinetics of an etoposide infused over three days: concomitant infusion with cisplatin.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Infusions, Intravenous; Leukopenia; Lung Neoplasms; Male; Metabolic Clearance Rate; Middle Aged; Regression Analysis | 1991 |
Non-P-glycoprotein-mediated multidrug resistance in a small cell lung cancer cell line: evidence for decreased susceptibility to drug-induced DNA damage and reduced levels of topoisomerase II.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Carcinoma, Small Cell; DNA Damage; DNA Topoisomerases, Type II; Drug Resistance; Etoposide; Gene Expression; Humans; In Vitro Techniques; Lung Neoplasms; Membrane Glycoproteins; Molecular Sequence Data; Oligonucleotides; Tumor Cells, Cultured | 1991 |
Chemotherapy as treatment of choice in extrapulmonary undifferentiated small cell carcinomas.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Digestive System Neoplasms; Doxorubicin; Etoposide; Female; Genital Neoplasms, Female; Humans; Male; Middle Aged; Mitomycins; Neoplasm Staging; Neoplasms, Unknown Primary; Vincristine | 1990 |
Evaluation of high-dose etoposide combined with cisplatin for treating relapsed small cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Colony-Stimulating Factors; Drug Evaluation; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Granulocytes; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Recombinant Proteins; Remission Induction; Survival Rate | 1990 |
[Phase II study with etoposide/vincristine in small cell bronchial cancer (extensive disease)].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Palliative Care; Vincristine | 1990 |
Cytotoxic chemotherapy induces cell differentiation in small-cell lung carcinoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cell Differentiation; Cyclophosphamide; Cytoplasmic Granules; Desmosomes; Doxorubicin; Drug Resistance; Etoposide; Female; Humans; Immunohistochemistry; Keratins; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Molecular Weight; Neoplasm Staging; Phenotype; Phosphopyruvate Hydratase; Survival Rate | 1991 |
[An elderly case of small cell lung cancer showing a good partial response by chronic daily administration of oral etoposide].
Topics: Administration, Oral; Aged; Aged, 80 and over; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Humans; Lung Neoplasms; Male; Remission Induction; Time Factors | 1991 |
Intensive weekly chemotherapy for good-prognosis patients with small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Follow-Up Studies; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Survival Rate | 1991 |
[A case of remission of multiple retroperitoneal lymph node relapse in small cell lung cancer treated with oral etoposide].
Topics: Administration, Oral; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Etoposide; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Retroperitoneal Neoplasms | 1991 |
Surgical treatment for limited small-cell lung cancer. The University of Toronto Lung Oncology Group experience.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Survival Rate; Vincristine | 1991 |
[A case of small cell carcinoma of the lung responding well to oral etoposide therapy].
Topics: Administration, Oral; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Middle Aged; Peritoneal Neoplasms | 1991 |
Detection of multidrug resistance and quantification of responses of human tumour cells to cytotoxic agents using flow cytometric spectral shift analysis of Hoechst 33,342-DNA fluorescence.
Topics: Benzimidazoles; Carcinoma, Small Cell; Cell Line, Transformed; Cell Nucleus; Cell Survival; DNA, Neoplasm; Drug Resistance; Etoposide; Flow Cytometry; Fluorescent Dyes; Humans; Lung Neoplasms; Lymphocytes; Tumor Cells, Cultured | 1991 |
A feasibility study of testing new drugs for small-cell lung cancer in patients with a poor performance status.
Topics: Adult; Aged; Carcinoma, Small Cell; Drug Evaluation; Etoposide; Feasibility Studies; Humans; Lung Neoplasms; Middle Aged | 1991 |
Small-cell lung cancer in elderly patients: the case for chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Prednisone; Retrospective Studies; Survival Rate; Vincristine | 1991 |
[The efficacy and side effects of chemotherapy for primary lung cancer with cisplatin and etoposide].
Topics: Adenocarcinoma; Administration, Oral; Angina Pectoris; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cisplatin; Drug Evaluation; Etoposide; Humans; Infusions, Intravenous; Kidney; Leukopenia; Lung Neoplasms | 1991 |
[Small-cell lung carcinoma. Inappropriate antidiuretic hormone secretion revealed by chemotherapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Inappropriate ADH Syndrome; Lung Neoplasms | 1991 |
Correlation of in vitro drug sensitivity testing of long-term small cell lung cancer cell lines with response and survival.
Topics: Carcinoma, Small Cell; Cell Line; Cisplatin; Drug Screening Assays, Antitumor; Etoposide; Humans; In Vitro Techniques; Lung Neoplasms; Time Factors; Tumor Cells, Cultured | 1990 |
Reduced DNA topoisomerase II activity and drug-induced DNA cleavage activity in an adriamycin-resistant human small cell lung carcinoma cell line.
Topics: Amsacrine; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Small Cell; Cell Cycle; Cell Division; DNA; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance; Etoposide; Humans; Lung Neoplasms; Membrane Glycoproteins; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Verapamil | 1990 |
Characterization of an etoposide-resistant human small-cell lung cancer cell line.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Small Cell; DNA Topoisomerases, Type II; Drug Resistance; Etoposide; Humans; Lung Neoplasms; Membrane Glycoproteins; Phenotype; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured | 1990 |
[An elderly case of small cell lung cancer showing complete response by oral administration of etoposide].
Topics: Administration, Oral; Aged; Aged, 80 and over; Carcinoma, Small Cell; Etoposide; Female; Humans; Lung Neoplasms | 1990 |
Comparison of DNA cleavage induced by etoposide and doxorubicin in two human small-cell lung cancer lines with different sensitivities to topoisomerase II inhibitors.
Topics: Carcinoma, Small Cell; DNA; DNA Damage; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1990 |
Phase II trial of daily oral VP-16 in refractory small cell lung cancer: a Hoosier Oncology Group study.
Topics: Administration, Oral; Carcinoma, Small Cell; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Hematologic Diseases; Humans; Lung Neoplasms; Male; Remission Induction; Survival Rate | 1990 |
Single-agent oral etoposide for elderly small cell lung cancer patients.
Topics: Aged; Aged, 80 and over; Carcinoma, Small Cell; Etoposide; Female; Humans; Lung Neoplasms; Male; Neoplasm Staging; Remission Induction | 1990 |
Chronic daily administration of oral etoposide.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Small Cell; Drug Administration Schedule; Drug Evaluation; Etoposide; Humans; Lung Neoplasms; Lymphoma, Non-Hodgkin; Middle Aged; Neoplasms; Neoplasms, Germ Cell and Embryonal | 1990 |
Clinical pharmacodynamics of continuous-infusion etoposide.
Topics: Adult; Aged; Blood Cell Count; Carcinoma, Small Cell; Chromatography, High Pressure Liquid; Drug Resistance; Etoposide; Humans; Infusions, Intravenous; Kidney Function Tests; Leukocyte Count; Liver Function Tests; Lung Neoplasms; Middle Aged; Neoplasms | 1990 |
Etoposide, carboplatin, cyclophosphamide and vincristine in previously untreated patients with small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cyclophosphamide; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neutropenia; Organoplatinum Compounds; Vincristine | 1990 |
[A combination phase II study of adriamycin, CDDP and etoposide in small cell lung cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Urea Nitrogen; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nausea | 1990 |
[Acute myocardial infarction induced by lung cancer chemotherapy with cisplatin and etoposide].
Topics: Adenocarcinoma; Aged; Carcinoma, Small Cell; Cisplatin; Electrocardiography; Etoposide; Humans; Lung Neoplasms; Male; Middle Aged; Myocardial Infarction | 1990 |
Phase I trial of high-dose etoposide, high-dose cisplatin, and reinfusion of autologous bone marrow for lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Drug Evaluation; Etoposide; Humans; Lung Neoplasms; Middle Aged | 1990 |
Therapy for poor-risk patients with small-cell lung cancer using bolus ifosfamide and oral etoposide.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Prognosis; Risk Factors | 1990 |
Carboplatin, etoposide, and ifosfamide as intensive chemotherapy for small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Neutropenia; Organoplatinum Compounds; Pilot Projects; Remission Induction; Survival Rate; Thrombocytopenia | 1990 |
Antagonistic effect of aclarubicin on the cytotoxicity of etoposide and 4'-(9-acridinylamino)methanesulfon-m-anisidide in human small cell lung cancer cell lines and on topoisomerase II-mediated DNA cleavage.
Topics: Aclarubicin; Amsacrine; Carcinoma, Small Cell; Cell Survival; DNA Damage; DNA, Neoplasm; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1990 |
Combination cyclophosphamide and etoposide in treatment of small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Survival Rate | 1990 |
[Nerve conduction velocity following high-dose vincristine in the treatment of small cell bronchial cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Dose-Response Relationship, Drug; Epirubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Reaction Time; Synaptic Transmission; Vincristine | 1990 |
[Chemotherapy of small cell bronchial cancer with a combination of carboplatin, vincristine and etoposide].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Drug Evaluation; Etoposide; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Vincristine | 1990 |
Addition of verapamil and tamoxifen to the initial chemotherapy of small cell lung cancer. A phase I/II study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Doxorubicin; Drug Administration Schedule; Drug Evaluation; Drug Resistance; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Tamoxifen; Time Factors; Verapamil; Vincristine | 1990 |
Small cell bronchogenic carcinoma: a cyclical alternating combination of epirubicin plus cisplatin and cyclophosphamide plus etoposide.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Epirubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged | 1990 |
Ifosfamide and mesna in combination with other cytostatic drugs in the treatment of patients with advanced cancer.
Topics: Adolescent; Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Ifosfamide; Leukopenia; Lung Neoplasms; Male; Mesna; Middle Aged; Nausea; Ovarian Neoplasms; Sarcoma, Ewing; Testicular Neoplasms; Vomiting | 1990 |
Ifosfamide, doxorubicin and etoposide in small cell lung cancer patients with poor prognosis.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Prognosis | 1990 |
Clinical trials referral resource. Small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Colony-Stimulating Factors; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Interferon Type I; Lung Neoplasms | 1990 |
Serum neuron-specific enolase as a marker of small-cell carcinoma of the esophagus.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Brain Neoplasms; Carcinoma, Small Cell; Cisplatin; Esophageal Neoplasms; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Phosphopyruvate Hydratase; Skin Neoplasms; Vincristine | 1990 |
Low-dose oral etoposide: a new role for an old drug?
Topics: Administration, Oral; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Humans; Lung Neoplasms; Remission Induction | 1990 |
Prolonged administration of oral etoposide in patients with relapsed or refractory small-cell lung cancer: a phase II trial.
Topics: Administration, Oral; Aged; Aged, 80 and over; Carcinoma, Small Cell; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Remission Induction; Survival Rate; Thrombocytopenia | 1990 |
Interaction of recombinant human tumor necrosis factor and etoposide in human lung cancer cell lines.
Topics: Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Division; Cell Line; Cell Survival; Combined Modality Therapy; Doxorubicin; Drug Interactions; Etoposide; Humans; Lung Neoplasms; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1990 |
Accelerated radiation therapy in small cell lung cancer: rationale and limitation in its utility.
Topics: Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Lung Neoplasms; Radiotherapy Dosage | 1990 |
Small cell carcinoma of the ovary: a rapidly lethal tumor occurring in the young.
Topics: Adolescent; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Small Cell; Child; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Etoposide; Female; Humans; Microscopy, Electron; Neoplasm Metastasis; Ovarian Neoplasms; Vinblastine; Vincristine | 1985 |
[The relationship between morphological manifestations and cell kinetic changes of human lung cancer cells after exposure to chemotherapeutic agents].
Topics: Adenocarcinoma; Antineoplastic Agents; Bleomycin; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cell Cycle; Cell Line; Cisplatin; DNA, Neoplasm; Etoposide; Flow Cytometry; Humans; Lung Neoplasms; Peplomycin | 1986 |
Multidrug resistance in a human small cell lung cancer cell line selected in adriamycin.
Topics: Animals; Antibodies, Monoclonal; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Small Cell; Cell Line; Colchicine; Daunorubicin; Doxorubicin; Drug Resistance; Enzyme-Linked Immunosorbent Assay; Epirubicin; Etoposide; Glycoproteins; Gramicidin; Humans; Immunosorbent Techniques; Isoxazoles; Lung Neoplasms; Menogaril; Mice; Mice, Inbred BALB C; Mitoxantrone; Nogalamycin; Phenotype; Vinblastine; Vincristine | 1987 |
Phase I/II study of recombinant human granulocyte colony-stimulating factor in patients receiving intensive chemotherapy for small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Colony-Stimulating Factors; Doxorubicin; Drug Evaluation; Etoposide; Granulocyte Colony-Stimulating Factor; Hemoglobins; Humans; Ifosfamide; Leukocyte Count; Lung Neoplasms; Mesna; Neutrophils; Platelet Count; Recombinant Proteins | 1988 |
Vinblastine, cisplatin, cyclophosphamide, bleomycin, doxorubicin, and etoposide in the treatment of small cell carcinoma of the ovary.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Neoplasm Staging; Ovarian Neoplasms; Remission Induction; Vinblastine | 1989 |
A phase II study of oral etoposide in elderly patients with small cell lung cancer.
Topics: Administration, Oral; Aged; Aged, 80 and over; Carcinoma, Small Cell; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Palliative Care | 1989 |
Cisplatin and etoposide (VP-16) as a single regimen for small cell lung cancer. A phase II trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Remission Induction | 1989 |
Oral etoposide for a 95-year-old patient with small cell lung cancer.
Topics: Aged; Aged, 80 and over; Carcinoma, Small Cell; Etoposide; Humans; Lung Neoplasms; Male | 1989 |
High dose etoposide for brain metastases of small cell lung cancer. A phase II study. The EORTC Lung Cancer Cooperative Group.
Topics: Adult; Aged; Brain Neoplasms; Carcinoma, Small Cell; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged | 1989 |
High-dose etoposide for meningeal carcinomatosis in patients with small cell lung cancer.
Topics: Aged; Carcinoma, Small Cell; Etoposide; Humans; Lung Neoplasms; Meningeal Neoplasms; Middle Aged | 1989 |
A phase I-II study of sequential infusion VP-16 and cisplatin therapy in advanced lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Remission Induction; Safety | 1989 |
[High-frequency atrial arrhythmia induced by a cisplatin-etoposide combination].
Topics: Antineoplastic Combined Chemotherapy Protocols; Arrhythmias, Cardiac; Carcinoma, Small Cell; Cisplatin; Electrocardiography; Etoposide; Humans; Lung Neoplasms; Male; Middle Aged | 1989 |
Cyclophosphamide, vincristine, cisplatin, VP-16 and radiation therapy in extensive small-cell lung cancer. A Southwest Oncology Group Study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Neutropenia; Pneumonia; Radiation Injuries; Remission Induction; Thrombocytopenia; Vincristine | 1989 |
[Pilot phase II study of hybrid chemotherapy of CAV-PVP in small cell lung cancer (SCLC)].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Leukopenia; Lung Neoplasms; Male; Pilot Projects; Remission Induction; Thrombocytopenia; Vincristine | 1989 |
[Adriamycin, cisplatin, and etoposide combination chemotherapy for small cell lung cancer].
Topics: Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Leukopenia; Lung Neoplasms; Male; Pilot Projects; Remission Induction; Thrombocytopenia | 1989 |
Patients at risk of chemotherapy-associated toxicity in small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Risk Factors; Vincristine | 1989 |
Acute phase reaction during chemotherapy in small cell lung cancer.
Topics: Acute-Phase Reaction; Antineoplastic Combined Chemotherapy Protocols; C-Reactive Protein; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Inflammation; Lung Neoplasms; Vincristine | 1989 |
Rapidly expanding exophthalmos: an unusual presentation of small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Exophthalmos; Humans; Lung Neoplasms; Male; Middle Aged; Orbital Neoplasms; Remission Induction | 1989 |
Systemic therapy for small-cell lung cancer: old themes replayed, new ones awaited.
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lomustine; Lung Neoplasms; Methotrexate; Mitomycin; Mitomycins | 1989 |
Intensive chemotherapy with autologous bone marrow transplantation for small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Follow-Up Studies; Humans; Lung Neoplasms; Melphalan; Organoplatinum Compounds; Prognosis; Radiotherapy Dosage; Remission Induction; Vincristine | 1989 |
A simple outpatient treatment with oral ifosfamide and oral etoposide for patients with small cell lung cancer (SCLC).
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Prospective Studies | 1989 |
Successful management of small cell carcinoma of the bladder with cisplatin and etoposide.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Male; Middle Aged; Urinary Bladder Neoplasms | 1989 |
Limited small cell lung cancer: possible prognostic impact of initial chemotherapy doses.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Humans; Lung Neoplasms; Prognosis; Radiotherapy Dosage | 1989 |
High-dose etoposide and autologous bone marrow transplantation as intensification treatment in small cell lung cancer: a pilot study.
Topics: Adult; Bone Marrow Transplantation; Carcinoma, Small Cell; Cell Survival; Dose-Response Relationship, Drug; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Pilot Projects; Time Factors; Transplantation, Autologous | 1989 |
Small cell carcinoma of the esophagus. The Memorial Hospital experience 1970 to 1987.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Evaluation; Esophageal Neoplasms; Etoposide; Female; Humans; Male; Prognosis; Vincristine | 1989 |
Combination chemotherapy with cisplatin and etoposide associated with radiotherapy in the treatment of small-cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Prospective Studies | 1989 |
[Circulating hematopoietic stem cells in patients with small cell lung cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Carcinoma, Small Cell; Cisplatin; Etoposide; Hematopoietic Stem Cells; Humans; Lung Neoplasms; Male; Middle Aged | 1989 |
Carboplatin, ifosfamide and etoposide with mid-course vincristine and thoracic radiotherapy for 'limited' stage small cell carcinoma of the bronchus.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Vincristine | 1989 |
Complete remission of refractory small cell carcinoma of the pancreas with cisplatin and etoposide.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Male; Middle Aged; Pancreatic Neoplasms; Remission Induction; Tomography, X-Ray Computed; Ultrasonography | 1989 |
[A case of intra-arterial infusion chemotherapy in small cell lung cancer with liver metastases].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Etoposide; Hepatic Artery; Humans; Infusions, Intra-Arterial; Iodized Oil; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Remission Induction; Suspensions | 1989 |
Differentiation of human variant small cell lung cancer cell lines to a classic morphology by retinoic acid.
Topics: Antigens, Neoplasm; Antigens, Surface; Blotting, Northern; Carcinoma, Small Cell; Cell Differentiation; Cell Division; Dopa Decarboxylase; Doxorubicin; Etoposide; Gene Expression Regulation, Neoplastic; Humans; In Vitro Techniques; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Tretinoin; Tumor Cells, Cultured | 1989 |
Treatment of small cell lung cancer by eight weeks chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Humans; Leucovorin; Lung Neoplasms; Methotrexate; Middle Aged; Time Factors; Vincristine | 1989 |
Resolution of small cell lung cancer intracranial metastases with standard dose chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged | 1989 |
Treatment strategies in relation to drug action.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; DNA Topoisomerases, Type II; Etoposide; Hodgkin Disease; Humans; Leukemia; Lung Neoplasms; Lymphoma, Non-Hodgkin; Neoplasms; Podophyllotoxin; Teniposide | 1987 |
Cyclophosphamide, doxorubicin, and vincristine in etoposide- and cisplatin-resistant small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Organoplatinum Compounds; Vincristine | 1987 |
Vincristine and etoposide: an effective chemotherapy regimen with reduced toxicity in extensive small-cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Etoposide; Humans; Lung Neoplasms; Time Factors; Vincristine | 1987 |
Unchanged pharmacokinetics of VP-16-213 (etoposide, NSC 141540) during concomitant administration of doxorubicin and cyclophosphamide.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Kinetics; Lung Neoplasms; Male; Middle Aged | 1987 |
Carboplatin (CBDCA, JM-8) and VP-16-213 in previously untreated patients with small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Organoplatinum Compounds | 1987 |
Surgery after initial chemotherapy for localized small-cell carcinoma of the lung.
Topics: Actuarial Analysis; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Necrosis; Neoplasm Staging; Prospective Studies | 1987 |
Acute nonlymphocytic leukemia following etoposide and cisplatin combination chemotherapy for advanced non-small-cell carcinoma of the lung.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Karyotyping; Leukemia; Lung Neoplasms; Male; Middle Aged | 1987 |
Ifosfamide, etoposide, and thoracic irradiation therapy in 163 patients with unresectable small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Etoposide; Evaluation Studies as Topic; Female; Humans; Ifosfamide; Lorazepam; Lung Neoplasms; Male; Mesna; Metoclopramide; Middle Aged | 1987 |
Effective chemotherapy for small cell carcinoma of the esophagus.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Esophageal Neoplasms; Etoposide; Humans; Male; Vincristine | 1987 |
Phase II study of oral VP-16-213 in small cell lung cancer.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Carcinoma, Small Cell; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged | 1987 |
[COMVp regimen in the treatment of small cell lung cancer--report of 106 patients].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Etoposide; Female; Humans; Lung Neoplasms; Male; Methotrexate; Vincristine | 1987 |
Retreatment with the induction regimen in small cell lung cancer relapsing after an initial response to short term chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Etoposide; Humans; Lung Neoplasms; Middle Aged; Recurrence; Remission Induction | 1987 |
[High-doses chemotherapy followed by bone marrow autograft in the treatment of small cell bronchial cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carcinoma, Small Cell; Carmustine; Combined Modality Therapy; Etoposide; Humans; Lung Neoplasms; Melphalan; Procarbazine | 1987 |
Reinduction chemotherapy in small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bacterial Outer Membrane Proteins; Bacterial Proteins; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Administration Schedule; Etoposide; Humans; Lung Neoplasms; Membrane Glycoproteins; Peptidyl-Dipeptidase A; Vincristine | 1987 |
Cutaneous pathology following etoposide therapy.
Topics: Adult; Aged; Biopsy; Carcinoma, Small Cell; Drug Eruptions; Etoposide; Female; Humans; Leukemia, Lymphoid; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Male; Middle Aged | 1987 |
Continuous infusion of etoposide, bolus administration of cisplatin, and simultaneous radiation therapy in previously treated patients with small cell bronchogenic carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged | 1988 |
The multidrug resistant phenotype in clinical practice; evaluation of cross resistance to ifosfamide and mesna after VP16-213, doxorubicin and vincristine (VPAV) for small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Doxorubicin; Drug Resistance; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Mesna; Middle Aged; Vincristine | 1988 |
[Clinical evaluation of serum NSE (neuron specific enolase) levels in cases of small cell lung cancer].
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Phosphopyruvate Hydratase; Radiography, Thoracic | 1988 |
Results of a combined chemo-radiotherapeutic program in 61 patients affected by small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Procarbazine; Radiography; Vincristine; Vomiting | 1988 |
Summary of recent clinical experience in whole-body hyperthermia combined with chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dacarbazine; Doxorubicin; Etoposide; Evaluation Studies as Topic; Female; Humans; Hyperthermia, Induced; Lung Neoplasms; Male; Melanoma; Vincristine; Vindesine | 1988 |
Phase II study of an intensive combination chemotherapy with cisplatin, adriamycin, etoposide and cyclophosphamide (CAVE) in small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Prognosis; Time Factors | 1988 |
[The role of surgical treatment in the combination therapy of small cell lung cancer (SCLC)].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Vincristine | 1988 |
Pilot study of a continuous five-day intravenous infusion of etoposide concomitant with cisplatin in selected patients with advanced cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cisplatin; Etoposide; Female; Histiocytoma, Benign Fibrous; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Pilot Projects; Stomach Neoplasms; Tongue Neoplasms | 1988 |
[A combination chemotherapy of cisplatin and etoposide in small cell lung cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged | 1988 |
Carboplatin (JM8), etoposide (VP16) and thoracic irradiation for small cell lung cancer (S.C.L.C.): an evaluation of lung toxicity.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Combined Modality Therapy; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Pneumonia; Pulmonary Fibrosis; Radiation Injuries | 1988 |
Etoposide (VP-16) and cytosine arabinoside in the treatment of relapsed small-cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cytarabine; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local | 1988 |
The pharmacokinetics of high dose cyclophosphamide and high dose etoposide.
Topics: Carcinoma, Small Cell; Cyclophosphamide; Drug Therapy, Combination; Etoposide; Half-Life; Humans; Infusions, Intravenous; Lung Neoplasms; Teratoma | 1988 |
Etoposide and split-dose cisplatin in small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged | 1988 |
VP-16 and carboplatin in previously untreated patients with extensive small cell lung cancer: a study of the National Cancer Institute of Canada Clinical Trials Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Female; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Organoplatinum Compounds | 1988 |
In vitro chemical eradication of small cell lung cancer: application in autologous bone marrow transplantation.
Topics: Antineoplastic Agents; Bone Marrow; Bone Marrow Transplantation; Carbazoles; Carcinoma, Small Cell; Cell Line; Cell Survival; Cisplatin; Cyclophosphamide; Doxorubicin; Ellipticines; Etoposide; Humans; Intercalating Agents; Lung Neoplasms; Transplantation, Autologous; Tumor Cells, Cultured | 1988 |
[Chemotherapy of non-small cell bronchial cancer with ifosfamide in combination with cisplatin, etoposide or vindesine].
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cisplatin; Drug Evaluation; Etoposide; Female; Follow-Up Studies; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Vindesine | 1988 |
Podophyllotoxins for brain metastases of small cell lung cancer.
Topics: Brain Neoplasms; Carcinoma, Small Cell; Etoposide; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Teniposide | 1988 |
Pharmacokinetic study of high dose etoposide infusion in patients with small cell lung cancer.
Topics: Carcinoma, Small Cell; Etoposide; Humans; Lung Neoplasms; Middle Aged | 1988 |
[Hepatotoxicity with etoposide-ifosfamide combination therapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Chemical and Drug Induced Liver Injury; Etoposide; Female; Humans; Ifosfamide; Liver Function Tests; Lung Neoplasms; Male; Middle Aged | 1988 |
Concurrent twice-daily radiotherapy plus platinum-etoposide chemotherapy for the treatment of limited small cell lung cancer: a preliminary report.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Radiation Injuries; Time Factors | 1988 |
Reduced short-term neuropsychological performance in patients with nonsmall-cell lung cancer treated with cisplatin and etoposide.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Lung Neoplasms; Memory; Middle Aged; Perception; Psychomotor Performance; Verbal Learning | 1988 |
Etoposide effective against small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Drug Evaluation; Etoposide; Humans; Lung Neoplasms | 1988 |
Etoposide (VP-16) and cisplatin: an effective treatment for relapse in small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Digestive System; Doxorubicin; Etoposide; Female; Humans; Kidney; Leukopenia; Lung Neoplasms; Male; Middle Aged; Thrombocytopenia; Vincristine | 1985 |
Multicenter Phase II trial of etoposide in refractory small cell lung cancer.
Topics: Carcinoma, Small Cell; Drug Evaluation; Etoposide; Female; Humans; Leukopenia; Lung Neoplasms; Male; Multi-Institutional Systems; Nausea; Podophyllotoxin; Vomiting | 1985 |
Extensive-stage small-cell bronchogenic carcinoma: intensive induction chemotherapy with high-dose cyclophosphamide plus high-dose etoposide.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pilot Projects; Podophyllotoxin; Thrombocytopenia; Vincristine | 1985 |
Late intensification in small-cell lung cancer: a phase I study of high doses of cyclophosphamide and etoposide with autologous bone marrow transplantation.
Topics: Adrenal Gland Neoplasms; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Carcinoma, Small Cell; Cyclophosphamide; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Podophyllotoxin | 1985 |
Intensive alternating chemotherapy regimen in small cell carcinoma of the lung.
Topics: Actuarial Analysis; Aged; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Brain Neoplasms; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Gastrointestinal Hemorrhage; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Thrombocytopenia; Vincristine | 1985 |
Probable cure of small cell carcinoma of the lung by etoposide.
Topics: Carcinoma, Small Cell; Etoposide; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Radiography; Smoking | 1985 |
The role of VP-16 in the treatment of small-cell lung cancer: studies of the West of Scotland Lung Cancer Group.
Topics: Carcinoma, Small Cell; Cyclophosphamide; Drug Resistance; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Verapamil | 1985 |
High-dose etoposide (VP-16) in small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Etoposide; Humans; Lung Neoplasms; Middle Aged; Podophyllotoxin | 1985 |
Single-dose etoposide in combination with vincristine and doxorubicin in the treatment of small-cell lung cancer (SCLC).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Middle Aged; Podophyllotoxin; Vincristine | 1985 |
Alternating combination chemotherapy regimens in small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Humans; Lung Neoplasms; Models, Biological; Vincristine | 1985 |
[Treatment of non-small-cell bronchial carcinoma with cisplatin, ifosfamide, vindesine and VP 16].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cisplatin; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Vinblastine; Vindesine | 1985 |
Relationship between myelosuppression and chemotherapeutic response in small cell bronchogenic carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Cyclophosphamide; Dactinomycin; Doxorubicin; Etoposide; Humans; Leucovorin; Lung Neoplasms; Methotrexate; Vincristine | 1985 |
Etoposide and cisplatin salvage chemotherapy for small cell lung cancer.
Topics: Aged; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Etoposide; Female; Humans; Injections, Intravenous; Leukocyte Count; Male; Middle Aged; Neoplasm Metastasis; Platelet Count; Podophyllotoxin | 1985 |
Bone marrow morphologic changes after combination chemotherapy including VP-16.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Erythrocytes; Etoposide; Female; Hematopoiesis; Humans; Lung Neoplasms; Male; Mitosis; Podophyllotoxin; Vincristine | 1985 |
Cisplatin and etoposide combination chemotherapy for refractory small cell carcinoma of the lung.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Lung Neoplasms; Male | 1985 |
Drug monitoring of etoposide (VP16-213). I. A combined method of liquid chromatography and mass spectrometry.
Topics: Californium; Carcinoma, Small Cell; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Computers; Etoposide; Half-Life; Humans; Kinetics; Lung Neoplasms; Mass Spectrometry; Podophyllotoxin | 1985 |
Three months' treatment with cyclophosphamide, VP-16-213 followed by methotrexate and thoracic radiotherapy for small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Etoposide; Female; Follow-Up Studies; Humans; Leukopenia; Lung Neoplasms; Male; Methotrexate; Middle Aged | 1985 |
Evaluation of drug efficacy in vitro using human small cell carcinoma of the lung spheroids.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cell Division; Cell Line; Cisplatin; Cytarabine; Doxorubicin; Drug Evaluation, Preclinical; Etoposide; Female; Humans; Lomustine; Lung Neoplasms; Mechlorethamine; Mice; Mice, Inbred Strains; Peritoneum; Tumor Stem Cell Assay | 1985 |
Intensive induction treatment of small cell bronchogenic carcinoma with cyclophosphamide, methotrexate, and etoposide.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Cyclophosphamide; Etoposide; Female; Humans; Leukocyte Count; Lung Neoplasms; Male; Methotrexate; Middle Aged; Platelet Count | 1985 |
Combination cyclophosphamide, Adriamycin, and vincristine rapidly alternating with combination cisplatin and VP-16 in treatment of small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoembryonic Antigen; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Radiation Injuries; Vincristine | 1985 |
[A phase II study of oral VP-16 in primary lung cancer].
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Anorexia; Capsules; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nausea; Podophyllotoxin | 1985 |
Three months treatment with chemotherapy and radiotherapy for small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Etoposide; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged | 1985 |
The effect of food and concurrent chemotherapy on the bioavailability of oral etoposide.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Carcinoma, Small Cell; Drug Interactions; Etoposide; Food; Humans; Kinetics; Lung Neoplasms; Podophyllotoxin | 1985 |
[A phase II study of NK171 (etoposide)].
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Alopecia; Anorexia; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Infusions, Parenteral; Leukopenia; Lung Neoplasms; Male; Middle Aged; Nausea; Podophyllotoxin | 1985 |
High-dose cyclophosphamide and VP 16 as late dosage intensification therapy for small cell carcinoma of lung.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carcinoma, Small Cell; Cyclophosphamide; Etoposide; Follow-Up Studies; Humans; Lung Neoplasms; Podophyllotoxin | 1985 |
Acute nonlymphocytic leukemia, preleukemia, and solid tumors following intensive chemotherapy of small cell carcinoma of the lung.
Topics: Acute Disease; Carcinoma, Small Cell; Chromosome Aberrations; Chromosome Disorders; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Leukemia; Lomustine; Lung Neoplasms; Male; Methotrexate; Preleukemia; Risk; Vincristine | 1985 |
[A phase II study of etoposide (NK 171) in small cell lung cancer--comparison of results between intravenous administration and oral administration].
Topics: Administration, Oral; Adult; Aged; Alopecia; Anorexia; Carcinoma, Small Cell; Drug Evaluation; Etoposide; Fatigue; Female; Humans; Infusions, Parenteral; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1985 |
Variable bioavailability following repeated oral doses of etoposide.
Topics: Adult; Biological Availability; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Humans; Kinetics; Lung Neoplasms; Mesothelioma; Podophyllotoxin; Time Factors | 1985 |
Cisplatin and etoposide alternating with vincristine, doxorubicin and cyclophosphamide in patients with small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Hormones, Ectopic; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Vincristine | 1985 |
[A phase II study of etoposide (VP-16) injection in primary lung cancer by cooperative study group].
Topics: Adenocarcinoma; Adult; Aged; Alopecia; Anorexia; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Injections; Lung Neoplasms; Male; Middle Aged; Nausea; Podophyllotoxin | 1986 |
Carboplatin (JM8) as a single agent and in combination in the treatment of small cell lung cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Etoposide; Humans; Lung Neoplasms; Organoplatinum Compounds | 1985 |
Cyclic alternating chemotherapy for small cell carcinoma of the lung.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Mitomycins; Nausea; Prospective Studies; Vincristine; Vomiting | 1985 |
Pharmacokinetic evaluation of increasing dosages of etoposide in a chronic hemodialysis patient.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chromatography, High Pressure Liquid; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Kidney Failure, Chronic; Kinetics; Lung Neoplasms; Male; Mathematics; Middle Aged; Podophyllotoxin; Renal Dialysis | 1985 |
The effect of dose on the bioavailability of oral etoposide.
Topics: Administration, Oral; Adult; Biological Availability; Carcinoma, Small Cell; Chromatography, High Pressure Liquid; Etoposide; Half-Life; Humans; Kinetics; Mesothelioma; Podophyllotoxin; Random Allocation | 1986 |
High-dose cyclophosphamide and high-dose VP 16-213 for recurrent or refractory small cell lung cancer. A phase II study.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local | 1985 |
Neurologic dysfunction in patients treated for small cell carcinoma of the lung: a clinical and radiological study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Diseases; Brain Neoplasms; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lomustine; Lung Neoplasms; Male; Middle Aged; Mitomycin; Mitomycins; Procarbazine; Vincristine | 1986 |
[A phase II study of intravenous VP-16-213 in small cell and non-small cell carcinoma of the lung].
Topics: Adult; Aged; Alopecia; Carcinoma, Small Cell; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Infusions, Parenteral; Lung Neoplasms; Male; Middle Aged; Nausea; Podophyllotoxin | 1986 |
[Phase II study of etoposide in patients with lung cancer, with special reference to small cell carcinoma].
Topics: Adenocarcinoma; Aged; Carcinoma, Small Cell; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1986 |
[Phase II study of VP-16 in patients with primary bronchogenic carcinoma, with special reference to small cell carcinoma--a multi-institutional cooperative study].
Topics: Administration, Oral; Aged; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1986 |
Etoposide (VP-16) and cisplatin in previously treated small-cell lung cancer: clinical trial and in vitro correlates.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Evaluation; Drug Resistance; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Tumor Stem Cell Assay | 1986 |
[Combination chemotherapy with etoposide, mitomycin C, and cyclophosphamide in advanced non-small cell lung cancer].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Mitomycin; Mitomycins | 1986 |
Cisplatin, etoposide, and mitomycin in the treatment of non-small cell carcinoma of the lung. A pilot study.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cisplatin; Drug Evaluation; Etoposide; Humans; Lung Neoplasms; Middle Aged; Mitomycins; Pilot Projects | 1986 |
DNA breakage in human lung carcinoma cells and nuclei that are naturally sensitive or resistant to etoposide and teniposide.
Topics: Adenocarcinoma; Adenosine Triphosphate; Carcinoma, Small Cell; Cell Division; Cell Nucleus; Cells, Cultured; DNA; DNA, Single-Stranded; Drug Resistance; Etoposide; Humans; Intercalating Agents; Lung Neoplasms; Podophyllotoxin; Teniposide; Topoisomerase II Inhibitors | 1986 |
No response improvement after sequential chemotherapy for small cell lung cancer.
Topics: Adult; Aged; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Daunorubicin; Drug Evaluation; Etoposide; Female; Humans; Lomustine; Lung Neoplasms; Male; Middle Aged; Prednisone; Time Factors; Vincristine | 1986 |
High-dose etoposide with autologous bone marrow transplantation as initial treatment of small cell lung cancer--a negative report.
Topics: Bone Marrow Diseases; Bone Marrow Transplantation; Carcinoma, Small Cell; Combined Modality Therapy; Etoposide; Humans; Lung Neoplasms; Middle Aged; Mouth Mucosa; Podophyllotoxin; Stomatitis; Transplantation, Autologous | 1986 |
Etoposide, cisplatin and doxorubicin in patients with small cell lung cancer: tumor response and long term survival.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Etoposide; Female; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Thrombocytopenia | 1986 |
Etoposide: a pharmacokinetic profile including an assessment of bioavailability.
Topics: Administration, Oral; Biological Availability; Carcinoma; Carcinoma, Small Cell; Etoposide; Female; Hodgkin Disease; Humans; Injections, Intravenous; Kinetics; Lung Neoplasms; Lymphoma; Male; Neoplasms; Podophyllotoxin | 1986 |
First-line therapy with VP-16 and cisplatin for small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Lung Neoplasms; Remission Induction | 1986 |
Alternating chemotherapy and thoracic radiotherapy with concurrent cisplatin-etoposide for limited-stage small-cell carcinoma of the lung.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Prognosis; Radiotherapy; Vincristine | 1986 |
Concurrent chemotherapy and radiotherapy for limited small-cell carcinoma of the lung: a Southwest Oncology Group Study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Lung Neoplasms; Pilot Projects; Prognosis; Radiotherapy; Remission Induction | 1986 |
High-dose pilot studies in extensive-stage small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Etoposide; Humans; Lung Neoplasms; Pilot Projects; Remission Induction | 1986 |
[A combination chemotherapy of cisplatin and etoposide in small cell lung cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged | 1986 |
Short duration combination chemotherapy in the treatment of small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Methotrexate; Vincristine | 1986 |
Five-year survival in treated stage I and II small cell carcinoma of the lung.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lomustine; Lung Neoplasms; Neoplasm Staging; Pneumonectomy; Postoperative Care; Vincristine | 1986 |
[Treatment of microcytic carcinoma of the lung with vincristine, adriamycin, cyclophosphamide and VP-16].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Etoposide; Female; Humans; Lung Neoplasms; Male; Vincristine | 1986 |
Long-term effects of intravenous hyperalimentation administered during intensive chemotherapy for small cell bronchogenic carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Hypersensitivity, Delayed; Ifosfamide; Lung Neoplasms; Male; Methotrexate; Middle Aged; Parenteral Nutrition, Total; Procarbazine; Prognosis; Vincristine | 1987 |
Adriamycin, cyclophosphamide and etoposide (ACE) in the treatment of small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged | 1986 |
Small cell carcinoma of the lung: influence of age on treatment outcome.
Topics: Actuarial Analysis; Adult; Aged; Aging; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Heart Diseases; Hematologic Diseases; Humans; Lung Neoplasms; Middle Aged | 1987 |
Experience with ifosfamide combinations (etoposide or DDP) in non-small cell lung cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cisplatin; Drug Evaluation; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged | 1986 |
Cytogenetic effects of multiagent chemotherapy on the peripheral lymphocytes of patients with small cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chromosome Aberrations; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Lymphocytes; Male; Middle Aged; Sister Chromatid Exchange; Vincristine | 1986 |
Cyclophosphamide, etoposide, and infusion cisplatin in refractory small cell lung cancer. A preliminary report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Vincristine | 1987 |
High-dose etoposide therapy for extensive small cell lung cancer: a Cancer and Leukemia Group B Study.
Topics: Aged; Carcinoma, Small Cell; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged | 1987 |
The role of surgery in the management of selected patients with small-cell carcinoma of the lung.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Evaluation Studies as Topic; Female; Follow-Up Studies; Humans; Lung Neoplasms; Lymph Node Excision; Male; Middle Aged | 1987 |
High-dose induction chemotherapy with cyclophosphamide, etoposide, and cisplatin for extensive-stage small-cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Dose-Response Relationship, Drug; Etoposide; Fever; Humans; Infections; Leukopenia; Lung Neoplasms; Middle Aged; Thrombocytopenia | 1987 |
[A cisplatin and etoposide combination in small cell anaplastic carcinoma of the lung].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Etoposide; Humans; Lung Neoplasms | 1987 |
High-dose etoposide for central nervous system metastases of small cell lung cancer. Preliminary results.
Topics: Adult; Aged; Brain Neoplasms; Carcinoma, Small Cell; Etoposide; Humans; Lung Neoplasms; Middle Aged | 1987 |
Etoposide for small cell lung cancer.
Topics: Carcinoma, Small Cell; Etoposide; Humans; Lung Neoplasms | 1987 |
Intensive chemotherapy in small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Etoposide; Humans; Lung Neoplasms | 1986 |
Improved local control of thoracic disease in small cell lung cancer with higher dose thoracic irradiation and cyclic chemotherapy.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Etoposide; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Radiotherapy Dosage | 1987 |
Treatment of small cell lung cancer by pneumonectomy and single course high dose chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Etoposide; Humans; Lung Neoplasms; Male; Pneumonectomy | 1987 |
Etoposide combination therapy for small cell carcinoma of the lung.
Topics: Adult; Aged; Carcinoma, Small Cell; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Vincristine | 1987 |