Page last updated: 2024-08-23

etoposide and Carcinoma, Hepatocellular

etoposide has been researched along with Carcinoma, Hepatocellular in 102 studies

Research

Studies (102)

Timeframe	Studies, this research(%)	All Research%
pre-1990	15 (14.71)	18.7374
1990's	27 (26.47)	18.2507
2000's	30 (29.41)	29.6817
2010's	23 (22.55)	24.3611
2020's	7 (6.86)	2.80

Authors

Authors	Studies
Cheung, CC; Fung, KP; Lai, PB; Lee, WY; Liu, KW; Wong, J; Yeung, JH	1
Chen, JT; Ma, R; Mu, Q; Sun, SC; Xu, XL; Zhu, XF	1
Deng, X; Lei, F; Li, Z; Liu, D; Luo, T; Shi, T; Wang, Z; Wen, H; Yang, X; Zhang, H; Zhao, Q	1
Labbozzetta, M; Notarbartolo, M; Occhipinti, C; Poma, P; Sajeva, M	1
Kim, KD; Lee, KY; Shin, WY	1
Cao, J; Cao, M; Du, L; Feng, J; Jin, J; Li, X; Liang, S; Shen, B; Wang, H; Wang, J; Yu, J; Zhang, J; Zhang, Y; Zhou, Y; Zhu, T	1
Han, Y; Li, L; Sun, H	1
Czauderna, C; Galle, PR; Heil, E; Heinrich, B; Heinrich, S; Kloeckner, R; Koch, S; Marquardt, JU; Philippe P Diggs, L; Schmidtmann, I; Sprinzl, M; Weinmann, A; Wörns, MA	1
Chen, P; Liu, H; Liu, Y; Qian, C; Qu, Y; Tang, L; Xin, Y; Xu, Y	1
Bian, J; Cai, J; Luo, S; Tsend-Ayush, A; Wen, J; Yao, J; Yin, L; Yuan, Z; Zhou, J; Zhu, X	1
Chen, CC; Chen, CY; Chou, LF; Ho, JY; Hsueh, C; Ueng, SH; Wang, TH; Yeh, CT	1
Cen, P; Dinh, B; Mays, SR; Patel, AB; Rios, A	1
Li, QG; Tong, Y; Xia, Q; Xing, TY; Zhang, JJ; Zhang, M	1
Calabrese, D; Dietsche, T; Dill, MT; Duong, FH; Heim, MH; Ketterer, S; Makowska, Z; Matter, MS; Terracciano, L	1
Cui, Z; Jiao, T; Li, Z; Liu, N; Peng, J; Ye, X; Zhang, J	1
Feng, Y; Man, K; Tsao, SW; Wang, N; Zhang, Z; Zhu, M	1
Cheong, J; Jung, HU; Kim, HY; Park, BS; Yoo, KS; Yoo, SH; Yoo, YH; Yun, I	1
Cao, J; Ding, L; Liang, G; Luo, P; Ma, S; Shi, S; Wang, D; Weng, Q; Yao, Z; Yuan, C; Zhu, H; Zhuang, K	1
An, L; Chen, Y; Feng, F; Gao, X; Lu, Y; Qu, J; Sun, H; Wang, C; Wang, F; Yang, Y; Zeng, Z; Zhang, C	1
Benhamouche, S; Di Martino, J; Javary, J; Neaud, V; Raymond, AA; Rosenbaum, J	1
Min, J; Wang, Q; Xu, Z; Yang, M; Zhang, AQ	1
Cao, Y; Feng, F; Hou, MX; Jia, H; Jiang, QY; Ma, HD; Sun, HW; Wang, T; Yang, Q; Yang, YP	1
Chen, M; Han, S; Hui, L; Lan, S; Li, D; Li, L; Xu, X; Yang, Z; Yue, L	1
Fang, JH; Jiang, W; Liang, C; Qiu, FE; Shen, Y; Xiong, XD; Zhuang, SM	1
Britschgi, A; Britschgi, C; Fey, MF; Helin, K; Jenal, M; Leprince, D; Roh, V; Tobler, A; Trinh, E; Tschan, MP; Vorburger, SA	1
Chiang, PC; Guh, JH; Hsu, JL	1
Chen, GG; Lai, PB; Song, G; Yun, JP	1
Cho, SJ; Choi, JS; Kim, HY; Lee, SK; Lee, WH; Park, BD; Park, JH; Surh, YJ	1
Ai, ZL; Gao, C; Jin, B; Lv, DC; Ma, DL; Shu, XM; Wu, CL; Xie, BS; Yao, SK; Zhao, HC; Zhuo, DX	1
Chen, T; Fan, J; Gao, Q; Gu, J; He, X; Hu, X; Hui, X; Li, J; Wan, D; Wang, T; Wang, X; Yan, M; Yao, M; Zhao, Y	1
Abdulghani, J; Allen, JE; Dicker, DT; Dolloff, NG; El-Deiry, WS; Gallant, JN; Hong, B; Katz, SI; Navaraj, A; Smith, CD; Wang, W	1
Bollag, WB; Liu, F; Liu, K; Liu, Q; Robertson, K; Wu, P; Yang, D	1
Choi, YH; Kwon, TK; Lee, JS; Oh, JS; Park, BS; Park, C; Song, YS; Yoo, SH; Yoo, YH; Yoon, YG	1
Jaiswal, AK; Niture, SK	1
Beloqui, O; Bilbao, I; Herrero, JI; Prieto, J; Quiroga, J; Rios, R; Sangro, B	1
Cao, WJ; Huang, W; Li, DJ; Liu, WL; Zhang, YZ	1
Achanzar, WE; Mori, M; Nagamine, T; Qu, W; Shimoda, R; Takagi, H; Waalkes, MP	1
Lund, P; Niketeghad, F; Schirmacher, P; Schubert, D	1
Choi, SH; Hong, SY; Hyung, WJ; Jung, HC; Kim, KS; Lee, MH; Noh, SH; Roh, JK	1
Horb, ME; Li, WC; Slack, JM; Tosh, D	1
Beurel, E; Blivet-Van Eggelpoël, MJ; Cadoret, A; Capeau, J; Desbois-Mouthon, C; Kornprobst, M	1
Amemiya, H; Asakawa, M; Fujii, H; Kono, H; Maki, A; Matsuda, M; Suzuki, T	1
Dai, J; Guo, Y; Jin, J; Shi, M; Wang, R; Wu, M; Zhang, X; Zhao, J	1
Aoyagi, S; Fujishita, M; Hisaka, T; Horiuchi, H; Ishikawa, H; Kawashima, Y; Kinoshita, H; Nokita, H; Shirouzu, K; Uchida, S	1
Bjeldanes, LF; Firestone, GL; Gong, Y	1
Cosse, JP; Michiels, C; Ninane, N; Piret, JP; Raes, M	1
Mistafa, O; Roudier, E; Stenius, U	1
Ling, MT; Wang, X; Wong, YC; Zhang, X	1
Du, SY; Hsu, YW; Jiang, MC; Li, LT; Liao, CF; Lin, CC; Lin, CY; Luo, SF	1
Frank, H; Fuchs, J; Heitmann, H; Herberts, T; Ruck, P; Seitz, G; Warmann, SW	1
Imai, M; Ishikawa, T; Kamimura, H; Kamimura, T; Ohta, H; Seki, K; Togashi, T; Tsuchiya, A; Watanabe, K; Yoshida, T	1
An, L; Han, Y; Miao, R; Wang, Q; Yang, J	1
Chang, HM; Kang, YK; Kim, KM; Kim, MK; Kim, TW; Lee, JL; Lee, JS; Lee, SS; Ryu, MH; Sym, SJ	1
Hu, K; Shao, ZY; Shen, DM; Wu, F; Zhai, BJ; Zhao, CL	1
Chau, DK; Chen, GG; Lai, PB; Miao, J; Song, G	1
Chang, FY; Chao, Y; Lee, RC; Lee, SD; Lee, WP; Li, CP; Whang-Peng, J; Yen, SH; Yuan, JN	1
Melia, WM; Westaby, D; Williams, R	1
Brunner, KW; Cavalli, F; Goldhirsch, A; Joss, R; Ryssel, HJ; Sonntag, RW	1
Cavalli, F; Goldhirsch, A; Hansen, HH; Renard, J; Rozencweig, M	1
Jungi, WF	1
Johnson, PJ; Melia, WM; Williams, R	1
Kaneko, Y; Tsukamoto, A	1
Abdel-Warith, A; Abdulkareem, M; Amin, T; Ayoub, A; Ezzat, A; Fadda, M; Kagevi, I; Sieck, J; Wierzbicki, R; Yazigi, A	1
Ikami, I; Kanehira, J; Kimura, T; Nishi, N; Saito, Y; Sasaki, T; Takahashi, S; Takekawa, SD; Tarusawa, K; Yodono, H	1
Gohda, E; Hamasaki, K; Namba, M; Orita, K; Seshimo, K	1
Aiba, K; Dobashi, F; Fujii, T; Funakoshi, S; Hirano, A; Inamoto, Y; Kuraishi, Y; Ogihara, A; Tada, N; Yamada, T	1
Bailey, CC; Giles, GR; Heney, D; Lewis, IJ; Lockwood, L	1
Chen, BR; Chen, DS; Chen, YC; Cheng, AL; Chuang, SE; Yeh, KH	1
Deguchi, S; Fujita, M; Honda, K; Kikuchi, T; Miyata, A	1
Aoki, T; Dohno, K; Gotoh, M; Higaki, N; Kishimoto, S; Monden, M; Okuyama, M; Osato, H; Sakon, M; Shimizu, J; Sugimoto, K; Takeda, H; Taniguchi, K; Umeshita, K; Yamada, T	1
Aita, P; Boiocchi, M; Robieux, I; Sorio, R; Toffoli, G	1
Adjei, PN; Gores, GJ; Kaufmann, SH; Leung, WY; Mao, F	1
Ishimura, H	1
Cheng, AL; Chou, YY; Hsu, HC	1
Bertulezzi, G; Bobbio-Pallavicini, E; Civelli, L; Moroni, M; Nastasi, G; Porta, C; Pugliese, P	1
Aita, P; Boiocchi, M; Cannizzaro, R; Colussi, AM; Corona, G; Robieux, I; Sorio, R; Toffoli, G; Tumolo, S	1
Aita, P; Bearz, A; Boiocchi, M; Colussi, AM; Corona, G; Sartor, F; Sorio, R; Toffoli, G	1
Lash, LH; Mathieu, P; Okafor, C; Putt, DA; Reiners, JJ	1
Barajas, MA; Peng, D; Prieto, J; Qian, C; Sun, Y	1
Ikeda, J; Takayasu, Y; Yamamoto, S	1
Takayasu, Y	1
Brunner, KW; Cavalli, F; Sonntag, RW	1
Brunner, KW; Cavalli, F; Gerber, A; Ryssel, HJ; Sonntag, RW; Tschopp, L	1
Ikami, I; Kanehira, J; Noda, H; Sasaki, T; Shibutani, K; Shinohara, A; Takahashi, S; Takekawa, D; Tarusawa, K; Yodono, H	1
Bellman, SC; Brock, PR; Pritchard, J; Yeomans, EC	1
Midorikawa, H; Saito, Y; Sasaki, T; Takekawa, SD; Tarusawa, K; Yodono, H	1
Aoki, K; Nose, H; Okada, S; Okazaki, N; Yoshimori, M	1
Gotoda, A; Kamiyama, T; Matsuoka, S; Nagabuchi, E; Nakajima, Y; Saito, M; Uchino, J; Une, Y	1
Furukawa, H; Hara, T; Hoshino, K; Taniguchi, T	1
Fujita, M; Imaoka, S; Inoue, A; Ishiguro, S; Kasugai, H; Kojima, J; Okuda, S; Sasaki, Y; Shibata, K	1
Hayashi, K; Ito, T; Sugino, N; Yakabe, A; Yamashita, S	1
Akimura, R; Fujii, N; Ikami, I; Kanehira, J; Kimura, T; Midorikawa, H; Nakamura, Y; Sasaki, T; Tarusawa, K; Yodono, H	1
Fujino, H; Tagawa, K; Unuma, T; Yasuda, H	1
Izumi, R; Kobayashi, K; Matsui, O; Miyazaki, I; Shimizu, K; Watanabe, T	1
Hashimoto, N; Hayashi, S; Kanda, Y; Miki, M; Oda, H; Okazaki, N; Sasagawa, Y; Yoshida, T; Yoshino, M	1
Anas, N; Cairo, MS; Sender, L; Siegel, S	1
Kanehira, J; Kimura, T; Nakamura, Y; Nishi, N; Saito, Y; Sasaki, T; Takahashi, S; Takekawa, S; Tarusawa, K; Yodono, H	1
Kimura, K; Niitani, H; Yamada, K	1
Bennett, M; Buamah, PK; James, OF; Lendrum, R; McArdle, P	1
Bonardi, G; Calciati, A; Donadio, M; Giaccone, G; Leria, G	1
Leung, N; Li, A; Li, M; Martin, C; Mok, SD; Shiu, W; Zacharia, A	1
Furusawa, A; Hattori, N; Hirai, N; Izumi, R; Kato, Y; Kobayashi, K; Matsui, O; Shimoda, A; Tanaka, N; Unoura, M	1

Reviews

3 review(s) available for etoposide and Carcinoma, Hepatocellular

Article	Year
Mixed Primary Hepatocellular Carcinoma and Hepatic Neuroendocrine Carcinoma: Case Report and Literature Review. Medicina (Kaunas, Lithuania), 2023, Feb-20, Volume: 59, Issue:2 Topics: Carcinoma, Hepatocellular; Carcinoma, Neuroendocrine; Etoposide; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local	2023
[Etoposide. A new highly effective cytostatic agent in anaplastic small-cell bronchial carcinoma, other solid tumors and hemoblastoses]. Deutsche medizinische Wochenschrift (1946), 1981, Aug-28, Volume: 106, Issue:35 Topics: Bronchial Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Small Cell; Cell Division; Choriocarcinoma; Etoposide; Female; Humans; Leukemia; Liver Neoplasms; Lung Neoplasms; Male; Ovarian Neoplasms; Podophyllotoxin; Pregnancy; Testicular Neoplasms; Uterine Neoplasms	1981
[Hepatic arterial infusion chemotherapy for hepatocellular carcinoma by EEP regimen]. Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59 Suppl 6 Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Catheters, Indwelling; Cisplatin; Drug Administration Schedule; Epirubicin; Etoposide; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Treatment Outcome	2001

Trials

9 trial(s) available for etoposide and Carcinoma, Hepatocellular

Article	Year
Improved survival for hepatocellular carcinoma with portal vein tumor thrombosis treated by intra-arterial chemotherapy combining etoposide, carboplatin, epirubicin and pharmacokinetic modulating chemotherapy by 5-FU and enteric-coated tegafur/uracil: a p World journal of gastroenterology, 2007, Nov-07, Volume: 13, Issue:41 Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Hepatocellular; Chemotherapy, Cancer, Regional Perfusion; Epirubicin; Etoposide; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Kaplan-Meier Estimate; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Pilot Projects; Portal Vein; Prospective Studies; Severity of Illness Index; Tablets, Enteric-Coated; Tegafur; Time Factors; Treatment Outcome; Uracil; Venous Thrombosis	2007
Chemotherapy with etoposide, doxorubicin, cisplatin, 5-fluorouracil, and leucovorin for patients with advanced hepatocellular carcinoma. Medical oncology (Northwood, London, England), 2008, Volume: 25, Issue:2 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Doxorubicin; Etoposide; Female; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Male; Middle Aged	2008
Induction of remission in hepatocellular carcinoma. A comparison of VP 16 with adriamycin. Cancer, 1983, Jan-15, Volume: 51, Issue:2 Topics: Adolescent; Adult; Aged; Carcinoma, Hepatocellular; Doxorubicin; Etoposide; Female; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pilot Projects; Podophyllotoxin; Prognosis; Random Allocation	1983
Phase II trial of chronic daily VP-16 administration in unresectable hepatocellular carcinoma (HCC). Annals of oncology : official journal of the European Society for Medical Oncology, 1994, Volume: 5, Issue:5 Topics: Administration, Oral; Adult; Aged; Carcinoma, Hepatocellular; Drug Administration Schedule; Etoposide; Female; Humans; Liver Neoplasms; Male; Middle Aged	1994
Chronic oral etoposide and tamoxifen in the treatment of far-advanced hepatocellular carcinoma. Cancer, 1996, Mar-01, Volume: 77, Issue:5 Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Drug Administration Schedule; Etoposide; Female; Humans; Liver Neoplasms; Male; Middle Aged; Prospective Studies; Tamoxifen	1996
Epirubicin and etoposide combination chemotherapy to treat hepatocellular carcinoma patients: a phase II study. European journal of cancer (Oxford, England : 1990), 1997, Volume: 33, Issue:11 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Epirubicin; Etoposide; Female; Follow-Up Studies; Humans; Liver Neoplasms; Male; Middle Aged; Survival Analysis; Survival Rate; Treatment Outcome	1997
Pharmacokinetic interaction between etoposide and tamoxifen in patients with hepatocellular carcinoma. Anti-cancer drugs, 1999, Volume: 10, Issue:9 Topics: Aged; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carcinoma, Hepatocellular; Drug Interactions; Etoposide; Female; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Protein Binding; Tamoxifen; Time Factors	1999
Clinical trial of continuous infusion verapamil, bolus vinblastine, and continuous infusion VP-16 in drug-resistant pediatric tumors. Cancer research, 1989, Feb-15, Volume: 49, Issue:4 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Child; Child, Preschool; Clinical Trials as Topic; Etoposide; Humans; Infusions, Intravenous; Leukemia; Liver Neoplasms; Neuroblastoma; Verapamil; Vinblastine	1989
[Phase I clinical study of NK 171 (etoposide)]. Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:4 Topics: Administration, Oral; Adult; Aged; Carcinoma, Hepatocellular; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Infusions, Parenteral; Liver Neoplasms; Lung Neoplasms; Lymphoma; Male; Middle Aged; Neoplasms; Podophyllotoxin	1985

Other Studies

90 other study(ies) available for etoposide and Carcinoma, Hepatocellular

Article	Year
Cytotoxic effects of tanshinones from Salvia miltiorrhiza on doxorubicin-resistant human liver cancer cells. Journal of natural products, 2010, May-28, Volume: 73, Issue:5 Topics: Abietanes; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Doxorubicin; Drug Resistance, Neoplasm; Humans; Models, Biological; Molecular Structure; Phenanthrenes; Plants, Medicinal; Salvia miltiorrhiza	2010
Synthesis and biological evaluation of cyclopeptide GG-8-6 and its analogues as anti-hepatocellular carcinoma agents. Bioorganic & medicinal chemistry, 2018, 02-01, Volume: 26, Issue:3 Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Female; G2 Phase Cell Cycle Checkpoints; Hep G2 Cells; Humans; Liver Neoplasms; M Phase Cell Cycle Checkpoints; Mice; Mice, Inbred BALB C; Mice, Nude; Peptides, Cyclic; Protein Structure, Tertiary; Structure-Activity Relationship; Transplantation, Heterologous	2018
Design, synthesis and anti-hepatocellular carcinoma activity of 3-arylisoquinoline alkaloids. European journal of medicinal chemistry, 2022, Jan-15, Volume: 228 Topics: Alkaloids; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Isoquinolines; Liver Neoplasms; Molecular Structure; Structure-Activity Relationship	2022
Antitumor Effect of Molecules (Basel, Switzerland), 2022, Jun-29, Volume: 27, Issue:13 Topics: Antineoplastic Agents; Boraginaceae; Carcinoma, Hepatocellular; DNA Topoisomerases, Type II; Etoposide; Humans; Leukemia, Myeloid, Acute; Liver Neoplasms; Naphthoquinones; Oils, Volatile; Reactive Oxygen Species; Topoisomerase II Inhibitors	2022
Components of the JNK-MAPK pathway play distinct roles in hepatocellular carcinoma. Journal of cancer research and clinical oncology, 2023, Volume: 149, Issue:19 Topics: Anisomycin; Apoptosis; Carcinoma, Hepatocellular; Etoposide; Humans; JNK Mitogen-Activated Protein Kinases; Liver Neoplasms; MAP Kinase Kinase 7; Tumor Necrosis Factor-alpha	2023
Computed Tomography and Magnetic Resonance Imaging in the Diagnosis of Primary Neuroendocrine Tumors of the Liver. World neurosurgery, 2020, Volume: 138 Topics: Ablation Techniques; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Carcinoma, Neuroendocrine; Chemoembolization, Therapeutic; Cisplatin; Etoposide; Female; Hepatectomy; Humans; Liver Neoplasms; Lymph Nodes; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Grading; Neuroendocrine Tumors; Octreotide; Tomography, X-Ray Computed	2020
Validation of prognostic accuracy of MESH, HKLC, and BCLC classifications in a large German cohort of hepatocellular carcinoma patients. United European gastroenterology journal, 2020, Volume: 8, Issue:4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Biopsy; Carcinoma, Hepatocellular; Etoposide; Female; Germany; Humans; Ifosfamide; Kaplan-Meier Estimate; Liver; Liver Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Mitoxantrone; Neoplasm Staging; Predictive Value of Tests; Prognosis; Retrospective Studies; Risk Assessment; ROC Curve; Tomography, X-Ray Computed; Young Adult	2020
Dual-modified albumin-polymer nanocomplexes with enhanced in vivo stability for hepatocellular carcinoma therapy. Colloids and surfaces. B, Biointerfaces, 2021, Volume: 201 Topics: Albumins; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Etoposide; Liver Neoplasms; Mice; Nanoparticles; Polymers	2021
Glycyrrhetinic acid-modified TPGS polymeric micelles for hepatocellular carcinoma-targeted therapy. International journal of pharmaceutics, 2017, Aug-30, Volume: 529, Issue:1-2 Topics: Carcinoma, Hepatocellular; Drug Carriers; Etoposide; Glycyrrhetinic Acid; Humans; Micelles; Vitamin E	2017
Corylin increases the sensitivity of hepatocellular carcinoma cells to chemotherapy through long noncoding RNA RAD51-AS1-mediated inhibition of DNA repair. Cell death & disease, 2018, 05-01, Volume: 9, Issue:5 Topics: Carcinoma, Hepatocellular; Cell Movement; Cell Proliferation; DNA Repair; Etoposide; Flavonoids; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; RNA, Long Noncoding; RNA, Neoplasm	2018
Dramatic response of nivolumab-associated psoriasiform dermatitis to etoposide. European journal of cancer (Oxford, England : 1990), 2019, Volume: 107 Topics: Antineoplastic Agents, Immunological; Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Dermatitis; Etoposide; Humans; Liver Neoplasms; Male; Middle Aged; Nivolumab; Prognosis; Psoriasis	2019
HIF1 regulates WSB-1 expression to promote hypoxia-induced chemoresistance in hepatocellular carcinoma cells. FEBS letters, 2013, Aug-19, Volume: 587, Issue:16 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Carrier Proteins; Cell Hypoxia; DNA Damage; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Intracellular Signaling Peptides and Proteins; Liver Neoplasms; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Proteins; RNA Interference; RNA, Small Interfering; Tetrazolium Salts; Thiazoles	2013
Protein phosphatase 2A promotes hepatocellular carcinogenesis in the diethylnitrosamine mouse model through inhibition of p53. Carcinogenesis, 2014, Volume: 35, Issue:1 Topics: Animals; Biopsy; Carcinoma, Hepatocellular; Diethylnitrosamine; Disease Models, Animal; Etoposide; Gene Expression Regulation, Enzymologic; Hepacivirus; Hepatitis B, Chronic; Humans; Liver Neoplasms; Mice; Mice, Inbred C57BL; Mice, Transgenic; Organophosphorus Compounds; Phosphorylation; Protein Phosphatase 2; Tumor Suppressor Protein p53	2014
Hepatitis B virus inhibits apoptosis of hepatoma cells by sponging the MicroRNA 15a/16 cluster. Journal of virology, 2013, Volume: 87, Issue:24 Topics: Adult; Aged; Animals; Antiviral Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Down-Regulation; Etoposide; Female; Hepatitis B virus; Host-Pathogen Interactions; Humans; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; MicroRNAs; Middle Aged; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; RNA, Viral	2013
MiR-23a-mediated inhibition of topoisomerase 1 expression potentiates cell response to etoposide in human hepatocellular carcinoma. Molecular cancer, 2013, Oct-08, Volume: 12, Issue:1 Topics: 3' Untranslated Regions; Animals; Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; Base Sequence; Binding Sites; Carcinoma, Hepatocellular; Cell Line, Tumor; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Resistance, Neoplasm; Etoposide; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Poly-ADP-Ribose Binding Proteins; RNA Interference; Tumor Burden; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays	2013
Sorafenib overcomes the chemoresistance in HBx-expressing hepatocellular carcinoma cells through down-regulation of HBx protein stability and suppresses HBV gene expression. Cancer letters, 2014, Dec-01, Volume: 355, Issue:1 Topics: Antineoplastic Agents; Apoptosis; Autophagy; Carcinoma, Hepatocellular; Cisplatin; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Viral; Hep G2 Cells; Hepatitis B virus; Humans; Interferon-alpha; Liver Neoplasms; Niacinamide; Phenylurea Compounds; Promoter Regions, Genetic; Proteasome Endopeptidase Complex; Protein Stability; Sorafenib; Trans-Activators; Transfection; Viral Regulatory and Accessory Proteins	2014
Resistance of SMMC-7721 hepatoma cells to etoposide in hypoxia is reversed by VEGF inhibitor. Molecular medicine reports, 2015, Volume: 11, Issue:5 Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Hypoxia; Cell Line, Tumor; Drug Resistance, Neoplasm; Etoposide; Extracellular Signal-Regulated MAP Kinases; Humans; Hypoxia; Liver Neoplasms; NF-kappa B; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Vascular Endothelial Growth Factor A	2015
MiRNA153 Reduces Effects of Chemotherapeutic Agents or Small Molecular Kinase Inhibitor in HCC Cells. Current cancer drug targets, 2015, Volume: 15, Issue:3 Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Etoposide; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; MicroRNAs; Molecular Targeted Therapy; Niacinamide; Paclitaxel; Phenylurea Compounds; Protein Kinase Inhibitors; PTEN Phosphohydrolase; Sorafenib	2015
Reptin regulates DNA double strand breaks repair in human hepatocellular carcinoma. PloS one, 2015, Volume: 10, Issue:4 Topics: Antineoplastic Agents, Phytogenic; Ataxia Telangiectasia Mutated Proteins; ATPases Associated with Diverse Cellular Activities; Blotting, Western; Carcinoma, Hepatocellular; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Comet Assay; DNA Breaks, Double-Stranded; DNA Helicases; DNA Repair; DNA-Activated Protein Kinase; Etoposide; Gamma Rays; Histones; Humans; Liver Neoplasms; Microscopy, Confocal; Nuclear Proteins; Phosphorylation; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference	2015
A hyposensitive anticancer drug induces higher surface expression and release of heat shock proteins in a human hepatocellular carcinoma cell line. Molecular medicine reports, 2015, Volume: 12, Issue:2 Topics: Antineoplastic Agents; Apoptosis; Carboplatin; Carcinoma, Hepatocellular; Enzyme-Linked Immunosorbent Assay; Etoposide; Gene Expression Regulation, Neoplastic; Heat-Shock Proteins; Hep G2 Cells; HSP70 Heat-Shock Proteins; Humans; Liver Neoplasms; Membrane Glycoproteins; Microscopy, Fluorescence; RNA, Messenger	2015
Rhamnetin induces sensitization of hepatocellular carcinoma cells to a small molecular kinase inhibitor or chemotherapeutic agents. Biochimica et biophysica acta, 2016, Volume: 1860, Issue:7 Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Inhibitory Concentration 50; Liver Neoplasms; Male; Mice, SCID; MicroRNAs; Niacinamide; Paclitaxel; Phenylurea Compounds; Protein Kinase Inhibitors; Quercetin; Receptor, Notch1; Signal Transduction; Sorafenib; Transfection; Xenograft Model Antitumor Assays	2016
High-throughput screening for Survivin and Borealin interaction inhibitors in hepatocellular carcinoma. Biochemical and biophysical research communications, 2017, 03-11, Volume: 484, Issue:3 Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Etoposide; High-Throughput Screening Assays; Humans; Inhibitor of Apoptosis Proteins; Protein Interaction Mapping; Survivin	2017
Association analysis between the Cdc6 G1321A polymorphism and the risk for non-Hodgkin lymphoma and hepatocellular carcinoma. Mutation research, 2009, Mar-09, Volume: 662, Issue:1-2 Topics: Adult; Aged; Apoptosis; Carcinoma, Hepatocellular; Case-Control Studies; Cell Cycle Proteins; Etoposide; Female; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Humans; Liver Neoplasms; Lymphoma, Non-Hodgkin; Male; Middle Aged; Nuclear Proteins; Nucleic Acid Conformation; Polymorphism, Single Nucleotide; RNA, Messenger	2009
The tumor suppressor gene hypermethylated in cancer 1 is transcriptionally regulated by E2F1. Molecular cancer research : MCR, 2009, Volume: 7, Issue:6 Topics: Base Sequence; Binding Sites; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; DNA Methylation; E2F1 Transcription Factor; Etoposide; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Kruppel-Like Transcription Factors; Liver Neoplasms; Lung Neoplasms; Molecular Sequence Data; Promoter Regions, Genetic; RNA, Messenger; Sequence Alignment; Transcription, Genetic; Up-Regulation	2009
Tunicamycin induces resistance to camptothecin and etoposide in human hepatocellular carcinoma cells: role of cell-cycle arrest and GRP78. Naunyn-Schmiedeberg's archives of pharmacology, 2009, Volume: 380, Issue:5 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Drug Resistance, Neoplasm; Endoplasmic Reticulum Chaperone BiP; Etoposide; G1 Phase; Heat-Shock Proteins; Humans; Liver Neoplasms; Tunicamycin	2009
Association of p53 with Bid induces cell death in response to etoposide treatment in hepatocellular carcinoma. Current cancer drug targets, 2009, Volume: 9, Issue:7 Topics: Antineoplastic Agents, Phytogenic; BH3 Interacting Domain Death Agonist Protein; Carcinoma, Hepatocellular; Cell Death; Cell Line; Cell Line, Tumor; Cell Nucleus; Cell Survival; DNA Damage; Etoposide; Humans; Liver Neoplasms; Mitochondria; Protein Binding; Protein Transport; RNA, Small Interfering; Tumor Suppressor Protein p53	2009
Potentiation of etoposide-induced apoptosis in HeLa cells by co-treatment with KG-135, a quality-controlled standardized ginsenoside formulation. Cancer letters, 2010, Aug-01, Volume: 294, Issue:1 Topics: Androstadienes; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Synergism; Etoposide; Female; Ginsenosides; HeLa Cells; Humans; Korea; Liver Neoplasms; Medicine, East Asian Traditional; Membrane Potentials; Mitochondria; Mycotoxins; Phosphoserine; Stomach Neoplasms; Wortmannin	2010
Autophagy inhibition enhances etoposide-induced cell death in human hepatoma G2 cells. International journal of molecular medicine, 2011, Volume: 27, Issue:4 Topics: Adenine; AMP-Activated Protein Kinases; Antineoplastic Agents; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Carcinoma, Hepatocellular; DNA Damage; Etoposide; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Membrane Proteins; RNA, Small Interfering; Signal Transduction; Tumor Suppressor Protein p53	2011
Acetylcholinesterase, a key prognostic predictor for hepatocellular carcinoma, suppresses cell growth and induces chemosensitization. Hepatology (Baltimore, Md.), 2011, Volume: 53, Issue:2 Topics: Acetylcholinesterase; Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Doxorubicin; Etoposide; Female; Humans; Liver Neoplasms; Male; Mice; Middle Aged; Mitogen-Activated Protein Kinase Kinases; Phosphatidylinositol 3-Kinases; Prognosis; Proto-Oncogene Proteins c-akt; Recombinant Proteins; Signal Transduction; Survival Rate; Transplantation, Heterologous	2011
Quinacrine sensitizes hepatocellular carcinoma cells to TRAIL and chemotherapeutic agents. Cancer biology & therapy, 2011, Aug-01, Volume: 12, Issue:3 Topics: Animals; Antineoplastic Agents; Benzenesulfonates; Camptothecin; Carcinoma, Hepatocellular; Cell Death; Cell Nucleus; Cytoplasm; Deoxycytidine; Doxorubicin; Drug Synergism; Etoposide; Female; Fluorouracil; Gemcitabine; Genes, p53; Humans; Irinotecan; Liver Neoplasms; Mice; Microtubule-Associated Proteins; Myeloid Cell Leukemia Sequence 1 Protein; Niacinamide; Phenylurea Compounds; Proto-Oncogene Proteins c-bcl-2; Pyridines; Quinacrine; Receptors, TNF-Related Apoptosis-Inducing Ligand; RNA, Small Interfering; Sorafenib; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2011
Verticillin A overcomes apoptosis resistance in human colon carcinoma through DNA methylation-dependent upregulation of BNIP3. Cancer research, 2011, Nov-01, Volume: 71, Issue:21 Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cisplatin; Colonic Neoplasms; DNA Methylation; Drug Resistance, Neoplasm; Etoposide; Fas Ligand Protein; Female; Gene Expression Regulation, Neoplastic; Humans; Indoles; Liver Neoplasms; Membrane Proteins; Mice; Mice, Nude; Neoplasm Proteins; Promoter Regions, Genetic; Proto-Oncogene Proteins; Recombinant Proteins; RNA Interference; RNA, Small Interfering; TNF-Related Apoptosis-Inducing Ligand; Up-Regulation; Xenograft Model Antitumor Assays	2011
Etoposide induces a mixed type of programmed cell death and overcomes the resistance conferred by Bcl-2 in Hep3B hepatoma cells. International journal of oncology, 2012, Volume: 41, Issue:4 Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Beclin-1; Carcinoma, Hepatocellular; Caspase Inhibitors; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Humans; Liver Neoplasms; Membrane Proteins; Staurosporine	2012
Nrf2-induced antiapoptotic Bcl-xL protein enhances cell survival and drug resistance. Free radical biology & medicine, 2013, Volume: 57 Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidant Response Elements; Antioxidants; Apoptosis; bcl-X Protein; Carcinoma, Hepatocellular; Caspases; Cell Line, Tumor; Cell Survival; Cytoprotection; Drug Resistance, Neoplasm; Etoposide; HEK293 Cells; Hepatoblastoma; Humans; Hydroquinones; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; Liver Neoplasms; Mice; NF-E2-Related Factor 2; Promoter Regions, Genetic; RNA Interference	2013
Efficacy and toxicity of intra-arterial cisplatin and etoposide for advanced hepatocellular carcinoma. Oncology, 2002, Volume: 62, Issue:4 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Etoposide; Female; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Retrospective Studies; Survival Rate	2002
[Regulative function of extracelluar regulated protein kinases and telomerase in apoptosis of hepatocarcinomatous cell SMMC-7721]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2002, Volume: 10, Issue:4 Topics: Apoptosis; Carcinoma, Hepatocellular; Etoposide; Harringtonines; Humans; Liver Neoplasms; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Signal Transduction; Telomerase; Tumor Cells, Cultured; Vincristine	2002
Metallothionein is a potential negative regulator of apoptosis. Toxicological sciences : an official journal of the Society of Toxicology, 2003, Volume: 73, Issue:2 Topics: Apoptosis; Cadmium; Carcinoma, Hepatocellular; Caspase 3; Caspases; Cell Line, Tumor; Cell Survival; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Combinations; Etoposide; Hepatocytes; Humans; Liver Neoplasms; Lung Neoplasms; Metallothionein; Zinc	2003
Autocrine inhibition of chemotherapy response in human liver tumor cells by insulin-like growth factor-II. Cancer letters, 2004, Mar-31, Volume: 206, Issue:1 Topics: Antineoplastic Agents; Apoptosis; Autocrine Communication; Carcinoma, Hepatocellular; Cell Division; Cisplatin; Etoposide; Humans; In Situ Nick-End Labeling; Insulin-Like Growth Factor II; Liver Neoplasms; Tumor Cells, Cultured	2004
Adeno-associated virus mediated endostatin gene therapy in combination with topoisomerase inhibitor effectively controls liver tumor in mouse model. World journal of gastroenterology, 2004, Apr-15, Volume: 10, Issue:8 Topics: Adenoviridae; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Hepatocellular; Cell Line, Tumor; Combined Modality Therapy; Drug Synergism; Endostatins; Endothelium, Vascular; Enzyme Inhibitors; Etoposide; Gene Expression; Genetic Therapy; Humans; Liver Neoplasms; Mice; Sarcoma; Survival Rate; Topoisomerase Inhibitors; Umbilical Veins	2004
In vitro transdifferentiation of hepatoma cells into functional pancreatic cells. Mechanisms of development, 2005, Volume: 122, Issue:6 Topics: Active Transport, Cell Nucleus; Animals; Betacellulin; Carcinoma, Hepatocellular; Cell Culture Techniques; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Etoposide; Gene Expression Regulation; Gene Expression Regulation, Developmental; Glucagon; Glucagon-Like Peptide 1; Hepatocytes; Homeodomain Proteins; Humans; Insulin; Intercellular Signaling Peptides and Proteins; Islets of Langerhans Transplantation; Liver; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Pancreas; Peptide Fragments; Phenotype; Plasmids; Polymerase Chain Reaction; Protein Precursors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Somatostatin; Time Factors; Trans-Activators; Transgenes	2005
GSK-3beta reactivation with LY294002 sensitizes hepatoma cells to chemotherapy-induced apoptosis. International journal of oncology, 2005, Volume: 27, Issue:1 Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Camptothecin; Carcinoma, Hepatocellular; Caspase 3; Caspase 8; Caspases; Cell Line, Tumor; Chromones; Cytochromes c; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Etoposide; fas Receptor; Flow Cytometry; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Morpholines; Mutation; Phosphatidylinositol 3-Kinases; Phosphorylation; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Reverse Transcriptase Polymerase Chain Reaction; Serine; Transfection; Tumor Suppressor Protein p53	2005
Role of interleukin-18 and its receptor in hepatocellular carcinoma associated with hepatitis C virus infection. International journal of cancer, 2006, Feb-01, Volume: 118, Issue:3 Topics: Aged; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-X Protein; Carcinoma, Hepatocellular; Cytokines; Electrophoretic Mobility Shift Assay; Etoposide; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Interleukin-18; Interleukin-18 Receptor alpha Subunit; Liver Neoplasms; Male; Middle Aged; NF-kappa B; Receptors, Interleukin; Receptors, Interleukin-18; Recombinant Proteins; RNA, Messenger; Survival Rate; X-Linked Inhibitor of Apoptosis Protein	2006
Transfection of Smac sensitizes tumor cells to etoposide-induced apoptosis and eradicates established human hepatoma in vivo. Cancer gene therapy, 2006, Volume: 13, Issue:4 Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Bone Neoplasms; Carcinoma, Hepatocellular; Cell Line, Tumor; Combined Modality Therapy; Etoposide; Female; Fluorouracil; Genetic Therapy; Humans; Intracellular Signaling Peptides and Proteins; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondrial Proteins; Osteosarcoma; Proto-Oncogene Proteins c-bcl-2; Transfection; Tumor Suppressor Protein p53	2006
[The hepatic artery injection chemotherapy and prostaglandin E1 administration for hepatocellular carcinoma invading the biliary tract with jaundice]. Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:11 Topics: Aged; Alprostadil; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neoplasms; Carcinoma, Hepatocellular; Cyclophosphamide; Doxorubicin; Etoposide; Fluorouracil; Humans; Injections, Intra-Arterial; Jaundice; Liver Neoplasms; Male	2005
3,3'-diindolylmethane is a novel topoisomerase IIalpha catalytic inhibitor that induces S-phase retardation and mitotic delay in human hepatoma HepG2 cells. Molecular pharmacology, 2006, Volume: 69, Issue:4 Topics: Antigens, Neoplasm; Carcinoma, Hepatocellular; Cell Line, Tumor; Comet Assay; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Neoplasm; Etoposide; Humans; Indoles; Liver Neoplasms; Microscopy, Confocal; Mitosis; S Phase; Topoisomerase II Inhibitors	2006
Hypoxia protects HepG2 cells against etoposide-induced apoptosis via a HIF-1-independent pathway. Experimental cell research, 2006, Sep-10, Volume: 312, Issue:15 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Caspases; Cell Hypoxia; Cobalt; DNA Fragmentation; Etoposide; Fluorescent Antibody Technique; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; RNA, Small Interfering; Signal Transduction; Transcription Factor AP-1; Transfection; Tumor Cells, Cultured	2006
Statins induce mammalian target of rapamycin (mTOR)-mediated inhibition of Akt signaling and sensitize p53-deficient cells to cytostatic drugs. Molecular cancer therapeutics, 2006, Volume: 5, Issue:11 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Atorvastatin; Carcinoma, Hepatocellular; Cell Proliferation; Chromones; Dose-Response Relationship, Drug; Etoposide; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver Neoplasms; Morpholines; Phosphorylation; Pravastatin; Protein Kinases; Proto-Oncogene Proteins c-akt; Pyrroles; Signal Transduction; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53	2006
Evidence of a novel antiapoptotic factor: role of inhibitor of differentiation or DNA binding (Id-1) in anticancer drug-induced apoptosis. Cancer science, 2007, Volume: 98, Issue:3 Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cell Survival; Cisplatin; Down-Regulation; Doxorubicin; Etoposide; Female; HeLa Cells; Humans; Inhibitor of Differentiation Protein 1; Liver Neoplasms; Male; Mechlorethamine; Methotrexate; Mitomycin; Nasopharyngeal Neoplasms; Paclitaxel; Prostatic Neoplasms; Vincristine	2007
Synergic CSE1L/CAS, TNFR-1, and p53 apoptotic pathways in combined interferon-gamma/adriamycin-induced apoptosis of Hep G2 hepatoma cells. Journal of experimental & clinical cancer research : CR, 2007, Volume: 26, Issue:1 Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Cellular Apoptosis Susceptibility Protein; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Etoposide; Humans; Interferon Regulatory Factor-1; Interferon-gamma; Liver Neoplasms; Receptors, Tumor Necrosis Factor, Type I; Signal Transduction; Transfection; Tumor Suppressor Protein p53	2007
Bcl-2 gene silencing in pediatric epithelial liver tumors. The Journal of surgical research, 2008, Volume: 144, Issue:1 Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Child; Cisplatin; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Epithelium; Etoposide; Gene Silencing; Genetic Therapy; Humans; Liver Neoplasms; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; Transfection	2008
Seleno-podophyllotoxin derivatives induce hepatoma SMMC-7721 cell apoptosis through Bax pathway. Cell biology international, 2008, Volume: 32, Issue:2 Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Shape; Cytochromes c; Etoposide; Humans; Liver Neoplasms; Membrane Potentials; Mitochondria; Molecular Structure; Podophyllotoxin	2008
Efficacy and safety of epirubicin and etoposide combination chemotherapy in advanced hepatocellular carcinoma: a retrospective analysis. Journal of gastroenterology and hepatology, 2008, Volume: 23, Issue:5 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Epirubicin; Etoposide; Female; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Retrospective Studies	2008
Cytotoxic effects and in vitro reversal of multidrug resistance by therapeutic ultrasound in human hepatocarcinoma cell line (HepG2). Ultrasonics, 2008, Volume: 48, Issue:4 Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cisplatin; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Flow Cytometry; Fluorouracil; Humans; In Vitro Techniques; Liver Neoplasms; Rhodamines; Ultrasonic Therapy; Vincristine	2008
Bid exhibits S phase checkpoint activation and plays a pro-apoptotic role in response to etoposide-induced DNA damage in hepatocellular carcinoma cells. Apoptosis : an international journal on programmed cell death, 2008, Volume: 13, Issue:5 Topics: Apoptosis; BH3 Interacting Domain Death Agonist Protein; Carcinoma, Hepatocellular; Cell Line, Tumor; DNA Damage; Down-Regulation; Etoposide; Humans; Liver Neoplasms; S Phase; Tumor Suppressor Protein p53	2008
Diamminodichloride platinum (cis-platinum) in the treatment of hepatocellular carcinoma. Clinical oncology, 1981, Volume: 7, Issue:4 Topics: Adolescent; Adult; Aged; alpha-Fetoproteins; Carcinoma, Hepatocellular; Cisplatin; Doxorubicin; Etoposide; Female; Humans; Kidney Function Tests; Liver Neoplasms; Male; Middle Aged; Nausea; Time Factors; Vomiting	1981
Phase II study of oral VP-16-213 in hepatocellular carcinoma. European journal of cancer & clinical oncology, 1981, Volume: 17, Issue:10 Topics: Adult; Aged; Carcinoma, Hepatocellular; Drug Evaluation; Etoposide; Humans; Liver Neoplasms; Middle Aged; Podophyllotoxin	1981
Etoposide single-agent chemotherapy for solid tumors. Cancer treatment reviews, 1982, Volume: 9 Suppl Topics: Carcinoma, Hepatocellular; Etoposide; Female; Head and Neck Neoplasms; Humans; Liver Neoplasms; Neoplasms; Ovarian Neoplasms; Podophyllotoxin; Sarcoma; Soft Tissue Neoplasms	1982
Apoptosis and nuclear levels of p53 protein and proliferating cell nuclear antigen in human hepatoma cells cultured with tumor promoters. Cancer letters, 1995, May-04, Volume: 91, Issue:1 Topics: Apoptosis; Carcinogens; Carcinoma, Hepatocellular; DNA Damage; Etoposide; Flow Cytometry; Humans; Lyngbya Toxins; Mitomycin; Proliferating Cell Nuclear Antigen; Terpenes; Thapsigargin; Tumor Cells, Cultured; Tumor Suppressor Protein p53	1995
Combination therapy consisting of arterial infusion chemotherapy (EPF, EAP) and transcatheter arterial embolization (TAE). Cancer chemotherapy and pharmacology, 1994, Volume: 33 Suppl Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Cisplatin; Combined Modality Therapy; Doxorubicin; Etoposide; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Iodized Oil; Liver Neoplasms; Male; Middle Aged; Survival Rate; Tomography, X-Ray Computed	1994
[Effects of cisplatin, carboplatin, etoposide and human hepatocyte growth factor on the colony formation of four human liver cancer cell lines]. Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:13 Topics: Carboplatin; Carcinoma, Hepatocellular; Cisplatin; Drug Synergism; Etoposide; Hepatoblastoma; Hepatocyte Growth Factor; Humans; Liver Neoplasms; Neoplastic Stem Cells; Recombinant Proteins; Tumor Cells, Cultured	1993
[The effect and pharmacokinetics of etoposide in patients with primary hepatocellular carcinoma]. Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:1 Topics: Administration, Oral; Carcinoma, Hepatocellular; Drug Administration Schedule; Etoposide; Female; Humans; Liver Neoplasms; Male; Middle Aged	1993
Cisplatin-resistant metastatic hepatoblastoma: complete response to carboplatin, etoposide, and liver transplantation. Medical and pediatric oncology, 1993, Volume: 21, Issue:7 Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Hepatocellular; Cisplatin; Combined Modality Therapy; Drug Resistance; Etoposide; Female; Humans; Infant; Liver Neoplasms; Liver Transplantation; Lung Neoplasms; Remission Induction	1993
[Therapy-related AML(M2) with t(8;21) that developed three years after chemotherapy for hepatocellular carcinoma]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 1996, Volume: 37, Issue:5 Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Hepatocellular; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Doxorubicin; Epirubicin; Etoposide; Humans; Leukemia, Myeloid, Acute; Liver Neoplasms; Male; Middle Aged; Neoplasms, Second Primary; Translocation, Genetic	1996
[A patient with HCC successfully treated by ethanol injection therapy with etoposide]. Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:11 Topics: Aged; Carcinoma, Hepatocellular; Embolization, Therapeutic; Ethanol; Etoposide; Humans; Injections, Intralesional; Liver Neoplasms; Male	1996
Determination of unbound etoposide concentration in ultrafiltered plasma by high-performance liquid chromatography with fluorimetric detection. Journal of chromatography. B, Biomedical applications, 1996, Nov-08, Volume: 686, Issue:1 Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Calibration; Carcinoma, Hepatocellular; Chromatography, High Pressure Liquid; Etoposide; Fluorometry; Hemofiltration; Humans; Linear Models; Liver Neoplasms; Middle Aged; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet	1996
Selective induction of apoptosis in Hep 3B cells by topoisomerase I inhibitors: evidence for a protease-dependent pathway that does not activate cysteine protease P32. The Journal of clinical investigation, 1996, Dec-01, Volume: 98, Issue:11 Topics: Apoptosis; Camptothecin; Carcinoma, Hepatocellular; Caspase 1; Caspase 3; Caspases; Cell Line; Cysteine Endopeptidases; Endopeptidases; Enzyme Inhibitors; Etoposide; Humans; Kinetics; Liver Neoplasms; Protease Inhibitors; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured	1996
[Chemosensitivity test on hepatocellular carcinoma (HCC) and drug resistance]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1996, Volume: 71, Issue:6 Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Cisplatin; Cytochrome P-450 Enzyme System; Doxorubicin; Drug Screening Assays, Antitumor; Etoposide; Fluorouracil; Glutathione Transferase; Humans; Liver Neoplasms; Metallothionein; Mitomycins; Tumor Cells, Cultured	1996
Expression of P-glycoprotein and p53 in advanced hepatocellular carcinoma treated by single agent chemotherapy: clinical correlation. Journal of gastroenterology and hepatology, 1997, Volume: 12, Issue:8 Topics: Adult; Aged; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Doxorubicin; Etoposide; Female; Humans; Immunohistochemistry; Liver Neoplasms; Male; Middle Aged; Tumor Suppressor Protein p53	1997
Pharmacokinetics of oral etoposide in patients with hepatocellular carcinoma. Cancer chemotherapy and pharmacology, 1999, Volume: 43, Issue:4 Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Aspartate Aminotransferases; Bilirubin; Biological Availability; Blood Proteins; Carcinoma, Hepatocellular; Chromatography, High Pressure Liquid; Etoposide; Humans; Lidocaine; Liver Cirrhosis; Liver Function Tests; Liver Neoplasms; Metabolic Clearance Rate; Middle Aged; Protein Binding; Serum Albumin; Ultrafiltration	1999
Depletion of cellular glutathione by conditions used for the passaging of adherent cultured cells. Toxicology letters, 2000, May-19, Volume: 115, Issue:2 Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Communication; Cell Culture Techniques; Cell Death; Etoposide; Female; Glutathione; Humans; Hydrogen Peroxide; Liver Neoplasms; Oxidants; Rats; Toxicity Tests; Tumor Cells, Cultured	2000
Transduction of hepatocellular carcinoma (HCC) using recombinant adeno-associated virus (rAAV): in vitro and in vivo effects of genotoxic agents. Journal of hepatology, 2000, Volume: 32, Issue:6 Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Cell Line; Dependovirus; Etoposide; Gamma Rays; Gene Transfer Techniques; Genetic Vectors; Humans; Liver; Liver Neoplasms; Mice; Mice, Nude; Mutagens; Neoplasm Transplantation; Rats; Rats, Inbred BUF; Recombination, Genetic; Transduction, Genetic; Tumor Cells, Cultured	2000
[Hepatic arterial infusion chemotherapy using totally implantable port system]. Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:10 Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Doxorubicin; Drug Administration Schedule; Epirubicin; Etoposide; Fluorouracil; Hepatic Artery; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Liver Neoplasms; Mitomycin	2000
Epipodophyllin derivative (VP 16-213) in treatment of solid tumours. Lancet (London, England), 1977, Aug-13, Volume: 2, Issue:8033 Topics: Carcinoma, Hepatocellular; Etoposide; Humans; Liver Neoplasms; Podophyllotoxin; Teratoma	1977
[Therapeutic results using VP 16-213 alone or in combination with 5-fluorouracil in liver cancer (hepatoma)]. Schweizerische medizinische Wochenschrift, 1977, Dec-31, Volume: 107, Issue:52 Topics: Adult; Aged; Carcinoma, Hepatocellular; Drug Therapy, Combination; Etoposide; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Middle Aged; Podophyllotoxin	1977
[A case with hepatocellular carcinoma effectively treated by continuous hepatic arterial infusion of etoposide, epirubicin and CDDP]. Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Epirubicin; Etoposide; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged	1992
Cisplatin therapy in infants: short and long-term morbidity. The British journal of cancer. Supplement, 1992, Volume: 18 Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Chlorambucil; Cisplatin; Electrolytes; Etoposide; Female; Glomerular Filtration Rate; Humans; Infant; Infant, Newborn; Liver Neoplasms; Male; Morbidity; Neuroblastoma; Prednisolone; Seizures; Teratoma; Time Factors; Vincristine	1992
Arterial infusion chemotherapy for advanced hepatocellular carcinoma using EPF and EAP therapies. Cancer chemotherapy and pharmacology, 1992, Volume: 31 Suppl Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Doxorubicin; Etoposide; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged	1992
Prognostic factors in patients with hepatocellular carcinoma receiving systemic chemotherapy. Hepatology (Baltimore, Md.), 1992, Volume: 16, Issue:1 Topics: alpha-Fetoproteins; Analysis of Variance; Antineoplastic Agents; Ascites; Bilirubin; Carcinoma, Hepatocellular; Cisplatin; Doxorubicin; Etoposide; Female; Fluorouracil; Follow-Up Studies; Humans; Interferon-gamma; Liver Neoplasms; Male; Middle Aged; Mitoxantrone; Multivariate Analysis; Prognosis; Regression Analysis; Risk Factors; Serum Albumin; Tegafur; Time Factors	1992
[Intra-arterial infusion chemotherapy for unresectable hepatocellular carcinoma using an implantable reservoir]. Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:11 Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Hepatocellular; Cisplatin; Doxorubicin; Etoposide; Fluorouracil; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Liver Neoplasms; Middle Aged; Mitomycin; Mitomycins	1991
An application of recombinant human granulocyte colony-stimulating factor (rhG-CSF) in a case of hepatocellular carcinoma combined with liver cirrhosis in which leukopenia developed after chemoembolization. Gastroenterologia Japonica, 1991, Volume: 26, Issue:6 Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Doxorubicin; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Liver Cirrhosis; Liver Neoplasms; Middle Aged; Neutropenia; Recombinant Proteins	1991
[Chemoembolization therapy with lipiodol, cisplatin and etoposide for hepatocellular carcinoma]. Nihon Gan Chiryo Gakkai shi, 1990, Dec-20, Volume: 25, Issue:12 Topics: Aged; Carcinoma, Hepatocellular; Catheterization; Cisplatin; Embolization, Therapeutic; Etoposide; Female; Gelatin Sponge, Absorbable; Hepatic Artery; Humans; Iodized Oil; Liver Neoplasms; Male; Middle Aged	1990
[Treatment of liver metastatic ovarian cancer with sequential administration of OK-432 and etoposide]. Nihon Gan Chiryo Gakkai shi, 1990, Dec-20, Volume: 25, Issue:12 Topics: Adult; Carcinoma, Hepatocellular; Etoposide; Female; Humans; Injections, Intravenous; Liver Neoplasms; Ovarian Neoplasms; Picibanil	1990
[Hepatocellular carcinoma treated by continuous hepatic arterial infusion of etoposide, CDDP and 5-FU]. Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:1 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Drug Administration Schedule; Etoposide; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged	1990
[Hepatic arterial infusion of etoposide in the treatment of primary liver neoplasms]. Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:3 Pt 1 Topics: Adenoma, Bile Duct; Bile Duct Neoplasms; Carcinoma, Hepatocellular; Etoposide; Female; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged	1990
[Intra-hepato-arterial infusion chemotherapy using catheter inserted and placed in hepatic artery via the left radial artery on liver malignancy]. Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:3 Pt 1 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Catheterization; Cisplatin; Colonic Neoplasms; Embolization, Therapeutic; Etoposide; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Mitomycin; Mitomycins; Stomach Neoplasms	1990
A phase II study of etoposide in patients with hepatocellular carcinoma by the Tokyo Liver Cancer Chemotherapy Study Group. Japanese journal of clinical oncology, 1989, Volume: 19, Issue:2 Topics: Aged; alpha-Fetoproteins; Carcinoma, Hepatocellular; Drug Evaluation; Etoposide; Female; Humans; Leukocyte Count; Liver Neoplasms; Male; Middle Aged; Platelet Count; Remission Induction	1989
[A case of hepatocellular carcinoma effectively treated by intraarterial infusion of CDDP and other agents]. Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:9 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Embolization, Therapeutic; Etoposide; Fluorouracil; Humans; Iodized Oil; Liver Neoplasms; Male	1989
A pleomorphic hepatocellular carcinoma with biochemical features of fibrolamellar hepatocellular carcinoma. Journal of surgical oncology, 1986, Volume: 32, Issue:2 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Combined Modality Therapy; Doxorubicin; Etoposide; Female; Folic Acid; Humans; Liver Neoplasms; Neurotensin; Quinazolines; Vitamin B 12	1986
Long-term survival and complete response to adriamycin and etoposide in a case of hepatocellular carcinoma. Tumori, 1986, Aug-31, Volume: 72, Issue:4 Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Doxorubicin; Etoposide; Female; Humans; Liver Neoplasms; Middle Aged	1986
Phase 2 study of high dose etoposide (VP16-213) in hepatocellular carcinoma. Japanese journal of clinical oncology, 1987, Volume: 17, Issue:2 Topics: Blood; Carcinoma, Hepatocellular; Drug Evaluation; Etoposide; Humans; Liver Neoplasms	1987
[The effect of etoposide (Et) on primary hepatocellular carcinoma]. Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:8 Topics: Aged; Carcinoma, Hepatocellular; Etoposide; Female; Humans; Liver Neoplasms; Male; Middle Aged	1987