Compounds > etoposide
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etoposide and Ataxia Telangiectasia

etoposide has been researched along with Ataxia Telangiectasia in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19903 (14.29)18.7374
1990's10 (47.62)18.2507
2000's5 (23.81)29.6817
2010's2 (9.52)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Dou, X; Huang, H; Jiang, L; Jiao, N; Jin, H; Jin, Z; Li, Z; Liu, Y; Liu, Z; Sun, X; Zhang, L; Zhu, G; Zou, Y1
Hudson, MM; Kastan, MB; Kennedy, W; Onciu, M; Sandlund, JT1
Li, Y; Xiong, H; Yang, DQ1
Ball, KL; Dornan, D; Kelleher, M; Pamment, J; Ramsay, E1
Antonelli, A; Biroccio, A; Elli, R; Gabellini, C; Marcucci, L; Nigro, G; Petrinelli, P; Russo, G; Zupi, G1
Artac, H; Caliskan, U; Ilerisoy-Yakut, Z; Koksal, Y; Reisli, I; Ucar, C; Yurtcu, M1
Jongmans, W; Lohman, PH; Sankaranarayanan, K; Verhaegh, GW; Zdzienicka, MZ1
Caporossi, D; De Salvia, R; Degrassi, F; Nicoletti, B; Palitti, F; Porfirio, B; Tanzarella, C1
Ambra, R; Antonelli, A; Chessa, L; Elli, R; Marcucci, L; Petrinelli, P1
Ambra, R; Antonelli, A; Barbieri, C; Elli, R; Marcucci, L; Petrinelli, P1
Maser, RS; Monsen, KJ; Nelms, BE; Petrini, JH1
Caporossi, D; Fantini, C; Tedeschi, B; Vernole, P1
Cao, CX; Kohn, KW; Pommier, Y; Shao, RG; Wold, MS; Zhang, H1
d'Adda di Fagagna, F; Jackson, SP; Lakin, ND; Smith, GC1
Bay, JO; Bignon, YJ; Pernin, D; Uhrhammer, N1
Bryant, PE; Johnson, MA; Jones, NJ1
Coisy, M; Concannon, P; Darbon, JM; Ducommun, B; Théard, D1
Antonelli, A; Bosi, R; Elli, R; Kobal, D; Marcucci, L; Petrinelli, P1
Blazka, ME; Henner, WD1
Downes, CS; Johnson, RT; Mullinger, AM1
Anderson, CO; Smith, PJ; Watson, JV1

Reviews

1 review(s) available for etoposide and Ataxia Telangiectasia

ArticleYear
Dysgerminoma in a child with ataxia-telangiectasia.
    Pediatric hematology and oncology, 2007, Volume: 24, Issue:6

    Topics: alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Ataxia Telangiectasia; Biomarkers, Tumor; Bleomycin; CA-125 Antigen; Carboplatin; Child; Chorionic Gonadotropin, beta Subunit, Human; Dysgerminoma; Etoposide; Female; Follow-Up Studies; Genetic Predisposition to Disease; Humans; Immunoglobulins, Intravenous; Neoplasm Proteins; Ovarian Neoplasms; Ovariectomy; Respiration Disorders

2007

Other Studies

20 other study(ies) available for etoposide and Ataxia Telangiectasia

ArticleYear
Discovery of novel ataxia telangiectasia mutated (ATM) kinase modulators: Computational simulation, biological evaluation and cancer combinational chemotherapy study.
    European journal of medicinal chemistry, 2022, Apr-05, Volume: 233

    Topics: Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line, Tumor; DNA-Binding Proteins; Humans; Neoplasms; Phosphorylation; Protein Serine-Threonine Kinases

2022
Pilot study of modified LMB-based therapy for children with ataxia-telangiectasia and advanced stage high grade mature B-cell malignancies.
    Pediatric blood & cancer, 2014, Volume: 61, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Ataxia Telangiectasia; Child; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Hydrocortisone; Leucovorin; Lymphoma, B-Cell; Male; Methotrexate; Neoplasm Staging; Pilot Projects; Prednisone; Prognosis; Prospective Studies; Vincristine; Young Adult

2014
Functional switching of ATM: sensor of DNA damage in proliferating cells and mediator of Akt survival signal in post-mitotic human neuron-like cells.
    Chinese journal of cancer, 2012, Volume: 31, Issue:8

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Camptothecin; Cell Cycle Proteins; Cell Differentiation; Cell Line, Tumor; DNA Damage; DNA-Binding Proteins; Etoposide; Histones; Humans; Morpholines; Neuroblastoma; Neurons; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Pyrones; Signal Transduction; Topoisomerase Inhibitors; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

2012
Regulation of the IRF-1 tumour modifier during the response to genotoxic stress involves an ATM-dependent signalling pathway.
    Oncogene, 2002, Nov-07, Volume: 21, Issue:51

    Topics: Androstadienes; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cycloheximide; DNA; DNA Damage; DNA-Binding Proteins; Enzyme Inhibitors; Etoposide; Fibroblasts; Gamma Rays; Genes, p53; Genes, Reporter; Humans; Interferon Regulatory Factor-1; Melanoma; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Poly I-C; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Recombinant Fusion Proteins; RNA, Messenger; Signal Transduction; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Wortmannin

2002
Telomerase activity, apoptosis and cell cycle progression in ataxia telangiectasia lymphocytes expressing TCL1.
    British journal of cancer, 2003, Sep-15, Volume: 89, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Ataxia Telangiectasia; Cell Cycle; Cell Transformation, Neoplastic; Chromosomes, Human, Pair 14; Clone Cells; DNA-Binding Proteins; Etoposide; Gene Expression Regulation; Humans; Preleukemia; Proto-Oncogene Proteins; T-Lymphocytes; Telomerase; Telomere; Transcription Factors; Translocation, Genetic

2003
Cellular characteristics of Chinese hamster cell mutants resembling ataxia telangiectasia cells.
    Mutation research, 1993, Volume: 294, Issue:3

    Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Ataxia Telangiectasia; Cell Line; Cell Survival; Cricetinae; Doxorubicin; Enediynes; Etoposide; Humans; Hypoxanthine Phosphoribosyltransferase; Mutagens; Mutation; Streptonigrin

1993
Hypersensitivity of lymphoblastoid lines derived from ataxia telangiectasia patients to the induction of chromosomal aberrations by etoposide (VP-16).
    Mutation research, 1993, Volume: 290, Issue:2

    Topics: Ataxia Telangiectasia; Cell Cycle; Cell Line; Chromosome Aberrations; DNA Damage; DNA Replication; Dose-Response Relationship, Drug; Etoposide; Female; G2 Phase; Humans; Lymphocytes; Male; Mitotic Index; Mutagens; S Phase

1993
Effects of topoisomerase II inhibition in lymphoblasts from patients with progeroid and "chromosome instability" syndromes.
    Cancer genetics and cytogenetics, 1996, Volume: 87, Issue:2

    Topics: Ataxia Telangiectasia; Bleomycin; Bloom Syndrome; Cell Line; Cockayne Syndrome; DNA Damage; Etoposide; Genetic Diseases, Inborn; Humans; Lymphocytes; Topoisomerase II Inhibitors; Werner Syndrome; Xeroderma Pigmentosum

1996
VP16 hypersensitivity and increased faulty recombination in ataxia telangiectasia lymphocytes characterized by the tandem translocation t(14;14)(q11;q32).
    Carcinogenesis, 1996, Volume: 17, Issue:2

    Topics: Adolescent; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Ataxia Telangiectasia; Bleomycin; Chromosomes, Human, Pair 14; Etoposide; Female; Humans; Sister Chromatid Exchange; T-Lymphocytes; Translocation, Genetic

1996
hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks.
    Molecular and cellular biology, 1997, Volume: 17, Issue:10

    Topics: Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Nucleus; Cells, Cultured; DNA Damage; DNA Repair; DNA-Binding Proteins; Endodeoxyribonucleases; Enzyme Inhibitors; Etoposide; Exodeoxyribonucleases; Fibroblasts; Fungal Proteins; G2 Phase; Gamma Rays; Humans; Mutation; Protein Serine-Threonine Kinases; Proteins; Rad51 Recombinase; Saccharomyces cerevisiae Proteins; Signal Transduction; Topoisomerase II Inhibitors; Tumor Suppressor Proteins

1997
Sister chromatid exchanges and DNA topoisomerase II inhibitors: effect of low concentrations of etoposide (VP-16) in ataxia telangiectasia lymphoblastoid cell lines.
    Mutation research, 1998, Jan-13, Volume: 412, Issue:1

    Topics: Ataxia Telangiectasia; Cell Division; Cell Line; Cell Line, Transformed; Enzyme Inhibitors; Etoposide; Female; Herpesvirus 4, Human; Heterozygote; Homozygote; Humans; Lymphocytes; Male; Mitotic Index; Mutagens; Recombination, Genetic; Reference Values; Sister Chromatid Exchange; Topoisomerase II Inhibitors

1998
Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA:DNA-PK complexes.
    The EMBO journal, 1999, Mar-01, Volume: 18, Issue:5

    Topics: Alkaloids; Androstadienes; Antigens, Nuclear; Ataxia Telangiectasia; Camptothecin; Cell Cycle; DNA Damage; DNA Helicases; DNA Repair; DNA Replication; DNA Topoisomerases, Type I; DNA-Activated Protein Kinase; DNA-Binding Proteins; Etoposide; Humans; Ku Autoantigen; Nuclear Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Replication Protein A; Staurosporine; Tumor Cells, Cultured; Wortmannin

1999
Cleavage and inactivation of ATM during apoptosis.
    Molecular and cellular biology, 1999, Volume: 19, Issue:9

    Topics: Amino Acid Sequence; Apoptosis; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Base Sequence; Binding Sites; Caspase 3; Caspase 6; Caspases; Cell Cycle Proteins; DNA; DNA Damage; DNA Primers; DNA Repair; DNA-Binding Proteins; Enzyme Inhibitors; Epitope Mapping; Etoposide; HeLa Cells; HL-60 Cells; Humans; Protein Binding; Protein Serine-Threonine Kinases; Proteins; Recombinant Fusion Proteins; Signal Transduction; Topoisomerase II Inhibitors; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

1999
ATM heterozygote cells exhibit intermediate levels of apoptosis in response to streptonigrin and etoposide.
    European journal of cancer (Oxford, England : 1990), 1999, Volume: 35, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Ataxia Telangiectasia; Cell Line; Etoposide; Genetic Carrier Screening; Heterozygote; Humans; Streptonigrin

1999
Isolation of camptothecin-sensitive chinese hamster cell mutants: phenotypic heterogeneity within the ataxia telangiectasia-like XRCC8 (irs2) complementation group.
    Mutagenesis, 2000, Volume: 15, Issue:4

    Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Bleomycin; Camptothecin; Cell Cycle; Cell Cycle Proteins; Cell Line; Cricetinae; DNA Repair; DNA-Binding Proteins; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Doxorubicin; Enzyme Inhibitors; Etoposide; Gamma Rays; Genes, Dominant; Genetic Complementation Test; Mitomycin; Mutation; Nucleic Acid Synthesis Inhibitors; Phenotype; Protein Serine-Threonine Kinases; Streptonigrin; Tumor Suppressor Proteins

2000
Etoposide and adriamycin but not genistein can activate the checkpoint kinase Chk2 independently of ATM/ATR.
    Biochemical and biophysical research communications, 2001, Dec-21, Volume: 289, Issue:5

    Topics: Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line; Checkpoint Kinase 2; DNA Damage; DNA-Binding Proteins; Doxorubicin; Enzyme Activation; Enzyme Inhibitors; Etoposide; G2 Phase; Genistein; Humans; Mutagens; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Topoisomerase II Inhibitors; Tumor Suppressor Proteins

2001
Human cells (normal and ataxia telangiectasia) transfected with pR plasmid are hypersensitive to DNA strand-breaking agents.
    Mutation research, 1991, Volume: 255, Issue:1

    Topics: Ataxia Telangiectasia; Bleomycin; Cell Line, Transformed; Cell Survival; Chromosome Aberrations; DNA Damage; DNA Repair; Etoposide; Fibroblasts; Herpesvirus 4, Human; Humans; Lymphocytes; Plasmids; SOS Response, Genetics; Transfection

1991
Hypersensitivity of cultured ataxia-telangiectasia cells to etoposide.
    Journal of the National Cancer Institute, 1986, Volume: 76, Issue:6

    Topics: Aminoacridines; Amsacrine; Ataxia Telangiectasia; Bleomycin; Cell Survival; Cells, Cultured; DNA; Etoposide; Fibroblasts; Humans; Podophyllotoxin

1986
Action of etoposide (VP-16-123) on human cells: no evidence for topoisomerase II involvement in excision repair of u.v.-induced DNA damage, nor for mitochondrial hypersensitivity in ataxia telangiectasia.
    Carcinogenesis, 1987, Volume: 8, Issue:11

    Topics: Ataxia Telangiectasia; Cell Survival; Cells, Cultured; Chromosomes; DNA; DNA Damage; DNA Repair; DNA Topoisomerases, Type II; Etoposide; Humans; Mitochondria; Novobiocin; Ultraviolet Rays

1987
Predominant role for DNA damage in etoposide-induced cytotoxicity and cell cycle perturbation in human SV40-transformed fibroblasts.
    Cancer research, 1986, Volume: 46, Issue:11

    Topics: Ataxia Telangiectasia; Cell Cycle; Cell Survival; Cell Transformation, Viral; Cells, Cultured; DNA; DNA Damage; DNA Repair; Etoposide; Humans; Simian virus 40

1986