etoposide has been researched along with Astrocytoma, Grade IV in 122 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.82) | 18.7374 |
| 1990's | 25 (20.49) | 18.2507 |
| 2000's | 42 (34.43) | 29.6817 |
| 2010's | 44 (36.07) | 24.3611 |
| 2020's | 10 (8.20) | 2.80 |
| Authors | Studies |
|---|---|
| Cai, W; Hao, Y; Hu, P; Ma, D; Pan, H; Xie, X; Yu, AD; Yu, J; Yuan, J; Zhang, L; Zhu, H | 1 |
| Andricopulo, AD; Beraldo, H; Da Silva, JG; Daghestani, H; Day, BW; Dos Santos, RG; Lessa, JA; Mendes, IC; Pesquero, JL; Rocha, WR; Salum, LB; Soares, MA; Vogt, A | 1 |
| Cho, H; Elkamhawy, A; Heo, JC; Kim, HY; Kim, KH; Lee, CO; Nam, DH; Pae, AN; Park, WK; Roh, EJ; Seol, HJ; Viswanath, AN; Yang, H | 1 |
| Banach, K; Beberok, A; Karkoszka, M; Maszczyk, M; Rok, J; Rzepka, Z; Wrześniok, D | 1 |
| Abu-Gharbieh, E; Abuhelwa, AY; Ahmed, M; Alqudah, MAY; Alsoud, LO; Alzoubi, KH; Bustanji, Y; El-Awady, R; El-Huneidi, W; Ramadan, WS; Semreen, AM; Semreen, MH; Shara, M; Soares, NC | 1 |
| Gulbas, I; Kopa, P; Macieja, A; Pastwa, E; Poplawski, T | 1 |
| Contreras-Ochoa, CO; Díaz-Chávez, J; Lagunas-Martínez, A; López-Arellano, ME; Madrid-Marina, V; Moreno-Banda, GL; Munguía-Moreno, JA; Reyna-Figueroa, J; Roblero-Bartolon, G | 1 |
| Ahmed, A; Awah, CU; Balyasnikova, IV; Bansal, M; Burdett, KB; Chen, L; Feldstein, E; Gonzalez-Buendia, E; Győrffy, B; Hsu, P; Konerman, S; Lad, M; Mahajan, A; Martuscello, R; Park, C; Scholtens, DM; Sonabend, AM; Stupp, R; Warnke, L; Winter, J; Yu, D; Zannikou, M; Zhang, D | 1 |
| Clarke, PA; Fay, M; Lovato, T; Marlow, M; McCrorie, P; Mistry, J; Rahman, R; Ritchie, AA; Smith, SJ; Taresco, V; Ward, I | 1 |
| Bruce, JN; Canoll, PD; Englander, ZK; Feldstein, NA; Guo, J; Jan, CI; Konofagou, EE; Mela, A; Pouliopoulos, AN; Upadhyayula, PS; Wang, TJC; Wei, HJ; Wu, CC; Zacharoulis, S; Zhang, X; Zhang, Z | 1 |
| Mathen, P; Smart, DK | 1 |
| Adabi, M; Ghanbari, H; Hadjighassem, MR; Hosseini Najafabadi, MR; Khosravani, M; Maleki, H; Sadroddiny, E; Webster, TJ | 1 |
| Beberok, A; Maszczyk, M; Rok, J; Rzepka, Z; Wrześniok, D | 1 |
| Erdreich-Epstein, A; Fernandez, GE; Moats, RA; Pathania, AS; Ren, X; Shackleford, GM; Tran, A; Xu, J; Zhang, Y | 1 |
| DeLuca, JG; Herman, JA; Lee, E; Paddison, P; Pain, M; Toledo, CM; Wang, H; Yong, RL; Zhu, J | 1 |
| Gokturk, D; Ozdemir, MD | 1 |
| Brennum, J; Hamerlik, P; Jensen, KE; Michaelsen, SR; Pedersen, H; Poulsen, HS; Rasmussen, RD; Skjoth-Rasmussen, J; Staberg, M; Villingshøj, M; Vitting-Seerup, K | 1 |
| Deneen, B; Kfoury, N; McDonald, P; Mohila, CA; Qi, Z; Rockwell, N; Roy, A; Rubin, JB; Sun, T; Tinkum, KL; Warrington, NM; Weir, SJ; Yu, K | 1 |
| Ahmed, EM; Bandopadhyay, G; Coyle, B; Grabowska, A | 1 |
| He, X; Liang, P; Liu, Q; Liu, Z; Qian, Y; Wang, S; Wang, Z; Wu, B; Wu, H; Xu, Z; Zhu, R | 1 |
| Damiani, E; Doyle, AP; Solorio, JA; Wallace, HM | 1 |
| Chang, YH; Kuo, YC; Rajesh, R | 1 |
| Bettler, B; Gassmann, M; Tchorz, J; Tomé, M | 1 |
| Galita, G; Kopa, P; Macieja, A; Majsterek, I; Pastwa, E; Poplawski, T | 1 |
| Allhenn, D; Béduneau, A; Lamprecht, A; Neumann, D; Pellequer, Y | 1 |
| Biasoli, D; Borges, HL; Campanati, L; Chneiweiss, H; Cornélio, TA; Furtado, M; Kahn, SA; Moura-Neto, V | 1 |
| Arakawa, Y; Fujimoto, K; Kikuchi, T; Kunieda, T; Miyamoto, S; Mizowaki, T; Murata, D; Takagi, Y; Takahashi, JC | 1 |
| Amendolara, B; Bansal, M; Bruce, JN; Califano, A; Canoll, P; Carminucci, AS; Karan, C; Lei, L; Leung, R; Li, H; O, J; Realubit, R; Rothcock, R; Showers, C; Sonabend, AM; Yun, J | 1 |
| Habicht, KL; Khadeer, MA; Moaddel, R; Shimmo, R; Singh, NS; Wainer, IW | 1 |
| Azendorf, R; Eichler, M; Jahnke, HG; Krinke, D; Müller, A; Robitzki, AA; Schmidt, S | 1 |
| Escalon, E; Lollett, IV; Melnick, SJ; Quirin, KW; Ramachandran, C | 1 |
| Chen, YC; Kuo, YC | 1 |
| Kuo, YC; Lee, CH | 2 |
| Iwafuchi, H; Iwama, J; Kiyotani, C; Matsuoka, K; Morota, N; Ogiwara, H; Terashima, K | 1 |
| Kuo, YC; Wang, IH | 1 |
| Ge, H; Hu, L; Huang, J; Li, X; Lin, Z; Liu, Q; Pieper, RO; Shi, C; Wang, H; Wang, Z; Weng, C; Xu, J; Xu, X | 1 |
| Ceylan, S; Gokturk, D; Kelebek, H; Yilmaz, DM | 1 |
| Ashley, DM; Dobrovic, A; Drummond, KJ; Friedman, HS; Gan, HK; Hawkins, CJ; Johns, TG; Kaye, AH; Lovric, MM; Maxwell, JA; Mikeska, T; Riffkin, CD | 1 |
| Darzynkiewicz, Z; Kurose, A; Ogasawara, K; Ogawa, A; Sato, Y; Sawai, T; Traganos, F | 1 |
| Fukushima, T; Inoue, T; Komatsu, F; Ohmura, T; Ohta, M; Oshiro, S; Sakamoto, S; Tsugu, H | 1 |
| Aoki, T; Matsutani, M; Miyatake, S; Mizutani, T; Nojima, K; Nozaki, K; Okumura, R; Takagi, T; Takahashi, JA; Taki, W; Ueba, T; Yuba, Y | 1 |
| Brentrup, A; Frühwald, MC; Hasselblatt, M; Holling, M; Jeibmann, A; Niederstadt, T; Paulus, W; Pfister, S; Sträter, R | 1 |
| Feng, J; Guo, YJ; Jiang, XB; Jin, F; Shao, T; Wang, HT; Wei, YJ; Zhang, H; Zhang, SL; Zhao, HY; Zhao, L; Zhao, WJ | 1 |
| Dupre, S; Francesconi, AB; Hughes, BG; Lickliter, JD; Martin, D; Matos, M; Wyld, DK | 1 |
| Desjardins, A; Friedman, AH; Friedman, HS; Gururangan, S; Herndon, JE; Marcello, J; McLendon, R; Peters, K; Reardon, DA; Rich, JN; Sampson, J; Threatt, S; Vredenburgh, JJ | 1 |
| Bandopadhyay, G; Bowman, KJ; Braker, P; Coyle, B; Grundy, RG; Heath, R; Hussein, D; Jones, GD; Kerr, ID; Kumari, R; Lowe, J; Miller, S; Othman, R; Ottoman, R; Peet, A; Punjaruk, W; Rahman, R; Shaw, L; Storer, LC; Watson, S | 1 |
| Kanamori, M; Kumabe, T; Saito, R; Sonoda, Y; Tominaga, T; Yamashita, Y | 1 |
| Arima, R; Kuratsu, J; Makino, K; Nakamura, H; Ushio, Y | 1 |
| Cárcamo, JG; Garrido, W; Melo, R; Peigñan, L; Quezada, C; Rojas, D; San Martín, R; Segura, R | 1 |
| Bangert, A; Cristofanon, S; Debatin, KM; Fulda, S; Häcker, S | 1 |
| Bhat, K; Doucette, M; Gu, Y; Hsieh, TC; Kang, JX; Law, B; Liu, X; Qian, SY; Wang, F; Wong, ET; Wu, E; Zhou, S | 1 |
| McDonald, KL; Parkinson, JF; Sevim, H | 1 |
| Cheema, TA; Kanai, R; Kim, GW; Martuza, RL; Passer, B; Rabkin, SD; Wakimoto, H | 1 |
| Desjardins, A; Sampson, JH | 1 |
| Dosal, J; Handler, MZ; Kerdel, FA; Ricotti, CA; Tosti, A; Vega, J | 1 |
| Choi, KM; Gorospe, M; Hwang, SJ; Jeong, MR; Kim, HH; Masuda, K; Nam, DH; Park, YM | 1 |
| Escalon, E; Melnick, SJ; Nair, SM; Ramachandran, C | 1 |
| Anderluh, G; Assunção, Fdos S; Biasoli, D; de Souza, JM; Frauches, AC; Garcia, C; Geraldo, LH; Kahn, SA; Lima, FR; Moura-Neto, V; Pontes, B; Romão, L; Sobrinho, M; Soletti, RC; Tovar-Moll, F | 1 |
| Gnekow, A; Kuehl, J; Mölenkamp, G; Rating, D; Warmuth-Metz, M; Westphal, S; Wolff, JE | 1 |
| Bergamaschi, A; Cerella, C; Coletti, D; Ghibelli, L; Göhde, W; Perniconi, B; Tagliaferri, F; Teodori, L; Valente, MG | 1 |
| Fujiyama, Y; Kanaya, H; Kim, P; Watanabe, K | 1 |
| Houkin, K; Ichimiya, S; Kikuchi, T; Kondo, N; Momota, H; Sato, N; Torigoe, T; Yamaki, T | 1 |
| Chen, H; Farr-Jones, M; Fulton, D; Gulavita, S; Moore, R; Petruk, K; Roa, WH; Shaw, A; Th'ng, J | 1 |
| Baek, JH; Blake, M; Carrier, F; Kim, MS; Kohlhagen, G; Pommier, Y | 1 |
| Bottone, FG; Eling, TE; Ishibashi, M; Kamitani, H; Taniura, S; Watanabe, T | 1 |
| Kang, YH; Kim, SH; Lee, E; Lee, HJ; Lim, SJ; Park, YG; Youk, HJ | 1 |
| Amador, R; Aparicio, J; Beltrán, A; Calderero, V; Díaz, R; Jordá, MV; Reynés, G; Segura, A | 1 |
| De Maria, R; Eramo, A; Larocca, LM; Lotti, F; Pallini, R; Peschle, C; Pilozzi, E; Ricci-Vitiani, L; Sette, G; Zeuner, A | 1 |
| Cartron, PF; Cauquil, N; Gallenne, T; Gautier, F; Geneste, O; Grée, D; Grée, R; Juin, P; Manero, F; Vallette, FM | 1 |
| Kamei, M; Kawamura, A; Kohmura, E; Mizukawa, K; Sasaki, M; Sasayama, T; Tanaka, K | 1 |
| Addo-Yobo, SO; Donson, AM; Foreman, NK; Gore, L; Handler, MH | 1 |
| Benesch, M; Berthold, F; Gnekow, AK; Kortmann, RD; Pietsch, T; Rutkowski, S; Sträter, R; Wagner, S; Warmuth-Metz, M; Wolff, JE | 1 |
| Classen, CF; Papke, K; Trotter, A; Wagner, S; Warmuth-Metz, M; Wolff, JE | 1 |
| Bessette, B; Boda, C; Giraud, S; Jauberteau, MO; Lalloué, F; Mathonnet, M; Petit, D | 1 |
| Chen, ZP; Mu, YG; Sai, K; Shi, HL; Yue, WY; Zhang, JP; Zhang, XH | 1 |
| Ben Arush, MW; Eran, A; Guilburd, J; Postovsky, S; Vlodavsky, E | 1 |
| Chang, CC; Gondo, G; Hayashi, A; Ito, S; Kanno, H; Kyuma, Y; Nishimura, S; Ono, A; Sasaki, T; Sato, H; Shimizu, N; Tanaka, M; Yamamoto, I | 1 |
| Aguilera, D; Das, CM; Gopalakrishnan, V; Prasad, P; Vasquez, H; Wolff, JE; Zhang, M | 1 |
| Jiang, S; Lin, P; Ren, JJ; Wang, J; Wang, X; Wu, Y; Xiong, Z; Yang, H; Zhang, J | 1 |
| Balzarotti, M; Boiardi, A; Calatozzolo, C; Ciusani, E; Croci, D; de Grazia, U; Salmaggi, A | 1 |
| Kessinger, A | 1 |
| Hagiwara, Y; Hayakawa, T; Kanayama, T; Miyawaki, Y; Nakagawa, H; Tokiyoshi, K; Tsuruzono, K; Yamada, M | 1 |
| Kagawa, T; Konishi, S; Moritake, K; Nagai, H; Nagao, S; Yamasaki, T | 1 |
| Chang, TK; Hsien, YL; Hwang, B; Jeng, MJ; Tang, RB; Wong, TT | 1 |
| Brummett, RE; Dahlborg, SA; Dana, BW; Henner, WD; Neuwelt, EA; Roman-Goldstein, S; Tableman, M; Williams, PC | 1 |
| Barnett, GH; Hara, H; Kaakaji, R; Kondo, S; Kondo, Y; Morimura, T; Peterson, JW; Takeuchi, J | 1 |
| Ameri, A; Delattre, JY; Monjour, A; Poisson, M; Ronchin, P; Sahmoud, T; Sanson, M | 1 |
| de Tinguy-Moreaud, E; Denois, F; Lagarde, P; Montaudon, D; Pourquier, P; Robert, J | 1 |
| Kayama, T; Saino, M; Saito, S; Sakurada, K; Sato, K | 1 |
| Adams, G; Flynn, P; Grunnet, M; Hellman, R; Karp, D; Neuberg, DS; Robins, HI; Wagner, H | 1 |
| Abe, T; Cole, SP; Hori, S; Koike, K; Kuwano, M; Mori, T; Nakagawa, M; Wakabayashi, Y | 1 |
| Lauer, AK; Neuwelt, EA; Shults, WT; Wilson, MW; Wobig, JL | 1 |
| Boiardi, A; Broggi, G; Fariselli, L; Pozzi, A; Salmaggi, A; Silvani, A | 1 |
| Ciesielski, MJ; Fenstermaker, RA | 1 |
| Chowhan, N; Davis, R; Hentschel, P; Iliya, A; Madajewicz, S; Manzione, J; Meek, A; Roche, P; Roque, C; Shady, M; Tfayli, A | 1 |
| Boyett, JM; Finlay, JL; Grovas, AC; Lindsley, K; Rosenblum, M; Yates, AJ | 1 |
| Osmak, M; Skrk, J; Vrhovec, I | 1 |
| Bernard, EA; da Rocha, AB; Leyva, A; Logullo, AF; Mans, DR; Ruschel, C; Schwartsmann, G; Wetmore, LA | 1 |
| Kosteljanetz, M; Kristjansen, PE; Lassen, U; Poulsen, HS; Wagner, A | 1 |
| Atkins, H; Braun, A; Cabahug, C; Chowhan, N; Davis, R; Hentschel, P; Iliya, A; Madajewicz, S; Manzione, J; Meek, A; Roche, P; Roque, C; Shady, M; Tfayli, A; Wolf, W | 1 |
| Bondiau, PY; Chatel, M; Frenay, M; Lebrun, C; Lonjon, M | 1 |
| Cherrington, JM; Kabbinavar, F; Mann, E; Schwartz, DP; Shawver, LK; Slamon, DJ; Strawn, LM | 1 |
| Banno, Y; Nakashima, S; Nishimura, Y; Nozawa, Y; Sakai, N; Sawada, M; Shinoda, J; Takenaka, K; Yamakawa, H | 1 |
| Gnekow, A; Kortmann, RD; Kuehl, J; Mölenkamp, G; Pietsch, T; Westphal, S; Wolff, JE | 1 |
| Ikeda, J | 1 |
| Boynton, AL; Fan, Y; Gano, J; Hossain, MZ; Huang, R; Huang, RP | 1 |
| Aleksandrovic, J; Dagovic, A; Grujicic, D; Jeremic, B; Milicic, B; Nikolic, N; Shibamoto, Y; Stojanovic, M | 1 |
| Ashkenazi, E; Blass, M; Blumberg, PM; Brodie, C; Kazimirsky, G; Kronfeld, I; Lorenzo, PS; Mandil, R; Rosenthal, G; Umansky, F | 1 |
| Dieckmann, K; Schuller, E; Seidl, R; Slavc, I; Wandl, C | 1 |
| Berman, SA; Bursztajn, S; Feng, JJ; Nanda, A | 1 |
| Ashley, DM; Chow, CW; Gray, AZ; Hawkins, CJ; Riffkin, CD | 1 |
| Bello, L; Bikfalvi, A; Black, PM; Carrabba, G; Carroll, RS; Cerutti, F; Giussani, C; Landré, J; Lucini, V; Pluderi, M; Scaglione, F; Tomei, G; Villani, R | 1 |
| Dixon, JE; Donner, DB; Durden, DL; Mayo, LD; Tonks, NK | 1 |
| Bernaudin, JF; Declèves, X; Fajac, A; Hurbain, I; Laplanche, JL; Lehmann-Che, J; Mercier, C; Scherrmann, JM; Tardy, M | 1 |
| Djuric, L; Grujicic, D; Jeremic, B; Jevremovic, S; Mijatovic, L; Milojevic, L; Stanisavljevic, B | 1 |
| Boiardi, A; Botturi, M; Broggi, G; Milanesi, I; Munari, L; Silvani, A | 1 |
| Boiardi, A; Botturi, M; Milanesi, I; Munari, L; Silvani, A; Solero, CL | 1 |
| Alvarez, O; Beaton, R; Chowhan, N; Davis, R; Fertman, S; Iliya, A; Madajewicz, S; Meek, A; Pampati, M; Roque, C | 1 |
| August, C; Bayever, E; Finlay, JL; Freid, A; Kamani, N; Kramer, E; Packer, R; Rorke, L; Sutton, L; Zimmerman, R | 1 |
| Calogero, JA; Hellman, RM; Kaplan, BM | 1 |
| Castello, MA; Clerico, A; Deb, G; Dominici, C; Donfrancesco, A; Fidani, P | 1 |
1 review(s) available for etoposide and Astrocytoma, Grade IV
| Article | Year |
|---|---|
High dose chemotherapy with autologous bone marrow rescue for high grade gliomas of the brain: a potential for improvement in therapeutic results.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Brain Neoplasms; Carmustine; Combined Modality Therapy; Etoposide; Glioblastoma; Glioma; Humans; Lomustine; Teniposide | 1984 |
18 trial(s) available for etoposide and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Phase II study of ifosfamide, carboplatin, and etoposide in patients with a first recurrence of glioblastoma multiforme.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Disease Progression; Etoposide; Female; Glioblastoma; Humans; Ifosfamide; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Recurrence, Local; Quality of Life; Time Factors; Treatment Outcome; Young Adult | 2010 |
Phase II study of metronomic chemotherapy with bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Etoposide; Female; Glioblastoma; Humans; Kaplan-Meier Estimate; Karnofsky Performance Status; Male; Middle Aged; Neoplasm Recurrence, Local; Temozolomide | 2011 |
Treatment of paediatric pontine glioma with oral trophosphamide and etoposide.
Topics: Administration, Oral; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Child; Child, Preschool; Cyclophosphamide; Etoposide; Female; Glioblastoma; Glioma; Humans; Male; Pons; Postoperative Care; Survival Rate; Treatment Outcome | 2002 |
Combination chemotherapy using carboplatin (JM-8) and etoposide (JET therapy) for recurrent malignant gliomas: a phase II study.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carboplatin; Child; Child, Preschool; Etoposide; Female; Glioblastoma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Outcome Assessment, Health Care; Survival Rate | 2002 |
Neoadjuvant cisplatin and etoposide, with or without tamoxifen, prior to radiotherapy in high-grade gliomas: a single-center experience.
Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Cisplatin; Drug Administration Schedule; Etoposide; Female; Glioblastoma; Humans; Male; Middle Aged; Neoadjuvant Therapy; Survival Rate; Tamoxifen | 2005 |
Toxicity and efficacy of carboplatin and etoposide in conjunction with disruption of the blood-brain tumor barrier in the treatment of intracranial neoplasms.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; Carboplatin; Child; Etoposide; Female; Germinoma; Glioblastoma; Humans; Lymphoma; Male; Middle Aged; Neoplasm Metastasis; Neuroectodermal Tumors, Primitive; Oligodendroglioma; Tomography, X-Ray Computed | 1995 |
Treatment of recurrent malignant supratentorial gliomas with ifosfamide, carboplatin and etoposide: a phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Disease Progression; Etoposide; Female; Glioblastoma; Glioma; Humans; Ifosfamide; Male; Middle Aged; Neoplasm Recurrence, Local; Supratentorial Neoplasms; Survival Rate; Tomography, X-Ray Computed | 1996 |
A therapeutic trial of radiation therapy with Vincristine, etoposide, and Procarbazine (VVP) in high grade intracranial gliomas--an Eastern Cooperative Oncology Group Study (E2392).
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Combined Modality Therapy; Etoposide; Female; Glioblastoma; Glioma; Humans; Infusions, Intravenous; Male; Middle Aged; Procarbazine; Prognosis; Survival Analysis; Vincristine | 1998 |
Interstitial chemotherapy plus systemic chemotherapy for glioblastoma patients: improved survival in sequential studies.
Topics: Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Carmustine; Catheters, Indwelling; Cisplatin; Combined Modality Therapy; Etoposide; Glioblastoma; Humans; Postoperative Care; Survival Analysis | 1999 |
Regimen-related toxicity of myeloablative chemotherapy with BCNU, thiotepa, and etoposide followed by autologous stem cell rescue for children with newly diagnosed glioblastoma multiforme: report from the Children's Cancer Group.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Child; Child, Preschool; Combined Modality Therapy; Etoposide; Female; Glioblastoma; Hematopoietic Stem Cell Transplantation; Humans; Male; Pilot Projects; Survival Analysis; Thiotepa; Transplantation, Autologous | 1999 |
Treatment of newly diagnosed glioblastoma multiforme with carmustine, cisplatin and etoposide followed by radiotherapy. A phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cisplatin; Combined Modality Therapy; Disease Progression; Etoposide; Female; Glioblastoma; Humans; Male; Middle Aged; Radiotherapy; Survival Analysis | 1999 |
Therapy for patients with high grade astrocytoma using intraarterial chemotherapy and radiation therapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Combined Modality Therapy; Etoposide; Female; Glioblastoma; Humans; Injections, Intra-Arterial; Male; Middle Aged; Prospective Studies | 2000 |
Oral trofosfamide and etoposide in pediatric patients with glioblastoma multiforme.
Topics: Administration, Oral; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Stem Neoplasms; Child; Child, Preschool; Cyclophosphamide; Etoposide; Female; Glioblastoma; Humans; Male; Pilot Projects; Postoperative Care; Supratentorial Neoplasms; Survival Analysis; Treatment Outcome | 2000 |
Concurrent accelerated hyperfractionated radiation therapy and carboplatin/etoposide in patients with malignant glioma: long-term results of a phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carboplatin; Combined Modality Therapy; Dose Fractionation, Radiation; Etoposide; Female; Follow-Up Studies; Glioblastoma; Humans; Male; Middle Aged; Radiotherapy; Survival Rate; Time Factors | 2001 |
Carboplatin and etoposide chemotherapy regimen for recurrent malignant glioma: a phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Cisplatin; Drug Administration Schedule; Drug Evaluation; Drug Synergism; Etoposide; Female; Glioblastoma; Humans; Male; Middle Aged; Recurrence; Treatment Outcome | 1992 |
Local immunotherapy (beta-IFN) and systemic chemotherapy in primary glial tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Combined Modality Therapy; Etoposide; Glioblastoma; Humans; Immunotherapy; Interferon Type I; Middle Aged; Tomography, X-Ray Computed | 1991 |
Cisplatin and etoposide combination therapy for primary glial tumors: preliminary results.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Cisplatin; Combined Modality Therapy; Etoposide; Follow-Up Studies; Glioblastoma; Glioma; Humans; Middle Aged | 1991 |
High-dose multi-agent chemotherapy followed by bone marrow 'rescue' for malignant astrocytomas of childhood and adolescence.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Bone Marrow Transplantation; Brain Neoplasms; Carmustine; Child; Combined Modality Therapy; Etoposide; Female; Glioblastoma; Humans; Male; Spinal Cord Neoplasms; Thiotepa; Transplantation, Autologous | 1990 |
103 other study(ies) available for etoposide and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
Topics: Autophagy; Calcium Channel Blockers; Cell Line, Tumor; Drug Evaluation, Preclinical; Fluspirilene; Glioblastoma; Green Fluorescent Proteins; Humans; Intracellular Membranes; Loperamide; Microtubule-Associated Proteins; Mycotoxins; Peptides; Phagosomes; Phosphatidylinositol Phosphates; Pimozide; Protein Kinases; Recombinant Fusion Proteins; Sirolimus; Small Molecule Libraries; TOR Serine-Threonine Kinases; Trifluoperazine; Zinc Fingers | 2007 |
N⁴-Phenyl-substituted 2-acetylpyridine thiosemicarbazones: cytotoxicity against human tumor cells, structure-activity relationship studies and investigation on the mechanism of action.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Death; Cell Line, Tumor; Central Nervous System Neoplasms; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Etoposide; Female; Glioblastoma; Glioma; Humans; Inhibitory Concentration 50; Microtubules; Molecular Structure; Structure-Activity Relationship; Thiosemicarbazones; Tubulin; Tumor Suppressor Protein p53 | 2012 |
Discovery of potent and selective cytotoxic activity of new quinazoline-ureas against TMZ-resistant glioblastoma multiforme (GBM).
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Dose-Response Relationship, Drug; Drug Discovery; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Glioblastoma; Humans; Models, Molecular; Molecular Conformation; Quinazolines; Structure-Activity Relationship; Temozolomide; Urea | 2015 |
Chemosensitization of U-87 MG Glioblastoma Cells by Neobavaisoflavone towards Doxorubicin and Etoposide.
Topics: Doxorubicin; Etoposide; Glioblastoma; Humans; Isoflavones | 2022 |
Metabolomics Analysis Revealed Significant Metabolic Changes in Brain Cancer Cells Treated with Paclitaxel and/or Etoposide.
Topics: Brain Neoplasms; Etoposide; Glioblastoma; Humans; Paclitaxel; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2022 |
Inhibition of DNA-PK potentiates the synergistic effect of NK314 and etoposide combination on human glioblastoma cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Chromones; DNA-Activated Protein Kinase; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Inhibitors; Etoposide; Glioblastoma; Humans; Morpholines; Phenanthrenes | 2020 |
Molecular mechanisms of cell death induced in glioblastoma by experimental and antineoplastic drugs: New and old drugs induce apoptosis in glioblastoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Astrocytes; Caspases; Cell Line, Tumor; Cell Survival; Cisplatin; Etoposide; Glioblastoma; Humans; Leupeptins; Mice; Resveratrol; Tumor Suppressor Protein p53 | 2020 |
Ribosomal protein S11 influences glioma response to TOP2 poisons.
Topics: Apoptotic Protease-Activating Factor 1; Brain Neoplasms; Cell Line, Tumor; CRISPR-Cas Systems; DNA Breaks, Double-Stranded; DNA Repair; DNA Topoisomerases, Type II; Doxorubicin; Etoposide; Gene Knockout Techniques; Glioblastoma; Humans; Ribosomal Proteins; Topoisomerase II Inhibitors | 2020 |
Etoposide and olaparib polymer-coated nanoparticles within a bioadhesive sprayable hydrogel for post-surgical localised delivery to brain tumours.
Topics: Adhesiveness; Aerosols; Animals; Antineoplastic Agents; Brain; Brain Neoplasms; Drug Carriers; Drug Compounding; Drug Liberation; Etoposide; Glioblastoma; Humans; Hydrogels; Lactates; Male; Mice, Nude; Nanoparticles; Pectins; Phthalazines; Piperazines; Polyethylene Glycols; Rats; Solubility; Tissue Distribution | 2020 |
Focused Ultrasound-Mediated Blood-Brain Barrier Opening Increases Delivery and Efficacy of Etoposide for Glioblastoma Treatment.
Topics: Animals; Antineoplastic Agents, Phytogenic; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Chromatography, Liquid; Contrast Media; Disease Progression; Etoposide; Glioblastoma; Magnetic Resonance Imaging; Male; Mice; Microbubbles; Sonication; Tandem Mass Spectrometry; Ultrasonography, Interventional | 2021 |
Reimagining external beam radiotherapy for glioblastoma: "old beam, new trick".
Topics: Carmustine; Cytarabine; Etoposide; Glioblastoma; Humans | 2021 |
Effect of Paclitaxel/etoposide co-loaded polymeric nanoparticles on tumor size and survival rate in a rat model of glioblastoma.
Topics: Animals; Cell Line, Tumor; Drug Carriers; Etoposide; Glioblastoma; Nanoparticles; Paclitaxel; Polyethylene Glycols; Rats; Survival Rate | 2021 |
Neobavaisoflavone May Modulate the Activity of Topoisomerase Inhibitors towards U-87 MG Cells: An In Vitro Study.
Topics: Antibiotics, Antineoplastic; Astrocytes; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Doxorubicin; Etoposide; Glioblastoma; Glutathione; Humans; Irinotecan; Isoflavones; Plant Extracts; Psoralea; Signal Transduction; Topoisomerase II Inhibitors | 2021 |
PID1 increases chemotherapy-induced apoptosis in medulloblastoma and glioblastoma cells in a manner that involves NFκB.
Topics: Antineoplastic Agents; Apoptosis; Carrier Proteins; Cell Line, Tumor; Cisplatin; Etoposide; Glioblastoma; HEK293 Cells; Humans; Medulloblastoma; NF-kappa B | 2017 |
Sensitivity to
Topics: Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Brain Neoplasms; Camptothecin; Cell Cycle Proteins; Cell Line, Tumor; Etoposide; Gene Expression Profiling; Glioblastoma; Humans; Irinotecan; Protein Serine-Threonine Kinases; RNA, Messenger | 2017 |
The Effect of Rosmarinus Officinalis and Chemotherapeutic Etoposide on Glioblastoma (U87 MG) Cell Culture.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Etoposide; Glioblastoma; Humans; Mice; Plant Extracts; Rosmarinus | 2018 |
Targeting glioma stem-like cell survival and chemoresistance through inhibition of lysine-specific histone demethylase KDM2B.
Topics: Antineoplastic Agents; Apoptosis; Astrocytes; Brain Neoplasms; Cell Line; DNA Damage; Drug Resistance, Neoplasm; Etoposide; F-Box Proteins; Glioblastoma; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lomustine; Lysine; Neoplastic Stem Cells; Primary Cell Culture | 2018 |
Cooperative p16 and p21 action protects female astrocytes from transformation.
Topics: Animals; Astrocytes; Cell Cycle; Cell Survival; Cell Transformation, Neoplastic; Culture Media, Serum-Free; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Dose-Response Relationship, Drug; Embryo, Mammalian; Etoposide; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Glial Fibrillary Acidic Protein; Glioblastoma; Karyotyping; Male; Mice; Neurofibromin 1; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Pyridines; Retinoblastoma Protein; RNA, Messenger; Serum; Sex Characteristics; Transfection; Tumor Cells, Cultured | 2018 |
A HIF-independent, CD133-mediated mechanism of cisplatin resistance in glioblastoma cells.
Topics: AC133 Antigen; Basic Helix-Loop-Helix Transcription Factors; Brain Neoplasms; Cell Line, Tumor; Cisplatin; Dacarbazine; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; RNA, Messenger; Temozolomide; Tumor Hypoxia; Vascular Endothelial Growth Factors | 2018 |
Etoposide loaded layered double hydroxide nanoparticles reversing chemoresistance and eradicating human glioma stem cells in vitro and in vivo.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Carriers; Drug Resistance, Neoplasm; Etoposide; Glioblastoma; Humans; Hydroxides; Mice; Nanoparticles; Neoplastic Stem Cells; Phosphatidylinositol 3-Kinases; Xenograft Model Antitumor Assays | 2018 |
How reliable are in vitro IC
Topics: Antineoplastic Agents; Apoptosis; Biological Assay; Brain Neoplasms; Carboplatin; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Etoposide; Glioblastoma; Humans; Inhibitory Concentration 50; Necrosis; Neurons; Paraquat; Reproducibility of Results | 2019 |
Targeted delivery of etoposide, carmustine and doxorubicin to human glioblastoma cells using methoxy poly(ethylene glycol)‑poly(ε‑caprolactone) nanoparticles conjugated with wheat germ agglutinin and folic acid.
Topics: Cell Line, Tumor; Doxorubicin; Drug Delivery Systems; Etoposide; Folic Acid; Glioblastoma; Humans; Nanoparticles; Polyesters; Polyethylene Glycols; Wheat Germ Agglutinins | 2019 |
Constitutive activation of Notch2 signalling confers chemoresistance to neural stem cells via transactivation of fibroblast growth factor receptor-1.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Mice, Transgenic; Neural Stem Cells; Proto-Oncogene Proteins c-akt; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Notch2; Signal Transduction; Transcriptional Activation | 2019 |
Comparison of the effect of three different topoisomerase II inhibitors combined with cisplatin in human glioblastoma cells sensitized with double strand break repair inhibitors.
Topics: Apoptosis; Benzamides; Brain Neoplasms; Cannabidiol; Cell Cycle; Cell Line, Tumor; Chromones; Cisplatin; DNA Breaks, Double-Stranded; DNA Repair; Etoposide; Glioblastoma; Humans; Morpholines; Phenanthrenes; Sulfonamides; Topoisomerase II Inhibitors | 2019 |
A "drug cocktail" delivered by microspheres for the local treatment of rat glioblastoma.
Topics: Acridines; Animals; Antineoplastic Agents, Phytogenic; Celecoxib; Cyclooxygenase 2 Inhibitors; Drug Carriers; Etoposide; Glioblastoma; Lactic Acid; Male; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Pyrazoles; Rats; Rats, Inbred F344; Sulfonamides; Tetrahydroisoquinolines | 2013 |
Retinoblastoma protein regulates the crosstalk between autophagy and apoptosis, and favors glioblastoma resistance to etoposide.
Topics: Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; DNA Breaks, Double-Stranded; Drug Resistance, Neoplasm; Etoposide; Gene Knockdown Techniques; Glioblastoma; Humans; Neoplastic Stem Cells; Retinoblastoma Protein; RNA Interference; Tumor Suppressor Protein p53 | 2013 |
Retrospective analysis of bevacizumab in combination with ifosfamide, carboplatin, and etoposide in patients with second recurrence of glioblastoma.
Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Carboplatin; Combined Modality Therapy; Dacarbazine; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Glioblastoma; Hematologic Diseases; Humans; Ifosfamide; Interferons; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Recurrence, Local; Retrospective Studies; Salvage Therapy; Temozolomide; Treatment Outcome | 2013 |
Convection-enhanced delivery of etoposide is effective against murine proneural glioblastoma.
Topics: Animals; Antigens, Neoplasm; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Convection; Disease Models, Animal; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Delivery Systems; Etoposide; Glioblastoma; Humans; Mice; Poly-ADP-Ribose Binding Proteins; Survival Analysis; Topoisomerase II Inhibitors | 2014 |
Characterization of a multiple endogenously expressed adenosine triphosphate-binding cassette transporters using nuclear and cellular membrane affinity chromatography columns.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line, Tumor; Cell Membrane; Chromatography, Affinity; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Estrone; Etoposide; Glioblastoma; Humans; Ligands; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Nuclear Envelope; Prazosin; Protein Binding; Verapamil | 2014 |
A novel 96-well multielectrode array based impedimetric monitoring platform for comparative drug efficacy analysis on 2D and 3D brain tumor cultures.
Topics: Apoptosis; Biosensing Techniques; Brain Neoplasms; Cell Line, Tumor; Dielectric Spectroscopy; Doxorubicin; Etoposide; Glioblastoma; Humans; Spheroids, Cellular; Vincristine | 2015 |
Anticancer potential and mechanism of action of mango ginger (Curcuma amada Roxb.) supercritical CO₂ extract in human glioblastoma cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Carbon Dioxide; Cell Line, Tumor; Cell Survival; Curcuma; Dacarbazine; Etoposide; Glioblastoma; Humans; Mice; Plant Extracts; Reverse Transcriptase Polymerase Chain Reaction; Temozolomide | 2015 |
Targeting delivery of etoposide to inhibit the growth of human glioblastoma multiforme using lactoferrin- and folic acid-grafted poly(lactide-co-glycolide) nanoparticles.
Topics: Antineoplastic Agents, Phytogenic; Astrocytes; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Cells, Cultured; Drug Delivery Systems; Endothelial Cells; Etoposide; Folate Receptors, GPI-Anchored; Folic Acid; Glioblastoma; Humans; Lactic Acid; Lactoferrin; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Receptors, Cell Surface; Topoisomerase II Inhibitors | 2015 |
Inhibition against growth of glioblastoma multiforme in vitro using etoposide-loaded solid lipid nanoparticles with p-aminophenyl-α-D-manno-pyranoside and folic acid.
Topics: Antineoplastic Agents, Phytogenic; Cell Survival; Etoposide; Folic Acid; Glioblastoma; Humans; Lipids; Mannose; Nanoparticles | 2015 |
Neoadjuvant chemotherapy for brain tumors in infants and young children.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma; Carcinoma, Embryonal; Child; Child, Preschool; Choroid Plexus Neoplasms; Cisplatin; Cyclophosphamide; Drug Administration Schedule; Ependymoma; Etoposide; Female; Glioblastoma; Humans; Infant; Magnetic Resonance Imaging; Male; Neoadjuvant Therapy; Neuroectodermal Tumors, Primitive; Retrospective Studies; Rhabdoid Tumor; Second-Look Surgery; Treatment Outcome; Vincristine | 2015 |
Enhanced delivery of etoposide across the blood-brain barrier to restrain brain tumor growth using melanotransferrin antibody- and tamoxifen-conjugated solid lipid nanoparticles.
Topics: Antibodies, Monoclonal; Antineoplastic Agents, Phytogenic; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Drug Carriers; Etoposide; Glioblastoma; Humans; Membrane Glycoproteins; Nanoparticles; Permeability; Tamoxifen | 2016 |
Dual targeting of solid lipid nanoparticles grafted with 83-14 MAb and anti-EGF receptor for malignant brain tumor therapy.
Topics: Antineoplastic Agents, Phytogenic; Astrocytes; Blood-Brain Barrier; Brain Neoplasms; Capillaries; Cell Line; Cell Survival; Drug Delivery Systems; Electric Impedance; Endothelial Cells; ErbB Receptors; Etoposide; Glioblastoma; Humans; Nanoparticles; Particle Size | 2016 |
UBE2S, a novel substrate of Akt1, associates with Ku70 and regulates DNA repair and glioblastoma multiforme resistance to chemotherapy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biomarkers, Tumor; Cell Proliferation; DNA Damage; DNA Repair; Drug Resistance, Neoplasm; Etoposide; Female; Glioblastoma; Humans; Ku Autoantigen; Mice; Mice, Inbred BALB C; Mice, Nude; Phosphorylation; Proto-Oncogene Proteins c-akt; Tumor Cells, Cultured; Ubiquitin; Ubiquitin-Conjugating Enzymes; Xenograft Model Antitumor Assays | 2017 |
The Effect of Ascorbic Acid over the Etoposide- and Temozolomide-Mediated Cytotoxicity in Glioblastoma Cell Culture: A Molecular Study.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Central Nervous System Neoplasms; Dacarbazine; DNA Damage; Drug Synergism; Etoposide; Glioblastoma; Humans; Temozolomide | 2018 |
In vitro sensitivity testing of minimally passaged and uncultured gliomas with TRAIL and/or chemotherapy drugs.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Astrocytes; Carboplatin; Cell Line, Tumor; Cisplatin; Dacarbazine; Drug Screening Assays, Antitumor; Etoposide; Female; Glioblastoma; Glioma; Hepatocytes; Humans; Lomustine; Male; Membrane Glycoproteins; Middle Aged; Procarbazine; Recombinant Fusion Proteins; Temozolomide; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha; Vincristine | 2008 |
Diversity of DNA damage response of astrocytes and glioblastoma cell lines with various p53 status to treatment with etoposide and temozolomide.
Topics: Antineoplastic Agents; Apoptosis; Astrocytes; beta-Galactosidase; Cell Cycle; Cell Line, Tumor; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Dacarbazine; DNA Damage; Etoposide; Flow Cytometry; Fluorescent Antibody Technique; Glioblastoma; Histones; Humans; Immunohistochemistry; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Phosphorylation; Temozolomide; Time Factors; Tumor Suppressor Protein p53 | 2009 |
Efficacy of temozolomide treatment in patients with high-grade glioma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Chemotherapy, Adjuvant; Combined Modality Therapy; Dacarbazine; Etoposide; Female; Glioblastoma; Gliosarcoma; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Oligodendroglioma; Prognosis; Temozolomide; Treatment Outcome; Tumor Necrosis Factor-alpha | 2009 |
From glioblastoma to gangliocytoma: an unforeseen but welcome shift in biological behavior.
Topics: Antigens, Nuclear; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Brain Neoplasms; Carboplatin; Cell Differentiation; Cell Proliferation; Etoposide; Female; Ganglioneuroma; Glioblastoma; Humans; Hydrocephalus; Infant; Nerve Tissue Proteins; Neurofilament Proteins; Neurosurgical Procedures; Reverse Transcriptase Polymerase Chain Reaction; Synaptophysin | 2009 |
Influence of Etoposide on anti-apoptotic and multidrug resistance-associated protein genes in CD133 positive U251 glioblastoma stem-like cells.
Topics: AC133 Antigen; Adaptor Proteins, Signal Transducing; Antigens, CD; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Separation; Drug Resistance, Neoplasm; Etoposide; Flow Cytometry; Gene Expression; Genes, MDR; Glioblastoma; Glycoproteins; Humans; Inhibitor of Apoptosis Proteins; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Neoplastic Stem Cells; Peptides; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2010 |
Carboplatin and etoposide combined with bevacizumab for the treatment of recurrent glioblastoma multiforme.
Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Carboplatin; Disease-Free Survival; Etoposide; Female; Glioblastoma; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Recurrence, Local; Treatment Outcome | 2010 |
Pediatric brain tumor cancer stem cells: cell cycle dynamics, DNA repair, and etoposide extrusion.
Topics: Adolescent; Animals; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Cell Cycle; Child; Child, Preschool; Chromosome Aberrations; Comet Assay; DNA Repair; Drug Resistance, Neoplasm; Etoposide; Glioblastoma; Humans; Mice; Neoplasm Recurrence, Local; Neoplastic Stem Cells; Polymorphism, Single Nucleotide; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2011 |
[The safety of combination chemotherapy with ifosfamide, cisplatin, and etoposide (ICE): single-institution retrospective review of 108 cases].
Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Child, Preschool; Cisplatin; Ependymoma; Etoposide; Female; Glioblastoma; Hematologic Diseases; Humans; Ifosfamide; Infant; Male; Medulloblastoma; Middle Aged; Neoplasms, Germ Cell and Embryonal; Neuroectodermal Tumors, Primitive; Retrospective Studies | 2010 |
Therapy-associated secondary tumors in patients with non-germinomatous malignant germ cell tumors.
Topics: Adult; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Child; Child, Preschool; Chorionic Gonadotropin, beta Subunit, Human; Cisplatin; Combined Modality Therapy; Etoposide; Female; Glioblastoma; Hemangioma, Cavernous; Humans; Maintenance Chemotherapy; Male; Meningeal Neoplasms; Neoplasm, Residual; Neoplasms, Germ Cell and Embryonal; Neoplasms, Second Primary; Prognosis; Survival Rate; Young Adult | 2011 |
Combined use of anticancer drugs and an inhibitor of multiple drug resistance-associated protein-1 increases sensitivity and decreases survival of glioblastoma multiforme cells in vitro.
Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Child; Drug Therapy, Combination; Etoposide; Glioblastoma; Humans; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; RNA, Small Interfering; Vincristine | 2011 |
Chemosensitization of glioblastoma cells by the histone deacetylase inhibitor MS275.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Apoptosis; Benzamides; Blotting, Western; Cell Line, Tumor; Central Nervous System Neoplasms; Cisplatin; Dacarbazine; Doxorubicin; Drug Synergism; Etoposide; Glioblastoma; Histone Deacetylase Inhibitors; Histones; Humans; Microtubules; Pyridines; Temozolomide | 2011 |
Docosahexaenoic acid (DHA) sensitizes brain tumor cells to etoposide-induced apoptosis.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Carrier Proteins; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Damage; DNA Repair; Docosahexaenoic Acids; Drug Synergism; Etoposide; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Hyaluronan Receptors; Inhibitor of Apoptosis Proteins; Medulloblastoma; Mitogen-Activated Protein Kinase 14; NF-kappa B; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Survivin; Transcription Factors | 2011 |
Etoposide-mediated glioblastoma cell death: dependent or independent on the expression of its target, topoisomerase II alpha?
Topics: Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Cell Death; Cohort Studies; DNA Topoisomerases, Type II; DNA-Binding Proteins; Etoposide; Glioblastoma; Humans; Immunohistochemistry | 2011 |
Enhanced antitumor efficacy of low-dose Etoposide with oncolytic herpes simplex virus in human glioblastoma stem cell xenografts.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Camptothecin; Cell Cycle; Cell Line, Tumor; Combined Modality Therapy; Etoposide; Glioblastoma; Humans; Irinotecan; Mice; Mice, Nude; Neural Stem Cells; Oncolytic Virotherapy; Oncolytic Viruses; Simplexvirus; Topoisomerase I Inhibitors; Xenograft Model Antitumor Assays | 2011 |
Avastin: more questions than answers. . .
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Camptothecin; Chemoradiotherapy; Dacarbazine; Etoposide; Female; Glioblastoma; Glioma; Humans; Male; Neoplasm Recurrence, Local; Salvage Therapy; Supratentorial Neoplasms; Temozolomide | 2012 |
Ulceration of abdominal striae distensae (stretch marks) in a cancer patient.
Topics: Abdominal Wall; Adult; Antibodies, Antinuclear; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biopsy; Brain Neoplasms; Dexamethasone; Disease Progression; Drug Eruptions; Drug Interactions; Elastin; Etoposide; Fatal Outcome; Glioblastoma; Humans; Male; Neoplasm Staging; Ribonucleoproteins; Skin; Skin Ulcer; Striae Distensae | 2012 |
Heterogeneous nuclear ribonucleoprotein C1/C2 controls the metastatic potential of glioblastoma by regulating PDCD4.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Etoposide; Gene Expression Regulation, Neoplastic; Gene Silencing; Glioblastoma; Heterogeneous-Nuclear Ribonucleoprotein Group C; Humans; MicroRNAs; Neoplasm Invasiveness; Oncogene Protein v-akt; Ribosomal Protein S6 Kinases, 70-kDa; RNA-Binding Proteins | 2012 |
Potentiation of etoposide and temozolomide cytotoxicity by curcumin and turmeric force™ in brain tumor cell lines.
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cerebellar Neoplasms; Curcuma; Curcumin; Dacarbazine; Dose-Response Relationship, Drug; Drug Synergism; Etoposide; Glioblastoma; Humans; Inhibitory Concentration 50; Medulloblastoma; Phytotherapy; Plant Extracts; Plants, Medicinal; Rhizome; Temozolomide | 2012 |
Equinatoxin II potentiates temozolomide- and etoposide-induced glioblastoma cell death.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Cnidarian Venoms; Dacarbazine; Drug Synergism; Etoposide; Glioblastoma; Humans; Immunohistochemistry; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Temozolomide | 2012 |
Static magnetic fields affect calcium fluxes and inhibit stress-induced apoptosis in human glioblastoma cells.
Topics: Apoptosis; Calcium; Etoposide; Flow Cytometry; Glioblastoma; Heat-Shock Response; Humans; Magnetics; Tumor Cells, Cultured | 2002 |
Histone H2AX sensitizes glioma cells to genotoxic stimuli by recruiting DNA double-strand break repair proteins.
Topics: Antineoplastic Agents, Phytogenic; Brain Neoplasms; BRCA1 Protein; Cell Cycle Proteins; Cell Division; DNA Damage; DNA Repair; DNA, Neoplasm; Etoposide; G2 Phase; Glioblastoma; Histones; Humans; Mitosis; Mutagenicity Tests; Nuclear Proteins; Tumor Cells, Cultured; Up-Regulation; X-Rays | 2003 |
X-linked inhibitor regulating TRAIL-induced apoptosis in chemoresistant human primary glioblastoma cells.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Carrier Proteins; Caspase 3; Caspase 9; Caspases; Cell Line, Tumor; Cell Survival; Cisplatin; Cytochromes c; Cytosol; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Etoposide; Glioblastoma; Humans; Intracellular Signaling Peptides and Proteins; Microscopy, Confocal; Mitochondria; Mitochondrial Proteins; Proteins; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha; X-Linked Inhibitor of Apoptosis Protein | 2003 |
Inhibition of histone deacetylase increases cytotoxicity to anticancer drugs targeting DNA.
Topics: Acetylation; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; DNA Topoisomerases, Type II; DNA, Neoplasm; Drug Synergism; Enzyme Inhibitors; Etoposide; Gene Expression; Glioblastoma; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Tumor Suppressor Protein p53; Vorinostat | 2003 |
The cyclooxygenase inhibitor indomethacin modulates gene expression and represses the extracellular matrix protein laminin gamma1 in human glioblastoma cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Blotting, Western; Cell Line, Tumor; Cyclooxygenase Inhibitors; Densitometry; Dose-Response Relationship, Drug; Etoposide; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Indomethacin; Kinetics; Laminin; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; Sulindac | 2005 |
Potentiation by alpha-tocopheryl succinate of the etoposide response in multidrug resistance protein 1-expressing glioblastoma cells.
Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Drug Synergism; Etoposide; Glioblastoma; Glutathione; Humans; Liposomes; Vitamin E | 2005 |
Chemotherapy resistance of glioblastoma stem cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cisplatin; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Glioblastoma; Humans; Jurkat Cells; Mice; Mice, Nude; Neoplastic Stem Cells; Time Factors; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2006 |
The small organic compound HA14-1 prevents Bcl-2 interaction with Bax to sensitize malignant glioma cells to induction of cell death.
Topics: Amino Acid Sequence; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-2-Associated X Protein; Benzopyrans; Combined Modality Therapy; DNA Damage; Drug Synergism; Etoposide; Female; Glioblastoma; Humans; Mice; Mice, Nude; Molecular Sequence Data; Nitriles; Proto-Oncogene Proteins c-bcl-2; Xenograft Model Antitumor Assays | 2006 |
Synthetic Smac peptide enhances the effect of etoposide-induced apoptosis in human glioblastoma cell lines.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Brain Neoplasms; Caspases; Cell Line, Tumor; DNA Fragmentation; Drug Synergism; Etoposide; Glioblastoma; Humans; Intracellular Signaling Peptides and Proteins; Mitochondrial Proteins; Recombinant Proteins | 2006 |
MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Child; Child, Preschool; Dacarbazine; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; DNA, Neoplasm; Drug Resistance, Neoplasm; Etoposide; Gene Silencing; Glioblastoma; Humans; Kaplan-Meier Estimate; Neoplasm Proteins; Retrospective Studies; Temozolomide; Treatment Outcome; Tumor Suppressor Proteins | 2007 |
Secondary dissemination in children with high-grade malignant gliomas and diffuse intrinsic pontine gliomas.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Brain Stem Neoplasms; Cerebellar Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Etoposide; Female; Glioblastoma; Glioma; Humans; Infant; Kaplan-Meier Estimate; Male; Meningeal Neoplasms; Pons; Radiotherapy; Retrospective Studies; Treatment Outcome; Vincristine | 2006 |
Late response to radiochemotherapy in pediatric glioblastoma: report on two patients treated according to HIT-GBM protocols.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Stem Neoplasms; Child; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Craniotomy; Disease Progression; Etoposide; Fatal Outcome; Follow-Up Studies; Glioblastoma; Humans; Ifosfamide; Male; Randomized Controlled Trials as Topic; Remission Induction; Supratentorial Neoplasms; Time Factors; Treatment Outcome; Vincristine | 2006 |
In vitro apoptotic induction of human glioblastoma cells by Fas ligand plus etoposide and in vivo antitumour activity of combined drugs in xenografted nude rats.
Topics: Animals; Apoptosis; Cell Line, Tumor; Etoposide; Fas Ligand Protein; Glioblastoma; Humans; Male; Rats; Rats, Nude; Transplantation, Heterologous | 2007 |
[Individualized chemotherapy based on drug sensitivity and resistance assay and MGMT protein expression for patients with malignant glioma--analysis of 42 cases].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Child; Cisplatin; Dacarbazine; Drug Resistance, Neoplasm; Etoposide; Female; Gene Expression Regulation, Neoplastic; Glioblastoma; Glioma; Humans; Male; Middle Aged; Nausea; Neutropenia; O(6)-Methylguanine-DNA Methyltransferase; Remission Induction; Temozolomide; Young Adult | 2006 |
Secondary glioblastoma multiforme after treatment for primary choroid plexus carcinoma in childhood.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Choroid Plexus Neoplasms; Cisplatin; Combined Modality Therapy; Diagnosis, Differential; Etoposide; Fatal Outcome; Glioblastoma; Humans; Male; Neoplasms, Second Primary; Vincristine | 2007 |
Collagen gel matrix assay as an in vitro chemosensitivity test for malignant astrocytic tumors.
Topics: Adult; Aged; Antineoplastic Agents; Astrocytoma; Carboplatin; Central Nervous System Neoplasms; Cisplatin; Collagen; Disease Progression; Disease-Free Survival; Drug Screening Assays, Antitumor; Etoposide; Female; Fibrin Foam; Follow-Up Studies; Glioblastoma; Humans; Japan; Karnofsky Performance Status; Male; Middle Aged; Nimustine; Sensitivity and Specificity; Survival Analysis; Tissue Adhesives; Treatment Outcome; Tumor Burden; Tumor Cells, Cultured | 2007 |
Valproic acid induces p21 and topoisomerase-II (alpha/beta) expression and synergistically enhances etoposide cytotoxicity in human glioblastoma cell lines.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; DNA Topoisomerases, Type II; Drug Synergism; Enzyme Inhibitors; Etoposide; Gene Expression Regulation, Neoplastic; Glioblastoma; Histone Deacetylase Inhibitors; Histones; Humans; Isoenzymes; Valproic Acid | 2007 |
Establishment of a new human glioblastoma multiforme cell line (WJ1) and its partial characterization.
Topics: Abietanes; Adult; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Cell Culture Techniques; Cell Division; Cell Line, Tumor; Cisplatin; Etoposide; Glial Fibrillary Acidic Protein; Glioblastoma; Humans; Intermediate Filament Proteins; Karyotyping; Male; Mice; Mice, Nude; Nerve Tissue Proteins; Nestin; Phenanthrenes; Xenograft Model Antitumor Assays | 2007 |
Valproic acid increases the in vitro effects of nitrosureas on human glioma cell lines.
Topics: Acetylation; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Astrocytoma; Carmustine; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Drug Synergism; Etoposide; Glioblastoma; Humans; Mitoxantrone; Valproic Acid | 2007 |
Myelin basic protein in the cerebrospinal fluid of patients with brain tumors.
Topics: Adult; Aged; Astrocytoma; Biomarkers, Tumor; Brain Damage, Chronic; Brain Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Etoposide; Female; Follow-Up Studies; Glioblastoma; Humans; Infusions, Intra-Arterial; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Male; Meningeal Neoplasms; Meningioma; Middle Aged; Myelin Basic Protein; Treatment Outcome | 1994 |
[The efficacy of granisetron as a prophylactic anti-emetic agent used in conjunction with MCNU and VP16 chemotherapeutic regimens in the management of a pediatric case of hypothalamic anaplastic astrocytoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Etoposide; Glioblastoma; Granisetron; Humans; Hypothalamic Neoplasms; Interferon-beta; Male; Nausea; Nitrosourea Compounds; Vomiting | 1995 |
Preirradiation chemotherapy for very young children with brain tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Cerebellar Neoplasms; Chemotherapy, Adjuvant; Child, Preschool; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Ependymoma; Etoposide; Female; Follow-Up Studies; Glioblastoma; Humans; Infant; Male; Medulloblastoma; Neurologic Examination; Vinblastine | 1993 |
mdm2 gene mediates the expression of mdr1 gene and P-glycoprotein in a human glioblastoma cell line.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Doxorubicin; Drug Resistance, Multiple; Etoposide; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Nuclear Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Tumor Cells, Cultured | 1996 |
Differential stabilization of topoisomerase-II-DNA cleavable complexes by doxorubicin and etoposide in doxorubicin-resistant rat glioblastoma cells.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; DNA; DNA Damage; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance, Neoplasm; Enzyme Stability; Etoposide; Glioblastoma; Rats; Tumor Cells, Cultured; Verapamil | 1997 |
[A case of infantile anaplastic astrocytoma treated with surgery and chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Drug Administration Schedule; Etoposide; Female; Frontal Lobe; Glioblastoma; Humans; Infant; Parietal Lobe; Remission Induction | 1997 |
Expression of multidrug resistance protein gene in patients with glioma after chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Northern; Child; Doxorubicin; Etoposide; Female; Gene Expression Regulation, Neoplastic; Genes, MDR; Glioblastoma; Humans; Male; Middle Aged; Nimustine; RNA, Messenger; RNA, Neoplasm; Vincristine | 1998 |
Severe ocular and orbital toxicity after intracarotid etoposide phosphate and carboplatin therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Carotid Artery, Internal; Etoposide; Eye Diseases; Glioblastoma; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Orbital Diseases; Organophosphorus Compounds; Tomography, X-Ray Computed | 1999 |
Synergistic cytotoxicity, apoptosis and protein-linked DNA breakage by etoposide and camptothecin in human U87 glioma cells: dependence on tyrosine phosphorylation.
Topics: Brain Neoplasms; Camptothecin; Cell Survival; Colonic Neoplasms; DNA Damage; Drug Synergism; Etoposide; Glioblastoma; Glioma; Humans; Mitotic Index; Phosphotyrosine; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1999 |
Toxicities related to intraarterial infusion of cisplatin and etoposide in patients with brain tumors.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Cisplatin; Etoposide; Female; Glioblastoma; Hematoma; Humans; Infusions, Intra-Arterial; Lymphoma; Male; Middle Aged; Nausea; Retrospective Studies; Vomiting | 1999 |
Cisplatin resistant glioblastoma cells may have increased concentration of urokinase plasminogen activator and plasminogen activator inhibitor type 1.
Topics: Antineoplastic Agents; Brain Neoplasms; Cell Division; Cell Survival; Cisplatin; Doxorubicin; Drug Resistance, Neoplasm; Enzyme-Linked Immunosorbent Assay; Etoposide; Glioblastoma; Humans; Kinetics; Plasminogen Activator Inhibitor 1; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator; Vincristine | 1999 |
Tamoxifen inhibits particulate-associated protein kinase C activity, and sensitises cultured human glioblastoma cells not to etoposide but to gamma-radiation and BCNU.
Topics: Antineoplastic Agents; Carmustine; Cell Division; Drug Synergism; Etoposide; Gamma Rays; Glioblastoma; Humans; Immunohistochemistry; Protein Kinase C; Receptors, Estrogen; Tamoxifen; Transforming Growth Factor beta; Tumor Cells, Cultured | 1999 |
Up-front chemotherapy with fotemustine (F) / cisplatin (CDDP) / etoposide (VP16) regimen in the treatment of 33 non-removable glioblastomas.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Etoposide; Female; France; Glioblastoma; Humans; Male; Middle Aged; Neoadjuvant Therapy; Nitrosourea Compounds; Organophosphorus Compounds; Survival Rate; Treatment Outcome | 2000 |
Effects of SU101 in combination with cytotoxic agents on the growth of subcutaneous tumor xenografts.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cell Division; Cell Survival; Cisplatin; Etoposide; Glioblastoma; Head and Neck Neoplasms; Humans; Isoxazoles; Leflunomide; Lung Neoplasms; Mice; Mice, Nude; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2000 |
Influence of Bax or Bcl-2 overexpression on the ceramide-dependent apoptotic pathway in glioma cells.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Brain Neoplasms; Caspases; Ceramides; Cisplatin; Culture Media, Serum-Free; Cytochrome c Group; Enzyme Activation; Etoposide; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Glioblastoma; Glioma; Humans; Mitochondria; Neoplasm Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Recombinant Fusion Proteins; Sphingomyelin Phosphodiesterase; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2000 |
[Roles of p53 in chemotherapy of glioblastoma].
Topics: Antineoplastic Agents; Apoptosis; Cell Line; Cisplatin; Etoposide; Flow Cytometry; Glioblastoma; Nimustine; Paclitaxel; Polymerase Chain Reaction; Temperature; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2000 |
Connexin 43 (cx43) enhances chemotherapy-induced apoptosis in human glioblastoma cells.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Survival; Connexin 43; Drug Interactions; Etoposide; Flow Cytometry; Fluorescent Dyes; G2 Phase; Gap Junctions; Gene Expression Regulation; Glioblastoma; Humans; In Situ Nick-End Labeling; Isoquinolines; Proto-Oncogene Proteins c-bcl-2; Transfection; Tumor Cells, Cultured | 2001 |
Protein kinase Calpha and protein kinase Cdelta play opposite roles in the proliferation and apoptosis of glioma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Astrocytoma; Brain Neoplasms; Caspases; Cell Division; Drug Resistance, Neoplasm; Etoposide; Glial Fibrillary Acidic Protein; Glioblastoma; Humans; Isoenzymes; Middle Aged; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Protein Structure, Tertiary; Recombinant Fusion Proteins; Signal Transduction; Tumor Cells, Cultured | 2001 |
Prolonged second response to cisplatin, etoposide, and ifosfamide in a child with a recurrent brainstem glioblastoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Stem Neoplasms; Child; Cisplatin; Etoposide; Female; Glioblastoma; Humans; Ifosfamide; Magnetic Resonance Imaging; Recurrence; Remission Induction; Salvage Therapy; Time Factors; Treatment Outcome | 2001 |
Differential responses of human neuroblastoma and glioblastoma to apoptosis.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Membrane; Cell Survival; Cytosol; DNA Fragmentation; Enzyme Inhibitors; Etoposide; Glioblastoma; Humans; L-Lactate Dehydrogenase; Neuroblastoma; Poly(ADP-ribose) Polymerases; Protein Kinase C; Staurosporine; Tumor Cells, Cultured | 2001 |
Ex vivo pediatric brain tumors express Fas (CD95) and FasL (CD95L) and are resistant to apoptosis induction.
Topics: Adolescent; Animals; Antineoplastic Agents; Apoptosis; Astrocytoma; Brain Neoplasms; Cell Survival; Child; Child, Preschool; Colorimetry; Culture Media, Conditioned; DNA, Complementary; Drug Resistance, Neoplasm; Etoposide; Fas Ligand Protein; fas Receptor; Female; Ganglioglioma; Germinoma; Glioblastoma; Humans; Infant; Jurkat Cells; Male; Medulloblastoma; Membrane Glycoproteins; Mice; Neoplasm Proteins; Neuroblastoma; Neuroectodermal Tumors, Primitive; Pineal Gland; Pinealoma; Recombinant Fusion Proteins; Transfection; Tumor Cells, Cultured | 2001 |
Low-dose chemotherapy combined with an antiangiogenic drug reduces human glioma growth in vivo.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Cell Division; Dose-Response Relationship, Drug; Etoposide; Glioblastoma; Humans; Male; Matrix Metalloproteinase 2; Mice; Mice, Nude; Neovascularization, Pathologic; Peptide Fragments; Recombinant Proteins; Xenograft Model Antitumor Assays | 2001 |
PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy.
Topics: Blotting, Western; Cell Cycle; Cell Line; Cell Nucleus; Cloning, Molecular; Coloring Agents; Cytoplasm; DNA Damage; Dose-Response Relationship, Drug; Down-Regulation; Etoposide; Genes, Reporter; Glioblastoma; Humans; Microscopy, Confocal; Mutation; Neoplasms; Nuclear Proteins; Phosphoric Monoester Hydrolases; Precipitin Tests; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; PTEN Phosphohydrolase; Retroviridae; Signal Transduction; Tetrazolium Salts; Thiazoles; Transcription, Genetic; Transduction, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2002 |
Molecular and functional MDR1-Pgp and MRPs expression in human glioblastoma multiforme cell lines.
Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Brain Neoplasms; Etoposide; Female; Glial Fibrillary Acidic Protein; Glioblastoma; Humans; Immunohistochemistry; Male; Middle Aged; Multidrug Resistance-Associated Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Tumor Cells, Cultured; Vincristine | 2002 |
Intracarotid chemotherapy with etoposide and cisplatin for malignant brain tumors.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carotid Arteries; Cisplatin; Combined Modality Therapy; Etoposide; Female; Glioblastoma; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Radiotherapy Dosage | 1991 |
VP-16, vincristine and procarbazine with radiation therapy for treatment of malignant brain tumors.
Topics: Adult; Aged; Astrocytoma; Brain Neoplasms; Combined Modality Therapy; Etoposide; Female; Glioblastoma; Humans; Male; Middle Aged; Procarbazine; Vincristine | 1990 |
High-dose carboplatin in combination with etoposide (JET regimen) for childhood brain tumors.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Bone Marrow Diseases; Brain Neoplasms; Carboplatin; Child; Child, Preschool; Drug Evaluation; Etoposide; Glioblastoma; Hearing Loss, Sensorineural; Humans; Infant; Medulloblastoma; Remission Induction | 1990 |