Page last updated: 2024-08-23

etoposide and Acute Promyelocytic Leukemia

etoposide has been researched along with Acute Promyelocytic Leukemia in 92 studies

Research

Studies (92)

TimeframeStudies, this research(%)All Research%
pre-19905 (5.43)18.7374
1990's46 (50.00)18.2507
2000's28 (30.43)29.6817
2010's12 (13.04)24.3611
2020's1 (1.09)2.80

Authors

AuthorsStudies
Chen, AY; Cheng, CC; Chou, TC; Dong, Q; Liu, DF; Liu, LF; Luo, YL; Savaraj, N; Yu, C1
Aguirre, A; Becerra, A; Faúndez, MA; Morales, V; Quintero, C; Rojas, RS; Valderrama, M1
Liao, M; Yu, J1
Bax, B; Fenner, S; Hann, M; Infante Lara, L; Isidro-Llobet, A; Osheroff, N; Ratcliffe, S1
Creutzig, U; Dworzak, MN; Reinhardt, D; Ritter, J; Schellong, G; Zimmermann, M1
Miyawaki, S1
Su, Y; Zhang, L; Zhang, R; Zhou, X1
Iland, HJ; Seymour, JF; Wei, A1
Avvisati, G; Breccia, M; Carmosino, I; Chisini, M; Cimino, G; Colafigli, G; Finsinger, P; Foà, R; Girmenia, C; Latagliata, R; Lo-Coco, F; Minotti, C; Montagna, C; Petti, MC; Romano, A; Volpicelli, P; Vozella, F1
Kojima, Y; Shimokawa, T1
Chen, J; Dong, L; Gu, LJ; Jiang, H; Pan, C; Tang, JY; Wang, YP; Xue, HL; Ye, QD; Zhou, M1
Adami, F; Aversa, SM; Canova, F; Di Bona, E; Marino, D; Salvagno, L; Sorarů, M; Trentin, C1
Enomoto, R; Hirano, H; Koshiba, C; Lee, E1
Cao, F; Gilbert, GE; Heegaard, CW; Hou, J; Rasmussen, JT; Shi, J; Zhang, Y; Zhou, J1
Ozdemirli, M; Sathiyamoorthy, S; Shad, A1
Bai, QX; Chen, XQ; Gao, GX; Gu, HT; Liang, R; Shu, MM; Wang, WQ; Wang, YW; Yang, L; Zhang, T; Zhang, YQ; Zhu, HF1
Borutinskaitė, VV; Magnusson, KE; Matuzevičius, D; Navakauskas, D; Navakauskienė, R; Treigytė, G1
Baran, J; Bukowska-Straková, K; Krzysciak, W; Papiez, MA1
Corcos, L; Logette, E; Solary, E; Solier, S; Wotawa, A1
Au, WY; Chim, CS; Chung, LP; Kwong, YL; Ma, SK1
Kondo, T; Mikami, M; Nakanishi, H; Otsuki, T; Suemori, S; Suetsugu, Y; Sugihara, T; Tsujioka, T; Wada, H; Yamamori, S1
Fouillard, L; Frassoni, F; Gorin, NC; Labopin, M; Meloni, G; Polge, E1
Adès, L; Blair, IA; Cassinat, B; Chomienne, C; Cross, NC; Felix, CA; Fenaux, P; Grimwade, D; Lafage-Pochitaloff, M; Mason, A; Mistry, AR; Osheroff, N; Parry, A; Peniket, AJ; Reiter, A; Segal, MR; Solomon, E; Walz, C; Whitmarsh, RJ; Wiemels, JL1
Avvisati, G; Breccia, M; Capria, S; Cimino, G; Diverio, D; Latagliata, R; Meloni, G; Petti, MC1
Cedrone, M; Chierichini, A; Diverio, D; Foà, R; Lo Coco, F; Mariani, G; Pasquini, L; Pelosi, E; Peschle, C; Riccioni, R; Rossini, A; Saulle, E; Testa, U; Vitale, A1
Mochiduki, Y; Muramoto, S1
Forrest, DL; Hogge, DE; Lavoie, JC; Nantel, SH; Nevil, TJ; Savoie, ML; Shepherd, JD; Smith, CA; Song, KW; Sutherland, HJ; Toze, CL1
Miyoshi, N; Noda, M1
Brandalise, SR; Matsuda, EI; Nowill, AE; Oliveira, SN; Rodrigues, PC; Viana, MB; Yunes, JA1
Gilbert, GE; Heegaard, CW; Rasmussen, JT; Shi, J; Shi, Y; Waehrens, LN1
Alvarez, C; Bolufer, P; Brunet, S; Colomer, D; Díaz-Mediavilla, J; Escoda, L; Esteve, J; González San Miguel, JD; González, M; Martín, G; Rivas, C; Rubio, V; Sánchez Godoy, P; Sanz, MA; Sayas, MJ; Tomás, JF; Tormo, M1
Debski, R; Grzanka, A; Grzanka, D; Smolinski, D; Stepien, A; Zuryn, A1
Enomoto, R; Hirano, H; Lee, E; Maeda, K; Miyauchi, A; Ohashi, T; Ohno, M; Sugahara, C; Suzuki, C; Tanimoto, E; Yokoi, T1
Arai, A; Fukuda, T; Jinta, M; Koyama, T; Miu, T; Miura, O; Murakami, N; Sakashita, C; Yamamoto, K1
Ates, H; Pehlivan, M; Sercan, HO; Sercan, Z; Simsek, O1
Akiyama, Y; Bessho, R; Furusho, K; Kataoka, A; Kubota, M; Lin, YW; Okuda, A; Usami, I; Wakazono, Y1
Amadori, S; Avvisati, G; Cedrone, M; Cimino, G; Mancini, F; Mandelli, F; Moleti, ML; Testi, AM; Todisco, E1
Archim-Baud, E; Castaigne, S; Chastang, C; Chomienne, C; Degos, L; Fenaux, P; Fey, M; Link, H; Löwenberg, B; Sanz, M1
Egeler, RM1
Kohn, KW; O'Connor, PM; Pommier, Y; Shimizu, T1
Azuno, Y; Fujita, N; Kaku, K; Kaneko, T; Matsumoto, N; Okubo, M1
Castel, V; Esquembre, C; Ferris, J; López-Andreu, JA; Verdeguer, A1
Igarashi, Y; Ishiyama, K; Kumagai, H; Sasaki, H; Satoh, S; Yahagi, A1
Inamitsu, T; Ishii, E; Matsuzaki, A; Nagotoshi, Y; Ohga, S; Suda, M; Tasaka, H; Ueda, K; Watanabe, T1
Castel, V; Esquembre, C; Ferrís, J; Lopez-Andrew, JA; Senent, ML; Verdeguer, A1
Bessho, R; Hirota, H; Kawai, M; Kubota, M; Kuwakado, K; Lin, YW; Matsubara, K; Nishikomori, R; Okuda, A; Wakazono, Y1
Corey, SJ; Gollin, SM; Locker, J; Oliveri, DR; Penchansky, L; Redner, RL; Shekhter-Levin, S1
Cortes, JE; Estey, E; Hirsh-Ginsberg, C; Kantarjian, H; Keating, M; Koller, C; O'Brien, S; Robertson, LE; Stass, S1
Macfarlane, DE; O'Donnell, PS1
Fukushima, T; Inuzuka, M; Liu, YP; Nakamura, T; Takauji, R; Ueda, T; Yoshida, A1
Egi, S; Horibe, K; Katayama, I; Kitabayashi, T; Matsushita, T; Miyajima, Y; Numata, S; Sekiguchi, N; Yanai, M1
Davidson, NE; Desnoyers, S; Kaufmann, SH; Ottaviano, Y; Poirier, GG1
Bertrand, R; Kohn, KW; Pommier, Y; Solary, E1
Barry, MA; Eastman, A; Reynolds, JE1
Biersack, H; Boege, F; Gieseler, F; Meyer, P2
Balitrand, N; Barbey, S; Calabresse, C; Chomienne, C; Degos, L; Fenaux, P; Venturini, L1
Cooper, GM; Erhardt, P1
Nakamura, T; Ueda, T; Yoshida, A1
Kakihara, T; Kataoka, S; Kishi, K; Okada, R; Tanaka, A; Uchiyama, M; Watanabe, A; Yamamoto, K1
Gonzalez-Gonzalez, A; Pinilla, J; Requena, A; Velasco, JG1
Horibe, K; Kudo, K; Naoe, T; Ohno, R; Yoshida, H1
Aller, P; de Blas, E; García-Bermejo, L; Pérez, C; Vilaboa, NE1
Amarante-Mendes, GP; Bhalla, K; Green, DR; Huang, Y; Liu, L; Naekyung Kim, C; Perkins, CL1
Horibe, K; Kiyoi, H; Kudo, K; Naoe, T; Numata, S; Yoshida, H1
Bernasconi, C; Castagnola, C; Corso, A; Dabusti, M; Lazzarino, M; Lunghi, M; Tajana, M; Zappasodi, P1
Lindsay, GS; Wallace, HM1
Chillón, C; García, JL; González, M; Gutiérrez, NC; Hernández, JM; Muntión, S1
de Camargo, B; Lopes, LF1
Camera, A; Catalano, L; Picardi, M; Rotoli, B; Selleri, C1
Buonaiuto, MR; De Renzo, A; Luciano, L; Notaro, R; Pane, F; Rotoli, B; Santoro, LF1
Mollee, PN; Rodwell, R; Taylor, D; Taylor, KM; Williams, B1
Bishop, JF; Bradstock, KF; Cobcroft, R; Eliadis, P; Enno, A; Gill, D; Herrmann, RP; Juneja, S; Lowenthal, RM; Manoharan, A; Matthews, JP; Page, FJ; Rooney, KF; Rosenfeld, D; Seldon, M; Taylor, KM; Wolf, MM; Young, GA1
Daniel, TO; Koury, MJ; Kravtsov, VD1
Berthou, C; Buzyn, A; Cahn, JY; Chomienne, C; Cordonnier, C; de Revel, T; Degos, L; Dombret, H; Fegueux, N; Fenaux, P; Gardin, C; Gratecos, N; Guerci, A; Huguet, F; Kotoucek, P; Maloisel, F; Naccache, P; Pigneux, A; Reman, O; Sadoun, A; Stamatoullas, A; Thomas, X; Travade, P; Vekhoff, A; Vilque, JP1
Avvisati, G; Barbui, T; Bernasconi, C; Bolufer, P; Colomer, D; Díaz-Mediavilla, J; Esteve, J; Ferrara, F; Fioritoni, G; González, JD; Gonzalez, M; Liso, V; Lo Coco, F; Mandelli, F; Martín, G; Petti, MC; Rayón, C; Ribera, JM; Rodeghiero, F; Sanz, MA1
Castello, MA; Maurizi, P; Schiavetti, A; Varrasso, G1
Biamonti, G; Denegri, M; Donzelli, M; Montecucco, A; Rossi, R; Scovassi, A1
Kakishita, E; Mori, A; Okada, M; Okamoto, T; Takatsuka, H; Wakae, T1
Ballard, ET; Huang, FS; Stern, LE; Warner, BW; Zwerdling, T1
Autexier, C; Dupuis, S; Moriarty, TJ1
Mitchell, DC; Win, N1
Elliott, S; Marlton, P; Meagher, D; Rodwell, R; Taylor, D; Taylor, K; Timms, P; White, S; Wiley, J; Wright, S1
Kaufmann, SH1
Costello, C; McCarthy, D; Mir, N; Nadir, F; Rule, S; Samson, D; Taylor, J1
Bertrand, R; Jenkin, J; Kerrigan, D; Pommier, Y; Sarang, M1
Andersson, BS; Ling, YH; Nelson, JA1
Akiyama, Y; Hashimoto, H; Kitoh, T; Kubota, M; Mikawa, H; Shimizu, T; Takimoto, T; Tanizawa, A1
Beran, M; Blick, M; Chan, D; Hinds, M; Mayes, J; Parker, E; Radcliffe, A; Sie, KL; Silberman, L; Zwelling, LA1
Politi, PM; Sinha, BK1
Akahoshi, Y; Asou, N; Fujimoto, K; Fukuda, S; Ishimaru, S; Kawano, F; Murai, C; Sawatari, T; Taen, A; Takatsuki, K1
Blick, M; Chan, D; Hinds, M; Mayes, J; Silberman, LE; Zwelling, LA1

Reviews

9 review(s) available for etoposide and Acute Promyelocytic Leukemia

ArticleYear
Development of a curative treatment within the AML-BFM studies.
    Klinische Padiatrie, 2013, Volume: 225 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Etoposide; Germany; Humans; Idarubicin; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Methotrexate; Multicenter Studies as Topic; Prednisone; Randomized Controlled Trials as Topic; Survival Rate; Thioguanine; Vincristine

2013
[Current therapy for acute myeloid leukemia and acute promyelocytic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014, Volume: 55, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Drug Discovery; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Maintenance Chemotherapy; Mercaptopurine; Methotrexate; Molecular Targeted Therapy; Mutation; Recurrence; Tretinoin; Vincristine

2014
[Report of a case with secondary acute promyelocytic leukemia after therapy for hemophagocytic lymphohistiocytosis and review of literature].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2013, Volume: 51, Issue:12

    Topics: Acute Disease; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Daunorubicin; Epstein-Barr Virus Infections; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Lymphohistiocytosis, Hemophagocytic; Male; Neoplasms, Second Primary; Risk Assessment; Treatment Outcome; Tretinoin

2013
Have all-trans retinoic acid and arsenic trioxide replaced all-trans retinoic acid and anthracyclines in APL as standard of care.
    Best practice & research. Clinical haematology, 2014, Volume: 27, Issue:1

    Topics: Adult; Age Factors; Aged; Anthracyclines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Blood Coagulation Factors; Clinical Trials as Topic; Combined Modality Therapy; Cytarabine; Etoposide; Humans; Hydroxyurea; Idarubicin; Leukemia, Promyelocytic, Acute; Maintenance Chemotherapy; Middle Aged; Mitoxantrone; Multicenter Studies as Topic; Oxides; Platelet Transfusion; Practice Guidelines as Topic; Remission Induction; Risk Assessment; Thioguanine; Treatment Outcome; Tretinoin

2014
[Acute promyelocytic leukemia associated with hemophagocytic syndrome].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2007, Volume: 48, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Disseminated Intravascular Coagulation; Etoposide; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Lymphohistiocytosis, Hemophagocytic; Male; Pancytopenia; Treatment Outcome; Tretinoin

2007
Treatment of newly diagnosed acute promyelocytic leukemia (APL) by all transretinoic acid (ATRA) combined with chemotherapy: The European experience. European APL Group.
    Leukemia & lymphoma, 1995, Volume: 16, Issue:5-6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cell Differentiation; China; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Europe; Humans; Immunologic Factors; Leukemia, Promyelocytic, Acute; Leukocytosis; Life Tables; Middle Aged; Mitoxantrone; New York; Pilot Projects; Remission Induction; Survival Rate; Treatment Outcome; Tretinoin

1995
Acute promyelocytic leukaemia in a patient treated with etoposide for Langerhans cell histiocytosis.
    British journal of haematology, 1994, Volume: 86, Issue:4

    Topics: Child; Child, Preschool; Etoposide; Female; Histiocytosis, Langerhans-Cell; Humans; Infant; Leukemia, Promyelocytic, Acute

1994
Secondary acute promyelocytic leukemia in a child treated with epipodophyllotoxins.
    The American journal of pediatric hematology/oncology, 1994, Volume: 16, Issue:4

    Topics: Bone Neoplasms; Child; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Male; Neoplasms, Second Primary; Pelvic Bones; Sarcoma, Ewing; Teniposide

1994
Etoposide-related acute promyelocytic leukemia.
    Leukemia, 1998, Volume: 12, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Base Sequence; Child; Child, Preschool; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Etoposide; Female; Humans; Infant; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Molecular Sequence Data; Neoplasm Proteins; Neoplasms, Second Primary; Oncogene Proteins, Fusion; Topoisomerase II Inhibitors

1998

Trials

6 trial(s) available for etoposide and Acute Promyelocytic Leukemia

ArticleYear
BAVC regimen and autologous bone marrow transplantation for APL patients in second molecular remission: updated results.
    Bone marrow transplantation, 2005, Volume: 36, Issue:1

    Topics: Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Child; Cytarabine; Etoposide; Female; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Remission Induction; Salvage Therapy; Transplantation, Autologous

2005
Outcome of patients with acute promyelocytic leukemia failing to front-line treatment with all-trans retinoic acid and anthracycline-based chemotherapy (PETHEMA protocols LPA96 and LPA99): benefit of an early intervention.
    Leukemia, 2007, Volume: 21, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Kaplan-Meier Estimate; Leukemia, Promyelocytic, Acute; Liposomes; Male; Middle Aged; Mitoxantrone; Neoplasm, Residual; Oncogene Proteins, Fusion; Prognosis; Recurrence; Remission Induction; Salvage Therapy; Survival Analysis; Time Factors; Treatment Outcome; Tretinoin

2007
Treatment of newly diagnosed acute promyelocytic leukemia (APL) by all transretinoic acid (ATRA) combined with chemotherapy: The European experience. European APL Group.
    Leukemia & lymphoma, 1995, Volume: 16, Issue:5-6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cell Differentiation; China; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Europe; Humans; Immunologic Factors; Leukemia, Promyelocytic, Acute; Leukocytosis; Life Tables; Middle Aged; Mitoxantrone; New York; Pilot Projects; Remission Induction; Survival Rate; Treatment Outcome; Tretinoin

1995
All-trans retinoic acid followed by chemotherapy for salvage of refractory or relapsed acute promyelocytic leukemia.
    Cancer, 1994, Jun-15, Volume: 73, Issue:12

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Drug Administration Schedule; Etoposide; Female; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Mitoxantrone; Remission Induction; Salvage Therapy; Tretinoin

1994
A phase I/II study of intensive dose escalation of cytarabine in combination with idarubicin and etoposide in induction and consolidation treatment of adult acute myeloid leukemia. Australian Leukaemia Study Group (ALSG).
    Leukemia & lymphoma, 1999, Volume: 34, Issue:5-6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Cytarabine; Disease-Free Survival; Dose-Response Relationship, Drug; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Remission Induction; Survival Rate

1999
Definition of relapse risk and role of nonanthracycline drugs for consolidation in patients with acute promyelocytic leukemia: a joint study of the PETHEMA and GIMEMA cooperative groups.
    Blood, 2000, Aug-15, Volume: 96, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Cytarabine; Etoposide; Female; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Mitoxantrone; Multivariate Analysis; Predictive Value of Tests; Recurrence; Risk; Thioguanine; Tretinoin

2000

Other Studies

78 other study(ies) available for etoposide and Acute Promyelocytic Leukemia

ArticleYear
Design of antineoplastic agents on the basis of the "2-phenylnaphthalene-type" structural pattern. 2. Synthesis and biological activity studies of benzo]b]naphtho[2,3-d]furan-6,11-dione derivatives.
    Journal of medicinal chemistry, 1993, Dec-10, Volume: 36, Issue:25

    Topics: Antineoplastic Agents; Carcinoma, Small Cell; Cisplatin; DNA Topoisomerases, Type II; Furans; Humans; Leukemia, Promyelocytic, Acute; Naphthoquinones; Structure-Activity Relationship; Tumor Cells, Cultured

1993
Synthesis of 4(3H)quinazolinimines with selective cytotoxic effect on human acute promyelocytic leukemia cells.
    Bioorganic & medicinal chemistry, 2017, 05-15, Volume: 25, Issue:10

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Oxidative Stress; Quinazolinones; Structure-Activity Relationship

2017
Secondary Leukemia in a Patient With EBV-HLH Carrying Heterozygous STXBP2 Variant.
    Journal of pediatric hematology/oncology, 2022, Mar-01, Volume: 44, Issue:2

    Topics: Child, Preschool; Epstein-Barr Virus Infections; Etoposide; Herpesvirus 4, Human; Humans; Leukemia, Promyelocytic, Acute; Lymphohistiocytosis, Hemophagocytic; Male; Munc18 Proteins

2022
Coupling the core of the anticancer drug etoposide to an oligonucleotide induces topoisomerase II-mediated cleavage at specific DNA sequences.
    Nucleic acids research, 2018, 03-16, Volume: 46, Issue:5

    Topics: Antineoplastic Agents; Base Sequence; DNA Cleavage; DNA Topoisomerases, Type II; Etoposide; Feasibility Studies; Humans; Leukemia, Promyelocytic, Acute; Oligonucleotides; Oncogene Proteins, Fusion; Topoisomerase II Inhibitors

2018
Acute promyelocytic leukemia in patients aged >70 years: the cure beyond the age.
    Annals of hematology, 2015, Volume: 94, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Follow-Up Studies; Humans; Idarubicin; Interferon-alpha; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Mitoxantrone; Remission Induction; Survival Analysis; Time Factors; Treatment Outcome; Tretinoin

2015
[Gemtuzumab ozogamicin successfully induced molecular remission in relapsed therapy-related acute promyelocytic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2008, Volume: 49, Issue:4

    Topics: Adult; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Etoposide; Female; Gemtuzumab; Humans; Leukemia, Promyelocytic, Acute; Remission Induction

2008
[Effectiveness of the AML-XH-99-M3 protocol for treatment of acute promyelocytic leukemia in children].
    Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2008, Volume: 10, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Infant; Leukemia, Promyelocytic, Acute; Male; Tretinoin

2008
Acute promyelocytic leukemia after Stanford V plus radiotherapy for advanced Hodgkin lymphoma.
    Leukemia & lymphoma, 2009, Volume: 50, Issue:7

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Doxorubicin; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Hodgkin Disease; Humans; Leukemia, Promyelocytic, Acute; Mechlorethamine; Neoplasms, Radiation-Induced; Prednisone; Remission Induction; Treatment Outcome; Vinblastine; Vincristine

2009
Inhibition of P-glycoprotein by wogonin is involved with the potentiation of etoposide-induced apoptosis in cancer cells.
    Annals of the New York Academy of Sciences, 2009, Volume: 1171

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Dose-Response Relationship, Drug; Drug Synergism; Drugs, Chinese Herbal; Etoposide; Flavanones; Flow Cytometry; HL-60 Cells; Humans; In Situ Nick-End Labeling; Leukemia, Promyelocytic, Acute

2009
Phosphatidylserine exposure and procoagulant activity in acute promyelocytic leukemia.
    Journal of thrombosis and haemostasis : JTH, 2010, Volume: 8, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Blood Coagulation; Blood Coagulation Tests; Cell Differentiation; Cell Line, Tumor; Cell Membrane; Cell Survival; Daunorubicin; Etoposide; Factor Xa; Female; Flow Cytometry; Humans; Leukemia, Promyelocytic, Acute; Male; Membrane Glycoproteins; Microscopy, Confocal; Milk Proteins; Oxides; Phosphatidylserines; Thrombin; Thromboplastin; Tretinoin; Young Adult

2010
Acute promyelocytic leukemia following chemotherapy for EBV-associated hemophagocytic lymphohistiocytosis.
    Pediatric blood & cancer, 2011, Volume: 56, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cyclosporine; Dexamethasone; Epstein-Barr Virus Infections; Etoposide; Herpesvirus 4, Human; Humans; In Situ Hybridization, Fluorescence; Infant; Karyotyping; Leukemia, Promyelocytic, Acute; Lymphatic Diseases; Lymphohistiocytosis, Hemophagocytic; Male; Oncogene Proteins, Fusion; Translocation, Genetic

2011
Reduced tumor lysis syndrome with low dose chemotherapy for hyperleukocytic acute leukemia prior to induction therapy.
    Asian Pacific journal of cancer prevention : APJCP, 2011, Volume: 12, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cytarabine; Etoposide; Female; Humans; Induction Chemotherapy; Leukemia, Promyelocytic, Acute; Leukostasis; Male; Middle Aged; Retrospective Studies; Treatment Outcome; Tumor Lysis Syndrome; Young Adult

2011
Alpha-Dystrobrevin and its associated proteins in human promyelocytic leukemia cells induced to apoptosis.
    Journal of proteomics, 2012, Jun-18, Volume: 75, Issue:11

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Dystrophin-Associated Proteins; Etoposide; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Neoplasm Proteins; Oligopeptides

2012
(-)-Epicatechin enhances etoposide-induced antileukaemic effect in rats with acute myeloid leukaemia.
    Anticancer research, 2012, Volume: 32, Issue:7

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bone Marrow Cells; Catechin; Drug Synergism; Etoposide; Fluorescence Recovery After Photobleaching; Leukemia, Promyelocytic, Acute; Lipid Peroxidation; Male; Malondialdehyde; Organ Size; Rats; Rats, Inbred BN; Spleen; Superoxide Dismutase

2012
Differential influence of etoposide on two caspase-2 mRNA isoforms in leukemic cells.
    Cancer letters, 2002, Nov-28, Volume: 185, Issue:2

    Topics: Alternative Splicing; Apoptosis; Apoptosis Regulatory Proteins; Caspase 2; Caspases; Cysteine Endopeptidases; Dactinomycin; Enzyme Induction; Enzyme Precursors; Etoposide; Exons; Gene Expression Regulation, Leukemic; Genes, bcl-2; HL-60 Cells; Humans; Leukemia, Monocytic, Acute; Leukemia, Promyelocytic, Acute; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Protein Biosynthesis; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogenes; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; U937 Cells

2002
Two cases of therapy-related acute promyelocytic leukemia (t-APL) after mantle cell lymphoma and gestational trophoblastic disease.
    Annals of hematology, 2002, Volume: 81, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Arsenic Trioxide; Arsenicals; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Leukemia, Promyelocytic, Acute; Lymphoma, Mantle-Cell; Male; Neoplasms, Second Primary; Oxides; Pregnancy; Tretinoin

2002
MLL/AF-1p fusion in therapy-related early pre-B acute lymphoblastic leukemia with t(1;11)(p32;q23) translocation developing in the relapse phase of acute promyelocytic leukemia.
    International journal of hematology, 2003, Volume: 78, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 11; Cytarabine; Daunorubicin; Enzyme Inhibitors; Etoposide; Fatal Outcome; Humans; Idarubicin; In Situ Hybridization, Fluorescence; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Mitoxantrone; Myeloid-Lymphoid Leukemia Protein; Neoplasm Proteins; Neoplasms, Second Primary; Oncogene Proteins, Fusion; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Topoisomerase II Inhibitors; Translocation, Genetic; Tretinoin

2003
Comparison of BAVC to BuCy regimens in autologous stem cell transplantation for adult patients with acute myeloid leukemia.
    Haematologica, 2004, Volume: 89, Issue:1

    Topics: Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Carmustine; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Drug Combinations; Etoposide; Female; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Retrospective Studies; Stem Cell Transplantation; Transplantation, Autologous

2004
DNA topoisomerase II in therapy-related acute promyelocytic leukemia.
    The New England journal of medicine, 2005, Apr-14, Volume: 352, Issue:15

    Topics: Antineoplastic Agents; DNA Damage; DNA Repair; DNA Topoisomerases, Type II; DNA, Neoplasm; Doxorubicin; Etoposide; Humans; In Vitro Techniques; Leukemia, Promyelocytic, Acute; Mitoxantrone; Neoplasms, Second Primary; Polymerase Chain Reaction; Sequence Analysis, DNA; Topoisomerase II Inhibitors; Translocation, Genetic

2005
TRAIL decoy receptors mediate resistance of acute myeloid leukemia cells to TRAIL.
    Haematologica, 2005, Volume: 90, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 8; Cell Differentiation; Cell Membrane; Cytarabine; Drug Resistance, Neoplasm; Etoposide; Female; GPI-Linked Proteins; Granulocytes; HL-60 Cells; Humans; Hydroxyurea; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Monocytes; Oncogene Proteins, Fusion; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Member 10c; Recombinant Fusion Proteins; Tretinoin; Tumor Cells, Cultured; Tumor Necrosis Factor Decoy Receptors; Tumor Stem Cell Assay; U937 Cells

2005
[Therapy-related acute promyelocytic leukemia with a t(9;22)(q34;q11) and t(15;17)(q22;q11 to approximately 12) subclone].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2005, Volume: 46, Issue:11

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 22; Chromosomes, Human, Pair 9; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Karyotyping; Leukemia, Promyelocytic, Acute; Prednisolone; Remission Induction; Translocation, Genetic; Tretinoin; Vincristine

2005
Shifting to outpatient management of acute myeloid leukemia: a prospective experience.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cyclophosphamide; Cytarabine; Daunorubicin; Etoposide; Feasibility Studies; Female; Humans; Inpatients; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Outpatients; Patient Discharge; Patient Readmission; Prospective Studies; Remission Induction; Survival Rate; Treatment Outcome

2006
[Complication of topoisomerase II inhibitor-related acute promyelocytic leukemia with t(1;10) (q21;q26) in a patient with Sézary syndrome].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2006, Volume: 47, Issue:5

    Topics: Aged; Antineoplastic Agents, Phytogenic; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Male; Nucleic Acid Synthesis Inhibitors; Sezary Syndrome; Skin Neoplasms

2006
Prognostic significance of WT1 gene expression in pediatric acute myeloid leukemia.
    Pediatric blood & cancer, 2007, Volume: 49, Issue:2

    Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brazil; Child; Child, Preschool; Chromosome Inversion; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Daunorubicin; Etoposide; Female; Follow-Up Studies; Gene Expression Regulation, Leukemic; Genes, Wilms Tumor; Humans; Infant; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Male; Neoplasm Proteins; Prognosis; Proportional Hazards Models; Reverse Transcriptase Polymerase Chain Reaction; Survival Analysis; Translocation, Genetic; WT1 Proteins

2007
Lactadherin detects early phosphatidylserine exposure on immortalized leukemia cells undergoing programmed cell death.
    Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2006, Dec-01, Volume: 69, Issue:12

    Topics: Annexin A5; Antigens, Surface; Apoptosis; Etoposide; Flow Cytometry; Fluorescent Dyes; HL-60 Cells; Humans; K562 Cells; Leukemia, Erythroblastic, Acute; Leukemia, Promyelocytic, Acute; Microscopy, Confocal; Milk Proteins; Phosphatidylserines

2006
Expression of cyclin A in human leukemia cell line HL-60 following treatment with doxorubicin and etoposide: the potential involvement of cyclin A in apoptosis.
    Oncology reports, 2007, Volume: 17, Issue:5

    Topics: Apoptosis; Cell Division; Cyclin A; Doxorubicin; Etoposide; Flow Cytometry; G2 Phase; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute

2007
Wogonin, a plant flavone, potentiates etoposide-induced apoptosis in cancer cells.
    Annals of the New York Academy of Sciences, 2007, Volume: 1095

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Drug Synergism; Etoposide; Flavanones; HL-60 Cells; Humans; Jurkat Cells; Leukemia, Promyelocytic, Acute; Leukemia, T-Cell; Rats; Scutellaria

2007
Induction of apoptosis increases expression of non-canonical WNT genes in myeloid leukemia cell lines.
    Oncology reports, 2007, Volume: 18, Issue:6

    Topics: Antineoplastic Agents; Benzamides; Caspase 3; Cell Line, Tumor; Cyclin D1; Etoposide; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Piperazines; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Wnt Proteins

2007
Selection and partial characterization of calcium ionophore (A23187) resistant cells.
    Biochemical and biophysical research communications, 1995, Aug-15, Volume: 213, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Calcimycin; Calcium; Cell Division; Cytarabine; DNA; Drug Resistance; Etoposide; Flow Cytometry; Humans; Ionomycin; Leukemia, Promyelocytic, Acute; Terpenes; Thapsigargin; Tumor Cells, Cultured; Ultraviolet Rays

1995
Therapy-related acute myelomonocytic leukemia following successful treatment for acute promyelocytic leukemia.
    Leukemia, 1995, Volume: 9, Issue:9

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 10; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cytarabine; Etoposide; Female; Humans; Idarubicin; Karyotyping; Leukemia, Myelomonocytic, Acute; Leukemia, Promyelocytic, Acute; Mercaptopurine; Methotrexate; Mitoxantrone; Neoplasms, Second Primary; Remission Induction; Thioguanine; Translocation, Genetic

1995
Acute promyelocytic leukemia with t(15;17) abnormality after chemotherapy containing etoposide for Langerhans cell histiocytosis.
    Cancer, 1995, Jan-01, Volume: 75, Issue:1

    Topics: Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Registries; Translocation, Genetic

1995
Unscheduled activation of cyclin B1/Cdc2 kinase in human promyelocytic leukemia cell line HL60 cells undergoing apoptosis induced by DNA damage.
    Cancer research, 1995, Jan-15, Volume: 55, Issue:2

    Topics: Aphidicolin; Apoptosis; Camptothecin; CDC2 Protein Kinase; Cyclins; DNA Damage; Enzyme Activation; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Mechlorethamine; Phosphorylation; S Phase; Tumor Cells, Cultured

1995
Mitoxantrone and etoposide in breast milk.
    American journal of hematology, 1995, Volume: 48, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Etoposide; Female; Humans; Leukemia, Promyelocytic, Acute; Milk, Human; Mitoxantrone; Pregnancy; Pregnancy Complications, Neoplastic

1995
Acute promyelocytic leukemia with t(15;17) abnormality after chemotherapy containing etoposide for Langerhans' cell histiocytosis.
    Cancer, 1994, Sep-01, Volume: 74, Issue:5

    Topics: Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Etoposide; Histiocytosis, Langerhans-Cell; Humans; Leukemia, Promyelocytic, Acute; Translocation, Genetic

1994
Flow cytometric analysis of the cell cycle of the leukemic cell lines treated with etoposide and cytosine arabinoside.
    The Tohoku journal of experimental medicine, 1994, Volume: 174, Issue:2

    Topics: Bromodeoxyuridine; Cell Cycle; Cell Division; Cytarabine; DNA Replication; DNA, Neoplasm; Etoposide; Flow Cytometry; Humans; Leukemia, Monocytic, Acute; Leukemia, Promyelocytic, Acute; Tumor Cells, Cultured

1994
Pyrrolidine dithiocarbamate, a potent inhibitor of nuclear factor kappa B (NF-kappa B) activation, prevents apoptosis in human promyelocytic leukemia HL-60 cells and thymocytes.
    Biochemical pharmacology, 1994, Nov-16, Volume: 48, Issue:10

    Topics: Acetylcysteine; Apoptosis; Base Sequence; Cytarabine; Endonucleases; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; NF-kappa B; Oligodeoxyribonucleotides; Phenanthrolines; Pyrrolidines; T-Lymphocytes; Thiocarbamates; Thymus Gland; Tumor Cells, Cultured

1994
A non-classical translocation involving 17q12 (retinoic acid receptor alpha) in acute promyelocytic leukemia (APML) with atypical features.
    Leukemia, 1994, Volume: 8, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Child, Preschool; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Karyotyping; Leukemia, Promyelocytic, Acute; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Thioguanine; Translocation, Genetic

1994
Phorbol ester induces apoptosis in HL-60 promyelocytic leukemia cells but not in HL-60 PET mutant.
    Leukemia, 1993, Volume: 7, Issue:11

    Topics: Apoptosis; Calcimycin; DNA Damage; DNA, Neoplasm; Drug Tolerance; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Mutation; Novobiocin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Role of calcium ion in induction of apoptosis by etoposide in human leukemia HL-60 cells.
    Biochemical and biophysical research communications, 1993, Oct-29, Volume: 196, Issue:2

    Topics: Apoptosis; Calcium; Cell Line; Chelating Agents; DNA Damage; DNA, Neoplasm; Egtazic Acid; Etoposide; Fluorescent Dyes; Fura-2; Humans; Leukemia, Promyelocytic, Acute; Tumor Cells, Cultured

1993
Acute promyelocytic leukemia with t(15;17) abnormality after chemotherapy containing etoposide for Langerhans cell histiocytosis.
    Cancer, 1993, Dec-15, Volume: 72, Issue:12

    Topics: Child, Preschool; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Etoposide; Female; Histiocytosis, Langerhans-Cell; Humans; Infant; Leukemia, Promyelocytic, Acute; Translocation, Genetic

1993
Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis.
    Cancer research, 1993, Sep-01, Volume: 53, Issue:17

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Etoposide; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Molecular Weight; NAD; Peptide Fragments; Poly(ADP-ribose) Polymerases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protease Inhibitors

1993
Differential induction of apoptosis in undifferentiated and differentiated HL-60 cells by DNA topoisomerase I and II inhibitors.
    Blood, 1993, Mar-01, Volume: 81, Issue:5

    Topics: Amsacrine; Apoptosis; Camptothecin; Cell Differentiation; DNA; DNA Damage; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Tetradecanoylphorbol Acetate; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tretinoin; Tumor Cells, Cultured

1993
Etoposide-induced apoptosis in human HL-60 cells is associated with intracellular acidification.
    Cancer research, 1993, May-15, Volume: 53, Issue:10 Suppl

    Topics: Apoptosis; Calcium; Cell Cycle; Cell Death; Cell Separation; DNA, Neoplasm; Endonucleases; Enzyme Activation; Etoposide; Flow Cytometry; Humans; Hydrogen-Ion Concentration; Intracellular Fluid; Leukemia, Promyelocytic, Acute; Tumor Cells, Cultured

1993
Different functional states of topoisomerase II can be discriminated by orthovanadate sensitivity in multi-drug resistant human leukemic cells.
    Leukemia & lymphoma, 1993, Volume: 9, Issue:4-5

    Topics: Adenosine Triphosphate; Allosteric Site; Amsacrine; Chromatography, Ion Exchange; Clone Cells; DNA Topoisomerases, Type II; Drug Resistance; Etoposide; Humans; Isoenzymes; Leukemia, Promyelocytic, Acute; Molecular Weight; Neoplasm Proteins; Neoplastic Stem Cells; Point Mutation; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Vanadates

1993
In vitro treatment with retinoids or the topoisomerase inhibitor, VP-16, evidences different functional apoptotic pathways in acute promyelocytic leukemic cells.
    Leukemia, 1995, Volume: 9, Issue:12

    Topics: Apoptosis; Enzyme Inhibitors; Etoposide; Flow Cytometry; Humans; Keratolytic Agents; Leukemia, Promyelocytic, Acute; Topoisomerase I Inhibitors; Tretinoin; Tumor Cells, Cultured

1995
Activation of the CPP32 apoptotic protease by distinct signaling pathways with differential sensitivity to Bcl-xL.
    The Journal of biological chemistry, 1996, Jul-26, Volume: 271, Issue:30

    Topics: Androstadienes; Apoptosis; bcl-X Protein; Caspase 1; Caspase 3; Caspases; Chromones; Cysteine Endopeptidases; DNA Damage; Enzyme Activation; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Morpholines; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; Signal Transduction; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Wortmannin

1996
[The mechanism of apoptosis induced by anticancer agents in human leukemia HL-60 cells].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1996, Volume: 37, Issue:7

    Topics: Antineoplastic Agents; Apoptosis; Caspase 1; Cysteine Endopeptidases; Etoposide; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Serine Endopeptidases

1996
Differentiation induction therapy with all-trans retinoic acid (ATRA) in a patient with secondary 11q23 leukemia.
    Journal of pediatric hematology/oncology, 1996, Volume: 18, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, Pair 11; Cytarabine; Drug Resistance, Multiple; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Male; Translocation, Genetic; Tretinoin

1996
Acute leukemia during pregnancy: obstetric management and perinatal outcome of two cases.
    European journal of obstetrics, gynecology, and reproductive biology, 1995, Volume: 63, Issue:2

    Topics: Abnormalities, Drug-Induced; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Etoposide; Fatal Outcome; Female; Humans; Leukemia, Promyelocytic, Acute; Mitoxantrone; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Outcome; Recurrence; Thioguanine

1995
Molecular analysis of the t(15;17) translocation in de novo and secondary acute promyelocytic leukemia.
    Leukemia, 1997, Volume: 11 Suppl 3

    Topics: Antineoplastic Agents, Phytogenic; Base Sequence; Blotting, Southern; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Consensus Sequence; Etoposide; Humans; Introns; Leukemia, Promyelocytic, Acute; Neoplasm Proteins; Neoplasms, Second Primary; Nuclear Proteins; Promyelocytic Leukemia Protein; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Transcription Factors; Translocation, Genetic; Tumor Suppressor Proteins

1997
cAMP increasing agents attenuate the generation of apoptosis by etoposide in promonocytic leukemia cells.
    Journal of cell science, 1998, Volume: 111 ( Pt 5)

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cyclic AMP; Enzyme Inhibitors; Etoposide; Gene Expression Regulation, Neoplastic; Genes, myc; Humans; Leukemia, Promyelocytic, Acute; NF-kappa B; Oxidative Stress; Protein Binding; Topoisomerase II Inhibitors; Transcription Factor AP-1; Tumor Cells, Cultured

1998
Bcr-Abl exerts its antiapoptotic effect against diverse apoptotic stimuli through blockage of mitochondrial release of cytochrome C and activation of caspase-3.
    Blood, 1998, Mar-01, Volume: 91, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Cysteine Endopeptidases; Cytarabine; Cytochrome c Group; Enzyme Activation; Etoposide; Fusion Proteins, bcr-abl; Humans; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Promyelocytic, Acute; Membrane Potentials; Mitochondria; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Sphingolipids; Transfection; Tumor Cells, Cultured

1998
Management of acute promyelocytic leukemia relapse in the ATRA era.
    Haematologica, 1998, Volume: 83, Issue:8

    Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Mitoxantrone; Recurrence; Remission Induction; Salvage Therapy; Thioguanine; Treatment Outcome; Tretinoin

1998
Changes in polyamine catabolism in HL-60 human promyelogenous leukaemic cells in response to etoposide-induced apoptosis.
    The Biochemical journal, 1999, Jan-01, Volume: 337 ( Pt 1)

    Topics: Acetyltransferases; Apoptosis; Cell Division; Etoposide; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines

1999
Cryptic insertion (15;17) in a case of acute promyelocytic leukemia detected by fluorescence in situ hybridization.
    Haematologica, 1999, Volume: 84, Issue:1

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cytarabine; Etoposide; Fatal Outcome; Hematopoietic Stem Cell Transplantation; Humans; In Situ Hybridization, Fluorescence; Leukemia, Promyelocytic, Acute; Male; Mitoxantrone; Neoplasm Proteins; Oncogene Proteins, Fusion; Reverse Transcriptase Polymerase Chain Reaction; Translocation, Genetic; Tretinoin

1999
Secondary acute promyelocytic leukemia after treatment with etoposide for Langerhans cell histiocytosis (LCH)
    Medical and pediatric oncology, 1999, Volume: 32, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Child, Preschool; Etoposide; Histiocytosis, Langerhans-Cell; Humans; Leukemia, Promyelocytic, Acute; Male

1999
Early detection by ultrasound scan of severe post-chemotherapy gut complications in patients with acute leukemia.
    Haematologica, 1999, Volume: 84, Issue:3

    Topics: Acute Disease; Adult; Anti-Infective Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dilatation, Pathologic; Enterocolitis; Etoposide; Female; Gallbladder Diseases; Gastrointestinal Diseases; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Intubation, Gastrointestinal; Leukemia; Leukemia, Myelomonocytic, Acute; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Neutropenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome; Ultrasonography

1999
Acute promyelocytic leukemia after treatment for non-Hodgkin's lymphoma with drugs targeting topoisomerase II.
    American journal of hematology, 1999, Volume: 60, Issue:4

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Bone Marrow; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Enzyme Inhibitors; Etoposide; Female; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Lymphoma, Non-Hodgkin; Middle Aged; Receptors, Retinoic Acid; Recurrence; Topoisomerase II Inhibitors; Translocation, Genetic; Tretinoin

1999
Long-term molecular remission in promyelocytic transformation of myeloproliferative disease.
    Leukemia, 1999, Volume: 13, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cytarabine; Daunorubicin; Disease Progression; Etoposide; Female; Humans; Idarubicin; Karyotyping; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Neoplasm Proteins; Oncogene Proteins, Fusion; Polycythemia Vera; Preleukemia; Prognosis; Remission Induction; Thrombocythemia, Essential; Thrombophilia; Translocation, Genetic; Tretinoin

1999
Comparative analysis of different methodological approaches to the in vitro study of drug-induced apoptosis.
    The American journal of pathology, 1999, Volume: 155, Issue:4

    Topics: Annexin A5; Apoptosis; Cell Size; Cisplatin; DNA Fragmentation; Dose-Response Relationship, Drug; Etoposide; Evaluation Studies as Topic; Flow Cytometry; Fluorescein-5-isothiocyanate; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Light; Microscopy, Video; Scattering, Radiation; Time Factors

1999
Treatment of relapsing acute promyelocytic leukemia by all-trans retinoic acid therapy followed by timed sequential chemotherapy and stem cell transplantation. APL Study Group. Acute promyelocytic leukemia.
    Leukemia, 2000, Volume: 14, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Drug Administration Schedule; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Mitoxantrone; Recurrence; Tretinoin

2000
Two secondary leukemias among 15 children given oral etoposide.
    Medical and pediatric oncology, 2001, Volume: 37, Issue:2

    Topics: Child; Etoposide; Humans; Leukemia, Monocytic, Acute; Leukemia, Promyelocytic, Acute; Neoplasms, Second Primary; Neuroblastoma

2001
DNA ligase I is dephosphorylated during the execution step of etoposide-induced apoptosis.
    Cell death and differentiation, 2002, Volume: 9, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; DNA Ligase ATP; DNA Ligases; DNA Replication; Etoposide; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Phosphorylation; Tumor Cells, Cultured

2002
Secondary acute promyelocytic leukemia in a patient with non-Hodgkin's lymphoma treated with VP-16 and MST-16.
    International journal of hematology, 2002, Volume: 75, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Neoplasm Proteins; Neoplasms, Second Primary; Oncogene Proteins, Fusion; Piperazines; Prednisolone; Remission Induction; Tretinoin; Vincristine

2002
Renal cell carcinoma as a secondary malignancy after treatment of acute promyelocytic leukemia.
    Journal of pediatric hematology/oncology, 2001, Volume: 23, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Cerebral Infarction; Child; Chromosomes, Human, Pair 17; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Daunorubicin; Dexamethasone; Etoposide; Humans; Hypertension; Kidney Failure, Chronic; Leukemia, Promyelocytic, Acute; Male; Neoplasms, Second Primary; Obesity; Remission Induction; Thioguanine

2001
Rapid upregulation of telomerase activity in human leukemia HL-60 cells treated with clinical doses of the DNA-damaging drug etoposide.
    Leukemia, 2002, Volume: 16, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Nucleus; Diploidy; DNA Damage; DNA Fragmentation; DNA, Neoplasm; Dose-Response Relationship, Drug; Enzyme Activation; Etoposide; HL-60 Cells; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Telomerase; Up-Regulation

2002
The measurement of nuclear topoisomerase II inhibition in vitro: a possible tool for detecting resistance on a subcellular level in haematopoietic malignancies.
    European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies, 1992, Volume: 30, Issue:2

    Topics: Amsacrine; Antineoplastic Agents; Cell Nucleus; Drug Resistance; Etoposide; Humans; In Vitro Techniques; Leukemia; Leukemia, Promyelocytic, Acute; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1992
Patchy polyneuropathy in acute promyelocytic leukaemia.
    Clinical and laboratory haematology, 1992, Volume: 14, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Combined Modality Therapy; Cytarabine; Daunorubicin; Disseminated Intravascular Coagulation; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Male; Paraneoplastic Syndromes; Peripheral Nervous System Diseases; Remission Induction; Translocation, Genetic; Transplantation, Homologous

1992
Proof of differentiative mode of action of all-trans retinoic acid in acute promyelocytic leukemia using X-linked clonal analysis.
    Blood, 1992, Apr-15, Volume: 79, Issue:8

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Blotting, Southern; Bone Marrow; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Clone Cells; Cytarabine; Daunorubicin; DNA, Neoplasm; Etoposide; Female; Genetic Linkage; Humans; Leukemia, Promyelocytic, Acute; Translocation, Genetic; Tretinoin; X Chromosome

1992
Antagonism between camptothecin and topoisomerase II-directed chemotherapeutic agents in a human leukemia cell line.
    Cancer research, 1991, Feb-15, Volume: 51, Issue:4

    Topics: Amsacrine; Aphidicolin; Blotting, Western; Camptothecin; Colony-Forming Units Assay; Cycloheximide; Daunorubicin; Deoxyadenosines; Dichlororibofuranosylbenzimidazole; Diterpenes; DNA Polymerase II; DNA Replication; Drug Synergism; Etoposide; Female; Humans; Leukemia, Promyelocytic, Acute; Mutagens; RNA; Topoisomerase II Inhibitors; Topotecan; Tumor Cells, Cultured

1991
Response to trans-retinoic acid in an AMLM3 patient resistant to cis-retinoic acid.
    Leukemia research, 1991, Volume: 15, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Lomustine; Male; Middle Aged; Stereoisomerism; Tretinoin

1991
Differential induction of secondary DNA fragmentation by topoisomerase II inhibitors in human tumor cell lines with amplified c-myc expression.
    Cancer research, 1991, Dec-01, Volume: 51, Issue:23 Pt 1

    Topics: Adenocarcinoma; Colonic Neoplasms; DNA Damage; DNA Repair; DNA, Neoplasm; Etoposide; Gene Amplification; Genes, myc; Humans; Leukemia, Promyelocytic, Acute; Teniposide; Tumor Cells, Cultured; Tumor Stem Cell Assay

1991
DNA topoisomerase I as a site of action for 10-hydroxycamptothecin in human promyelocytic leukemia cells.
    Cancer biochemistry biophysics, 1990, Volume: 11, Issue:1

    Topics: Amsacrine; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Division; DNA Damage; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Drug Resistance; Enzyme Inhibitors; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Mutation; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1990
VP-16-induced nucleotide pool changes and poly(ADP-ribose) synthesis: the role of VP-16 in interphase death.
    Experimental cell research, 1989, Volume: 185, Issue:1

    Topics: Benzamides; Cell Line; Cell Survival; DNA Damage; Etoposide; Humans; Interphase; Leukemia, Promyelocytic, Acute; Nucleoside Diphosphate Sugars; Nucleotides; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Protein Biosynthesis; Proteins; Theophylline; Thymidine; Tumor Cells, Cultured

1989
Characterization of an amsacrine-resistant line of human leukemia cells. Evidence for a drug-resistant form of topoisomerase II.
    The Journal of biological chemistry, 1989, Oct-05, Volume: 264, Issue:28

    Topics: Adenosine Triphosphate; Amsacrine; Blotting, Northern; Blotting, Southern; Cell Line; Cell Nucleus; Cell Survival; DNA Topoisomerases, Type II; DNA, Neoplasm; Drug Resistance; Etoposide; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Tumor Cells, Cultured

1989
Role of differential drug uptake, efflux, and binding of etoposide in sensitive and resistant human tumor cell lines: implications for the mechanisms of drug resistance.
    Molecular pharmacology, 1989, Volume: 35, Issue:3

    Topics: Adenosine Triphosphate; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Breast Neoplasms; Dose-Response Relationship, Drug; Drug Resistance; Etoposide; Female; Humans; Leukemia, Promyelocytic, Acute; Membrane Glycoproteins; Sodium Azide; Tumor Cells, Cultured; Vincristine

1989
[Relapse of gingival tumor during hematological remission in acute promyelocytic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1989, Volume: 30, Issue:11

    Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Gingival Neoplasms; Humans; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone; Recurrence; Remission Induction; Vinblastine; Vincristine

1989
Effect of phorbol ester treatment on drug-induced, topoisomerase II-mediated DNA cleavage in human leukemia cells.
    Cancer research, 1988, Dec-01, Volume: 48, Issue:23

    Topics: Amsacrine; Chromatin; DNA; DNA Damage; DNA Topoisomerases, Type II; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1988