etomoxir has been researched along with Insulin Sensitivity in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 6 (46.15) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arduini, A; Ceccarelli, SM; Chomienne, O; Gubler, M | 1 |
| Alvarez-Guardia, D; Barroso, E; Coll, T; Gómez-Foix, AM; Laguna, JC; Palomer, X; Vázquez-Carrera, M | 1 |
| Bosma, M; Hesselink, MK; Langhans, W; Lenaers, E; Nabben, M; Schaart, G; Schrauwen, P; Schrauwen-Hinderling, VB; Timmers, S; van Beurden, D; van Bree, B; Westerterp-Plantenga, MS | 1 |
| Taegtmeyer, H | 1 |
| Cortright, RN; Dudek, RW; Evans, JR; Lust, RM; Manning, SM; Noland, RC; Whitfield, BR; Woodlief, TL | 1 |
| Marazzi, G; Rosano, GM; Volterrani, M | 1 |
| Eason, T; Swislocki, A | 1 |
| Assimacopoulos-Jeannet, F; Guillaume-Gentil, C; Jeanrenaud, B | 1 |
| Davidson, MB; Garvey, D | 1 |
| Bouch, C; Davidson, MB; Lim, J; Marciano, D; Venkatesan, N | 1 |
| Bogardus, C; Caspari, R; Hoyt, C; Mott, DM; Pratley, R; Stone, K | 1 |
| Bentley, B; Dobbins, RL; Esser, V; McGarry, JD; Myhill, J; Szczepaniak, LS | 1 |
| Bitar, MS | 1 |
1 trial(s) available for etomoxir and Insulin Sensitivity
| Article | Year |
|---|---|
Palmitate oxidation rate and action on glycogen synthase in myoblasts from insulin-resistant subjects.
Topics: Adult; Body Mass Index; Carnitine O-Palmitoyltransferase; Cells, Cultured; Enzyme Inhibitors; Epoxy Compounds; Female; Glucose; Glycogen Synthase; Humans; Indians, North American; Insulin Resistance; Kinetics; Male; Middle Aged; Muscle, Skeletal; Obesity; Oxidation-Reduction; Palmitates | 2000 |
12 other study(ies) available for etomoxir and Insulin Sensitivity
| Article | Year |
|---|---|
Carnitine palmitoyltransferase (CPT) modulators: a medicinal chemistry perspective on 35 years of research.
Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Catalytic Domain; Diabetes Mellitus, Type 2; Energy Metabolism; Enzyme Activators; Ethylene Oxide; Heart Failure; Humans; Insulin Resistance; Isoenzymes; Lipid Metabolism; Myocardial Ischemia; Organ Specificity; Protein Conformation; Sequence Homology, Amino Acid; Stereoisomerism | 2011 |
Activation of peroxisome proliferator-activated receptor-{delta} by GW501516 prevents fatty acid-induced nuclear factor-{kappa}B activation and insulin resistance in skeletal muscle cells.
Topics: Analysis of Variance; Animals; Blotting, Western; Carnitine O-Palmitoyltransferase; Cell Line; Cell Nucleus; Electrophoretic Mobility Shift Assay; Epoxy Compounds; Fatty Acids; Humans; Insulin Resistance; Interleukin-6; Mice; Muscle, Skeletal; NF-kappa B; PPAR delta; Protein Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfones; Thiazoles; Thiophenes | 2010 |
Augmenting muscle diacylglycerol and triacylglycerol content by blocking fatty acid oxidation does not impede insulin sensitivity.
Topics: Analysis of Variance; Animals; Blotting, Western; Diglycerides; Epoxy Compounds; Fatty Acids; Fluorescent Antibody Technique; Glucose Transporter Type 4; Humans; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Mitochondria; Muscle Fibers, Skeletal; Oxidation-Reduction; Sarcolemma; Triglycerides | 2012 |
Cardiac metabolism as a target for the treatment of heart failure.
Topics: Acetanilides; Animals; Dogs; Energy Metabolism; Epoxy Compounds; Fatty Acids; Forecasting; Glucagon; Glucagon-Like Peptide 1; Glucose; Heart Failure; Humans; Insulin Resistance; Myocardium; Peptide Fragments; Piperazines; Protein Precursors; Ranolazine; Recombinant Proteins | 2004 |
Peroxisomal-mitochondrial oxidation in a rodent model of obesity-associated insulin resistance.
Topics: Animals; Disease Models, Animal; Epoxy Compounds; Glucose Tolerance Test; Hypoglycemic Agents; Insulin Resistance; Lipids; Liver; Male; Malonyl Coenzyme A; Mitochondria, Liver; Mitochondria, Muscle; Obesity; Oxidation-Reduction; Peroxisomes; Rats; Rats, Sprague-Dawley; Rats, Zucker | 2007 |
Metabolic agents in the management of diabetic coronary patients: a new era.
Topics: Acetanilides; Citric Acid Cycle; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Dichloroacetic Acid; Enzyme Inhibitors; Epoxy Compounds; Humans; Insulin Resistance; Perhexiline; Piperazines; Ranolazine; Trimetazidine; Vasodilator Agents | 2008 |
Glucose tolerance and blood pressure are improved in the spontaneously hypertensive rat by ethyl-2-(6-(4-chlorophenoxy)-hexyl)oxirane-2-carboxylate (etomoxir), an inhibitor of fatty acid oxidation.
Topics: Animals; Blood Glucose; Blood Pressure; Epoxy Compounds; Fatty Acids, Nonesterified; Glucose Tolerance Test; Hypertension; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Oxidation-Reduction; Random Allocation; Rats; Rats, Inbred SHR | 1994 |
Involvement of non-esterified fatty acid oxidation in glucocorticoid-induced peripheral insulin resistance in vivo in rats.
Topics: Animals; Blood Glucose; Carnitine O-Palmitoyltransferase; Corticosterone; Epoxy Compounds; Fatty Acids, Nonesterified; Gluconeogenesis; Glucose; Glucose Clamp Technique; Glucose Transporter Type 4; Glycogen; Hypoglycemic Agents; Insulin; Insulin Resistance; Liver; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscles; Rats; Rats, Zucker; RNA, Messenger | 1993 |
Studies on mechanisms of hepatic insulin resistance in cafeteria-fed rats.
Topics: Animals; Diet; Epoxy Compounds; Fatty Acids, Nonesterified; Glucose; Glucose Clamp Technique; Glucose Tolerance Test; Hyperinsulinism; Insulin Resistance; Liver; Male; Obesity; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Streptozocin | 1993 |
Dexamethasone-induced impairment in skeletal muscle glucose transport is not reversed by inhibition of free fatty acid oxidation.
Topics: Animals; Biological Transport; Carnitine O-Palmitoyltransferase; Deoxyglucose; Dexamethasone; Epoxy Compounds; Fatty Acids, Nonesterified; Glucocorticoids; Glucose; Glucose Transporter Type 4; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Oxidation-Reduction; Rats; Rats, Sprague-Dawley | 1996 |
Prolonged inhibition of muscle carnitine palmitoyltransferase-1 promotes intramyocellular lipid accumulation and insulin resistance in rats.
Topics: Adipocytes; Adipose Tissue; Animals; Body Weight; Carnitine O-Palmitoyltransferase; Dietary Fats; Eating; Enzyme Inhibitors; Epoxy Compounds; Glucose; Glucose Clamp Technique; Hyperinsulinism; In Vitro Techniques; Insulin Resistance; Isoenzymes; Lipid Metabolism; Magnetic Resonance Spectroscopy; Male; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Time Factors | 2001 |
Co-administration of etomoxir and RU-486 mitigates insulin resistance in hepatic and muscular tissues of STZ-induced diabetic rats.
Topics: Animals; Carnitine O-Palmitoyltransferase; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Enzyme Inhibitors; Epoxy Compounds; Fatty Acids, Nonesterified; Glucose; Hormone Antagonists; Insulin Resistance; Liver; Male; Mifepristone; Mitochondria; Muscle, Skeletal; Rats; Rats, Wistar | 2001 |