etodolac has been researched along with Urinary Bladder Neoplasms in 2 studies
Etodolac: A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).
etodolac : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.
Urinary Bladder Neoplasms: Tumors or cancer of the URINARY BLADDER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We examined the cytotoxicity of etodolac against three human bladder cancer cell lines, T24, 5637, and KK47, and performed quantitative reverse transcriptase-polymerase chain reaction to measure the mRNA expression of COX-2, and E-cadherin." | 7.74 | Etodolac, a selective cyclooxygenase-2 inhibitor, induces upregulation of E-cadherin and has antitumor effect on human bladder cancer cells in vitro and in vivo. ( Bito, T; Fujisawa, M; Gotoh, A; Hamada, K; Kawabata, M; Okamoto, A; Shigemura, K; Shirakawa, T, 2008) |
| "We used three Cox-2 inhibitors, etodolac, celecoxib and NS-398 and three human bladder cancer cell lines, T24, 5637 and KK47, in this study." | 3.77 | In vitro and in vivo inhibitory effect of three Cox-2 inhibitors and epithelial-to-mesenchymal transition in human bladder cancer cell lines. ( Adhim, Z; Bito, T; Fujisawa, M; Kawabata, M; Lee, KM; Matsuoka, T; Nibu, K; Shigemura, K; Shirakawa, T, 2011) |
| "We examined the cytotoxicity of etodolac against three human bladder cancer cell lines, T24, 5637, and KK47, and performed quantitative reverse transcriptase-polymerase chain reaction to measure the mRNA expression of COX-2, and E-cadherin." | 3.74 | Etodolac, a selective cyclooxygenase-2 inhibitor, induces upregulation of E-cadherin and has antitumor effect on human bladder cancer cells in vitro and in vivo. ( Bito, T; Fujisawa, M; Gotoh, A; Hamada, K; Kawabata, M; Okamoto, A; Shigemura, K; Shirakawa, T, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adhim, Z | 1 |
| Matsuoka, T | 1 |
| Bito, T | 2 |
| Shigemura, K | 2 |
| Lee, KM | 1 |
| Kawabata, M | 2 |
| Fujisawa, M | 2 |
| Nibu, K | 1 |
| Shirakawa, T | 2 |
| Okamoto, A | 1 |
| Hamada, K | 1 |
| Gotoh, A | 1 |
2 other studies available for etodolac and Urinary Bladder Neoplasms
| Article | Year |
|---|---|
In vitro and in vivo inhibitory effect of three Cox-2 inhibitors and epithelial-to-mesenchymal transition in human bladder cancer cell lines.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cadherins; Cell Dedifferentiation; Cell Line, Tumor; Cell | 2011 |
Etodolac, a selective cyclooxygenase-2 inhibitor, induces upregulation of E-cadherin and has antitumor effect on human bladder cancer cells in vitro and in vivo.
Topics: Animals; Apoptosis; Cadherins; Carcinoma, Transitional Cell; Cell Line, Tumor; Cyclooxygenase 2; Cyc | 2008 |