Page last updated: 2024-10-26

etodolac and Nerve Sheath Neoplasms

etodolac has been researched along with Nerve Sheath Neoplasms in 1 studies

Etodolac: A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).
etodolac : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.

Nerve Sheath Neoplasms: Neoplasms which arise from nerve sheaths formed by SCHWANN CELLS in the PERIPHERAL NERVOUS SYSTEM or by OLIGODENDROCYTES in the CENTRAL NERVOUS SYSTEM. Malignant peripheral nerve sheath tumors, NEUROFIBROMA, and NEURILEMMOMA are relatively common tumors in this category.

Research Excerpts

ExcerptRelevanceReference
"Malignant peripheral nerve sheath tumor (MPNST) is a rare and aggressive soft tissue sarcoma for which effective treatments have not yet been established."1.40Overexpression of cyclooxygenase-2 in malignant peripheral nerve sheath tumor and selective cyclooxygenase-2 inhibitor-induced apoptosis by activating caspases in human malignant peripheral nerve sheath tumor cells. ( Abe, M; Hakozaki, M; Hojo, H; Kikuchi, S; Konno, S; Nagasawa, H; Nishida, J; Ogose, A; Tajino, T; Tsuchiya, T; Yamada, H; Yanagisawa, M, 2014)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hakozaki, M1
Tajino, T1
Konno, S1
Kikuchi, S1
Yamada, H1
Yanagisawa, M1
Nishida, J1
Nagasawa, H1
Tsuchiya, T1
Ogose, A1
Abe, M1
Hojo, H1

Other Studies

1 other study available for etodolac and Nerve Sheath Neoplasms

ArticleYear
Overexpression of cyclooxygenase-2 in malignant peripheral nerve sheath tumor and selective cyclooxygenase-2 inhibitor-induced apoptosis by activating caspases in human malignant peripheral nerve sheath tumor cells.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Apoptosis; Caspase Inhibitors; Caspases; Cell Line, Tumo

2014