etodolac has been researched along with Neoplasm Metastasis in 3 studies
Etodolac: A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).
etodolac : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.
Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Several key metastasis-related mediators, such as vascular endothelial growth factor-A, vascular endothelial growth factor-C, and matrix metalloproteinase-9, were inhibited in the presence of etodolac as compared to untreated M2 macrophages." | 1.39 | Cyclooxygenase-2 inhibition blocks M2 macrophage differentiation and suppresses metastasis in murine breast cancer model. ( Na, YR; Seok, SH; Son, DI; Yoon, YN, 2013) |
| "When tumors reached 100 mm, mice were treated with CpG-C/vehicle, and 24 hours later the tumor was excised along with P+E/vehicle treatment." | 1.37 | Improving postoperative immune status and resistance to cancer metastasis: a combined perioperative approach of immunostimulation and prevention of excessive surgical stress responses. ( Ben-Eliyahu, S; Benish, M; Goldfarb, Y; Levi, B; Melamed, R; Sorski, L, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Na, YR | 1 |
| Yoon, YN | 1 |
| Son, DI | 1 |
| Seok, SH | 1 |
| Glasner, A | 1 |
| Avraham, R | 1 |
| Rosenne, E | 1 |
| Benish, M | 2 |
| Zmora, O | 1 |
| Shemer, S | 1 |
| Meiboom, H | 1 |
| Ben-Eliyahu, S | 2 |
| Goldfarb, Y | 1 |
| Sorski, L | 1 |
| Levi, B | 1 |
| Melamed, R | 1 |
3 other studies available for etodolac and Neoplasm Metastasis
| Article | Year |
|---|---|
Cyclooxygenase-2 inhibition blocks M2 macrophage differentiation and suppresses metastasis in murine breast cancer model.
Topics: Animals; Cell Differentiation; Cyclooxygenase 2 Inhibitors; Cytokines; Disease Models, Animal; Etodo | 2013 |
Improving survival rates in two models of spontaneous postoperative metastasis in mice by combined administration of a beta-adrenergic antagonist and a cyclooxygenase-2 inhibitor.
Topics: Adrenergic beta-Antagonists; Amputation, Surgical; Animals; Antineoplastic Combined Chemotherapy Pro | 2010 |
Improving postoperative immune status and resistance to cancer metastasis: a combined perioperative approach of immunostimulation and prevention of excessive surgical stress responses.
Topics: Analysis of Variance; Animals; Chemotherapy, Adjuvant; Disease Models, Animal; Etodolac; Female; Imm | 2011 |