etodolac has been researched along with Muscle Contraction in 3 studies
Etodolac: A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).
etodolac : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Etodolac was found to have no effect on 5-lipoxygenase activity." | 1.29 | Effect of anti-inflammatory agent etodolac on antigen-induced contractions of the trachea and lung parenchyma of guinea pigs. ( Hamada, K; Inoue, K; Kimura, K; Shibata, Y; Ueda, F, 1994) |
| "Etodolac (Ultradol) is a new tetrahydropyrano-indole derivative which has shown pronounced analgesic and antiinflammatory properties." | 1.27 | Comparative effects of etodolac, indomethacin, and benoxaprofen on icosanoid biosynthesis. ( Borgeat, P; Salari, H; Saura, C; Sirois, P, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Van Hoogmoed, LM | 1 |
| Snyder, JR | 1 |
| Harmon, FA | 1 |
| Sirois, P | 1 |
| Saura, C | 1 |
| Salari, H | 1 |
| Borgeat, P | 1 |
| Inoue, K | 1 |
| Hamada, K | 1 |
| Ueda, F | 1 |
| Shibata, Y | 1 |
| Kimura, K | 1 |
3 other studies available for etodolac and Muscle Contraction
| Article | Year |
|---|---|
In vitro investigation of the effects of cyclooxygenase-2 inhibitors on contractile activity of the equine dorsal and ventral colon.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Colon; Cyclooxygenase 2; Cyclooxygenase | 2002 |
Comparative effects of etodolac, indomethacin, and benoxaprofen on icosanoid biosynthesis.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Arachidonate Lipoxygenases; Blood Platelets; Catechols; | 1984 |
Effect of anti-inflammatory agent etodolac on antigen-induced contractions of the trachea and lung parenchyma of guinea pigs.
Topics: Animals; Asthma; Benzoquinones; Disease Models, Animal; Etodolac; Guinea Pigs; Immunization, Passive | 1994 |