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etodolac and Liver Dysfunction

etodolac has been researched along with Liver Dysfunction in 2 studies

Etodolac: A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).
etodolac : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.

Research Excerpts

ExcerptRelevanceReference
" To investigate the effect of disease states or concomitant drug administration on a patient's response to etodolac, additional pharmacokinetic studies were carried out in special populations."1.29Pharmacokinetic profile of etodolac in special populations. ( Benet, LZ, 1994)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benet, LZ1
Sho, Y1
Ishiodori, T1
Oketani, M1
Kubozono, O1
Nakamura, A1
Takeuchi, A1
Morino, A1
Arima, T1

Trials

1 trial available for etodolac and Liver Dysfunction

ArticleYear
Effects of urinary metabolites of etodolac on diagnostic tests of bilirubin in urine.
    Arzneimittel-Forschung, 1999, Volume: 49, Issue:7

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Bilirubin; Chromatography, High Pressure Liquid; Diaz

1999

Other Studies

1 other study available for etodolac and Liver Dysfunction

ArticleYear
Pharmacokinetic profile of etodolac in special populations.
    European journal of rheumatology and inflammation, 1994, Volume: 14, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Drug Interactions; Etodolac; Humans; Kidney; Kidney Diseases; Liver;

1994