etodolac has been researched along with Liver Cirrhosis in 2 studies
Etodolac: A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).
etodolac : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.
Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Etodolac is a chiral nonsteroidal anti-inflammatory drug (NSAID) that is marked as the racemate." | 2.39 | Etodolac clinical pharmacokinetics. ( Brocks, DR; Jamali, F, 1994) |
| " The mean half-life (t1/2) was 6 to 7 hours." | 2.38 | Profile of etodolac: pharmacokinetic evaluation in special populations. ( Brater, DC; Lasseter, KC, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brocks, DR | 1 |
| Jamali, F | 1 |
| Brater, DC | 1 |
| Lasseter, KC | 1 |
2 reviews available for etodolac and Liver Cirrhosis
| Article | Year |
|---|---|
Etodolac clinical pharmacokinetics.
Topics: Aging; Animals; Drug Interactions; Etodolac; Humans; Intestinal Absorption; Kidney Diseases; Liver C | 1994 |
Profile of etodolac: pharmacokinetic evaluation in special populations.
Topics: Administration, Oral; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Etodolac; Half-Life; Hum | 1989 |