Page last updated: 2024-10-26

etodolac and Ischemia

etodolac has been researched along with Ischemia in 3 studies

Etodolac: A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).
etodolac : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
" Here, we evaluated the influence of aspirin and etodolac, a selective cyclooxygenase-2 inhibitor, on neovascularization using a murine ischemia hind limb model."3.76The cyclooxygenase-2 selective inhibitor, etodolac, but not aspirin reduces neovascularization in a murine ischemic hind limb model. ( Hisatome, I; Kita, Y; Shimizu, T; Tanaka, K; Tsujimoto, S; Uozumi, N; Yamamoto, Y; Yoshida, A, 2010)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hirono, J1
Sanaki, H1
Kitada, K1
Sada, H1
Suzuki, A1
Lie, LK1
Segi-Nishida, E1
Nakagawa, K1
Hasegawa, H1
Tanaka, K1
Yamamoto, Y1
Tsujimoto, S1
Uozumi, N1
Kita, Y1
Yoshida, A1
Shimizu, T1
Hisatome, I1
Tomlinson, JE1
Wilder, BO1
Young, KM1
Blikslager, AT1

Other Studies

3 other studies available for etodolac and Ischemia

ArticleYear
Expression of tissue inhibitor of metalloproteinases and matrix metalloproteinases in the ischemic brain of photothrombosis model mice.
    Neuroreport, 2018, 02-07, Volume: 29, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain; Disease Models, Animal; Endothelia

2018
The cyclooxygenase-2 selective inhibitor, etodolac, but not aspirin reduces neovascularization in a murine ischemic hind limb model.
    European journal of pharmacology, 2010, Feb-10, Volume: 627, Issue:1-3

    Topics: Animals; Aspirin; Bone Marrow Cells; Cell Transplantation; Cyclooxygenase 1; Cyclooxygenase 2; Cyclo

2010
Effects of flunixin meglumine or etodolac treatment on mucosal recovery of equine jejunum after ischemia.
    American journal of veterinary research, 2004, Volume: 65, Issue:6

    Topics: Animals; Biological Transport; Blotting, Western; Clonixin; Cyclooxygenase 1; Cyclooxygenase 2; Cycl

2004